CN107049309A - Auditory brainstem response detection method and device - Google Patents
Auditory brainstem response detection method and device Download PDFInfo
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- CN107049309A CN107049309A CN201710342601.4A CN201710342601A CN107049309A CN 107049309 A CN107049309 A CN 107049309A CN 201710342601 A CN201710342601 A CN 201710342601A CN 107049309 A CN107049309 A CN 107049309A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/369—Electroencephalography [EEG]
- A61B5/377—Electroencephalography [EEG] using evoked responses
- A61B5/38—Acoustic or auditory stimuli
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
Abstract
The embodiment of the invention discloses a kind of auditory brainstem response detection method and device.Methods described includes：Synthesis can compensate for the time domain frequency sweep voice signal of basilar membrane traveling wave delay；Auditory system is stimulated using the time domain frequency sweep voice signal, auditory brainstem response ABR waveforms are obtained.The embodiment of the present invention can compensate for the time domain frequency sweep voice signal that basilar membrane traveling wave postpones by synthesis, and auditory system is stimulated using the time domain frequency sweep voice signal of synthesis, can obtain accurate ABR waveforms.
Description
Technical field
The present embodiments relate to neural field of engineering technology, more particularly to a kind of auditory brainstem response detection method
And device.
Background technology
For given sonic stimulation, auditory system can produce a series of nerve nucleus in potentiometric responses, sense of hearing conduction path
Roll into a ball and its nerve fibre can be stimulated excited and produces small potential change.Changed by the waveform for recording these current potentials, and
It is extracted from various strong noise backgrounds using various digital signal processing algorithms, as auditory brainstem response,
It is the important indicator for evaluating sense of hearing conducting system integrality and monitoring nervous function.
The auditory brainstem response that clinic is generally detected is by the 5-7 induced after sonic stimulation continuous brain waves
Peak, each peak separation about 1ms, total duration is 8-10ms.The crest of wherein more stable appearance is I ripples, II ripples, III
Ripple, IV ripples and V ripples.It is generally acknowledged that I ripples come from auditory nerve, II ripples come from snail core, and III ripples come from upper superior olivary complex, and IV ripples come
From lemniscus lateralis, V ripples come from inferior colliculus., typically can be by observing auditory brainstem response (Auditory in clinical practice
Brainstem Response, ABR) missing of waveform or the extension of wave crest delitescence understand patient's threshold of audibility situation, judge
Whether its auditory system is damaged or whether nervous function is complete, and further determines lesion according to the crest for exception occur
Position.ABR waveforms detections are also particularly significant for UNHS.
At present, short sound and short tone burst stimulation are often used in ABR waveforms detections.Short sound is a kind of wide spectrum stimulation sound, typically
Transient or the vibration signals such as the stimulation square wave for certain pulsewidth, can be set certain sound intensity and stimulate repetitive rate；Although short sound
Stimulate frequency spectrum wider, a variety of frequency of stimulation can be included, but short sound typically reflects hearing water of the subject in high band (2-4kHz)
It is flat, and specific frequency is low.Tone burst is then smaller for a kind of time-histories, the tonal signal with preferable specific frequency, reaction threshold
There is good correlation with subjective hearing thresholds.
But, as ABR waveforms detections stimulate sound source short sound and tone burst, be when sound is sent its include it is each
Frequency content voice signal is simultaneously emitted by, and fails to consider the traveling wave delay of sound conduction, thus causes last superposed average
Obtained ABR signals there may be each frequency content signal cancel each other influence the problem of, cause ABR signal qualitys not good, from
And cause the ABR waveform range of reactions induced smaller, it is impossible to obtain most accurate ABR waveforms.
The content of the invention
The embodiment of the present invention provides a kind of auditory brainstem response detection method and device, can obtain accurately
ABR waveforms.
In a first aspect, the embodiments of the invention provide a kind of auditory brainstem response detection method, this method includes：
Synthesis can compensate for the time domain frequency sweep voice signal of basilar membrane traveling wave delay；
Auditory system is stimulated using the time domain frequency sweep voice signal, auditory brainstem response ABR waveforms are obtained.
Second aspect, the embodiment of the present invention additionally provides a kind of auditory brainstem response detection means, and the device includes：
Voice signal synthesis module, the time domain frequency sweep sound letter of basilar membrane traveling wave delay is can compensate for for synthesizing
Number；
ABR waveform detection modules, for being stimulated using the time domain frequency sweep voice signal auditory system, are listened
Property brain stem response ABR waveforms.
The embodiment of the present invention can compensate for the time domain frequency sweep voice signal that basilar membrane traveling wave postpones by synthesis, and adopt
Auditory system is stimulated with the time domain frequency sweep voice signal of synthesis, accurate ABR waveforms can be obtained.
Brief description of the drawings
Figure 1A is a kind of flow chart for auditory brainstem response detection method that the embodiment of the present invention one is provided；
Figure 1B is the basilar membrane in a kind of auditory brainstem response detection method that the embodiment of the present invention one is provided
Expansion model schematic diagram；
Fig. 1 C are the basilar membranes in a kind of auditory brainstem response detection method that the embodiment of the present invention one is provided
Traveling wave postpones and frequency relation curve schematic diagram；
Fig. 2A is a kind of flow chart for auditory brainstem response detection method that the embodiment of the present invention two is provided；
Fig. 2 B be the embodiment of the present invention two provide a kind of auditory brainstem response detection method in set sound letter
Number phase spectrum schematic diagram；
Fig. 2 C be the embodiment of the present invention two provide a kind of auditory brainstem response detection method in set sound letter
Number amplitude spectrum schematic diagram；
Fig. 2 D are that the time domain that synthesizes is swept in a kind of auditory brainstem response detection method that the embodiment of the present invention two is provided
Frequency voice signal schematic diagram；
Fig. 2 E are that the short acoustical signal in a kind of auditory brainstem response detection method that the embodiment of the present invention two is provided is shown
It is intended to；
Fig. 2 F are the short acoustical signals pair in a kind of auditory brainstem response detection method that the embodiment of the present invention two is provided
The frequency content schematic diagram answered；
Fig. 2 G be the embodiment of the present invention two provide a kind of auditory brainstem response detection method in synthesis time domain
Scan the corresponding frequency content schematic diagram of voice signal；
Fig. 2 H are the short sound letters of use in a kind of auditory brainstem response detection method that the embodiment of the present invention two is provided
Number stimulate and obtain ABR waveform diagrams；
Fig. 2 I are the use synthesis in a kind of auditory brainstem response detection method that the embodiment of the present invention two is provided
Time domain frequency sweep voice signal stimulate obtaining ABR waveform diagrams；
Fig. 3 is a kind of structure chart for auditory brainstem response detection means that the embodiment of the present invention three is provided.
Embodiment
In order that the object, technical solutions and advantages of the present invention are clearer, below in conjunction with the accompanying drawings to specific reality of the invention
Example is applied to be described in further detail.It is understood that specific embodiment described herein is used only for explaining the present invention,
Rather than limitation of the invention.
It also should be noted that, for the ease of description, illustrate only in accompanying drawing part related to the present invention rather than
Full content.It should be mentioned that some exemplary embodiments are described before exemplary embodiment is discussed in greater detail
Into the processing or method described as flow chart.Although operations (or step) are described as the processing of order by flow chart,
It is that many of which operation can be by concurrently, concomitantly or while implement.In addition, the order of operations can be by again
Arrange.The processing can be terminated when its operations are completed, it is also possible to the additional step being not included in accompanying drawing.
The processing can correspond to method, function, code, subroutine, subprogram etc..
Embodiment one
Figure 1A is a kind of flow chart for auditory brainstem response detection method that the embodiment of the present invention one is provided, this implementation
Example is applicable to the situation of auditory brainstem response detection, and this method can be lured by auditory brainstem provided in an embodiment of the present invention
Generating level detecting apparatus is performed, and the device can realize that the device can be integrated in terminal and set by the way of software and/or hardware
In standby or in the application end of terminal device.Wherein, terminal device can be but be not limited to mobile terminal (tablet personal computer or intelligence
Mobile phone), fixed terminal (desktop computer or notebook).
Wherein, application end can be the plug-in unit for some client being embedded in terminal device, or be set for the terminal
The plug-in unit of standby operating system, with the auditory brainstem response detection client or terminal device being embedded in terminal device
Operating system in auditory brainstem response detection application program use cooperatively；Application end can also be the terminal device
In an independent client that auditory brainstem response detection is provided, the present embodiment is not limited to this.
As described in Figure 1A, the method for the present embodiment is specifically included：
S101, synthesis can compensate for the time domain frequency sweep voice signal of basilar membrane traveling wave delay.
Necessarily postpone because sound conduction has in the traveling wave of basilar membrane, short sound or tone burst fail to consider cochlea
Basilar memebrane postpones to the traveling wave of sound conduction, all it cannot be guaranteed that sound source stimulates the synchronism of cochlea inner hair cell neuronal excitation,
Therefore the synthesis of this step can compensate for the time domain frequency sweep voice signal of basilar membrane traveling wave delay, to compensate basilar membrane row
Ripple postpones, and improves the signal quality of auditory brainstem response and improves the reliability of measurement result.
Specifically, original letter can be regard existing tonal signal (such as tone burst), complex tone signal (for example, short sound) as
Number, on the basis of the primary signal, synthesis can compensate for the time domain frequency sweep voice signal of basilar membrane traveling wave delay.In tool
When body is realized, time domain frequency sweep voice signal can be synthesized according to the characteristic of basilar membrane.
As shown in Figure 1B, basilar membrane has the property that：Due to the basilar membrane of flattening be one by bottom to
Top is gradually by the narrow film broadened, and bottom narrow rigid is sensitive to high-frequency signal；Top is roomy soft, quick to low frequency signal
Sense.Therefore early stage scholar proposes the theory on basilar membrane phonosensitive characteristic, is carried earliest including Feng's Helmholtz
Resonance theory, the frequency theory that W rutherford proposes and the western travelling wave theory in Bake generally acknowledged at present for most scholars gone out.Three
The frequency characteristic that theory all supports basilar membrane is planted, i.e. each position of basilar membrane correspond to one specifically
Frequency, the sound wave of different frequency is different at the position that basilar membrane produces peak swing.
For tonal signal, frequency of sound wave is lower, produces the position of peak swing at the top of basilar membrane, and production
Time delay needed for raw peak swing is longer；Frequency of sound wave is higher, produces the position of peak swing closer to basilar membrane
Time delay needed for bottom, and generation peak swing is shorter, as shown in Figure 1 C.The size of frequency determines basilar membrane traveling wave
Peak swing produced by position.Therefore, tonal signal can be handled based on features described above, obtains can compensate for cochlea
The time domain frequency sweep voice signal of basilar memebrane traveling wave delay.
For complex tone signal, basilar membrane can convert the different frequency of complex tone signal the difference in basilar membrane
Position, while different intensities of sound is converted into different basilar membrane Oscillation Amplitudes, so as to isolate complex tone letter
Different frequency composition and corresponding amplitude in number, complete basilar membrane to sound frequency and the coding of intensity.Basilar membrane
Position and characteristic frequency relation be in inverse ratio curve relation.Because basilar membrane has a frequency selectivity, therefore 35mm length
Basilar membrane can equivalent to the bandpass filter of one group of certain bandwidth parallel connection.It is sensitive to low-frequency range at the top of basilar membrane,
Broader bandwidth；Basilar membrane bottom is sensitive to high band, narrower bandwidth, filter bandwidht with basilar membrane change in location
And change.Therefore, complex tone signal can be handled based on features described above, obtains can compensate for the delay of basilar membrane traveling wave
Time domain frequency sweep voice signal.
S102, using the time domain frequency sweep voice signal auditory system is stimulated, obtain auditory brainstem response ABR ripples
Shape.
Specifically, being stimulated using the time domain frequency sweep voice signal auditory system, periphery hearing organ can be caused
And brain stem, about the potential change of structure (for example, nerve nucleus and its nerve fibre in sense of hearing conduction path), these current potentials become
Change can be recorded on scalp electrode, i.e. ABR signals, obtain ABR waveforms by the measurement to ABR signals, ABR waveforms can
To reflect the functional status of brain stem and its integrality of structure.
The present embodiment can compensate for the time domain frequency sweep voice signal that basilar membrane traveling wave postpones by synthesis, to compensate ear
Snail basilar memebrane traveling wave postpones, and can improve the signal quality of auditory brainstem response, obtain accurate ABR waveforms, from
And improve the reliability of measurement result.
Embodiment two
Fig. 2A is a kind of flow chart for auditory brainstem response detection method that the embodiment of the present invention two is provided.This implementation
Example is optimized based on above-described embodiment, in the present embodiment, and the synthesis can compensate for into basilar membrane traveling wave prolongs
Slow time domain frequency sweep voice signal is optimized for：According to sound conduction in the traveling wave delay model of basilar membrane, adjusted in frequency domain
The delay of each frequency of voice signal, obtains can compensate for the frequency domain frequency sweep voice signal of basilar membrane traveling wave delay；To described
Frequency domain frequency sweep voice signal carries out frequency domain inverse Fourier transform and obtains the time domain frequency sweep voice signal.
Accordingly, the method for the present embodiment is specifically included：
S201, according to sound conduction basilar membrane traveling wave delay model, frequency domain adjust each frequency of voice signal
Delay, obtain can compensate for the frequency domain frequency sweep voice signal of basilar membrane traveling wave delay.
A kind of achievable embodiment of this step is, according to sound conduction basilar membrane traveling wave delay model,
In frequency domain, the corresponding one or more of frequency domain value of voice signal is set：Phase, frequency and amplitude.
For example, being intensity of sound for the different phase of each set of frequency of voice signal, identical amplitude, to adjust sound
The delay of signal different frequency, i.e. high-frequency sound signal delay are big, and low frequency sound signals delay is small, makes each frequency of voice signal same
When reach at each specific frequency of basilar membrane, while stimulating cochlea inner hair cell neuronal excitation to produce maximizes current potential, lure
Send out the ABR waveforms optimized.
Another achievable embodiment of this step is that the traveling wave according to sound conduction in basilar membrane postpones mould
Type, fits the inverse ratio curve relation of basilar membrane group delay and characteristic frequency；According to the inverse ratio curve relation setting sound
The phase spectrum and/or amplitude spectrum of message number.
For example, according to sound conduction basilar membrane traveling wave delay model, with formula fitting go out the time delay with
The curved line relation of frequency, as shown in Figure 1 C, i.e. low frequency time delay are long, high frequency time delay short inverse ratio curve, and frequency domain is accumulated
Phase and frequency relation can be obtained by dividing, that is, obtain phase spectrum, as shown in Figure 2 B, wherein, phase phase=-24.35*x (f
)1.409；And/or, by the intensity of sound to the same amplitude of each set of frequency of voice signal, that is, amplitude spectrum is obtained, such as Fig. 2 C institutes
Show, wherein amplitude value is 100db.
S202, to the frequency domain frequency sweep voice signal carry out inverse transformation obtain the time domain frequency sweep voice signal.
Wherein, it is adoptable to be inversely transformed into inverse Fourier transform.
For example, being back-calculated to obtain time domain frequency sweep voice signal by inverse Fourier transform, as shown in Figure 2 D, you can obtain with good
Good frequency characteristic, broad spectrum, the stronger sound intensity and the frequency sweep ABR stimulation sound of compensation basilar membrane traveling wave delay can be corresponded to.
Comprise the following steps that：Evoked otoacoustic emissions SFOAE group delays are in inverse ratio curve relation with characteristic frequency, and cochlea
Basilar memebrane group delay is with characteristic frequency relation shown in 1/2 times of equation below of Evoked otoacoustic emissions and characteristic frequency relation：
Wherein, traveling wave of x (f) the representative voices signal at each frequency, τBMEach frequency of [x (f), f] representative voice signal exists
The group delay of basilar membrane, τSFOAE(f) group delay of the Evoked otoacoustic emissions at each frequency, is represented.
Therefore from formula, basilar membrane group delay is also in inverse ratio curve relation, i.e. low frequency with characteristic frequency relation
Signal group delay is big, and high-frequency signal group delay is small, therefore by obtaining the phase spectrum of each frequency acoustic signal to frequency integrator, such as
Shown in Fig. 2 B.Realization makes low frequency signal first send in frequency domain adjustment phase place, is sent after high-frequency signal, then by setting each frequency sound
The sound intensity amplitude of message number, obtains the voice signal amplitude spectrum of the identical sound intensity.By gained when frequency sweep voice signal amplitude spectrum and
Phase spectrum, sets sample frequency and completion negative frequency part, the time domain of frequency sweep voice signal is back-calculated to obtain by inverse Fourier transform
Signal.
The time domain frequency sweep voice signal synthesized by above step can compensate the row of basilar membrane at each specific frequency
Ripple postpones, and makes the voice signal of each frequency while reaching at each specific frequency of basilar membrane, while stimulating cochlea inner hair cell
Neuronal excitation produces maximum potential, i.e., due to the synchronism that ensure that the inner hair cell neuronal excitation at each frequency, thus
The maximum ABR waveforms of range of reaction can be induced.
S203, using the time domain frequency sweep voice signal auditory system is stimulated, obtain auditory brainstem response ABR ripples
Shape.
In the detection of actual clinical auditory brainstem response, earphone audition is generally worn, therefore human ear is wearing ear
Machine be followed by the quieting down amplitude spectrum and phase spectrum of sound is slightly changed, and the present embodiment can be realized by above step and frequency sweep is pierced in frequency domain
The phase and sound intensity amplitude for swashing each frequency of sound are adjusted in real time, are allowed to, close to distortionless optimal situation, be finally reached reception
Pleasant frequency sweep stimulates acoustic energy to maximize, synchronization stimulates the full basilar memebrane vibration of cochlea, while excited produce maximum potential, obtains
Optimize the effect of ABR detection waveforms.
The short acoustical signal of prior art is respectively adopted and the time domain frequency sweep voice signal of the present embodiment synthesis is tested.Its
In, as shown in Figure 2 E, its corresponding each frequency content is as shown in Figure 2 F for short acoustical signal.Wherein, the time domain of the present embodiment synthesis is swept
As shown in Figure 2 D, its corresponding each frequency content is as shown in Figure 2 G for frequency voice signal.Using the time domain frequency sweep voice signal pair
Auditory system is stimulated, obtained ABR waveforms as illustrated in figure 2h, using the time domain frequency sweep voice signal of synthesis to auditory system
Stimulated, obtain ABR waveforms as shown in figure 2i.It can be seen that, the time domain frequency sweep voice signal of the present embodiment synthesis has well
Specific frequency so that can effective detection auditory system to the auditory acuity of a certain specific frequency, and can compensating sound conduction in ear
The traveling wave delay of snail basilar memebrane so that each frequency content of stimulation sound can be reached at each specific frequency of basilar membrane simultaneously, simultaneously
Stimulate inner hair cell neuronal excitation to reach maximum potential, produce range of reaction and maximize and the most accurate ABR waveforms of waveform.
Embodiment three
Fig. 3 is a kind of structure chart for auditory brainstem response detection means that the embodiment of the present invention three is provided, this implementation
Example is applicable to the situation of auditory brainstem response detection, and the device can be realized by the way of software and/or hardware, the dress
Putting can be integrated in terminal device or in the application end of terminal device.Wherein, terminal device can be but be not limited to mobile whole
Hold (tablet personal computer or smart mobile phone), fixed terminal (desktop computer or notebook).
Wherein, application end can be the plug-in unit for some client being embedded in terminal device, or be set for the terminal
The plug-in unit of standby operating system, with the auditory brainstem response detection client or terminal device being embedded in terminal device
Operating system in auditory brainstem response detection application program use cooperatively；Application end can also be the terminal device
In an independent client that auditory brainstem response detection is provided, the present embodiment is not limited to this.
As shown in figure 3, described device includes：Voice signal synthesis module 31 and ABR waveform detection modules 32, wherein：
Voice signal synthesis module 31 is used to synthesize the time domain frequency sweep sound letter that can compensate for the delay of basilar membrane traveling wave
Number；
ABR waveform detection modules 32 are used to stimulate auditory system using the time domain frequency sweep voice signal, obtain
Auditory brainstem response ABR waveforms.
The auditory brainstem response detection means of the present embodiment is used for the Auditory Brainstem Response for performing the various embodiments described above
Potentiometric detection method, its technical principle is similar with the technique effect produced, repeats no more here.
On the basis of the various embodiments described above, the voice signal synthesis module 31 includes：Frequency-region signal synthesis unit 311
With frequency-region signal synthesis unit 312.
Frequency-region signal synthesis unit 311 is used for the traveling wave delay model in basilar membrane according to sound conduction, in frequency domain
The delay of each frequency of voice signal is adjusted, obtains can compensate for the frequency domain frequency sweep voice signal of basilar membrane traveling wave delay；
Inverse transformation block 312 is used to obtain the time domain frequency sweep sound to frequency domain frequency sweep voice signal progress inverse transformation
Signal.
On the basis of the various embodiments described above, the frequency-region signal synthesis unit 311 specifically for：
According to sound conduction in the traveling wave delay model of basilar membrane, set voice signal corresponding with next in frequency domain
Plant or a variety of frequency domain values：Phase, frequency and amplitude.
On the basis of the various embodiments described above, the frequency-region signal synthesis unit 311 specifically for：
According to sound conduction in the traveling wave delay model of basilar membrane, basilar membrane group delay and feature frequency are fitted
The inverse ratio curve relation of rate；The phase spectrum and/or amplitude spectrum of voice signal are set according to the inverse ratio curve relation.
On the basis of the various embodiments described above, the frequency-region signal synthesis unit 311 specifically for：
The corresponding phase of voice signal and frequency relation are obtained to Frequency Domain Integration according to the curved line relation；And/or, to sound
The intensity of sound of the same amplitude of each set of frequency of message number.
The auditory brainstem response detection means that the various embodiments described above are provided can perform any embodiment institute of the present invention
The auditory brainstem response detection method of offer, possesses the execution corresponding functional module of auditory brainstem response detection method
And beneficial effect.
Note, above are only presently preferred embodiments of the present invention and institute's application technology principle.It will be appreciated by those skilled in the art that
The invention is not restricted to specific embodiment described here, can carry out for a person skilled in the art it is various it is obvious change,
Readjust and substitute without departing from protection scope of the present invention.Therefore, although the present invention is carried out by above example
It is described in further detail, but the present invention is not limited only to above example, without departing from the inventive concept, also
Other more equivalent embodiments can be included, and the scope of the present invention is determined by scope of the appended claims.
Claims (10)
1. a kind of auditory brainstem response detection method, it is characterised in that including：
Synthesis can compensate for the time domain frequency sweep voice signal of basilar membrane traveling wave delay；
Auditory system is stimulated using the time domain frequency sweep voice signal, auditory brainstem response ABR waveforms are obtained.
2. according to the method described in claim 1, it is characterised in that the synthesis can compensate for the delay of basilar membrane traveling wave
Time domain frequency sweep voice signal includes：
According to sound conduction in the traveling wave delay model of basilar membrane, the delay of each frequency of voice signal is adjusted in frequency domain, is obtained
To the frequency domain frequency sweep voice signal that can compensate for the delay of basilar membrane traveling wave；
Inverse transformation is carried out to the frequency domain frequency sweep voice signal and obtains the time domain frequency sweep voice signal.
3. method according to claim 2, it is characterised in that the traveling wave according to sound conduction in basilar membrane is prolonged
Slow model, the delay for adjusting each frequency of voice signal in frequency domain includes：
According to sound conduction basilar membrane traveling wave delay model, set voice signal corresponding following a kind of in frequency domain or
A variety of frequency domain values：Phase, frequency and amplitude.
4. method according to claim 2, it is characterised in that the traveling wave according to sound conduction in basilar membrane is prolonged
Slow model, the delay for adjusting each frequency of voice signal in frequency domain includes：
According to sound conduction in the traveling wave delay model of basilar membrane, basilar membrane group delay and characteristic frequency are fitted
Inverse ratio curve relation；
The phase spectrum and/or amplitude spectrum of voice signal are set according to the inverse ratio curve relation.
5. method according to claim 4, it is characterised in that described that voice signal is set according to the inverse ratio curve relation
Phase spectrum and/or amplitude spectrum include：
The corresponding phase of voice signal and frequency relation are obtained to Frequency Domain Integration according to the curved line relation；And/or, sound is believed
The intensity of sound of number each same amplitude of set of frequency.
6. a kind of auditory brainstem response detection means, it is characterised in that including：
Voice signal synthesis module, the time domain frequency sweep voice signal of basilar membrane traveling wave delay is can compensate for for synthesizing；
ABR waveform detection modules, for being stimulated using the time domain frequency sweep voice signal auditory system, obtain listening property brain
Dry reaction ABR waveforms.
7. device according to claim 6, it is characterised in that the voice signal synthesis module includes：
Frequency-region signal synthesis unit, for according to sound conduction basilar membrane traveling wave delay model, in frequency domain regulation sound
The delay of each frequency of message number, obtains can compensate for the frequency domain frequency sweep voice signal of basilar membrane traveling wave delay；
Inverse transformation block, the time domain frequency sweep voice signal is obtained for carrying out inverse transformation to the frequency domain frequency sweep voice signal.
8. device according to claim 7, it is characterised in that the frequency-region signal synthesis unit specifically for：
According to sound conduction basilar membrane traveling wave delay model, set voice signal corresponding following a kind of in frequency domain or
A variety of frequency domain values：Phase, frequency and amplitude.
9. device according to claim 7, it is characterised in that the frequency-region signal synthesis unit specifically for：
According to sound conduction in the traveling wave delay model of basilar membrane, basilar membrane group delay and characteristic frequency are fitted
Inverse ratio curve relation；The phase spectrum and/or amplitude spectrum of voice signal are set according to the inverse ratio curve relation.
10. device according to claim 9, it is characterised in that the frequency-region signal synthesis unit specifically for：
The corresponding phase of voice signal and frequency relation are obtained to Frequency Domain Integration according to the curved line relation；And/or, sound is believed
The intensity of sound of number each same amplitude of set of frequency.
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| CN112270991A (en) * | 2020-11-13 | 2021-01-26 | 深圳镭洱晟科创有限公司 | Hearing function evaluation earphone for hearing rehabilitation of old people and evaluation method thereof |
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| CN114503937A (en) * | 2021-12-29 | 2022-05-17 | 厦门大学 | Fish auditory characteristic measuring system based on auditory evoked potential acquisition and application thereof |
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| CN116350216A (en) * | 2023-03-31 | 2023-06-30 | 复旦大学附属眼耳鼻喉科医院 | Cochlear acoustic-electric stimulation interference recording and analyzing device |
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