CN106925438A - A kind of low capacity blood plasma separate cup based on ultra-sonic welding techniques - Google Patents
A kind of low capacity blood plasma separate cup based on ultra-sonic welding techniques Download PDFInfo
- Publication number
- CN106925438A CN106925438A CN201710196204.0A CN201710196204A CN106925438A CN 106925438 A CN106925438 A CN 106925438A CN 201710196204 A CN201710196204 A CN 201710196204A CN 106925438 A CN106925438 A CN 106925438A
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- China
- Prior art keywords
- cup
- ultra
- acquisition port
- blood plasma
- low capacity
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Links
- 210000002381 plasma Anatomy 0.000 title claims abstract description 41
- 238000003466 welding Methods 0.000 title claims abstract description 35
- 238000000034 method Methods 0.000 title claims abstract description 26
- 230000003068 static effect Effects 0.000 claims abstract description 25
- 230000008569 process Effects 0.000 claims abstract description 6
- 210000003205 muscle Anatomy 0.000 claims description 16
- 210000004369 blood Anatomy 0.000 claims description 9
- 239000008280 blood Substances 0.000 claims description 9
- 238000007789 sealing Methods 0.000 claims description 8
- 239000002002 slurry Substances 0.000 claims 1
- 238000000338 in vitro Methods 0.000 abstract description 6
- 238000002560 therapeutic procedure Methods 0.000 abstract description 4
- 101150038956 cup-4 gene Proteins 0.000 description 12
- 238000005516 engineering process Methods 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000000926 separation method Methods 0.000 description 2
- 101100327917 Caenorhabditis elegans chup-1 gene Proteins 0.000 description 1
- 206010021137 Hypovolaemia Diseases 0.000 description 1
- 238000004026 adhesive bonding Methods 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000010030 laminating Methods 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B7/00—Elements of centrifuges
Landscapes
- External Artificial Organs (AREA)
Abstract
Present invention is disclosed a kind of low capacity blood plasma separate cup based on ultra-sonic welding techniques, including static head, obturating cup, cup lid, cup, cup core and central tube, one end of the central tube is arranged at bottom of cup center, the cup core is arranged at the neck of the central tube and is located at the openend lower section of the cup, the static head lower end is correspondingly arranged on acquisition port upper cover, the lower end of the acquisition port upper cover is located in cup lid, acquisition port lower cover is additionally provided with the acquisition port upper cover, the upper end of the acquisition port lower cover is embedded in interference fit in the groove of static overhead inwall and fixes, the lower end of the acquisition port lower cover is located at the lower section of the acquisition port upper cover lower end, it is arranged at the top of the central tube in the acquisition port lower cover and is closely connected.The present invention substantially reduces the in vitro amount of single cycle;Adhesion process is not used inside cup, throughput rate is improved, the security of therapeutic process is improve.
Description
Technical field
It is particularly a kind of with blood separator matching used based on ultra-sonic welding techniques the present invention relates to medicine equipment
Low capacity blood plasma separate cup.
Background technology
Disposable blood plasma separate cup is to carry out one of means of blood plasma separation in modern biomedical engineering field, its mechanism
Mainly centrifuge drives Centrifuge Cup to rotate at a high speed, and Centrifuge Cup drives the whole blood that with the addition of anti-coagulants in cup to rotate at a high speed, profit
It is different with plasma density with haemocyte under this state, and mutual exclusive speciality, make haemocyte and blood plasma in separate cup lossless
Separate, so as to extract blood plasma.At present, blood plasma separation field generally using 275mL internal capacities blood plasma separate cup, and shaping and
Assembly technology is similar.First, when sampled plasma or plasma exchange is carried out, single is followed the blood plasma separate cup of 275mL specifications
Ring blood is measured in 500mL or so in vitro, measures in vitro larger, is treated to Hypovolemia patient and less than 12 years old minor
When, patient easily occurs uncomfortable or expendable infringement is caused to patient.Secondly, blood plasma separate cup inside is a large amount of using bonding
, easily there is bubble or degumming at laminating position in technique, causes sealing not high, and influence is used, meanwhile, bonding production technology is steady
It is qualitative not high, and production efficiency is low, substantially increases production cost.
The content of the invention
It is an object of the invention to provide a kind of in vitro amount for substantially reducing single cycle;Do not used inside cup gluing
Technique, improves throughput rate, and the low capacity blood plasma based on ultra-sonic welding techniques that improve the security of therapeutic process is separated
Cup.
The technical scheme is that, a kind of low capacity blood plasma separate cup based on ultra-sonic welding techniques, including static head,
Obturating cup, acquisition port upper cover, acquisition port lower cover, cup lid, cup, cup core and central tube, the static head, obturating cup, cup lid
And cup sets gradually from top to bottom, the upper end of the acquisition port lower cover is embedded in interference in the groove of static overhead inwall
Cooperation is fixedly connected so that form hollow pipeline, the acquisition port upper cover bag under acquisition port between cover outer wall and static head inwall
Wrap up in and be arranged under the acquisition port cover outer surface and be located in the hollow pipeline, the central tube is by interference fit and collection
Mouth lower cover is connected with one heart, and the cup core is arranged at the neck of the central tube and is located at the opening of the cup by interference fit
End lower section, the cup lid is fixedly connected with cup by ultra-sonic welded, and the space between the cup core and cup lid forms blood plasma and receives
Collection chamber, the static overhead is horizontally arranged with whole blood inlet, and the static first side is additionally provided with plasma outlet port.
In a preferred embodiment of the present invention, be also correspondingly arranged between the obturating cup and cup lid liner and
Sealing ring, sealing ring and liner use interference fit.
In a preferred embodiment of the present invention, blood plasma overflow ducts are provided with the cup core.
In a preferred embodiment of the present invention, the plasma outlet port is correspondingly arranged with hollow pipeline.
5th, the low capacity blood plasma separate cup based on ultra-sonic welding techniques according to claim 1, it is characterised in that:Institute
State cup lid and the connection end of cup is provided with welding muscle, and cup lid is fixedly connected with cup by Ultrasonic welding processes.
In a preferred embodiment of the present invention, the welding muscle includes second weldering in the first welding muscle of inner side and outside
Connect muscle.
In a preferred embodiment of the present invention, interference fit between the cup and cup core, the cup is total to cup core
It is the chamber of 125mL with internal capacity is formed.
Of the present invention is a kind of low capacity blood plasma separate cup based on ultra-sonic welding techniques, and the present invention substantially reduces list
The in vitro amount of secondary circulation;Adhesion process is not used inside cup, throughput rate is improved, the security of therapeutic process is improve.
Brief description of the drawings
Fig. 1 is the sectional view in the preferred embodiment of low capacity blood plasma separate cup one of the present invention based on ultra-sonic welding techniques;
Fig. 2 is the partial enlarged drawing of Fig. 1 static heads point;
Fig. 3 is the partial enlarged drawing of Fig. 1 cup lids and cup coupling part.
Specific embodiment
Presently preferred embodiments of the present invention is described in detail below so that advantages and features of the invention can be easier to by
It will be appreciated by those skilled in the art that apparent clearly being defined so as to be made to protection scope of the present invention.
Of the present invention is a kind of low capacity blood plasma separate cup based on ultra-sonic welding techniques, such as Fig. 1 combinations Fig. 2 and Fig. 3
It is shown, including static first 1, obturating cup 2, acquisition port upper cover 7, acquisition port lower cover 8, cup lid 3, cup 4, cup core 5 and central tube
6, described static first 1, obturating cup 2, cup lid 3 and cup 4 set gradually from top to bottom, the upper end of the acquisition port lower cover 8
Interference fit is fixedly connected in the groove of static first 1 top inner wall of insertion so that the outer wall of acquisition port lower cover 8 and static first 1 inwall
Between form hollow pipeline, the parcel of acquisition port upper cover 7 is arranged at the outer surface of acquisition port lower cover 8 and positioned at described hollow
In pipeline, the central tube 6 is connected by interference fit with acquisition port lower cover 8, and with one heart, the cup core 5 passes through interference fit
It is arranged at the neck of the central tube 6 and is located at the openend lower section of the cup 1, the cup lid 3 and cup 4 passes through ultrasonic bond
Connect and be fixedly connected, the space between the cup core 5 and cup lid 3 forms plasma collection chamber 13, the static first 1 top horizontally set
There is whole blood inlet 9, static first 1 side is additionally provided with plasma outlet port 10.
Also it is correspondingly arranged on liner 11 and sealing ring 12 between the obturating cup 2 and cup lid 3, sealing ring 12 and close
Envelope pad 11 uses interference fit.
Plasma collection chamber 13 is formed between the cup core 5 and cup lid 3.
Blood plasma overflow ducts 14 are provided with the cup core 5.
The plasma outlet port 10 is correspondingly arranged with hollow pipeline.
The connection end of the cup lid 3 and cup 4 is provided with welding muscle, and by Ultrasonic welding processes by cup lid 3 and cup 4
It is fixedly connected.
The welding muscle includes the second welding muscle 16 in the first welding muscle 15 of inner side and outside.
Interference fit between the cup 4 and cup core 5, the cup 4 is collectively forming internal capacity for 125mL with cup core 5
Chamber.
The cylindrical portions outside dimension of cup core 5 is 42.5mm, and internal diameter size is 40mm, and inside and outside pattern draft is 1.5 degree,
Interference fit between cup core 5 and cup 4, the two is collectively forming the chamber that internal capacity is 125mL.This product and existing blood point
Disembarking flexibly to support the use, and the outer dia of cup 4 is 83.5mm, match with blood separator alms bowl set internal diameter.
The interference fit schematic diagram between static first 1 and acquisition port lower cover 8 is illustrated in figure 2, by under acquisition port before assembling
Cover 8 is placed into dryer and is warming up to 55 DEG C, will be placed into high-low temperature chamber to 5 comprising static first 1 other assemblies
DEG C, static first 1 and the mating surface of acquisition port lower cover 8 are compressed(Interference fit), meanwhile, lift the two using principle of expanding with heat and contracting with cold
Locking degree.
Cup lid 3 and cup 4 before processing are illustrated in figure 3, cup lid 3 is provided with the first welding muscle 15 and the outside of inner side
Second welding muscle 16, the first welding muscle 15 ensures the sealing of cup lid 3 and cup 4, and the second welding muscle 16 improves cup lid 3 and cup
4 intensity.
Of the present invention is a kind of low capacity blood plasma separate cup based on ultra-sonic welding techniques, and the present invention substantially reduces list
The in vitro amount of secondary circulation;Adhesion process is not used inside cup, throughput rate is improved, the security of therapeutic process is improve.
Specific embodiment of the invention is the foregoing is only, but protection scope of the present invention is not limited thereto, it is any
Those of ordinary skill in the art disclosed herein technical scope in, the change that can expect without creative work or
Replace, should all be included within the scope of the present invention.Therefore, protection scope of the present invention should be limited with claims
Fixed protection domain is defined.
Claims (7)
1. a kind of low capacity blood plasma separate cup based on ultra-sonic welding techniques, including static head, obturating cup, acquisition port upper cover, adopt
Collection mouth lower cover, cup lid, cup, cup core and central tube, the static head, obturating cup, cup lid and cup are from top to bottom successively
Set, the upper end of the acquisition port lower cover is embedded in interference fit in the groove of static overhead inwall and is fixedly connected so that adopt
Hollow pipeline is formed under Ji Kou between cover outer wall and static head inwall, the acquisition port upper cover parcel is arranged under the acquisition port
Cover outer surface is simultaneously located in the hollow pipeline, and the central tube is connected by the way that interference fit is concentric with acquisition port lower cover, described
Cup core is arranged at the neck of the central tube and is located at the openend lower section of the cup, the cup lid and cup by interference fit
Body is fixedly connected by ultra-sonic welded, and the space between the cup core and cup lid forms plasma collection chamber, the static overhead
Whole blood inlet is horizontally arranged with, the static first side is additionally provided with plasma outlet port.
2. the low capacity blood plasma separate cup based on ultra-sonic welding techniques according to claim 1, it is characterised in that:It is described close
Liner and sealing ring are also correspondingly arranged between envelope bowl and cup lid, sealing ring and liner use interference fit.
3. the low capacity blood plasma separate cup based on ultra-sonic welding techniques according to claim 1, it is characterised in that:The cup
Blood plasma overflow ducts are provided with core.
4. the low capacity blood plasma separate cup based on ultra-sonic welding techniques according to claim 1, it is characterised in that:The blood
Slurry outlet is correspondingly arranged with hollow pipeline.
5. the low capacity blood plasma separate cup based on ultra-sonic welding techniques according to claim 1, it is characterised in that:The cup
Lid is provided with welding muscle with the connection end of cup, and cup lid is fixedly connected with cup by Ultrasonic welding processes.
6. the low capacity blood plasma separate cup based on ultra-sonic welding techniques according to claim 5, it is characterised in that:The weldering
Connect the second welding muscle of first welding muscle and outside of the muscle including inner side.
7. the low capacity blood plasma separate cup based on ultra-sonic welding techniques according to claim 1, it is characterised in that:The cup
Interference fit between body and cup core, the cup is collectively forming the chamber that internal capacity is 125mL with cup core.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710196204.0A CN106925438B (en) | 2017-03-29 | 2017-03-29 | Small-capacity plasma separation cup based on ultrasonic welding technology |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710196204.0A CN106925438B (en) | 2017-03-29 | 2017-03-29 | Small-capacity plasma separation cup based on ultrasonic welding technology |
Publications (2)
Publication Number | Publication Date |
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CN106925438A true CN106925438A (en) | 2017-07-07 |
CN106925438B CN106925438B (en) | 2023-12-15 |
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Application Number | Title | Priority Date | Filing Date |
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CN201710196204.0A Active CN106925438B (en) | 2017-03-29 | 2017-03-29 | Small-capacity plasma separation cup based on ultrasonic welding technology |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108144142A (en) * | 2018-01-18 | 2018-06-12 | 董亚东 | A kind of centrifugal type blood composition separate cup and separation method |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2000102603A (en) * | 1999-11-04 | 2000-04-11 | Toshiyuki Tanabe | Centrifugal bowl |
CN2397492Y (en) * | 1999-11-02 | 2000-09-20 | 吴强 | Disposable blood component separating cup |
US20010027156A1 (en) * | 1999-06-03 | 2001-10-04 | Yair Egozy | Core for blood processing apparatus |
WO2014071365A1 (en) * | 2012-11-05 | 2014-05-08 | Haemonetics Corporation | Continuous flow separation chamber |
CN204293591U (en) * | 2014-12-02 | 2015-04-29 | 四川南格尔生物科技有限公司 | A kind of low capacity Blood calldack separate cup |
CN206631782U (en) * | 2017-03-29 | 2017-11-14 | 艾沃生物科技(苏州)有限公司 | A kind of low capacity blood plasma separate cup based on ultra-sonic welding techniques |
-
2017
- 2017-03-29 CN CN201710196204.0A patent/CN106925438B/en active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20010027156A1 (en) * | 1999-06-03 | 2001-10-04 | Yair Egozy | Core for blood processing apparatus |
CN2397492Y (en) * | 1999-11-02 | 2000-09-20 | 吴强 | Disposable blood component separating cup |
JP2000102603A (en) * | 1999-11-04 | 2000-04-11 | Toshiyuki Tanabe | Centrifugal bowl |
WO2014071365A1 (en) * | 2012-11-05 | 2014-05-08 | Haemonetics Corporation | Continuous flow separation chamber |
CN204293591U (en) * | 2014-12-02 | 2015-04-29 | 四川南格尔生物科技有限公司 | A kind of low capacity Blood calldack separate cup |
CN206631782U (en) * | 2017-03-29 | 2017-11-14 | 艾沃生物科技(苏州)有限公司 | A kind of low capacity blood plasma separate cup based on ultra-sonic welding techniques |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108144142A (en) * | 2018-01-18 | 2018-06-12 | 董亚东 | A kind of centrifugal type blood composition separate cup and separation method |
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CN106925438B (en) | 2023-12-15 |
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