CN106913722A - 一种茯苓枸杞子治疗老年哮喘症的中药颗粒冲剂 - Google Patents

一种茯苓枸杞子治疗老年哮喘症的中药颗粒冲剂 Download PDF

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CN106913722A
CN106913722A CN201510997208.XA CN201510997208A CN106913722A CN 106913722 A CN106913722 A CN 106913722A CN 201510997208 A CN201510997208 A CN 201510997208A CN 106913722 A CN106913722 A CN 106913722A
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刘海燕
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Abstract

本发明公开了一种茯苓枸杞子治疗老年哮喘症的中药颗粒冲剂，其中药组分是由茯苓15%～17%、枸杞子10%～12%、熟地6%～8%、丹皮6%～8%、泽泻6%～8%、怀枸杞子6%～8%、五味子6%～8%、山萸肉6%～8%、补骨脂10%～12%、巴戟天10%～12%、胡桃肉8%～10%组成；经浸提、浓缩干燥、制软材、制粒、干燥、整粒、灭菌包装的步骤，制备出茯苓枸杞子治老年人哮喘症的中药颗粒冲剂，具有滋补肝肾、定神安志之功效；可以有效地缓解和消除老年人哮喘症及老年人哮喘症引起的各类症状，且疗效显著，见效快，疗程短，无副作用。

Description

一种茯苓枸杞子治疗老年哮喘症的中药颗粒冲剂
技术领域
本发明涉及中药的技术领域，尤指一种茯苓枸杞子治疗老年哮喘症的中药颗粒冲剂。
背景技术
哮喘是因气管和支气管对各种刺激物的刺激不能适应，而引起的支气管平滑肌痉挛、黏膜肿胀、分泌物增加，从而导致支气管管腔狭窄。喘症以呼吸困难，甚至张口抬肩、鼻翼煽动、不能平卧为特征；哮症是一种发作性的痰鸣气喘疾患，发作时喉中哮鸣有声、呼吸困难，甚则喘息难以平卧。由于哮必兼喘，故又称作哮喘，哮喘包括支气管哮喘、哮喘性支气管炎等。
支气管哮喘(bronchial asthma)是由多种细胞特别是肥大细胞、嗜酸性粒细胞和T淋巴细胞参与的慢性气道炎症，在易感者中此种炎症可引起反复发作的喘息，气促、胸闷和(或)咳嗽等症状，多在夜间和(或)凌晨发生，气道对多种刺激因子反应性增高。但症状可自行或经治疗缓解。近十余年来，美国、英国、澳大利亚，新西兰等国家哮喘患病率和死亡率有上升趋势，全世界约有一亿哮喘患者，已成为严重威胁公众健康的一种主要慢性疾病，我国哮喘的患病率约为1%，儿童可达3%，据测算全国约有1千万以上哮喘患者。
发明内容
本发明一种茯苓枸杞子治疗老年哮喘症的中药颗粒冲剂，可以解决上述技术的不足，采用茯苓和枸杞子辅以熟地、丹皮、泽泻、怀枸杞子、五味子、山萸肉、补骨脂、巴戟天、胡桃肉11味中药，经浸提、浓缩干燥、制软材、制粒、干燥、整粒、灭菌包装的步骤制备出颗粒冲剂，实现中药颗粒冲剂快速治疗老年哮喘症之目的。
为了实现上述目的，本发明的技术解决方案是：一种茯苓枸杞子治疗老年哮喘症的中药颗粒冲剂的中药组分：茯苓15%～17%、枸杞子10%～12%、熟地6%～8%、丹皮6%～8%、泽泻6%～8%、怀枸杞子6%～8%、五味子6%～8%、山萸肉6%～8%、补骨脂10%～12%、巴戟天10%～12%、胡桃肉8%～10%。
制备步骤如下：
⑴浸提：将中药组分除杂、粉碎，置入夹层浸提罐中，温度70℃～80℃加10倍量水，浸提5h，取浸提液存放；再加8倍量水，温度70℃～80℃浸提3h，合并两次煎煮液，用100目筛过滤；
⑵浓缩干燥：滤液置入真空浓缩罐内，设定真空度97kPa、温度55℃～70℃，浓缩成浓缩液，浓缩液为中药组分的25%，再将浓缩液经过喷雾干燥，得浸提粉；
⑶制软材：浸提粉30%加入捏合机中，再加入蔗糖粉10%、糊精10%、干淀粉50%，用含量50%的乙醇调制为软材药坨；
⑷制粒：采用颗粒机制造出湿状颗粒；
⑸干燥：将湿状颗粒置入60℃的气流干燥机内脱水干燥；
⑹整粒：将干燥后的颗粒再过1次10目筛整粒，得颗粒冲剂；
⑺灭菌包装：将颗粒冲剂置入紫外线下照射2～3min后每袋10g包装。
本发明各种组份的药性及作用：
茯苓：具有味甘、淡、性平，入药具有利水渗湿、益脾和胃、宁心安神之功用。现代医学研究：茯苓能增强机体免疫功能，茯苓多糖有明显的抗肿瘤及保肝脏的作用；
枸杞子：具有滋补肝肾，益精明目；用于虚劳精亏，腰膝酸痛，眩晕耳鸣，内热消渴，血虚萎黄，目昏不明症状的功效；
熟地：具有滋阴补血，益精填髓。用于肝肾阴虚，腰膝酸软，骨蒸潮热，盗汗遗精，内热消渴，血虚萎黄，心悸怔忡，月经不调，崩漏下血，眩晕，耳鸣，须发早白的功效；
丹皮：具有清热凉血；活血散瘀。温热病热入血分；发斑；吐衄；热病后期热伏阴分发热；阴虚骨蒸潮热；血滞经闭；痛经；痈肿疮毒；跌扑伤痛；风湿热痹的功效；
泽泻：具有利水，渗湿，泄热；治小便不利，水肿胀满，呕吐，泻痢，痰饮，脚气，淋病，尿血症状的功效；
怀山药：具有补益肝肾；收敛固脱；主腰头晕目眩；耳聋耳鸣；腰膝酸软；跹精滑精；小便频数；虚汗不止；妇女崩漏；内热消渴；温肝补肾，除一切风，止月经过多，治老人尿频功效；
五味子：具有敛肺，滋肾，生津，收汗，涩精；治肺虚喘咳，口干作渴，自汗，盗汗，劳伤羸瘦，梦遗滑精，久泻久痢等症状的功效；
山萸肉：具有补益肝肾，涩精固脱。用于眩晕耳鸣，腰膝酸痛，阳痿遗精，遗尿尿频，崩漏带下，大汗虚脱。内热消渴等症状的功效。
补骨脂：具有温肾助阳，纳气，止泻；用于阳痿遗精，遗尿尿频，腰膝冷痛，肾虚作喘，五更泄泻；外用治白癜风，斑秃等症状的功效。
巴戟天：具有补肾阳，强筋骨，祛风湿；可以补肾阳，益精血，强筋骨，祛风湿；治疗肾阳虚弱的阳痿，不孕，月经不调，少腹冷痛等症状的功效。
胡桃肉：具有补肾固精，温肺定喘，润肠，治肾虚喘嗽，腰痛脚弱，阳痿，遗精，小便频数，石淋，大便燥结等症状的功效。
本发明服药方法：当患有老年人哮喘的患者，每天服用3袋，1袋10克；于早中晚饭后1个半小时后开水冲服，1月为1个疗程；可以有效地缓解和消除老年人哮喘症及老年人哮喘症引起的各类症状，具有滋补肝肾、定神安志之功效；且疗效显著，见效快，疗程短，无副作用。
具体实施方式
实施例1
中药组分：茯苓15%、枸杞子10%、熟地7%、丹皮8%、泽泻8%、怀山药8%、五味子7%、山萸肉7%、补骨脂10%、巴戟天10%、胡桃肉10%。
⑵制备步骤如下：
①浸提：将中药组分除杂、粉碎，置入夹层浸提罐中，温度70℃～80℃加10倍量水，浸提5h，取浸提液存放；再加8倍量水，温度70℃～80℃浸提3h，合并两次煎煮液，用100目筛过滤；
②浓缩干燥：滤液置入真空浓缩罐内，设定真空度97kPa、温度55℃～70℃，浓缩成浓缩液，浓缩液为中药组分的25%，再将浓缩液经过喷雾干燥，得浸提粉；
③制软材：浸提粉20%加入捏合机中，再加入蔗糖粉、糊精，用含量50%的乙醇调制为软材药坨；
④制粒：采用颗粒机制造出湿状颗粒；
⑤干燥：将湿状颗粒置入60℃气流干燥机内脱水干燥；
⑥整粒：将干燥后的颗粒再过1次10目筛整粒，得颗粒冲剂；
⑦灭菌包装：将颗粒冲剂置入紫外线下照射2～3min后每袋10g包装。
实施例2
中药组分：茯苓16%、枸杞子11%、熟地8%、丹皮7%、泽泻6%、怀山药6%、五味子8%、山萸肉8%、补骨脂11%、巴戟天11%、胡桃肉8%。
⑵制备步骤如下：
①浸提：将中药组分除杂、粉碎，置入夹层浸提罐中，温度70℃～80℃加10倍量水，浸提5h，取浸提液存放；再加8倍量水，温度70℃～80℃浸提3h，合并两次煎煮液，用100目筛过滤；
②浓缩干燥：滤液置入真空浓缩罐内，设定真空度97kPa、温度55℃～70℃，浓缩成浓缩液，浓缩液为中药组分的25%，再将浓缩液经过喷雾干燥，得浸提粉；
③制软材：浸提粉20%加入捏合机中，再加入蔗糖粉、糊精，用含量50%的乙醇调制为软材药坨；
④制粒：采用颗粒机制造出湿状颗粒；
⑤干燥：将湿状颗粒置入60℃气流干燥机内脱水干燥；
⑥整粒：将干燥后的颗粒再过1次10目筛整粒，得颗粒冲剂；
⑦灭菌包装：将颗粒冲剂置入紫外线下照射2～3min后每袋10g包装。
实施例3
中药组分：茯苓17%、枸杞子12%、熟地6%、丹皮6%、泽泻7%、怀山药7%、五味子6%、山萸肉6%、补骨脂12%、巴戟天12%、胡桃肉9%。
⑵制备步骤如下：
①浸提：将中药组分除杂、粉碎，置入夹层浸提罐中，温度70℃～80℃加10倍量水，浸提5h，取浸提液存放；再加8倍量水，温度70℃～80℃浸提3h，合并两次煎煮液，用100目筛过滤；
②浓缩干燥：滤液置入真空浓缩罐内，设定真空度97kPa、温度55℃～70℃，浓缩成浓缩液，浓缩液为中药组分的25%，再将浓缩液经过喷雾干燥，得浸提粉；
③制软材：浸提粉20%加入捏合机中，再加入蔗糖粉、糊精，用含量50%的乙醇调制为软材药坨；
④制粒：采用颗粒机制造出湿状颗粒；
⑤干燥：将湿状颗粒置入60℃气流干燥机内脱水干燥；
⑥整粒：将干燥后的颗粒再过1次10目筛整粒，得颗粒冲剂；
⑦灭菌包装：将颗粒冲剂置入紫外线下照射2～3min后每袋10g包装。
以上所述，实施方式仅仅是对本发明的优选实施方式进行描述，并非对本发明的范围进行限定，在不脱离本发明技术的精神的前提下，本领域工程技术人员对本发明的技术方案作出的各种变形和改进，均应落入本发明的权利要求书确定的保护范围内。

Claims (1)

1.一种茯苓枸杞子治疗老年哮喘症的中药颗粒冲剂，其特征是：所述的茯苓枸杞子治疗老年哮喘症的中药颗粒冲剂中药组分为：茯苓15%～17%、枸杞子10%～12%、熟地6%～8%、丹皮6%～8%、泽泻6%～8%、怀枸杞子6%～8%、五味子6%～8%、山萸肉6%～8%、补骨脂10%～12%、巴戟天10%～12%、胡桃肉8%～10%。
CN201510997208.XA 2015-12-28 2015-12-28 一种茯苓枸杞子治疗老年哮喘症的中药颗粒冲剂 Pending CN106913722A (zh)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110496182A (zh) * 2019-09-11 2019-11-26 王兆建 一种基于补肾阳的哮喘药及其制备方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110496182A (zh) * 2019-09-11 2019-11-26 王兆建 一种基于补肾阳的哮喘药及其制备方法

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