CN106915135A - 新型低密度药品包装复合膜及其制备方法 - Google Patents

新型低密度药品包装复合膜及其制备方法 Download PDF

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CN106915135A
CN106915135A CN201710128606.7A CN201710128606A CN106915135A CN 106915135 A CN106915135 A CN 106915135A CN 201710128606 A CN201710128606 A CN 201710128606A CN 106915135 A CN106915135 A CN 106915135A
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layer
composite membrane
pharmaceutical packaging
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packaging composite
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许荣芳
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Wuxi City Yang Jianhuaqiang Plastic Colourprinting Co Ltd
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Wuxi City Yang Jianhuaqiang Plastic Colourprinting Co Ltd
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/32—Layered products comprising a layer of synthetic resin comprising polyolefins
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B15/00—Layered products comprising a layer of metal
    • B32B15/04—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • B32B15/08—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
    • B32B15/088—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin comprising polyamides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B15/00—Layered products comprising a layer of metal
    • B32B15/20—Layered products comprising a layer of metal comprising aluminium or copper
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • B32B27/08—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/12—Layered products comprising a layer of synthetic resin next to a fibrous or filamentary layer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/34—Layered products comprising a layer of synthetic resin comprising polyamides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B7/00—Layered products characterised by the relation between layers; Layered products characterised by the relative orientation of features between layers, or by the relative values of a measurable parameter between layers, i.e. products comprising layers having different physical, chemical or physicochemical properties; Layered products characterised by the interconnection of layers
    • B32B7/04—Interconnection of layers
    • B32B7/10—Interconnection of layers at least one layer having inter-reactive properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D65/00—Wrappers or flexible covers; Packaging materials of special type or form
    • B65D65/38—Packaging materials of special type or form
    • B65D65/40—Applications of laminates for particular packaging purposes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2262/00—Composition or structural features of fibres which form a fibrous or filamentary layer or are present as additives
    • B32B2262/06—Vegetal fibres
    • B32B2262/062—Cellulose fibres, e.g. cotton
    • B32B2262/065—Lignocellulosic fibres, e.g. jute, sisal, hemp, flax, bamboo
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/30—Properties of the layers or laminate having particular thermal properties
    • B32B2307/306—Resistant to heat
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/50—Properties of the layers or laminate having particular mechanical properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/50—Properties of the layers or laminate having particular mechanical properties
    • B32B2307/552—Fatigue strength
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/50—Properties of the layers or laminate having particular mechanical properties
    • B32B2307/554—Wear resistance
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/50—Properties of the layers or laminate having particular mechanical properties
    • B32B2307/582—Tearability
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2439/00—Containers; Receptacles
    • B32B2439/80—Medical packaging

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Abstract

一种低密度药品包装复合膜，以聚乙烯为基膜，在聚乙烯基膜的上表层粘结一层亚麻纤维层，在聚乙烯基膜的下表层粘结双向拉伸尼龙层即BOPA；在双向拉伸尼龙层的表面涂覆一层固体胶，在固体胶的表面粘结有铝箔。本发明复合膜具有非吸附性能，能阻止药品中有效物活性成分的迁移；同时，也阻碍药物活性成分对粘合层的破坏，防止内层的脱层，极大程度上保护内包装物的阻隔性能，最大限度的防止内包装物因受潮、迁移发生质变、降低药效。

Description

新型低密度药品包装复合膜及其制备方法
技术领域
本发明涉及医药包装材料技术领域，尤其是涉及一种新型低密度药品包装复合膜及其制备方法。
背景技术
药用包装材料将直接影响用药的安全性，不同的内容物对包装材料的要求各不相同。有许多药品要求遮光、阻水、阻氧，成型性好，特别是有些药物要求易撕开。许多定向性的材料生产的复合膜虽然在其他方面表现出优良的性能，在此方面却显得不足。低密度药品包装复合膜具有良好的阻隔性、热封性、走机性、柔软性等，更具有其他复合材料不具备的易撕性。
发明内容
针对现有技术存在的上述问题，本申请提供了一种新型低密度药品包装复合膜及其制备方法。本发明复合膜具有非吸附性能，能阻止药品中有效物活性成分的迁移；同时，也阻碍药物活性成分对粘合层的破坏，防止内层的脱层，极大程度上保护内包装物的阻隔性能，最大限度的防止内包装物因受潮、迁移发生质变、降低药效。
本发明的技术方案如下：
一种低密度药品包装复合膜，以聚乙烯为基膜，在聚乙烯基膜的上表层粘结一层亚麻纤维层，在聚乙烯基膜的下表层粘结双向拉伸尼龙层即BOPA；在双向拉伸尼龙层的表面涂覆一层固体胶，在固体胶的表面粘结有铝箔。
所述聚乙烯基膜的厚度为0.3～0.5mm。所述亚麻纤维的厚度为0.1～0.15mm。
所述双向拉伸尼龙层的厚度为0.08～0.12mm。优选的，所述双向拉伸尼龙层的厚度为0.1mm。
所述铝箔和固体胶的厚度之和为0.08～0.12mm。优选的，所述铝箔和固体胶的厚度之和为0.1mm。
优选的，粘结铝箔时采用铝箔卷抓取装置，通过调节顶杆的位置，可以适应多种不同内径的卷芯。在制备复合膜的过程中采用包装卷膜的自动传送装置，采用齿轮啮合传动。
本发明有益的技术效果在于：
本发明以聚乙烯作为基膜，保证产品的阻隔性能。采用具有耐高温、高强度、耐老化、耐摩擦的适合印刷的亚麻纤维材料作为印刷表层材料，能够持久的保持完好的外观及印刷图案。
本发明采用非吸附性能的双向拉伸尼龙和铝箔热封层材料，阻止药品中有效药物活性成分的迁移，同时防止内层的脱层，极大程度上保护内包装物的阻隔性能。
本发明生成过程中采用铝箔卷的抓取装置，结构简单，维护方便，能够有效的保护手，避免受到伤害。通过调节顶杆的位置，可以适应多种不同内径的卷芯。
本发明在制备过程中采用包装卷膜的自动传送装置，采用齿轮啮合传动，移动平稳，可以适应不同高度，可以更安全的支撑包装卷膜，且可支持多种直径的卷芯。
本发明技术处于领先水平，采用多层材料复合而成，层次分明、美观耐压、复合附着力大、不起泡、不破裂、剥离强度大、热封性能好，不但具有高阻隔性和优良的印刷适性，而且具有良好的易撕性，柔韧性适中，使用方便安全，同时先进制备工艺的研究和应用，极大提升了产品的生成效率和成品合格率，因此本发明的市场前景十分广阔。
本发明对保证我国医疗药品安全具有重要的现实意义。同时能够带动我国医疗行业的发展，对促进药品包装材料的产业升级起到积极的作用。
具体实施方式
下面结合实施例，对本发明进行具体描述。
实施例1
本发明提供的低密度药品包装复合膜，以聚乙烯为基膜，在聚乙烯基膜的上表层粘结一层亚麻纤维层，在聚乙烯基膜的下表层粘结双向拉伸尼龙层即BOPA；在双向拉伸尼龙层的表面涂覆一层固体胶，在固体胶的表面粘结有铝箔。
所述聚乙烯基膜的厚度为0.3mm。所述亚麻纤维的厚度为0.1mm。所述双向拉伸尼龙层的厚度为0.08mm。所述铝箔和固体胶的厚度之和为0.08mm。
在粘结铝箔时采用铝箔卷抓取装置，通过调节顶杆的位置，可以适应多种不同内径的卷芯。在制备复合膜的过程中采用包装卷膜的自动传送装置，采用齿轮啮合传动。
实施例2
本发明提供的低密度药品包装复合膜，以聚乙烯为基膜，在聚乙烯基膜的上表层粘结一层亚麻纤维层，在聚乙烯基膜的下表层粘结双向拉伸尼龙层即BOPA；在双向拉伸尼龙层的表面涂覆一层固体胶，在固体胶的表面粘结有铝箔。
所述聚乙烯基膜的厚度为0.5mm。所述亚麻纤维的厚度为0.15mm。所述双向拉伸尼龙层的厚度为0.12mm。所述铝箔和固体胶的厚度之和为0.12mm。
在粘结铝箔时采用铝箔卷抓取装置，通过调节顶杆的位置，可以适应多种不同内径的卷芯。在制备复合膜的过程中采用包装卷膜的自动传送装置，采用齿轮啮合传动。
实施例3
本发明提供的低密度药品包装复合膜，以聚乙烯为基膜，在聚乙烯基膜的上表层粘结一层亚麻纤维层，在聚乙烯基膜的下表层粘结双向拉伸尼龙层即BOPA；在双向拉伸尼龙层的表面涂覆一层固体胶，在固体胶的表面粘结有铝箔。
所述聚乙烯基膜的厚度为0.4mm。所述亚麻纤维的厚度为0.12mm。所述双向拉伸尼龙层的厚度为0.1mm。所述铝箔和固体胶的厚度之和为0.1mm。
在粘结铝箔时采用铝箔卷抓取装置，通过调节顶杆的位置，可以适应多种不同内径的卷芯。在制备复合膜的过程中采用包装卷膜的自动传送装置，采用齿轮啮合传动。
检测例：
将实施例制备得到的复合膜进行性能测试，其红外光谱：PET\LDPE层与对照图谱完全一致；无异常毒性。

Claims (9)

1.一种低密度药品包装复合膜，其特征在于以聚乙烯为基膜，在聚乙烯基膜的上表层粘结一层亚麻纤维层，在聚乙烯基膜的下表层粘结双向拉伸尼龙层即BOPA；在双向拉伸尼龙层的表面涂覆一层固体胶，在固体胶的表面粘结有铝箔。
2.根据权利要求1所述的低密度药品包装复合膜，其特征在于所述聚乙烯基膜的厚度为0.3～0.5mm。
3.根据权利要求1所述的低密度药品包装复合膜，其特征在于所述亚麻纤维的厚度为0.1～0.15mm。
4.根据权利要求1所述的低密度药品包装复合膜，其特征在于所述双向拉伸尼龙层的厚度为0.08～0.12mm。
5.根据权利要求1所述的低密度药品包装复合膜，其特征在于所述双向拉伸尼龙层的厚度为0.1mm。
6.根据权利要求1所述的低密度药品包装复合膜，其特征在于所述铝箔和固体胶的厚度之和为0.08～0.12mm。
7.根据权利要求1所述的低密度药品包装复合膜，其特征在于所述铝箔和固体胶的厚度之和为0.1mm。
8.根据权利要求1所述的低密度药品包装复合膜，其特征在于粘结铝箔时采用铝箔卷抓取装置，通过调节顶杆的位置，可以适应多种不同内径的卷芯。
9.根据权利要求1所述的低密度药品包装复合膜，其特征在于在制备复合膜的过程中采用包装卷膜的自动传送装置，采用齿轮啮合传动。
CN201710128606.7A 2017-03-06 2017-03-06 新型低密度药品包装复合膜及其制备方法 Pending CN106915135A (zh)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN203126049U (zh) * 2013-03-27 2013-08-14 许荣芳 低密度聚乙烯药品包装用复合膜
CN203529538U (zh) * 2013-11-15 2014-04-09 无锡市羊尖华强塑料彩印有限公司 铝箔卷的抓取装置
CN203567309U (zh) * 2013-11-25 2014-04-30 宁波龙安包装科技有限公司 药用栓剂复合膜
CN203567280U (zh) * 2013-11-25 2014-04-30 宁波龙安包装科技有限公司 栓剂复合膜

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN203126049U (zh) * 2013-03-27 2013-08-14 许荣芳 低密度聚乙烯药品包装用复合膜
CN203529538U (zh) * 2013-11-15 2014-04-09 无锡市羊尖华强塑料彩印有限公司 铝箔卷的抓取装置
CN203567309U (zh) * 2013-11-25 2014-04-30 宁波龙安包装科技有限公司 药用栓剂复合膜
CN203567280U (zh) * 2013-11-25 2014-04-30 宁波龙安包装科技有限公司 栓剂复合膜

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Application publication date: 20170704