CN107048412A - A kind of masticatory pattern product containing typeⅡ Collagen - Google Patents
A kind of masticatory pattern product containing typeⅡ Collagen Download PDFInfo
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- CN107048412A CN107048412A CN201710280989.XA CN201710280989A CN107048412A CN 107048412 A CN107048412 A CN 107048412A CN 201710280989 A CN201710280989 A CN 201710280989A CN 107048412 A CN107048412 A CN 107048412A
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Abstract
The invention provides a kind of masticatory pattern product containing typeⅡ Collagen, the component of the masticatory pattern product includes non denatured typeⅡ Collagen.The present invention also provides a kind of method of the masticatory pattern product containing typeⅡ Collagen prepared, and it includes：(1) allocate：Sterilized water is added into the typeⅡ Collagen prepared to stir, and when there is other auxiliary materials and/or effect component, all components are well mixed；(2) it is preforming：The mixture of the typeⅡ Collagen mixed well or allotment is poured into the effigurate grinding tool of tool；(3) it is freeze-dried：The mixture of preforming typeⅡ Collagen or allotment is placed into vacuum freeze drier to be dried.This masticatory pattern products taste containing typeⅡ Collagen that the present invention is provided is good, and inventors be surprised to learn that, when using the typeⅡ Collagen containing non denatured typeⅡ Collagen, the masticatory pattern product with expanded texture just resulted in is obtained by vacuum freeze drying.
Description
Technical field
The present invention relates to a kind of masticatory pattern product of collagen, more particularly to a kind of nozzle containing typeⅡ Collagen
Type product is chewed, especially containing non denatured typeⅡ Collagen.
Background technology
Collagen is a kind of important albumen composition in skin, bone, joint etc., is metazoan extracellular
The main constituents of medium.The typeⅡ Collagen being wherein made up of three identical collagenous fibres α chains is primarily present in soft
In bone tissue and in vitreum, therefore typeⅡ Collagen is by a kind of structural functionality nutrient regarding cartilage.
Have now been found that vivo immunization cell especially lymphocyte can become after non denatured typeⅡ Collagen is taken in
Immune tolerance, the reason for research has shown that immune tolerance is because containing epitope in the typeⅡ Collagen of intake.Antigen
Determine base be antigen a special structural units, can by antibody recognize and bind, when antibody be tied to pathogenic microorganism or
During macromolecular, antibody can not recognize whole organism or material, but can recognize mark and bind it.Active antigens determine base quilt
It is bundled in aggregate nodules and exists as a tissue in small intestine, goes to stimulate immunocyte, information transmission molecule such as cell factor
Disinthibite inflammation, such as arthritis are secreted with Proliferation, Differentiation chemotactic factor (CF) and suppression cell is participated in.
Arthritis is one of most common chronic disease, is known as " the No.1 crippling disease in the world ", is mainly shown as pass
Save pain, swelling and activity difficult, joint deformity is may occur in which when serious.Most common in such disease is osteoarthritis, rheumatic
Arthritis and ankylosing spondylitis, wherein rigid spine are apt to occur in 15-30 Sui young man, and other two kinds are mainly in person in middle and old age
People, so arthritis is not only the disease of the elderly, also has started to extend " preference sitting crowd " to young man, the current whole world is closed
The scorching patient of section has 3.55 hundred million people, just has 1 people to suffer from arthritis in some stage in all one's life in Asia, every 6 people, relevant
Data shows that arthritis is about 13% in the total incidence of China, and current arthritis number has more than 100,000,000, and number is also
Constantly increasing.
At home and abroad have the typeⅡ Collagen health products of some prevention and treatment joint diseases, formula on the market at present
Substantially collagen, ammonia sugar and chondroitin sulfate, it is universal because mouthfeel is bad and make the formulation of capsule or tablet so as to
People eat, not yet occur it is a kind of can directly chewing mouthfeel it is good and have expanded mouthfeel typeⅡ Collagen product.
The content of the invention
There is provided a kind of masticatory pattern in good taste containing typeⅡ Collagen in order to overcome the defect of prior art by the present invention
Product.
Therefore, the invention provides a kind of masticatory pattern product containing typeⅡ Collagen, it is characterised in that the masticatory pattern
The component of product includes non denatured typeⅡ Collagen.
The present invention also provides a kind of method of the masticatory pattern product containing typeⅡ Collagen prepared, it is characterised in that
This method includes：(1) allocate：Sterilized water is added into the typeⅡ Collagen prepared to stir, and there are other auxiliary materials
And/or during effect component, all components are well mixed；(2) it is preforming：By the mixed of the typeⅡ Collagen mixed well or allotment
Compound is poured into the effigurate grinding tool of tool；(3) it is freeze-dried：By preforming typeⅡ Collagen or the mixing of allotment
Thing is placed into vacuum freeze drier and is dried.
This masticatory pattern product containing typeⅡ Collagen that the present invention is provided not only contains the Collagen Type VI egg of non denatured II
In vain, it is and in good taste.
Present inventor has been surprisingly found that, when using the typeⅡ Collagen containing non denatured typeⅡ Collagen,
The masticatory pattern product with expanded texture just resulted in is obtained by vacuum freeze drying.Especially, inventor is had found when II
When the content of non denatured typeⅡ Collagen is more than 0.5 weight % in collagen type, expansion effect is just very good.It is more outstanding
It is, when using when the containing non denatured collagen of method preparation in the application, the expansion effect of acquisition is very perfect.
Present inventor also found, can be added in the typeⅡ Collagen containing non denatured typeⅡ Collagen
Other functional components, can equally prepare the masticatory pattern product with expanded texture.
Masticatory pattern product containing typeⅡ Collagen, simple to operation, the product of preparation are prepared using the inventive method
It is in good taste, and variously-shaped product can be prepared.
Embodiment
The invention provides a kind of masticatory pattern product containing typeⅡ Collagen, it is characterised in that the masticatory pattern product
Component include non denatured typeⅡ Collagen.
Present inventor has been surprisingly found that, when the content of the non denatured typeⅡ Collagen in typeⅡ Collagen reaches
During finite concentration, it becomes possible to easily obtain the masticatory pattern product of expanded texture.Therefore, in one kind preferred embodiment
In, in the masticatory pattern product, the content of the non denatured typeⅡ Collagen is at least 0.5 weight %, implements another
In mode, the content of the non denatured typeⅡ Collagen is 2-5 weight %.
Present inventor also found when using following methods prepare typeⅡ Collagen when, II Collagen Type VI egg of acquisition
Bai Chundu is high, and the non denatured typeⅡ Collagen containing high content, and such collagen is very suitable for preparing expanded matter
The masticatory pattern product on ground.Therefore, in another preferred embodiment, the typeⅡ Collagen is to make by the following method
It is standby：This method comprises the following steps successively：Degreasing, sterilization, homogenate, enzymolysis, filtering, desalination；Wherein, in the enzymolysis step
In：The pH of the slurry obtained in refining step is adjusted to 2.5~8.5, adds the 0.001%-2%'s of cartilage weight
Enzyme, 1/20~1/500 pawpaw and/or pineapple low temperature for adding cartilage weight filters the clear liquid of acquisition after squeezing the juice, and enzymolysis 12~
48h, hydrolysis temperature is 25-50 DEG C；The enzyme is preferably pepsin, subtilopeptidase A, alkali protease, metalloprotein
One or more in enzyme.
In another preferred embodiment, the consumption of institute's enzyme is the 0.5-2% of cartilage weight, pawpaw and/or pineapple
Low temperature filters the clear liquid of acquisition consumption after squeezing the juice is the 1/20-1/50 of cartilage weight, and enzymolysis time is 12~20h, enzymolysis temperature
25~40 DEG C of degree.
In another preferred embodiment, after the clear liquid of addition is pawpaw and pineapple low temperature is squeezed the juice filtering obtain it is mixed
Clear liquid is closed, wherein, the weight ratio of pawpaw and pineapple is 1-10：1, preferably 3-6：1.
In another preferred embodiment, wherein,
Degreasing：With certain density degreasing agent immersion cartilage fourth shape thing 0.2h~6h, then cleaned with water to cleaning
The pH of water to 5.5~8.5
Sterilization：With the cartilage fourth shape thing 1~3 time after finite concentration medicining liquid dipping degreasing, then cleaned with water to cartilage
Fourth shape thing is tasteless；
Homogenate：Cartilage fourth shape thing after sterilization is subjected to homogenized, the granularity of cartilage is 50~300 mesh after homogenate；
Filtering：Filtered using 5~100 eye mesh screens, remove large particulate matter in solution, collect filtered fluid；
Desalination：Filtered fluid will be collected to clean repeatedly, centrifugation removes cleaning fluid, until centrifuged supernatant electrical conductivity≤
300us/cm。
In order to obtain more preferable health-care effect, the masticatory pattern product of the application also includes other effect components.Therefore, another
It is a kind of preferred embodiment in, the component of the masticatory pattern product also includes other effect components, other effect components choosings
From vitamin, ammonia sugar, curcuma powder, Radix Notoginseng powder, red date powder, natto powder, calcium, zinc, resveratrol, radix tarxaci stem-leaf extract,
One or more in polysaccharide, albumen, peptide, glucoside.
In another preferred embodiment, the masticatory pattern product has the mouthfeel of dilated food.Prepare dilated food,
Absorption is not only improved, is also easy to that variously-shaped, such as circular, square, oval, triangle, star, various flower-shapes etc. is made.
In another preferred embodiment, the masticatory pattern product is prepared by the following method：
(1) allocate：Into the typeⅡ Collagen prepared add sterilized water stir, exist other auxiliary materials and/
Or during effect component, all components are well mixed；
(2) it is preforming：The mixture of the typeⅡ Collagen mixed well or allotment is poured into the effigurate grinding tool of tool
In；
(3) it is freeze-dried：The mixture of preforming typeⅡ Collagen or allotment is placed into vacuum freeze drying
Machine is dried.
For the ease of guaranteeing the quality and transporting, it is preferable that sealer is packed after freeze-drying.
The present invention also provides a kind of method for preparing the masticatory pattern product containing typeⅡ Collagen that the present invention is provided, its
It is characterised by,
(1) allocate：Into the typeⅡ Collagen prepared add sterilized water stir, exist other auxiliary materials and/
Or during effect component, all components are well mixed；
(2) it is preforming：The mixture of the typeⅡ Collagen mixed well or allotment is poured into the effigurate grinding tool of tool
In.
(3) it is freeze-dried：The mixture of preforming typeⅡ Collagen or allotment is placed into vacuum freeze drying
Machine is dried.
For the ease of guaranteeing the quality and transporting, it is preferable that sealer is packed after freeze-drying.
Described freezing dry process can be carried out according to the freezing curve of design, can be stopped when final vacuum is less than 1pa.
The temperature of freeze-drying is less than 30 DEG C, and the sale at reduced prices size of freeze-drying can be most long variously-shaped less than 15mm.
Embodiment 1
(1) pre-process：Chick sternal cartilage 3.5kg is chosen, chicken, manadesma and red bone on cartilage, Ran Houli are removed after defrosting
3*3mm fourth shape is cut into dicer.
(2) degreasing：With the Na of 0.01% concentration eventually2CO3With 2%NaCl mixed defatting agent solution 7kg, normal temperature degreasing 4h,
Cleaned after degreasing draining with purified water to pH6.5.
(3) sterilize：Plus concentration 400ppm liquor natrii hypochloritises start sterilization, sterilize 2 times, each 12h, sterilization is used after terminating
Purified water is cleaned to without sterilization also smell and detected without chlorine residue, and pH is controlled in 6.5-7.0.
(4) it is homogenized：The cartilage fourth shape thing of step (3) processing is added into 6kg purified waters, cartilage is worn into 100- with colloid mill
200 mesh.
(5) digest：The slurries pH that step (4) is obtained is adjusted to 2.5, adds 70 grams of pepsins, is added 60 low temperature and is squeezed
Filtered after juice acquisition fresh pawpaw clear liquid and 10g low temperature squeeze the juice after filter the fresh pineapple clear liquid of acquisition, in temperature, 25 DEG C are entered
Row enzymolysis 20h.
(6) filter：Filtered using 5 eye mesh screens, remove large particulate matter in solution, collect filtered fluid.
(7) desalination：Filtered fluid is collected by being cleaned multiple times, until centrifuged supernatant electrical conductivity is less than 300us/cm.
Then after addition 3kg sterilized water stirs, pour into triangular mould, be freeze-dried, obtain expanded three
Angular typeⅡ Collagen product.
Embodiment 2
(1) pre-process：Chick sternal cartilage 3.5kg is chosen, chicken, manadesma and red bone on cartilage, Ran Houli are removed after defrosting
3*3mm fourth shape is cut into dicer.
(2) degreasing：With the Na of 0.01% concentration eventually2CO3With 2%NaCl mixed defatting agent solution 7kg, normal temperature degreasing 4h,
Cleaned after degreasing draining with purified water to pH6.5.
(3) sterilize：Plus concentration 400ppm liquor natrii hypochloritises start sterilization, sterilize 2 times, each 12h, sterilization is used after terminating
Purified water is cleaned to without sterilization also smell and detected without chlorine residue, and pH is controlled in 6.5-7.0.
(4) it is homogenized：The cartilage fourth shape thing of step (3) processing is added into 6kg purified waters, cartilage is worn into 100- with colloid mill
200 mesh.
(5) digest：The slurries pH that step (4) is obtained is adjusted to 2.5, adds 70 grams of pepsins, is added 60 low temperature and is squeezed
Filtered after juice acquisition fresh pawpaw clear liquid and 10g low temperature squeeze the juice after filter the fresh pineapple clear liquid of acquisition, in temperature, 25 DEG C are entered
Row enzymolysis 20h.
(6) filter：Filtered using 5 eye mesh screens, remove large particulate matter in solution, collect filtered fluid.
(7) desalination：Filtered fluid is collected by being cleaned multiple times, until centrifuged supernatant electrical conductivity is less than 300us/cm.
Then after addition 3kg sterilized water stirs, 150g dextrin, 20g peanut sprouts extract, 60g ammonia is added
Base glucosamine salt hydrochlorate, 10g red date powders, 3g curcuma powders, then stir, and pour into pentalpha mould, freeze-drying, obtain
Obtain expanded pentalpha typeⅡ Collagen product.
Embodiment 3
(1) pre-process：Fresh duck chest cartilage 20kg is chosen, duck, manadesma and red bone on cartilage are removed after defrosting, then
About 2mm*2mm fourth shape is cut into using dicer
(2) degreasing：With final concentration of 0.01% NaOH and 0.9% KCl solution 200kg, normal temperature degreasing 6h, Ran Houyong
Purified water cleans pH6.0.
(3) sterilize：Plus concentration 500ppm liquor natrii hypochloritises (hydrogen peroxide containing 100ppm) start to sterilize, sterilization 3 times, often
Secondary 6h, sterilization is cleaned to without sterilization also smell with purified water after terminating and detected without chlorine residue, and pH is controlled in 6.5-7.0.
(4) it is homogenized：40kg purified water is added in the cartilage fourth shape thing handled to step (3), cartilage is ground with colloid mill
Into about 100-200 mesh.
(5) digest：The slurries pH that step (4) is obtained is adjusted to 8.5, plus 0.2 gram of alkali protease, adds 1kg low temperature
The fresh pineapple clear liquid of acquisition is filtered after squeezing the juice, in temperature 50 C, enzymolysis 12h is carried out.
(6) filter：Filtered using 100 eye mesh screens, remove large particulate matter in solution, collect filtered fluid.
(7) desalination：Filtered fluid is collected by being cleaned multiple times, until centrifuged supernatant electrical conductivity is less than 300us/cm.
Then add 25kg sterilized water stir after, add 5kg dextrin, vitamin C 10g, calciferol g,
Plus zinc gluconate 1g, gluconic acid- ca 1g, pour into square shape mould, be freeze-dried, obtain expanded square II type
Collagen product.
Embodiment 4
(1) pre-process：Chick sternal cartilage 20kg is chosen, chicken, manadesma and red bone on cartilage are removed after defrosting, is then utilized
Dicer is cut into 3*3mm fourth shape.
(2) degreasing：With whole 0.2%NaOH and 0.6%NaCl solution 100kg, normal temperature degreasing 0.2h, purified water is then used
Clean pH6.0.
(3) sterilize：Plus concentration 2000ppm liquor natrii hypochloritises start sterilization, sterilize 1 time, each 0.2h, after sterilization terminates
Cleaned to without sterilization also smell and detected without chlorine residue with purified water, pH is controlled in 6.5-7.0.
(4) it is homogenized：50kg purified water is added in the cartilage fourth shape thing handled to step (3), cartilage is ground with colloid mill
Into 100-200 mesh.
(5) digest：The slurries pH that step (4) is obtained is adjusted to 7.0, plus 20g subtilopeptidase As, adds 200g low
Temperature filtered after squeezing the juice acquisition fresh pawpaw clear liquid and 20g low temperature squeeze the juice after filter the fresh pineapple clear liquid of acquisition, in temperature 40
DEG C carry out enzymolysis 24h.
(6) filter：Filtered using 50 eye mesh screens, remove large particulate matter in solution, collect filtered fluid.
(7) desalination：Filtered fluid is collected by being cleaned multiple times, until centrifuged supernatant electrical conductivity is less than 300us/cm.
Then after addition 20kg sterilized water stirs, 1kg dextrin is added, 200g is poured into cartoon shaped mould, freezed
Dry, obtain expanded cartoon shaped typeⅡ Collagen product.
Embodiment 5
(1) pre-process：Chick sternal cartilage 70kg is chosen, chicken, manadesma and red bone on cartilage are removed after defrosting, is then utilized
Dicer is cut into 3*3mm fourth shape.
(2) degreasing：With whole 0.15%KOH and 0.3%KCl solution 140kg, normal temperature degreasing 2h is then clear with purified water
Wash pH6.0.
(3) sterilize：Plus concentration 100ppm liquor natrii hypochloritises (hydrogen peroxide containing 1000ppm) start to sterilize, sterilization 2 times, often
Secondary 0.5h, sterilization is cleaned to without sterilization also smell with purified water after terminating and detected without chlorine residue, and pH is controlled in 6.5-7.0.
(4) it is homogenized：140kg purified water is added in the cartilage fourth shape thing handled to step (3), cartilage is ground with colloid mill
Into 100-200 mesh.
(5) digest：The slurries pH that step (4) is obtained is adjusted to 7.5, plus 21g metalloproteinases, is added 700g low temperature and is squeezed
The fresh pineapple clear liquid that acquisition is filtered after juice carries out enzyme 16h for 40 DEG C in temperature.
(6) filter：Filtered using 50 eye mesh screens, remove large particulate matter in solution, collect filtered fluid.
(7) desalination：Filtered fluid is collected by being cleaned multiple times, until centrifuged supernatant electrical conductivity is less than 300us/cm.
Then after addition 60kg purified water stirs, natto powder 1kg, red date powder 1kg, dandelion extract are added
200g, resveratrol extract 50g, are poured into ellipse mould, freeze-drying, obtain expanded ellipse typeⅡ Collagen
Product.
Embodiment 6
1) pre-process：Chick sternal cartilage 30kg is chosen, chicken, manadesma and red bone on cartilage are removed after defrosting, is then utilized
Dicer is cut into 5*5mm fourth shape.
(2) degreasing：With whole 0.05%NaOH and 0.1%KCl solution 90kg, normal temperature degreasing 1h is then clear with purified water
Wash pH6.0.
(3) sterilize：Plus concentration 300ppm liquor natrii hypochloritises 60kg starts sterilization, sterilize 2 times, each 8h, sterilization terminates
Cleaned to without sterilization also smell and detected without chlorine residue with purified water afterwards, pH is controlled in 6.5-7.0.
(4) it is homogenized：70kg purified water is added in the cartilage fourth shape thing handled to step (3), cartilage is ground with colloid mill
Into 100-200 mesh.
(5) digest：The slurries pH that step (4) is obtained is adjusted to 3.0, plus 150g pepsins, is added 135g low temperature and is squeezed
Filtered after juice acquisition fresh pawpaw clear liquid and 45g low temperature squeeze the juice after filter the fresh pineapple clear liquid of acquisition, in temperature, 25 DEG C are entered
Row enzyme 16h.
(6) filter：Filtered using 50 eye mesh screens, remove large particulate matter in solution, collect filtered fluid.
(7) desalination：Filtered fluid is collected by being cleaned multiple times, until centrifuged supernatant electrical conductivity is less than 300us/cm.
Then add 20kg purified water stir after, add almond peptide 500g, oyster peptide 200g, Radix Notoginseng powder 200g,
Lentinan 300g, is poured into round mould, freeze-drying, obtains expanded round typeⅡ Collagen product.
Embodiment 7
1) pre-process：Ox cartilage 5kg is chosen, beef, manadesma and red bone on cartilage are removed after defrosting, then using dicing
Fourth shape of the machine-cut into 5*5mm.
(2) degreasing：With whole 0.3%NaOH and 1%NaCl solution 20kg, normal temperature degreasing 3h, then cleaned with purified water
pH6.0。
(3) sterilize：Plus concentration 500ppm liquor natrii hypochloritises 10kg starts sterilization, sterilize 3 times, each 1.5h, sterilization knot
Shu Houyong purified waters are cleaned to without sterilization also smell and detected without chlorine residue, and pH is controlled in 6.5-7.0.
(4) it is homogenized：10kg purified water is added in the cartilage fourth shape thing handled to step (3), cartilage is ground with colloid mill
Into 100-200 mesh.
(5) digest：The slurries pH that step (4) is obtained is adjusted to 3.0, plus 75g pepsins, is added 25g low temperature and is squeezed the juice
Filter afterwards acquisition fresh pawpaw clear liquid and 25g low temperature squeeze the juice after filter the fresh pineapple clear liquid of acquisition, in 25 DEG C of progress of temperature
Enzyme 20h.
(6) filter：Filtered using 50 eye mesh screens, remove large particulate matter in solution, collect filtered fluid.
(7) desalination：Filtered fluid is collected by being cleaned multiple times, until centrifuged supernatant electrical conductivity is less than 300us/cm.
Then add 5kg sterilized water stir after, add farnoquinone 10g, ginseng glucoside 5g, red date powder 30g,
The oligomeric Gly-His-Lys 30g of collagen, is poured into heart-shaped mould, freeze-drying, obtains expanded heart-shaped typeⅡ Collagen product.
Claims (10)
1. a kind of masticatory pattern product containing typeⅡ Collagen, it is characterised in that the component of the masticatory pattern product includes non-become
Property typeⅡ Collagen.
2. the masticatory pattern product according to claim 1 containing typeⅡ Collagen, it is characterised in that in the masticatory pattern
In product, the content at least 0.5 weight % of the non denatured typeⅡ Collagen.
3. the masticatory pattern product according to claim 1 containing typeⅡ Collagen, it is characterised in that
The typeⅡ Collagen is to be prepared by the following method：This method comprises the following steps successively：Degreasing, sterilization, homogenate,
Enzymolysis, filtering, desalination；Wherein, in the enzymolysis step：The pH of the slurry obtained in refining step is adjusted to 2.5
~8.5, the 0.001%-2% of cartilage weight enzyme is added, 1/20~1/500 pawpaw and/or pineapple of cartilage weight is added
Low temperature filters the clear liquid of acquisition after squeezing the juice, digest 12~48h, and hydrolysis temperature is 25-50 DEG C；The enzyme be preferably pepsin,
One or more in subtilopeptidase A, alkali protease, metalloproteinases.
4. a kind of masticatory pattern product of II collagen types according to claim 3, it is characterised in that the consumption of institute's enzyme is
The 0.5-2% of cartilage weight, pawpaw and/or pineapple low temperature filter the clear liquid of acquisition consumption after squeezing the juice is the 1/ of cartilage weight
20-1/50, enzymolysis time is 12~20h, 25~40 DEG C of hydrolysis temperature.
5. a kind of masticatory pattern product of II collagen types according to claim 3, it is characterised in that the clear liquid of addition is
Pawpaw and pineapple low temperature filter the mixing clear liquid of acquisition after squeezing the juice, wherein, the weight ratio of pawpaw and pineapple is 1-10：1, be preferably
3-6：1.
6. a kind of masticatory pattern product of II collagen types according to claim 3-5 any one, it is characterised in that its
In,
Degreasing：Cartilage fourth shape thing 0.2h~6h is soaked with certain density degreasing agent, the water then cleaned with water to cleaning
PH to 5.5~8.5
Sterilization：With the cartilage fourth shape thing 1~3 time after finite concentration medicining liquid dipping degreasing, then cleaned with water to cartilage fourth shape
Thing is tasteless；
Homogenate：Cartilage fourth shape thing after sterilization is subjected to homogenized, the granularity of cartilage is 50~300 mesh after homogenate；
Filtering：Filtered using 5~100 eye mesh screens, remove large particulate matter in solution, collect filtered fluid；
Desalination：Filtered fluid will be collected to clean repeatedly, centrifugation removes cleaning fluid, until centrifuged supernatant electrical conductivity≤300us/
cm。
7. a kind of masticatory pattern product of the cartilage extracts of collagen type containing II according to claim 1, its feature exists
In the component of the masticatory pattern product also includes other effect components, and other effect components are selected from vitamin, ammonia sugar, turmeric
In powder, Radix Notoginseng powder, red date powder, natto powder, calcium, zinc, resveratrol, radix tarxaci stem-leaf extract, polysaccharide, albumen, peptide, glucoside
One or more.
8. a kind of masticatory pattern product of collagen type containing II according to any one in claim 1-5 and 7, its feature
It is, the masticatory pattern product has the mouthfeel of dilated food.
9. a kind of masticatory pattern product of collagen types of II containing non denatured according to claim 8, it is characterised in that the nozzle
The type product of chewing is prepared by the following method：
(1) allocate：Sterilized water is added into the typeⅡ Collagen prepared to stir, and there is other auxiliary materials and/or work(
When imitating component, all components are well mixed；
(2) it is preforming：The mixture of the typeⅡ Collagen mixed well or allotment is poured into the effigurate grinding tool of tool；
(3) it is freeze-dried：The mixture of preforming typeⅡ Collagen or allotment is placed into vacuum freeze drier to enter
Row drying.
10. a kind of method of the masticatory pattern product containing typeⅡ Collagen prepared according to claim any one of 1-9,
Characterized in that, this method comprises the following steps：
(1) allocate：Sterilized water is added into the typeⅡ Collagen prepared to stir, and there is other auxiliary materials and/or work(
When imitating component, all components are well mixed；
(2) it is preforming：The mixture of the typeⅡ Collagen mixed well or allotment is poured into the effigurate grinding tool of tool；
(3) it is freeze-dried：The mixture of preforming typeⅡ Collagen or allotment is placed into vacuum freeze drier to enter
Row drying.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112106939A (en) * | 2020-09-25 | 2020-12-22 | 康洛信(广东)生物科技有限公司 | Collagen filling material for improving mouthfeel and artificial meat product containing same |
| WO2022226731A1 (en) * | 2021-04-26 | 2022-11-03 | 北京盛美诺生物技术有限公司 | Pretreatment method for quantitative detection of undenatured type ii collagen in collagen product or cartilage, and application |
| EP4084868A4 (en) * | 2019-12-27 | 2024-01-31 | Suntory Holdings Ltd | Food or beverage composition containing peptide and/or salt thereof, production method thereof, use of hydrolyzed collagen type ii, composition for inhibiting bone resorption, and use of chicken extract |
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