CN106943457A - A kind of preparation method of ozone oil lipstick - Google Patents

A kind of preparation method of ozone oil lipstick Download PDF

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Publication number
CN106943457A
CN106943457A CN201710221331.1A CN201710221331A CN106943457A CN 106943457 A CN106943457 A CN 106943457A CN 201710221331 A CN201710221331 A CN 201710221331A CN 106943457 A CN106943457 A CN 106943457A
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China
Prior art keywords
ozone
oil
olive oil
container
olive
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Pending
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CN201710221331.1A
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Chinese (zh)
Inventor
侯桂英
焦雨薇
王庆利
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FIFTH HOSPITAL OF SHIJIAZHUANG
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FIFTH HOSPITAL OF SHIJIAZHUANG
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Priority to CN201710221331.1A priority Critical patent/CN106943457A/en
Publication of CN106943457A publication Critical patent/CN106943457A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/35Extraction with lipophilic solvents, e.g. Hexane or petrol ether

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Cosmetics (AREA)

Abstract

The present invention relates to a kind of preparation method that olive oil is prepared into the ozone oil lipstick containing ozone.The present invention can produce the stable ozone lipstick of ozone content, product is without any toxicity and side effects, the resistance to the action of a drug without antibiotic sample, have no drug resistance, it is nonirritant, no mutagenicity, treatment and the beauty of skin available for disease of skin, product has good bactericidal effect, this method has saving fund, simple and reliable, the advantages of pollution-free.

Description

A kind of preparation method of ozone oil lipstick
Technical field
The present invention relates to field of medicaments, and in particular to a kind of preparation method of ozone oil lipstick.
Background technology
In medical domain, ozone has good bactericidal effect, induction and the effect of regulation immunologic mechanism and without pair because of it Effect, safe noresidue, have widely in a variety of diseases such as treatment skin disease, acne, bedsore, various organ inflammations Using.But ozone gas is extremely unstable in itself, it is very easy to resolve into common oxygen, therefore, it is difficult to store and transport.So that occupying Family patient is very inconvenient using ozone therapy, and the appearance part of liquid ozone carburetion solves this problem, ozone oil antiseptic There are wide spectrum, strength antibacterial action, its active ingredient is trioxide, the elemental oxygen discharged again when using, with powerful Oxidation disinfection disinfecting power, so that eliminating pathogen, inactivation of viruses, control inflammation.Meanwhile, the catabolite of ozone oil antiseptic For oxygen, lesions position blood circulation can be promoted, cell bio-activity is improved, strengthen metabolism, accelerating wound healing is carried High immunity.Such product have it is nontoxic, have no side effect, the resistance to the action of a drug of no antibiotic sample, have no drug resistance, nonirritant, no cause Mutability, it is safe as food.When temperature is less than 15 DEG C, ozone carburetion can preserve ozone wherein more than 10 years, But when temperature is more than 25 DEG C, ozone can then be discharged from ozone oil, using effect is reduced.Fluid preservation and make simultaneously It is practical with convenient solid is all not so good as, therefore ozone oil antiseptic is prepared into wieldy ozone oil lipstick, it is relatively good Selection.
The content of the invention
In order to solve the shortcomings and deficiencies of prior art, the present invention proposes a kind of preparation method of ozone oil lipstick, and it is tied Structure is simple, easy to use.
The technical scheme is as follows:
A kind of preparation method of ozone oil lipstick, it is characterised in that comprise the technical steps that:
(1) container is set, edible virgin oil is injected in container;
(2) an ozone instrument is set, the oxygen output pipe of ozone instrument is extend into below the edible virgin oil liquid level in container;
(3) ozone instrument is opened, so that ozone constantly pours high-concentrated ozone by oxygen output pipe into edible virgin oil, The high-concentrated ozone is set to be sufficiently mixed with edible virgin oil, ozone olive oil is fabricated to, this process is about needed 2-3 days, directly To olive oil lighter for it is sticky it is yellowish untill;
(4) the ozone olive oil is transferred to sealing container, the sealing container is inserted into refrigerating chamber refrigeration, refrigerated storage temperature For 0 DEG C -5 DEG C, solidify the ozone olive oil, it is stand-by;
(5) inserted after smashing caulis lonicerae, Radix Angelicae Sinensis to pieces in sesame oil, immersion 1-5 hours after, small fire be warming up to 100 DEG C decoct to 10-20 minutes, it is cooled within 100 DEG C, adds Asian puccoon, stirring continues small fire and decocted, cooling withered to medicine, and remove slag trapped fuel, then Add the borneol stirring pulverized to melt, be fabricated to Groomwell root oil, stand-by, the caulis lonicerae, Radix Angelicae Sinensis, Asian puccoon, borneol, sesame oil quality Than for 5:2.5:5:1:70;
(6) Groomwell root oil that beeswax, olive oil and step (5) are made is put into vessel in heating, the beeswax, olive oil with The mass ratio of the Groomwell root oil is 2:2:1, heat while stirring, while vitamin E, vitamin B6 are added, the beeswax and dimension Raw element E, vitamin B6 mass ratio are 20:1:0.1-0.2, heating-up temperature is 60 DEG C, until the beeswax is all molten into liquid, It is sufficiently mixed with olive oil, then adds the ozone olive oil being made in step (4), the beeswax quality and ozone olive oil ratio For 1:2-3, will the ozone olive oil add container after continue stir, heating until fusing, all turn into after liquid will mix In liquid injected plastic lipstick tube;
(7) the canned ozone oil lipstick is put into refrigerator cooled and solidified, temperature is 0 DEG C -5 DEG C.
As a kind of preferred scheme, the container sets muffler to be connected to ozone instrument air inlet, makes from surplus in container Residual air body is discharged into ozone instrument formation sealing and circulating loop, prevents ozone leakage.
The present invention has saving fund, pollution-free, the high advantage of the ozone oil lipstick stability produced, and using just Victory, outwards back-outs lipstick rotation on smearing skin when using.Clinical practice:Treat exfoliative cheilitis, bicker inflammation, mouth The bacterium such as chamber ulcer and burn, diabetes, fungus-caused skin chronic inflammation, can treat a variety of diseases.
Brief description of the drawings
Technical scheme in order to illustrate more clearly the embodiments of the present invention, below will be to that will make needed for embodiment description Accompanying drawing is briefly described, it should be apparent that, drawings in the following description are only some embodiments of the present invention, for For those of ordinary skill in the art, on the premise of not paying creative work, other can also be obtained according to these accompanying drawings Accompanying drawing.
Fig. 1 is the schematic diagram for the embodiment that the present invention prepares ozone oil.
In figure:1st, ozone instrument;2nd, container;3 oxygen output pipes;4th, muffler.
Embodiment
To make the object, technical solutions and advantages of the present invention clearer, this preparation method is made below in conjunction with accompanying drawing Further it is described in detail.
The present invention proposes a kind of preparation method of ozone oil lipstick, comprises the technical steps that:
(1) container is set, edible virgin oil is injected in container;
(2) an ozone instrument is set, the oxygen output pipe of ozone instrument is extend into below the edible virgin oil liquid level in container, Multiple helical form aperture auxiliary outlets are partly set below oxygen output pipe liquid level
(3) ozone instrument is opened, so that ozone constantly pours high-concentrated ozone by oxygen output pipe into edible virgin oil, The high-concentrated ozone is sufficiently mixed with edible virgin oil, be fabricated to ozone olive oil, this process is needed 2 days, until olive Olive oil lighter for it is sticky it is yellowish untill;
(4) the ozone olive oil is transferred to sealing container by conduit, the sealing container is inserted into refrigerating chamber, refrigerated Temperature is 5 DEG C, solidifies the ozone olive oil, stand-by;
(5) inserted after smashing caulis lonicerae, Radix Angelicae Sinensis to pieces in sesame oil, immersion 1-5 hours after, small fire be warming up to 100 DEG C decoct to 10-20 minutes, temperature control is carried out to be assisted a ruler in governing a country with liquid tempilstick, is cooled within 100 DEG C, Asian puccoon is added, stirring continues small Fire is decocted, withered to medicine, is then cooled down, filter and remove residue trapped fuel, is added the borneol stirring pulverized and is melted, is fabricated to Groomwell root oil, treats With the caulis lonicerae, Radix Angelicae Sinensis, Asian puccoon, borneol, sesame oil mass ratio are 5:2.5:5:1:70;
(6) beeswax, olive oil are put into vessel in heating, the beeswax is 1 with the mass ratio of the olive oil:1, Bian Jia Hot side stirring, is clayed into power while vitamin E capsule is extruded into liquid, vitamin B6 tablet, and container, the dimension life are added together Plain E, vitamin B6 and beeswax mass ratio are 1:0.1-0.2:20, heating-up temperature is 60 DEG C, until the beeswax is all molten into Liquid, and olive oil are sufficiently mixed, and then add the ozone olive oil being made in step (4), the ozone olive oil and beeswax Mass ratio is 3:1, will the ozone olive oil add container after continue stir, heating until fusing, all as after liquid by In mixing liquid injected plastic lipstick tube;
(7) the canned ozone oil lipstick is put into refrigerator cooled and solidified, temperature is 0 DEG C.
As a kind of preferred scheme, the container sets muffler to be connected to ozone instrument air inlet, forms gas closed Circulation loop.
In addition to ozone olive oil, vitamin E, vitamin B6 are burnt to treatment, lip decortication, improve blood circulation, have Certain effect.Groomwell root oil has a cooling and activating blood, effect of anti-inflammation, and to treatment dermatitis, scald has good effect.
The present invention has equipment simple, saves fund, pollution-free, the high advantage of the ozone oil lipstick stability produced, And it is easy to use, lipstick rotation is outwards back-outed on smearing skin when using.Clinical practice:Treat exfoliative cheilitis, The bacterium such as bicker inflammation, canker sore and burn, diabetes, fungus-caused skin chronic inflammation, can be treated a variety of Disease.
Illustrate the therapeutic effect of the product of the present invention by tests below:
Research object:Selection has a bicker inflammation, the volunteer of canker sore etc. totally 60 people.
Affected part is smeared with embodiment products obtained therefrom respectively, daily 2-3 times~4-6 times, repeats to operate above every time.Test into Row is counted its efficient (%) after 10 days.Criterion of therapeutical effect:
(1) it is obviously improved:Subjective symptoms, which to be had, significantly mitigate or disappear.(2) alleviate:Subjective symptoms has to a certain degree Mitigation but less obvious.(3) it is invalid:Situation does not mitigate substantially or still.(4) deteriorate:Situation becomes worse.
It is obviously improved Alleviate It is invalid Deteriorate Total effective rate
Embodiment 45 9 6 0 90%
As a result show:For there is a bicker inflammation, the patient of canker sore etc. has preferable effect.
Research object:Choosing has the volunteer of fungus-caused skin chronic inflammation etc. totally 60 people.
Affected part is smeared with embodiment products obtained therefrom respectively, daily 2-3 times~4-6 times, repeats to operate above every time.Test into Row is counted its efficient (%) after 20 days.Criterion of therapeutical effect:
(1) it is obviously improved:Subjective symptoms, which to be had, significantly mitigate or disappear.(2) alleviate:Subjective symptoms has to a certain degree Mitigation but less obvious.(3) it is invalid:Situation does not mitigate substantially or still.(4) deteriorate:Situation becomes worse.
It is obviously improved Alleviate It is invalid Deteriorate Total effective rate
Embodiment 41 11 8 0 86.7%
As a result show:For there is the patient of fungus-caused skin chronic inflammation etc., there is preferable effect.
Presently preferred embodiments of the present invention is the foregoing is only, not to limit invention, all spiritual and originals in the present invention Within then, any modifications, equivalent substitutions and improvements made etc. should be included within the scope of the present invention.

Claims (2)

1. a kind of preparation method of ozone oil lipstick, it is characterised in that comprise the technical steps that:
(1) container is set, edible virgin oil is injected in container;
(2) an ozone instrument is set, the oxygen output pipe of ozone instrument is extend into below the edible virgin oil liquid level in container;
(3) ozone instrument is opened, so that ozone constantly pours high-concentrated ozone by oxygen output pipe into edible virgin oil, makes institute State high-concentrated ozone to be sufficiently mixed with edible virgin oil, be fabricated to ozone olive oil, this process is about needed 2-3 days, until olive Olive oil lighter for it is sticky it is yellowish untill;
(4) the ozone olive oil is transferred to sealing container, the sealing container is inserted into refrigerating chamber refrigeration, refrigerated storage temperature is 0 DEG C -5 DEG C, solidify the ozone olive oil, it is stand-by;
(5) inserted after smashing caulis lonicerae, Radix Angelicae Sinensis to pieces in sesame oil, after soaking 1-5 hours, small fire is warming up to 100 DEG C and decocted to 10-20 Minute, it is cooled within 100 DEG C, adds Asian puccoon, stirring continues small fire and decocted, cooling withered to medicine, and remove slag trapped fuel, adds stone roller Broken borneol stirring is melted, and is fabricated to Groomwell root oil, stand-by, and the caulis lonicerae, Radix Angelicae Sinensis, Asian puccoon, borneol, sesame oil mass ratio are 5: 2.5:5:1:70;
(6) Groomwell root oil that beeswax, olive oil and step (5) are made is put into vessel in heating, the beeswax, olive oil with it is described The mass ratio of Groomwell root oil is 2:2:1, heat while stirring, while adding vitamin E, vitamin B6, the beeswax and vitamin E, vitamin B6 mass ratio are 20:1:0.1-0.2, heating-up temperature is 60 DEG C, until the beeswax is all molten into liquid, and olive Olive oil is sufficiently mixed, and then adds the ozone olive oil being made in step (4), and the beeswax quality is 1 with ozone olive oil ratio: 2-3, will the ozone olive oil add container after continue stir, heating until fusing, all as after liquid by mixing liquid In injected plastic lipstick tube;
(7) the canned ozone oil lipstick is put into refrigerator cooled and solidified, temperature is 0 DEG C -5 DEG C.
2. the preparation method of ozone oil lipstick according to claim 1, it is characterised in that the container sets muffler to connect It is connected to ozone instrument air inlet.
CN201710221331.1A 2017-04-06 2017-04-06 A kind of preparation method of ozone oil lipstick Pending CN106943457A (en)

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CN201710221331.1A CN106943457A (en) 2017-04-06 2017-04-06 A kind of preparation method of ozone oil lipstick

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CN201710221331.1A CN106943457A (en) 2017-04-06 2017-04-06 A kind of preparation method of ozone oil lipstick

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107582472A (en) * 2017-10-31 2018-01-16 山东朱氏堂医疗器械有限公司 A kind of skin care compositions, facial mask liquid, facial mask and preparation method thereof
CN108992381A (en) * 2018-10-12 2018-12-14 阿谷巴科技(唐山)有限公司 A kind of preparation method of anion olive oil beauty antimicrobial fluid
CN110339080A (en) * 2019-08-20 2019-10-18 广州华狮化妆品科技有限公司 A kind of lip moisturizing essence dew
CN114288226A (en) * 2021-11-03 2022-04-08 深圳市橘井舒泉技术有限公司 Antibacterial moisturizing lipstick containing ozone oil and preparation method thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107582472A (en) * 2017-10-31 2018-01-16 山东朱氏堂医疗器械有限公司 A kind of skin care compositions, facial mask liquid, facial mask and preparation method thereof
CN108992381A (en) * 2018-10-12 2018-12-14 阿谷巴科技(唐山)有限公司 A kind of preparation method of anion olive oil beauty antimicrobial fluid
CN110339080A (en) * 2019-08-20 2019-10-18 广州华狮化妆品科技有限公司 A kind of lip moisturizing essence dew
CN114288226A (en) * 2021-11-03 2022-04-08 深圳市橘井舒泉技术有限公司 Antibacterial moisturizing lipstick containing ozone oil and preparation method thereof

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Inventor after: Hou Guiying

Inventor after: Jiao Yuwei

Inventor after: Wang Qingli

Inventor after: Wang Chenxue

Inventor after: Zhou Caili

Inventor after: Xu Lihui

Inventor before: Hou Guiying

Inventor before: Jiao Yuwei

Inventor before: Wang Qingli

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Application publication date: 20170714

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