CN106943562A - Chinese medicine composition for treating cerebral apoplexy and preparation method thereof - Google Patents
Chinese medicine composition for treating cerebral apoplexy and preparation method thereof Download PDFInfo
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- CN106943562A CN106943562A CN201710219571.8A CN201710219571A CN106943562A CN 106943562 A CN106943562 A CN 106943562A CN 201710219571 A CN201710219571 A CN 201710219571A CN 106943562 A CN106943562 A CN 106943562A
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Abstract
The present invention provides a kind of for treating Chinese medicine composition of cerebral apoplexy and preparation method thereof, and the Chinese medicine composition is composed of the following components by mass percentage：Fructus alpiniae oxyphyllae 4%~6%, arillus longan 6%~8%, spina date seed 6%~8%, dried orange peel 3%~5%, the root of kudzu vine 6%~8%, purple perilla seed 3%~5%, peach kernel 13%~15%, nutmeg 4%~6%, gingko 6%~8%, Radix Angelicae Sinensis 13%~15%, hawthorn 6%~8%, field thistle 6%~8%, Longstamen Onion Bulb 4%~6%, rhizoma imperatae 6%~8%.Will above-mentioned component mix after add water be boiled into after paste with maltodextrin and potassium sorbate mixing granulation, dry, sterilizing,.The present invention complements each other promoting blood flow and remove blood stasis drug with tonic, and promoting blood circulation takes into account with tonifying Qi, and without wound just, tonifying Qi is not stopped up stagnant again, is closed and is used it for promoting blood circulation, then gas is prosperous, stagnation resolvation, network are logical；The various malaise symptoms of patient after early stage cerebral arterial thrombosis, treatment can be treated to have mitigated and cured.
Description
Technical field
The invention belongs to the Chinese medicine composition of integration of drinking and medicinal herbs category, and in particular to a kind of Chinese medicine group for being used to treat cerebral apoplexy
Compound and preparation method thereof.
Background technology
Cerebral apoplexy is also known as " apoplexy ", " cerebrovas-cularaccident ", is a kind of acute cerebrovascular diseases, is due to that cerebral vessels are unexpected
Rupture causes one group of disease of brain tissue impairment because angiemphraxis causes blood to cannot flow into brain.Cerebral apoplexy is to threaten people
The principal disease of class life and health, the incidence of disease is high, and the death rate is high, and disability rate is high, and high recurrence rate is that the great of current medical science is asked
Topic.The incidence of disease of Ischemic Stroke be higher than hemorrhagic apoplexy, cerebral apoplexy 60%~70% be ischemic, and the hemorrhagic death rate compared with
It is high.According to statistics, the patient of cerebral apoplexy occurs every year for China up to 2,000,000, and the incidence of disease is up to 1,20/,100,000, and disability rate is up to 75%,
Patients with cerebral apoplexy has different degrees of disability and can't take care of oneself, so preventing brain stroke and treatment early stroke
Important means as reduction Cerebral Haemorrhage Invasion Rate.
Cerebral arterial thrombosis belongs to motherland's medical science " apoplexy " category, and it occurs many and congenital examine and assigns not enough, and chronic dietary is unbalance,
Daily life it is inappropriate and ponder over bother excessively etc. factor it is relevant.《The correction of the errors of medical works》Record：" vigour was both empty, must can not reach stagnation of the blood pipe, blood vessel
Without gas, blood stasis must be stopped." therefore the deficiency of vital energy is the root cured the disease, blood stasis is core, and through disease all the time, qi deficiency to blood stasis is blood stasis
This sick pathomechanism.Congestion blood block brain network, brains, which lose, supports, and can cause all-around exercises and sensory disturbance, forgetful, speech occurs
Fill in the symptoms such as strong tongue, hemiplegia, apathy.Therefore, qi deficiency to blood stasis is the most common card type of cerebral arterial thrombosis.Each traditional Chinese medicines
The medicine that research and development prevent and treat cerebrovascular disease is considered as by thing scholar and Medical Technologist and each side's strength (government, public organization) urgently to be made
Life, but preferable medicine is there is no both at home and abroad.In preventing brain stroke and treatment early stroke, using the Chinese medicine activated blood circulation and dispersed blood clots
Have more preferable effect.
The content of the invention
It is an object of the invention to provide a kind of Chinese medicine composition for treating cerebral apoplexy, using the treatment means of solid decoction of medicinal ingredients,
For treating early stage cerebral arterial thrombosis, therapeutic effect is good, can long-term taking, with having no toxic side effect.
The technical solution adopted in the present invention is,
Chinese medicine composition for treating cerebral apoplexy, it is by mass percentage, raw materials used composed of the following components：
Fructus alpiniae oxyphyllae 4%~6%, arillus longan 6%~8%, spina date seed 6%~8%, dried orange peel 3%~5%, the root of kudzu vine 6%~
8%th, purple perilla seed 3%~5%, peach kernel 13%~15%, nutmeg 4%~6%, gingko 6%~8%, Radix Angelicae Sinensis 13%~15%,
Hawthorn 6%~8%, field thistle 6%~8%, Longstamen Onion Bulb 4%~6%, rhizoma imperatae 6%~8%, the mass percent of above each component
Summation is 100%.
The above-mentioned preparation method for being used to treat cerebral apoplexy Chinese medicine composition, including following operating procedure：
Step 1,
By mass percentage, fructus alpiniae oxyphyllae 4%~6%, arillus longan 6%~8%, spina date seed 6%~8%, dried orange peel 3% are weighed
~5%, the root of kudzu vine 6%~8%, purple perilla seed 3%~5%, peach kernel 13%~15%, nutmeg 4%~6%, gingko 6%~8%,
Radix Angelicae Sinensis 13%~15%, hawthorn 6%~8%, field thistle 6%~8%, Longstamen Onion Bulb 4%~6%, rhizoma imperatae 6%~8%, above each group
The mass percent summation of part is 100%；
Step 2,
14 taste raw materials in step 1 are added water to cook twice, the water of first time plus 10 times of amounts are decocted 2 hours, are added for the second time
The water of 6 times of amounts, is decocted 2 hours, merges decocting liquid twice, filtering, it is 1.20~1.40 (60 DEG C) that filtrate, which is concentrated into relative density,
Thick paste；
Step 3,
Separately maltodextrin and potassium sorbate are taken, and maltodextrin and potassium sorbate were crushed into 80 mesh, it is standby；
Step 4,
By mass percentage, thick paste 24%~26.97%, the and of maltodextrin 73%~75.97% that step 1 is obtained are weighed
Potassium sorbate 0.01%~0.03%, the mass percent summation of above each component is 100%；Thick paste and water are stirred
To whitewashing, the weight ratio of thick paste and water is 1:2；
Step 5,
In multifunctional fluidized bed, maltodextrin and potassium sorbate are subjected to material heating and premixed, mixed material is obtained, so
Pelletized afterwards toward whitewashing on mixed material, finally dry, cool, discharging, shutdown；
Step 6,
Last whole grain and filling, is produced.
In above-mentioned steps 5, by maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is set to 15m3/ h~
25m3/ h, EAT is set to 80 DEG C~100 DEG C, heating premix is carried out to material 7~15 minutes, obtains mixed material；In advance
It is mixed finish after, by adjusting air quantity and EAT so that mixed material temperature reaches 35 DEG C~40 DEG C, then multi-functional fluidisation
Bed starts whitewashing, and spouting velocity is set to 15rpm~20rpm, and atomizing pressure is 1.50bar~2.0bar, due to thing after whitewashing
Material is aggravated, temperature reduction, and air quantity is adjusted at any time and keeps material fully to jump, and regulation EAT keeps temperature of charge at any time
At 35 DEG C~40 DEG C, whitewashing is closed after whitewashing 15min~30min, granulation is completed；Multifunctional fluidized bed EAT is set again
It is set to 100 DEG C material is dried, regulation air quantity keeps material fully to jump, when the moisture≤2.0% of material, by air intake
Temperature is down to 25 DEG C~45 DEG C, the temperature of material is reduced to 25 DEG C~45 DEG C, finally discharging shutdown.
In above-mentioned steps 6, the particle that the dry particl that step 5 is obtained is chosen on shaking screen between the mesh of 14 mesh~60 is completed
The dry particl of selection, is then fitted into bag and completes filling by whole grain.
The beneficial effects of the invention are as follows：Promoting blood flow and remove blood stasis drug complements each other with tonic, promoting blood circulation taken into account with tonifying Qi, invigorate blood circulation without
Wound just, do not stop up stagnant again, closes and uses it by tonifying Qi, then gas is prosperous, stagnation resolvation, network are logical；Early stage cerebral arterial thrombosis can be treated, future trouble is treated
The various malaise symptoms of person have mitigated and cured, and can also be used as the medicine of preventing brain stroke；The property of medicine is gentle, can take for a long time
With being had no toxic side effect to body.
Embodiment
The present invention provides a kind of Chinese medicine composition for being used to treat cerebral apoplexy, composed of the following components by mass percentage：
Fructus alpiniae oxyphyllae 4%~6%, arillus longan 6%~8%, spina date seed 6%~8%, dried orange peel 3%~5%, the root of kudzu vine 6%~
8%th, purple perilla seed 3%~5%, peach kernel 13%~15%, nutmeg 4%~6%, gingko 6%~8%, Radix Angelicae Sinensis 13%~15%,
Hawthorn 6%~8%, field thistle 6%~8%, Longstamen Onion Bulb 4%~6%, rhizoma imperatae 6%~8%, the mass percent of above each component
Summation is 100%.
The pharmacological action of Chinese medicine of the present invention is as follows：
Fructus alpiniae oxyphyllae：Warming up astringent sperm contracting urine, it is warming spleen and stopping diarrha to take the photograph saliva, for enuresis with renal asthenia, frequent urination, pass out semen gonorrhoea, malaria
The many salivas of crymodynia mouthful in diarrhea, abdomen.
Arillus longan：It is sweet, temperature, thoughts of returning home the spleen channel tonifying heart and spleen, nourishing blood and tranquilization；For insufficiency of vital energy and blood, palpitaition is seized with terror secondary, forgetful to lose
Sleep, blood deficiency chlorosis.
Spina date seed：Nourishing heart tonifying liver, antitoxic heart-soothing and sedative, arrest sweating promotes the production of body fluid, for restlessness of asrhenia type and insomnia, horrified to much dream, body void hidrosis, Tianjin
Wound is thirsty.
Dried orange peel：Regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm；For abdominal fullness and distention, deficiency of food is vomited and diarrhoea, coughing with a lot of sputum.
The root of kudzu vine：Puerarin in the root of kudzu vine has good protection blood vessel endothelium, and the effect of blood vessel endothelium injury is repaired in regulation.
Purple perilla seed：Relieving exterior syndrome and dispelling cold, relieving QI stagnancy in the stomach, for anemofrigid cold, cough evil of vomitting, the vomiting of pregnancy, fish and crab poisoning sending down abnormally ascending
Resolving sputum, only phlegm relieving asthma, relax bowel, for phlegm stops up the circulation of vital energy in the wrong direction, cough and asthma, dry constipation of intestines.
Peach kernel：Promoting blood circulation, relaxes bowel, relieving cough and asthma, for amenorrhoea dysmenorrhoea, lung carbuncle acute appendicitis, injury from falling down, and intestinal dryness is just
It is secret, cough and asthma.
Nutmeg：It is pungent, temperature, returns spleen stomach large intestine channel middle benefit gas promoting the circulation of qi, relieving diarrhea with astringents, for deficiency-cold in spleen and stomach, endless diarrhea, gastral cavity abdomen
Distending pain, deficiency of food vomiting.
Gingko：It is sweet, it is bitter, it is puckery, put down, poisonous, return lung kidney channel astringing lung for relieving asthma, stop-band contracting urine is breathed with cough for abundant expectoration, with lower white
It is turbid, enuresis frequent micturition.
Radix Angelicae Sinensis：Replenishing and activating blood, menstruction regulating and pain relieving, moistening dryness for relaxing bowels, for blood deficiency chlorosis, dizziness palpitaition, irregular menstruation, dysmenorrhoea is closed
Through asthenia cold abdominalgia, arthralgia pain due to rheumatism, injury from falling down, ulcer sore wound, dry constipation of intestines；And there is facilitation to angiogenesis.
Hawthorn：The sweet tepor returns spleen stomach Liver Channel food digesting stomach fortifying of acid, scattered stasis changes turbid lipid-loweringing.For meat stagnation, gastral cavilty is swollen
It is full, diarrhea dysentery abdominal pain, extravasated blood Amenorrhea, postpartum stasis, confidant sting, chest impediment and cardialgia, hernia pain, hyperlipidemia.
Field thistle：Sweet, bitter cool, the thoughts of returning home, Liver Channel cooling blood and hemostasis dissipates stasis of blood removing toxicity for eliminating carbuncles.For spitting blood, hematuria, wound of having blood in stool goes out
Blood, carbuncle sore tumefacting virus.
Longstamen Onion Bulb：Activate yang and remove abstruction, promoting the circulation of qi causes, for chest impediment and cardialgia, epigastric abdominal fullness distending pain, weight after rush down dysentery.
Rhizoma imperatae：Cooling blood and hemostasis, reducing fever and causing diuresis is spitted blood for blood-head, hematuria, pyreticosis polydipsia, jaundice with damp-heat pathogen, oedema urine
It is few, puckery pain of heat gonorrhea.
Cerebrovas-cularaccident and apoplexy sequelae, mostly because of healthy tendency virtual loss, blood stagnancy due to deficiency of QI, train of thought silt resistance, tendon and vessel muscle lose and supported
It is caused.Control suitable tonifying Qi row stagnant, it is promoting blood circulation and removing obstruction in channels.According to《Chinese Pharmacopoeia》, Radix Angelicae Sinensis is reused in side, it is promoting blood circulation and removing obstruction in channels without blood trouble, it is monarch
Medicine.Arillus longan tonifying Qi, the prosperous then blood of gas, the stasis of blood goes network to lead to, and is minister.Peach kernel, hawthorn, Longstamen Onion Bulb, gingko, the root of kudzu vine, dredging collateral promoting blood circulation and removing blood stasis；
Spina date seed, field thistle, rhizoma imperatae, blood-nourishing benefit are cloudy；Dried orange peel, purple perilla seed, nutmeg, fructus alpiniae oxyphyllae, warm-natured and regulating qi-flowing for activating stagnancy, make gas row then
Blood；Peach kernel, hawthorn, Longstamen Onion Bulb, gingko, the root of kudzu vine, spina date seed, field thistle, rhizoma imperatae, dried orange peel, purple perilla seed, nutmeg, fructus alpiniae oxyphyllae, with
On be adjutant.Full side's promoting blood circulation is taken into account with tonifying Qi, and without wound just, tonifying Qi is not stopped up stagnant again, is closed and is used it for promoting blood circulation, then gas is prosperous, stagnation resolvation,
Network leads to, to reach the purpose of rehabilitation cerebrovascular disease.
Chinese medicine composition of the present invention is by the way of oral, oral 10 grams every time, 2 times a day, is within one month a course for the treatment of.
With reference to specific embodiment, the present invention is described in detail.
Embodiment 1
Preparation method for treating cerebral apoplexy Chinese medicine composition, including following operating procedure：
Step 1,
Weigh fructus alpiniae oxyphyllae 6kg, arillus longan 6kg, spina date seed 7kg, dried orange peel 4kg, root of kudzu vine 6kg, purple perilla seed 3kg, peach kernel 15kg,
Nutmeg 5kg, gingko 6kg, Radix Angelicae Sinensis 15kg, hawthorn 7kg, field thistle 6kg, Longstamen Onion Bulb 6kg, rhizoma imperatae 8kg；
Step 2,
14 taste raw materials in step 1 are added water to cook twice, the water of first time plus 10 times of amounts are decocted 2 hours, are added for the second time
The water of 6 times of amounts, is decocted 2 hours, merges decocting liquid twice, filtering, and filtrate is concentrated into the thick paste that relative density is 1.35 (60 DEG C)；
Step 3,
Separately maltodextrin and potassium sorbate are taken, and maltodextrin and potassium sorbate were crushed into 80 mesh, it is standby；
Step 4,
Weigh thick paste 20.5kg, maltodextrin 61.5kg and potassium sorbate 20g；Thick paste and water are uniformly mixing to obtain spray
The weight ratio of slurry, thick paste and water is 1:2；
Step 5,
By maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is set to 20m3/ h, EAT is set
For 90 DEG C, heating premix is carried out to material 10 minutes, obtain mixed material；After premix is finished, by adjusting air quantity and entering wind-warm syndrome
Degree so that mixed material temperature reaches 36 DEG C, then multifunctional fluidized bed to start whitewashing, spouting velocity is set to 17rpm, is atomized
Pressure is 1.70bar, because material is aggravated after whitewashing, temperature reduction, and air quantity is adjusted at any time and keeps material fully to jump, and at any time
Regulation EAT makes temperature of charge close whitewashing after being maintained at 36 DEG C, whitewashing 20min, completes granulation；Again by multi-functional fluidisation
The EAT of bed is set to 100 DEG C material is dried, and regulation air quantity keeps material fully to jump, when material moisture≤
When 2.0%, EAT is down to 25 DEG C, the temperature of material is reduced to 25 DEG C, finally discharging shutdown；
Step 6,
The particle that the dry particl that step 5 is obtained is chosen on shaking screen between the mesh of 14 mesh~60 completes whole grain, then will
The dry particl of selection, which is fitted into bag, completes filling.
Embodiment 2
Preparation method for treating cerebral apoplexy Chinese medicine composition, including following operating procedure：
Step 1,
Weigh fructus alpiniae oxyphyllae 4kg, arillus longan 7kg, spina date seed 6kg, dried orange peel 4kg, root of kudzu vine 8kg, purple perilla seed 5kg, peach kernel 13kg,
Nutmeg 6kg, gingko 7kg, Radix Angelicae Sinensis 13kg, hawthorn 8kg, field thistle 8kg, Longstamen Onion Bulb 5kg, rhizoma imperatae 6kg；
Step 2,
14 taste raw materials in step 1 are added water to cook twice, the water of first time plus 10 times of amounts are decocted 2 hours, are added for the second time
The water of 6 times of amounts, is decocted 2 hours, merges decocting liquid twice, filtering, and filtrate is concentrated into the thick paste that relative density is 1.20 (60 DEG C)；
Step 3,
Separately maltodextrin and potassium sorbate are taken, and maltodextrin and potassium sorbate were crushed into 80 mesh, it is standby；
Step 4,
Weigh thick paste 24kg, maltodextrin 75.97kg and potassium sorbate 30g；Thick paste and water are uniformly mixing to obtain whitewashing,
The weight ratio of thick paste and water is 1:2；
Step 5,
By maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is set to 25m3/ h, EAT is set
For 80 DEG C, heating premix is carried out to material 7 minutes, obtain mixed material；After premix is finished, by adjusting air quantity and entering wind-warm syndrome
Degree so that mixed material temperature reaches 40 DEG C, then multifunctional fluidized bed to start whitewashing, spouting velocity is set to 15rpm, is atomized
Pressure is 1.50bar, because material is aggravated after whitewashing, temperature reduction, and air quantity is adjusted at any time and keeps material fully to jump, and at any time
Regulation EAT makes temperature of charge close whitewashing after being maintained at 40 DEG C, whitewashing 15min, completes granulation；Again by multi-functional fluidisation
The EAT of bed is set to 100 DEG C material is dried, and regulation air quantity keeps material fully to jump, when material moisture≤
When 2.0%, EAT is down to 35 DEG C, the temperature of material is reduced to 35 DEG C, finally discharging shutdown；
Step 6,
The particle that the dry particl that step 5 is obtained is chosen on shaking screen between the mesh of 14 mesh~60 completes whole grain, then will
The dry particl of selection, which is fitted into bag, completes filling.
Embodiment 3
Preparation method for treating cerebral apoplexy Chinese medicine composition, including following operating procedure：
Step 1,
Weigh fructus alpiniae oxyphyllae 4kg, arillus longan 8kg, spina date seed 8kg, dried orange peel 3kg, root of kudzu vine 7kg, purple perilla seed 4kg, peach kernel 14kg,
Nutmeg 4kg, gingko 8kg, Radix Angelicae Sinensis 14kg, hawthorn 7kg, field thistle 7kg, Longstamen Onion Bulb 5kg, rhizoma imperatae 7kg；
Step 2,
14 taste raw materials in step 1 are added water to cook twice, the water of first time plus 10 times of amounts are decocted 2 hours, are added for the second time
The water of 6 times of amounts, is decocted 2 hours, merges decocting liquid twice, filtering, and filtrate is concentrated into the thick paste that relative density is 1.30 (60 DEG C)；
Step 3,
Separately maltodextrin and potassium sorbate are taken, and maltodextrin and potassium sorbate were crushed into 80 mesh, it is standby；
Step 4,
Weigh thick paste 26.97kg, maltodextrin 73kg and potassium sorbate 30g；Thick paste and water are uniformly mixing to obtain whitewashing,
The weight ratio of thick paste and water is 1:2；
Step 5,
By maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is set to 15m3/ h, EAT is set
For 100 DEG C, heating premix is carried out to material 12 minutes, obtain mixed material；After premix is finished, by adjusting air quantity and entering wind-warm syndrome
Degree so that when mixed material temperature reaches 38 DEG C, then multifunctional fluidized bed to start whitewashing, spouting velocity is set to 18rpm, mist
Change pressure is 2.0bar, because material is aggravated after whitewashing, temperature reduction, and air quantity is adjusted at any time and keeps material fully to jump, and with
When regulation EAT temperature of charge is maintained at 38 DEG C, close whitewashing after whitewashing 30min, complete granulation；Again by multi-functional stream
The EAT of change bed is set to 100 DEG C and material is dried, and regulation air quantity keeps material fully to jump, when the moisture of material
When≤2.0%, EAT is down to 30 DEG C, the temperature of material is reduced to 30 DEG C, finally discharging shutdown；
Step 6,
The particle that the dry particl that step 5 is obtained is chosen on shaking screen between the mesh of 14 mesh~60 completes whole grain, then will
The dry particl of selection, which is fitted into bag, completes filling.
Embodiment 4
Preparation method for treating cerebral apoplexy Chinese medicine composition, including following operating procedure：
Step 1,
Weigh fructus alpiniae oxyphyllae 5kg, arillus longan 7kg, spina date seed 7kg, dried orange peel 5kg, root of kudzu vine 6kg, purple perilla seed 5kg, peach kernel 15kg,
Nutmeg 6kg, gingko 8kg, Radix Angelicae Sinensis 13kg, hawthorn 6kg, field thistle 6kg, Longstamen Onion Bulb 4kg, rhizoma imperatae 7kg；
Step 2,
14 taste raw materials in step 1 are added water to cook twice, the water of first time plus 10 times of amounts are decocted 2 hours, are added for the second time
The water of 6 times of amounts, is decocted 2 hours, merges decocting liquid twice, filtering, and filtrate is concentrated into the thick paste that relative density is 1.40 (60 DEG C)；
Step 3,
Separately maltodextrin and potassium sorbate are taken, and maltodextrin and potassium sorbate were crushed into 80 mesh, it is standby；
Step 4,
Weigh thick paste 24.02kg, maltodextrin 75.97kg and potassium sorbate 10g；Thick paste and water are uniformly mixing to obtain spray
The weight ratio of slurry, thick paste and water is 1:2；
Step 5,
By maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is set to 20m3/ h, EAT is set
For 95 DEG C, heating premix is carried out to material 15 minutes, obtain mixed material；After premix is finished, by adjusting air quantity and entering wind-warm syndrome
Degree so that mixed material temperature reaches 35 DEG C, then multifunctional fluidized bed to start whitewashing, spouting velocity is set to 20rpm, is atomized
Pressure is 1.70bar, because material is aggravated after whitewashing, temperature reduction, and air quantity is adjusted at any time and keeps material fully to jump, and at any time
Regulation EAT makes temperature of charge close whitewashing after being maintained at 35 DEG C, whitewashing 25min, completes granulation；Again by multi-functional fluidisation
The EAT of bed is set to 100 DEG C material is dried, and regulation air quantity keeps material fully to jump, when material moisture≤
When 2.0%, EAT is down to 45 DEG C, the temperature of material is reduced to 45 DEG C, finally discharging shutdown；
Step 6,
The particle that the dry particl that step 5 is obtained is chosen on shaking screen between the mesh of 14 mesh~60 completes whole grain, then will
The dry particl of selection, which is fitted into bag, completes filling.
Clinical data：
1st, case selection：
In order to verify the effect of medicine of the present invention, in December, -2015 in June, 2014, the early stage ischemic brain made a definite diagnosis is selected
25 clinical observations of apoplexy patient, wherein male 12, women 13, age 45-68 Sui, average age 58 years old；
2nd, medicament selection：
Patient takes medicine of the present invention, and 2 times a day, each 10g, warm water delivery service in half an hour after meal, is within 30 days a treatment
Journey, continuously takes 2 to 4 courses for the treatment of, and the person of being in a bad way follows the doctor's advice increase at discretion consumption.
While Chinese medicine of the present invention is taken, there is the patient of history of hypertension, to adhere to Treatment of Hypertension, there is diabetes medical history
Patient, will adhere to glucose-lowering treatment, and the patient for having high fat of blood will adhere to lipid-lowering therapy；And often do simple motion during taking medicine,
And diet is light, greasy thing not being eaten, is not drunk, non-smoking eats fruits and vegetables more.
3rd, efficacy determination：
The symptom of table 1, the change of sign
As can be seen from Table 1, patient is taken after medicine of the present invention, dizziness, headache, side extremity numbness, limb adynamia or
Activity it is ineffective, turn dark before one's eyes, blurring of vision, the of short duration loss of consciousness, fluctuation of blood pressure, drowsiness, dysphonia, the symptom pronounced indistinctly
All make moderate progress；
(2) its result is as follows to be detected to the lectin from hemolymph inspection before Case treatment and after treatment：
The comparison of the lectin from hemolymph index of table 2
Change from table 2 it can be seen that high shear, undercut change and platelet aggregation rate of the Chinese medicine of the present invention to whole blood viscosity have
Kind effect, so as to effectively prevent the formation of cerebral thrombus.
Case 1
The Mr. Wang, male in Xianyang, Shanxi province city, 66 years old, hypertension 15 years；Existing disease：Patient often have one side, tongue, lip or/
With the sensation of extremity numbness, also day rotation ground can be felt suddenly sometimes with tinnitus, dysacousis or regarding thing sense of rotation sometimes
Turn, rock indefinite, astasia；CT examination：The ﹪ of both sides internal carotid artery stenosis≤70, to blood supply insufficiency of brain；It is diagnosed as：In early days
Mild cerebral ischemic cerebral apoplexy；Take Chinese medicine of the present invention, daily two doses (one 10g), while enjoining the patient to take Chinese medicine of the present invention,
Adhere to Treatment of Hypertension, and often do during taking medicine simple motion, and diet is light, eats fruits and vegetables more；Take the present invention
After 3 courses for the treatment of of Chinese medicine, symptom gradually takes a turn for the better, and continues to take 2 courses for the treatment of, symptom disappears substantially, can be with normal life.
Case 2
The Chen in Xi'an City, Shanxi Province Hu County, female, 58 years old；There is dizziness, nearly two months, the frequent head of patient the year before in patient
It is confused dizzy, or even faint on ground, unexpected dark and dim eyesight, blurring of vision, but often can voluntarily recover after the several seconds；Patient comes me
Place is medical, and being diagnosed as carotid artery system ischemic causes cerebral blood flow to reduce, and then causes foveal region of retina artery or branch to be drawn
Play occlusion.Enjoin patient to take Chinese medicine of the present invention, and often do during taking medicine simple motion, and diet is light, eats fruit more
And vegetables；Patient is taken after Chinese medicine of the present invention, daily two doses (one 10g), 3 courses for the treatment of, and symptom gradually takes a turn for the better, and continues to take 3
After individual month, patient symptom disappears, can normal life.
Case 3
Lee of Shaanxi Province Weinan City Fuping County, 64 years old, man；Patient started before one month occur it is One's spirits are drooping depressed, always
Sleepy is felt or had dizzy spells all day, is frequently yawned, is shunk into oneself in the recent period, apathy is slow in action, some appearance are short
The temporary loss of consciousness；Being diagnosed as vertebral artery insufficiency causes brain tissue ischemia anoxic；Take after this formula daily two doses it is (one
10g), after 2 courses for the treatment of, malaise symptoms substantially mitigate, and continue to take 1 month, and symptom disappears, can be with normal life.
Case 4
Shaanxi Province's Yulin City it is tall certain, 62 years old, man had diabetic history；Occur within nearly 2 months that side limbs are weak, strength subtracts
It is weak, insubjection, weak fingers, article drops suddenly in hand, and a pin mops floor when on foot.The examination in hospital is gone to be：The cerebrovascular is supplied
Blood deficiency causes motor neuron dysfunction.Chinese medicine of the present invention is taken, daily two doses (one 10g) enjoins patient to take this hair
While bright Chinese medicine, glucose-lowering treatment is adhered to, and often do during taking medicine simple motion, and diet is light, eats fruit and vegetable more
Dish；Take after 4 courses for the treatment of of medicine of the present invention, can normally walk, life can take care of oneself, and can do simple housework；Refer to nose, palm wheel
It can complete, but act slower for action, heel-knee-tibia test.
Claims (4)
1. the Chinese medicine composition for treating cerebral apoplexy, it is characterised in that by mass percentage, raw materials used by following components group
Into：
Fructus alpiniae oxyphyllae 4%~6%, arillus longan 6%~8%, spina date seed 6%~8%, dried orange peel 3%~5%, the root of kudzu vine 6%~8%, purple
Perillaseed 3%~5%, peach kernel 13%~15%, nutmeg 4%~6%, gingko 6%~8%, Radix Angelicae Sinensis 13%~15%, hawthorn
6%~8%, field thistle 6%~8%, Longstamen Onion Bulb 4%~6%, rhizoma imperatae 6%~8%, the mass percent summation of above each component
For 100%.
2. it is used for the preparation method for treating cerebral apoplexy Chinese medicine composition described in a kind of claim 1, it is characterised in that including following
Operating procedure：
Step 1,
By mass percentage, weigh fructus alpiniae oxyphyllae 4%~6%, arillus longan 6%~8%, spina date seed 6%~8%, dried orange peel 3%~
5%th, the root of kudzu vine 6%~8%, purple perilla seed 3%~5%, peach kernel 13%~15%, nutmeg 4%~6%, gingko 6%~8%, when
Return 13%~15%, hawthorn 6%~8%, field thistle 6%~8%, Longstamen Onion Bulb 4%~6%, rhizoma imperatae 6%~8%, above each component
Mass percent summation be 100%；
Step 2,
14 taste raw materials in step 1 are added water to cook twice, the water of 10 times of amounts are added for the first time, are decocted 2 hours, second plus 6 times
The water of amount, is decocted 2 hours, merges decocting liquid twice, filtering, it is the thick of 1.20~1.40 (60 DEG C) that filtrate, which is concentrated into relative density,
Cream；
Step 3,
Separately maltodextrin and potassium sorbate are taken, and maltodextrin and potassium sorbate were crushed into 80 mesh, it is standby；
Step 4,
By mass percentage, thick paste 24%~26.97%, maltodextrin 73%~75.97% and sorb that step 1 is obtained are weighed
Sour potassium 0.01%~0.03%, the mass percent summation of above each component is 100%；Thick paste and water are uniformly mixing to obtain spray
The weight ratio of slurry, thick paste and water is 1:2；
Step 5,
In multifunctional fluidized bed, maltodextrin and potassium sorbate are subjected to material heating and premixed, mixed material is obtained, it is then past
Whitewashing is pelletized on mixed material, is finally dried, cools, discharges, is shut down；
Step 6,
Last whole grain and filling, is produced.
3. it is used for the preparation method for treating cerebral apoplexy Chinese medicine composition according to claim 2, it is characterised in that：The step
In 5, by maltodextrin and potassium sorbate be placed in it is multifunctional fluidized bed in, air quantity is set to 15m3/ h~25m3/ h, EAT is set
80 DEG C~100 DEG C are set to, heating premix is carried out to material 7~15 minutes, mixed material is obtained；After premix is finished, pass through regulation
Air quantity and EAT so that mixed material temperature reaches 35 DEG C~40 DEG C, it is then multifunctional fluidized bed to start whitewashing, whitewashing speed
Degree is set to 15rpm~20rpm, and atomizing pressure is 1.50bar~2.0bar, because material is aggravated after whitewashing, temperature reduction, with
When regulation air quantity keep material fully to jump, and regulation EAT makes temperature of charge be maintained at 35 DEG C~40 DEG C at any time, whitewashing
Whitewashing is closed after 15min~30min, granulation is completed；Multifunctional fluidized bed EAT is set into 100 DEG C again to enter material
Row drying, regulation air quantity keeps material fully to jump, and when the moisture≤2.0% of material, EAT is down into 25 DEG C~45
DEG C, the temperature of material is reduced to 25 DEG C~45 DEG C, finally discharging shutdown.
4. it is used for the preparation method for treating cerebral apoplexy Chinese medicine composition according to claim 2, it is characterised in that：The step
In 6, the particle that the dry particl that step 5 is obtained is chosen on shaking screen between the mesh of 14 mesh~60 completes whole grain, then will choose
Dry particl be fitted into bag and complete filling.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116983368A (en) * | 2023-08-17 | 2023-11-03 | 广州新征程生物科技有限公司 | Traditional Chinese medicine for treating apoplexy sequela and preparation method thereof |
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| CN106474418A (en) * | 2016-12-28 | 2017-03-08 | 陕西红顶名医堂药业有限公司 | For treating Chinese medicine composition of gastropathy and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106474418A (en) * | 2016-12-28 | 2017-03-08 | 陕西红顶名医堂药业有限公司 | For treating Chinese medicine composition of gastropathy and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN116983368A (en) * | 2023-08-17 | 2023-11-03 | 广州新征程生物科技有限公司 | Traditional Chinese medicine for treating apoplexy sequela and preparation method thereof |
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