CN107007743A - For treating the qi-blood deficiency leukemogenic compound Chinese medicinal preparation of institute and preparation method - Google Patents
For treating the qi-blood deficiency leukemogenic compound Chinese medicinal preparation of institute and preparation method Download PDFInfo
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Abstract
One kind is used to treat qi-blood deficiency institute leukemogenic compound Chinese medicinal preparation and preparation method.Preparation by consumption by weight than agents raw material be made：Ginseng 6-15, astragalus root 18-48, ganoderma lucidum 6-15, rhizoma atractylodis macrocephalae 9-24, Poria cocos 9-24, sealwort 6-15, radix polygonati officinalis 6-15, prepared rhizome of rehmannia 18-48, Radix Angelicae Sinensis 6-15, donkey-hide gelatin 6-15, hairyvein agrimony 18-48, Sculellaria barbata 18-48, oldenlandia diffusa 18-48, honey-fried licorice root 4-10.Invention formulation is to boil the method for extraction using water to extract active ingredient in material medicine, and keeps its activity, so not only can greatly improve the dissolution rate of active ingredient in medicine, and contributes to the absorption of medicine, so as to improve its bioavilability.In addition, medicine is pure Chinese medicine compound preparation, thus toxic side effect will not be produced after patient's long-term taking, so security is good.In addition, the preparation method technique of the present invention is simple, it is easy to operate.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof, more particularly to a kind of use being made using Chinese medicine as raw material
In the qi-blood deficiency leukemogenic compound Chinese medicinal preparation of institute for the treatment of and preparation method.
Background technology
Leukaemia is also known as leukemia, is due to caused by healthy tendency internal weakness, the malicious heresy of warm are taken advantage of a weak point, turbid with heat toxin, blood stasis, phlegm
Mutually tie, human body blood trouble is basic pathogenesis, with heating, bleeding, anaemia and liver, spleen, enlargement of lymph nodes etc. for main clinical manifestation
A kind of malignant tumour of hemopoietic system.Although the types of drugs for being clinically used to treat leukaemia at present is a lot, specific aim is not
By force, and some drugs toxic side effect it is big, so after taking for treatment belong to it is qi-blood deficiency caused by this disease of leukaemia
DeGrain for disease.
The content of the invention
It is leukemogenic for treating qi-blood deficiency institute it is an object of the invention to provide one kind in order to solve the above problems
Compound Chinese medicinal preparation and preparation method.
In order to achieve the above object, provided by the present invention for treating the leukemogenic compound Chinese medicinal preparation of qi-blood deficiency institute
By consumption by weight than agents raw material be made：
The described preparation method for being used to treating qi-blood deficiency leukemogenic compound Chinese medicinal preparation is according to following step
Rapid order is carried out：
(a) the other medicines raw material in said medicine raw material in addition to ginseng and donkey-hide gelatin is weighed and mixed according to proportioning
Close, then soak 25 minutes, decoct 30 minutes afterwards, filter and remove residue；
(b) donkey-hide gelatin is ground into fritter or powder, adds a little yellow rice wine, water proof heating is steamed to dissolving；
(c) ginseng is cut into slices or smashed as fritter, soak 25 minutes, decoct 40 minutes afterwards, filter and remove residue；
(d) by step (a), obtained by step (c) clear liquid be well mixed with step (b) gained donkey-hide gelatin solution can be made into it is described
Be used for treat the leukemogenic compound Chinese medicinal preparation of qi-blood deficiency institute.
Described compound Chinese medicinal preparation can be made with conventional pharmaceutic adjuvant granule, tablet, capsule, syrup,
Oral liquid, pill and paste.
Extraction is boiled provided by the present invention for treating qi-blood deficiency leukemogenic compound Chinese medicinal preparation using water
Method extracts the active ingredient in material medicine, and keeps its activity, so can not only make the dissolution of active ingredient in medicine
Degree is greatly improved, and contributes to the absorption of medicine, so as to improve its bioavilability.In addition, the medicine of the present invention is
Pure Chinese medicine compound preparation, thus toxic side effect will not be produced after patient's long-term taking, so security is good.In addition, the present invention
Preparation method technique is simple, easy to operate.
Embodiment
Leukaemia complicated symptoms, course of disease delay, complication is more.Clinical common asthenic symptoms, real example and syndrome of intermingled deficiency and excess etc..This
Fang Lifa is qi-blood tonifying in nourishing qi and blood.Ginseng sweet slight bitter is put down in side, is reinforced vital energy, and tonifying lung benefit spleen, is monarch drug in a prescription.Astragalus root is sweet
Tepor, replenishes qi to invigorate the spleen, and is the key medicine of tonifying middle-Jiao and Qi；Rhizoma atractylodis macrocephalae sweetness and bitterness temperature, replenishes qi to invigorate the spleen, eliminating dampness diuresis, is air making-up and spleen enlivening first
Key medicine；Sealwort is sweet flat, boosting qi and nourishing yin, invigorating the spleen moistening lung, kidney-nourishing；The sweet tepor of prepared rhizome of rehmannia, yin-nourishing of enriching blood, life essence-filling, marrow-benefitting；Donkey-hide gelatin is sweet flat,
Tonify the blood and arrest bleeding, nourishing Yin and moistening lung, for the key medicine enriched blood；Sculellaria barbata is pungent cool, clearing heat and detoxicating, and diuresis, swelling and pain relieving, anticancer, the above is all
Medicine, air making-up and spleen enlivening, nourishing yin and supplementing blood, swelling and pain relieving is altogether ministerial drug.Ganoderma lucidum is sweet flat, invigorating qi for tranquilization；Poria cocos is sweet light flat, clearing damp and promoting diuresis,
Strengthening the spleen and reducing phlegm, antitoxic heart-soothing and sedative；Radix polygonati officinalis is sweet to be slightly cold, and nourishing Yin and moistening lung is promoted the production of body fluid；Radix Angelicae Sinensis Gan Xinwen, enriches blood, promoting blood circulation and stopping pain；Hairyvein agrimony is bitter
It is puckery flat, astringing to arrest bleeding, qi-restoratives；Oldenlandia diffusa slight bitter is sweet cold, and clearing heat and detoxicating, dampness removing is treating stranguria, and all medicines of the above, invigorating spleen for diuresis disappears
Swollen analgesic, is adjutant.Honey-fried licorice root is sweet flat, invigorates the spleen and benefits qi, clearing heat and detoxicating analgesic, coordinating the drug actions of a prescription, and thinking makes medicine.Our qi and blood is double
Mend, while there is detumescence, analgesic, the work(of anticancer, therefore suitable for qi-blood deficiency caused leukaemia.
With reference to embodiment to provided by the present invention for treating the leukemogenic compound Chinese medicinal preparation of qi-blood deficiency institute
And preparation method is described in detail.
Embodiment 1：
It is weight ratio that what the present embodiment was provided, which is used to treat the leukemogenic compound Chinese medicinal preparation of qi-blood deficiency institute by consumption,
Agents raw material be made：
Preparation method is carried out according to the following steps order：
(a) the other medicines raw material in said medicine raw material in addition to ginseng and donkey-hide gelatin is weighed and mixed according to proportioning
Close, then soak 25 minutes, decoct 30 minutes afterwards, filter and remove residue；
(b) donkey-hide gelatin is ground into fritter or powder, adds a little yellow rice wine, water proof heating is steamed to dissolving；
(c) ginseng is cut into slices or smashed as fritter, soak 25 minutes, decoct 40 minutes afterwards, filter and remove residue；
(d) by step (a), obtained by step (c) clear liquid be well mixed with step (b) gained donkey-hide gelatin solution can be made into it is described
Be used for treat the leukemogenic compound Chinese medicinal preparation of qi-blood deficiency institute.
In addition, granule, tablet, capsule, sugar can be made with conventional pharmaceutic adjuvant in described compound Chinese medicinal preparation
Starch agent, oral liquid, pill and paste.
Embodiment 2：
It is weight ratio that what the present embodiment was provided, which is used to treat the leukemogenic compound Chinese medicinal preparation of qi-blood deficiency institute by consumption,
Agents raw material be made：
Preparation method be the same as Example 1.
Embodiment 3：
It is weight ratio that what the present embodiment was provided, which is used to treat the leukemogenic compound Chinese medicinal preparation of qi-blood deficiency institute by consumption,
Agents raw material be made：
Preparation method be the same as Example 1.
Provided by the present invention for treating the leukemogenic compound Chinese medicinal preparation of qi-blood deficiency institute in brown to sepia；Gas
It is light, mildly bitter flavor.In order to verify the therapeutic effect of the compound Chinese medicinal preparation, the present inventor is using above-mentioned compound Chinese medicinal preparation to 305
Patient of the example with QIXUELIANGXU type leukaemia has carried out system clinical observation, wherein 21-30 Sui patient 87,31-40 Sui 115
Example, 41-50 Sui 103, each medication 150ml, 3 times a day, is within 120 days 1 course for the treatment of.Cure (blood altogether after 1 course of therapy
Routine inspection is normal, and bone marrow smear checks normal, and chromosome examination is normal, and cardinal symptom is obviously improved) 7, account for 2.3%；Effectively
(every laboratory examination is obviously improved, and cardinal symptom has improvement) 136, accounts for 44.6%；Invalid (every laboratory examination is unchanged,
Cardinal symptom is without improving) 162, account for 53.1%；Total effective rate is 46.9%.12 are cured altogether after 2 course of therapy, are accounted for
3.9%；Effective 206, account for 67.5%；Invalid 87, account for 28.5%；Total effective rate is 71.5%.
Meanwhile, the present inventor is analyzed the relation between therapeutic effect and age, therapeutic effect and the course for the treatment of, analysis
As a result 1, table 2 is shown in Table respectively.
Table 1：The compound Chinese medicinal preparation therapeutic effect that the present invention is provided and age correlations table
By the data x in above-mentioned table 12Method of inspection is calculated, and is as a result 0.050 ＞ P ＞ 0.025, it is possible thereby to demonstrate,prove
It is bright to take the compound Chinese medicinal preparation that provides of the present invention to treat QIXUELIANGXU type leukaemia, to the therapeutic effect of each age group not with
Age and change.
Table 2：The compound Chinese medicinal preparation therapeutic effect that the present invention is provided and course for the treatment of relation table
By the data x in above-mentioned table 22Method of inspection is calculated, and is as a result P ＜ 0.005, it is possible thereby to prove to take this
Invent the compound Chinese medicinal preparation of offer to treat QIXUELIANGXU type leukaemia, with going deep into for treatment, cure rate, effective percentage are bright
It is aobvious to improve.
Claims (3)
1. one kind is used to treat the leukemogenic compound Chinese medicinal preparation of qi-blood deficiency institute, it is characterised in that：Described Chinese medicine compound prescription
Preparation by consumption by weight than agents raw material be made：
2. as claimed in claim 1 it is used to treating the preparation side of qi-blood deficiency leukemogenic compound Chinese medicinal preparation a kind of
Method, it is characterised in that：Described preparation method is carried out according to the following steps order：
(a) the other medicines raw material in said medicine raw material in addition to ginseng and donkey-hide gelatin is weighed and mixed according to proportioning,
Then soak 25 minutes, decoct 30 minutes afterwards, filter and remove residue；
(b) donkey-hide gelatin is ground into fritter or powder, adds a little yellow rice wine, water proof heating is steamed to dissolving；
(c) ginseng is cut into slices or smashed as fritter, soak 25 minutes, decoct 40 minutes afterwards, filter and remove residue；
(d) clear liquid obtained by step (a), step (c) is well mixed with donkey-hide gelatin solution obtained by step (b) and can be made into described use
In the qi-blood deficiency leukemogenic compound Chinese medicinal preparation of institute for the treatment of.
3. preparation method according to claim 2, it is characterised in that：Described compound Chinese medicinal preparation can be with conventional medicine
Granule, tablet, capsule, syrup, oral liquid, pill and paste are made of auxiliary material.
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101181516A (en) * | 2007-11-15 | 2008-05-21 | 王玉鑫 | Chinese medicine prescription orally taken for curing leukaemia |
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2017
- 2017-03-31 CN CN201710206805.5A patent/CN107007743A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101181516A (en) * | 2007-11-15 | 2008-05-21 | 王玉鑫 | Chinese medicine prescription orally taken for curing leukaemia |
Non-Patent Citations (1)
| Title |
|---|
| 屠佑堂: "《中医实用诊疗大全：全2册（下册）》", 31 March 2013, 湖北科学技术出版社 * |
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