CN107029151A - 用于治疗心脾两虚型失眠的药物 - Google Patents
用于治疗心脾两虚型失眠的药物 Download PDFInfo
- Publication number
- CN107029151A CN107029151A CN201710307852.9A CN201710307852A CN107029151A CN 107029151 A CN107029151 A CN 107029151A CN 201710307852 A CN201710307852 A CN 201710307852A CN 107029151 A CN107029151 A CN 107029151A
- Authority
- CN
- China
- Prior art keywords
- parts
- root
- heart
- medicine
- deficiency
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 29
- 210000000952 spleen Anatomy 0.000 title claims abstract description 29
- 230000007812 deficiency Effects 0.000 title claims abstract description 28
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 title claims abstract description 25
- 206010022437 insomnia Diseases 0.000 title claims abstract description 25
- 229940079593 drug Drugs 0.000 title description 8
- 241001061906 Caragana Species 0.000 claims abstract description 11
- 241000732800 Cymbidium Species 0.000 claims abstract description 11
- 240000005979 Hordeum vulgare Species 0.000 claims abstract description 11
- 235000007340 Hordeum vulgare Nutrition 0.000 claims abstract description 11
- 240000000604 Lespedeza bicolor Species 0.000 claims abstract description 11
- 235000016677 Lespedeza bicolor Nutrition 0.000 claims abstract description 11
- 235000012629 Mentha aquatica Nutrition 0.000 claims abstract description 11
- 240000000275 Persicaria hydropiper Species 0.000 claims abstract description 11
- 235000017337 Persicaria hydropiper Nutrition 0.000 claims abstract description 11
- 235000004442 Polygonum persicaria Nutrition 0.000 claims abstract description 11
- 240000009038 Viola odorata Species 0.000 claims abstract description 11
- 235000013487 Viola odorata Nutrition 0.000 claims abstract description 11
- 235000019640 taste Nutrition 0.000 claims abstract description 11
- 241000207199 Citrus Species 0.000 claims abstract description 10
- 241001412225 Firmiana simplex Species 0.000 claims abstract description 10
- 229930184510 Mallotus Natural products 0.000 claims abstract description 10
- 241001060384 Mallotus <angiosperm> Species 0.000 claims abstract description 10
- 244000248021 Vitex negundo Species 0.000 claims abstract description 10
- 235000013427 Vitex negundo var incisa Nutrition 0.000 claims abstract description 10
- 235000014961 Vitex negundo var negundo Nutrition 0.000 claims abstract description 10
- 235000020971 citrus fruits Nutrition 0.000 claims abstract description 10
- 239000000463 material Substances 0.000 claims abstract description 10
- 235000014956 negundo chastetree Nutrition 0.000 claims abstract description 10
- 241001232328 Heterotheca Species 0.000 claims description 10
- 240000008564 Boehmeria nivea Species 0.000 claims description 3
- 239000008280 blood Substances 0.000 abstract description 27
- 210000004369 blood Anatomy 0.000 abstract description 27
- 230000000694 effects Effects 0.000 abstract description 6
- 231100000331 toxic Toxicity 0.000 abstract description 3
- 230000002588 toxic effect Effects 0.000 abstract description 3
- 241000990380 Heterotheca grandiflora Species 0.000 abstract 1
- 206010011224 Cough Diseases 0.000 description 11
- 210000004072 lung Anatomy 0.000 description 6
- 206010012735 Diarrhoea Diseases 0.000 description 5
- 230000007958 sleep Effects 0.000 description 5
- 206010000087 Abdominal pain upper Diseases 0.000 description 4
- 206010062717 Increased upper airway secretion Diseases 0.000 description 4
- 208000002193 Pain Diseases 0.000 description 4
- 235000009508 confectionery Nutrition 0.000 description 4
- 208000014674 injury Diseases 0.000 description 4
- 210000003734 kidney Anatomy 0.000 description 4
- 208000026435 phlegm Diseases 0.000 description 4
- 239000010902 straw Substances 0.000 description 4
- 230000008736 traumatic injury Effects 0.000 description 4
- 230000002618 waking effect Effects 0.000 description 4
- 201000005702 Pertussis Diseases 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 3
- 230000001939 inductive effect Effects 0.000 description 3
- 201000005630 leukorrhea Diseases 0.000 description 3
- 210000002784 stomach Anatomy 0.000 description 3
- 206010046901 vaginal discharge Diseases 0.000 description 3
- 206010007247 Carbuncle Diseases 0.000 description 2
- 208000032843 Hemorrhage Diseases 0.000 description 2
- 208000008454 Hyperhidrosis Diseases 0.000 description 2
- 208000004880 Polyuria Diseases 0.000 description 2
- 208000004078 Snake Bites Diseases 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 230000003213 activating effect Effects 0.000 description 2
- 230000001142 anti-diarrhea Effects 0.000 description 2
- 210000001367 artery Anatomy 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- 208000028659 discharge Diseases 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 201000006549 dyspepsia Diseases 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 230000023597 hemostasis Effects 0.000 description 2
- 235000021374 legumes Nutrition 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 230000036565 night sweats Effects 0.000 description 2
- 206010029410 night sweats Diseases 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 235000021251 pulses Nutrition 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 230000002269 spontaneous effect Effects 0.000 description 2
- 208000018556 stomach disease Diseases 0.000 description 2
- 210000002105 tongue Anatomy 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 210000001835 viscera Anatomy 0.000 description 2
- 206010000060 Abdominal distension Diseases 0.000 description 1
- 208000006820 Arthralgia Diseases 0.000 description 1
- 206010006458 Bronchitis chronic Diseases 0.000 description 1
- 206010007134 Candida infections Diseases 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 240000004528 Catalpa ovata Species 0.000 description 1
- 235000010005 Catalpa ovata Nutrition 0.000 description 1
- 206010007882 Cellulitis Diseases 0.000 description 1
- 206010008909 Chronic Hepatitis Diseases 0.000 description 1
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 description 1
- 244000192528 Chrysanthemum parthenium Species 0.000 description 1
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 description 1
- 235000005979 Citrus limon Nutrition 0.000 description 1
- 244000131522 Citrus pyriformis Species 0.000 description 1
- 244000080335 Citrus x limonia Species 0.000 description 1
- 235000001936 Citrus x limonia Nutrition 0.000 description 1
- 208000034656 Contusions Diseases 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 244000044554 Elaeagnus pungens Species 0.000 description 1
- 235000013935 Elaeagnus pungens Nutrition 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 208000008967 Enuresis Diseases 0.000 description 1
- 201000000297 Erysipelas Diseases 0.000 description 1
- 241000221079 Euphorbia <genus> Species 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 206010018612 Gonorrhoea Diseases 0.000 description 1
- 241000257303 Hymenoptera Species 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 208000004356 Hysteria Diseases 0.000 description 1
- 208000006877 Insect Bites and Stings Diseases 0.000 description 1
- 241001113320 Ligularia fischeri Species 0.000 description 1
- 206010054949 Metaplasia Diseases 0.000 description 1
- 206010027514 Metrorrhagia Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 208000007027 Oral Candidiasis Diseases 0.000 description 1
- 241000233855 Orchidaceae Species 0.000 description 1
- 206010033078 Otitis media Diseases 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 241000219050 Polygonaceae Species 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 206010038490 Renal pain Diseases 0.000 description 1
- 241001093501 Rutaceae Species 0.000 description 1
- 240000006079 Schisandra chinensis Species 0.000 description 1
- 235000008422 Schisandra chinensis Nutrition 0.000 description 1
- 241000758724 Schisandraceae Species 0.000 description 1
- 206010042170 Strangury Diseases 0.000 description 1
- 241000287411 Turdidae Species 0.000 description 1
- 206010046555 Urinary retention Diseases 0.000 description 1
- 206010046788 Uterine haemorrhage Diseases 0.000 description 1
- 241001073567 Verbenaceae Species 0.000 description 1
- 241001106476 Violaceae Species 0.000 description 1
- 244000029684 Vitex negundo var. negundo Species 0.000 description 1
- 208000019790 abdominal distention Diseases 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000001139 anti-pruritic effect Effects 0.000 description 1
- 239000003908 antipruritic agent Substances 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 206010006451 bronchitis Diseases 0.000 description 1
- 208000034526 bruise Diseases 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 201000003984 candidiasis Diseases 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 208000007451 chronic bronchitis Diseases 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 208000012839 conversion disease Diseases 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 208000013219 diaphoresis Diseases 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 230000005059 dormancy Effects 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000008451 emotion Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 235000008384 feverfew Nutrition 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 208000006750 hematuria Diseases 0.000 description 1
- 208000014617 hemorrhoid Diseases 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 208000013403 hyperactivity Diseases 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 230000004630 mental health Effects 0.000 description 1
- 230000015689 metaplastic ossification Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 201000009240 nasopharyngitis Diseases 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 230000032696 parturition Effects 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 230000005070 ripening Effects 0.000 description 1
- 210000000697 sensory organ Anatomy 0.000 description 1
- 238000007086 side reaction Methods 0.000 description 1
- 230000003860 sleep quality Effects 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
- 201000002327 urinary tract obstruction Diseases 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8998—Hordeum (barley)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/86—Violaceae (Violet family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开了一种用于治疗心脾两虚型失眠的药物，由下述重量配比的中药原料组成：苎麻根8‑15份，金雀根5‑10份，卷茎蓼10‑20份，胡枝子3‑10份，白背叶10‑20份，宜梧5‑10份，黄荆根10‑20份，建兰叶8‑12份，大麦秸10‑20份，山紫菀5‑15份，柠檬叶10‑20份，香堇菜5‑15份，舞草8‑10份，滇五味5‑15份。本发明的药物诸药配伍具有补益心脾、养血安神、镇静理气的功效，对心脾两虚型失眠疗效显著，治愈率高，安全无毒副作用。
Description
技术领域
本发明属于中药领域，具体涉及一种用于治疗心脾两虚型失眠的药物。
背景技术
失眠是指经常不能获得正常的睡眠而言，轻症者表现为入睡困难，或时寐时醒或醒后不寐，严重者可整夜不得入睡。近年来，随着人们生活节奏的加快、生存压力的增加，患病率呈不断上升趋势。失眠严重危害人们的身心健康，影响正常的工作、学习和生活。失眠患者每以情志变化，精神刺激为主要原因，失眠的主要病机是机体脏腑阴阳失调、气血失和，以致心神不宁。主要由七情所伤，思虑太过或突受惊吓引起，亦有禀赋不足，年迈体弱，气血、阴阴失衡，脏腑功能不调所致。临床上根据不同的临床现及与脏腑之不同，将失眠分为以下几型：心脾两虚型、阴虚火旺型、心肾不交型、肝郁化火型、心虚胆怯型、痰热内扰型、胃气不和型。
中医认为，心脾两虚型失眠主要是由于心脾两虚，营血不足，不能奉养心神，致使心神不安，而生失眠、多梦、醒后不易入睡；血虚不能上荣于面，所以面色少华而萎黄；心悸、心慌、神疲、乏力均为气血不足之象；脾气虚则饮食无味，脾不健运则食后腹胀，胃气虚弱则不思饮食，或饮食减少；舌淡、脉缓弱，均为气虚、血少之征。本型病人多为劳心过度，伤心耗血，或妇女崩漏日久，产后失血，病人体衰或行大手术后以及年老气虚血少等，引起气血不足，无以奉养心神而致不寐。有的病人则饮食劳倦伤及脾胃，胃气不和，脾阳不运，食少纳呆，气血化生来源不足，无以养心，而致心脾两虚。正如《景岳全书·不寐》中说：无邪而不寐者，必营血之不足，营主血，血虚则无以养心，心虚则神不守舍。
发明内容
本发明的目的在于提供一种治愈率高、安全无毒副作用的用于治疗心脾两虚型失眠的药物。
本发明解决其技术问题所采用的技术方案是：用于治疗心脾两虚型失眠的药物，由下述重量配比的中药原料组成：苎麻根8-15份，金雀根5-10份，卷茎蓼10-20份，胡枝子3-10份，白背叶10-20份，宜梧5-10份，黄荆根10-20份，建兰叶8-12份，大麦秸10-20份，山紫菀5-15份，柠檬叶10-20份，香堇菜5-15份，舞草8-10份，滇五味5-15份。
优选的，用于治疗心脾两虚型失眠的药物，由下述重量配比的中药原料组成：苎麻根10份，金雀根8份，卷茎蓼15份，胡枝子8份，白背叶15份，宜梧8份，黄荆根15份，建兰叶10份，大麦秸15份，山紫菀10份，柠檬叶15份，香堇菜10份，舞草8份，滇五味10份。
本发明各中药原料的药理活性如下：
苎麻根，为荨麻科植物苎麻的根，甘，寒，清热，止血，解毒，散瘀。治热病大渴、大狂，血淋，癃闭，吐血，下血，赤白带下，丹毒，痈肿，跌打损伤，蛇虫咬伤。
金雀根，为豆科植物锦鸡儿的根或根皮，苦辛，平，清肺益脾，活血通脉。治虚损劳热、咳嗽，高血压，妇女白带、血崩，关节痛风，跌打损伤。
卷茎蓼，为蓼科植物卷茎蓼的全草，辛，性温，健脾消食。主消化不良；腹泻。
胡枝子，为豆科植物胡枝子的枝叶，甘，平，归心、肝经，清热润肺；利尿通淋；止血。主肺热咳嗽；感冒发热；百日咳；淋证；吐血；衄血；尿血；便血。
白背叶，为大戟科植物白楸的叶，味苦，性平，归肝、脾经，清热；解毒；祛湿；止血。主蜂窝组织炎；化脓性中耳炎；鹅口疮；湿疹；跌打损伤；外伤出血。《南宁市药物志》："清热，利水，祛风湿，止痛。治淋浊，痔疮，跌打，蛇伤。止痒，消肿。"
宜梧，为胡颓子科植物福建胡颓子的根，苦，酸，微温，祛风活血；健脾益肾。主风湿痹痛；跌打瘀肿；慢性肝炎；胃痛腹泻；消化不良；肾亏腰痛；劳倦乏力；盗汗。
黄荆根，为马鞭草科植物黄荆的根，味辛，微苦，性温，归心经，解表；止咳；祛风除湿；理气止痛。主感冒；慢性气管炎；风湿痹痛；胃痛；痧气；腹痛。
建兰叶，为兰科植物建兰的叶片，味辛，平，清热，凉血，理气，利湿。治咳嗽，肺痈，吐血，咯血，白浊，白带，疮毒，疔肿。
大麦秸，为禾本科植物大麦成熟后枯黄的茎秆，甘苦，温，归脾、肺经，利湿消肿；理气。主小便不通；心胃气痛。
山紫菀，为菊科植物蹄叶橐吾的根及根茎，味辛，性微温，祛痰；止咳；理气活血；止痛。主咳嗽；普多气喘；百日咳；腰腿痛；劳伤；跌打损伤。
柠檬叶，为芸香科植物黎檬或洋柠檬的叶，辛，甘，微苦，微温，归肺、胃、大肠经，治化痰止咳；理气和胃；止泻。主咳喘痰多；气滞腹胀；泄泻。
香堇菜，为堇菜科植物香堇菜的全草，味辛，微苦，性凉，疏风清热；止咳祛痰；镇静；止泻。主伤风咳嗽；百日咳；癔病；失眠；腹泻；痢疾。
舞草，为豆科舞草的全草，微涩，平，安神，镇静，祛瘀生新，活血消肿。
滇五味，为五味子科植物红花五味子的成熟果实，酸，甘，性温，归肺、心、肾经，收敛固涩；益气生津；补肾宁心。主久嗽虚喘；梦遗滑精；遗尿尿频；久泻不止；自汗；盗汗；津伤口渴；短气脉虚；内热消渴；心悸失眠。
本发明具有以下有益效果：本发明的药物诸药配伍具有补益心脾、养血安神、镇静理气的功效，对心脾两虚型失眠疗效显著，治愈率高，安全无毒副作用。
具体实施方式
以下是本发明的具体实施例，对本发明的技术方案做进一步描述，但是本发明的保护范围并不限于这些实施例。凡是不背离本发明构思的改变或等同替代均包括在本发明的保护范围之内。
实施例1
用于治疗心脾两虚型失眠的药物，由下述重量配比的中药原料组成：苎麻根10份，金雀根8份，卷茎蓼15份，胡枝子8份，白背叶15份，宜梧8份，黄荆根15份，建兰叶10份，大麦秸15份，山紫菀10份，柠檬叶15份，香堇菜10份，舞草8份，滇五味10份。
实施例2
用于治疗心脾两虚型失眠的药物，由下述重量配比的中药原料组成：苎麻根8份，金雀根5份，卷茎蓼18份，胡枝子10份，白背叶10份，宜梧7份，黄荆根20份，建兰叶9份，大麦秸10份，山紫菀7份，柠檬叶20份，香堇菜5份，舞草9份，滇五味15份。
实施例3
用于治疗心脾两虚型失眠的药物，由下述重量配比的中药原料组成：苎麻根15份，金雀根7份，卷茎蓼10份，胡枝子5份，白背叶20份，宜梧5份，黄荆根10份，建兰叶12份，大麦秸20份，山紫菀5份，柠檬叶18份，香堇菜15份，舞草10份，滇五味5份。
实施例4
用于治疗心脾两虚型失眠的药物，由下述重量配比的中药原料组成：苎麻根13份，金雀根10份，卷茎蓼20份，胡枝子3份，白背叶13份，宜梧10份，黄荆根13份，建兰叶8份，大麦秸13份，山紫菀15份，柠檬叶10份，香堇菜13份，舞草9份，滇五味12份。
临床资料
对150例确诊为心脾两虚型失眠的患者进行治疗，其中男性70例，女性80例，年龄19-71岁。
治疗方法：本发明药物按常规方法水煎服，每日一剂，一日两次，早晚分服，七天为一个疗程。
疗效判断标准：
痊愈：睡眠时间恢复正常或睡觉时间6小时以上，睡眠深，醒后精力充沛；
有效：睡眠好转，睡觉时间3小时以上；
无效：治疗后睡眠时间无改善。
治疗结果：经1-3个疗程的治疗，150例患者治愈125例，有效19例，无效6例，治愈率83.3％，总有效率96％，治疗过程中患者未出现不良副反应。
典型病例
吴某某，女，50岁，长期不易入睡，心神不安，健忘乏力，舌淡，脉缓弱，经检查诊断为心脾两虚型失眠，用本发明药物治疗一个疗程后症状即减轻，继续治疗一个疗程诸症悉除，睡眠质量良好，痊愈。
Claims (2)
1.用于治疗心脾两虚型失眠的药物，其特征在于，由下述重量配比的中药原料组成：苎麻根8-15份，金雀根5-10份，卷茎蓼10-20份，胡枝子3-10份，白背叶10-20份，宜梧5-10份，黄荆根10-20份，建兰叶8-12份，大麦秸10-20份，山紫菀5-15份，柠檬叶10-20份，香堇菜5-15份，舞草8-10份，滇五味5-15份。
2.如权利要求1所述的用于治疗心脾两虚型失眠的药物，其特征在于，由下述重量配比的中药原料组成：苎麻根10份，金雀根8份，卷茎蓼15份，胡枝子8份，白背叶15份，宜梧8份，黄荆根15份，建兰叶10份，大麦秸15份，山紫菀10份，柠檬叶15份，香堇菜10份，舞草8份，滇五味10份。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710307852.9A CN107029151A (zh) | 2017-05-04 | 2017-05-04 | 用于治疗心脾两虚型失眠的药物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710307852.9A CN107029151A (zh) | 2017-05-04 | 2017-05-04 | 用于治疗心脾两虚型失眠的药物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107029151A true CN107029151A (zh) | 2017-08-11 |
Family
ID=59537657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710307852.9A Pending CN107029151A (zh) | 2017-05-04 | 2017-05-04 | 用于治疗心脾两虚型失眠的药物 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107029151A (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3485894A1 (en) * | 2017-11-20 | 2019-05-22 | Italfarmaco SpA | Combination of officinal plants and their use in the treatment and/or prevention of sleep disorders |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103816332A (zh) * | 2013-12-10 | 2014-05-28 | 济南新起点医药科技有限公司 | 一种治疗由心脾两虚引起失眠的中药组合物 |
-
2017
- 2017-05-04 CN CN201710307852.9A patent/CN107029151A/zh active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103816332A (zh) * | 2013-12-10 | 2014-05-28 | 济南新起点医药科技有限公司 | 一种治疗由心脾两虚引起失眠的中药组合物 |
Non-Patent Citations (2)
| Title |
|---|
| 国家中医药管理局中华本草编委会: "《中华本草》", 30 September 1999, 上海科学技术出版社 * |
| 许翊坂: "归脾汤加减治疗心脾两虚型失眠的疗效观察", 《中国社区医师(医学专业)》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3485894A1 (en) * | 2017-11-20 | 2019-05-22 | Italfarmaco SpA | Combination of officinal plants and their use in the treatment and/or prevention of sleep disorders |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104146261B (zh) | 一种妇女更年期的中药保健品及其制备方法 | |
| CN103740565B (zh) | 抗疲劳调心情的美容养生酒及其制备方法 | |
| CN105597071A (zh) | 用于治疗仔猪缺铁性贫血的中药组合物及其制备方法 | |
| CN103638250B (zh) | 一种治疗面神经麻痹的中药制剂及其制备方法 | |
| CN1330352C (zh) | 一种保健酒及制备方法 | |
| CN103893670B (zh) | 一种治疗心脑血管病的中药药丸 | |
| CN104522213A (zh) | 适宜三高人群饮用的茶饮及其制备方法 | |
| CN104605387A (zh) | 减轻肿瘤患者术后放疗反应的营养药膳及制备方法 | |
| CN104605372A (zh) | 一种基于恶性肿瘤放疗患者的营养药膳及制备方法 | |
| CN109528966A (zh) | 一种保健酒及其制作方法 | |
| CN107029151A (zh) | 用于治疗心脾两虚型失眠的药物 | |
| CN114081912A (zh) | 一种具有通便功能的食用膏剂 | |
| CN112076305A (zh) | 一种治疗人体代谢症候群及杀菌消炎的中药制内服外用原液合剂 | |
| CN109674974A (zh) | 一种补肾固精养元膏药及其制备方法 | |
| CN104689240A (zh) | 一种治疗气滞血瘀型黄褐斑的药物及其制备方法 | |
| CN104687137A (zh) | 一种鹿茸健脑安神汤料的配方及生产方法 | |
| CN103961578A (zh) | 一种治疗神经衰弱的中药药酒 | |
| CN103263628A (zh) | 一种治疗糖尿病的中药 | |
| CN107137689A (zh) | 一种治疗更年期综合征的中药组合物 | |
| CN108272918A (zh) | 一种治疗胃癌的中药擦剂及其制备方法 | |
| CN106177415A (zh) | 一种治疗失眠症的中西药组合物及制备方法 | |
| CN106177659A (zh) | 活力草本液 | |
| CN103933368B (zh) | 用于治疗产后便秘的药物组合物及其制备方法 | |
| CN104922542A (zh) | 一种治疗脾肺气虚型小儿遗尿的药物及其制备方法 | |
| CN104510874A (zh) | 治疗产后大便郁结的中药颗粒及其制备方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170811 |
|
| RJ01 | Rejection of invention patent application after publication |