CN107020059A - One kind prepares 8 oxyquinolines and neutralizes kettle - Google Patents
One kind prepares 8 oxyquinolines and neutralizes kettle Download PDFInfo
- Publication number
- CN107020059A CN107020059A CN201710315149.2A CN201710315149A CN107020059A CN 107020059 A CN107020059 A CN 107020059A CN 201710315149 A CN201710315149 A CN 201710315149A CN 107020059 A CN107020059 A CN 107020059A
- Authority
- CN
- China
- Prior art keywords
- kettle
- value
- caustic soda
- liquid caustic
- upper cover
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims abstract description 90
- 239000007788 liquid Substances 0.000 claims abstract description 37
- 235000011121 sodium hydroxide Nutrition 0.000 claims abstract description 30
- 238000001514 detection method Methods 0.000 claims abstract description 19
- 230000008676 import Effects 0.000 claims abstract description 19
- 239000005725 8-Hydroxyquinoline Substances 0.000 claims description 15
- 229960003540 oxyquinoline Drugs 0.000 claims description 15
- MCJGNVYPOGVAJF-UHFFFAOYSA-N quinolin-8-ol Chemical compound C1=CN=C2C(O)=CC=CC2=C1 MCJGNVYPOGVAJF-UHFFFAOYSA-N 0.000 claims description 15
- 239000000523 sample Substances 0.000 claims description 6
- 239000000498 cooling water Substances 0.000 claims description 5
- 238000007599 discharging Methods 0.000 claims description 4
- 210000003298 dental enamel Anatomy 0.000 claims description 3
- 238000006386 neutralization reaction Methods 0.000 abstract description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 239000003513 alkali Substances 0.000 description 3
- 239000002826 coolant Substances 0.000 description 3
- CDAWCLOXVUBKRW-UHFFFAOYSA-N 2-aminophenol Chemical compound NC1=CC=CC=C1O CDAWCLOXVUBKRW-UHFFFAOYSA-N 0.000 description 2
- IQUPABOKLQSFBK-UHFFFAOYSA-N 2-nitrophenol Chemical compound OC1=CC=CC=C1[N+]([O-])=O IQUPABOKLQSFBK-UHFFFAOYSA-N 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N sulfuric acid Substances OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 239000002253 acid Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000012043 crude product Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 230000003472 neutralizing effect Effects 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0006—Controlling or regulating processes
- B01J19/002—Avoiding undesirable reactions or side-effects, e.g. avoiding explosions, or improving the yield by suppressing side-reactions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0086—Processes carried out with a view to control or to change the pH-value; Applications of buffer salts; Neutralisation reactions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/18—Stationary reactors having moving elements inside
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J4/00—Feed or outlet devices; Feed or outlet control devices
- B01J4/008—Feed or outlet control devices
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00049—Controlling or regulating processes
- B01J2219/00245—Avoiding undesirable reactions or side-effects
- B01J2219/00259—Preventing runaway of the chemical reaction
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
Abstract
One kind prepares 8 oxyquinolines and neutralized provided with upper cover at the top of kettle, including kettle, chuck and electric device, the kettle, and autoclave body bottom is provided with low head；Upper cover is provided with pH value detection mouth and liquid caustic soda import；PH value detection mouth is provided with PH value detector, and liquid caustic soda import is provided with feed tube, and feed tube is provided with flow detector and proportioning valve, and this neutralizations kettle can detect pH value in real time and have pH value warning function, regulation liquid caustic soda flow velocity that can be simple and convenient.
Description
Technical field
Prepare 8-hydroxyquinoline the present invention relates to 8-hydroxyquinoline preparation field, more particularly to one kind and neutralize kettle.
Background technology
8-hydroxyquinoline is after the quantitative concentrated sulfuric acid is slowly added into glycerine quantitative in synthesis reactor at normal temperatures,
O-aminophenol, o-nitrophenol, water are separately added under normal temperature, 130 DEG C or so are to slowly warm up to, continues to be slowly added to quantitative
The concentrated sulfuric acid, and be incubated.After end, add water, unnecessary o-nitrophenol is steamed.After cooling, viscous liquid is pumped into and neutralized
Kettle is neutralized to neutrality with liquid caustic soda, centrifugation.Crude product steams through rectifying still essence, cut into slices, packaging, obtains finished product 8-hydroxyquinoline.
8-hydroxyquinoline is practically insoluble in water and ether, but 8-hydroxyquinoline had not only been dissolved in acid but also had been dissolved in alkali and generates salt, into salt
After can not be taken out of by water vapour, therefore must note adjusting pH value when neutralizing, it is most of at present to neutralize in kettles using manually detecting
Mode, is detected with PH test paper to pH value, while the increase of liquid caustic soda can not be too fast, otherwise can also cause slug, at present big portion
Divide in neutralization kettle and the speed of liquid feeding is controlled using the mode of artificial plus alkali lye.
The content of the invention
PH value can be detected in real time and with pH value warning function, can adjust liquid caustic soda it is an object of the invention to provide one kind
One kind of flow velocity prepares 8-hydroxyquinoline and neutralizes kettle.
The technical solution adopted by the present invention is：One kind prepares 8-hydroxyquinoline and neutralizes kettle, including kettle, chuck and electronic
Upper cover is provided with the top of device, the kettle, autoclave body bottom is provided with low head；The chuck wraps kettle and low head, institute
Chuck side wall upper part is stated provided with coolant outlet, chuck bottom is provided with cooling water inlet；The low head bottom is provided with discharging opening；
Upper cover and the low head center connects rotary shaft, and rotary shaft is provided with agitating device, and the electric device is located at upper
At the top of end socket, it is connected with rotary shaft；The upper cover is provided with manhole, inlet, pH value detection mouth and liquid caustic soda import；The PH
It is worth detection mouth and is provided with PH value detector, the detection probe of the PH value detector stretches into autoclave body bottom；The liquid caustic soda import is stretched
Enter in upper cover, liquid caustic soda import is provided with feed tube, feed tube is provided with flow detector and proportioning valve, the connection of feed tube top
Liquid reserve tank, the PH value detector connects pH value alarm.Preferably, visor is additionally provided with the upper cover, the visor
It is directed at liquid caustic soda import.
Preferably, being sealed between the liquid caustic soda import and feed tube with elastic tape.
Preferably, being sealed between the pH value detection mouth and PH value detector with elastic tape.
Preferably, the kettle, upper cover and low head are enamel.
Beneficial effects of the present invention：PH value detector is connected by pH value detection mouth, PH value detector probe stretches into kettle
Bottom, PH value detector connection pH value alarm, the pH value of solution can be detected in real time, once pH value exceedes setting value, pH value
Alarm sends alarm；Liquid caustic soda import connects Set scale valve and flow detector on feed tube, feed tube, can be convenient and swift
Control liquid caustic soda flow velocity, by visor can also Real Time Observation liquid caustic soda flow condition and chemical reaction situation.
Brief description of the drawings
Fig. 1 is schematic structural view of the invention.
In figure：1 it is kettle, 2 be chuck, 3 be electric device, 4 be upper cover, 5 be low head, 6 be rotary shaft, 7 is to stir
Mix device, 8 coolant outlets, 9 be cooling water inlet, 10 be discharging opening, 11 be inlet, 12 be pH value detection mouth, 13 be liquid
Alkali import, 14 be PH value detector, 14.1 be detection probe, 15 be pH value alarm, 16 be liquid reserve tank, 17 be flow detection
Instrument, 18 be proportioning valve, 19 feed tubes, 20 be visor.
Specific embodiment
One kind prepares 8-hydroxyquinoline and neutralizes kettle, including kettle 1, chuck 2 and electric device 3, and the top of kettle 1 is set
There is upper cover 4, the bottom of kettle 1 is provided with low head 5；The chuck 2 is wrapped on kettle 1 and low head 5, the side wall of chuck 2
Portion is provided with coolant outlet 8, and the bottom of chuck 2 is provided with cooling water inlet 9；The bottom of low head 5 is provided with discharging opening 10；On described
End socket 4 and the center of low head 5 connection rotary shaft 6, rotary shaft 6 are provided with agitating device 7, and the electric device 3 is located at upper
The top of end socket 4, is connected with rotary shaft 6；The upper cover 4 is provided with manhole, inlet 11, pH value detection mouth 12 and liquid caustic soda import
13；The pH value detection mouth 12 is provided with PH value detector 14, and the detection probe 14.1 of the PH value detector 14 stretches into kettle 1
Bottom；The liquid caustic soda import 13 is stretched into upper cover 4, and liquid caustic soda import 13 is provided with feed tube 19, and feed tube 19 is provided with flow
Detector 17 and proportioning valve 18, the top of feed tube 19 connection liquid reserve tank 16, the connection pH value of PH value detector 14 alarm 15；
Visor 20, the alignment liquid caustic soda of visor 20 import 13 are additionally provided with the upper cover 4；The liquid caustic soda import 13 and feed tube 19 it
Between sealed with elastic tape；Sealed between the pH value detection mouth 12 and PH value detector 14 with elastic tape；The kettle 1, upper envelope
First 4 and low head 5 be enamel.
When adding liquid caustic soda, liquid caustic soda flows into feed tube 19 from liquid reserve tank 16, and feed tube 19 is provided with flow detector 17 and ratio
Example valve 18, proportioning valve 18 adjusts the flow velocity of liquid caustic soda, and operating personnel can observe liquid caustic soda flow velocity by visor 20, can also pass through flow
Detector 17 observes liquid caustic soda flow velocity, while liquid caustic soda is added, and the detection probe 14.1 of PH detectors 14 detects solution in real time
PH value, once pH value exceedes setting value, pH value alarm 15 sends alarm.
Claims (5)
1. one kind prepares 8-hydroxyquinoline and neutralized at the top of kettle, including kettle, chuck and electric device, the kettle provided with upper envelope
Head, autoclave body bottom is provided with low head；The chuck wraps kettle and low head, and the chuck side wall upper part goes out provided with cooling water
Mouthful, chuck bottom is provided with cooling water inlet；The low head bottom is provided with discharging opening；Upper cover and the low head center
Rotary shaft is connected, rotary shaft is provided with agitating device, and the electric device is located at the top of upper cover, is connected with rotary shaft；It is special
Levy and be：The upper cover is provided with manhole, inlet, pH value detection mouth and liquid caustic soda import；The pH value detection mouth is provided with
PH value detector, the detection probe of the PH value detector stretches into autoclave body bottom；The liquid caustic soda import is stretched into upper cover, liquid caustic soda
Import is provided with feed tube, and feed tube is provided with flow detector and proportioning valve, feed tube top connection liquid reserve tank, the pH value
Detector connects pH value alarm.
2. one kind according to claim 1 prepares 8-hydroxyquinoline and neutralizes kettle, it is characterised in that：On the upper cover also
Provided with visor, the visor is directed at liquid caustic soda import.
3. one kind according to claim 1 prepares 8-hydroxyquinoline and neutralizes kettle, it is characterised in that：The liquid caustic soda import and
Sealed between feed tube with elastic tape.
4. one kind according to claim 1 prepares 8-hydroxyquinoline and neutralizes kettle, it is characterised in that：The pH value detection mouth
Sealed between PH value detector with elastic tape.
5. one kind according to claim 1 prepares 8-hydroxyquinoline and neutralizes kettle, it is characterised in that：The kettle, upper envelope
Head and low head are enamel.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710315149.2A CN107020059A (en) | 2017-05-08 | 2017-05-08 | One kind prepares 8 oxyquinolines and neutralizes kettle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710315149.2A CN107020059A (en) | 2017-05-08 | 2017-05-08 | One kind prepares 8 oxyquinolines and neutralizes kettle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107020059A true CN107020059A (en) | 2017-08-08 |
Family
ID=59530265
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710315149.2A Pending CN107020059A (en) | 2017-05-08 | 2017-05-08 | One kind prepares 8 oxyquinolines and neutralizes kettle |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107020059A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115057793A (en) * | 2022-07-28 | 2022-09-16 | 湖州欧利生物科技有限公司 | Production process of N-fatty acyl disodium glutamate |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105183026A (en) * | 2015-08-26 | 2015-12-23 | 宁波金和锂电材料有限公司 | Automatic adjustment system for adjusting pH value of crystallization reaction |
| CN204933459U (en) * | 2015-08-17 | 2016-01-06 | 浙江衢州鼎盛建材有限公司 | A kind of water reducer is produced in use and still |
| CN105541576A (en) * | 2015-12-22 | 2016-05-04 | 安徽金禾实业股份有限公司 | DCS control system used for amination workshop section in methyl cyclopentenolone production line |
| CN205659681U (en) * | 2016-06-08 | 2016-10-26 | 成都大蓉新材料有限责任公司 | A apparatus for producing for resin is synthetic |
| CN205933700U (en) * | 2016-08-29 | 2017-02-08 | 石家庄杰克化工有限公司 | EDTA 2Na continuous production system |
| CN206731120U (en) * | 2017-05-08 | 2017-12-12 | 宜兴市宏博精细化工有限公司 | One kind prepares 8 oxyquinolines and neutralizes kettle |
-
2017
- 2017-05-08 CN CN201710315149.2A patent/CN107020059A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN204933459U (en) * | 2015-08-17 | 2016-01-06 | 浙江衢州鼎盛建材有限公司 | A kind of water reducer is produced in use and still |
| CN105183026A (en) * | 2015-08-26 | 2015-12-23 | 宁波金和锂电材料有限公司 | Automatic adjustment system for adjusting pH value of crystallization reaction |
| CN105541576A (en) * | 2015-12-22 | 2016-05-04 | 安徽金禾实业股份有限公司 | DCS control system used for amination workshop section in methyl cyclopentenolone production line |
| CN205659681U (en) * | 2016-06-08 | 2016-10-26 | 成都大蓉新材料有限责任公司 | A apparatus for producing for resin is synthetic |
| CN205933700U (en) * | 2016-08-29 | 2017-02-08 | 石家庄杰克化工有限公司 | EDTA 2Na continuous production system |
| CN206731120U (en) * | 2017-05-08 | 2017-12-12 | 宜兴市宏博精细化工有限公司 | One kind prepares 8 oxyquinolines and neutralizes kettle |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115057793A (en) * | 2022-07-28 | 2022-09-16 | 湖州欧利生物科技有限公司 | Production process of N-fatty acyl disodium glutamate |
| CN115057793B (en) * | 2022-07-28 | 2024-04-16 | 湖州欧利生物科技有限公司 | Production process of N-fatty acyl disodium glutamate |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170808 |