CN107049885A - A kind of mouthwash and preparation method thereof - Google Patents
A kind of mouthwash and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
- A61K8/988—Honey; Royal jelly, Propolis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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Abstract
The invention discloses a kind of mouthwash and preparation method thereof, it is related to health treatment technical field, includes the raw material of following part meter：200 ~ 350 parts of 60 ~ 70 parts of bamboo salt, 40 ~ 50 parts of Notogineng Extract, 40 ~ 50 parts of honeysuckle, 30 ~ 40 parts of licorice, 30 ~ 40 parts of the tuber of dwarf lilyturf, 20 ~ 28 parts of vitamin C, 20 ~ 26 parts of vitamin B12,10 ~ 20 parts of Lycopene, 10 ~ 18 parts of Tea Polyphenols, 10 ~ 16 parts of propolis, 5 ~ 15 parts of chrysanthemum indicum, 5 ~ 10 parts of nitre azole drug, 5 ~ 15 parts of auxiliary agent and deionized water.The present invention has anti-inflammatory, analgesic, and effect of sterilization can improve oral inflammation and not destroy Oral normal flora, drug resistance is good, easy to use, good mouthfeel and has no toxic side effect.
Description
Technical field
The present invention relates to health treatment technical field, and in particular to a kind of mouthwash and preparation method thereof.
Background technology
As the improvement of people's living standards, oral hygiene is increasingly valued by people with health, people are not
Brushing teeth twice sooner or later is confined to again, for such crowd, especially for outgoer, has been easy to the mouthwash carried with
Through as one kind life indispensability and fashion.
The content of the invention
It is an object of the invention to provide a kind of mouthwash and preparation method thereof, with anti-inflammatory, analgesic, effect of sterilization, energy
Improve and oral inflammation and do not destroy Oral normal flora, drug resistance is good, easy to use, good mouthfeel and have no toxic side effect.
The invention provides following technical scheme：A kind of mouthwash, includes the raw material of following part meter：60 ~ 70 parts of bamboo salt,
40 ~ 50 parts of Notogineng Extract, 40 ~ 50 parts of honeysuckle, 30 ~ 40 parts of licorice, 30 ~ 40 parts of the tuber of dwarf lilyturf, 20 ~ 28 parts of vitamin C, dimension
Raw 20 ~ 26 parts of element B12,10 ~ 20 parts of Lycopene, 10 ~ 18 parts of Tea Polyphenols, 10 ~ 16 parts of propolis, 5 ~ 15 parts of chrysanthemum indicum, nitre azole medicine
200 ~ 350 parts of 5 ~ 10 parts of thing, 5 ~ 15 parts of auxiliary agent and deionized water；
The auxiliary agent includes the raw material that following part is counted：2 ~ 6 parts of surfactant, 2 ~ 4 parts of sweetener, 2 ~ 4 parts of acid, aromatic
1 ~ 3 part and 1 ~ 2 part of NMF.
Preferably, the raw material of following part meter is included：65 parts of bamboo salt, 45 parts of Notogineng Extract, 45 parts of honeysuckle, licorice 35
Part, 35 parts of the tuber of dwarf lilyturf, 24 parts of vitamin C, 23 parts of vitamin B12,15 parts of Lycopene, 14 parts of Tea Polyphenols, 13 parts of propolis, chrysanthemum indicum
280 parts of 10 parts, 7.5 parts of nitre azole drug, 10 parts of auxiliary agent and deionized water；
The auxiliary agent includes the raw material that following part is counted：4 parts of surfactant, 3 parts of sweetener, 3 parts of acid, 2 parts of aromatic and
1.5 parts of NMF.
Preferably, the preparation method of the bamboo salt is：Day is evaporated brine and is fitted into triennial blue or green bamboo, the natural loess in two ends
Sealing, using pine tree as fuel, under 800 ~ 900 DEG C of hot conditions, calcining refines 2 ~ 3h and obtains the bamboo salt.
Preferably, the preparation method of the Notogineng Extract is：Pseudo-ginseng is rinsed well with clear water, be put into boiling water and boil 5 ~
Taken out after 8min and carry out slicing treatment, the piece thickness of section is 4 ~ 6mm, and the pseudo-ginseng after section is put into the marmite for filling wheat bran
In, heating keeping temperature is natural cooling after 90 ~ 100 DEG C, the 30 ~ 50min that stir-fries, and taking-up crushed 90 ~ 100 mesh sieves, and placed into 2
In 70 ~ 80% ethanol solutions of ~ 4 times of parts by weight, it is Notogineng Extract to obtain extract solution after 5 ~ 7h of immersion refluxing extraction.
Preferably, the nitre azole drug is the one or more in metronidazole, Tinidazole and Ornidazole.
Preferably, the surfactant is sarcosyl, hydroxypropyl methylcellulose sodium and carboxymethyl cellulose
One or more in sodium, the sweetener be saccharin sodium, xylitol, D-sorbite, Aspartame and honey element in
It is one or more of.
Preferably, the acid is the one or more in citric acid, malic acid and tartaric acid, and the aromatic is water
One or more in dissolubility menthol, peppermint essence and fruity essence, the NMF is glycerine or propane diols.
The present invention also provides a kind of preparation method of mouthwash, comprises the following steps：
（1）, honeysuckle, licorice, the tuber of dwarf lilyturf, Notogineng Extract and chrysanthemum indicum are weighed according to proportioning, cleaned and dried with water, crush
And 30 ~ 60 mesh sieves are crossed, and mixing powder is obtained, the deionized water of 10 ~ 15 times of parts by weight of addition into mixing powder, decoction 20~
30min, it is 50 ~ 60 DEG C to decoct temperature control, and filtering retains filtrate, obtains Chinese herbal medicine fluid, standby；
（2）, weigh surfactant, sweetener, acid, aromatic, NMF and deionized water, with 600 ~ 700r/min turn
40 ~ 50min of speed stirring obtains solution A, and surplus stock and step are sequentially added according to proportioning into solution A（1）Obtained medium-height grass
Decoction, continues to stir and heat, the mouthwash is obtained after cooling.
Preferably, the step（2）It is middle to continue to stir and the condition that heats is：It is 60 ~ 70 DEG C to control heating-up temperature, heating
Time is 20 ~ 30min, and mixing speed is 500 ~ 800r/min.
Beneficial effects of the present invention：With anti-inflammatory, analgesic, effect of sterilization can improve oral inflammation and not destroy mouth
Chamber normal flora, drug resistance is good, easy to use, good mouthfeel and has no toxic side effect, specific as follows：
（1）, the present invention in boil after mouthwash not only have anti-inflammation relieve pain effect, to treatment periodontitis effect show
Write, but also can be with fresh breath, holding oral cleaning health；
（2）, the bamboo salt added in the present invention, enteral stool can be removed by power of impregnation and osmotic pressure with detoxication and toxicant eliminating function, bamboo salt,
Into the body fluid of the whole bodies such as saliva, gastric juice, blood, toxin is excreted, bamboo salt can also active balance human body nutrition, it is and right
Acidic constitution can accomplish effective, direct improve；
（3）, the honeysuckle added in the present invention, with clearing heat and detoxicating, effect of wind-heat dissipating, available for preventing anemopyretic cold,
Warm disease heating；The licorice of addition, invigorates the spleen and benefits qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, and relieving spasm to stop pain is weakness of the spleen and the stomach for improving, tired
It is idle weak, palpitation；The chrysanthemum indicum of addition：Also there is good antihypertensive effect while with clearing heat and detoxicating effect, can
For the auxiliary treatment of high blood pressure, to staphylococcus aureus, corynebacterium diphtheriae, streptococcus, Pseudomonas aeruginosa, puncture Shigella, stream
Influenza Virus plays inhibitory action；The tuber of dwarf lilyturf of addition can be used for Yin nourishing and lung moistening, and relieving restlessness that clears away heart-fire, reinforcing stomach reg fluid are controlled dryness of the lung dry cough, told
Blood, spitting of blood, consumptive disease dysphoria with smothery sensation etc.；
（4）, there is hemostasis, anti-caries, anti-inflammatory etc. to act on for the Notogineng Extract that adds in the present invention.The present invention mainly utilizes three
7th, the pharmacological effect such as anti-inflammatory, hemostasis, anti-caries of sodium fluoride, the active component of Notogineng Extract as mouthwash is added and gargled
In saliva so that mouthwash of the invention has outside common tooth-cleaning action, also with prevent periodontitis, gingivitis, oral cavity burst
Ulcer etc. is acted on；
（5）, the vitamin B12 that adds in the present invention, various focusing depths represented can be mitigated, promote canker sore healing, it is safe and stingless
Swash property, will not produce causes microbial resistance, tooth discoloration, oral cavity exsiccation etc. because of long-term use；
（6）, add nitre azole drug in the present invention, have special efficacy to the anaerobic bacteria for causing halitosis, cooperate with medicinal herb componentses, plus
Strong halitosis removal effect, balances Oral normal flora.
Embodiment
With reference to specific embodiment, the present invention is expanded on further.These embodiments be merely to illustrate the present invention and without
In limitation the scope of the present invention.
Embodiment 1
A kind of mouthwash, includes the raw material of following part meter：60 parts of bamboo salt, 40 parts of Notogineng Extract, 40 parts of honeysuckle, licorice 30
Part, 30 parts of the tuber of dwarf lilyturf, 20 parts of vitamin C, 20 parts of vitamin B12,10 parts of Lycopene, 10 parts of Tea Polyphenols, 10 parts of propolis, chrysanthemum indicum
200 parts of 5 parts, 5 parts of nitre azole drug, 5 parts of auxiliary agent and deionized water；
The auxiliary agent includes the raw material that following part is counted：2 parts of surfactant, 2 parts of sweetener, 2 parts of acid, 1 part of aromatic and
1 part of NMF.
Wherein, the preparation method of the bamboo salt is：Day is evaporated brine and is fitted into triennial blue or green bamboo, two ends are sealed with natural loess
Mouthful, using pine tree as fuel, under 800 DEG C of hot conditions, calcining refines 2h and obtains the bamboo salt.
Wherein, the preparation method of the Notogineng Extract is：Pseudo-ginseng is rinsed well with clear water, is put into boiling water and boils 5min
After take out and carry out slicing treatment, the piece thickness of section is 4mm, and the pseudo-ginseng after section is put into the marmite for filling wheat bran, plus
Hot keeping temperature is natural cooling after 90 DEG C, the 30min that stir-fries, and taking-up crushed 90 mesh sieves, and placed into 70% second of 2 times of parts by weight
In alcoholic solution, it is Notogineng Extract to obtain extract solution after immersion refluxing extraction 5h.
Wherein, the nitre azole drug is metronidazole, and the surfactant is sarcosyl, the sweet taste
Agent is saccharin sodium.
Wherein, the acid is citric acid, and the aromatic is water-soluble menthol, and the NMF is glycerine.
A kind of preparation method of mouthwash is also provided in the present embodiment, comprised the following steps：
（1）, honeysuckle, licorice, the tuber of dwarf lilyturf, Notogineng Extract and chrysanthemum indicum are weighed according to proportioning, cleaned and dried with water, crush
And 30 mesh sieves are crossed, mixing powder is obtained, the deionized water of 10 times of parts by weight is added into mixing powder, 20min is decocted, temperature is decocted
Degree control is 50 DEG C, and filtering retains filtrate, obtains Chinese herbal medicine fluid, standby；
（2）, weigh surfactant, sweetener, acid, aromatic, NMF and deionized water, stirred with 600r/min rotating speeds
Mix 40min and obtain solution A, surplus stock and step are sequentially added according to proportioning into solution A（1）Obtained Chinese herbal medicine fluid, after
It is continuous to stir and heat, the mouthwash is obtained after cooling.
Preferably, the step（2）It is middle to continue to stir and the condition that heats is：It is 60 DEG C to control heating-up temperature, during heating
Between be 20min, mixing speed is 500r/min.
Embodiment 2
A kind of mouthwash, includes the raw material of following part meter：70 parts of bamboo salt, 50 parts of Notogineng Extract, 50 parts of honeysuckle, licorice 40
Part, 40 parts of the tuber of dwarf lilyturf, 28 parts of vitamin C, 26 parts of vitamin B12,20 parts of Lycopene, 18 parts of Tea Polyphenols, 16 parts of propolis, chrysanthemum indicum
350 parts of 15 parts, 10 parts of nitre azole drug, 15 parts of auxiliary agent and deionized water；
The auxiliary agent includes the raw material that following part is counted：6 parts of surfactant, 4 parts of sweetener, 4 parts of acid, 3 parts of aromatic and
2 parts of NMF.
Wherein, the preparation method of the bamboo salt is：Day is evaporated brine and is fitted into triennial blue or green bamboo, two ends are sealed with natural loess
Mouthful, using pine tree as fuel, under 900 DEG C of hot conditions, calcining refines 3h and obtains the bamboo salt.
Wherein, the preparation method of the Notogineng Extract is：Pseudo-ginseng is rinsed well with clear water, is put into boiling water and boils 8min
After take out and carry out slicing treatment, the piece thickness of section is 6mm, and the pseudo-ginseng after section is put into the marmite for filling wheat bran, plus
Hot keeping temperature is natural cooling after 100 DEG C, the 50min that stir-fries, and taking-up crushed 100 mesh sieves, and placed into the 80% of 4 times of parts by weight
In ethanol solution, it is Notogineng Extract to obtain extract solution after immersion refluxing extraction 7h.
Wherein, the nitre azole drug is Ornidazole, and the surfactant is sodium carboxymethylcellulose, the sweetener
For D-sorbite.
Wherein, the acid is tartaric acid, and the aromatic is fruity essence, and the NMF is propane diols.
The present embodiment also provides a kind of preparation method of mouthwash, comprises the following steps：
（1）, honeysuckle, licorice, the tuber of dwarf lilyturf, Notogineng Extract and chrysanthemum indicum are weighed according to proportioning, cleaned and dried with water, crush
And 60 mesh sieves are crossed, mixing powder is obtained, the deionized water of 15 times of parts by weight is added into mixing powder, 30min is decocted, temperature is decocted
Degree control is 60 DEG C, and filtering retains filtrate, obtains Chinese herbal medicine fluid, standby；
（2）, weigh surfactant, sweetener, acid, aromatic, NMF and deionized water, stirred with 700r/min rotating speeds
Mix 50min and obtain solution A, surplus stock and step are sequentially added according to proportioning into solution A（1）Obtained Chinese herbal medicine fluid, after
It is continuous to stir and heat, the mouthwash is obtained after cooling.
Wherein, the step（2）It is middle to continue to stir and the condition that heats is：It is 70 DEG C, heat time to control heating-up temperature
For 30min, mixing speed is 800r/min.
Embodiment 3
A kind of mouthwash, includes the raw material of following part meter：65 parts of bamboo salt, 45 parts of Notogineng Extract, 45 parts of honeysuckle, licorice 35
Part, 35 parts of the tuber of dwarf lilyturf, 24 parts of vitamin C, 23 parts of vitamin B12,15 parts of Lycopene, 14 parts of Tea Polyphenols, 13 parts of propolis, chrysanthemum indicum
280 parts of 10 parts, 7.5 parts of nitre azole drug, 10 parts of auxiliary agent and deionized water；
The auxiliary agent includes the raw material that following part is counted：4 parts of surfactant, 3 parts of sweetener, 3 parts of acid, 2 parts of aromatic and
1.5 parts of NMF.
Wherein, the preparation method of the bamboo salt is：Day is evaporated brine and is fitted into triennial blue or green bamboo, two ends are sealed with natural loess
Mouthful, using pine tree as fuel, under 850 DEG C of hot conditions, calcining refines 2.5h and obtains the bamboo salt.
Wherein, the preparation method of the Notogineng Extract is：Pseudo-ginseng is rinsed well with clear water, is put into boiling water and boils 6min
After take out and carry out slicing treatment, the piece thickness of section is 5mm, and the pseudo-ginseng after section is put into the marmite for filling wheat bran, plus
Hot keeping temperature is natural cooling after 95 DEG C, the 40min that stir-fries, and taking-up crushed 95 mesh sieves, and placed into 75% second of 3 times of parts by weight
In alcoholic solution, it is Notogineng Extract to obtain extract solution after immersion refluxing extraction 6h.
Wherein, the nitre azole drug is Tinidazole, and the surfactant is hydroxypropyl methylcellulose sodium, the sweetener
For D-sorbite.
Preferably, the acid is malic acid, and the aromatic is fruity essence, and the NMF is glycerine.
The present embodiment also provides a kind of preparation method of mouthwash, comprises the following steps：
（1）, honeysuckle, licorice, the tuber of dwarf lilyturf, Notogineng Extract and chrysanthemum indicum are weighed according to proportioning, cleaned and dried with water, crush
And 45 mesh sieves are crossed, mixing powder is obtained, the deionized water of 12.5 times of parts by weight is added into mixing powder, 25min is decocted, decocted
Temperature control is 55 DEG C, and filtering retains filtrate, obtains Chinese herbal medicine fluid, standby；
（2）, weigh surfactant, sweetener, acid, aromatic, NMF and deionized water, stirred with 650r/min rotating speeds
Mix 45min and obtain solution A, surplus stock and step are sequentially added according to proportioning into solution A（1）Obtained Chinese herbal medicine fluid, after
It is continuous to stir and heat, the mouthwash is obtained after cooling.
Wherein, the step（2）It is middle to continue to stir and the condition that heats is：It is 65 DEG C, heat time to control heating-up temperature
For 25min, mixing speed is 650r/min.
The present invention is described in detail with reference to the foregoing embodiments, for those skilled in the art, its according to
The technical scheme described in foregoing embodiments can so be modified, or which part technical characteristic is equally replaced
Change.Within the spirit and principles of the invention, any modification, equivalent substitution and improvements made etc., should be included in the present invention
Protection domain within.
Claims (9)
1. a kind of mouthwash, it is characterised in that the raw material counted including following part：60 ~ 70 parts of bamboo salt, 40 ~ 50 parts of Notogineng Extract,
40 ~ 50 parts of honeysuckle, 30 ~ 40 parts of licorice, 30 ~ 40 parts of the tuber of dwarf lilyturf, 20 ~ 28 parts of vitamin C, 20 ~ 26 parts of vitamin B12, eggplant
10 ~ 20 parts of red pigment, 10 ~ 18 parts of Tea Polyphenols, 10 ~ 16 parts of propolis, 5 ~ 15 parts of chrysanthemum indicum, 5 ~ 10 parts of nitre azole drug, auxiliary agent 5 ~ 15
200 ~ 350 parts of part and deionized water；
The auxiliary agent includes the raw material that following part is counted：2 ~ 6 parts of surfactant, 2 ~ 4 parts of sweetener, 2 ~ 4 parts of acid, aromatic
1 ~ 3 part and 1 ~ 2 part of NMF.
2. mouthwash according to claim 1, it is characterised in that the raw material counted including following part：65 parts of bamboo salt, pseudo-ginseng carry
Take 45 parts of thing, 45 parts of honeysuckle, 35 parts of licorice, 35 parts of the tuber of dwarf lilyturf, 24 parts of vitamin C, 23 parts of vitamin B12, Lycopene 15
Part, 14 parts of Tea Polyphenols, 13 parts of propolis, 10 parts of chrysanthemum indicum, 7.5 parts of nitre azole drug, 10 parts of auxiliary agent and 280 parts of deionized water；
The auxiliary agent includes the raw material that following part is counted：4 parts of surfactant, 3 parts of sweetener, 3 parts of acid, 2 parts of aromatic and
1.5 parts of NMF.
3. mouthwash according to claim 1, it is characterised in that the preparation method of the bamboo salt is：By loading of evaporating brine day
In triennial blue or green bamboo, two ends are sealed with natural loess, using pine tree as fuel, under 800 ~ 900 DEG C of hot conditions, calcining
Refine 2 ~ 3h and obtain the bamboo salt.
4. mouthwash according to claim 1, it is characterised in that the preparation method of the Notogineng Extract is：By pseudo-ginseng
Rinsed well with clear water, be put into boiling water to boil and slicing treatment is taken out and carried out after 5 ~ 8min, the piece thickness of section is 4 ~ 6mm, will be cut
Pseudo-ginseng after piece is put into the marmite for filling wheat bran, heats keeping temperature for 90 ~ 100 DEG C, naturally cold after the 30 ~ 50min that stir-fries
But, take out and crushed 90 ~ 100 mesh sieves, in 70 ~ 80% ethanol solutions for placing into 2 ~ 4 times of parts by weight, soak 5 ~ 7h of refluxing extraction
It is Notogineng Extract to obtain extract solution afterwards.
5. mouthwash according to claim 1, it is characterised in that the nitre azole drug is metronidazole, Tinidazole and Austria
One or more in nitre azoles.
6. mouthwash according to claim 1, it is characterised in that the surfactant be sarcosyl,
One or more in hydroxypropyl methylcellulose sodium and sodium carboxymethylcellulose, the sweetener is saccharin sodium, xylitol, sorbose
One or more in alcohol, Aspartame and honey element.
7. mouthwash according to claim 1, it is characterised in that the acid is citric acid, malic acid and tartaric acid
In one or more, the aromatic is the one or more in water-soluble menthol, peppermint essence and fruity essence, described
NMF is glycerine or propane diols.
8. the preparation method of a kind of mouthwash according to any one of claim 1 ~ 7, it is characterised in that including following step
Suddenly：
（1）, honeysuckle, licorice, the tuber of dwarf lilyturf, Notogineng Extract and chrysanthemum indicum are weighed according to proportioning, cleaned and dried with water, crush
And 30 ~ 60 mesh sieves are crossed, and mixing powder is obtained, the deionized water of 10 ~ 15 times of parts by weight of addition into mixing powder, decoction 20~
30min, it is 50 ~ 60 DEG C to decoct temperature control, and filtering retains filtrate, obtains Chinese herbal medicine fluid, standby；
（2）, weigh surfactant, sweetener, acid, aromatic, NMF and deionized water, with 600 ~ 700r/min turn
40 ~ 50min of speed stirring obtains solution A, and surplus stock and step are sequentially added according to proportioning into solution A（1）Obtained medium-height grass
Decoction, continues to stir and heat, the mouthwash is obtained after cooling.
9. the preparation method of mouthwash according to claim 8, it is characterised in that the step（2）It is middle to continue to stir simultaneously
The condition of heating is：It is 60 ~ 70 DEG C to control heating-up temperature, and the heat time is 20 ~ 30min, and mixing speed is 500 ~ 800r/min.
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| CN201710476413.0A CN107049885A (en) | 2017-06-21 | 2017-06-21 | A kind of mouthwash and preparation method thereof |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107929217A (en) * | 2018-01-22 | 2018-04-20 | 郭心畅 | Propolis herbal mouthwash |
| CN109125176A (en) * | 2018-09-28 | 2019-01-04 | 江苏瑾辉生物科技有限公司 | One kind gargle containing tea polyphenols and preparation method thereof |
| CN109431901A (en) * | 2018-12-13 | 2019-03-08 | 中原工学院 | A kind of effectively antibacterial salting liquid of gargling |
| CN109431938A (en) * | 2018-12-13 | 2019-03-08 | 中原工学院 | A kind of salting liquid of gargling that laryngopharyngitis is effectively relieved |
| CN113830398A (en) * | 2021-10-29 | 2021-12-24 | 南京鼓楼医院 | Portable gargle set |
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| CN102949317A (en) * | 2012-11-30 | 2013-03-06 | 银川高新区广煜科技有限公司 | Special mouthwash for Moslems |
| CN103006525A (en) * | 2012-12-20 | 2013-04-03 | 青岛力宇仓储机械设备有限公司 | Smoke stain removal mouthwash |
| CN104107161A (en) * | 2014-07-03 | 2014-10-22 | 河南科技大学第一附属医院 | Mouthwash used for nursing oral cavity and preparation method thereof |
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| CN1506038A (en) * | 2002-12-09 | 2004-06-23 | �����š�������ŵ��������� | Oral hygienic product with melatonin alkali as active substance to supply human and animal use |
| CN101756850A (en) * | 2008-11-18 | 2010-06-30 | 陈恩平 | Escin mouthwash for preventing and treating periodontitis |
| CN102949317A (en) * | 2012-11-30 | 2013-03-06 | 银川高新区广煜科技有限公司 | Special mouthwash for Moslems |
| CN103006525A (en) * | 2012-12-20 | 2013-04-03 | 青岛力宇仓储机械设备有限公司 | Smoke stain removal mouthwash |
| CN104107161A (en) * | 2014-07-03 | 2014-10-22 | 河南科技大学第一附属医院 | Mouthwash used for nursing oral cavity and preparation method thereof |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107929217A (en) * | 2018-01-22 | 2018-04-20 | 郭心畅 | Propolis herbal mouthwash |
| CN109125176A (en) * | 2018-09-28 | 2019-01-04 | 江苏瑾辉生物科技有限公司 | One kind gargle containing tea polyphenols and preparation method thereof |
| CN109431901A (en) * | 2018-12-13 | 2019-03-08 | 中原工学院 | A kind of effectively antibacterial salting liquid of gargling |
| CN109431938A (en) * | 2018-12-13 | 2019-03-08 | 中原工学院 | A kind of salting liquid of gargling that laryngopharyngitis is effectively relieved |
| CN113830398A (en) * | 2021-10-29 | 2021-12-24 | 南京鼓楼医院 | Portable gargle set |
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