CN107007700A - 一种活血化瘀的中药组合物及其制备方法 - Google Patents

一种活血化瘀的中药组合物及其制备方法 Download PDF

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CN107007700A
CN107007700A CN201710293943.1A CN201710293943A CN107007700A CN 107007700 A CN107007700 A CN 107007700A CN 201710293943 A CN201710293943 A CN 201710293943A CN 107007700 A CN107007700 A CN 107007700A
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赵成国
秦书芝
刘明石
张瑶
金元宝
李国成
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ZHUHAI ANSHENG FENGHUANG PHARMACEUTICAL CO Ltd
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Abstract

本发明公开了一种活血化瘀的中药组合物及其制备方法，该中药组合物由以下重量份的原料制备而成：川芎16‑24份、海马10‑15份、葛根15‑20份、白蔹10‑15份、三七18‑28份、自然铜(煅)5‑10份、朝鲜蓟11‑15份、独一味10‑20份、延胡索10‑20份、威灵仙10‑15份、白芍13‑17份、炙甘草5‑10份、当归6‑14份、大青叶3‑9份、丹参10‑20份。本发明通过药剂的合理配比，所得的组合物具有疏通经络、活血化瘀之效,以协助气血运行,使机体功能恢复的功效，且无毒副作用；采用药材提取浓缩的形式进行服用，使得药效得以充分发挥。

Description

一种活血化瘀的中药组合物及其制备方法
技术领域
本发明涉及中药制剂领域，具体涉及一种活血化瘀的中药组合物及其制备方法。
背景技术
中医认为，经络是人体气血的通路，如果经络不通畅，必然会导致机体发生各种病证；而血脉不通，血行不畅，则会引起疼痛甚至形成肿块等组织上的变化。所以疏通经络、活血化瘀对健康有着举足轻重的作用。
现有的中药养生大多以按摩保健或使用口服液、养生酒或者煎药等形式存在，疗效大打折扣，也没有结合其他养生固本的方法，效用发挥受到限制。
发明内容
为解决上述问题，本发明提供了一种活血化瘀的中药组合物及其制备方法，具有疏通经络、活血化瘀之效,以协助气血运行,使机体功能恢复的功效，且无毒副作用；采用药材提取浓缩的形式进行服用，使得药效得以充分发挥。
为实现上述目的，本发明采取的技术方案为：
一种活血化瘀的中药组合物，由以下重量份的原料制备而成：
川芎16-24份、海马10-15份、葛根15-20份、白蔹10-15份、三七18-28份、自然铜(煅)5-10份、朝鲜蓟11-15份、独一味10-20份、延胡索10-20份、威灵仙10-15份、白芍13-17份、炙甘草5-10份、当归6-14份、大青叶3-9份、丹参10-20份。
优选地，由以下重量份的原料制备而成：
川芎16份、海马10份、葛根15份、白蔹10份、三七18份、自然铜(煅)5份、朝鲜蓟11份、独一味10份、延胡索10份、威灵仙10份、白芍13份、炙甘草5份、当归6份、大青叶3份、丹参10份。
优选地，由以下重量份的原料制备而成：
川芎24份、海马15份、葛根20份、白蔹15份、三七28份、自然铜(煅)10份、朝鲜蓟15份、独一味20份、延胡索20份、威灵仙15份、白芍17份、炙甘草10份、当归14份、大青叶9份、丹参20份。
优选地，由以下重量份的原料制备而成：
川芎20份、海马12.5份、葛根17.5份、白蔹12.5份、三七23份、自然铜(煅)7.5份、朝鲜蓟13份、独一味15份、延胡索15份、威灵仙12.5份、白芍15份、炙甘草7.5份、当归10份、大青叶6份、丹参15份。
本发明还提供了上述活血化瘀的中药组合物的制备方法，包括如下步骤：
S1、按权利要求1-4任一项所述的配方称取各组分；
S2、将称取的川芎、海马、葛根、白蔹、三七、自然铜(煅)、朝鲜蓟、独一味、延胡索、威灵仙、白芍、炙甘草、当归、大青叶、丹参置于闪式提取器处理1-3分钟后，按药材质量百分比为0.5-2％的比例加入中性蛋白酶，30-50℃下酶解0.5-2h，过滤，得酶解液；
S3、将所得的酶解液迅速冷冻后再自然解冻，使提取物中淀粉老化沉淀；收集上清液，剩余部分离心，收集离心液体并合并于上清液中，浓缩，使得提取物呈稠膏状，再用水饱和正丁醇对提取物萃取3次，回收溶剂后，真空浓缩干燥，即得。
本发明具有以下有益效果：
通过药剂的合理配比，所得的组合物具有疏通经络、活血化瘀之效,以协助气血运行,使机体功能恢复的功效，且无毒副作用；采用药材提取浓缩的形式进行服用，使得药效得以充分发挥。
具体实施方式
为了使本发明的目的及优点更加清楚明白，以下结合实施例对本发明进行进一步详细说明。应当理解，此处所描述的具体实施例仅仅用以解释本发明，并不用于限定本发明。
实施例1
一种活血化瘀的中药组合物，由以下重量份的原料制备而成：
川芎16份、海马10份、葛根15份、白蔹10份、三七18份、自然铜(煅)5份、朝鲜蓟11份、独一味10份、延胡索10份、威灵仙10份、白芍13份、炙甘草5份、当归6份、大青叶3份、丹参10份。
实施例2
一种活血化瘀的中药组合物，由以下重量份的原料制备而成：
川芎24份、海马15份、葛根20份、白蔹15份、三七28份、自然铜(煅)10份、朝鲜蓟15份、独一味20份、延胡索20份、威灵仙15份、白芍17份、炙甘草10份、当归14份、大青叶9份、丹参20份。
实施例3
一种活血化瘀的中药组合物，由以下重量份的原料制备而成：
川芎20份、海马12.5份、葛根17.5份、白蔹12.5份、三七23份、自然铜(煅)7.5份、朝鲜蓟13份、独一味15份、延胡索15份、威灵仙12.5份、白芍15份、炙甘草7.5份、当归10份、大青叶6份、丹参15份。
本发明实施例还提供了一种活血化瘀的中药组合物的制备方法，包括如下步骤：
S1、按实施例1-实施例3所述的配方称取各组分；
S2、将称取的川芎、海马、葛根、白蔹、三七、自然铜(煅)、朝鲜蓟、独一味、延胡索、威灵仙、白芍、炙甘草、当归、大青叶、丹参置于闪式提取器处理1-3分钟后，按药材质量百分比为0.5-2％的比例加入中性蛋白酶，30-50℃下酶解0.5-2h，过滤，得酶解液；
S3、将所得的酶解液迅速冷冻后再自然解冻，使提取物中淀粉老化沉淀；收集上清液，剩余部分离心，收集离心液体并合并于上清液中，浓缩，使得提取物呈稠膏状，再用水饱和正丁醇对提取物萃取3次，回收溶剂后，真空浓缩干燥，即得。
以上所述仅是本发明的优选实施方式，应当指出，对于本技术领域的普通技术人员来说，在不脱离本发明原理的前提下，还可以作出若干改进和润饰，这些改进和润饰也应视为本发明的保护范围。

Claims (5)

1.一种活血化瘀的中药组合物，其特征在于，由以下重量份的原料制备而成：
川芎16-24份、海马10-15份、葛根15-20份、白蔹10-15份、三七18-28份、自然铜(煅)5-10份、朝鲜蓟11-15份、独一味10-20份、延胡索10-20份、威灵仙10-15份、白芍13-17份、炙甘草5-10份、当归6-14份、大青叶3-9份、丹参10-20份。
2.如权利要求1所述的一种活血化瘀的中药组合物，其特征在于，由以下重量份的原料制备而成：
川芎16份、海马10份、葛根15份、白蔹10份、三七18份、自然铜(煅)5份、朝鲜蓟11份、独一味10份、延胡索10份、威灵仙10份、白芍13份、炙甘草5份、当归6份、大青叶3份、丹参10份。
3.如权利要求1所述的一种活血化瘀的中药组合物，其特征在于，由以下重量份的原料制备而成：
川芎24份、海马15份、葛根20份、白蔹15份、三七28份、自然铜(煅)10份、朝鲜蓟15份、独一味20份、延胡索20份、威灵仙15份、白芍17份、炙甘草10份、当归14份、大青叶9份、丹参20份。
4.如权利要求1所述的一种活血化瘀的中药组合物，其特征在于，由以下重量份的原料制备而成：
川芎20份、海马12.5份、葛根17.5份、白蔹12.5份、三七23份、自然铜(煅)7.5份、朝鲜蓟13份、独一味15份、延胡索15份、威灵仙12.5份、白芍15份、炙甘草7.5份、当归10份、大青叶6份、丹参15份。
5.一种活血化瘀的中药组合物的制备方法，其特征在于，包括如下步骤：
S1、按权利要求1-4任一项所述的配方称取各组分；
S2、将称取的川芎、海马、葛根、白蔹、三七、自然铜(煅)、朝鲜蓟、独一味、延胡索、威灵仙、白芍、炙甘草、当归、大青叶、丹参置于闪式提取器处理1-3分钟后，按药材质量百分比为0.5-2％的比例加入中性蛋白酶，30-50℃下酶解0.5-2h，过滤，得酶解液；
S3、将所得的酶解液迅速冷冻后再自然解冻，使提取物中淀粉老化沉淀；收集上清液，剩余部分离心，收集离心液体并合并于上清液中，浓缩，使得提取物呈稠膏状，再用水饱和正丁醇对提取物萃取3次，回收溶剂后，真空浓缩干燥，即得。
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