CN106983144A - A kind of deep processing health-care food composition for treating constipation - Google Patents
A kind of deep processing health-care food composition for treating constipation Download PDFInfo
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- CN106983144A CN106983144A CN201710236798.3A CN201710236798A CN106983144A CN 106983144 A CN106983144 A CN 106983144A CN 201710236798 A CN201710236798 A CN 201710236798A CN 106983144 A CN106983144 A CN 106983144A
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- radish seed
- constipation
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G2200/00—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents
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Abstract
The present invention relates to technical field of health care food, more particularly to a kind of deep processing health-care food composition for treating constipation.The health-care food composition is made up of mulberries extract and radish seed extract.Mulberries extract and radish seed extract compatibility can be effectively improved the constipation symptom of the elderly by health-care food composition of the present invention after, and effect is better than the effect that mulberries extract or radish seed extract are used alone, with synergistic function.Pressed candy of the present invention does not stick to one's teeth, and easily chews;The not sticking in tableting processes, compressibility is good, and candy surface is smooth.
Description
Technical field
The present invention relates to technical field of health care food, more particularly to a kind of deep processing health food combination for treating constipation
Thing.
Background technology
Constipation is clinically more typical symptom of digestive tract, refers to that excrement is detained too long in enteral, constipated obstructed, defecation week
Phase extends, or the cycle is not long, and excrement matter is dry and hard, and it is difficult to discharge, or excrement matter is not hard, though there is awareness of defecation, but just without smooth disease.Work(
Energy property constipation (Functional Constipation, FC) is to exclude enteron aisle, whole body organic disease and drug induced constipation
Outside the functional disease using constipation as main disease, and can be with the symptom such as abdominal distension, dry, weak, burnout.Functional consitipation is again
It is divided into constipation of slow-remove type and export-oriented constipation and mixed constipation.Contemporary society, dog-eat-dog causes operating pressure excessive, ring
Border and psychological factor cause bowl evacuation habit to change, living standard improve after dietary structure great changes will take place (meat based on, feed
It is excessively fine) etc. reason cause the constipation incidence of disease be in significantly raised trend, have a strong impact on the quality of life of people.
Reported according to domestic and foreign literature, the incidence of disease of constipation is 5%~25% for the whole world, China's incidence of disease is 10%
~15%, more than 60 years old the elderly accounts for the 18%~23% of morbidity crowd.Age of onset statistics shows that first peak is appeared in
30~39 years old, age of onset is pointed out to have rejuvenation trend, M-F 1:4.59.If using the main suit of " difficult defecation " as just
Secret evaluation criteria, the incidence of disease can substantially exceed 50%.Clinically, functional consitipation accounts for more than the 50% of constipation.It is reported that
Its crowd's total incidence is 6.07%~14.7%, and over-65s the elderly's illness rate is up to 40.2%.With reference to clinical general trend
It is higher than young people for the elderly, women is more than male.Wherein in functional consitipation, constipation of slow-remove type accounts for 45.5%.
Constipation of slow-remove type major clinical feature be Colonic transit motion slow down, intestinal contents by delaying, it is bright without awareness of defecation, defecation frequency
Aobvious to reduce, auxiliary examination confirms to have that full stomach and intestine or Colon absorption delay or colonic activity is low.
Constipation plays an important role in the generation of some diseases, such as acne, mammary gland disease, alzheimer's disease, aging;More
It may cause or aggravate other diseases, such as hypertension, acute myocardial infarction, cerebrovas-cularaccident.Even there is scholar to think just in recent years
It is secret it is long-term it is refractory may make enteral carcinogenic substance extended residence time, increase the morbidity chance of colorectal cancer.
It currently there are the medicine of more treatment constipation, but middle-aged and old constipation or the such medicine of long-term taking
If be easily caused more side effect, or even cause diarrhoea, stomachache, intestines problem etc..So far still lacking preferably improves
The health products of constipation of old people.
The content of the invention
In view of this, the invention provides a kind of deep processing health-care food composition for treating constipation.The health food group
Compound can be effectively improved the constipation symptom of the elderly, and effect is better than the effect that mulberries extract or radish seed extract are used alone
Really.
In order to realize foregoing invention purpose, the present invention provides following technical scheme:
The invention provides a kind of health-care food composition, it is made up of mulberries extract and radish seed extract.
Radish seed extract:According to《Compendium of Materia Medica》Record, radish seed have lower gas Dingchuan, control phlegm, help digestion, de-swelling, profit
Stool and urine acts on;The main body of consumption crowd of this product is the elderly, and habitual constipation is a kind of common disease of the elderly.It is old
People is because the deficiency of qi in middle-jiao, visceral dysfunction, body fluid are short, large intestine loses and moistens, causes constipation the development of evil in febrile disease is powerless, belongs to the withered constipation in Tianjin.Clinically use
Radish seed treatment senility habitual constipation has good curative effect.
Fructus Mori extract:Traditional Chinese Medicine thinks, mulberry fruit has enriching yin, tonifying liver, kidney tonifying, enriches blood, item, blacking hair and nourishing face, controls
Treat insomnia and neurasthenia, it is antifatigue, anti-the effects such as treat constipation.Modern medicine study shows, mulberry fruit have enhancing immunologic function,
Promote the growth of hematopoietic cell, prevent human body artery hardening, anti-mutagenesis, hypoglycemic, antiviral, anti-oxidant and continuity aging etc. from making
With.
Present invention research finds mulberries extract and radish seed extract compatibility can significantly improve the elderly after
Constipation symptom, effect is better than the effect that mulberries extract or radish seed extract are used alone.Result of study shows that mulberries are carried
Take thing and radish seed extract that there is synergistic function.
Preferably, the mass ratio of mulberries extract and radish seed extract is (5~15):(3~6).
In the specific embodiment that the present invention is provided, the mass ratio of mulberries extract and radish seed extract is 5:6.
In the another specific embodiment that the present invention is provided, the mass ratio of mulberries extract and radish seed extract is 12:
4。
In the another specific embodiment that the present invention is provided, the mass ratio of mulberries extract and radish seed extract is 15:
3。
Preparing the medicine for the treatment of person in middle and old age's constipation present invention also offers the health-care food composition or improving person in middle and old age
Application in the health products of constipation.
Present invention also offers a kind of pressed candy, including mulberries extract, radish seed extract, isomalt,
Oligosaccharide, common oats fibre and magnesium stearate.
Oligosaccharide:FOS, xylo-oligosaccharide belong to prebiotics, and prebiotics is the food ingredients not being digested, Ke Yixuan
Selecting property promote colon in a kind of or a few bacterium growth or activity and to host produce beneficial effect.The work of prebiotics
With mainly having:By adsorbing enteric pathogenic bacteria in alimentary canal, it is promoted to be discharged with excrement, while also having defecating feces excretion;Quilt
Intestinal beneficial flora is utilized, and promotes its growth and breeding, forms Tiny ecosystem competitive advantage, while some of beneficial bacterial metabolic generation resist
Fungus matter and short chain fatty acids directly suppress the growth of exogenous pathogenic bacteria and the rotten bacterium of intestines, reduce the generation of noxious material;Stimulate
Immune response, improves the immunity of body;Improve intestinal environment, prevent diarrhoea.Flora knot in all ages and classes colony enteron aisle
Structure is different;Different prebioticses are different to the impact effect of probiotics, prebiotics of the same race to the action effects of different probiotics not yet
Together.Compared to other prebioticses, FOS can remarkably promote the growth of bifidobacterium infantis;And xylo-oligosaccharide relatively tends to
Promote long bifid, bifidobacterium adolescentis;Both are used in combination, and reach the effect that collaboration promotes.
FOS, xylo-oligosaccharide also have the advantage that:
1. low carious tooth:Carious tooth is mainly Streptococcus mutans etc. and sugar is generated into water-insoluble glucan, and is adhered to tooth
Surface forms tartar.Acid-producing bacteria in oral cavity is attached to tartar top fermentation production acid, dissolves the inanimate matter of tooth, causes carious tooth.
Oligosaccharide can not be by Streptococcus mutans etc. by the use of as the energy, and the glucosyl transferase that the bacterium produces can not be by oligosaccharide generation not
The glucan of dissolubility and adherence.Oral cavity acid-producing bacteria ferments oligomeric glycogenetic lactic acid also far below the acid of fermentation sucrose generation.
It is reported that oligosaccharide is difficult to make carious tooth pathogen aggegation, its lactic acid production generated on the flank of tooth is lower than sucrose by 23%~50%, dental caries
Rate is well below sucrose.
2. indigestibility, low in calories:Oligosaccharide is not hydrolyzed by the enzyme in human saliva and small intestine digestive ferment, it is difficult to disappeared
Change and absorb, be only capable of by Bifidobacterium selective use in large intestine, its tunning is short chain fatty acids, is difficult to be digested absorption,
And calorie value is low, there is similar water-soluble dietary fiber, be difficult to cause obesity.
3. blood glucose is not influenceed:Intake FOS, xylo-oligosaccharide will not cause blood glucose value and insulin to raise, to by pancreas islet
The synthesis of the hepatic glycogen of element control is diabetes and edible for patients with elevated blood pressure also without influence.
Common oats fibre:1. relax bowel:Different from the prebiotics such as oligosaccharide and water-soluble dietary fiber, common oats fibre is not
Soluble dietary fiber, with very strong water holding capacity, is not absorbed by alimentary canal, but can absorb large quantity of moisture and swollen in large intestine
Swollen, softer stool strengthens enterocinesia, stimulates intestinal wall to produce awareness of defecation sense, accelerates the discharge of stool, reaches the purpose relaxed bowel;
2. control body weight:Common oats fibre has the distinctive increase-volume of dietary fiber, water holding, holds the effect of oil, can after the water suction of stomach enteral
Make stomach, enterectasis, produce satiety, reduce food-intake.The low heat value of other dietary fiber, is particularly conducive to fat-reducing personage's control
Body weight.
Pressed candy of the prior art has stronger adhesiveness, and is difficult to chew, and have impact on the use of pressed candy
Crowd, especially for the elderly.The present invention with the addition of after common oats fibre, can effectively improve fructose stick to one's teeth performance and
Hardness, more suitable for the elderly, especially for the elderly with constipation.
Meanwhile, inventor has found that mulberries extract is sensitive to hot pressing in preparation process, is easily generated heat during tabletting so that pressure
There is the phenomenon of sticking mould during piece, product is difficult to come off from mould.Inventor is it was unexpectedly observed that after addition common oats fibre, pressing
Without sticking mould phenomenon during piece, pressed candy easily comes off from mould, the sticking to mould when addition of common oats fibre is for tabletting
Phenomenon also has greatly improved.
Isomalt:Compared with sucrose or white granulated sugar, isomalt have relatively low sugariness, low carious tooth,
It is low in calories, the features such as do not influence blood glucose.
Preferably, in parts by weight, each component consumption is:5~15 parts of mulberries extract, radish seed extract 3~6
Part, 25~40 parts of isomalt, 30~36 parts of oligosaccharide, 4~8 parts of common oats fibre, 0.5~1.5 part of magnesium stearate.
In the specific embodiment that the present invention is provided, in parts by weight, each component consumption is:6 parts of mulberries extract, Lay
5 parts of Fu seed extracts, 36 parts of isomalt, 32 parts of oligosaccharide, 5 parts of common oats fibre, 0.7 part of magnesium stearate.
In the another specific embodiment that the present invention is provided, in parts by weight, each component consumption is:Mulberries extract 12
Part, 4 parts of radish seed extract, 28 parts of isomalt, 30 parts of oligosaccharide, 5 parts of common oats fibre, 0.7 part of magnesium stearate.
Preferably, radish seed extract is Semen Raphani (parched) extract.
Preferably, oligosaccharide is FOS and/or xylo-oligosaccharide.
Preferably, oligosaccharide is the mixture of FOS and xylo-oligosaccharide.
In the specific embodiment that provides of the present invention, in the mixture of FOS and xylo-oligosaccharide, FOS with
The mass ratio of xylo-oligosaccharide is 1:1.But the mass ratio of the two is not limited to this, any ratio can reach of the invention specific
The close effect of embodiment.
In the embodiment that the present invention is provided, isomalt is isomalt particle.
Preferably, the pressed candy also includes compounding fruit glaze agent.
Preferably, in parts by weight, each component consumption is:5~15 parts of mulberries extract, radish seed extract 3~6
Part, 25~40 parts of isomalt, 30~36 parts of oligosaccharide, 4~8 parts of common oats fibre, 0.5~1.5 part of magnesium stearate, compounding
0.2~1 part of fruit glaze agent.
In the specific embodiment that the present invention is provided, in parts by weight, each component consumption is:6 parts of mulberries extract, Lay
5 parts of Fu seed extracts, 36 parts of isomalt, 32 parts of oligosaccharide, 5 parts of common oats fibre, 0.7 part of magnesium stearate compounds envelope
0.4 part of agent.
In the another specific embodiment that the present invention is provided, in parts by weight, each component consumption is:Mulberries extract 12
Part, 4 parts of radish seed extract, 28 parts of isomalt, 30 parts of oligosaccharide, 5 parts of common oats fibre, 0.7 part of magnesium stearate, compounding
0.42 part of fruit glaze agent.
Present invention also offers the preparation method of the pressed candy, comprise the following steps:
Mulberries extract, radish seed extract, isomalt, oligosaccharide, common oats fibre and magnesium stearate are mixed,
Tabletting, obtains pressed candy.
In order to obtain preferable tabletting effect, it is to avoid sticking or unilateral hollow, rough, in tableting processes, as excellent
Choosing, tabletting controls humidity to be 25%~45%.
Preferably, tabletting controls humidity to be 33%~37%.
In the specific embodiment that the present invention is provided, the humidity of tabletting is 35%.
Preferably, the step of also including being coated after tabletting.
In the embodiment that the present invention is provided, it is coated and is coated using compounding fruit glaze agent.
The invention provides a kind of health-care food composition and pressed candy for treating constipation.The health-care food composition by
Mulberries extract and radish seed extract composition.The present invention one of has the advantages that:
(1) mulberries extract and radish seed extract compatibility can be effectively improved by health-care food composition of the present invention after
The constipation symptom of the elderly, effect is better than the effect that mulberries extract or radish seed extract are used alone, and increases with collaboration
Effect is acted on.
(2) pressed candy has stronger adhesiveness, and is difficult to chew, and pressed candy of the present invention with the addition of common oats fibre
Afterwards, stick to one's teeth performance and the hardness of fructose can effectively be improved, more suitable for the elderly, candy slowly dissolves, and taste is mellow,
Good in taste, aftertaste sense is strong.
(3) compatibility of pressed candy raw material selection prebiotics of the present invention, insoluble diedairy fiber and Chinese medical extract, respectively
Using modern medicine and Traditional Chinese medical theory mechanism, gut flora is on the one hand adjusted by prebiotics, insoluble diedairy fiber, promoted
Enter intestinal peristalsis, reach quick improvement diarrhoea or the purpose of constipation;On the other hand by enriching the blood to restore normal menstruation method, improve because gas is cloudy not
Foot, dryness-heat stagnating in the interior, internal organs gas is not smooth, habitual constipation caused by deficiency of vital energy body fluid deficiency, liver kidney asthenia of essence and blood, is treated both principal and secondary aspect of disease so as to reach
Purpose.
(4) hygroscopicity of pressed candy primary raw material mulberries extract of the present invention is stronger, in tableting processes, easily occurs
Sticking, on the one hand can influence the outward appearance and quality of product, cause surface hollow, rough, be on the one hand easily caused drift or set
It is standby to damage.Humidity is high or low all to cause the problems such as sticking, poor product quality, low production efficiency occurs in pressed candy.The present invention
Found by studying, control tabletting ambient humidity, it becomes possible to preferably improve the sticking problem that tabletting is produced, appearance yield
Significantly improve.
(5) pressed candy raw material compressibility of the present invention is poor, and poor compressibility can be solved the problems, such as by wet granulation, but together
When product hardness can raise, be unfavorable for the elderly and chew edible, the present invention, which passes through to study, to be found, selects suitable supplementary product kind
Isomaltose sugar alcohol and graininess, can preferably improve the compressibility of pressed candy, while hardness will not be too high.
Embodiment
The invention discloses a kind of health-care food composition and pressed candy for treating constipation, those skilled in the art can be with
Present disclosure is used for reference, technological parameter realization is suitably modified.In particular, all similar replacements and change are to ability
It is it will be apparent that they are considered as being included in the present invention for field technique personnel.The method of the present invention and application have been led to
Cross preferred embodiment to be described, related personnel substantially can be not departing from present invention, in spirit and scope to this paper institutes
The methods and applications stated are modified or suitably change is with combining, to realize and apply the technology of the present invention.
In the specific embodiment that the present invention is provided, the preparation method of pressed candy is as follows:
1st, weigh and get the raw materials ready.
Semen Raphani (parched) extract, Fructus Mori extract, FOS, xylo-oligosaccharide, isomalt particle input is mixed
In conjunction machine, dog-house is covered with supporting closure, confirms to open mixer mixing 15-25 minutes, setting speed 8 after sealing
Rev/min, then common oats fibre is put into, 10-22 revs/min of setting speed is mixed 4-7 minutes, then puts into magnesium stearate mixing 5min, extremely
Mixed material uniform color, discharging.
2nd, tabletting.
Material is placed in tablet press machine hopper or after vacuum intake, tabletting electromechanical source is opened, sets pressure, rotating speed,
It is 25%-45% to control humidity range, carries out tabletting.
3rd, it is coated.
Raw materials used or auxiliary material can be by the health-care food composition and pressed candy of the treatment constipation that the present invention is provided
Market is bought.Mulberries extract, radish seed extract can make acquisition by oneself, also be commercially available.
With reference to embodiment, the present invention is expanded on further:
Test example 1
1st, experiment packet:
Test group 1:6 parts of 5 parts+radish seed extract of mulberries extract;
Test group 2:4 parts of 12 parts+radish seed extract of mulberries extract;
Test group 3:3 parts of 15 parts+radish seed extract of mulberries extract;
Control group 1:Mulberries extract;
Control group 2:Radish seed extract;
Control group 3:Blank;
Control group 4:9 parts of 2 parts+radish seed extract of mulberries extract;
Control group 5:1 part of 18 parts+radish seed extract of mulberries extract.
2nd, test method:
Tested using human experiment, select 160 volunteers, the age is 55-60 Sui, and constipation symptom is similar, at random
It is divided into 8 groups, (the above-mentioned sample in addition to blank group passes through conventional pressure to 7 groups of subjects taking each group sample during testing daily
Blade technolgy is made, and the relative usage of the active principle in each tablet is identical), dosage is conventional effective dose, and 4 tablet per days take altogether
With 28d, control group 3 does not take any sample, the original Diet lifestyle of subject is not changed during 8 groups of subject's experiments.
Observation index and test method are as follows:Defecation condition is investigated, and according to difficult defecation degree, can be divided into 1-4 grades, 1 grade
Normal for defecation, 2 grades are only bearing down, sense of discomfort, 3 grades be bearing down, sense of discomfort substantially, or have just frequency but a difficult defecation and
And amount is few, 4 grades are often stomachache or anus burn feeling, influence defecation.1-4 grades are designated as 1-4 points respectively.
Fecal character is investigated:Fecal character is divided into 1-3 grades according to Bristol fecal character classification, 1 grade is as fragrant
Intestines or snake, it is smooth and soft;Soft agglomerate, but be easily drained;2 grades are sausage character but agglomerate, loose bulk, as mud
The excrement of shape;3 grades of hard groups for separation, as fruit stone, should not discharge.1-3 grades are designated as 1-3 points respectively.
3rd, experimental result:
The defecation condition and faecal condition of each group of table 1
Group | Defecation frequency (times/week) | Defecation condition | Faecal condition |
Test group 1 | 5.56±0.21 | 1.78±0.19 | 1.76±0.23 |
Test group 2 | 5.76±0.27 | 1.68±0.25 | 1.87±0.15 |
Test group 3 | 5.84±0.31 | 1.65±0.23 | 1.80±0.26 |
Control group 1 | 4.12±0.22 | 2.32±0.26 | 2.25±0.31 |
Control group 2 | 4.45±0.27 | 2.43±0.15 | 2.15±0.27 |
Control group 3 | 3.17±0.67 | 2.89±0.32 | 2.57±0.31 |
Control group 4 | 4.76±0.22 | 2.01±0.13 | 2.08±0.11 |
Control group 5 | 4.83±0.12 | 2.03±0.15 | 2.10±0.10 |
The experimental data of table 1 shows that defecation frequency, defecation condition, faecal condition are respectively provided with statistical significance, take test group
After 1-3 product, obvious improvement, i.e. product of the invention are respectively provided with terms of defecation frequency, defecation condition and faecal condition
Constipation can effectively be improved, and effect is better than each single dose.
Embodiment 1
Formula:36 parts of isomalt particle, 32 parts of oligosaccharide (wherein, 16 parts of FOS, 16 parts of xylo-oligosaccharide),
6 parts of mulberries extract, 5 parts of common oats fibre, 5 parts of radish seed extract, 0.7 part of magnesium stearate, 0.4 part of fruit glaze agent of compounding.
The specific method of pressed candy is:
1st, weigh and get the raw materials ready.
Semen Raphani (parched) extract, Fructus Mori extract, FOS, xylo-oligosaccharide, isomalt particle input is mixed
In conjunction machine, dog-house is covered with supporting closure, confirms to open mixer mixing 15-25 minutes, setting speed 8 after sealing
Rev/min, then common oats fibre is put into, 10-22 revs/min of setting speed is mixed 4-7 minutes, then puts into magnesium stearate mixing 5min, extremely
Mixed material uniform color, discharging.
2nd, tabletting.Material is placed in tablet press machine hopper or after vacuum intake, tabletting electromechanical source is opened, sets pressure
Power, rotating speed, it is 33-37% to control humidity range, carries out tabletting.
3rd, it is coated.
Embodiment 2
Formula:28 parts of isomalt particle, 30 parts of oligosaccharide (wherein, 15 parts of FOS, 15 parts of xylo-oligosaccharide),
12 parts of mulberries extract, 5 parts of common oats fibre, 4 parts of radish seed extract, 0.7 part of magnesium stearate, 0.42 part of fruit glaze agent of compounding.
The specific method of pressed candy is:
1st, weigh and get the raw materials ready.
Semen Raphani (parched) extract, Fructus Mori extract, FOS, xylo-oligosaccharide, isomalt particle input is mixed
In conjunction machine, dog-house is covered with supporting closure, confirms to open mixer mixing 15-25 minutes, setting speed 8 after sealing
Rev/min, then common oats fibre is put into, 10-22 revs/min of setting speed is mixed 4-7 minutes, then puts into magnesium stearate mixing 5min, extremely
Mixed material uniform color, discharging.
2nd, tabletting.Material is placed in tablet press machine hopper or after vacuum intake, tabletting electromechanical source is opened, sets pressure
Power, rotating speed, it is 33-37% to control humidity range, carries out tabletting.
3rd, it is coated.
Comparative example 1
Formula:36 parts of isomalt particle, 32 parts of oligosaccharide (wherein, 16 parts of FOS, 16 parts of xylo-oligosaccharide),
6 parts of mulberries extract, 5 parts of radish seed extract, 0.7 part of magnesium stearate, 0.4 part of fruit glaze agent of compounding.Compared with Example 1, not
Add common oats fibre.
The specific method of pressed candy is:
1st, weigh and get the raw materials ready.
Semen Raphani (parched) extract, Fructus Mori extract, FOS, xylo-oligosaccharide, isomalt particle input is mixed
In conjunction machine, dog-house is covered with supporting closure, confirms to open mixer mixing 15-25 minutes, setting speed 8 after sealing
Rev/min, then magnesium stearate mixing 5min is put into, to mixed material uniform color, discharging.
2nd, tabletting.Material is placed in tablet press machine hopper or after vacuum intake, tabletting electromechanical source is opened, sets pressure
Power, rotating speed, it is 33-37% to control humidity range, carries out tabletting.
3rd, it is coated.
Comparative example 2
Formula:28 parts of isomalt particle, 30 parts of oligosaccharide (wherein, 15 parts of FOS, 15 parts of xylo-oligosaccharide),
12 parts of mulberries extract, 5 parts of common oats fibre, 4 parts of radish seed extract, 0.7 part of magnesium stearate, 0.42 part of fruit glaze agent of compounding.
Processed according to the technique of embodiment 2, humidity is convenient value 50-65%, without individually control.
Comparative example 3
36 parts of lactose, 32 parts of oligosaccharide (wherein, 16 parts of FOS, 16 parts of xylo-oligosaccharide), 6 parts of mulberries extract, swallow
5 parts of wheat fiber, 5 parts of radish seed extract, 0.7 part of magnesium stearate, 0.4 part of fruit glaze agent of compounding.Compared with Example 1, lactose is used
Replace isomalt particle.
Processed according to the technique of embodiment 1.
Comparative example 4
36 parts of isomaltitol powder end, 32 parts of oligosaccharide (wherein, 16 parts of FOS, 16 parts of xylo-oligosaccharide), mulberries
6 parts of extract, 5 parts of common oats fibre, 5 parts of radish seed extract, 0.7 part of magnesium stearate, 0.4 part of fruit glaze agent of compounding.With embodiment 1
Compare, isomalt particle is replaced with isomaltitol powder end.
Processed according to the technique of embodiment 1.
Test example 2
Embodiment 1,2 and comparative example 1-4 are subjected to improvement constipation, adhesiveness, sticking, unilateral rough and compressibility effect
Experiment, it is specific as follows:
(1) effect of constipation is improved
According to the effect of embodiment 1, the technical scheme of the embodiment 2 checking present invention in terms of constipation is improved.
Tested using human experiment, select 60 volunteers, the age is 55-60 Sui, and constipation symptom is similar, random point
For three groups, two groups of subjects take the health products of the present invention daily during testing, and dosage is 4 tablet per days, 28d is taken altogether, separately
Outer one group is not taken health products, and the original Diet lifestyle of subject is not changed during three groups of subject's experiments.Observation index
It is as follows with test method:
Defecation condition is investigated, according to difficult defecation degree, can be divided into 1-4 grades, and 1 grade is that defecation is normal, and 2 grades drop to only have
Sense, sense of discomfort, 3 grades be bearing down, sense of discomfort substantially, or have just frequency but difficult defecation and amount is few, 4 grades are often stomachache or anus
Door burn feeling, influences defecation.1-4 grades are designated as 1-4 points respectively.
Fecal character is investigated:Fecal character is divided into 1-3 grades according to Bristol fecal character classification, 1 grade is as fragrant
Intestines or snake, it is smooth and soft;Soft agglomerate, but be easily drained;2 grades are sausage character but agglomerate, loose bulk, as mud
The excrement of shape;3 grades of hard groups for separation, as fruit stone, should not discharge.1-3 grades are designated as 1-3 points respectively.
Experimental result is as follows:
The defecation condition and faecal condition of each group of table 2
Group | Defecation frequency (times/week) | Defecation condition | Faecal condition |
Embodiment 1 | 6.25±0.60 | 1.45±0.21 | 1.24±0.17 |
Embodiment 2 | 6.12±0.45 | 1.56±0.18 | 1.28±0.20 |
Control group | 3.17±0.67 | 2.89±0.32 | 2.57±0.31 |
P values | < 0.01 | < 0.01 | < 0.01 |
The experimental data of table 2 shows that defecation frequency, defecation condition, faecal condition are respectively provided with statistical significance, take the present invention
Embodiment 1, after 2 products, obvious improvement is respectively provided with terms of defecation frequency, defecation condition and faecal condition, i.e., it is of the invention
Product can effectively improve constipation.
(2) effect of adhesiveness is improved
Technical scheme according to embodiment 1 and comparative example 1 has prepared pressed candy, and (tooth is bonded to adhesiveness
On sample amount) carry out sample analysis.
As a result show, the candy of embodiment 1 is without situation about sticking to one's teeth, and the candy of comparative example 1 is (i.e. fine in no addition oat
During dimension) situation about sticking to one's teeth is more more serious than embodiment 1.
(3) sticking, unilateral rough effect are improved.
The pressed candy that technical scheme according to embodiment 2 and comparative example 2 is prepared, to sticking, not only slide plate is carried out
Analysis.
The sticking effect detection of table 3 (1000)
Sample | Sample total tablet number | Not only slide plate number |
Embodiment 2 | 1000 | 2 |
Comparative example 2 | 1000 | 45 |
1000 pressed candies are manufactured according to embodiment 2 and comparative example 2 respectively, embodiment 2 controls of the present invention wet
After degree, not only slide plate quantity is 2;Comparative example 2 uses traditional humidity parameter, and not only slide plate quantity is 45.Obviously after control humidity
Candy tabletting sticking, rough situation can significantly be improved.
(4) effect of poor compressibility is improved
Technical scheme according to embodiment 1 and comparative example 3,4 has prepared pressed candy, and compressibility and hardness are carried out
Sample analysis.
The compressibility effect detection of table 4 (N=3)
Sample | Compressibility coefficient (%) | Hardness (kg/cm2) |
Embodiment 1 | 17±1.2 | 16.1±1.3 |
Comparative example 3 | 12±0.9 | 24.6±2.1 |
Comparative example 4 | 24±2.3 | 15.8±1.9 |
From the test data of table 4, the candy compressibility of embodiment 1 is good, and hardness is moderate;The candy of comparative example 3 can
Pressure property is good, but hardness is too high, and chewiness is poor;The candy poor compressibility of comparative example 4, weight differential is larger, and hardness is moderate.Can
See, that is, select granular isomalt to be obviously improved the compressibility and chewiness of candy.
Described above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (10)
1. a kind of health-care food composition, it is characterised in that be made up of mulberries extract and radish seed extract.
2. health-care food composition according to claim 1, it is characterised in that the mulberries extract and the radish seed
The mass ratio of extract is (5~15):(3~6).
3. health-care food composition as claimed in claim 1 or 2 is preparing the medicine for the treatment of person in middle and old age's constipation or is improving person in middle and old age
Application in the health products of constipation.
4. a kind of pressed candy, it is characterised in that including mulberries extract, radish seed extract, isomalt, oligomeric
Sugar, common oats fibre and magnesium stearate.
5. pressed candy according to claim 4, it is characterised in that in parts by weight, each component consumption is:Mulberries are extracted
5~15 parts of thing, 3~6 parts of radish seed extract, 25~40 parts of isomalt, 30~36 parts of oligosaccharide, common oats fibre 4~8
Part, 0.5~1.5 part of magnesium stearate.
6. the pressed candy according to claim 4 or 5, it is characterised in that the oligosaccharide is FOS and/or oligomeric
Xylose, the isomalt is isomalt particle.
7. the pressed candy according to any one of claim 4 to 6, it is characterised in that also including compounding fruit glaze agent.
8. the preparation method of pressed candy as any one of claim 4 to 7, it is characterised in that comprise the following steps:
Mulberries extract, radish seed extract, isomalt, oligosaccharide, common oats fibre and magnesium stearate are mixed, pressure
Piece, obtains pressed candy.
9. preparation method according to claim 8, it is characterised in that the humidity of the tabletting is 25%~45%.
10. preparation method according to claim 8 or claim 9, it is characterised in that the step of also including being coated after the tabletting.
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CN109985115A (en) * | 2019-05-23 | 2019-07-09 | 河南中医药大学 | A kind of Chinese medicine tea bag for treating constipation |
CN109985115B (en) * | 2019-05-23 | 2021-07-23 | 河南中医药大学 | Traditional Chinese medicine tea bag for treating constipation |
CN116602412A (en) * | 2023-06-02 | 2023-08-18 | 广东省农业科学院蚕业与农产品加工研究所 | Constipation-resistant composition, and preparation method and application thereof |
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