CN106890185A - 具有短半衰期的选择性雌激素受体调节剂及其用途 - Google Patents
具有短半衰期的选择性雌激素受体调节剂及其用途 Download PDFInfo
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Landscapes
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- Orthopedic Medicine & Surgery (AREA)
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- Pregnancy & Childbirth (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| Application Number | Priority Date | Filing Date | Title |
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| US201261598723P | 2012-02-14 | 2012-02-14 | |
| US61/598723 | 2012-02-14 | ||
| CN201380009176.7A CN104114162A (zh) | 2012-02-14 | 2013-02-14 | 具有短半衰期的选择性雌激素受体调节剂及其用途 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN106890185A true CN106890185A (zh) | 2017-06-27 |
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| CN201380009176.7A Pending CN104114162A (zh) | 2012-02-14 | 2013-02-14 | 具有短半衰期的选择性雌激素受体调节剂及其用途 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN201380009176.7A Pending CN104114162A (zh) | 2012-02-14 | 2013-02-14 | 具有短半衰期的选择性雌激素受体调节剂及其用途 |
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| EP (2) | EP2814471A1 (enExample) |
| JP (1) | JP2015506988A (enExample) |
| CN (2) | CN106890185A (enExample) |
| AU (1) | AU2013221478B2 (enExample) |
| CA (1) | CA2864104A1 (enExample) |
| HK (1) | HK1203155A1 (enExample) |
| MX (1) | MX2014009154A (enExample) |
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| US20160038506A1 (en) * | 2012-02-14 | 2016-02-11 | Repros Therapeutics Inc. | Selective Estrogen Receptor Modulators With Short Half-Lives and Uses Thereof |
| US9744177B2 (en) | 2014-03-10 | 2017-08-29 | Endorecherche, Inc. | Treatment of male androgen deficiency symptoms or diseases with sex steroid precursor combined with SERM |
| CA2989364C (en) | 2016-04-22 | 2021-07-20 | F.I.S. - Fabbrica Italiana Sintetici S.P.A. | Process for the preparation of enclomiphene citrate having needle shaped crystal habit. |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1108101A (zh) * | 1993-12-21 | 1995-09-13 | 伊莱利利公司 | 抑制男性不育症的方法 |
| CN101163467A (zh) * | 2005-03-22 | 2008-04-16 | 雷普罗斯治疗公司 | 反式氯米芬给药方案 |
| WO2010054248A1 (en) * | 2008-11-07 | 2010-05-14 | Repros Therapeutics Inc. | Trans-clomiphene for metabolic syndrome and diabetes mellitus type 2 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4133814A (en) | 1975-10-28 | 1979-01-09 | Eli Lilly And Company | 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents |
| DE3046719C2 (de) | 1980-12-11 | 1983-02-17 | Klinge Pharma GmbH, 8000 München | 1,1,2-Triphenyl-but-1-en-Derivate, Verfahren zu ihrer Herstellung und Arzneimittel |
| US4418068A (en) | 1981-04-03 | 1983-11-29 | Eli Lilly And Company | Antiestrogenic and antiandrugenic benzothiophenes |
| US4447622A (en) | 1981-09-22 | 1984-05-08 | Council Of Scientific And Industrial Research Rafi Marg | Preparation of l- and d-isomers of dl-3,4-trans-2,2-disubstituted-3,4-diarylchromans and derivatives thereof |
| US5510357A (en) | 1995-02-28 | 1996-04-23 | Eli Lilly And Company | Benzothiophene compounds as anti-estrogenic agents |
| IL120262A (en) * | 1996-02-28 | 2001-01-28 | Pfizer | Droloxifene and derivatives thereof for use in increasing serum testosterone levels |
| US5998402A (en) | 1996-04-19 | 1999-12-07 | American Home Products Corporation | 2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indoles as estrogenic agents |
| US6479535B1 (en) | 1998-05-15 | 2002-11-12 | Wyeth | 2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indole and estrogen formulations |
| NZ534348A (en) * | 2000-01-28 | 2006-06-30 | Endorech Inc | Selective estrogen receptor modulators in combination with estrogens |
| US7135575B2 (en) * | 2003-03-03 | 2006-11-14 | Array Biopharma, Inc. | P38 inhibitors and methods of use thereof |
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2013
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- 2013-02-14 JP JP2014556834A patent/JP2015506988A/ja active Pending
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1108101A (zh) * | 1993-12-21 | 1995-09-13 | 伊莱利利公司 | 抑制男性不育症的方法 |
| CN101163467A (zh) * | 2005-03-22 | 2008-04-16 | 雷普罗斯治疗公司 | 反式氯米芬给药方案 |
| WO2010054248A1 (en) * | 2008-11-07 | 2010-05-14 | Repros Therapeutics Inc. | Trans-clomiphene for metabolic syndrome and diabetes mellitus type 2 |
Also Published As
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| EP3300725A2 (en) | 2018-04-04 |
| HK1203155A1 (en) | 2015-10-23 |
| US20150031680A1 (en) | 2015-01-29 |
| WO2013123218A1 (en) | 2013-08-22 |
| JP2015506988A (ja) | 2015-03-05 |
| MX2014009154A (es) | 2014-08-27 |
| US9161940B2 (en) | 2015-10-20 |
| EP2814471A1 (en) | 2014-12-24 |
| EP3300725A3 (en) | 2018-05-16 |
| CN104114162A (zh) | 2014-10-22 |
| AU2013221478A1 (en) | 2014-08-14 |
| AU2013221478B2 (en) | 2017-06-01 |
| CA2864104A1 (en) | 2013-08-22 |
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