CN107041893A - A kind of phytic acid mixture and burn-treating liquid - Google Patents
A kind of phytic acid mixture and burn-treating liquid Download PDFInfo
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- CN107041893A CN107041893A CN201611039336.4A CN201611039336A CN107041893A CN 107041893 A CN107041893 A CN 107041893A CN 201611039336 A CN201611039336 A CN 201611039336A CN 107041893 A CN107041893 A CN 107041893A
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- Prior art keywords
- phytic acid
- burn
- treating liquid
- mixture
- phosphoric acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/42—Phosphorus; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
- A61K31/6615—Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Invention provides the burn-treating liquid of a kind of phytic acid mixture and application the phytic acid mixture.The phytic acid mixture is the mixture of phytic acid and phosphoric acid, wherein, the molar ratio range of the phytic acid and the phosphoric acid is in (0.075~1.5):Between (0.1~9.8).In the present invention, mixed by the phytic acid of certain pure with phosphoric acid according to specific molar ratio, coordinate the selection of particular active agent simultaneously, while so that the burn-treating liquid obtained has promotion healing burn wound, also have and recover skin lines, the colour of skin, pore and other effects, reach preventing from scar, do not influence the purpose of hair growth.
Description
Technical field
The present invention relates to the boiling hot burn class product scope of skin, more particularly to a kind of phytic acid mixture and using the phytic acid mixture
Burn-treating liquid.
Background technology
Burn may be caused by different external heat source contact skin, such as flame, chemicals, friction, electric current, radiation
With high temperature etc..Therefore burn can also be divided into chemical burn, electric burn, radiation burn and hydrothermal solution burn etc. accordingly.Can during burn
The lactic acid production increase seen in blood, the pH value reduction of arteriovenous blood, with the exacerbation of tissue capillary dysfunction, anoxemia
Disease is also increased weight.Burn can then be in peril of one's life when reaching more than 1/3rd of total body surface area.According to the body surface gross area of burn,
Whether injure the anatomical area at key, the factor such as patient age and related injury, will burn grade classification be severe burn, in
Degree burn and mild burn.
At present, the treatment for burn is mainly smearing and takes antibiotic medicine, and is formulated simple Chinese medicinal ointment, general
All over that can accomplish to prevent infection, promote effect of wound healing.
Although however, the burn-treating liquid generally used at present can cicatrize a wound, but still presence can not recover skin
The problems such as lines, the colour of skin, pore, easily cause and stay the sequelae such as scar, influence hair growth.
It would therefore be desirable to a kind of new burn-treating liquid, to solve the technical problem that presently, there are
The content of the invention
It is an object of the invention to provide a kind of new burn-treating liquid, the skin tissue's cytothesis for scalding burnt degree can be made,
Recover the external appearance characteristic of skin skin, that is, recover the skin appearance features, not preventing from scar, shadow such as lines, the colour of skin, the pore of skin
Ring hair growth.
In order to realize the effect above, present invention firstly provides a kind of phytic acid mixture, for burn-treating liquid.The phytic acid mixing
Thing is the mixture of phytic acid and phosphoric acid, wherein, the molar ratio range of the phytic acid and the phosphoric acid is in (0.075~1.5):(0.1
~9.8) between.
In an embodiment of the present invention, the phytic acid is the commercial compound represented with molecular formula I：Formulas I：H24C6P6O18。
In an embodiment of the present invention, the phosphoric acid is the commercial compound represented with molecular formula II：Formula II：H3PO4。
In an embodiment of the present invention, the purity of the phytic acid is 50~95%, preferably 50%3.
The present invention also provides a kind of burn-treating liquid, includes any one above-mentioned phytic acid mixture.Wherein, the burn-treating liquid is also wrapped
Include water so that the quality of the phytic acid in the phytic acid mixture is the 0.3~55% of the gross mass of the burn-treating liquid.In the present invention
In one embodiment, the quality of the phytic acid in the phytic acid mixture is the 45~55% of the gross mass of the burn-treating liquid.
In an embodiment of the present invention, the burn-treating liquid also includes at least one activating agent, and the quality of the activating agent is
The 0.01~0.05% of the burn-treating liquid gross mass.
In an embodiment of the present invention, the conventional dispersant of the activating agent selection, such as, but not limited to biocolloid point
Powder.
Those skilled in the art should know that unless otherwise specified, of the present invention is actually commercially available prod.
Applicants experimentally found that, the purity of phytic acid has certain influence for therapeutic effect, and when purity improve to
Therapeutic effect is obvious when 50%.Although high purity is also improved for therapeutic effect again, increase rate is not obvious.Therefore,
For taking into account the consideration of therapeutic effect and cost control, applicant have determined that use purity for 50~95% phytic acid, and preferably
50%.
In the present invention, mixed by the phytic acid of certain pure with phosphoric acid according to specific molar ratio, while coordinating specific work
Property agent selection so that the burn-treating liquid of acquisition have promote healing burn wound while, also with recover skin lines, skin
Color, pore and other effects, reach preventing from scar, do not influence the purpose of hair growth.
Brief description of the drawings
Fig. 1 is the therapeutic effect figure of burn-treating liquid of the present invention.
Embodiment
Hereinafter, with reference to embodiment, the technology to the present invention is described in detail.It is appreciated that the various real in detail below
The mode of applying is only used for helping skilled in the art to understand the present invention, rather than limitation of the present invention.
Embodiment 1
In the present embodiment there is provided a kind of burn-treating liquid, including phytic acid mixture and water.Wherein, the phytic acid mixture is
The mixture of phytic acid and phosphoric acid, wherein, the mol ratio of the phytic acid and phosphoric acid is 0.15:1.2, also, in the burn-treating liquid,
The quality of the phytic acid accounts for the 52% of the burn-treating liquid gross mass.
The phytic acid is the commercial compound represented with molecular formula I：Formulas I：H24C6P6O18.The phosphoric acid is with molecular formula II
The commercial compound of expression：Formula II：H3PO4。
The purity of the phytic acid is 90%.
The preparation method of the burn-treating liquid is：The phytic acid, phosphoric acid are well mixed with water under normal temperature and pressure.
Embodiment 2
In the present embodiment there is provided a kind of burn-treating liquid, including phytic acid mixture and water.Wherein, the phytic acid mixture is
The mixture of phytic acid and phosphoric acid, wherein, the mol ratio of the phytic acid and phosphoric acid is 0.75:3.6, also, in the burn-treating liquid,
The quality of the phytic acid accounts for the 48% of the burn-treating liquid gross mass.
The phytic acid is the commercial compound represented with molecular formula I：Formulas I：H24C6P6O18.The phosphoric acid is with molecular formula II
The commercial compound of expression：Formula II：H3PO4.The purity of the phytic acid is 80%.
The preparation method of the burn-treating liquid is：The phytic acid, phosphoric acid are well mixed with water under normal temperature and pressure.
Embodiment 3
In the present embodiment there is provided a kind of burn-treating liquid, including phytic acid mixture, water and activating agent.Wherein, the phytic acid is mixed
Compound is the mixture of phytic acid and phosphoric acid, wherein, the mol ratio of the phytic acid and phosphoric acid is 1.2:6.5, also, in the burn
In liquid, the quality of the phytic acid accounts for the 15% of the burn-treating liquid gross mass, and the quality of the activating agent is the total matter of the burn-treating liquid
The 0.01~0.05% of amount.The conventional dispersant of the activating agent selection, such as, but not limited to biocolloid dispersant.
The phytic acid is the commercial compound represented with molecular formula I：Formulas I：H24C6P6O18.The phosphoric acid is with molecular formula II
The commercial compound of expression：Formula II：H3PO4.The purity of the phytic acid is 60%.
The preparation method of the burn-treating liquid is：The phytic acid, phosphoric acid are well mixed with water under normal temperature and pressure.
Embodiment 4
In the present embodiment there is provided a kind of burn-treating liquid, including phytic acid mixture, water and activating agent.Wherein, the phytic acid is mixed
Compound is the mixture of phytic acid and phosphoric acid, wherein, the mol ratio of the phytic acid and phosphoric acid is 1.0:5.0, also, in the burn
In liquid, the quality of the phytic acid accounts for the 35% of the burn-treating liquid gross mass, and the quality of the activating agent is the total matter of the burn-treating liquid
The 0.01~0.05% of amount.The conventional dispersant of the activating agent selection, such as, but not limited to biocolloid dispersant.
The phytic acid is the commercial compound represented with molecular formula I：Formulas I：H24C6P6O18.The phosphoric acid is with molecular formula II
The commercial compound of expression：Formula II：H3PO4.The purity of the phytic acid is 55%.
The preparation method of the burn-treating liquid is：The phytic acid, phosphoric acid are well mixed with water under normal temperature and pressure.
Embodiment 5
In the present embodiment there is provided a kind of burn-treating liquid, including phytic acid mixture, water and activating agent.Wherein, the phytic acid is mixed
Compound is the mixture of phytic acid and phosphoric acid, wherein, the mol ratio of the phytic acid and phosphoric acid is 1.0:8.0, also, in the burn
In liquid, the quality of the phytic acid accounts for the 5% of the burn-treating liquid gross mass, and the quality of the activating agent is the burn-treating liquid gross mass
0.01~0.05%.The conventional dispersant of the activating agent selection, such as, but not limited to biocolloid dispersant.
The phytic acid is the commercial compound represented with molecular formula I：Formulas I：H24C6P6O18.The phosphoric acid is with molecular formula II
The commercial compound of expression：Formula II：H3PO4.The purity of the phytic acid is 65%.
The burn-treating liquid of above-described embodiment 1~5 is applied in burn case by applicant, and effect is see accompanying drawing 1.Can by Fig. 1
To be apparent from, burn-treating liquid effect of the present invention is obvious.
The present invention is been described by by above-mentioned related embodiment, but above-described embodiment is only the example for implementing the present invention.
It must be noted that, it has been disclosed that embodiment be not limiting as the scope of the present invention.On the contrary, being contained in the spirit of claims
And the modification of scope and impartial setting are included in the scope of the present invention.
Claims (5)
1. a kind of phytic acid mixture, for burn-treating liquid, it is characterised in that the phytic acid mixture is the mixing of phytic acid and phosphoric acid
Thing, wherein, the molar ratio range of the phytic acid and the phosphoric acid is in (0.075~1.5):Between (0.1~9.8).
2. phytic acid mixture as claimed in claim 1, wherein, the phytic acid is represented with following molecular formula I：
H24C6P6O18Formulas I.
3. phytic acid mixture as claimed in claim 1, it is characterised in that the purity of the phytic acid is 50~95%.
4. a kind of burn-treating liquid, includes the phytic acid mixture described in claim 1, it is characterised in that the burn-treating liquid also includes water,
Wherein, the quality of the phytic acid in the phytic acid mixture is the 0.3~55% of the gross mass of the burn-treating liquid.
5. burn-treating liquid as claimed in claim 4, it is characterised in that also including activating agent, the quality of the activating agent is described
The 0.01~0.05% of the gross mass of burn-treating liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611039336.4A CN107041893A (en) | 2016-11-21 | 2016-11-21 | A kind of phytic acid mixture and burn-treating liquid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611039336.4A CN107041893A (en) | 2016-11-21 | 2016-11-21 | A kind of phytic acid mixture and burn-treating liquid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107041893A true CN107041893A (en) | 2017-08-15 |
Family
ID=59543769
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611039336.4A Pending CN107041893A (en) | 2016-11-21 | 2016-11-21 | A kind of phytic acid mixture and burn-treating liquid |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1069651A (en) * | 1991-12-09 | 1993-03-10 | 贺建龙 | The production method of quick effect wound-healing |
| CN1843366A (en) * | 2006-01-26 | 2006-10-11 | 陈兴祥 | Burn-treating liquid |
| CN102225072A (en) * | 2011-06-15 | 2011-10-26 | 西安交通大学 | Sodium humate skin external preparation for promoting wound healing |
| CN102942588A (en) * | 2012-11-16 | 2013-02-27 | 深圳市沙特尔工业材料有限公司 | Preparation method of colorless phytic acid |
| CN103446290A (en) * | 2013-07-12 | 2013-12-18 | 六枝特区人民医院 | Burn tincture as well as preparation method and application thereof |
| CN103833787A (en) * | 2014-01-25 | 2014-06-04 | 深圳市沙特尔工业材料有限公司 | Preparation method for phytic acid |
-
2016
- 2016-11-21 CN CN201611039336.4A patent/CN107041893A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1069651A (en) * | 1991-12-09 | 1993-03-10 | 贺建龙 | The production method of quick effect wound-healing |
| CN1843366A (en) * | 2006-01-26 | 2006-10-11 | 陈兴祥 | Burn-treating liquid |
| CN102225072A (en) * | 2011-06-15 | 2011-10-26 | 西安交通大学 | Sodium humate skin external preparation for promoting wound healing |
| CN102942588A (en) * | 2012-11-16 | 2013-02-27 | 深圳市沙特尔工业材料有限公司 | Preparation method of colorless phytic acid |
| CN103446290A (en) * | 2013-07-12 | 2013-12-18 | 六枝特区人民医院 | Burn tincture as well as preparation method and application thereof |
| CN103446290B (en) * | 2013-07-12 | 2015-04-22 | 六枝特区人民医院 | Burn tincture as well as preparation method and application thereof |
| CN103833787A (en) * | 2014-01-25 | 2014-06-04 | 深圳市沙特尔工业材料有限公司 | Preparation method for phytic acid |
Non-Patent Citations (3)
| Title |
|---|
| 何深义，伍明忠: ""腐植酸钠治疗烧烫伤116例临床观察与体会"", 《江西腐植酸》 * |
| 江西省瑞昌县人民医院外科: ""腐殖酸钠治疗烧伤"", 《新医药学杂志》 * |
| 王利萍等: ""腐植酸烧伤液外涂效果的观察与体会"", 《腐植酸》 * |
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Application publication date: 20170815 |