CN205839002U - cell filter - Google Patents

cell filter Download PDF

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Publication number
CN205839002U
CN205839002U CN201620806591.6U CN201620806591U CN205839002U CN 205839002 U CN205839002 U CN 205839002U CN 201620806591 U CN201620806591 U CN 201620806591U CN 205839002 U CN205839002 U CN 205839002U
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CN
China
Prior art keywords
filter
communicating pipe
ring skeleton
cell
annular sidewall
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Application number
CN201620806591.6U
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Chinese (zh)
Inventor
汪铮
吴振化
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Translated Description Zhejiang Biological Technology Co Ltd
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Translated Description Zhejiang Biological Technology Co Ltd
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Application filed by Translated Description Zhejiang Biological Technology Co Ltd filed Critical Translated Description Zhejiang Biological Technology Co Ltd
Priority to CN201620806591.6U priority Critical patent/CN205839002U/en
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Abstract

The utility model discloses a kind of cell filter, this cell filter includes that annular sidewall, the bottom of described annular sidewall are sealed by end drainage screen, forms filter chamber between described annular sidewall and end drainage screen;The rising wood of described annular sidewall is circumferentially with ring skeleton, and the lower surface of described ring skeleton is provided with the elastic seal ring for closing itself and centrifuge tube junction;Being inserted with the breather for connecting centrifuge tube and external environment on described ring skeleton, described breather is provided with keying valve, has the effect reducing cell contamination.

Description

Cell filter
Technical field
This utility model relates to cell extraction field, particularly to a kind of cell filter.
Background technology
In cell (especially stem cell) is treated, due to the wind of the cell mass existence blocking blood vessel that multiple cells form Danger, so being typically infused in the patient with the form of individual cells.For removing intracellular impurity such as connective tissue, typically need To carry out cell filtering purification processes.Cell filter, is a kind of common cell filtration equipment for purifying, and cell can be trained by it Foster base filters, and separates acquisition cell.
The Chinese patent that Authorization Notice No. is CN203569111U, authorized announcement date is on April 30th, 2014 discloses one Planting the centrifuge tube of band cell filter, its cell filter includes framework and filter membrane, and framework includes top anchor ring, bottom annulus Connected by middle brace rod between face and middle brace rod, and described top anchor ring and bottom anchor ring;Filter membrane includes the end Portion's filter membrane and exterior annular filter membrane, the lower surface of the excircle part of bottom filter membrane is supported on the inner top side face of bottom anchor ring, The upper surface of the excircle part of bottom filter membrane connects exterior annular filter membrane, and exterior annular filter membrane is close to what middle brace rod was surrounded Ring surface;The upper surface of centrifuge tube is close in the lower surface of the top anchor ring under cell filtration state, and top anchor ring evagination has Pinch and take boss, pinch and take boss and expose to the outer ring surface of described body.
In the operating process that cell filtration separates, the pressure meeting carrier (such as centrifuge tube) and external environment is needed to keep base This is consistent, and the mode that prior art employing carrier and cell filter are not closed is to solve this technical problem.But this side In formula, there is certain cross-ventilation in external environment and carrier, there is the risk of contamination of cells.
Utility model content
The purpose of this utility model is to provide a kind of cell filter, which solves asking of cell contamination in separation process Topic, has the effect reducing cell contamination.
Above-mentioned technical purpose of the present utility model has the technical scheme that
A kind of cell filter, including annular sidewall, the bottom of described annular sidewall is sealed by end drainage screen, described ring Filter chamber is formed between shape sidewall and end drainage screen;The rising wood of described annular sidewall is circumferentially with ring skeleton, described annular The lower surface of skeleton is provided with the elastic seal ring for closing itself and centrifuge tube junction;It is inserted with use on described ring skeleton In connection centrifuge tube and the breather of external environment, described breather is provided with keying valve.
Use said structure, during use, cell filter is placed on centrifuge tube, ring skeleton and the upper end of centrifuge tube Abut and played by elastic seal ring between the two the effect of sealing;Then carried out in Cell sap is placed on filter chamber Filter, Cell sap enters centrifuge tube through end drainage screen, can open and close valve by regulation and regulate external environment and centrifuge tube in filter process Between pressure so that filter be smoothed out, have reduce cell contamination effect.
More preferably: described breather includes the interior communicating pipe for connecting centrifuge tube and external environment, be set in Outer communicating pipe outside communicating pipe, described keying valve was located on outer communicating pipe;Described outer communicating pipe is located on ring skeleton away from mistake The interior gas outlet away from filter chamber and described outer communicating pipe it is located on ring skeleton on the side of filter chamber, and described interior communicating pipe Outer gas outlet is not disposed on same straight line.
Use said structure, increase the gas in external environment and enter the path of centrifuge tube, reduce the inside and outside direct convection current of gas Probability, even if the gas that also can reduce when pressure regulation is strong in external environment enters the probability of centrifuge tube, improve thin further Born of the same parents' separation purity.
More preferably: be fixed with rubber tube on described outer gas outlet, in described rubber tube, be provided with ball;Described rubber The diameter of pipe is gradually reduced on the direction away from outer gas outlet from outer gas outlet, and the diameter of ball is between the maximum of rubber tube Between diameter and minimum diameter.
Use said structure, increase external environment gas and enter the difficulty of centrifuge tube, reduce the gas in external environment enter from The probability of heart pipe, improves cell separation purity further.
More preferably: described annular sidewall is formed by connecting by spaced side drainage screen and collateral dagger.
Use said structure, strengthen the face that may filter that, improve and filter purification efficiency.
More preferably: described filter chamber is inverted cone.
Use said structure, narrow under filter chamber, impulse force during filtration can be increased, accelerate filter efficiency;Filter chamber simultaneously Bottom and centrifuge tube between relative to point open, convenient observe filtering phenomenon.
More preferably: the side of described ring skeleton is provided with takes boss.
Use said structure, easy disassembly cell filter, reduce the residuals on cell filter to operator Impact.
In sum, this utility model has the advantages that
1, filter process valve, the ball position in rubber tube be can open and close by regulation and external environment and centrifuge tube regulated Between pressure so that filter be smoothed out;
2, in filter process, the upper end of ring skeleton and centrifuge tube is abutted and is played by elastic seal ring close between the two The effect of envelope, reduces impurity and pollutes;In gas centrifuge tube to be entered in external environment, need the rubber tube through carrying ball, outer Communicating pipe and interior communicating pipe, and outer gas outlet and interior gas outlet be not provided with on the same line, the distance passed through is relatively long and road Journey is the most tortuous, can reduce the gas in external environment and enter the probability of centrifuge tube;Improve cell separation purity further.
Accompanying drawing explanation
Fig. 1 is the perspective view of embodiment;
Fig. 2 is the plan structure schematic diagram of embodiment;
Fig. 3 is the A-A schematic diagram of Fig. 2.
In figure, 1, annular sidewall;11, side drainage screen;12, collateral dagger;2, end drainage screen;3, filter chamber;4, annular bone Frame;5, boss is taken;6, elastic seal ring;7, breather;71, interior communicating pipe;72, outer communicating pipe;73, rubber tube;8, open and close Valve;9, ball.
Detailed description of the invention
Below in conjunction with accompanying drawing, this utility model is described in further detail.
This specific embodiment is only that it is not to restriction of the present utility model, ability to explanation of the present utility model The present embodiment can be made after reading this specification by field technique personnel as required does not has the amendment of creative contribution, but As long as all being protected by Patent Law in right of the present utility model.
Embodiment: cell filter, as Figure 1-3.With reference to Fig. 1, this cell filter includes annular sidewall 1, its end Portion is sealed by end drainage screen 2.Annular sidewall 1 is in inverted cone, and it is by spaced side drainage screen 11 and collateral dagger 12 It is formed by connecting.Filter chamber 3 is formed between annular sidewall 1 and end drainage screen 2.
With reference to Fig. 1, the rising wood of annular sidewall 1 is circumferentially with ring skeleton 4, the side of ring skeleton 4 be provided with take convex Platform 5.The lower surface of ring skeleton 4 is provided with the elastic seal ring 6 for closing itself and centrifuge tube junction.
In conjunction with Fig. 2 and Fig. 3, ring skeleton 4 is inserted with interior communicating pipe 71, interior communicating pipe 71 and the connection of ring skeleton 4 Locate the most sealed process.The interior air inlet of interior communicating pipe 71 is located at the top of centrifuge tube, during in it, gas outlet is located at external environment.Ring On shape skeleton 4, the side away from filter chamber 3 is provided with outer communicating pipe 72, is set in the outer and outer connection of interior communicating pipe 71 outer communicating pipe 72 Pipe 72 and the most sealed process in junction of ring skeleton 4.Outer gas outlet on outer communicating pipe 72 and going out in interior communicating pipe 71 QI KOU is not provided with on the same line, and is provided with the keying valve 8 for regulating outer gas outlet gas output outer communicating pipe 72.
With reference to Fig. 3, outer gas outlet is fixed with rubber tube 73, in rubber tube 73, is provided with ball 9.From outer gas outlet to away from On the direction of outer gas outlet, the diameter of rubber tube 73 is gradually reduced.The diameter of ball 9 is between the maximum gauge and of rubber tube 73 Between minor diameter.Interior communicating pipe 71, outer communicating pipe 72 and rubber tube 73 constitute breather 7.
During use, being placed on centrifuge tube by cell filter, the upper end of ring skeleton 4 and centrifuge tube abuts and both it Between play the effect of sealing by elastic seal ring 6;Then filter in Cell sap is placed on filter chamber 3, Cell sap warp End drainage screen 2 and side drainage screen 11 enter centrifuge tube, can open and close valve 8, ball 9 in rubber tube 73 by regulation in filter process Position regulate the pressure between external environment and centrifuge tube so that filter be smoothed out, and in filter process reduce pollute.

Claims (6)

1. a cell filter, it is characterised in that include annular sidewall (1), end mistake is passed through in the bottom of described annular sidewall (1) Filter screen (2) seals, and forms filter chamber (3) between described annular sidewall (1) and end drainage screen (2);Described annular sidewall (1) upper Edge is circumferentially with ring skeleton (4), and the lower surface of described ring skeleton (4) is provided with for closing itself and centrifuge tube junction Elastic seal ring (6);The breather (7) for connecting centrifuge tube and external environment it is inserted with on described ring skeleton (4), described Breather (7) is provided with keying valve (8).
Cell filter the most according to claim 1, it is characterised in that described breather (7) includes for connecting centrifugal Managing the interior communicating pipe (71) with external environment, be set in interior communicating pipe (71) outer communicating pipe (72) outward, described keying valve (8) is located at On outer communicating pipe (72);Described outer communicating pipe (72) is located at the side on ring skeleton (4) away from filter chamber (3), and described interior It is located on communicating pipe (71) on ring skeleton (4) away from the interior gas outlet of filter chamber (3) and going out of described outer communicating pipe (72) QI KOU is not provided with on the same line.
Cell filter the most according to claim 2, it is characterised in that be fixed with rubber tube on described outer gas outlet (73), it is provided with ball (9) in described rubber tube (73);The diameter of described rubber tube (73) from outer gas outlet to away from outer gas outlet Direction on be gradually reduced, and the diameter of ball (9) is between maximum gauge and the minimum diameter of rubber tube (73).
Cell filter the most according to claim 1, it is characterised in that described annular sidewall (1) is by spaced side Drainage screen (11) and collateral dagger (12) are formed by connecting.
Cell filter the most according to claim 1, it is characterised in that described filter chamber (3) is in inverted cone.
Cell filter the most according to claim 1, it is characterised in that the side of described ring skeleton (4) is provided with takes Boss (5).
CN201620806591.6U 2016-07-27 2016-07-27 cell filter Active CN205839002U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201620806591.6U CN205839002U (en) 2016-07-27 2016-07-27 cell filter

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201620806591.6U CN205839002U (en) 2016-07-27 2016-07-27 cell filter

Publications (1)

Publication Number Publication Date
CN205839002U true CN205839002U (en) 2016-12-28

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201620806591.6U Active CN205839002U (en) 2016-07-27 2016-07-27 cell filter

Country Status (1)

Country Link
CN (1) CN205839002U (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111004715A (en) * 2019-12-30 2020-04-14 安徽惠恩生物科技股份有限公司 Stem cell collection device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111004715A (en) * 2019-12-30 2020-04-14 安徽惠恩生物科技股份有限公司 Stem cell collection device
CN111004715B (en) * 2019-12-30 2023-05-05 安徽国祯生物科技有限公司 Stem cell collection system

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