CN107050108A - Daybreak pellet drop pills and preparation method thereof - Google Patents
Daybreak pellet drop pills and preparation method thereof Download PDFInfo
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- CN107050108A CN107050108A CN201710471970.3A CN201710471970A CN107050108A CN 107050108 A CN107050108 A CN 107050108A CN 201710471970 A CN201710471970 A CN 201710471970A CN 107050108 A CN107050108 A CN 107050108A
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- 239000006187 pill Substances 0.000 title claims abstract description 37
- 238000002360 preparation method Methods 0.000 title claims abstract description 8
- 239000008188 pellet Substances 0.000 title description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 29
- 239000003814 drug Substances 0.000 claims abstract description 14
- 244000037364 Cinnamomum aromaticum Species 0.000 claims abstract description 10
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims abstract description 10
- 240000008397 Ganoderma lucidum Species 0.000 claims abstract description 10
- 235000001637 Ganoderma lucidum Nutrition 0.000 claims abstract description 10
- 241001165494 Rhodiola Species 0.000 claims abstract description 10
- 240000007164 Salvia officinalis Species 0.000 claims abstract description 10
- 235000005412 red sage Nutrition 0.000 claims abstract description 10
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims abstract description 9
- 229960003511 macrogol Drugs 0.000 claims abstract description 9
- 239000006071 cream Substances 0.000 claims abstract description 8
- 238000000605 extraction Methods 0.000 claims abstract description 7
- 208000024172 Cardiovascular disease Diseases 0.000 claims abstract 2
- 208000026106 cerebrovascular disease Diseases 0.000 claims abstract 2
- 230000002526 effect on cardiovascular system Effects 0.000 claims abstract 2
- 239000000284 extract Substances 0.000 claims description 32
- 238000009833 condensation Methods 0.000 claims description 7
- 230000005494 condensation Effects 0.000 claims description 7
- 238000001035 drying Methods 0.000 claims description 7
- 239000000706 filtrate Substances 0.000 claims description 7
- 239000000843 powder Substances 0.000 claims description 7
- 238000007493 shaping process Methods 0.000 claims description 7
- 238000001694 spray drying Methods 0.000 claims description 7
- 239000002826 coolant Substances 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 6
- 238000010992 reflux Methods 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims 2
- 239000004575 stone Substances 0.000 claims 1
- 206010020772 Hypertension Diseases 0.000 abstract description 7
- 208000029078 coronary artery disease Diseases 0.000 abstract description 7
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract description 4
- 229940079593 drug Drugs 0.000 abstract description 2
- 239000007921 spray Substances 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 description 18
- 208000024891 symptom Diseases 0.000 description 13
- 238000011282 treatment Methods 0.000 description 12
- 230000001225 therapeutic effect Effects 0.000 description 7
- 206010008190 Cerebrovascular accident Diseases 0.000 description 6
- 208000006011 Stroke Diseases 0.000 description 6
- 238000011835 investigation Methods 0.000 description 6
- 230000000694 effects Effects 0.000 description 5
- 201000005577 familial hyperlipidemia Diseases 0.000 description 5
- 150000001875 compounds Chemical class 0.000 description 3
- 230000008034 disappearance Effects 0.000 description 3
- 230000002349 favourable effect Effects 0.000 description 3
- 230000010354 integration Effects 0.000 description 3
- 239000002994 raw material Substances 0.000 description 2
- WTPPRJKFRFIQKT-UHFFFAOYSA-N 1,6-dimethyl-8,9-dihydronaphtho[1,2-g][1]benzofuran-10,11-dione;1-methyl-6-methylidene-8,9-dihydro-7h-naphtho[1,2-g][1]benzofuran-10,11-dione Chemical compound O=C1C(=O)C2=C3CCCC(=C)C3=CC=C2C2=C1C(C)=CO2.O=C1C(=O)C2=C3CCC=C(C)C3=CC=C2C2=C1C(C)=CO2 WTPPRJKFRFIQKT-UHFFFAOYSA-N 0.000 description 1
- 244000131316 Panax pseudoginseng Species 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 239000009524 danshen dripping Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 208000028867 ischemia Diseases 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 244000132619 red sage Species 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/41—Crassulaceae (Stonecrop family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/074—Ganoderma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
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Abstract
The invention discloses red drop pills of a kind of Chinese medicine daybreak for treating cardiovascular and cerebrovascular diseases and preparation method thereof, it is characterized in that rhodiola root, cassia seed, the red sage root, ganoderma lucidum prescription are used into extraction process by water, it is concentrated in vacuo, is spray dried to dry cream, plus Macrogol 6000 is mixed, instill in atoleine, the red drop pills of daybreak are made, for treating hyperlipidemia, hypertension, coronary heart disease, it is evident in efficacy to be better than similar marketed drugs, achieve good result.
Description
Technical field
The present invention relates to the field of Chinese medicines, and in particular to red drop pills of a kind of daybreak and preparation method thereof.
Background technology
Hyperlipemia, hypertension, Incidence of CHD are high, have a strong impact on the quality of life of people.I using rhodiola root,
Cassia seed, the red sage root, ganoderma lucidum prescription therapeutic hyperlipemia, high blood pressure, coronary heart disease for many years, obtain good result, evident in efficacy excellent
In similar commercially available medicine.
The content of the invention
The present invention be according to my tcm clinical practice experience for many years, it is red there is provided a kind of daybreak with reference to modern Chinese herbal medicine preparation technique
Drop pills and preparation method thereof.
Invention embodiment is as follows：
100~300 parts of rhodiola root is taken, 100~300 parts of cassia seed, 100~300 parts of the red sage root, 100~300 parts of ganoderma lucidum adds water back
Stream is extracted three times, is added water 10 times and is measured for the first time, is extracted 3 hours, is added water 8 times and measure for the second time, is extracted 2 hours, is added water for the third time 8 times
Amount, is extracted 2 hours, merging filtrate, is concentrated in vacuo, and spray drying gets dry extract, crushed 100 mesh sieves, get dry extract powder；Take dry cream
Plus 2 times of amount Macrogol 6000s are mixed, 65~75 DEG C of control material temperature, 2~10 DEG C of condensation temperature is dripped away from 2.0~4.0 ㎝,
Drop speed 20~40 drop per minute, instills in atoleine, is taken out after dripping pill shaping, suck surface coolant, be drying to obtain, be made
Daybreak pellet drop pills.
The raw material standards that the embodiment above is previously mentioned is as follows：
Rhodiola root：The Chinese Pharmacopoeia ministerial standard of version one in 2015；
Cassia seed：The Chinese Pharmacopoeia ministerial standard of version one in 2015；
The red sage root：The Chinese Pharmacopoeia ministerial standard of version one in 2015；
Ganoderma lucidum：The Chinese Pharmacopoeia ministerial standard of version one in 2015；
Macrogol 6000：The Chinese Pharmacopoeia ministerial standard of version two in 2015.
Atoleine：The Chinese Pharmacopoeia ministerial standard of version two in 2015.
Raw material used in above daybreak pellet drop pills can be commercially available from pharmaceuticals, as long as meeting national standard
It can be used to implement the present invention program.
Term in embodiments above, the guideline all promulgated with Chinese Pharmacopoeia and State Food and Drug Administration
Explanation is defined.
" part " finger parts by weight in implementing above.
Four embodiments
The specific embodiment 1 of the present invention
Rhodiola root 100g, cassia seed 100g, red sage root 100g, ganoderma lucidum 100g are taken, the refluxing extraction that adds water three times adds water 10 times for the first time
Amount, extracts 3 hours, adds water 8 times and measure for the second time, extracts 2 hours, adds water 8 times and measure for the third time, extracts 2 hours, merging filtrate, very
Sky concentration, spray drying gets dry extract, crushed 100 mesh sieves, get dry extract powder；Dry cream plus 2 times of amount Macrogol 6000s are taken to mix,
65 DEG C of control material temperature, 4 DEG C of condensation temperature, drop is away from 2.0~4.0 ㎝, and drop speed 20 drop per minute is instilled in atoleine, drop
Taken out after ball shaping, suck surface coolant, be drying to obtain, the red drop pills of daybreak are made.
The specific embodiment 2 of the present invention
Rhodiola root 300g, cassia seed 300g, red sage root 300g, ganoderma lucidum 300g are taken, the refluxing extraction that adds water three times adds water 10 times for the first time
Amount, extracts 3 hours, adds water 8 times and measure for the second time, extracts 2 hours, adds water 8 times and measure for the third time, extracts 2 hours, merging filtrate, very
Sky concentration, spray drying gets dry extract, crushed 100 mesh sieves, get dry extract powder；Dry cream plus 2 times of amount Macrogol 6000s are taken to mix,
75 DEG C of control material temperature, 8 DEG C of condensation temperature, drop is away from 2.0~4.0 ㎝, and drop speed 30 drop per minute is instilled in atoleine, drop
Taken out after ball shaping, suck surface coolant, be drying to obtain, the red drop pills of daybreak are made.
The specific embodiment 3 of the present invention
Rhodiola root 200g, cassia seed 200g, red sage root 200g, ganoderma lucidum 200g are taken, the refluxing extraction that adds water three times adds water 10 times for the first time
Amount, extracts 3 hours, adds water 8 times and measure for the second time, extracts 2 hours, adds water 8 times and measure for the third time, extracts 2 hours, merging filtrate, very
Sky concentration, spray drying gets dry extract, crushed 100 mesh sieves, get dry extract powder；Dry cream plus 2 times of amount Macrogol 6000s are taken to mix,
Control material temperature 70 C, 4 DEG C of condensation temperature, drop is away from 2.0~4.0 ㎝, and drop speed 25 drop per minute is instilled in atoleine, drop
Taken out after ball shaping, suck surface coolant, be drying to obtain, the red drop pills of daybreak are made.
Above example illustrates, the red spirit of daybreak can be made using the extreme condition and optimal conditions of embodiment of the present invention
Dripping pill.The actual effect of the present invention is investigated with daybreak pellet drop pills made from embodiment 3 below：
（One）Daybreak pellet drop pills treatment hyperlipidemia clinical observation on the therapeutic effect
1 case scenario
Outpatient service and inpatient are counted, hyperlipidemia case 60, average age 37 years old are observed altogether.Patient is treated by new Chinese medicine
Apoplexy guideline of clinical investigations TCM syndrome diagnostic criteria is diagnosed as hyperlipidemia.Patient is randomly divided into two groups, experiment
Group takes the red drop pills of daybreak, and control group takes tablets for treating hyperlipemia.
2 efficacy assessment standards
Apoplexy guideline of clinical investigations tcm syndrome curative effect determinate standard is treated according to new Chinese medicine：
Cure：Tcm clinical practice symptom, sign disappear or basic disappearance, and syndrome integral reduces >=95%.
It is effective：Tcm clinical practice symptom, sign are obviously improved, and syndrome integral reduces >=70%.
Effectively：Tcm clinical practice symptom, sign take a favorable turn, and syndrome integral reduces >=30%.
It is invalid：Tcm clinical practice symptom, sign are not improved or aggravated, and syndrome integral reduces ＜ 30%.
Calculation formula：[（Integrated before treatment after integration-treatment）Integrated before ÷ treatments] × 100%.
3 clinical observation results
The daybreak of table 1 pellet drop pills and tablets for treating hyperlipemia clinical efficacy contrast table
Above-mentioned clinical observation on the therapeutic effect result shows, when the red drop pills of daybreak prepared by the present invention treat ischemia apoplexy, curative effect
It is significantly higher than tablets for treating hyperlipemia, p ＜ 0.01.
（Two）Daybreak pellet drop pills treatment hypertension clinical observation on the therapeutic effect
1 case scenario
Outpatient service and inpatient are counted, hypertension 80 cases, average age 45 years old are observed altogether.Patient is by new Chinese medicine treatment
Wind disease guideline of clinical investigations TCM syndrome diagnostic criteria is diagnosed as hypertension.Patient is randomly divided into two groups, test group clothes
With the red drop pills of daybreak, control group takes Qingnao Jiangyapian.
2 efficacy assessment standards
Apoplexy guideline of clinical investigations tcm syndrome curative effect determinate standard is treated according to new Chinese medicine：
Cure：Tcm clinical practice symptom, sign disappear or basic disappearance, and syndrome integral reduces >=95%.
It is effective：Tcm clinical practice symptom, sign are obviously improved, and syndrome integral reduces >=70%.
Effectively：Tcm clinical practice symptom, sign take a favorable turn, and syndrome integral reduces >=30%.
It is invalid：Tcm clinical practice symptom, sign are not improved or aggravated, and syndrome integral reduces ＜ 30%.
Calculation formula：[（Integrated before treatment after integration-treatment）Integrated before ÷ treatments] × 100%.
3 clinical observation results
The daybreak of table 2 pellet drop pills and Qingnao Jiangyapian clinical efficacy contrast table
Above-mentioned clinical observation on the therapeutic effect result shows, when the red drop pills of daybreak prepared by the present invention treat hypertension, height evident in efficacy
In Qingnao Jiangyapian, p ＜ 0.05.
（Three）Daybreak pellet drop pills control coronary heart disease clinical observation on the therapeutic effect
1 case scenario
Outpatient service and inpatient are counted, coronary heart disease 120, average age 49 years old are observed altogether.Patient has different degrees of chest
The symptoms such as vexed, anterior pectorial region shouting pain, treat apoplexy guideline of clinical investigations TCM syndrome diagnostic criteria by new Chinese medicine and diagnose
For coronary heart disease.Patient is randomly divided into two groups, test group takes the red drop pills of daybreak, and control group takes all ginseng dripping pills of compound.
2 efficacy assessment standards
Apoplexy guideline of clinical investigations tcm syndrome curative effect determinate standard is treated according to new Chinese medicine：
Cure：Tcm clinical practice symptom, sign disappear or basic disappearance, and syndrome integral reduces >=95%.
It is effective：Tcm clinical practice symptom, sign are obviously improved, and syndrome integral reduces >=70%.
Effectively：Tcm clinical practice symptom, sign take a favorable turn, and syndrome integral reduces >=30%.
It is invalid：Tcm clinical practice symptom, sign are not improved or aggravated, and syndrome integral reduces ＜ 30%.
Calculation formula：[（Integrated before treatment after integration-treatment）Integrated before ÷ treatments] × 100%.
3 clinical observation results
The daybreak of table 3 pellet drop pills and compound danshen dripping pills clinical efficacy contrast table
Above-mentioned clinical observation on the therapeutic effect result shows, when the red drop pills of daybreak prepared by the present invention treat coronary heart disease, height evident in efficacy
In the red ball of compound Danshen Root, p ＜ 0.01.
Claims (3)
1. a kind of red drop pills of the Chinese medicine daybreak for treating cardiovascular and cerebrovascular disease, it is characterized in that taking 100~300 parts of rhodiola root, Cassia
100~300 parts of son, 100~300 parts of the red sage root, 100~300 parts of ganoderma lucidum, the refluxing extraction that adds water three times adds water 10 times and measured for the first time,
Extract 3 hours, add water 8 times and measure for the second time, extract 2 hours, add water 8 times and measure for the third time, extract 2 hours, merging filtrate, vacuum is dense
Contracting, spray drying, gets dry extract, crushed 100 mesh sieves, get dry extract powder；Dry cream plus 2 times of amount Macrogol 6000s are taken to mix, control
65~75 DEG C of temperature of charge, 2~10 DEG C of condensation temperature, drop is away from 2.0~4.0 ㎝, and drop speed 20~40 drop per minute instills liquid stone
In wax, taken out after dripping pill shaping, suck surface coolant, be drying to obtain, the red drop pills of daybreak are made.
2. the preparation method of the red drop pills of Chinese medicine daybreak according to claim 1, it is characterized in that 100~300 parts of rhodiola root is taken,
100~300 parts of cassia seed, 100~300 parts of the red sage root, 100~300 parts of ganoderma lucidum, the refluxing extraction that adds water three times adds water 10 for the first time
Measure again, extract 3 hours, add water 8 times and measure for the second time, extract 2 hours, add water 8 times and measure for the third time, extract 2 hours, merging filtrate,
It is concentrated in vacuo, spray drying gets dry extract, crushed 100 mesh sieves, get dry extract powder；Dry cream plus 2 times of amount Macrogol 6000s are taken to mix
It is even, 65~75 DEG C of control material temperature, 2~10 DEG C of condensation temperature, drop is away from 2.0~4.0 ㎝, drop speed 20~40 drop per minute, drop
Enter in atoleine, taken out after dripping pill shaping, suck surface coolant, be drying to obtain, the red drop pills of daybreak are made.
3. the preparation method of the red drop pills of Chinese medicine daybreak according to claim 1, it is characterized in that taking rhodiola root 200g, cassia seed
200g, red sage root 200g, ganoderma lucidum 200g, the refluxing extraction that adds water three times add water 10 times and measured for the first time, extract 3 hours, add water for the second time
8 times of amounts, extract 2 hours, add water 8 times and measure for the third time, extract 2 hours, merging filtrate, are concentrated in vacuo, and spray drying gets dry extract,
100 mesh sieves were crushed, get dry extract powder；Dry cream plus 2 times of amount Macrogol 6000s are taken to mix, control material temperature 70 C, condensation temperature
4 DEG C of degree, drop is away from 2.0~4.0 ㎝, and drop speed 25 drop per minute instills in atoleine, taken out after dripping pill shaping, suck surface cold
But liquid, is drying to obtain, and the red drop pills of daybreak are made.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710471970.3A CN107050108A (en) | 2017-06-20 | 2017-06-20 | Daybreak pellet drop pills and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710471970.3A CN107050108A (en) | 2017-06-20 | 2017-06-20 | Daybreak pellet drop pills and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
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| CN107050108A true CN107050108A (en) | 2017-08-18 |
Family
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| Application Number | Title | Priority Date | Filing Date |
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| CN201710471970.3A Pending CN107050108A (en) | 2017-06-20 | 2017-06-20 | Daybreak pellet drop pills and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113663023A (en) * | 2021-09-26 | 2021-11-19 | 广州颐寿达生物科技有限公司 | A Ganoderma composition for treating hypertension and its preparation method |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1931236A (en) * | 2005-09-14 | 2007-03-21 | 蔡军 | Medicine composition of red sage and rhodiola root |
| CN102614248A (en) * | 2012-04-13 | 2012-08-01 | 孙长海 | Traditional Chinese herbal composite for treating stroke and chest obstruction |
-
2017
- 2017-06-20 CN CN201710471970.3A patent/CN107050108A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1931236A (en) * | 2005-09-14 | 2007-03-21 | 蔡军 | Medicine composition of red sage and rhodiola root |
| CN102614248A (en) * | 2012-04-13 | 2012-08-01 | 孙长海 | Traditional Chinese herbal composite for treating stroke and chest obstruction |
Non-Patent Citations (3)
| Title |
|---|
| 南京中医药大学: "《中药大辞典（第二版）》", 31 March 2006 * |
| 曹鹤剑等: "《《中国当代改革与发展研究文献》——中国当代改革发展理论文献（上）》", 31 July 2004 * |
| 胡英等: "《药物制剂 第2版》", 28 February 2013 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113663023A (en) * | 2021-09-26 | 2021-11-19 | 广州颐寿达生物科技有限公司 | A Ganoderma composition for treating hypertension and its preparation method |
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Application publication date: 20170818 |