CN107050275A - Chinese medicinal preparation for relieving snake venom and preparation method thereof - Google Patents
Chinese medicinal preparation for relieving snake venom and preparation method thereof Download PDFInfo
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- 235000021286 stilbenes Nutrition 0.000 description 1
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Abstract
The invention relates to the field of traditional Chinese medicine preparations for detoxifying snake venom, in particular to a traditional Chinese medicine preparation for detoxifying snake venom and a preparation method thereof, wherein the effective components of the traditional Chinese medicine preparation are prepared from the following raw materials in parts by weight: 1-100 parts of angelica dahurica, 1-100 parts of astragalus root, 1-100 parts of liquorice, 1-100 parts of fructus forsythiae, 1-100 parts of thunberg fritillary bulb, 1-100 parts of folium isatidis, 1-100 parts of goldthread root, 1-100 parts of fructus evodiae, 1-100 parts of radix clematidis, 1-100 parts of trogopterus dung, 1-100 parts of rheum officinale, 1-100 parts of ligusticum wallichii, 1-100 parts of asarum, 0.5-50 parts of centipede and the like. The invention can effectively treat the snake venom of the cobra or the bungarus multicinctus, can astringe and promote granulation, promotes wound healing, can repair the wound by external application, and does not leave scars; has no side effect and the like.
Description
Technical field
Antidoted against snake bite field of traditional Chinese the present invention relates to one kind, and in particular in a kind of solution cobra, Bungarus multicinctus snake venom
Medicine preparation and preparation method thereof.
Background technology
China working people during combating the disease, by practice, constantly recognizes, gradually accumulated for thousands of years
Abundant medicinal knowledge.Because period in romote antiquity word is not emerging, these knowledge can only have word later by transmission from master to disciple oral instruction,
Just gradually record, Chinese medicine occurs in that medical book.These books serve summary forefathers' experience and are easy to spread and promote
Effect.Existing thousands of years history of traditional Chinese medicine, is the long-term extremely rich experience struggled with disease of our people
Summarize, have huge contribution for the prosperity of the Chinese nation.
Medicine is indispensable part in people's life, moreover, China is large agricultural country, the frequent labor between field of people
Make, some poisonous snakes can be run into unavoidably.Poisonous snake can give people it is fatal be its snake venom, ophidism works as venomous snake bite human body
When, its venom injects human body by ditch tooth or pipe tooth, causes a variety of parts and complete by blood circulation, distribution to whole body
Body poisoning symptom.
Most common snake venom can be divided into four classes:One is neurotoxin, such as banked krait, Bungarus multicinctus;Two be blood circulation toxin,
Such as green bamboo snake, agkistrodon acutus;Three be mixing endotoxin, both contains neurotoxin, again containing blood circulation poison element, such as cobra,
King cobra etc.;Four be cytotoxin, such as sea snake.Land inside, common is neurotoxin, blood circulation toxin, admixture poison
Element.
Neurotoxin can cause occur constitutional symptom drastically in a few hours after wound, and patient is excited uneasy, pain groan,
Whole-body muscle trembles, and foams at the mouth, dysphagia, expiratory dyspnea, finally crouch ground do not rise, whole body twitch, paralysis of respiratory muscle and it is dead.
Blood circulation toxin can cause to be snapped the rapid swelling in injury, harden, bleed incessantly, and severe pain, skin is in atropurpureus, often
Generation cutaneous necrosis, enlargement of lymph nodes.It is can spread through 6-8 hours to head, neck, four limbs and the small of the back.Sick dog trembles, body temperature
Rise, aroused in interest to accelerate, expiratory dyspnea, it is impossible to stand.Nosebleed, hematuria is twitched.If do not obtained in 4 hours after biting effectively
Treatment is then last dead because of heart failure or shock.
The traditional Chinese medical science is to the understanding of snake venom, early in the Sui Dynasty《The General Treatise on the Cause and Symptoms of Diseases》In be just documented.In long-term medical practice
In, summed up a whole set of effective treatment method, i.e., in control, control outside or Nei Zhi is with controlling and being combined outside.
The patent document about antidoting against snake bite is retrieved, some are enumerated as follows:
1st, Chinese patent<Application number>201410702726.X<Denomination of invention>A kind of Chinese medicine antidoted against snake bite<Applicant>Quanjiang tribute
Ju Yuan tea processing factories<Address>239500 Shi Pei towns Zhou Gang villages of Chuzhou City Quanjiao County, Anhui Province<Inventor>Ma Chaodong<Summary>The present invention
It is related to a kind of Chinese medicine antidoted against snake bite, by weight, is formulated by following component:8-12 parts of trilliaceae, 5-7 parts of nandina, awns
5-8 parts of nitre, 1-2 parts of ramulus et uncus uncariae, 12-15 parts of Sculellaria barbata, 2-5 parts of bittersweet, 3-6 parts of ginseng, 1-3 parts of the stem of noble dendrobium, 3-5 parts of chrysanthemum indicum;This
Invent the Chinese medicine antidoted against snake bite provided to summarize by long term test, formula is optimized, blood circulation poison element can be substantially reduced
What class was bitten disables and fatal rate, especially the class such as green bamboo snake, point kiss Pallas pit viper, efficient higher.
2nd, Chinese patent<Application number> 201610346809.9<Denomination of invention>A kind of urgent antidote for alleviating snake venom<
Applicant>Nanjing Ze Lang medical sciences Co., Ltd<Address>210046 Nanjings Qixia District Yao Hua streets Gan Jia sides
6 building, No. 108 Building 05<Inventor>Yang Chengdong<Summary>The present invention relates to a kind of urgent antidote for alleviating snake venom, it is by following
Raw material is made:Windproof 10-16 parts, 8-12 parts of the root of Dahurain angelica, 8-16 parts of excrementum pteropi, 12-20 parts of Herba Andrographitis, Sculellaria barbata 20-40
Part, 14-22 parts of ginger, product produced by the present invention have antibacterial, antiviral, antipyretic, anti-inflammatory effect, appearance are stung for snake
Local redness, pain, necrosis, The blood streamed down etc. with good curative effect.
3rd, Chinese patent<Application number>200610036469.6<Denomination of invention>Anti-virus snake medicine wine<Applicant>Xu Xuebing
<Address>512438 Shaoguan City of Guangdong Province Nanxiong pearl town pool east directorial area<Inventor>Xu Xuebing<Summary>The present invention relates to one
Anti-virus snake medicine wine, including immersion Chinese medicine are planted, immersion Chinese medicine includes pseudo-ginseng, the bark of eucommia, treats knife bamboo, QIYEHUA, snake gall.
The present invention can cure the disease, diseases prevention, can antidote against snake bite again, poisonous insect poison, moreover it is possible to bactericidal antiphlogistic, promote body anti-cancer, anticancer, removing toxic substances, row
Poison, clearing damp, rush body are sturdy, have no toxic side effect.The crude drug source that the present invention is used is convenient, manufacture craft simple possible, while this
Invention belongs to antitoxin Inflammation-diminishealth-care health-care wine, is easy to preserve.
4th, Chinese patent<Application number>201110323244.X<Denomination of invention>A kind of medicinal liquor for treating snake venom<Applicant>
Zheng Yang<Address>515041 Shantou City, Guangdong Province Longhu District Zhu Chi streets Chaoyang village North 9 Building B<Inventor>Zheng Yang<Summary>
The present invention provides a kind of medicinal liquor for treating snake venom, is made up of following components and parts by weight:Bury gold 80~85;Evodia lepta merr 80~
85;Thickleaf Croton Root 80~85;Hypericum japonicum 45~50;Chinese lobelia 45--50;Rice wine 800~1500:To be buried gold, evodia lepta merr, chicken bone
Perfume, hypericum japonicum, Chinese lobelia are ground, and put in container, add rice wine, and sealing immersion can be used after 1 month.It is an object of the invention to provide
A kind of medicinal liquor for treating snake venom, bites for treating snake venom.
5th, Chinese patent<Application number>201410682833.0<Denomination of invention>A kind of Chinese traditional medicine composition for being used to treat snake venom
Thing<Applicant>Wu Yanhua<Address>242200 red flag communities of Guangde County of Xuancheng City of Anhui Province Tao Zhou towns flood Tianmen<Inventor>It is military
Yan Hua<Summary>A kind of Chinese medicine composition for treating snake venom, is related to Chinese medicine preparation technical field, composed of the following components:It is northern husky
Ginseng, the tuber of dwarf lilyturf, the stem of noble dendrobium, radix scrophulariae, RADIX ANGELICAE SINEINSIS, the fruit of glossy privet, the fruit of Chinese magnoliavine, licorice, radix pseudostellariae, Poria cocos, the dried rhizome of rehmannia, dried orange peel.The present invention is carried
The Chinese medicine composition of the treatment snake venom convalescence of confession, the patient of centering snake venom has good curative effect, especially to convalescence
Patient, effect is particularly evident, can effectively alleviate influence and stimulation of the snake venom to nerve and body, and to body fluid loss, fire
Disease severe patient has good curative effect, clothes for patients safe without toxic side effect.
From the document retrieved we it can be appreciated that in above-mentioned prescription it is perhaps effective in cure, effect is too wide.After all, people
Only once, the snake venom of not all poisonous snake is suitable for same prescription to life, just in case therefore delaying treatment, consequence is very serious
's.
The content of the invention
The purpose of the present invention is to overcome defect of the prior art, and provides a kind of Chinese medicine preparation antidoted against snake bite and its preparation
Method, the Chinese medicine preparation has good therapeutic effect for the snake venom of cobra, Bungarus multicinctus, and outer wiping is effectively repaiied to wound
It is multiple, scar or sequelae are not stayed;The Chinese medicine preparation is easy to operate in manufacturing process, can the maximized reservation property of medicine.
In order to realize the purpose of foregoing invention, the technical scheme taken is:
A kind of Chinese medicine preparation antidoted against snake bite, its active ingredient is to be prepared from the following raw materials in parts by weight:
1~100 part of the root of Dahurain angelica, 1~100 part of the Radix Astragali, 1~100 part of radix glycyrrhizae, 1~100 part of the capsule of weeping forsythia
1~100 part of bulb of thunberg fritillary, 1~100 part of folium isatidis, 1~100 part of coptis root, 1~100 part of Wu's cornel
1~100 part of the root of Chinese clematis, 1~100 part of excrementum pteropi, 1~100 part of rheum officinale, 1~100 part of Ligusticum wallichii
1~100 part of asarum, 0.5~50 part of centipede.
Above-described Chinese medicine preparation is aqua or pulvis.
The preparation method of above-described aqua includes following steps:
(1)By the root of Dahurain angelica, the Radix Astragali, radix glycyrrhizae, folium isatidis, coptis root, the root of Chinese clematis, rheum officinale, Ligusticum wallichii and asarum, impurity elimination is cleaned, drained away the water,
It is put into dryer and is dried, the temperature control in dryer is 70~80 DEG C, it is 10%~12% to be dried to water content, standby;
(2)The capsule of weeping forsythia is weeded out into seed and impurity, drying in dryer is put into, it is standby;
(3)By the net material of bulb of thunberg fritillary, drying in dryer is placed into, it is standby;
(4)By the excrementum pteropi of collection, net material is put into drying in dryer, standby;
(5)Centipede living is collected, net material is stored in vial, standby;
(6)By above-mentioned steps(1)Obtained medicinal material carries out the respective segment of correspondence or section, then extracts each medicine by weight
Material, is well mixed, is put in vial;It is standby;
(7)By weight toward step(6)Step is separately added into the vial of middle gained(2)、(3)With(4)After middle drying
The capsule of weeping forsythia, bulb of thunberg fritillary, excrementum pteropi;It is standby;
(8)By weight toward step(7)Step is added in the vial of middle gained(5)Centipede, then by weight of material add 2
50 DEG C of~5 times~55 DEG C of grain wines, sealing immersion 15~45 days, that is, be made the aqua of the Chinese medicine preparation antidoted against snake bite.
The preparation method of above-described pulvis includes following steps:
(1)By the root of Dahurain angelica, the Radix Astragali, radix glycyrrhizae, the capsule of weeping forsythia, bulb of thunberg fritillary, folium isatidis, coptis root, Wu's cornel, the root of Chinese clematis, rheum officinale, Ligusticum wallichii and asarum, go
It is miscellaneous to clean, drain away the water, be put into dryer and dried, the temperature control in dryer is 70~80 DEG C, is dried to water content
It is standby for 10%~12%;
(2)By the excrementum pteropi of collection, net material is put into drying in dryer, standby;
(3)Centipede living will be collected, net material is put into drying in dryer, removes cephalopodium, standby;
(4)By above-mentioned steps(1)、(2)With(3)In obtained medicinal material carry out correspondence and each chopping or crush, then by weight
Number weighs each medicinal material, sterilizes, and is well mixed, and reuses micronizer and carries out ultramicro grinding;Pack, every bag of 2g is examined, qualified
Product are put in storage, and produce the pulvis of the Chinese medicine preparation antidoted against snake bite.
The above-described Chinese medicine preparation antidoted against snake bite be prepared in cobra, Bungarus multicinctus snake venom application.
The wine that above-described grain wine is brewed by grains such as liquor made from sorghum, rice wine, sweet potato wine, cassiris.
Bite by Naja naja atra is directed to, the method for Chinese medicinal using the present invention is:
(1)The poison that goes out is carried out to wound;I.e. with the potassium permanganate dilution that normal saline dilution potassium permanganate is 0.1%, in wound
Place, the potassium permanganate dilution of injection 0.1% is gone out poison, and injection volume can be carried out according to wound situation;
(2)Take 20~40ml of aqua of the present invention orally, three times a day;Or using the pulvis of the present invention, often bag pulvis is with the 20 of 5ml
~30 DEG C of white wine modulation, then orally, three times a day;Until poisoning symptom is eliminated.Or oral while, can be with aqua or powder
After agent is using white wine modulation, outer wiping whole body.
Induced By Coral Snake Bite is directed to, the method for Chinese medicinal using the present invention is:
(1)The poison that goes out is carried out to wound;I.e. with the potassium permanganate dilution that normal saline dilution potassium permanganate is 0.1%, in wound
Place, the potassium permanganate dilution of injection 0.1% is gone out poison, and injection volume can be carried out according to wound situation;
(2)Take 20~40ml of aqua of the present invention orally, three times a day;Or using the pulvis of the present invention, often bag pulvis is white with 5ml
Vinegar is modulated, then orally, three times a day;Until poisoning symptom is eliminated.Or oral while, light-coloured vinegar can be used with aqua or pulvis
After modulation, outer wiping whole body.
Above-mentioned its preparing raw material of the Chinese medicine preparation antidoted against snake bite, Ke Yicong《Chinese Pharmacopoeia》It is found with other Chinese medicine handbooks
Alias, latin name and the place of production, usage, the mechanism in order to understand present invention supression disease, now to effect of above-mentioned each taste active compound
It is summarized as follows with pharmacological:
(1)The root of Dahurain angelica, Classification system:Angelica dahurica (Fisch. ex Hoffm.)Benth. et Hook. f. ex Franch. et Sav), perennial tall and big draft is high 1-2.5 meters, root cylinder, 2-5 centimetres of basal part of stem footpath, basal leaf one
Return pinnation, universal umbel basidixed or side life, fruit Long Circle to oval.It is distributed in the northeast and North China of China's Mainland
Etc. ground, be grown on the area of 200 meters to 1.500 meters of height above sea level, be typically born in sylvan life, border, by small stream, shrubbery and mountain valley meadow.【Property
Taste channel tropism】It is warm-natured, pungent, gas fragrance, slight bitter.Enter lung, spleen, stomach.For Yangming Channel guiding drug.【Function is with curing mainly】Wind-dispelling, it is dry
It is wet, subside a swelling, analgesic.Control headache, pain in the supra-orbital bone, dentalgia, nasosinusitis, cold-dampness stomachache, intestines wind anal fistula, leukorrhea with reddish discharge, ulcer sores, skin
Skin is dry to itch, mange.
(2)The Radix Astragali, latin name:Astragalus membranaceus (Fisch.) Bunge., alias has cotton stilbene, Huang
Over sixty years of age, only mulberry, another name for Sichuan Province fat, hundred etc..Perennial herb is high 50-100 centimetres.Main root is plump, wooden, normal branch, canescence.Stem is straight
Vertical, top multi-branched has thin rib, by white pubescence.Perennial herb is high 50-100 centimetres.Originate in the Inner Mongol, Shanxi, Gansu,
The ground such as Heilungkiang.【Meridian distribution of property and flavor】It is sweet, tepor;Return lung, spleen, liver and kidney channel.【Function is with curing mainly】Invigorating qi for consolidating superficies, arrest sweating admittedly take off, support
The effect of sore myogenic, inducing diuresis for removing edema.For treating treatment deficiency of vital energy weak, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle
Subcutaneous ulcer hardly possible is burst, burst for a long time and does not holds back, blood deficiency chlorosis, Heat Diabetes, chronic nephritis, albuminuria, diabetes etc..Astragalus root invigorating middle warmer and replenishing QI, it is raw
With solid table torr sore.
(3)Radix glycyrrhizae, Classification system:Glycyrrhiza uralensis Fisch., alias has Herba Hedyotis cantonensis root, Radix Glycyrrhizae, powder
Radix glycyrrhizae, Glycyrrhiza Uralensis, pulse family, Glycyrrhiza perennial herb, root are sturdy with root-like stock, are a kind of help Chinese herbal medicines.To human body
A kind of good medicine, medicinal part is root and rhizome, and Medicinal Materials Characters root is long 25~100 centimetres in cylinder, diameter 0.6~3.5
Centimetre.Crust is elastic to differ, surface rufous or taupe brown.Rhizome is in cylinder, and surface, which has in the middle part of bud scar, section, marrow.Gas
It is micro-, taste sweet tea and it is special.Major function is clearing heat and detoxicating, expelling phlegm and arresting coughing, gastral cavity abdomen etc..Happiness is dark moist, the low drying of the long temperature of sunshine
Weather.Arid, semiarid desert steppe, desert edge and loess hill area are grown in radix glycyrrhizae more.Root and root-like stock supply medicine
With.【Meridian distribution of property and flavor】It is sweet, put down, it is nontoxic;Enter spleen, stomach, lung channel.【Function is with curing mainly】Invigorating middle warmer and replenishing QI;Relieving spasm to stop pain;Moisten the lung and relieve the cough;
Purging intense heat and detonicating;Coordinating the drug actions of a prescription.Main burnout deficiency of food;The thin face of flesh is yellow;Palpitation;Stomachache loose stool;Four limbs contraction;Hysteria;Cough
Cough asthma;Abscess of throat;Ulcerative carbuncle swells and ache;Infant fetal toxin;And medicine, food poisoning.For weakness of the spleen and the stomach, lassitude hypodynamia, palpitaition
Shortness of breath, coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction, carbuncle sore tumefacting virus alleviate drug toxicity, strong.
(4)The capsule of weeping forsythia, latin name:Forsythia suspensa, alias has chrysanthemum bar, Huang Shoudan.It is Oleaceae Forsythia Vahl
Plant.Capsule of weeping forsythia early spring elder generation's leaf is bloomed, and the flowers are in blossom, and fragrance is light gorgeous, and full branch is golden yellow, gorgeous lovely, is early spring excellent sight flowering shrub, plant height
Up to 3 meters, limb is grown thickly, and sprig yellow, arch is sagging, hollow.Leaf is to life, single leaf or three leaflets, avette or ovate-elliptic,
Edge has tooth.Corolla yellow, 1-3 is born in axil;Fruit ovoid, ovate-elliptic or oblong, tip beak are tapering, surface
Sparsely grow hole skin;Carpopodium is long 0.7-1.5 centimetres.The month at florescence 3-4, the fruiting period 7-9 months.【Meridian distribution of property and flavor】Hardship, it is cool;Enter the heart, liver, gallbladder channel.
【Function is with curing mainly】Heat-clearing, removing toxic substances, dissipating bind, detumescence.Control warm, erysipelas, macula, large carbuncle pyogenic infections, scrofula, urine leaching closes.
(5)Bulb of thunberg fritillary, latin name:Bulbus Fritillariae Thunbergii, alias has fritillaria thunbergii, Bulbus Fritillariae Thunbergii, Bulbus Fritillariae Thunbergii
Female, big fritillaria;Fritillaria, river person is sweet optimal:Western person's taste is thin to take second place, and Xiangshan person's slight bitter is taken second place again, and one kind is big and hardship person is only capable of solution
Poison.And go the heart to use.All lung channel medicines are all when removing the heart, not only fritillaria.Successive dynasties document in the past, and not yet explicitly discrete tendril-leaved fritillary bulb, bulb of thunberg fritillary,
The native special bar of shellfish, it is extremely bright《Book on Chinese herbal medicine is just》Start from after fritillaria bar, Li not go up fritillaria one, meaning is this product.Clearly《Hundred careless mirrors》Begin【Property
Taste channel tropism】Bitter;It is cold in nature.Return lung;The heart channel of Hang-Shaoyin.【Function is with curing mainly】Clearing heat and eliminating phlegm;Sending down abnormally ascending cough-relieving;Mass dissipating and swelling eliminating;Wind-heat or phlegm heat
Cough;Lung carbuncle pyemesis;Scrofula goiter and tumor;Sore and toxic.
(6)Folium isatidis, latin name:Isatis indigotica Fortune, alias has Lan Ye, blue dish etc..Dried leaf is wrinkled
Lumps are weaved into, are crushed sometimes, in celadon or yellowish-brown.Complete leaf falls lanceolar in oblong to long round shape, long by 4~
It is 11 centimetres, wide 1~3 centimetre, full edge or wavy;Tip blunt point, base portion is gradually narrow, prolongs into wing, and visible point-like is dashed forward sometimes above
Rise, below middle arteries it is obvious.5~7 centimetres of petiole length, under the outside of belly is slightly concave.Matter is crisp frangible.Gas is faint, and taste is slightly bitter.So that leaf is big, stockless,
The green person of color dull gray is preferred.Main product Jiangsu, Anhui, Hebei, Henan, zhejiang and other places.【Meridian distribution of property and flavor】Bitter, it is cold in nature;Return liver, the heart,
Stomach, the spleen channel.【Function is with curing mainly】It is clearing heat and detoxicating, blood cooling and ecchymoses removing;For pyreticosis hyperpyrexia polydipsia;Coma;Macula;Spit blood;Bleeding from five sense organs or subcutaneous tissue;It is yellow
Subcutaneous ulcer;Rush down dysentery;Erysipelas;Larynx numbness;Aphtha;Mumps.
(7)Coptis root, latin name:Coptis chinensis Franch., alias has taste to connect, river connects, Rhizoma Coptidis, belongs to buttercup
Section, Coptis herbaceos perennial, phyllopodium are hesitated, hard papery, ovate triangle, and three totally cleave, central sliver ovate rhombus, pinniform
There is sharp sawtooth at drastic crack, edge, and life sliver in side does not wait 2 drastic cracks;The long 5-12cm of petiole.It is wild or cultivate in height above sea level 1000-1900m's
In the cool wet concealment thick forest in mountain valley.There is the effect of heat-clearing and damp-drying drug, purging intense heat and detonicating.Its taste entrance is extremely bitter, and having common saying cloud, " mute eats Huang
Even, hardship could not explain ", that is, say wherein flavour.【Meridian distribution of property and flavor】It is pungent, temperature.The thoughts of returning home, lung, kidney channel.【Function is with curing mainly】Heat-clearing
Eliminating dampness, purging intense heat and detonicating.For damp and hot feeling of fullness, acid regurgitation, rush down dysentery, jaundice, unconsciousness due to high fever, heart-fire hyperactivity, dysphoria and insomnia, blood-head are vomitted
Hematemesis, hot eyes, toothache is quenched one's thirst, carbuncle swells furunculosis;Eczema is controlled outside, wet sore, duct is suppurated..
(8)Wu's cornel, English name:Medcinal Evodia Fruit, Fruit of Medicinal Evodia, alias
There are peppery tea, paint spicy, excellent spicy, Koji, gas spicy;3 years after cultivation, early-maturing variety early July, late variety early August, treat
Fruit is harvested when not separated in tea green and carpel, and the whole string fruit ear of harvesting, is sure not to pluck disconnected fruit branch, dries before dew is not dry, is used
Hand is rubbed, and carpopodium is come off, Yang Jing.It is anti-dry with low baking temperature such as the rainy day.【Meridian distribution of property and flavor】It is pungent;It is bitter;Heat;Mild toxicity【Function and master
Control】Coldness and pain in the epigastrium;Jueyin headache;Colic;Tinea pedis swells and ache;Vomit acid regurgitation, cold-dampness diarrhea.
(9)The root of Chinese clematis, latin name:Clematis chinensis Osbeck., alias have gentiana macrophylla, great Ye bark of ash,
RADIX GENTIANAE MACROPHYLLAE;This product is the ranunculaceae plant root of Chinese clematisClematis chinensis Osbeck , Clematis hexapetalaClematis hexapetala Pall. Or northeast clematisClematis manshurica Rupr. Drying root and rhizome.With dispelling
Wind dehumidifies, the effect removed obstruction in channels to relieve pain.For arthralgia pain due to rheumatism, extremity numbness, muscle arteries and veins contraction, joint stuffiness, bone is choked with sobs the diseases such as larynx.
It is distributed in Chinese yunnan south, Guizhou, Sichuan, Southern Shaanxi, Guangxi, Guangdong, Hunan, Hubei, Henan, Fujian, Taiwan, river
West, Zhejiang, South of Jiangsu Province, on the south the Huaihe River of Anhui.Vietnam is also distributed.Give birth in hillside, mountain valley shrubbery or limes marginis, roadside thick grass
In.【Meridian distribution of property and flavor】It is pungent, salty, temperature;Return bladder warp, Liver Channel.【Function is with curing mainly】Dispelling wind and eliminating dampness, removes obstruction in channels to relieve pain;For rheumatism numbness
Bitterly, extremity numbness, muscle arteries and veins contraction, joint stuffiness, bone is choked with sobs larynx.
(10)Excrementum pteropi, latin name:Faeces Trogopterpri, nickname FAECES TROGOPTERORI, how denier, clever fat rice, clever fat rice is
The drying excrement of trogopterus xanthipes Milne-Edwards, clever fat block is that the mixture of its excrement and urine presss from both sides and dries condensation with a small amount of sandstone and form.It can use
In blood-stasis internal-depression, the bleeding of the escape of blood from vessels and channels, such as woman uterine bleeding is through many, color purple polylith, stabbing pain of the lower abdomen.Both can single fry grind, temperature
(medicine) to be taken with wine, can be used cooperatively with other drugs again.Excrementum pteropi is blood-activating and stasis-removing,《Compendium of Materia Medica》Say:" excrementum pteropi ".【Property
Taste channel tropism】It is sweet, temperature.【Function is with curing mainly】Promoting blood circulation to remove blood stasis, fries charcoal hemostasis.For trusted subordinate's extravasated blood, dysmenorrhoea, blood stasis, production
Abdominalgia with blood stasis afterwards;Fry charcoal and control metrostaxis;Traumatic injury, snake, insect bite are controlled in external application.
(11)Rheum officinale, latin name:RheumpalmatumL., nickname general, Huang Liang, fire ginseng, skin such as, another name for Sichuan Province rheum officinale, cow tongue are big
Huang, is that the herbaceos perennial of a variety of polygonaceae Rheums is collectively referred to as, and is typically planted from the rhizome of tubbiness.Rheum officinale is with triangle
Great Ye, petiole is plump.Flower-shape is tiny, is gathered into inflorescence, color is from green white to rose.【Meridian distribution of property and flavor】Hardship, trembles with fear.Stomach
Through;Large intestine channel;Liver Channel;The spleen channel.【Function is with curing mainly】Heat and toxic materials clearing away, clearing heat-fire, removing pattogenic heat from the blood and toxic material from the body, dispelling stasis of blood and stimulating the menstrual flow, removing dampness through diuresis and removing jaundice.
For the stagnant constipation of real heat, blood-head tells nosebleed, hot eyes pharynx swelling, carbuncle swells furunculosis, abdominalgia with intestinal abscess, blood stasis closed, postpartum stasis, bruise is damaged
Wound, damp-heat dysentery, jaundice, stranguria, oedema;Externally treating burns and scalds.Prepared RADIX ET RHIZOMA RHEI with wine is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.For hot eyes pharynx
It is swollen, gingivitis.Prepared RADIX ET RHIZOMA RHEI, which rushes down, exerts oneself to delay, purging intense heat and detonicating.For pathogenic fire,toxin and furuncles.Charred RADIX ET RHIZOMA RHEI cooling blood and removing stasis stops blooding.For blood-head
There is stasis of blood haemorrhage.
(12)Ligusticum wallichii, latin name:Ligusticum chuanxiong Hort., alias have mountain bring up thoroughly, rhizome of chuanxiong Qiong, fragrant fruit, recklessly
Qiong, rhizome of chuanxiong Qiong, sparrow brain rhizome of chuanxiong, capital rhizome of chuanxiong, pass through rhizome of chuanxiong, raw Sichuan troops;Main product is in Sichuan(Guanxian county), on Yunnan, Guizhou, Guangxi and other places, it is grown on
Gentle climatic environment.It is a kind of Chinese medicinal plant, is usually used in blood-activating and qi-promoting, wind-expelling pain-stopping, Ligusticum wallichii pungent-warm perfume (or spice) is dry, walks without keeping,
Can go it is scattered, it is up up to mountain peak top;Enter blood system again, it is descending up to the sea of blood.Promoting blood circulation effect is extensive, and suitable stagnation of blood stasis is various
Illness;Wind-expelling pain-stopping, effectiveness is favourable, can control the diseases such as head wind headache, arthralgia pain due to rheumatism.Former times people meaning Ligusticum wallichii is the gas medicine in blood, dangerous speech
Its function such as pungent scattered, Xie Yu, sensible, analgesic of residing.【Meridian distribution of property and flavor】It is pungent, temperature;Enter liver, gallbladder channel.【Function is with curing mainly】Promote breath and open depression,
Method wind-dryness is wet, promoting blood circulation and stopping pain.Control air-cooled headache rotation dizzy, hypochondriac pain abdomen pain, arthritis muscle contraction, Amenorrhea, difficult labour, postpartum stasis block pain, carbuncle
Subcutaneous ulcer sore.For irregular menstruation, closed dysmenorrhea, lump in the abdomen stomachache, chest side of body shouting pain, tumbling and swelling, headache, arthralgia pain due to rheumatism.
(13)Asarum, latin name:Asarum sieboldii Miq., alias have the careless asarum of asarum sieboldii, basin, it is green must ginger, solely
Leaf grass, beautiful fragrant silk, Jin Pencao;Belong to Aristolochiaceae, herbaceos perennial.For conventional Chinese medicine.《Sheng Nong's herbal classic》It is classified as top grade.
Because its root is thin, pungent, therefore gain the name.【Meridian distribution of property and flavor】It is pungent, temperature.The thoughts of returning home, lung, kidney channel.【Function is with curing mainly】Relieving exterior syndrome and dispelling cold, wind-dispelling stops
Bitterly, it is sensible, Wenfei of drink.For anemofrigid cold, have a headache, toothache, have a stuffy nose runny nose, allergic rhinitis, nasosinusitis, arthralgia pain due to rheumatism, sputum cough.
(14)Centipede, latin name:Scolopendra subspinipes, alias has sky dragon, centipede, Wu Gong;For terrestrial section
Main drive thing, body is made up of many body segments, with step on each section, therefore is biological for polypody.Centipede also known as cry sky dragon, centipede
Worm, Scolopendra subspinipes, Wu Gong, Ji maggot etc., are a kind of venomous, grazing eclipse terrestrial arthropods.Common centipede have reddish tone,
Three kinds of blue or green head, blackhead.The back of reddish tone is in reddish black, and the existing pale red of belly is sufficient for light red orange or yellow.The back of blue or green head and
Foot is in blueness, and belly is light blue, and small, length is about 1/2nd of reddish tone centipede.【Meridian distribution of property and flavor】It is pungent, temperature;It is poisonous.
Return liver warp.【Function is with curing mainly】Ceases wind antispastic, dispersing pathogen accumulation is removed obstruction in channels to relieve pain.For child convulsion, tic spasm, middle air port is askew,
Hemiplegia, lockjaw, rheumatoid arthritis stubborn, sore, scrofula, venomous snake bite.
The pharmacological function of each composition is in the Chinese medicine preparation that the present invention antidotes against snake bite:
The root of Dahurain angelica has wind-dispelling, eliminating dampness, detumescence, analgesic efficacy;There is the Radix Astragali invigorating qi for consolidating superficies, arrest sweating admittedly take off, torr sore myogenic, Li Shui to disappear
Swollen effect;Radix glycyrrhizae have effects that invigorating middle warmer and replenishing QI, relieving spasm to stop pain, moisten the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription;The capsule of weeping forsythia has
Heat-clearing, removing toxic substances, dissipating bind, effect of detumescence;Bulb of thunberg fritillary has effects that clearing heat and eliminating phlegm, sending down abnormally ascending cough-relieving, mass dissipating and swelling eliminating;Folium isatidis has
Clearing heat and detoxicating, blood cooling and ecchymoses removing effect;The coptis has effects that heat-clearing and damp-drying drug, purging intense heat and detonicating;Wu's cornel has warming spleen and stomach for dispelling cold, lower gas
Analgesic, soothing the liver lower gas, effect that eliminating dampness is supporing yang;The root of Chinese clematis has effects that dispelling wind and eliminating dampness, removed obstruction in channels to relieve pain;Excrementum pteropi has promoting blood circulation
Dissipate the stasis of blood, effect of fries charcoal hemostasis;Rheum officinale has heat and toxic materials clearing away, clearing heat-fire, removing pattogenic heat from the blood and toxic material from the body, dispelling stasis of blood and stimulating the menstrual flow, the work(of removing dampness through diuresis and removing jaundice
Effect;Ligusticum wallichii has effects that promote breath and open depression, method wind-dryness be wet, promoting blood circulation and stopping pain;Asarum has relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping, sensible, temperature
Effect of lungization drink;Centipede has effects that ceases wind antispastic, dispersing pathogen accumulation, removed obstruction in channels to relieve pain;Integrate and make use of each taste medicine
Wind-dispelling, eliminating dampness, heat-clearing, detumescence, invigorating qi for consolidating superficies, torr sore myogenic, inducing diuresis for removing edema, invigorating middle warmer and replenishing QI, relieving spasm to stop pain, purging intense heat and detonicating, tune
With all medicines, removing toxic substances, dissipating bind, blood cooling and ecchymoses removing, purging intense heat and detonicating, warming spleen and stomach for dispelling cold, the analgesic of lower gas, eliminating dampness is supporing yang, dispelling wind and eliminating dampness, dredging collateral stop
Bitterly, promoting blood circulation to remove blood stasis, fries charcoal hemostasis, heat and toxic materials clearing away, clearing heat-fire, removing pattogenic heat from the blood and toxic material from the body, dispelling stasis of blood and stimulating the menstrual flow, promote breath and open depression, method wind-dryness are wet, living
Blood and relieving pain, relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping, sensible, Wenfei of drink, ceases wind antispastic, dispersing pathogen accumulation, the effects such as remove obstruction in channels to relieve pain, pass through
The form that for oral administration or for oral administration and external application is embrocated so that the internal organ that the property of medicine penetrates into human body from internal organ or human body skin absorb, then pass through
Blood circulation, dirty into internal organs, so as to eliminate symptom, disease preventing and treating is further aggravated, and reaches the purpose of the effect that antidotes against snake bite.
Compared with the prior art the present invention, be with prominent substantive distinguishing features and significant progress:
1st, the present invention is Chinese medicine preparation, and the herbal nature of each raw material is fully merged, and forms treatment cobra or Bungarus multicinctus snake venom
Specific drug;It can timely and effectively be controlled for snake venom, prevent snake venom for the dirty further destruction of human body internal organs, it is ensured that raw
Life safety;Internal snake venom can be dissolved so that snake venom noresidue;Also there is torr sore myogenic, it is inducing diuresis for removing edema, invigorating middle warmer and replenishing QI, slow
Anxious analgesic, purging intense heat and detonicating, coordinating the drug actions of a prescription, blood cooling and ecchymoses removing, purging intense heat and detonicating, warming spleen and stomach for dispelling cold, lower gas is relieved pain, eliminating dampness is supporing yang, wind-dispelling is removed
It is wet, remove obstruction in channels to relieve pain, promoting blood circulation to remove blood stasis, fries charcoal hemostasis, heat and toxic materials clearing away, dispelling stasis of blood and stimulating the menstrual flow, promote breath and open depression, method wind-dryness are wet, sensible, warm lung
Drink, ceases wind antispastic, dispersing pathogen accumulation, the effects such as remove obstruction in channels to relieve pain;So as to realize the curative effect treated both principal and secondary aspect of disease;Body immune can also be improved
Power,.
2nd, preparation method of the invention is easy to operate, manufacturing process can the maximized property of medicine for retaining each raw material, can be for
Snake venom realizes maximum neutralizing effect, and snake venom is dissolved or discharged in vivo so that snake venom noresidue is in internal, it is ensured that treatment
No sequel, and having no side effect afterwards.
3rd, the present invention can restrain myogenic to wound, promote wound healing, and outer wiping can also be repaired to wound, do not left
Scar.
Embodiment
The following is embodiments of the invention are combined, the present invention is described in detail:
Embodiment 1:
A kind of Chinese medicine preparation antidoted against snake bite, its active ingredient is to be prepared from the following raw materials in parts by weight:
1 part of the root of Dahurain angelica, 1 part of the Radix Astragali, 1 part of radix glycyrrhizae, 1 part of the capsule of weeping forsythia
1 part of bulb of thunberg fritillary, 1 part of folium isatidis, 1 part of coptis root, 1 part of Wu's cornel
1 part of the root of Chinese clematis, 1 part of excrementum pteropi, 1 part of rheum officinale, 1 part of Ligusticum wallichii
1 part of asarum, 0.5 part of centipede.
The preparation method of above-described aqua includes following steps:
(1)By the root of Dahurain angelica, the Radix Astragali, radix glycyrrhizae, folium isatidis, coptis root, the root of Chinese clematis, rheum officinale, Ligusticum wallichii and asarum, impurity elimination is cleaned, drained away the water,
It is put into dryer and is dried, the temperature control in dryer is 70~80 DEG C, it is 10%~12% to be dried to water content, standby;
(2)The capsule of weeping forsythia is weeded out into seed and impurity, drying in dryer is put into, it is standby;
(3)By the net material of bulb of thunberg fritillary, drying in dryer is placed into, it is standby;
(4)By the excrementum pteropi of collection, net material is put into drying in dryer, standby;
(5)Centipede living is collected, net material is stored in vial, standby;
(6)By above-mentioned steps(1)Obtained medicinal material carries out the respective segment of correspondence or section, then extracts each medicine by weight
Material, is well mixed, is put in vial;It is standby;
(7)By weight toward step(6)Step is separately added into the vial of middle gained(2)、(3)With(4)After middle drying
The capsule of weeping forsythia, bulb of thunberg fritillary, excrementum pteropi;It is standby;
(8)By weight toward step(7)Step is added in the vial of middle gained(5)Centipede, then by weight of material add 2
50 DEG C of grain wines again, sealing immersion 15 days, that is, be made the aqua of the Chinese medicine preparation antidoted against snake bite.
The above-described Chinese medicine preparation antidoted against snake bite be prepared in cobra, Bungarus multicinctus snake venom application.
Embodiment 2:
A kind of Chinese medicine preparation antidoted against snake bite, its active ingredient is to be prepared from the following raw materials in parts by weight:
50 parts of the root of Dahurain angelica, 50 parts of the Radix Astragali, 50 parts of radix glycyrrhizae, 50 parts of the capsule of weeping forsythia
50 parts of bulb of thunberg fritillary, 50 parts of folium isatidis, 50 parts of coptis root, 50 parts of Wu's cornel
50 parts of the root of Chinese clematis, 50 parts of excrementum pteropi, 50 parts of rheum officinale, 50 parts of Ligusticum wallichii
50 parts of asarum, 24.75 parts of centipede.
The preparation method of above-described pulvis includes following steps:
(1)By the root of Dahurain angelica, the Radix Astragali, radix glycyrrhizae, the capsule of weeping forsythia, bulb of thunberg fritillary, folium isatidis, coptis root, Wu's cornel, the root of Chinese clematis, rheum officinale, Ligusticum wallichii and asarum, go
It is miscellaneous to clean, drain away the water, be put into dryer and dried, the temperature control in dryer is 70~80 DEG C, is dried to water content
It is standby for 10%~12%;
(2)By the excrementum pteropi of collection, net material is put into drying in dryer, standby;
(3)Centipede living will be collected, net material is put into drying in dryer, removes cephalopodium, standby;
(4)By above-mentioned steps(1)、(2)With(3)In obtained medicinal material carry out correspondence and each chopping or crush, then by weight
Number weighs each medicinal material, sterilizes, and is well mixed, and reuses micronizer and carries out ultramicro grinding;Pack, every bag of 2g is examined, qualified
Product are put in storage, and produce the pulvis of the Chinese medicine preparation antidoted against snake bite.
The above-described Chinese medicine preparation antidoted against snake bite be prepared in cobra, Bungarus multicinctus snake venom application.
Embodiment 3:
A kind of Chinese medicine preparation antidoted against snake bite, its active ingredient is to be prepared from the following raw materials in parts by weight:
100 parts of the root of Dahurain angelica, 100 parts of the Radix Astragali, 100 parts of radix glycyrrhizae, 100 parts of the capsule of weeping forsythia
100 parts of bulb of thunberg fritillary, 100 parts of folium isatidis, 100 parts of coptis root, 100 parts of Wu's cornel
100 parts of the root of Chinese clematis, 100 parts of excrementum pteropi, 100 parts of rheum officinale, 100 parts of Ligusticum wallichii
100 parts of asarum, 50 parts of centipede.
The preparation method of above-described aqua includes following steps:
(1)By the root of Dahurain angelica, the Radix Astragali, radix glycyrrhizae, folium isatidis, coptis root, the root of Chinese clematis, rheum officinale, Ligusticum wallichii and asarum, impurity elimination is cleaned, drained away the water,
It is put into dryer and is dried, the temperature control in dryer is 70~80 DEG C, it is 10%~12% to be dried to water content, standby;
(2)The capsule of weeping forsythia is weeded out into seed and impurity, drying in dryer is put into, it is standby;
(3)By the net material of bulb of thunberg fritillary, drying in dryer is placed into, it is standby;
(4)By the excrementum pteropi of collection, net material is put into drying in dryer, standby;
(5)Centipede living is collected, net material is stored in vial, standby;
(6)By above-mentioned steps(1)Obtained medicinal material carries out the respective segment of correspondence or section, then extracts each medicine by weight
Material, is well mixed, is put in vial;It is standby;
(7)By weight toward step(6)Step is separately added into the vial of middle gained(2)、(3)With(4)After middle drying
The capsule of weeping forsythia, bulb of thunberg fritillary, excrementum pteropi;It is standby;
(8)By weight toward step(7)Step is added in the vial of middle gained(5)Centipede, then by weight of material add 3
52 DEG C of grain wines again, sealing immersion 30 days, that is, be made the aqua of the Chinese medicine preparation antidoted against snake bite.
The above-described Chinese medicine preparation antidoted against snake bite be prepared in cobra, Bungarus multicinctus snake venom application.
Embodiment 4:
A kind of Chinese medicine preparation antidoted against snake bite, its active ingredient is to be prepared from the following raw materials in parts by weight:
52 parts of the root of Dahurain angelica, 48 parts of the Radix Astragali, 48 parts of radix glycyrrhizae, 51 parts of the capsule of weeping forsythia
52 parts of bulb of thunberg fritillary, 55 parts of folium isatidis, 52 parts of coptis root, 54 parts of Wu's cornel
53 parts of the root of Chinese clematis, 54 parts of excrementum pteropi, 55 parts of rheum officinale, 52 parts of Ligusticum wallichii
52 parts of asarum, 25 parts of centipede.
The preparation method of above-described pulvis includes following steps:
(1)By the root of Dahurain angelica, the Radix Astragali, radix glycyrrhizae, the capsule of weeping forsythia, bulb of thunberg fritillary, folium isatidis, coptis root, Wu's cornel, the root of Chinese clematis, rheum officinale, Ligusticum wallichii and asarum, go
It is miscellaneous to clean, drain away the water, be put into dryer and dried, the temperature control in dryer is 70~80 DEG C, is dried to water content
It is standby for 10%~12%;
(2)By the excrementum pteropi of collection, net material is put into drying in dryer, standby;
(3)Centipede living will be collected, net material is put into drying in dryer, removes cephalopodium, standby;
(4)By above-mentioned steps(1)、(2)With(3)In obtained medicinal material carry out correspondence and each chopping or crush, then by weight
Number weighs each medicinal material, sterilizes, and is well mixed, and reuses micronizer and carries out ultramicro grinding;Pack, every bag of 2g is examined, qualified
Product are put in storage, and produce the pulvis of the Chinese medicine preparation antidoted against snake bite.
The above-described Chinese medicine preparation antidoted against snake bite be prepared in cobra, Bungarus multicinctus snake venom application.
Embodiment 5:
A kind of Chinese medicine preparation antidoted against snake bite, its active ingredient is to be prepared from the following raw materials in parts by weight:
60 parts of the root of Dahurain angelica, 60 parts of the Radix Astragali, 60 parts of radix glycyrrhizae, 62 parts of the capsule of weeping forsythia
62 parts of bulb of thunberg fritillary, 62 parts of folium isatidis, 60 parts of coptis root, 60 parts of Wu's cornel
60 parts of the root of Chinese clematis, 60 parts of excrementum pteropi, 60 parts of rheum officinale, 62 parts of Ligusticum wallichii
62 parts of asarum, 31 parts of centipede.
The preparation method of above-described aqua includes following steps:
(1)By the root of Dahurain angelica, the Radix Astragali, radix glycyrrhizae, folium isatidis, coptis root, the root of Chinese clematis, rheum officinale, Ligusticum wallichii and asarum, impurity elimination is cleaned, drained away the water,
It is put into dryer and is dried, the temperature control in dryer is 70~80 DEG C, it is 10%~12% to be dried to water content, standby;
(2)The capsule of weeping forsythia is weeded out into seed and impurity, drying in dryer is put into, it is standby;
(3)By the net material of bulb of thunberg fritillary, drying in dryer is placed into, it is standby;
(4)By the excrementum pteropi of collection, net material is put into drying in dryer, standby;
(5)Centipede living is collected, net material is stored in vial, standby;
(6)By above-mentioned steps(1)Obtained medicinal material carries out the respective segment of correspondence or section, then extracts each medicine by weight
Material, is well mixed, is put in vial;It is standby;
(7)By weight toward step(6)Step is separately added into the vial of middle gained(2)、(3)With(4)After middle drying
The capsule of weeping forsythia, bulb of thunberg fritillary, excrementum pteropi;It is standby;
(8)By weight toward step(7)Step is added in the vial of middle gained(5)Centipede, then by weight of material add 5
55 DEG C of grain wines again, sealing immersion 45 days, that is, be made the aqua of the Chinese medicine preparation antidoted against snake bite.
The above-described Chinese medicine preparation antidoted against snake bite be prepared in cobra, Bungarus multicinctus snake venom application.
Embodiment 6:
A kind of Chinese medicine preparation antidoted against snake bite, its active ingredient is to be prepared from the following raw materials in parts by weight:
24 parts of the root of Dahurain angelica, 24 parts of the Radix Astragali, 24 parts of radix glycyrrhizae, 22 parts of the capsule of weeping forsythia
24 parts of bulb of thunberg fritillary, 24 parts of folium isatidis, 24 parts of coptis root, 22 parts of Wu's cornel
22 parts of the root of Chinese clematis, 24 parts of excrementum pteropi, 24 parts of rheum officinale, 24 parts of Ligusticum wallichii
22 parts of asarum, 12 parts of centipede.
The preparation method of above-described pulvis includes following steps:
(1)By the root of Dahurain angelica, the Radix Astragali, radix glycyrrhizae, the capsule of weeping forsythia, bulb of thunberg fritillary, folium isatidis, coptis root, Wu's cornel, the root of Chinese clematis, rheum officinale, Ligusticum wallichii and asarum, go
It is miscellaneous to clean, drain away the water, be put into dryer and dried, the temperature control in dryer is 70~80 DEG C, is dried to water content
It is standby for 10%~12%;
(2)By the excrementum pteropi of collection, net material is put into drying in dryer, standby;
(3)Centipede living will be collected, net material is put into drying in dryer, removes cephalopodium, standby;
(4)By above-mentioned steps(1)、(2)With(3)In obtained medicinal material carry out correspondence and each chopping or crush, then by weight
Number weighs each medicinal material, sterilizes, and is well mixed, and reuses micronizer and carries out ultramicro grinding;Pack, every bag of 2g is examined, qualified
Product are put in storage, and produce the pulvis of the Chinese medicine preparation antidoted against snake bite.
The above-described Chinese medicine preparation antidoted against snake bite be prepared in cobra, Bungarus multicinctus snake venom application.
Embodiment 7:
A kind of Chinese medicine preparation antidoted against snake bite, its active ingredient is to be prepared from the following raw materials in parts by weight:
36 parts of the root of Dahurain angelica, 36 parts of the Radix Astragali, 36 parts of radix glycyrrhizae, 34 parts of the capsule of weeping forsythia
34 parts of bulb of thunberg fritillary, 34 parts of folium isatidis, 33 parts of coptis root, 33 parts of Wu's cornel
34 parts of the root of Chinese clematis, 32 parts of excrementum pteropi, 33 parts of rheum officinale, 34 parts of Ligusticum wallichii
32 parts of asarum, 16 parts of centipede.
The preparation method of above-described aqua includes following steps:
(1)By the root of Dahurain angelica, the Radix Astragali, radix glycyrrhizae, folium isatidis, coptis root, the root of Chinese clematis, rheum officinale, Ligusticum wallichii and asarum, impurity elimination is cleaned, drained away the water,
It is put into dryer and is dried, the temperature control in dryer is 70~80 DEG C, it is 10%~12% to be dried to water content, standby;
(2)The capsule of weeping forsythia is weeded out into seed and impurity, drying in dryer is put into, it is standby;
(3)By the net material of bulb of thunberg fritillary, drying in dryer is placed into, it is standby;
(4)By the excrementum pteropi of collection, net material is put into drying in dryer, standby;
(5)Centipede living is collected, net material is stored in vial, standby;
(6)By above-mentioned steps(1)Obtained medicinal material carries out the respective segment of correspondence or section, then extracts each medicine by weight
Material, is well mixed, is put in vial;It is standby;
(7)By weight toward step(6)Step is separately added into the vial of middle gained(2)、(3)With(4)After middle drying
The capsule of weeping forsythia, bulb of thunberg fritillary, excrementum pteropi;It is standby;
(8)By weight toward step(7)Step is added in the vial of middle gained(5)Centipede, then by weight of material add 4
54 DEG C of grain wines again, sealing immersion 35 days, that is, be made the aqua of the Chinese medicine preparation antidoted against snake bite.
The above-described Chinese medicine preparation antidoted against snake bite be prepared in cobra, Bungarus multicinctus snake venom application.
Embodiment 8:
A kind of Chinese medicine preparation antidoted against snake bite, its active ingredient is to be prepared from the following raw materials in parts by weight:
45 parts of the root of Dahurain angelica, 45 parts of the Radix Astragali, 46 parts of radix glycyrrhizae, 48 parts of the capsule of weeping forsythia
46 parts of bulb of thunberg fritillary, 45 parts of folium isatidis, 48 parts of coptis root, 44 parts of Wu's cornel
44 parts of the root of Chinese clematis, 46 parts of excrementum pteropi, 48 parts of rheum officinale, 46 parts of Ligusticum wallichii
46 parts of asarum, 22 parts of centipede.
The preparation method of above-described pulvis includes following steps:
(1)By the root of Dahurain angelica, the Radix Astragali, radix glycyrrhizae, the capsule of weeping forsythia, bulb of thunberg fritillary, folium isatidis, coptis root, Wu's cornel, the root of Chinese clematis, rheum officinale, Ligusticum wallichii and asarum, go
It is miscellaneous to clean, drain away the water, be put into dryer and dried, the temperature control in dryer is 70~80 DEG C, is dried to water content
It is standby for 10%~12%;
(2)By the excrementum pteropi of collection, net material is put into drying in dryer, standby;
(3)Centipede living will be collected, net material is put into drying in dryer, removes cephalopodium, standby;
(4)By above-mentioned steps(1)、(2)With(3)In obtained medicinal material carry out correspondence and each chopping or crush, then by weight
Number weighs each medicinal material, sterilizes, and is well mixed, and reuses micronizer and carries out ultramicro grinding;Pack, every bag of 2g is examined, qualified
Product are put in storage, and produce the pulvis of the Chinese medicine preparation antidoted against snake bite.
The above-described Chinese medicine preparation antidoted against snake bite be prepared in cobra, Bungarus multicinctus snake venom application.
The present invention pulvis application method be:
Bite by Naja naja atra is directed to, treatment method is:
(1)The poison that goes out is carried out to wound;I.e. with the potassium permanganate dilution that normal saline dilution potassium permanganate is 0.1%, in wound
Place, the potassium permanganate dilution of injection 0.1% is gone out poison, and injection volume can be carried out according to wound situation;
(2)Using 20~30 DEG C of the white wine modulation of the pulvis of the present invention, often bag pulvis 5ml, then orally, three times a day;Directly
To poisoning symptom is eliminated, the state of an illness is fully recovered.Or oral while, can by pulvis using white wine modulation after, outer wiping whole body reaches
Effect of internal and external treatment.
Induced By Coral Snake Bite is directed to, treatment method is:
(1)The poison that goes out is carried out to wound;I.e. with the potassium permanganate dilution that normal saline dilution potassium permanganate is 0.1%, in wound
Place, the potassium permanganate dilution of injection 0.1% is gone out poison, and injection volume can be carried out according to wound situation;
(2)Using the light-coloured vinegar modulation of the pulvis of the present invention, often bag pulvis 5ml, then orally, three times a day;Until poisoning symptom
Eliminate, state of an illness recovery from illness.Or oral while, can by pulvis using light-coloured vinegar modulation after, outer wiping whole body reaches internal and external treatment
Effect.
The present invention aqua application method be:
Bite by Naja naja atra is directed to, treatment method is:
(1)The poison that goes out is carried out to wound;I.e. with the potassium permanganate dilution that normal saline dilution potassium permanganate is 0.1%, in wound
Place, the potassium permanganate dilution of injection 0.1% is gone out poison, and injection volume can be carried out according to wound situation;
(2)Take 20~40ml of aqua of the present invention orally, three times a day;Until poisoning symptom is eliminated, state of an illness recovery from illness.Or oral
Meanwhile, aqua can be used, outer wiping whole body reaches effect of internal and external treatment.
Induced By Coral Snake Bite is directed to, treatment method is:
(1)The poison that goes out is carried out to wound;I.e. with the potassium permanganate dilution that normal saline dilution potassium permanganate is 0.1%, in wound
Place, the potassium permanganate dilution of injection 0.1% is gone out poison, and injection volume can be carried out according to wound situation;
(2)Take 20~40ml of aqua of the present invention orally, three times a day;Until poisoning symptom is eliminated, state of an illness recovery from illness.Or oral
Meanwhile, aqua can be used, outer wiping whole body reaches effect of internal and external treatment.
Above-described embodiment using effect
Start within -2016 years 2011 the Chinese medicine preparation that the present invention on probation antidotes against snake bite, the wherein people of volunteer 30, glasses in Hengxian County
The people of patient 30 of snake bite, the people of patient 30 of Induced By Coral Snake Bite.
Feeling dizzy occurs in the wounded of bite by Naja naja atra, eye-blurred, vomiting, salivation, uncomfortable in chest, expiratory dyspnea, serious
Patient there is also the symptoms such as language problem, the respiratory paralysis of periphery property, weakness of limbs or total paralysis, around dental impression and suffer from
Person has obvious swelling, there is ecchymosis, bubble and bleeding blister, necrosis and ulcer etc..
Feeling dizzy occurs in the wounded of Induced By Coral Snake Bite, limbs fatigue, muscle, arthralgia, uncomfortable in chest, gas then occurs
Rush, Nausea and vomiting, stomachache;Occur dysphagia, mydriasis, whole-body muscle paralysis when serious quickly, cause respiratory muscle fiber crops
The symptoms such as numbness, heart arrest.
Patient uses the Chinese medicine preparation that antidotes against snake bite of the present invention for oral administration or outer wiping for oral administration, and 3 times a day, and general 1-2 days take effect, 2-
Turn for the better by and large within 3 days, basic rehabilitation in 7-15 days, effective percentage reaches more than 96%.
The Chinese medicine preparation that the present invention antidotes against snake bite was treated to 60 cases altogether from 2011 to 2016, the effect for the treatment of
Such as following table:
Table 1 is the efficacy result of bite by Naja naja atra
Group name | Treatment number | Cure | It is invalid | Total effective rate |
Treatment group | 30 | 29 | 1 | 96% |
Pass through table 1, it is seen that the present invention for bite by Naja naja atra treated effect up to more than 96%.
Table 2 is the efficacy result of Induced By Coral Snake Bite
Group name | Treatment number | Cure | It is invalid | Total effective rate |
Treatment group | 30 | 29 | 1 | 96% |
Pass through table 2, it is seen that the present invention for Induced By Coral Snake Bite treated effect up to more than 96%.
Remarks:It is unobvious to the state of an illness in using the present invention 30 minutes for cobra or the patient of Induced By Coral Snake Bite
Control action, is please rushed to hospital in time.
Clinical practice embodiment:
Case 1
Business XX, man, 16 years old, Guangxi Zhuang Autonomous Region people from Heng County followed father and mother to the Jasmine field weeding of oneself, weeding
Journey, feels that left foot has a hypodynia suddenly, but does not take notice of, suddenly, and scurry out a cobra on side, it is flurried in cobra is beaten
Extremely, do not find oneself, by venomous snake bite, to continue to work yet, it is excessively general 10 minutes, feel that left foot is numb, whole body heating is checked
Left foot, finds two teeth marks, just recognizes oneself by bite by Naja naja atra, and he is carried go home in a hurry by father and mother, and the poison that goes out is carried out to wound;
I.e. with the potassium permanganate dilution that normal saline dilution potassium permanganate is 0.1%, in wound, the potassium permanganate of injection 0.1% is dilute
Release liquid to go out after poison, the pulvis of the embodiment of the present invention 2 is modulated with 25 DEG C of white wine, at once for oral administration, after 30 minutes, symptom is obtained substantially
Alleviate, occur oedema during 1 to 3 day, but be all effectively controlled by taking the pulvis of the present invention, continue to take the present invention's
Pulvis, after 10 days, state of an illness recovery from illness, and do not leave scar.
Case 2
Lee XX, man, 25 years old, Guangxi Zhuang Autonomous Region people from Heng County was lumberman, to help people to cut down eucalyptus as industry;Often on mountain
Worked on mound, positive cut using chain saw flies the snake that scurries out on trees, right-hand side, hide too late, the right hand is directly bitten by snake, lost
Lower chain saw, left hand pinches the neck of snake, and snake is carefully recognized, is the discovery that poisonous snake cobra, and after snake is handled, skin is used at once
Band tightens right hand arm, is caught up with once toward family, on the way home, and oedema nigrescence, eye-blurred, vomiting, expiratory dyspnea occurs in arm;
Go back home, at once using with the potassium permanganate dilution that normal saline dilution potassium permanganate is 0.1%, in wound, injection
0.1% potassium permanganate dilution is gone out after poison, the aqua of the oral embodiment of the present invention 1, and wound location is wiped with aqua
Wipe, after 20 minutes, can be clearly felt that poisoning symptom is controlled, eyesight is apparent from, vomit, have difficulty in breathing it is larger mitigate;
Unstrap, after 2 days, obvious mitigation has occurred in oedema, and wound location, which is also occurred without, festers;Continue to take and wipe after 10 days,
The state of an illness is fully recovered, and arm recovers normal, and the wound location colour of skin is normal, does not leave scar.
Case 3
Deep XX, female, 60 years old, Guangxi Zhuang Autonomous Region people from Heng County inhabited at the foot of the hill, found from family chicken speechless without reason in the dust two or three
Only, suspection is imprudence when spreading rat poison, is spread to chicken coop, just picks up besom and enter to be cleaned, sweeps process, unexpected eye
Before fly a black thing of scurrying out, hit the right leg of oneself, and feel pain, besom subconsciousness is hit towards black thing, is directly killed,
Take out and give household's identification, just know it is Bungarus multicinctus, household helps her the use of use normal saline dilution potassium permanganate to be 0.1% at once
Potassium permanganate dilution, in wound, the potassium permanganate dilution of injection 0.1% is gone out after poison, and the present invention is modulated with 20 DEG C of white wine
The pulvis of embodiment 4, it is at once for oral administration, meanwhile, pulvis and white wine are modulated into volume, wiping whole body is carried out;After 3 hours, occur light
Micro- vomiting, but breathe smooth;Take after second, the state of an illness is effectively controlled, and continues to take after 3 days, state of an illness recovery from illness recovers
Normally.
Case 4
Old XX, man, 40 years old, Guangxi Zhuang Autonomous Region people from Heng County, evening poured water to oneself rice terrace, and weeds are more on ridge, walked
When, hard thing of stepping on, left foot has the pain stung as leech, is shone with flashlight one, is the discovery that a Bungarus multicinctus, lose no time tripping, checks
Left foot, discovery has two red points, and has feeling of numbness, and using the rope carried with, left foot is tightened, goes home to have used
Normal saline dilution potassium permanganate is 0.1% potassium permanganate dilution, in wound, the potassium permanganate dilution of injection 0.1%
Go out after poison, take the aqua of the embodiment of the present invention 3, after 1 hour, a small amount of oedema occurs in wound location, other to all go well, and does not have
There is the symptom being poisoned, the state of an illness is fully recovered after 3 days.
Case 5
Sieve XX, female, 30 years old, Guangxi Zhuang Autonomous Region people from Heng County, by bite by Naja naja atra in the right hand, in hospitalize, still, wound
Position occurs festering, it is necessary to perform an operation, and costly, selection is abandoned going home, upon somebody's introduction the Chinese medicine preparation that antidotes against snake bite of the invention;
In wound, the potassium permanganate dilution of injection 0.1% is gone out after poison, and the pulvis of the embodiment of the present invention 6 is modulated with 20 DEG C of white wine,
Carry out orally, meanwhile, wound is wiped, after 3 days, symptom of festering is effectively controlled, without purulence, occurs new skin after 5 days,
After 10 days, wound scabs, and scar comes off after 12 days, and obvious scar is not left in wound.
Claims (5)
1. a kind of Chinese medicine preparation antidoted against snake bite, it is characterised in that:Its active ingredient is to be prepared from the following raw materials in parts by weight:
1~100 part of the root of Dahurain angelica, 1~100 part of the Radix Astragali, 1~100 part of radix glycyrrhizae, 1~100 part of the capsule of weeping forsythia
1~100 part of bulb of thunberg fritillary, 1~100 part of folium isatidis, 1~100 part of coptis root, 1~100 part of Wu's cornel
1~100 part of the root of Chinese clematis, 1~100 part of excrementum pteropi, 1~100 part of rheum officinale, 1~100 part of Ligusticum wallichii
1~100 part of asarum, 0.5~50 part of centipede.
2. the Chinese medicine preparation according to claim 1 antidoted against snake bite, it is characterised in that:Described Chinese medicine preparation is aqua or powder
Agent.
3. the Chinese medicine preparation according to claim 2 antidoted against snake bite, it is characterised in that the preparation method of described aqua includes
Following steps:
(1)By the root of Dahurain angelica, the Radix Astragali, radix glycyrrhizae, folium isatidis, coptis root, the root of Chinese clematis, rheum officinale, Ligusticum wallichii and asarum, impurity elimination is cleaned, drained away the water,
It is put into dryer and is dried, the temperature control in dryer is 70~80 DEG C, it is 10%~12% to be dried to water content, standby;
(2)The capsule of weeping forsythia is weeded out into seed and impurity, drying in dryer is put into, it is standby;
(3)By the net material of bulb of thunberg fritillary, drying in dryer is placed into, it is standby;
(4)By the excrementum pteropi of collection, net material is put into drying in dryer, standby;
(5)Centipede living is collected, net material is stored in vial, standby;
(6)By above-mentioned steps(1)Obtained medicinal material carries out the respective segment of correspondence or section, then extracts each medicine by weight
Material, is well mixed, is put in vial;It is standby;
(7)By weight toward step(6)Step is separately added into the vial of middle gained(2)、(3)With(4)After middle drying
The capsule of weeping forsythia, bulb of thunberg fritillary, excrementum pteropi;It is standby;
(8)By weight toward step(7)Step is added in the vial of middle gained(5)Centipede, then by weight of material add 2
50 DEG C of~5 times~55 DEG C of grain wines, sealing immersion 15~45 days, that is, be made the aqua of the Chinese medicine preparation antidoted against snake bite.
4. the Chinese medicine preparation according to claim 2 antidoted against snake bite, it is characterised in that the preparation method of described pulvis includes
Following steps:
(1)By the root of Dahurain angelica, the Radix Astragali, radix glycyrrhizae, the capsule of weeping forsythia, bulb of thunberg fritillary, folium isatidis, coptis root, Wu's cornel, the root of Chinese clematis, rheum officinale, Ligusticum wallichii and asarum, go
It is miscellaneous to clean, drain away the water, be put into dryer and dried, the temperature control in dryer is 70~80 DEG C, is dried to water content
It is standby for 10%~12%;
(2)By the excrementum pteropi of collection, net material is put into drying in dryer, standby;
(3)Centipede living will be collected, net material is put into drying in dryer, removes cephalopodium, standby;
(4)By above-mentioned steps(1)、(2)、(3)In obtained medicinal material carry out correspondence and each chopping or crush, then by weight
Each medicinal material is weighed, is sterilized, is well mixed, micronizer is reused and carries out ultramicro grinding;Pack, every bag of 2g is examined, certified products
Storage, produces the pulvis of the Chinese medicine preparation antidoted against snake bite.
5. the Chinese medicine preparation according to claim 1 antidoted against snake bite be prepared in cobra, Bungarus multicinctus snake venom application.
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101108221A (en) * | 2006-07-20 | 2008-01-23 | 杨荣刚 | Extensive antitoxin medicine for treating various snakebite |
CN104721484A (en) * | 2015-04-03 | 2015-06-24 | 吴明国 | Traditional Chinese medicine composition for treating venomous snake bites |
CN106038961A (en) * | 2016-06-25 | 2016-10-26 | 三江县连兴蛇业有限公司 | Traditional Chinese medicinal composition for treating cobra bite |
-
2017
- 2017-05-04 CN CN201710308344.2A patent/CN107050275A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101108221A (en) * | 2006-07-20 | 2008-01-23 | 杨荣刚 | Extensive antitoxin medicine for treating various snakebite |
CN104721484A (en) * | 2015-04-03 | 2015-06-24 | 吴明国 | Traditional Chinese medicine composition for treating venomous snake bites |
CN106038961A (en) * | 2016-06-25 | 2016-10-26 | 三江县连兴蛇业有限公司 | Traditional Chinese medicinal composition for treating cobra bite |
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Application publication date: 20170818 |