CN106833971A - 一种具有消肿止痛、抗菌消炎的中药手工皂及其制备方法 - Google Patents
一种具有消肿止痛、抗菌消炎的中药手工皂及其制备方法 Download PDFInfo
- Publication number
- CN106833971A CN106833971A CN201611231848.0A CN201611231848A CN106833971A CN 106833971 A CN106833971 A CN 106833971A CN 201611231848 A CN201611231848 A CN 201611231848A CN 106833971 A CN106833971 A CN 106833971A
- Authority
- CN
- China
- Prior art keywords
- extract
- inflammation
- swelling
- oil
- pain relieving
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000344 soap Substances 0.000 title claims abstract description 44
- 206010061218 Inflammation Diseases 0.000 title claims abstract description 25
- 230000008961 swelling Effects 0.000 title claims abstract description 25
- 208000002193 Pain Diseases 0.000 title claims abstract description 24
- 238000002360 preparation method Methods 0.000 title claims description 26
- 239000003814 drug Substances 0.000 title description 6
- 239000000284 extract Substances 0.000 claims abstract description 67
- 239000003921 oil Substances 0.000 claims abstract description 28
- 241000196324 Embryophyta Species 0.000 claims abstract description 21
- 240000000572 Blumea balsamifera Species 0.000 claims abstract description 20
- 235000009926 Dioscorea panthaica Nutrition 0.000 claims abstract description 17
- 241000374766 Dioscorea panthaica Species 0.000 claims abstract description 17
- 241000446281 Eschenbachia blinii Species 0.000 claims abstract description 15
- 239000000463 material Substances 0.000 claims abstract description 15
- 241001252601 Blumea Species 0.000 claims abstract description 12
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 50
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 38
- 235000019198 oils Nutrition 0.000 claims description 27
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 15
- 239000012467 final product Substances 0.000 claims description 14
- 239000007788 liquid Substances 0.000 claims description 13
- 239000000047 product Substances 0.000 claims description 12
- 235000021355 Stearic acid Nutrition 0.000 claims description 10
- 238000010438 heat treatment Methods 0.000 claims description 10
- 238000009413 insulation Methods 0.000 claims description 10
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims description 10
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims description 10
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical class CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 claims description 10
- 229910000029 sodium carbonate Inorganic materials 0.000 claims description 10
- 239000008117 stearic acid Substances 0.000 claims description 10
- 238000003756 stirring Methods 0.000 claims description 10
- 239000006228 supernatant Substances 0.000 claims description 10
- 238000001291 vacuum drying Methods 0.000 claims description 8
- 238000004821 distillation Methods 0.000 claims description 7
- 235000015112 vegetable and seed oil Nutrition 0.000 claims description 7
- 241000234273 Dioscorea Species 0.000 claims description 6
- 235000005903 Dioscorea Nutrition 0.000 claims description 6
- 235000000504 Dioscorea villosa Nutrition 0.000 claims description 6
- 244000169544 Duchesnea indica Species 0.000 claims description 6
- 235000004879 dioscorea Nutrition 0.000 claims description 6
- 238000007127 saponification reaction Methods 0.000 claims description 6
- 235000004433 Simmondsia californica Nutrition 0.000 claims description 5
- 244000044822 Simmondsia californica Species 0.000 claims description 5
- 229910052799 carbon Inorganic materials 0.000 claims description 5
- 238000004587 chromatography analysis Methods 0.000 claims description 5
- 238000000605 extraction Methods 0.000 claims description 5
- 238000004806 packaging method and process Methods 0.000 claims description 5
- 238000010992 reflux Methods 0.000 claims description 5
- 239000013049 sediment Substances 0.000 claims description 5
- 238000009423 ventilation Methods 0.000 claims description 5
- 238000005406 washing Methods 0.000 claims description 5
- 239000012153 distilled water Substances 0.000 claims description 4
- 239000004006 olive oil Substances 0.000 claims description 4
- 235000008390 olive oil Nutrition 0.000 claims description 4
- 235000019482 Palm oil Nutrition 0.000 claims description 3
- 235000018936 Vitellaria paradoxa Nutrition 0.000 claims description 3
- 241001135917 Vitellaria paradoxa Species 0.000 claims description 3
- 239000003240 coconut oil Substances 0.000 claims description 3
- 235000019864 coconut oil Nutrition 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 239000002540 palm oil Substances 0.000 claims description 3
- 229940057910 shea butter Drugs 0.000 claims description 3
- 238000001035 drying Methods 0.000 claims description 2
- 244000025254 Cannabis sativa Species 0.000 claims 1
- 239000008158 vegetable oil Substances 0.000 claims 1
- 239000002994 raw material Substances 0.000 abstract description 6
- 239000000341 volatile oil Substances 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 5
- 239000000203 mixture Substances 0.000 abstract description 5
- 239000000419 plant extract Substances 0.000 abstract description 4
- 229930003944 flavone Natural products 0.000 abstract description 3
- 235000011949 flavones Nutrition 0.000 abstract description 3
- 239000004615 ingredient Substances 0.000 abstract description 3
- 150000008442 polyphenolic compounds Chemical class 0.000 abstract description 3
- 235000013824 polyphenols Nutrition 0.000 abstract description 3
- 150000002213 flavones Chemical class 0.000 abstract description 2
- 239000002585 base Substances 0.000 description 13
- 235000019441 ethanol Nutrition 0.000 description 12
- 230000000844 anti-bacterial effect Effects 0.000 description 4
- 238000013459 approach Methods 0.000 description 4
- 238000001914 filtration Methods 0.000 description 4
- 238000005292 vacuum distillation Methods 0.000 description 4
- 206010030113 Oedema Diseases 0.000 description 3
- 241000270295 Serpentes Species 0.000 description 3
- 230000001154 acute effect Effects 0.000 description 3
- 235000021028 berry Nutrition 0.000 description 3
- 238000005119 centrifugation Methods 0.000 description 3
- 239000010931 gold Substances 0.000 description 3
- 229910052737 gold Inorganic materials 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 241000186427 Cutibacterium acnes Species 0.000 description 2
- 206010015150 Erythema Diseases 0.000 description 2
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 239000003513 alkali Substances 0.000 description 2
- 239000002260 anti-inflammatory agent Substances 0.000 description 2
- 230000001741 anti-phlogistic effect Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 210000000795 conjunctiva Anatomy 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 231100000321 erythema Toxicity 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 230000002757 inflammatory effect Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 229940055019 propionibacterium acne Drugs 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- DLYUQMMRRRQYAE-UHFFFAOYSA-N tetraphosphorus decaoxide Chemical compound O1P(O2)(=O)OP3(=O)OP1(=O)OP2(=O)O3 DLYUQMMRRRQYAE-UHFFFAOYSA-N 0.000 description 2
- 230000000451 tissue damage Effects 0.000 description 2
- 231100000827 tissue damage Toxicity 0.000 description 2
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 description 1
- DTGKSKDOIYIVQL-QXFUBDJGSA-N (-)-borneol Chemical compound C1C[C@]2(C)[C@H](O)C[C@H]1C2(C)C DTGKSKDOIYIVQL-QXFUBDJGSA-N 0.000 description 1
- 229930006703 (-)-borneol Natural products 0.000 description 1
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 description 1
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 description 1
- 208000002874 Acne Vulgaris Diseases 0.000 description 1
- 241000195622 Astasia Species 0.000 description 1
- 206010006458 Bronchitis chronic Diseases 0.000 description 1
- 241000345998 Calamus manan Species 0.000 description 1
- 241000700199 Cavia porcellus Species 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 description 1
- 244000192528 Chrysanthemum parthenium Species 0.000 description 1
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 description 1
- 241000723346 Cinnamomum camphora Species 0.000 description 1
- 244000060011 Cocos nucifera Species 0.000 description 1
- 235000013162 Cocos nucifera Nutrition 0.000 description 1
- 206010010947 Coordination abnormal Diseases 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 206010070834 Sensitisation Diseases 0.000 description 1
- 241000607768 Shigella Species 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- 208000004078 Snake Bites Diseases 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 230000003266 anti-allergic effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000008033 biological extinction Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 description 1
- 229940116229 borneol Drugs 0.000 description 1
- 206010006451 bronchitis Diseases 0.000 description 1
- 210000005252 bulbus oculi Anatomy 0.000 description 1
- 229930008380 camphor Natural products 0.000 description 1
- 229960000846 camphor Drugs 0.000 description 1
- 239000003518 caustics Substances 0.000 description 1
- 208000007451 chronic bronchitis Diseases 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 210000004087 cornea Anatomy 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 235000008384 feverfew Nutrition 0.000 description 1
- 239000012847 fine chemical Substances 0.000 description 1
- 150000002212 flavone derivatives Chemical class 0.000 description 1
- 208000003512 furunculosis Diseases 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 235000012950 rattan cane Nutrition 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 230000008313 sensitization Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 238000010181 skin prick test Methods 0.000 description 1
- 230000000192 social effect Effects 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 208000003265 stomatitis Diseases 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 206010044008 tonsillitis Diseases 0.000 description 1
- 208000004371 toothache Diseases 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 231100000611 venom Toxicity 0.000 description 1
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
- 238000004804 winding Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D9/00—Compositions of detergents based essentially on soap
- C11D9/02—Compositions of detergents based essentially on soap on alkali or ammonium soaps
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D9/00—Compositions of detergents based essentially on soap
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D9/00—Compositions of detergents based essentially on soap
- C11D9/04—Compositions of detergents based essentially on soap containing compounding ingredients other than soaps
- C11D9/06—Inorganic compounds
- C11D9/08—Water-soluble compounds
- C11D9/10—Salts
- C11D9/12—Carbonates
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D9/00—Compositions of detergents based essentially on soap
- C11D9/04—Compositions of detergents based essentially on soap containing compounding ingredients other than soaps
- C11D9/22—Organic compounds, e.g. vitamins
- C11D9/26—Organic compounds, e.g. vitamins containing oxygen
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D9/00—Compositions of detergents based essentially on soap
- C11D9/04—Compositions of detergents based essentially on soap containing compounding ingredients other than soaps
- C11D9/22—Organic compounds, e.g. vitamins
- C11D9/26—Organic compounds, e.g. vitamins containing oxygen
- C11D9/267—Organic compounds, e.g. vitamins containing oxygen containing free fatty acids
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D9/00—Compositions of detergents based essentially on soap
- C11D9/04—Compositions of detergents based essentially on soap containing compounding ingredients other than soaps
- C11D9/22—Organic compounds, e.g. vitamins
- C11D9/38—Products in which the composition is not well defined
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
本发明涉及一种消肿止痛、抗菌消炎的艾纳香手工皂，具体包括艾纳香油、蛇莓提取物、金龙胆草提取物、黄山药提取物、基础植物精油等原料制成，本发明手工皂中添加了中药提取物成分，通过组方配比及相关辅料的合理配比，确保了在添加植物提取物后，保证添加的植物精油、黄酮或者多酚等有益成分不被强碱破坏，从而达到消肿止痛、抗菌消炎的功效。
Description
技术领域
本发明涉及日用品的加工领域，尤其涉及一种具有消肿止痛、抗菌消炎的中药手工皂及其制备方法。
背景技术
随着人们生活水平的提高，人们对洁肤类产品提出了更高的的安全性和健康保健要求，同时保护生态环境，倡导低碳生活的天然环保理念深入人心。目前市场上广泛使用的各类洗面奶、沐浴露产品，使用的大量精细化工产品，并且生产过程产生三废，对人体产生一定的未知不良作用，尤其是婴幼儿和孕妇。艾纳香油为我国贵州少数民族用药，属菊科植物艾纳香的叶的升华物经压榨分离而得的油；是提取天然冰片产品的附属产品，其中含有左旋龙脑、樟脑、挥发油、油脂及其他有用成份，具有很好的杀菌消炎作用；黄山药为缠绕藤本，现代药理研究表明，其具有解毒消肿，止痛的功效；金龙胆草，为菊科植物，具有清热消炎，泻火解毒的功效；其提取物临床上常用于急性黄疸型肝炎，牙痛，慢性气管炎，口腔炎，咽喉炎，扁桃体炎，肾炎等辅助治疗；蛇莓作为常用中药，在中国具有悠久的药用历史，历代本草皆有收载，具有有清热解毒、活血散瘀、收敛止血作用，又能治毒蛇咬伤，敷治疔疮等，对金黄色葡萄球菌、志贺痢疾杆菌、绿脓杆菌有抑制作用。
现代药理学研究表明，植物黄酮、多酚和精油类成分具有抗菌、美白抗过敏、抗炎等多种生理活性，为此，研制出含有天然植物护肤成分的手工皂，可以替代大量使用的化学合成的各类洗浴产品，并具备很好的护肤效果和环保社会意义。
发明内容
本发明的目的在于，为了满足市场的需求，本发明原料及辅料通过合理配方，获得了一种具有消肿止痛、抗菌消炎的效果的手工皂；同时，为了克服现有技术中存在的目前手工皂强碱皂化工艺对植物精油及植物提取物的破坏作用，本发明各组原料及辅料的合理配比使用，最大限度地保持手工皂中添加的植物提取物的有效性，满足市场的需求。
为了解决上述技术问题，本发明所采用的技术方案为：
一种消肿止痛、抗菌消炎的艾纳香手工皂，由以下原料制备而成：艾纳香油10-15％、金龙胆草提取物1-3％、蛇莓提取物1-3％、黄山药提取物1-3％及辅料76-87％。
上述的一种消肿止痛、抗菌消炎的艾纳香手工皂，所述的辅料包括：氢氧化钠3-6％、丙二醇4-7％、山梨醇4-7％、硬脂酸5-10％、碳酸钠8-12％、基础植物油32-65％、蒸馏水15-20％。
上述的一种消肿止痛、抗菌消炎的艾纳香手工皂，所述的基础植物油为橄榄油、椰子油、荷荷巴油、棕榈油、乳木果油中的一种或多种混合。
上述的一种消肿止痛、抗菌消炎的艾纳香手工皂，所述金龙胆草提取物的制备方法为：将金龙胆草按料液比1∶8-10加入到65％乙醇中，于70-80℃加热回流提取2-3h，在2000-3500rpm条件下离心15-30min，反复提取三次，合并上清液，减压蒸馏，干燥粉碎，即得。
上述的一种消肿止痛、抗菌消炎的艾纳香手工皂，所述蛇莓提取物的制备方法为：按料液1∶8-10将蛇莓药材用70％乙醇于65℃恒温浸提24h，过滤，减压浓缩至膏状，于真空干燥箱中烘干，粉碎，即得。
上述的一种消肿止痛、抗菌消炎的艾纳香手工皂，所述黄山药提取物物的制备方法为：将黄山药置于80-95℃水中浸提2-3h，于3500rpm条件下离心20-30min，收集上清液，浓缩，用2倍量的95％乙醇醇析，收集沉淀物，用无水乙醇洗涤后干燥，粉碎即得。
上述的一种消肿止痛、抗菌消炎的艾纳香手工皂的制备方法，包括以下步骤：(1)、按照选定的重量百分比的基础植物油加热50-60℃搅拌，混合均匀；再加入选定重量比例的丙二醇、山梨醇、硬脂酸、碳酸钠混合均匀，然后降温至45℃，得A组分备用；(2)、将选定的重量百分比的氢氧化钠用蒸馏水溶解，搅拌保温2小时，控制温度至40-45℃，得B组分备用；(3)、将步骤B组分缓慢加入到A组分中，搅拌皂化，至皂液pH无限接近10；得到C组分备用；(4)、将C组分45℃保温条件下，加入选定重量比例的艾纳香油、龙胆草提取物、蛇莓提取物、黄山药提取物，充分混合均匀，将得到的皂液倒入模具中，封盖，40-45℃保温48h，脱模，阴凉通风处晾干1-2个月，包装制成成品。
具体实施方式
实施例1
一种消肿止痛、抗菌消炎的艾纳香手工皂，以重量计算包括如下制备原料组分：金龙胆草提取物1％、蛇莓提取物3％、黄山药提取物1％，艾纳香油15％、氢氧化钠3％、丙二醇7％、山梨醇4％、硬脂酸10％、碳酸钠8％、基础植物油37％、蒸馏水15％；其中基础植物油为橄榄油、椰子油、荷荷巴油其质量比为1∶2∶1的混合物；
上述手工皂的制备方法，包括如下步骤：
(1)、提取物的制备：
A：金龙胆草提取物的制备：将金龙胆草按料液比1∶8-10加入到65％乙醇中，于70-80℃加热回流提取2-3h，在2000-3500rpm条件下离心15-30min，反复提取三次，合并上清液，减压蒸馏，干燥粉碎，即得。
B：蛇莓提取物的制备：按料液1∶8-10将蛇莓药材用70％乙醇于65℃恒温浸提24h，过滤，减压浓缩至膏状，于真空干燥箱中烘干，粉碎，即得。
C：黄山药提取物物的制备：将黄山药置于80-95℃水中浸提2-3h，于3500rpm条件下离心20-30min，收集上清液，浓缩，用2倍量的95％乙醇醇析，收集沉淀物，用无水乙醇洗涤后干燥，粉碎即得。
(2)、按照选定的重量百分比的基础植物油加热50-60℃搅拌，混合均匀；再加入选定重量比例的丙二醇、山梨醇、硬脂酸、碳酸钠混合均匀，然后降温至45℃，得A组分备用；
(3)、将选定的重量百分比的氢氧化钠用蒸馏水溶解，搅拌保温2小时，控制温度至40-45℃，得B组分备用；
(4)、将步骤B组分缓慢加入到A组分中，搅拌皂化，至皂液pH无限接近10；得到C组分备用；
(5)、将C组分45℃保温条件下，加入选定重量比例的艾纳香油、龙胆草提取物、蛇莓提取物、黄山药提取物，充分混合均匀，将得到的皂液倒入模具中，封盖，40-45℃保温48h，脱模，阴凉通风处晾干1-2个月，包装制成成品。
实施例2
一种消肿止痛、抗菌消炎的艾纳香手工皂，以重量计算包括如下制备原料组分：金龙胆草提取物3％、蛇莓提取物1％、黄山药提取物3％，艾纳香油10％、氢氧化钠6％、丙二醇4％、山梨醇7％、硬脂酸5％、碳酸钠12％、基础植物油39％、蒸馏水20％；其中基础植物油为椰子油、荷荷巴油、乳木果油其质量比为2∶2∶1的混合物；
上述手工皂的制备方法，包括如下步骤：
(1)、提取物的制备：
A：金龙胆草提取物的制备：将金龙胆草按料液比1∶8-10加入到65％乙醇中，于70-80℃加热回流提取2-3h，在2000-3500rpm条件下离心15-30min，反复提取三次，合并上清液，减压蒸馏，干燥粉碎，即得。
B：蛇莓提取物的制备：按料液1∶8-10将蛇莓药材用70％乙醇于65℃恒温浸提24h，过滤，减压浓缩至膏状，于真空干燥箱中烘干，粉碎，即得。
C：黄山药提取物物的制备：将黄山药置于80-95℃水中浸提2-3h，于3500rpm条件下离心20-30min，收集上清液，浓缩，用2倍量的95％乙醇醇析，收集沉淀物，用无水乙醇洗涤后干燥，粉碎即得。
(2)、按照选定的重量百分比的基础植物油加热50-60℃搅拌，混合均匀；再加入选定重量比例的丙二醇、山梨醇、硬脂酸、碳酸钠混合均匀，然后降温至45℃，得A组分备用；
(3)、将选定的重量百分比的氢氧化钠用蒸馏水溶解，搅拌保温2小时，控制温度至40-45℃，得B组分备用；
(4)、将步骤B组分缓慢加入到A组分中，搅拌皂化，至皂液pH无限接近10；得到C组分备用；
(5)、将C组分45℃保温条件下，加入选定重量比例的艾纳香油、龙胆草提取物、蛇莓提取物、黄山药提取物，充分混合均匀，将得到的皂液倒入模具中，封盖，40-45℃保温48h，脱模，阴凉通风处晾干1-2个月，包装制成成品。
实施例3
一种消肿止痛、抗菌消炎的艾纳香手工皂，以重量计算包括如下制备原料组分：金龙胆草提取物2％、蛇莓提取物2％、黄山药提取物2％，艾纳香油12％、氢氧化钠5％、丙二醇5％、山梨醇5％、硬脂酸8％、碳酸钠10％、基础植物油31％、蒸馏水18％；其中基础植物油为橄榄油、荷荷巴油、棕榈油其质量比为1∶2∶2的混合物；
上述手工皂的制备方法，包括如下步骤：
(1)、提取物的制备：
A：金龙胆草提取物的制备：将金龙胆草按料液比1∶8-10加入到65％乙醇中，于70-80℃加热回流提取2-3h，在2000-3500rpm条件下离心15-30min，反复提取三次，合并上清液，减压蒸馏，干燥粉碎，即得。
B：蛇莓提取物的制备：按料液1∶8-10将蛇莓药材用70％乙醇于65℃恒温浸提24h，过滤，减压浓缩至膏状，于真空干燥箱中烘干，粉碎，即得。
C：黄山药提取物物的制备：将黄山药置于80-95℃水中浸提2-3h，于3500rpm条件下离心20-30min，收集上清液，浓缩，用2倍量的95％乙醇醇析，收集沉淀物，用无水乙醇洗涤后干燥，粉碎即得。
(2)、按照选定的重量百分比的基础植物油加热50-60℃搅拌，混合均匀；再加入选定重量比例的丙二醇、山梨醇、硬脂酸、碳酸钠混合均匀，然后降温至45℃，得A组分备用；
(3)、将选定的重量百分比的氢氧化钠用蒸馏水溶解，搅拌保温2小时，控制温度至40-45℃，得B组分备用；
(4)、将步骤B组分缓慢加入到A组分中，搅拌皂化，至皂液pH无限接近10；得到C组分备用；
(5)、将C组分45℃保温条件下，加入选定重量比例的艾纳香油、龙胆草提取物、蛇莓提取物、黄山药提取物，充分混合均匀，将得到的皂液倒入模具中，封盖，40-45℃保温48h，脱模，阴凉通风处晾干1-2个月，包装制成成品。
上述实施例1-3的样品依据标准QB/T2485-2008随机进行了抽样检测，结果本发明手工皂中总有效物含量、水分和挥发物、总游离碱、游离苛性碱、氯化物、总五氧化二磷等项目均符合标准要求；
本发明相对于现有技术的优势为通过中药提取物合理配方，以及相关辅料的合理配合，确保在添加植物提取物后，保证添加的植物精油、黄酮或者多酚等有益成分不被强碱破坏，同时，本发明手工皂中原料药艾纳香油、金龙胆草提取物、蛇莓提取物、黄山药提取物的合理配比添加与基础植物油进行配比，达到了具有消肿止痛、抗菌消炎的功效。
本实施例1-3方式实施的手工皂，兼具杀菌消炎等功能；痤疮丙酸杆菌抑制试验发现，本实施1-3方式实施的手工皂对引起痤疮的痤疮丙酸杆菌的抑菌和杀菌能力较强，与市面上同等价位同类产品相比，杀菌比率提高12.3％；皮损严重程度评价发现，皮肤表层有红斑的实验动物，皮损消退率为24.5％；急性皮肤刺激性试验发现，家兔皮肤涂敷后局部产生的无炎性变化和组织损伤，无红斑，水肿；急性眼刺激性试验发现，家兔眼球表面接触面后无炎性变化和组织损伤，角膜无溃疡形成或混浊、虹膜正常、指睑结膜和球结膜部位血管正常、无水肿；皮肤变态反应试验发现，试豚鼠皮肤无红斑和水肿，致敏率0.003％在可接受范围内，无哮喘、站立不稳或休克等严重过敏现象。同时依照本实施例1-3方式实施的手工皂，对于长期用于手部劳作或创伤造成手部的肿痛，具有明显的改善作用。
综上所述，以上具体实施方式仅用于说明本发明而不用于限制本发明的范围，本领域技术人员对本发明的各种等价形式的修改均落于本申请所附权利要求所限定的范围。
Claims (7)
1.一种消肿止痛、抗菌消炎的艾纳香手工皂，其特征在于由以下原料制备而成：艾纳香油10-15％、蛇莓提取物1-3％、金龙胆草提取物1-3％、黄山药提取物1-3％及辅料76-87％。
2.根据权利要求1所述的一种消肿止痛、抗菌消炎的艾纳香手工皂，其特征在于：所述的辅料包括：氢氧化钠3-6％、丙二醇4-7％、山梨醇4-7％、硬脂酸5-10％、碳酸钠8-12％、基础植物油32-65％、蒸馏水15-20％。
3.根据权利要求2所述的一种消肿止痛、抗菌消炎的艾纳香手工皂，其特征在于：所述的基础植物油为橄榄油、椰子油、荷荷巴油、棕榈油、乳木果油中的一种或多种混合。
4.根据权利要求1所述的一种消肿止痛、抗菌消炎的艾纳香手工皂，其特征在于，所述金龙胆草提取物的制备方法为：将金龙胆草按料液比1∶8-10加入到65％乙醇中，于70-80℃加热回流提取2-3h，在2000-3500rpm条件下离心15-30min，反复提取三次，合并上清液，减压蒸馏，干燥粉碎，即得。
5.根据权利要求1所述的一种消肿止痛、抗菌消炎的艾纳香手工皂，其特征在于，所述蛇莓提取物的制备方法为：按料液1∶8-10将蛇莓药材用70％乙醇于65℃恒温浸提24h，过滤，减压浓缩至膏状，于真空干燥箱中烘干，粉碎，即得。
6.根据权利要求1所述的一种消肿止痛、抗菌消炎的艾纳香手工皂，其特征在于，所述黄山药提取物物的制备方法为：将黄山药置于80-95℃水中浸提2-3h，于3500rpm条件下离心20-30min，收集上清液，浓缩，用2倍量的95％乙醇醇析，收集沉淀物，用无水乙醇洗涤后干燥，粉碎即得。
7.根据权利要求1所述的一种消肿止痛、抗菌消炎的艾纳香手工皂的制备方法，其特征在于包括以下步骤：(1)、按照选定的重量百分比的基础植物油加热50-60℃搅拌，混合均匀；再加入选定重量比例的丙二醇、山梨醇、硬脂酸、碳酸钠混合均匀，然后降温至45℃，得A组分备用；(2)、将选定的重量百分比的氢氧化钠用蒸馏水溶解，搅拌保温2小时，控制温度至40-45℃，得B组分备用；(3)、将步骤B组分缓慢加入到A组分中，搅拌皂化，至皂液pH无限接近10；得到C组分备用；(4)、将C组分45℃保温条件下，加入选定重量比例的艾纳香油、龙胆草提取物、蛇莓提取物、黄山药提取物，充分混合均匀，将得到的皂液倒入模具中，封盖，40-45℃保温48h，脱模，阴凉通风处晾干1-2个月，包装制成成品。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611231848.0A CN106833971A (zh) | 2016-12-28 | 2016-12-28 | 一种具有消肿止痛、抗菌消炎的中药手工皂及其制备方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611231848.0A CN106833971A (zh) | 2016-12-28 | 2016-12-28 | 一种具有消肿止痛、抗菌消炎的中药手工皂及其制备方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106833971A true CN106833971A (zh) | 2017-06-13 |
Family
ID=59113980
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611231848.0A Pending CN106833971A (zh) | 2016-12-28 | 2016-12-28 | 一种具有消肿止痛、抗菌消炎的中药手工皂及其制备方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106833971A (zh) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108310475A (zh) * | 2018-01-08 | 2018-07-24 | 广州润虹医药科技股份有限公司 | 一种防堵塞吸盘式负压引流装置 |
| CN113956929A (zh) * | 2021-11-12 | 2022-01-21 | 中国热带农业科学院热带作物品种资源研究所 | 一种含左旋龙脑的复方冷制皂及其制备方法 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103301051A (zh) * | 2012-03-07 | 2013-09-18 | 南京华狮化工有限公司 | 一种透明美容皂组合物 |
| CN104403843A (zh) * | 2014-11-24 | 2015-03-11 | 张彬 | 一种手工皂及制备方法 |
| CN104593178A (zh) * | 2014-11-19 | 2015-05-06 | 吉林农业大学 | 一种含有人参稀有皂苷的多功能手工皂 |
| CN106010831A (zh) * | 2016-05-24 | 2016-10-12 | 江苏耐雀生物工程技术有限公司 | 一种手工皂及其制备方法 |
-
2016
- 2016-12-28 CN CN201611231848.0A patent/CN106833971A/zh active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103301051A (zh) * | 2012-03-07 | 2013-09-18 | 南京华狮化工有限公司 | 一种透明美容皂组合物 |
| CN104593178A (zh) * | 2014-11-19 | 2015-05-06 | 吉林农业大学 | 一种含有人参稀有皂苷的多功能手工皂 |
| CN104403843A (zh) * | 2014-11-24 | 2015-03-11 | 张彬 | 一种手工皂及制备方法 |
| CN106010831A (zh) * | 2016-05-24 | 2016-10-12 | 江苏耐雀生物工程技术有限公司 | 一种手工皂及其制备方法 |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108310475A (zh) * | 2018-01-08 | 2018-07-24 | 广州润虹医药科技股份有限公司 | 一种防堵塞吸盘式负压引流装置 |
| CN113956929A (zh) * | 2021-11-12 | 2022-01-21 | 中国热带农业科学院热带作物品种资源研究所 | 一种含左旋龙脑的复方冷制皂及其制备方法 |
| WO2023082422A1 (zh) * | 2021-11-12 | 2023-05-19 | 中国热带农业科学院热带作物品种资源研究所 | 一种含左旋龙脑的复方冷制皂及其制备方法 |
| CN113956929B (zh) * | 2021-11-12 | 2023-06-09 | 中国热带农业科学院热带作物品种资源研究所 | 一种含左旋龙脑的复方冷制皂及其制备方法 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Alamgir | Herbal drugs: their collection, preservation, and preparation; evaluation, quality control, and standardization of herbal drugs | |
| CN101185621A (zh) | 一种中草药抗菌洗手液及其制备方法 | |
| KR101565778B1 (ko) | 나노 산화아연이 함유된 항균 비누의 제조방법 및 이에 의해 제조된 항균비누 | |
| CN105062722A (zh) | 一种含桑椹及衍生品的手工皂及其制备方法 | |
| CN106619380A (zh) | 一种祛痘精华液 | |
| Wijayawardhana et al. | Antimicrobial activity of a combination of three natural plant extracts and development of a herbal soap. | |
| CN100404054C (zh) | 一种煮散型中药抗菌消炎剂及其制备方法和应用 | |
| KR100847478B1 (ko) | 금 또는 은 나노입자 및 까마중 추출물의 중합체를유효성분으로 함유한 기능성 비누 조성물 및 이의 제조방법 | |
| KR100973248B1 (ko) | 계피 비누 및 이를 제조하는 방법 | |
| CN106833971A (zh) | 一种具有消肿止痛、抗菌消炎的中药手工皂及其制备方法 | |
| CN109010178B (zh) | 一种沐浴露及其生产工艺 | |
| CN106038378A (zh) | 一种母婴用压缩干巾及其制备方法 | |
| CN100547063C (zh) | 荔枝核提取物在制备杀灭螨虫的肥皂中的应用 | |
| CN106421511A (zh) | 一种芦荟抑菌组合物及其制备方法 | |
| US5980903A (en) | Composition for the treatment of viral infections including HIV | |
| CN103284162A (zh) | 一种库拉索芦荟凝胶功能性食品 | |
| CN103710177B (zh) | 一种去粉刺、去痘广藿香精油手工皂及其制作方法 | |
| KR20250054648A (ko) | 두피 케어 및 모발 상태 개선용 샴푸 조성물 | |
| KR101883720B1 (ko) | 천연자원을 이용한 항균 비누 조성물 | |
| CN110870885B (zh) | 一种具有清洁、杀菌、保湿作用的药液及其应用 | |
| CN108553543A (zh) | 一种紫草膏及其制备方法 | |
| CN107468590A (zh) | 一种消炎祛痘膏及其制备方法 | |
| CN113388460A (zh) | 一种含牡丹花的清香型香皂及其制备方法 | |
| CN104739952A (zh) | 具有促进伤口愈合作用的复方茶树精油 | |
| CN105311328A (zh) | 一种治疗妇科炎症的中药组合物及其应用 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170613 |