CN106880045A - Application of the honey matrimony vine tomato juice in strengthen immunity health food is prepared - Google Patents
Application of the honey matrimony vine tomato juice in strengthen immunity health food is prepared Download PDFInfo
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- CN106880045A CN106880045A CN201510928132.5A CN201510928132A CN106880045A CN 106880045 A CN106880045 A CN 106880045A CN 201510928132 A CN201510928132 A CN 201510928132A CN 106880045 A CN106880045 A CN 106880045A
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- matrimony vine
- honey
- tomato juice
- strengthen immunity
- health food
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/02—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation containing fruit or vegetable juices
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses application of the honey matrimony vine tomato juice in strengthen immunity health food is prepared.The present invention is had found by function test research, it is 47.7g-190.8g that honey matrimony vine tomato juice eats dosage daily in people, can suppress delayed allergy mice ear degree, raise lymphocyte proliferation activity and NK cytoactives, improve mouse phagocytic index and and carbonic clearance ability and improve half hemolytic dose, show that honey matrimony vine tomato juice has the function of strengthen immunity, can be used in preparing strengthen immunity health food.
Description
Technical field
The present invention relates to application of the honey matrimony vine tomato juice in health food, more particularly in strengthen immunity health care work(
Application in energy.
Background technology
Immune is a kind of important protectiveness physiological function of human body, and hypoimmunity is easily caused the reduction of vitality, life
The health problem such as go down of reason function and adaptability, is mainly shown as and easily feel tired, easy catching a cold, easily infects etc..Research
It has been shown that, hypoimmunity and inferior health have it is important associate, be to cause one of major reason of inferior health, sub-health state is same
Also easily there is immunosuppressant phenomenon in sample.A global sex inventory according to WHO is bright, and the people in the whole world 75% is in inferior health
Situation.Sub-health state prevalence rate is between 17.8%~60.5% in China's country's population, and sub-health state prevalence rate
Increase with the age and raise, the elderly's prevalence rate has exceeded 90%.Therefore, by strengthen immunity, improvement people's inferior health is reached
The effect of state.As environment deteriorates increasingly, people's life stress is growing on and on, and social competition is growing more intense, strengthen immunity,
Improve sub-health state, the ideal chose in people's life will be increasingly becomed.
Tomato is that nutritionist unanimously generally acknowledges the food of vegetal pole horn of plenty, wherein both including protein, fat, carbon aquation
The nutritional ingredients such as compound, also contain the mineral matter such as the multivitamin such as vitamin B1, B2, C, P and potassium, calcium, phosphorus, iron.In tomato
Also contain a kind of lycopene with important physiological function, be one kind of carotenoid, with certain inoxidizability, quilt
Western countries are referred to as " plant gold ".Matrimony vine is improved the effect of immunity of organisms, can with improving eyesight, tonifying Qi it is strong it is smart, nourishing liver and kidney,
Anti-aging, only quench one's thirst, warming up body, antitumor, three high drop effect.Honey is a kind of natural sweet taste food of medicine-food two-purpose, is contained
There are various naturals such as phenolic compound, VC, carotenoid, amino acid and antioxidase, with antibacterial, anti-inflammatory, control
Treat and scald various functions such as burn and children cough.
Number of patent application：201510099339.6 disclose a kind of honey matrimony vine tomato juice and preparation method thereof, by weight
The concentrated tomato paste 20% ~ 30% of percentage, honey 6% ~ 12%, matrimony vine 2 ~ 8%, the component composition of water 55% ~ 72%.The product has
Source is natural, the content of lycopene is high, ingredients Biogenic availability is high, and have concurrently tomato medlar and honey three it is natural flavour mountaineous,
The good to eat advantage of sweet mouthfeel, it is very popular.
However, at present, application of the honey matrimony vine tomato juice in strengthen immunity health food has no document report.
The content of the invention
It is an object of the invention to provide application of the honey matrimony vine tomato juice in strengthen immunity health food is prepared.
Goal of the invention of the invention is achieved by the following technical solution：
Application of the honey matrimony vine tomato juice in strengthen immunity health food is prepared.
Wherein, the honey matrimony vine tomato juice is consisted of the following components in percentage by weight：Concentrated tomato paste 20% ~ 30%,
Honey 6% ~ 12%, matrimony vine 2 ~ 8%, water 55% ~ 72%.
The preparation method of the honey matrimony vine tomato juice refers to Chinese Patent Application No.：201510099339.6, specific bag
Include following steps：
Step one, Baoshang：The matrimony vine of formula ratio is added in the water of formula ratio carries out Baoshang, obtains Chinese wolfberry soup；
Step 2, filtering：The Chinese wolfberry soup that step one is obtained is filtered, soup slag is removed, the pure soup of matrimony vine is obtained；
Step 3, mixing：The concentrated tomato paste and honey of formula ratio are added to the pure soup of matrimony vine obtained in step 2, after mixing
To compound；
Step 4, homogeneous：The compound that step 3 is obtained carries out homogeneous, obtains the compound after homogeneous；
Step 5, advance heat-sterilization：Compound after step 4 homogeneous is carried out into advance heat-sterilization at 80 DEG C ~ 90 DEG C, that is, obtains honeybee
Sweet matrimony vine tomato juice.
Wherein, the dosage edible daily of the honey matrimony vine tomato juice is 47.7g-190.8g.
The usage of the honey matrimony vine tomato juice is taken directly to take or washing by water, daily edible 1-3 times.
Strengthen immunity of the present invention increases to suppress delayed allergy mice ear degree, raising lymphocyte
Activity and NK cytoactives are grown, mouse phagocytic index and carbonic clearance ability is improved and improves half hemolytic dose.
Health food of the present invention is plant beverage, Juice, fruit, vegetable juice or jelly.
Tomato（Lycopersicon esculentumMil.l）It is the vegetable crop of global plantation extensively, master contained therein
It is lycopene etc. to want functional component, and Lycopene in Tomatoes content has certain difference with kind is different, and wherein content is high
Up to 8.86mg/100g, average content is up to 4.88 mg/100g.Lycopene (lycopene) be distributed in animals and plants it is very wide
A Carotenoids, can promote cellular immunity and humoral immune function, strengthen immunity of organisms, the effect and its antioxygen
Change function closely related.
Phenolic acid class contained by honey and flavones ingredient can make the quantity increase of antibody secreting cell and strengthen humoral immunity
Function.
The main active of matrimony vine is then polysaccharide, with functions such as immunological regulations.
The present invention uses honey, matrimony vine and tomato prescription, combines different carotenoid, phenolic acid class, flavonoids and many
The composition of the strengthen immunity of carbohydrate, each composition can play assistance strengthen immunity effect, with larger functionality advantage.
The present invention through pharmacological research find, honey matrimony vine tomato juice can suppress delayed allergy mice ear degree,
Lymphocyte proliferation activity and NK cytoactives can significantly be raised, significantly improve mouse phagocytic index and and carbonic clearance ability and
Half hemolytic dose is significantly improved, shows that honey matrimony vine tomato juice has the healthcare function of strengthen immunity, can be used in system
Standby strengthen immunity health food.
Specific embodiment：
Honey matrimony vine tomato juice used by the embodiment of the present invention is beneficial board honey matrimony vine tomato juice forever, by Dongguan Yong Yi food companies
Production.
Wherein, honey matrimony vine tomato juice, including following weight raw material：
The kg of concentrated tomato paste 20, the kg of honey 6, the kg of matrimony vine 2, the kg of water 55.
In the present embodiment, the concentration of concentrated tomato paste is 29%.
The preparation method of above-mentioned honey matrimony vine tomato juice is as follows：
Step one, Baoshang：The matrimony vine of formula ratio is added to carries out Baoshang, first boiled with big fire, Ran Houyong in the water of formula ratio
Line fire pot obtains Chinese wolfberry soup in 3 hours；
Step 2, filtering：The Chinese wolfberry soup that step one is obtained is filtered, soup slag is removed, the pure soup of matrimony vine is obtained；
Step 3, mixing：The concentrated tomato paste and honey of formula ratio are added to the pure soup of matrimony vine obtained in step 2, after mixing
To compound；
Step 4, homogeneous：The compound that step 3 is obtained carries out homogeneous, obtains the compound after homogeneous；
Step 5, advance heat-sterilization：Compound after step 4 homogeneous is carried out into advance heat-sterilization at 90 DEG C, that is, obtains honey matrimony vine
Tomato juice.
Embodiment 1：Delayed allergy is tested.
Purpose：Honey tomato etc. is evaluated in observation to be influenceed by test product on mice ear degree and swelling inhibiting rate.
Dose design：The clinical adult's consumption per day of honey tomato juice is 95.4g, reference《Herbal pharmacology research methodology》Middle dose
Amount conversion method " body surface area ratio " conversion mice clinical dose,equivalent is 12.402 gkg-1, using this dosage as rat
Middle dose group.High dose is the twice of middle dosage, i.e. 24.804 gkg-1, low dosage is the half of middle dosage, i.e., 6.201
g·kg-1。
Honey tomato medlar juice, clinic adult's consumption per day is 95.4g, reference《Herbal pharmacology research methodology》Middle dosage is changed
Calculation method " body surface area ratio " conversion mice clinical dose,equivalent is 12.402 gkg-1, using this dosage as the middle agent of rat
Amount group.High dose is the twice of middle dosage, i.e. 24.804 gkg-1, low dosage is the half of middle dosage, i.e. 6.201 gkg-1。
Packet and administration：After mouse conventinal breeding 3 days, 7 groups are randomly divided into, every group 10, respectively blank control group, kind
Lycopene soft capsule group, the high, medium and low dosage group of honey tomato, the high, medium and low dosage group of honey tomato medlar.Start after packet to
Medicine, once a day, continuous 30d, gavage amount is 0.2 mL/10g, and blank control group gives isometric distilled water.
Method of sensitization：Every mouse skin of abdomen of each group barium sulphide loses hair or feathers, and scope about 3 cm × 3cm, uses DNFB solution
50 μ L uniform application sensitization.After 5 d, with the μ L uniform applications of DNFB solution 10 in mouse right ear（Two sides）Attacked.Attack
24 h cervical dislocations put to death mouse afterwards, cut left and right auricular concha, and the auricle of the mm of diameter 8 is removed with card punch, weigh.Ear swelling degree
（mg）=auris dextra weight-left ear weight.
Swelling inhibiting rate is calculated according to below equation：The ear swelling inhibiting rate=[(average swelling-administration of blank control group
The average swelling of group) the average swelling of/blank control group] × 100%.
Experiment statisticses method：All measurement datas add and subtract standard deviation with mean（）Represent.The multigroup comparing of mean
Using one-way analysis of variance（One-Way ANOVA）, mean compares two-by-two between group, and LSD methods are used when variance is neat；Heterogeneity of variance
Shi Caiyong Dunnett ' s T3 methods.Completed by SPSS l7.0 softwares.
Experimental result is shown in Table 1.
The each group mice ear degree of table 1（, n=10）
（Note：Compared with blank control group, * P<0.05）
As seen from the results in Table 1, compared with blank control group, the swelling of honey tomato medlar low dose group is remarkably decreased, and declines
Degree is less than honey tomato juice, it is therefore intended that honey tomato medlar juice has than honey tomato juice preferably suppresses allergy mouse
The function of ear swelling rate.
Embodiment 2：Lymphopoiesis and NK cytoactives are tested
Experiment purpose：Investigate influence of the sample to lymphocyte function and NK cytoactives.
Experimental technique：The clinical adult's consumption per day of honey tomato juice is 95.4g, reference《Herbal pharmacology research methodology》Middle dose
Amount conversion method " body surface area ratio " conversion mice clinical dose,equivalent is 12.402 gkg-1, using this dosage as rat
Middle dose group.High dose is the twice of middle dosage, i.e. 24.804 gkg-1, low dosage is the half of middle dosage, i.e., 6.201
g·kg-1。
The clinical adult's consumption per day of honey matrimony vine tomato juice is 95.4g, reference《Herbal pharmacology research methodology》Middle dosage is changed
Calculation method " body surface area ratio " conversion mice clinical dose,equivalent is 12.402 gkg-1, using this dosage as the middle agent of rat
Amount group.High dose is the twice of middle dosage, i.e. 24.804 gkg-1, low dosage is the half of middle dosage, i.e. 6.201 gkg-1。
Packet and administration NIH mouse, male, body weight 18-22g are divided into 7 groups, every group 10, all mouse conventinal breedings 3
After it, start administration, the medicine of corresponding dosage is given respectively, once a day, continuous 30d, Normal group gives isometric(al) distillation
Water.
Preparation of reagents complete culture solution RPMI1640 nutrient solution filtration sterilizations, with 10% hyclone of preceding addition, mould
Element（100 U/ml）, streptomysin（100 μg//L）, pH to 7.0- is adjusted with the NaOH of the HCl or 1mol/L of aseptic 1mol/L
7.2, i.e. complete culture solution.ConA liquid：The solution of 100 μ g/ml, filtration sterilization, in low temperature refrigerator are configured to distilled water（-20
℃）Preserve.Aseptic Hank's liquid：With preceding with 3.5% aseptic NaHCO3Adjust pH7.2-7.4.
Be dissolved in 5 mg MTT in the PBS of 1 ml pH7.2 by MTT liquid, now with the current.
The HCl of 4 ml 1mol/L, prepared before use are added in acid isopropyl alcoholic solution 96ml isopropanols.
Splenocyte suspension is aseptic to take spleen, is placed in filling appropriate aseptic Hank's liquid plate, is gently ground spleen with tweezers
It is broken, it is made individual cells suspension.Through 200 mesh sieve net filtrations, or spleen is ground with 4 layers of gauze, wash 2 times with Hank's liquid, every time
10 min are centrifuged（1000 r/min）.Then cell is suspended in the complete culture solution of 1ml, is lived with platform phenol orchid dyeing counting thin
Born of the same parents' number（Should be more than 95%）, adjustment cell concentration is 3 × 106Individual/ml.
Lymphproliferation response adds cell suspension point holes in 24 well culture plates, and per the mL of hole 1, a hole adds 75 μ
L ConA liquid（Equivalent to 7.5 ug/ml）（a）, another hole is used as control（b）, put 5%CO2, 37 DEG C of CO2In cell culture incubator
Cultivate 72 h.Culture terminates preceding 4 h, and the ml of supernatant 0.7 is gently sucked per hole, adds RPMIs of 0.7 ml without calf serum
RPMI-1640, while adding MTT（5 mg/ml）50 μ l/hole, continue to cultivate 4 h, after culture terminates, 1ml acid are added per hole
Property isopropanol, piping and druming mix, be completely dissolved purple crystal, be then dispensed into 96 well culture plates, each hole dispense 3 hole conducts
Duplicate Samples, with enzyme-linked immunosorbent assay instrument, the absorbance of solution are determined with 570 nm wavelength（OD）, calculate proliferation activity（Propagation
Activity=ODa-ODb）.
The preparation of LDH matrix liquids
Lithium lactate 5 × 10-2mol/L
Nitro tetrazolium chloride（INT） 6.6×10-4mol/L
PMS（PMS） 2.8×10-4mol/L
Oxidized coenzyme I（NAD） 1.3×10-3
Mentioned reagent is dissolved in the Tris-HCl buffer solutions of 0.2 mol/L（pH8.2）
The passage of target cell（YAC-1 cells）Target cell is carried out Secondary Culture by 24h before experiment, and 3 are washed with Hank's liquid using preceding
Secondary, it is 4 × 10 to adjust cell concentration with RPMI1640 complete culture solutions5Individual/ml.
The preparation of splenocyte suspension（Effector cell）It is aseptic to take spleen, it is placed in the small plate for filling appropriate aseptic Hank's liquid
In, gently spleen is ground with tweezers, it is made single cell suspension.Through 200 mesh sieve net filtrations, or spleen is ground with 4 layers of gauze, or used
Hank's liquid is washed 2 times, every time 10 min of centrifugation（1000 r/min）, abandon supernatant and cytoplasm is upspring, add 0.5 ml aqua sterilisas
20 seconds, 0.5 ml, 2 times of Hank ' s liquid and 8 mL Hank ' s liquid are added after splitting erythrocyte, 1000 rpm, 10 min are centrifuged,
It is resuspended with RPMI1640 complete culture solutions of the 1ml containing 10% calf serum, counted after being diluted with 1% glacial acetic acid（Viable count should be
More than 95%）, with platform phenol orchid dyeing counting viable count（Should be more than 95%）, finally adjust thin with RPMI1640 complete culture solutions
Born of the same parents' concentration is 2 × 107Individual/ml.
NK cytoactive detections take target cell and each 100 μ l of effector cell（Effect target compares 50:1）, add U-shaped 96 hole culture
In plate；Target cell Spontaneous release hole adds target cell and each 100 μ l of nutrient solution, and target cell maximum release aperture adds target cell and 1%
Each 100 μ l of NP40 or 2.5%Triton；Above-mentioned items are all provided with three multiple holes, in 37 DEG C, 5%CO24 h are cultivated in incubator, so
96 well culture plates are centrifuged 5 min with 1500 r/min afterwards, per hole in the well culture plate of 100 μ l horizontalizations bottom of absorption supernatant 96, while
The μ l of LDH matrix liquids 100 are added, 3 min are reacted, the μ l of HCl 30 of 1 mol/L are added per hole, determined at the nm of ELIASA 490
Absorbance（OD）.
NK cytoactives are calculated as follows, the NK cytoactives of test sample group are significantly higher than the NK cells work of control group
Property, you can judge this experimental result positive.
Experiment statisticses method：
All measurement datas add and subtract standard deviation with mean（）Represent.The multigroup comparing of mean is using single factor test variance point
Analysis（One-Way ANOVA）, mean compares two-by-two between group, and LSD methods are used when variance is neat；Dunnett ' s are used during heterogeneity of variance
T3 methods.Completed by SPSS l7.0 softwares.
Experimental result is shown in Table 2.
The each group mouse lymphocyte proliferation activity of table 2 and NK cytoactives（, n=10）
（Note：Compared with Normal group, #P<0.05）
As seen from the results in Table 2, compared with Normal group, honey matrimony vine tomato juice lymphocyte proliferation activity and NK cytoactives
There is significantly rising, and positive findings is presented.
Embodiment 3：Mouse carbon particle clearance test
Experiment purpose observation evaluates honey tomato etc. by test product to mouse liver index and the shadow of spleen index and carbonic clearance ability
Ring.
The high, medium and low dosage of dose design honey tomato juice is respectively 24.804 gkg-1、12.402 g·kg-1With
6.201 g·kg-1。
The high, medium and low dosage of honey matrimony vine tomato juice is respectively 24.804 gkg-1、12.402 g·kg-1With 6.201
g·kg-1。
Packet and administration, test mice conventinal breeding are randomly divided into 7 groups, respectively every group 10, blank after 3 days
Group, the high, medium and low dosage group of honey tomato, the high, medium and low dosage group of honey matrimony vine tomato.
Start administration after packet, once a day, continuous 30d, gavage amount is 0.2 mL/10g, and blank control group such as gives at the body
Product distilled water.
Modeling method claims Mouse Weight, from the india ink of tail vein injection dilution, based on every mL of 10 g body weight 0.1
Calculate.Treat that prepared Chinese ink injects, timing immediately.2 min after injection prepared Chinese ink（t1）, 10 min（t2）, take blood 20 from angular vein clump respectively
UL, the existing side by side Na of 2 mL 0.1% of be added into2CO3In solution.With multi-functional readout instrument at 600 nm wavelength densitometric value
（OD）, with Na2CO3Solution makees blank.By sacrifice, liver and spleen are taken, organ surface blood stains are blotted with filter paper, claimed
Weigh and calculate liver index and spleen index.Liver index and spleen index are respectively the ratio of liver or spleen weight/body weight.Referred to swallowing
Number represents mouse carbonic clearance ability, is calculated as follows phagocytic index a.Given the test agent phagocytic index is significantly higher than the phagocytosis of control group
Index, can determine that this experimental result is the positive.Formula is：
The all measurement datas of experiment statisticses method add and subtract standard deviation with mean（）Represent, the multigroup comparing of mean is used
One-way analysis of variance（One-Way ANOVA）, mean compares two-by-two between group, and LSD methods are used when variance is neat；Adopted during heterogeneity of variance
With Dunnett ' s T3 methods.Completed by SPSS l7.0 softwares.
Experimental result is shown in Table 3.
Honey tomato of table 3 etc. is influenceed by test product on mouse phagocytic index（, n=10）
（Note：Compared with Normal group, #P<0.05）
By table:Knowable to 3 results, compared with blank control group, respectively improved by the mouse phagocytic index of test product group, its
In middle honey matrimony vine tomato juice, low dose group there is significant difference, compared with not plus matrimony vine sample effect it is more preferable.
Embodiment 4：The measure of humoral immune function measure-serum hemolysin
Experiment purpose investigates the half hemolytic value HC50 of each group sample.
The high, medium and low dosage of dose design honey tomato juice is respectively 24.804 gkg-1、12.402 g·kg-1With
6.201 g·kg-1。
The high, medium and low dosage of honey matrimony vine tomato juice is respectively 24.804 gkg-1、12.402 g·kg-1With 6.201
g·kg-1。
All mouse conventinal breedings are grouped and be administered after 3 days, 7 groups, respectively every group 10, blank are randomly divided into
Group, soft capsule of lycopene group, the high, medium and low dosage group of honey tomato, the high, medium and low dosage group of honey matrimony vine tomato.After packet
Start administration, once a day, continuous 30d, gavage amount is 0.2 mL/10g, and blank control group gives isometric distilled water.
The preparation sheep taking blood from jugular vein of sheep red blood cell (SRBC) SRBC and complement, sheep blood is placed with the sterilizing cone of bead
Shaken in one direction in shape bottle, to take off fiber, it is standby to be put into 4 DEG C of Refrigerator stores, can preserve 2 weeks.Collection guinea pig blood, isolates
Serum（At least 5 pooled serums of cavy）, 1 mL hematocrits SRBC is added in 5 ml GPSs, put 4 DEG C of refrigerators 30
Min, often vibration, centrifuging and taking supernatant, packing, -80 DEG C of preservations.Used time is with SA liquid by 1: 8 dilution.
Immune animal and serum are separated and take sheep blood, with brine 3 times, every time from (2000 r/min) 10
min.Hematocrit SRBC physiological saline is made into 2%（v/v）Cell suspension, every mouse intraperitoneal injection 0.2mL is immunized.4
After it, extract eyeball and take blood in centrifuge tube, place about 1h, serum is fully separated out, 2000r/min centrifugation 10min collect blood
Clearly.
Hemolytic reaction takes serum SA buffer solutions and dilutes 200 times.Serum 1ml after dilution is put in test tube, is added successively
Enter 10% (v/v) SRBC 0.5 ml, complement 1ml（1 is pressed with SA liquid:8 dilutions）.The another control tube for setting not increase serum（With SA liquid
Instead of）.Put after being incubated 15~30 min in 37 DEG C of waters bath with thermostatic control, ice bath terminating reaction.2000 r/min are centrifuged 10 min.Take
The ml of clear liquid 1, plus the ml of Dou Shi reagents 3, while taking the ml of 10% (v/v) SRBC 0.25 adds Dou Shi reagents to 4ml, fully mix,
After placing 10 min, sentence control tube in 540 nm and make blank, each pipe OD value is determined respectively.The amount of hemolysin is molten with half
Blood value（HC50）Represent, calculated by following equation：
The all measurement datas of experiment statisticses method add and subtract standard deviation with mean（）Represent.The multigroup comparing of mean is used
One-way analysis of variance（One-Way ANOVA）, mean compares two-by-two between group, and LSD methods are used when variance is neat；Adopted during heterogeneity of variance
With Dunnett ' s T3 methods.Completed by SPSS l7.0 softwares.
Experimental result is shown in Table 4.
The each group mouse half hemolytic value HC50 of table 4（, n=10）
（Note：Compared with blank control group, * P<0.05, * * P<0.01）
The result of table 4 shows, compared with blank control group,:The HC of high dose group in honey matrimony vine tomato50It is significantly raised, present
Positive findings.
Claims (6)
1. application of the honey matrimony vine tomato juice in strengthen immunity health food is prepared.
2. application of the honey matrimony vine tomato juice according to claim 1 in strengthen immunity health food is prepared, it is special
Levy and be, the honey matrimony vine tomato juice is consisted of the following components in percentage by weight：Concentrated tomato paste 20% ~ 30%, honey 6% ~
12%th, matrimony vine 2 ~ 8%, water 55% ~ 72%.
3. application of the honey matrimony vine tomato juice according to claim 1 in strengthen immunity health food is prepared, it is special
Levy and be, the dosage edible daily of the honey matrimony vine tomato juice is 47.7g-190.8g.
4. application of the honey matrimony vine tomato juice according to claim 1 in strengthen immunity health food is prepared, it is special
Levy and be, the usage of the honey matrimony vine tomato juice is taken directly to take or washing by water, daily edible 1-3 times.
5. application of the honey matrimony vine tomato juice according to claim 1 in strengthen immunity health food is prepared, it is special
Levy and be, the strengthen immunity is to refer to suppress delayed allergy mice ear degree, raise lymphopoiesis
Activity and NK cytoactives, raising mouse phagocytic index and carbonic clearance ability and raising half hemolytic dose.
6. application of the honey matrimony vine tomato juice according to claim 1 in strengthen immunity health food is prepared, it is special
Levy and be, the health food is plant beverage, Juice, fruit, vegetable juice or jelly.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102805284A (en) * | 2012-07-31 | 2012-12-05 | 南宁富莱欣生物科技有限公司 | Health food for strengthening immunity and production method thereof |
| CN102871120A (en) * | 2012-09-10 | 2013-01-16 | 三普药业股份有限公司 | Heath-care food for improving human immunity and preparation method thereof |
| CN103494197A (en) * | 2013-10-09 | 2014-01-08 | 吉林省现代中药工程研究中心有限公司 | Health-care food with functions of enhancing immunity and assisting to reduce blood sugar and preparation method of food |
| CN104738777A (en) * | 2015-03-06 | 2015-07-01 | 东莞市永益食品有限公司 | Honey-wolfberry-tomato juice and preparation method thereof |
-
2015
- 2015-12-15 CN CN201510928132.5A patent/CN106880045A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102805284A (en) * | 2012-07-31 | 2012-12-05 | 南宁富莱欣生物科技有限公司 | Health food for strengthening immunity and production method thereof |
| CN102871120A (en) * | 2012-09-10 | 2013-01-16 | 三普药业股份有限公司 | Heath-care food for improving human immunity and preparation method thereof |
| CN103494197A (en) * | 2013-10-09 | 2014-01-08 | 吉林省现代中药工程研究中心有限公司 | Health-care food with functions of enhancing immunity and assisting to reduce blood sugar and preparation method of food |
| CN104738777A (en) * | 2015-03-06 | 2015-07-01 | 东莞市永益食品有限公司 | Honey-wolfberry-tomato juice and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 秦竹等: "《舌尖上的中医》", 30 September 2014 * |
| 马方: "《"三高人群"怎么吃》", 31 January 2009, 中国轻工业出版社 * |
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