CN101822764A - External patch for treating children anorexia and preparation method thereof - Google Patents

Abstract

The invention relates to an external patch for treating children anorexia and a preparation method thereof, and relates to a medicine for treating children anorexia and a preparation method thereof, raw materials of which comprise radix pseudostellariae, radix codonopsitis, the rhizome of large-headed atractylodes, Tuckahoe, hawthorn, lotus seed, gordon euryale seed, dried orange peel, prepared RHIZOMA PINELLIZE without adju-vant, ebony, cassia seed, hoantchy root, dried immature fruit of citron orange and ledebouriella seseloides and are made into external patch for treating the children anorexia through a special process. The patch is used outside the body, so the external patch is safe and convenient, first pass effect of the medicine on liver and gall, stimulation of stomach and burden of kidney can be prevented, and the herbs which both can be eaten and used as medicine and has soft drug effect are selected, so the external patch is free from irritating the skin, can warm the stomach and is suitable for the anorexia children patients.

Description

External use plaster of treatment infantile anorexia and preparation method thereof

Technical field

The present invention relates to medicament for the treatment of infantile anorexia and preparation method thereof, is a kind of external use plaster for the treatment of infantile anorexia and preparation method thereof specifically.

Background technology

We know that infantile anorexia is meant the symptom that children's's (1-6 year) longer-term diet goes down or is off one's feed.Though be a kind of symptom, a lot of heads of a family think a kind of disease.Some chronic disease, the dyspepsia that causes as digestive tract disease, chronic liver-gallbladder disease, respiratory tract disease etc. or prolonged constipation etc. all become the reason of apositia.But most of infantile anorexias are not because disease causes, are because bad habit, irrational diet, the head of a family nurse the wrong and head of a family and child at heart factor cause.Infantile anorexia is not fearful, but because long-term dysplasia that anorexia causes, poor growth, immunity degradation with bring out the generation of many chronic diseases or infectious disease, people are concerned about very much.Think because various factors is caused insufficiency of the spleen, again because of the insufficiency of the spleen result who has caused the vicious cycle of various diseases in the traditional Chinese medical science.Non-disease has following reason: 1, irregular eating, these variations of gastro-intestinal digestion incompatibility; 2, the nutrition that covets causes taste over-burden; 3, snacks cross cold, too much, the assorted excessively digestive functional disturbance that causes; 4, beverage diet heat is too high, and blood glucose and total protein level are too high, and unconsciously hunger causes and is off one's feed or detests food; 5, diet environment: the only child have a meal no diet atmosphere, play while eating, the head of a family reprimands, indifferent to diet; 6, blindly take medicine, abuse the health product stimulating intestine and stomach, not good to the sense of taste of food.Disease factor: 1, cause that cough and choke makes adverse rising of stomach-QI bitter taste, loss of appetite in crying and screaming; 2, times of common cold is too much, consumes too much, and gastric motility descends, long-pending dyspepsia; 3, peaceful, the poor sleep of the stomachache that causes of various factors, gastrointestinal; 4, the spontaneous perspiration, night sweat, lack of moisture, the parasecretion that cause of various factors, be hard and dry; 5, long-term oral drugs stimulate the caused dyspepsia of liver and gall; 6, the caused sequela of various chronic inflammatory diseases; 7, weak, the insufficiency of stomach of congenital spleen.In treatment, generally not seek the help of western medicine and medical practitioners, and recuperate under medical treatment with Chinese medicine, traditional Chinese medical science medical treatment at first is dialectical, the traditional Chinese medical science thinks that the dialectical of infantile anorexia should be: 1, QI rising in reverse order causes newborn dyspepsia; 2, the long-pending heat that causes of the deficiency of vital energy is just dry; 3, the insufficiency of the spleen lack of appetite that causes is indigestion and loss of appetite; 4, accumulate (wind, cold, summer-heat, wet, medicine) in the malicious heresy that exopathogen causes.On the treatment rule, must adopt: 1, the then pleasant method of QI rising in reverse order person, " people's gas is following for suitable " were both used " sinking " medicine in " ascending, descending, floating, heavy " four property, and as Fructus Aurantii Immaturus etc., prescription is executed and controlled; 2, the method for deficiency of vital energy person's tonify deficiency, " deficiency syndrome should be treated by tonifying method " promptly uses Qi-tonifying drug Radix Pseudostellariae etc.; 3, debate empty person, spleen is opened in the spleen reinforcing spleen invigorating, promptly uses the medicine of the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae strengthening the spleen; 4, in exopathogen was crossed then and to be hindered, the exopathogen of dispelling then used prescriptions such as the Chinese medicine Radix Saposhnikoviae, Fructus Forsythiae of the poison of expelling wind and cold, clearing away summer-heat, dehumidifying, row's medicine.On medication, what reach common recognition is: injection is not as oral, and is oral not as external.Obviously the treatment optimum method of infantile spleen deficiency is an inner disease outer treat, skin loading method.

Summary of the invention

The invention provides a kind of safe, convenient, avoided medicine to stimulate and the burden of kidney to the hepatobiliary first pass effect with to the intestines and stomach, good and the slow soft medicament composing prescription of the property of medicine of the abnormal smells from the patient of selecting food and medicament dual-purpose for use, make not chafe of external use plaster, and the external use plaster of the treatment infantile anorexia of warm taste and preparation method thereof.

Technical solution of the present invention is:

The external use plaster raw material of treatment infantile anorexia contains Radix Pseudostellariae, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Poria, Fructus Crataegi, Semen Nelumbinis, Semen Euryales, Pericarpium Citri Reticulatae, Rhizoma Pinelliae, Fructus Mume, Semen Cassiae, the Radix Astragali, Fructus Aurantii Immaturus, Radix Saposhnikoviae.

Its preparation method is (percentage by weight):

1, get Radix Pseudostellariae 0.3%-0.6%, Radix Codonopsis 0.7%-1.2%, Rhizoma Atractylodis Macrocephalae 0.5%-0.8%, Rhizoma Dioscoreae 0.7%-1.2%, Poria 0.5%-0.8% cleans, add Sal 0.7%-1.2%, add after 40 ℃-50 ℃ warm water 75%-77% soaks 3, the ethanol 18%-20% that adds 80 °-90 °, soak filtration on the 10th again, it is stand-by to get medicated wine;

2, get Semen Nelumbinis 0.3%-0.6%, Fructus Mume 0.3%-0.6%, Semen Euryales 0.5%-0.8%, Semen Cassiae 0.7%-1.2%, Fructus Crataegi 1.1%-1.6% cleans, add water purification 57%-59%, add 50 ° of-60 ° of acetic acid 18%-20%, soak and add 80-90 ° of ethanol 18%-20% after 3 days again, soak filtration on the 10th again, it is stand-by to get medicated wine;

3, get Pericarpium Citri Reticulatae 0.5%-0.8%, Radix Astragali 0.7%-1.2%, Radix Saposhnikoviae 0.5%-0.8%, Rhizoma Pinelliae 0.7%-1.2%, Fructus Aurantii Immaturus 0.5%-0.8% cleans, add water purification 57%-59%, add Mel 18%-20% (, soak and add 80-90 ° of ethanol 18%-20% after 5 days again, soak filtration on the 10th, it is stand-by to get medicated wine;

4, get the medicated wine 30%-35% of the first step, add the medicated wine 30%-35% in second step, the medicated wine 30%-35% that added for the 3rd step stirs evenly, and adds sodium bicarbonate 0.4%-0.7% again, gets medicated wine and closes liquid;

5, the medicated wine of getting for the 4th step close liquid through centrifugal filter, filter pressing each once, must clarifying medicated wine, to close liquid stand-by;

6, the 5th clarification medicated wine that goes on foot is closed liquid and add thermal distillation, recovered alcohol is concentrated into the 70%-80% that clarification medicated wine closes liquid, and it is stand-by to get concentrated solution;

7, get the concentrated solution 48.5%-51% in the 6th step, glycerol adding 48.5%-51% adds hydroxylated cellulose 0.3%-0.7% again, the stirring and emulsifying of heating, ointment is deposited after 7 days and is encapsulated manufactured goods.

The invention has the beneficial effects as follows, Radix Pseudostellariae is mended strengthening spleen and lung, supplementing QI for promoting the production of body fluid, control cough due to deficiency of the lung, insufficiency of the spleen lack of appetite, cardiopalmus, palpitation with a distress feeling, edema, quench one's thirst, spirit is tired, can gastric acid secretion, slow down the gastric emptying time, improve the intestinal propulsion rate, increase the absorption of small intestinal, suppress enterospasm, so there is facilitating digestion to absorb glucose, appetite strengthening, the effect of pain relieving antidiarrheal.The Radix Codonopsis invigorating the spleen and replenishing QI, promote the production of body fluid, anti-weakness of the spleen and stomach, deficiency of both QI and blood, fatigue and lack of strength, lack of appetite are thirsty, chronic diarrhea proctoptosis etc., the pure and mild soaking object of Radix Codonopsis root slightly increases erythrocyte and hemoglobin, blood glucose there is the raising effect, adrenolytic is arranged, buck functionality is arranged, compound recipe uses has the property of enriching blood, treatment chlorosis, leukemia, adenopathy, rickets are controlled asthenia internal injury, intestinal cold in the stomach, sliding chronic dysentery, asthma excessive thirst, the heating spontaneous perspiration etc. of rushing down.Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI; the dampness diuretic; hidroschesis is antiabortive; be used for insufficiency of the spleen lack of appetite; abdominal distention is had loose bowels; the phlegm retention vertigo and palpitation; edema; spontaneous perspiration; frequent fetal movement; the adjustment gastrointestinal function is arranged; Rhizoma Atractylodis Macrocephalae decocting liquid under normal circumstances has excitation to intestinal tube; antiulcer; gastric mucosa injury there is inhibitory action; reduce gastric acidity; reduce gastric acid and pepsic output; and liver function protecting, alleviate hepatic glycogen and reduce and the hepatocellular degeneration necrosis, promote hepatocyte to increase; the ALT of rising is descended; enhancing immunity is arranged; the antioxidant and anti-aging effect, resisting fatigue has the adrenal cortex reinforcing function; strengthen hemopoietic function, compound recipe uses to be commonly used for and promotes diet and blood sugar lowering; anticoagulation; antitumor action.The Rhizoma Dioscoreae invigorating the spleen and benefiting QI, the kidney invigorating and essence nourishing, control trusted subordinate's deficiency-distension, deadly cold hand and foot, loss of appetite, it is many to control frequent micturition, expectorant wind dyspnea with rapid respiration, weakness of the spleen and stomach, anorexia, damp and hot diarrhea due to deficiency, strengthening the spleen and stomach, aid digestion, starch-containing enzyme in the Rhizoma Dioscoreae, materials such as polyphenol oxidase, favourable taste digestive and absorptive functions, essence is filled in the kidney invigorating, contain multiple nutrients in the Rhizoma Dioscoreae, the reinforcement human body is arranged, and kidney tonifying is mended smart effect, and Rhizoma Dioscoreae contains Saponin, lymphatic temperament has lubricated, moisten effect, but so lung benefiting gas, support lung yin, the treatment deficiency of the lung, the disease of phlegmatic cough chronic cough has mucus albumen in the Rhizoma Dioscoreae, vitamin and trace element can effectively stop the precipitation of blood fat in blood vessel wall, prevention painstaking effort disease obtains viscosity reduction, blood fat reducing, intelligence promoting and the mind tranquilizing, effect of prolonging life.Poria promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming; Poria has diuresis; give rabbit with Poria alcohol extraction, the injection of distillation back; experimental results show that; the urine amount increases after the medication; studies have shown that all has inhibitory action to staphylococcus aureus, escherichia coli, Bacillus proteus; the facilitating digestion liver protection effect is arranged, and Poria can reduce gastric acid and hepatic injury is had protective effect, reduces glutamate pyruvate transaminase; prevent hepatic necrosis; antitumor action is arranged, and pachyman has showed intensive antitumor action in animal experiment; enhancing immunity, pachyman have the raising immunity.The Fructus Crataegi appetite-stimulating indigestion-relieving, change the removing food stagnancy that stagnates, promoting blood circulation to remove blood stasis, the circulation of qi promoting of reducing phlegm, be used for meat stagnation, lump in the abdomen, the abdominal distention feeling of fullness, stasis of blood resistance stomachache, phlegm retention, have loose bowels, discharging fresh blood stool etc., Fructus Crataegi can prevent and treat cardiovascular disease, has blood vessel dilating, coronary blood flow increasing, improve the heart vigor, plant nervous system in the excitement, bring high blood pressure down and cholesterol, vessel softening and diuretic sedation, Fructus Crataegi has cardiotonic, also helpful to senile heart disease, the energy appetite-stimulating indigestion-relieving, particularly better to the meat stagnation effect, the effect that blood circulation promoting and blood stasis dispelling is arranged, help to remove the local stasis of blood state, traumatic injury there is assosting effect, the flavonoid vitamin C that contains in the Fructus Crataegi, the growth of free radical can be blocked and reduce to materials such as carotene, the immunity of energy enhancing body has health care anti-ageing, antitumaous effect.Semen Nelumbinis clear away heart-fire and are amusing, invigorating middle warmer is reposed, spleen benefiting and stimulating the appetite, the antidiarrheal controlling nocturnal emission with astringent drugs, the kidney tonifying leukorrhagia stopping, cancer-resisting, Semen Nelumbinis are apt to the tonifying five ZANG-organs deficiency, tonneau twelve regular channels QI and blood, the contained oxoushinsunine of Semen Nelumbinis has inhibitory action to nasopharyngeal carcinoma, everything has constituted the alimentary health-care function of the cancer-resisting of Semen Nelumbinis, the contained noncrystal alkaloid of Semen Nelumbinis N-9 has hypotensive effect, the heart strengthening and the mind tranquilizing effect is arranged, the contained alkaloid of Plumula Nelumbinis has significant cardiotonic, and liensinine has stronger anticalcium and antiarrhythmic effect, contained Raffinose in the Semen Nelumbinis, it is the tonic that suits the taste of both old and young, for the eipathia asthenia person, nutrient excellent product especially is for the teenager good tonify deficiency effect of having suffered from a deficiency of the kidney.Semen Euryales invigorating the spleen and replenishing QI, supplementing the kidney to control the nocturnal, invigorating the spleen and replenishing QI is for nourishing strong food, the spleen reinforcing QI invigorating, not worse than Semen Nelumbinis, tonifying the kidney to consolidate the essence to the weak insomnia of children's, is cried and frequent micturition and the enuresis function that improves significantly night, control chronic diarrhea, child's chronic abdominal pain, diarrhoea, chronic enteritis and diarrhea before dawn had good therapeutical effect; Promote the effect of upgrowth and development of children, make the child full of vitality, promote to grow up.Pericarpium Citri Reticulatae is regulated the flow of vital energy, reduce phlegm, with in, dampness, cure mainly the wrist distention and fullness in the abdomen or the pain of stagnation of QI in spleen and stomach, dyspepsia, abdominal distention uncomfortable in chest in the turbid damp resistance, indigestion and loss of appetite loose stool, phlegm-damp is stopped up the cough of lung and is panted, the bitter substance of Pericarpium Citri Reticulatae is that Fructus Citri Limoniae glycosides and bitter principle are representative " limonoid ", this limonoid flavor is gentle, soluble in water, help digesting and assimilating of food, when being used to cook, its bitterness and other tastes are in harmonious proportion, volatile oil in the Pericarpium Citri Reticulatae, hesperidin, dimension B, dimension C has gentle the stimulation to gastrointestinal tract, but the secretion of facilitating digestion liquid, the pneumatosis in eliminating intestinal tube week, appetite strengthening has the ventilation spleen invigorating, drying dampness to eliminate phlegm, separate greasy lasting, the effect of stopping nausea and vomiting by lowering the adverse flow of QI.The Rhizoma Pinelliae drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, control the damp-phlegm cold drink, vomiting, regurgitation, cough excessive phlegm, the chest and diaphragm distension, the syncope due to accumulation of phlegm headache, dizzy sleeplessness, outer subduing inflammation, be used for the abundant expectoration cough, the Rhizoma Pinelliae is dry and function is reduced phlegm, the expectorant of its instituteization, with not removing dampness of spleen, poly-form expectorant the person is main, for controlling the key medicine of damp-phlegm, be applicable to that the damp-phlegm heap soil or fertilizer over and around the roots stagnates, cough with dyspnea etc., it is vexed to be used for breast wrist spleen, the thoracic obstruction, diseases such as blocked-up chest, the hot logical temperature of loosing of Rhizoma Pinelliae function, reduce phlegm, dampness, so can be used for the expectorant internal resistance, breast wrist painful abdominal mass is vexed etc., is used for adverse rising of stomach-QI, nausea and vomiting, the Rhizoma Pinelliae have good stopping nausea and vomiting by lowering the adverse flow of QI, can be used for multiple vomiting disease, join Sorghum vulgare Pers. with unable to sleep soundly, join sulfur and control gastric acid deficiency, the disease of dysporia with controlling discomfort in the stomach.The cough-relieving of Fructus Mume antidiarrheal, the hemostasis of promoting the production of body fluid, the astringing intestine to stop diarrhea of astringing the lung, relieving colic caused by ascaris, control that chronic cough of deficiency lung, chronic dysentery chronic diarrhea, deficiency-heat are quenched one's thirst, ascarid vomiting stomachache, ascariasis of biliary tract, be suitable for the people of deficiency-heat excessive thirst, anorexia lack of appetite, achlorhydria (comprising the atrophic gastritis hypochlorhydria), dyspepsia, chronic dysentery enteritis, the person that is applicable to the biliary tract ascarid, be suitable for various inflammation, as dysentery bacterium, escherichia coli, Bacillus typhi, Salmonella paratyphi, bordetella pertussis, meningococcus, tubercule bacillus also there is inhibitory action, fungus, frame shape surface tinea bacterium are also had inhibitory action.Fructus Mume has calcium antagonism, and immunity is improved function again.The Semen Cassiae liver heat removing, make eye bright, relieving constipation, be used to have a headache dizzy, conjunctival congestion is dim-sighted, constipation, modern study shows, Semen Cassiae also contains Liu body chemical compound, chrysophanol, emodin etc. except that containing saccharide, protein, fat, also have human body must get trace elements iron, zinc, manganese, copper, nickel, cobalt, molybdenum etc., human body had relieving asthma, function of gallbladder promoting, protect the liver, the blood pressure lowering effect, and necessarily antibiotic, antiinflammation are arranged, and also have cholesterol reducing and cardiotonic, illustrate that Semen Cassiae has the effect of the multiple disease of control.Fructus Aurantii Immaturus dissipating phlegm and resolving masses, dispelling the stagnated QI removing food stagnancy are used for stopping in stagnant, stagnate the vapour lock thoracic obstruction and gastroptosis of weight, constipation, expectorant after the feeling of fullness stomachache, dysentery, and there is contraction in the uterus, and intestinal tube and stomach are had the effect of the motion contraction rhythm and pace of moving things, and heart and blood vessel are had regulating action.Radix Saposhnikoviae expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion, can diaphoresis again can hidroschesis, can antidiarrheal relieving constipation again, can only transfer and logical blood, can also be analgesic, the effect of analgesia, calmness and convulsion, antiinflammatory, resisting pathogenic microbes.Radix Astragali invigorating QI to consolidate the body surface resistance, diuresis poison holding are used for that the deficiency of vital energy is weak, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, blood deficiency and yellow complexion, interior-heat quench one's thirst etc.External medication, safety, convenient has avoided medicine to stimulate and the burden of kidney to the hepatobiliary first pass effect with to the intestines and stomach, and the abnormal smells from the patient of selecting food and medicament dual-purpose for use is good and the slow soft medicament composing prescription of the property of medicine makes not chafe of external use plaster, and warm taste.The present invention is applicable to the infantile anorexia patient.

The specific embodiment

Embodiment 1

A kind of external use plaster for the treatment of infantile anorexia, raw material contains Radix Pseudostellariae, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Poria, Fructus Crataegi, Semen Nelumbinis, Semen Euryales, Pericarpium Citri Reticulatae, Rhizoma Pinelliae, Fructus Mume, Semen Cassiae, the Radix Astragali, Fructus Aurantii Immaturus, Radix Saposhnikoviae.

Its preparation method is (percentage by weight):

1, getting Radix Pseudostellariae 0.3%, Radix Codonopsis 0.7%, the Rhizoma Atractylodis Macrocephalae 0.5%, Rhizoma Dioscoreae 0.7%, Poria 0.5% cleans, add Sal 0.7%, add after 40 ℃-50 ℃ warm water 76.6% soaks 3, add 80 °-90 ° ethanol 20%, soak filtration on the 10th again, it is stand-by to get medicated wine;

2, get Semen Nelumbinis 0.3%, Fructus Mume 0.4%, Semen Euryales 0.5%, Semen Cassiae 0.7%, Fructus Crataegi 1.1% and clean, add water purification 59%, adds 50 ° of-60 ° of acetic acid 20%, soak and add 80-90 ° of ethanol 18% after 3 days again, soak filtration on the 10th again, must medicated wine stand-by;

3, get Pericarpium Citri Reticulatae 0.5%, the Radix Astragali 0.7%, Radix Saposhnikoviae 0.6%, Rhizoma Pinelliae 0.7%, Fructus Aurantii Immaturus 0.5% and clean, add water purification 57%, after adding Mel 20% and soaking 5, adds 80-90 ° of ethanol 20%, soak filtration on the 10th, must medicated wine stand-by;

4, get the medicated wine 30% of the first step, add the medicated wine 35% in second step, the medicated wine 34.6% that added for the 3rd step stirs evenly, and adds sodium bicarbonate 0.4% again, gets medicated wine and closes liquid;

5, the medicated wine of getting for the 4th step close liquid through centrifugal filter, filter pressing each once, must clarifying medicated wine, to close liquid stand-by;

6, the 5th clarification medicated wine that goes on foot is closed liquid and add thermal distillation, recovered alcohol is concentrated into the 70%-80% that clarification medicated wine closes liquid, and it is stand-by to get concentrated solution;

7, get the concentrated solution 48.5% in the 6th step, glycerol adding 51% adds hydroxylated cellulose 0.5% again, the stirring and emulsifying of heating, ointment is deposited after 7 days and is encapsulated manufactured goods.

Embodiment 2

The preparation method of the external use plaster of treatment infantile anorexia is (percentage by weight):

1, getting Radix Pseudostellariae 0.6%, Radix Codonopsis 1.2%, the Rhizoma Atractylodis Macrocephalae 0.8%, Rhizoma Dioscoreae 1.2%, Poria 0.8% cleans, add Sal 1.2%, add after 40 ℃-50 ℃ warm water 75% soaks 3, add 80 °-90 ° ethanol 19.2%, soak filtration on the 10th again, it is stand-by to get medicated wine;

2, get Semen Nelumbinis 0.6%, Fructus Mume 0.6%, Semen Euryales 0.8%, Semen Cassiae 1.2%, Fructus Crataegi 1.6% and clean, add water purification 57%, adds 50 ° of-60 ° of acetic acid 19%, soak and add 80-90 ° of ethanol 19.2% after 3 days again, soak filtration on the 10th, must medicated wine stand-by;

3, get Pericarpium Citri Reticulatae 0.8%, the Radix Astragali 1.2%, Radix Saposhnikoviae 0.8%, Rhizoma Pinelliae 1.2%, Fructus Aurantii Immaturus 0.8% and clean, add water purification 58.2%, add Mel 18%, soak and add 80-90 ° of ethanol 19% after 5 days again, soak filtrations on the 10th, must medicated wine stand-by;

4, get the medicated wine 34.5% of the first step, add the medicated wine 30% in second step, the medicated wine 35% that added for the 3rd step stirs evenly, and slowly adds sodium bicarbonate 0.5%, gets medicated wine and closes liquid;

5, the medicated wine of getting for the 4th step close liquid through centrifugal filter, filter pressing each once, must clarifying medicated wine, to close liquid stand-by;

6, the 5th clarification medicated wine that goes on foot is closed liquid and add thermal distillation, recovered alcohol is concentrated into the 70%-80% that clarification medicated wine closes liquid, and it is stand-by to get concentrated solution;

7, get the concentrated solution 51% in the 6th step, glycerol adding 48.7% adds hydroxylated cellulose 0.3% again, the stirring and emulsifying of heating, ointment is deposited after 7 days and is encapsulated manufactured goods.

Embodiment 3

The preparation method of the external use plaster of treatment infantile anorexia is (percentage by weight):

1, get Radix Pseudostellariae 0.5%, Radix Codonopsis 1%, the Rhizoma Atractylodis Macrocephalae 0.6%, Rhizoma Dioscoreae 1.1%, Poria 0.7% and clean, add Sal 1.1%, adds after 40 ℃-50 ℃ warm water 77% soaks 3, add 80 °-90 ° ethanol 18%, soak filtration on the 10th again, must medicated wine stand-by;

2, get Semen Nelumbinis 0.5%, Fructus Mume 0.3%, Semen Euryales 0.7%, Semen Cassiae 1%, Fructus Crataegi 1.5% and clean, add water purification 58%, adds after 50 ° of-60 ° of acetic acid 18% soak 3, add 80-90 ° of ethanol 20% again, soak filtration on the 10th, must medicated wine stand-by;

3, get Pericarpium Citri Reticulatae 0.7%, the Radix Astragali 1%, Radix Saposhnikoviae 0.5%, Rhizoma Pinelliae 1.1%, Fructus Aurantii Immaturus 0.7% and clean, add water purification 59%, add Mel 19%, soak and add 80-90 ° of ethanol 18% after 5 days again, soak filtrations on the 10th, must medicated wine stand-by;

4, get the medicated wine 35% of the first step, add the medicated wine 34.3% in second step, the medicated wine 30% that added for the 3rd step stirs evenly, and adds sodium bicarbonate 0.7% again, gets medicated wine and closes liquid;

5, the medicated wine of getting for the 4th step close liquid through centrifugal filter, filter pressing each once, must clarifying medicated wine, to close liquid stand-by;

6, the 5th clarification medicated wine that goes on foot is closed liquid and add thermal distillation, recovered alcohol is concentrated into the 70%-80% that clarification medicated wine closes liquid, and it is stand-by to get concentrated solution;

7, get the concentrated solution 50.8% in the 6th step, glycerol adding 48.5% adds hydroxylated cellulose 0.7% again, the stirring and emulsifying of heating, ointment is deposited after 7 days and is encapsulated manufactured goods.

Using method: this patch is made plaster, be affixed on children's's stomach abdominal part.Once a day, about one time four hours.

Use this patch treat 100 surplus routine infantile anorexia patient, total effective rate reaches 90%, therapeutic effect is good.

Claims (2)

1. external use plaster for the treatment of infantile anorexia, it is characterized in that: raw material contains Radix Pseudostellariae, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Poria, Fructus Crataegi, Semen Nelumbinis, Semen Euryales, Pericarpium Citri Reticulatae, Rhizoma Pinelliae, Fructus Mume, Semen Cassiae, the Radix Astragali, Fructus Aurantii Immaturus, Radix Saposhnikoviae.

2. the preparation method of the external use plaster of treatment infantile anorexia according to claim 1 is characterized in that (percentage by weight):

1, get Radix Pseudostellariae 0.3%-0.6%, Radix Codonopsis 0.7%-1.2%, Rhizoma Atractylodis Macrocephalae 0.5%-0.8%, Rhizoma Dioscoreae 0.7%-1.2%, Poria 0.5%-0.8% cleans, add Sal 0.7%-1.2%, add after 40 ℃-50 ℃ warm water 75%-77% soaks 3, the ethanol 18%-20% that adds 80 °-90 °, soak filtration on the 10th again, it is stand-by to get medicated wine;

2, get Semen Nelumbinis 0.3%-0.6%, Fructus Mume 0.3%-0.6%, Semen Euryales 0.5%-0.8%, Semen Cassiae 0.7%-1.2%, Fructus Crataegi 1.1%-1.6% cleans, add water purification 57%-59%, add 50 ° of-60 ° of acetic acid 18%-20%, soak and add 80-90 ° of ethanol 18%-20% after 3 days again, soak filtration on the 10th again, it is stand-by to get medicated wine;

3, get Pericarpium Citri Reticulatae 0.5%-0.8%, Radix Astragali 0.7%-1.2%, Radix Saposhnikoviae 0.5%-0.8%, Rhizoma Pinelliae 0.7%-1.2%, Fructus Aurantii Immaturus 0.5%-0.8% cleans, add water purification 57%-59%, add Mel 18%-20%, soak and add 80-90 ° of ethanol 18%-20% after 5 days again, soak filtration on the 10th, it is stand-by to get medicated wine;

4, get the medicated wine 30%-35% of the first step, add the medicated wine 30%-35% in second step, the medicated wine 30%-35% that added for the 3rd step stirs evenly, and adds sodium bicarbonate 0.4%-0.7% again, gets medicated wine and closes liquid;

5, the medicated wine of getting for the 4th step close liquid through centrifugal filter, filter pressing each once, must clarifying medicated wine, to close liquid stand-by;

6, the 5th clarification medicated wine that goes on foot is closed liquid and add thermal distillation, recovered alcohol is concentrated into the 70%-80% that clarification medicated wine closes liquid, and it is stand-by to get concentrated solution;

7, get the concentrated solution 48.5%-51% in the 6th step, glycerol adding 48.5%-51% adds hydroxylated cellulose 0.3%-0.7% again, the stirring and emulsifying of heating, ointment is deposited after 7 days and is encapsulated manufactured goods.