CN106907875B - Centralized cooling system of freeze dryer - Google Patents
Centralized cooling system of freeze dryer Download PDFInfo
- Publication number
- CN106907875B CN106907875B CN201510971542.8A CN201510971542A CN106907875B CN 106907875 B CN106907875 B CN 106907875B CN 201510971542 A CN201510971542 A CN 201510971542A CN 106907875 B CN106907875 B CN 106907875B
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- storage tank
- temperature storage
- low
- normal
- freeze
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Classifications
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25B—REFRIGERATION MACHINES, PLANTS OR SYSTEMS; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS
- F25B1/00—Compression machines, plants or systems with non-reversible cycle
- F25B1/10—Compression machines, plants or systems with non-reversible cycle with multi-stage compression
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25B—REFRIGERATION MACHINES, PLANTS OR SYSTEMS; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS
- F25B43/00—Arrangements for separating or purifying gases or liquids; Arrangements for vaporising the residuum of liquid refrigerant, e.g. by heat
- F25B43/006—Accumulators
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25B—REFRIGERATION MACHINES, PLANTS OR SYSTEMS; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS
- F25B43/00—Arrangements for separating or purifying gases or liquids; Arrangements for vaporising the residuum of liquid refrigerant, e.g. by heat
- F25B43/04—Arrangements for separating or purifying gases or liquids; Arrangements for vaporising the residuum of liquid refrigerant, e.g. by heat for withdrawing non-condensible gases
- F25B43/043—Arrangements for separating or purifying gases or liquids; Arrangements for vaporising the residuum of liquid refrigerant, e.g. by heat for withdrawing non-condensible gases for compression type systems
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
- F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25B—REFRIGERATION MACHINES, PLANTS OR SYSTEMS; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS
- F25B2313/00—Compression machines, plants or systems with reversible cycle not otherwise provided for
- F25B2313/001—Compression machines, plants or systems with reversible cycle not otherwise provided for with two or more accumulators
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- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Power Engineering (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Drying Of Solid Materials (AREA)
Abstract
The invention discloses a concentrated cooling system of a freeze dryer, which comprises a freeze dryer, a condenser, a normal-temperature storage tank, a low-temperature storage tank and a compressor unit. The freeze-drying box is directly connected with the condenser, the normal temperature storage tank and the low temperature storage tank are respectively connected with the freeze-drying box and the condenser through pipelines, the compressor unit comprises a plurality of compressors, and the compressor unit is respectively connected with the normal temperature storage tank and the low temperature storage tank. The centralized cooling system of the freeze dryer adopts a structure with two storage tanks, and can optimize the refrigerating effect of the freeze dryer.
Description
Technical Field
The present invention relates to a cooling system, and more particularly, to a centralized cooling system for a freeze dryer.
Background
Lyophilization is a method of obtaining a dry aqueous substance by freezing the aqueous substance into a solid by cooling in advance and then sublimating the water from the solid into water vapor in a vacuum state. The sublimated water vapor is captured in the cold trap, and defrosting is performed after the freeze-drying is finished. Because the natural defrosting time is longer, and the production requirements of pharmaceutical factories cannot be met, most pharmaceutical enterprises adopt the method that steam is introduced into a condenser to defrost.
The temperature in the cold trap of the freeze dryer of the medical equipment is as low as minus 60 ℃, and the freeze dryer is completed by doing work by a compressor. The compressor is usually turned on for a long time to maintain a cold trap low temperature environment, and the energy consumption is high. The temperature difference between the cold trap and the oven is in turn closely related to the rate at which the drug is dried. The temperature of the drying oven is limited by the pharmaceutical process, so the lower the temperature in the cold trap, the faster the drug drying rate.
However, the main disadvantage of freeze drying technology is the high cost, and because it requires vacuum and cryogenic conditions, a set of vacuum and cryogenic systems is deployed, and thus the investment and operating costs are relatively high.
The refrigeration system is the core of the freeze dryer and is also the most important point of energy consumption. Several important performance indicators are associated with the freeze dryer, one of which is the rate of cooling. Because of the difference between peaks and valleys of industrial electricity, under the condition of a plurality of freeze-drying machines, a refrigerating system for intensively cooling is designed based on the consideration of reducing energy consumption and improving cooling rate.
After the medicines are filled into the box, the medicines are generally required to be cooled to the prefreezing temperature required by the medicine technology as soon as possible, and after sterilization, the temperature of the plate layer is required to be reduced. The 2 processes, according to the traditional method, generally take more than half an hour.
Disclosure of Invention
Aiming at the problem of low refrigeration efficiency of a freeze dryer in the prior art, the invention aims to provide a concentrated cooling system of the freeze dryer.
In order to achieve the above purpose, the invention adopts the following technical scheme:
a concentrated cooling system of a freeze dryer comprises a freeze drying box, a condenser, a normal-temperature storage tank, a low-temperature storage tank and a compressor unit. The freeze-drying box is directly connected with the condenser, the normal temperature storage tank and the low temperature storage tank are respectively connected with the freeze-drying box and the condenser through pipelines, the compressor unit comprises a plurality of compressors, and the compressor unit is respectively connected with the normal temperature storage tank and the low temperature storage tank.
According to an embodiment of the present invention, the compressor unit is connected to the normal temperature storage tank and the low temperature storage tank through the first circulation pump.
According to one embodiment of the invention, the normal temperature storage tank and the low temperature storage tank are communicated through a valve.
According to an embodiment of the invention, the inlet of the freeze-drying box is sequentially provided with a second circulating pump and a heater.
According to an embodiment of the invention, the second circulation pump is connected to the cryogenic tank and the condenser, respectively.
In the technical scheme, the centralized cooling system of the freeze dryer adopts a structure with two storage tanks, so that the refrigerating effect of the freeze dryer can be optimized.
Drawings
Fig. 1 is a schematic structural view of a centralized cooling system of the freeze dryer of the present invention.
Detailed Description
The technical scheme of the invention is further described below with reference to the accompanying drawings and examples.
Referring to fig. 1, the invention discloses a concentrated cooling system of a freeze dryer, which mainly comprises a freeze dryer 1, a condenser 2, a compressor unit 3, a low-temperature storage tank 4, a normal-temperature storage tank 5, a heater 6, a second circulating pump 7, a first circulating pump 8, a valve 9 and the like. The connection relation and the function of each of the above structures will be described in detail.
As shown in fig. 1, the freeze-drying tank 1 is directly connected with the condenser 2, and a second circulation pump 7 and a heater 6 are sequentially provided at an inlet of the freeze-drying tank 1, the second circulation pump 7 being connected to the cryogenic tank 4 and the condenser 2, respectively. The normal temperature storage tank 5 and the low temperature storage tank 4 are respectively connected with the freeze-drying box 1 and the condenser 2 through pipelines, the compressor unit 3 comprises a plurality of compressors, and the compressor unit 3 is respectively connected with the normal temperature storage tank 5 and the low temperature storage tank 4. The normal temperature storage tank 5 and the low temperature storage tank 4 are communicated with each other through a valve 9, and the compressor unit 3 is connected to the normal temperature storage tank 5 and the low temperature storage tank 4 through a first circulation pump 8.
The structure of the invention adopts a double-storage tank structure, namely a normal-temperature storage tank 5 and a low-temperature storage tank 4, and can realize rapid cooling through direct replacement of cold and hot silicone oil. The two liquid storage tanks respectively store low-temperature silicone oil and normal-temperature silicone oil, and the low-temperature storage tank 4 can keep continuous refrigeration in production, so that the cold quantity of production can be maintained sufficiently. The silicone oil in the normal temperature storage tank 5 can be cooled to the same temperature as the low temperature storage tank 4 through cold mixing refrigeration in the electricity consumption low peak period and is supplemented into the low temperature storage tank 4, so that the effect of reducing energy consumption is achieved.
As shown in fig. 1, all compressors can be started to refrigerate the silicone oil in the cold tank when electricity is used in a valley, and meanwhile, the valve 9 is intermittently opened and closed to refrigerate the silicone oil in the normal-temperature storage tank 5 through tragic cooling, so that the silicone oil in the normal-temperature storage tank 5 is led into the cold tank. There are 2 first circulation pumps 8, one of which is designed as redundancy, and the other is started when one of them fails.
During the rapid cooling process, the silicone oil in the pipeline to be replaced is controlled by the second circulating pump 7. In the process of maintaining the refrigerating capacity of the freeze dryer in normal operation, the temperature of the rear box is maintained below-60 ℃ by the second circulating pump 7.
It will be appreciated by persons skilled in the art that the above embodiments are provided for illustration only and not for limitation of the invention, and that variations and modifications of the above described embodiments are intended to fall within the scope of the claims of the invention as long as they fall within the true spirit of the invention.
Claims (1)
1. A concentrated cooling system for a freeze dryer, comprising:
the device comprises a freeze-drying box, a condenser, a normal-temperature storage tank, a low-temperature storage tank and a compressor unit;
the freeze-drying box is directly connected with the condenser, and the normal temperature storage tank and the low temperature storage tank are respectively connected with the freeze-drying box and the condenser through pipelines;
the compressor unit comprises a plurality of compressors, and is respectively connected with the normal temperature storage tank and the low temperature storage tank,
the compressor unit is connected to the normal temperature storage tank and the low temperature storage tank through a first circulating pump,
a second circulating pump and a heater are sequentially arranged at the inlet of the freeze-drying box,
the second circulation pump is respectively connected to the cryogenic storage tank and the condenser,
the normal temperature storage tank is communicated with the low temperature storage tank through a valve,
the low-temperature storage tank and the normal-temperature storage tank respectively store low-temperature silicone oil and normal-temperature silicone oil, the silicone oil in the normal-temperature storage tank is cooled to the same temperature as the low-temperature storage tank through cold doping refrigeration in the low-peak period of electricity consumption and is supplemented into the low-temperature storage tank, thereby playing a role in reducing energy consumption,
through tragic cooling, the valve is opened and closed intermittently to refrigerate the silicone oil in the normal temperature storage tank, and the silicone oil in the normal temperature storage tank is led into the cold tank.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510971542.8A CN106907875B (en) | 2015-12-22 | 2015-12-22 | Centralized cooling system of freeze dryer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510971542.8A CN106907875B (en) | 2015-12-22 | 2015-12-22 | Centralized cooling system of freeze dryer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106907875A CN106907875A (en) | 2017-06-30 |
| CN106907875B true CN106907875B (en) | 2023-07-25 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510971542.8A Active CN106907875B (en) | 2015-12-22 | 2015-12-22 | Centralized cooling system of freeze dryer |
Country Status (1)
| Country | Link |
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| CN (1) | CN106907875B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110131969A (en) * | 2019-05-30 | 2019-08-16 | 琅沃(上海)机械设备有限公司 | A kind of parallel multi-joint freeze-drying system |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201488475U (en) * | 2009-09-23 | 2010-05-26 | 上海共和真空技术有限公司 | Condenser system for freezedryer |
| CN103759457A (en) * | 2013-12-10 | 2014-04-30 | 重庆翔源制冷设备有限公司 | Effective cold-storage type less-ammonia refrigeration system of ammonia refrigerator |
| CN204630218U (en) * | 2015-03-11 | 2015-09-09 | 福州龙福食品有限公司 | A kind of sharp freezing room refrigeration structure |
-
2015
- 2015-12-22 CN CN201510971542.8A patent/CN106907875B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201488475U (en) * | 2009-09-23 | 2010-05-26 | 上海共和真空技术有限公司 | Condenser system for freezedryer |
| CN103759457A (en) * | 2013-12-10 | 2014-04-30 | 重庆翔源制冷设备有限公司 | Effective cold-storage type less-ammonia refrigeration system of ammonia refrigerator |
| CN204630218U (en) * | 2015-03-11 | 2015-09-09 | 福州龙福食品有限公司 | A kind of sharp freezing room refrigeration structure |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106907875A (en) | 2017-06-30 |
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