CN107006855A - Composition and its preparation with the damage of reduction haze, clearing lung-heat and clearing effect - Google Patents
Composition and its preparation with the damage of reduction haze, clearing lung-heat and clearing effect Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8967—Lilium, e.g. tiger lily or Easter lily
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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Abstract
The present invention provides a kind of composition for having and reducing haze damage, clearing lung-heat and clearing effect, includes the following component of parts by weight：10 30 parts of Bulbus Lilii extract, 10 30 parts of snow pear extract, 20 30 parts of dried tremella extract, 10 30 parts of yam extract, 10 20 parts of carrot extract, 5 10 parts of Fructus Monordicae extract, 10 30 parts of Auricularia extract, 10 20 parts of grape seed extract, 10 20 parts of green-tea extract.The present invention is under the theoretical direction of the dietary therapy of Chinese medicine, optimal drug formula and consumption are obtained according to clinical many experiments screening, clinical trial shows, taking the composition in the present invention has effects that good clearing lung-heat shield lung, clearing resolving sputum, and hindering lung, bronchitis, chronic pharyngitis to haze has good therapeutic action.And clinical trial has no adverse reaction, security is good.
Description
Technical field
The invention belongs to field of health care food, and in particular to a kind of composition with effect of clearing away lung-heat.
Background technology
Human needs breathes air to sustain life, but with industrial fast development, and atmospheric environment is by serious
Pollution so that haze weather is more and more, situation is increasingly severe.It is micro- less than or equal to 2.5 containing many diameters in haze air
The particulate matter of rice, i.e. PM2.5.Compared with coarse granule and macroscopic dust, harm of the PM2.5 to health is bigger,
Blood can be entered by bronchus and alveolar, interference lung exchanges, cause respiratory tract infection, chronic pharyngitis, bronchitis and
A variety of diseases such as pneumonia.
Existing chemicals is main in terms for the treatment of haze is to diseases such as pulmonary lesion, respiratory tract infection, chronic pharyngitis
Treated by the way of anti-inflammation, can not improve and nurse one's health lung and the function of respiratory tract.In traditional Chinese medical science field, carry out
" clearing lung-heat " typically also has " yin-nourishing " effect when conditioning, it is therefore an objective to nourish yin-fluid, removes lung heat, lung-fire, is directed to clinical table
The patient for the symptom such as the few phlegm of existing dry cough, the dry spitting of blood of pharynx, cough and asthma, nasal cavity dryness lip be dry.For the angle of the traditional Chinese medical science, lily, pears etc.
The effect for truly having " moistening lung " of food, but air pollutants enter respiratory tract caused by recent environmental problems, in addition it is also necessary to other
The synergy of effect medicament.For thousands of years the history of traditional Chinese medicine and practice have shown that, the dietary therapy of Chinese medicine is in treatment haze damage, clear
There is unique advantage in terms of lung, clearing, side effect will not be brought as Western medicine, western medical treatment.Therefore, in the dietary therapy of Chinese medicine
Guidance under develop there is highly important meaning with health products, the nutriment for reducing haze damage, clearing lung-heat, clearing are acted on
Justice.
The content of the invention
The purpose of the present invention is there is provided one kind to reduce haze damage, with clearing lung-heat, clear the problem of presence for prior art
The composition and its preparation of pharynx effect.
The technical scheme for realizing above-mentioned purpose of the present invention is：
It is a kind of that there is the composition for reducing haze damage, clearing lung-heat and clearing effect, include the following component of parts by weight：
10-30 parts of Bulbus Lilii extract, 10-30 parts of snow pear extract, 20-30 parts of dried tremella extract, yam extract 10-30
Part, 10-20 parts of carrot extract, 5-10 parts of Fructus Monordicae extract, 10-30 parts of Auricularia extract, grape seed extract 10-20
Part, 10-20 parts of green-tea extract.
In this composition, lily and snow pear extract are the moistening lung food commonly used in the traditional Chinese medical science, play the work of moist respiratory tract
With.White fungus and agaric, which have effects that to remove, is adsorbed in structural particle, and the two amount added is approximate, synergy, than only
Add a kind of composition effect of agaric more notable.In this composition, carrot extract, grape seed extract, green-tea extract have
Remove free radical, strengthen effect of human immunological competence, not only act as the effect of taking stopgap measures of moistening lung, and it is real from body-building angle
The effect now effected a permanent cure.Momordica grosvenori is one of medicine-food two-purpose material that country ratifies in the first batch, and its primary efficacy is can be relieving cough and reducing sputum.Sieve
Chinese berry extract is to extract the solid particle that Momordica grosvenori is obtained with polar solvent (ethanol), in the nutrition for keeping fresh fruit simultaneously, is gone back
Sweet mouthfeel can be brought to beverage.
Preferably, the active ingredient of the composition is composed of the following components in parts by weight：24 parts of Bulbus Lilii extract, pyrus nivalis
26 parts of extract, 25 parts of dried tremella extract, 25 parts of yam extract, 15 parts of carrot extract, 7 parts of Fructus Monordicae extract, agaric
23 parts of extract, 15 parts of grape seed extract, 15 parts of green-tea extract.
Further, the composition is made up of the composition of following parts by weight：10-30 parts of Bulbus Lilii extract, pyrus nivalis is extracted
10-30 parts of thing, 20-30 parts of dried tremella extract, 10-30 parts of yam extract, 10-20 parts of carrot extract, Fructus Monordicae extract
5-10 parts, 10-30 parts of Auricularia extract, 10-20 parts of grape seed extract, 10-20 parts of green-tea extract, 10-20 parts of prebiotics；
The prebiotics (Probiotics) is isomalto-oligosaccharide, FOS or xylo-oligosaccharide；
Prebiotics is to prepare auxiliary material used, will not produce shadow to effect in terms of reducing haze damage, clearing lung-heat and clearing
Ring.
Wherein, the formulation of the composition is one kind in granule, pulvis, capsule, tablet.Combination of the present invention
Powder, all food sources are made in the conventional method that thing can be grasped using those skilled in the art, and press actual demand system
It is suitable for people of all ages into various formulations, such as granule, pulvis, capsule, tablet, it can be had no toxic side effect with long-term taking.
Further, the formulation of the composition is granule, and the preparation method of the composition includes step：
1) each composition for constituting the composition active ingredient is sieved, chosen under 60-100 mesh sieves, then according to proportioning
Each composition is weighed, is well mixed；
2) fine powder mixed is added into adhesive, by oscillating granulator, the particle of 10-60 mesh is made, is in temperature
It is dried under conditions of 40-60 DEG C, drying time 30-90 minute, dispenses, produce.
The consumption of the binding agent is the 2%-5% of remaining each component quality sum.
Wherein, the alcohol that the binding agent is water or volumetric concentration is 10-95%.
Composition of the present invention is being prepared with the damage of reduction haze, clearing lung-heat, the functional food of clearing effect and guarantor
Application in health food.
The beneficial effects of the present invention are：
1st, the present invention is under the theoretical direction of the dietary therapy of Chinese medicine, according to clinical many experiments screening obtain optimal drug formula and
Consumption, clinical trial shows that taking the composition in the present invention has effects that good clearing lung-heat shield lung, clearing resolving sputum, to mist
Haze, which hinders lung, bronchitis, chronic pharyngitis, has good therapeutic action.And clinical trial has no adverse reaction, security is good.
2nd, after the product that the present invention is provided is reconstituted, color coordination, sweet mouthfeel is moderate, and is food-borne composition, nothing
Toxicity, side effect, can safety, long-term taking, it is suitable for people of all ages.
Embodiment
Following examples are used to illustrate the present invention, but are not limited to the scope of the present invention.
The Bulbus Lilii extract is extracted by the fleshy scale leaf of lily employed in the embodiment of the present invention, polyoses content >=
20%；Snow pear extract is extracted by fresh pears, its polyoses content >=20%；Dried tremella extract is extracted by white fungus, and it is more
Sugared content >=20%, yam extract is extracted by the dry rhizome of Chinese yam, its Chinese yam saponin >=10%, carrot extract
Middle content beta-carotene reaches that mogroside content reaches more than 10% in more than 2%, Fructus Monordicae extract, and the agaric carries
Polyoses content >=20% in thing is taken, grape seed extract main component is OPC, and its content reaches more than 95%.Green tea is carried
The main component for taking thing is polyphenol, and its content reaches more than 80%, and above extract is powder, natural purchased from Tianjin spike
Study on product development corporation, Ltd..
In embodiment, unless otherwise specified, used means are this area conventional technology.
Embodiment 1
Haze damage, the composition acted on clearing lung-heat, clearing are reduced, is made up of the raw material of following masses number：Lily
24 parts of extract, 26 parts of snow pear extract, 25 parts of dried tremella extract, 25 parts of yam extract, 15 parts of carrot extract, arhat
7 parts of berry extract, 23 parts of Auricularia extract, 15 parts of grape seed extract, 15 parts of green-tea extract.
This composition is granule, and preparation method is：
1) above-mentioned each composition is sieved, chooses under 80 mesh sieves, then weigh each composition according to proportioning, be well mixed；
2) fine powder mixed is added into adhesive (alcohol of volumetric concentration 10%), the consumption of adhesive is each group sub-prime
The 3% of sum is measured, by oscillating granulator, the particle of 10-60 mesh is made, is dried, does under conditions of temperature is 60 DEG C
Dry 60 minutes time, packing is produced.
Embodiment 2
Haze damage, the composition acted on clearing lung-heat, clearing are reduced, is made up of the raw material of following masses number：Lily
30 parts of extract, 30 parts of snow pear extract, 30 parts of dried tremella extract, 30 parts of yam extract, 20 parts of carrot extract, arhat
10 parts of berry extract, 30 parts of Auricularia extract, 20 parts of grape seed extract, 20 parts of green-tea extract.
Preparation method be the same as Example 1.
Embodiment 3
Haze damage, the composition acted on clearing lung-heat, clearing are reduced, is made up of the raw material of following masses number：Lily
10 parts of extract, 10 parts of snow pear extract, 20 parts of dried tremella extract, 10 parts of yam extract, 10 parts of carrot extract, arhat
5 parts of berry extract, 10 parts of Auricularia extract, 10 parts of grape seed extract, 10 parts of green-tea extract.
Preparation method be the same as Example 1.
Taste test
Embodiment 1-3 10 grams of granule is one, plus 50mL hot water, and the people of subject 20, age and sex are random.
Subject has drunk embodiment 1,2,3 made beverages respectively, and the mouthfeel of embodiment 1,2,3 is fresh and sweet, without flavour of a drug, by
Like to drinking person.
Clinical research is tested
First, diagnostic criteria
Western medicine diagnostic criteria：Formulated with reference to Chinese Medical Association's respirology meeting asthma group《The Clinics and Practices of cough
Guide》In diagnostic criteria draft.
Tcm diagnosis standard：According to《Chinese Internal Medicine》And《Diagnostics of Chinese Medicine》In exogenous cough's disease type standard draft.
Ailment said due to cold or exposure love lung card：Primary symptom：Cough, mostly paroxysmal cough is coughed and itched；Secondary disease：Phlegm is few, and color white matter is sticked；Tongue fur：Pink tongue, tongue
Bao Bai；Pulse condition：Pulse condition is floating slow.Diagnostic criteria：Primary symptom+secondary disease, or primary symptom add tongue vein i.e. diagnosable.
2nd, experimental method
1st, case selection：Clinical disease shows as cough, the patient 160 of lung heat, is divided into treatment group 80, control group 80
Example, this two groups of cases in terms of severity extent, sex, age, the course of disease substantially close to.
2nd, treatment method：The composition in embodiment 1 is taken by treatment group, and 1 dose every time, 2 times a day.Continuously take 2 weeks；It is right
Pseudoephedrine hydrochloride solution (Hui Shi-hundred palaces pharmaceutical Co. Ltd) is taken according to group, orally, each 10ml, 3 times a day, continuously takes 2
Week.
3rd, experimental result
Two groups of efficacy results are as shown in table 1.By table 1 test result indicates that, the composition that provides of the present invention, i.e. treatment group
Total effective rate is 95%, and control group total effective rate is 52.5%, show the composition that provides of the present invention have well treatment lung heat,
Effect of cough.
The composition of 1 embodiment of table 1 is to cough, the therapeutic effect of lung heat patient
| Packet | Number of cases | It is effective | Effectively | It is invalid | Obvious effective rate | Total effective rate |
| Control group | 80 | 64 | 12 | 4 | 80% | 95% |
| Treatment group | 80 | 22 | 20 | 38 | 27.5% | 52.5% |
Above clinical trial results show, the composition provided in the present invention have moisturize well clearing lung-heat, it is relieving cough and reducing sputum,
Clear relieving sore-throat palate, has good preventive and therapeutic effect to lung heat injury of lungs, cough and expectoration, chronic pharyngitis caused by haze.And it is clinical
Observation there are no adverse reaction, and security is good.
Although above the present invention is described in detail with a general description of the specific embodiments,
On the basis of the present invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Cause
This, these modifications or improvements, belong to the scope of protection of present invention without departing from theon the basis of the spirit of the present invention.
Claims (7)
1. a kind of have the composition for reducing haze damage, clearing lung-heat and clearing effect, it is characterised in that following including parts by weight
Composition：
10-30 parts of Bulbus Lilii extract, 10-30 parts of snow pear extract, 20-30 parts of dried tremella extract, 10-30 parts of yam extract,
10-20 parts of carrot extract, 5-10 parts of Fructus Monordicae extract, 10-30 parts of Auricularia extract, 10-20 parts of grape seed extract,
10-20 parts of green-tea extract.
2. composition according to claim 1, it is characterised in that the active ingredient of the composition is by following parts by weight
Composition is constituted：24 parts of Bulbus Lilii extract, 26 parts of snow pear extract, 25 parts of dried tremella extract, 25 parts of yam extract, carrot carries
Take 15 parts of thing, 7 parts of Fructus Monordicae extract, 23 parts of Auricularia extract, 15 parts of grape seed extract, 15 parts of green-tea extract.
3. composition according to claim 1, it is characterised in that the composition is made up of the composition of following parts by weight：
10-30 parts of Bulbus Lilii extract, 10-30 parts of snow pear extract, 20-30 parts of dried tremella extract, 10-30 parts of yam extract, carrot
10-20 parts of extract, 5-10 parts of Fructus Monordicae extract, 10-30 parts of Auricularia extract, 10-20 parts of grape seed extract, green tea is carried
Take 10-20 parts of thing, 10-20 parts of prebiotics；
The prebiotics (Probiotics) includes the one or more in isomalto-oligosaccharide, FOS or oligomeric wood.
4. the composition according to any one of claims 1 to 3, it is characterised in that the formulation of the composition be granule,
One kind in pulvis, capsule, tablet.
5. the composition according to any one of claims 1 to 3, it is characterised in that the formulation of the composition is granule,
The preparation method of the composition includes step：
1) composition for constituting the composition is sieved, chooses under 60-100 mesh sieves, then weigh each composition according to proportioning, mixed
Uniformly；
2) fine powder mixed is added into binding agent, by oscillating granulator, the particle of 10-60 mesh is made, be 40-60 in temperature
It is dried under conditions of DEG C, drying time 30-90 minute, dispenses, produce.
6. composition according to claim 5, it is characterised in that the binding agent is water or volumetric concentration is 10-95%
Alcohol, the consumption of the binding agent is the 2%-5% of remaining each component quality sum.
7. the composition described in any one of claim 1~6 is being prepared with the work(for reducing haze damage, clearing lung-heat, clearing effect
Application in energy food and health food.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710155017.8A CN107006855A (en) | 2017-03-15 | 2017-03-15 | Composition and its preparation with the damage of reduction haze, clearing lung-heat and clearing effect |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710155017.8A CN107006855A (en) | 2017-03-15 | 2017-03-15 | Composition and its preparation with the damage of reduction haze, clearing lung-heat and clearing effect |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107982415A (en) * | 2017-12-06 | 2018-05-04 | 吕景峰 | A kind of haze oral liquid for clearing away lung-heat |
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| CN105267608A (en) * | 2015-11-17 | 2016-01-27 | 雷少华 | Composition for clearing lungs and removing dust |
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| CN104587249A (en) * | 2015-01-12 | 2015-05-06 | 曹成瑞 | Traditional Chinese medicine composition with effects of clearing lung, moistening dryness and relieving sore throat as well as preparation method and application thereof |
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