CN106822676A - 一种治疗痰瘀互结型胸膜炎的汤剂药物及其制备方法 - Google Patents

一种治疗痰瘀互结型胸膜炎的汤剂药物及其制备方法 Download PDF

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CN106822676A
CN106822676A CN201710092744.4A CN201710092744A CN106822676A CN 106822676 A CN106822676 A CN 106822676A CN 201710092744 A CN201710092744 A CN 201710092744A CN 106822676 A CN106822676 A CN 106822676A
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孙素蓉
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Chengdu Fengmi Biotechnology Co Ltd
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Abstract

本发明属于中药制剂领域，目的是根据中医对痰瘀互结型胸膜炎的认识机理而提供的一种治疗痰瘀互结型胸膜炎的汤剂药物，所述药物的各个组分及其质量份比如下：蛇麻草6g、麻黄8g、铁杆蒿14g、桂枝8g、知母12g、穿心草12g、鱼腥草20g、水蕨26g、竹叶榕70g、柴胡10g、黄芩12g、斑叶兰12g、银线草4g、薏苡仁35g、香橼5g、扁豆28g、紫参170g、杏仁8g、草香附7g、生石膏35g、白郎苔28g；本发明提供的药物是一个标本兼治的中药组方。

Description

一种治疗痰瘀互结型胸膜炎的汤剂药物及其制备方法
技术领域
本发明属于中药制剂领域，具体涉及一种治疗痰瘀互结型胸膜炎的汤剂药物，特别是供痰瘀互结型胸膜炎患者使用的汤剂药物及其制备方法的领域。
背景技术
据文献资料显示：胸膜炎最常见的症状为胸痛。胸痛常突然出现，程度差异较大，可为不明确的不适或严重的刺痛，可仅在患者深呼吸或咳嗽时出现，亦可持续存在并因深呼吸或咳嗽而加剧。胸痛为壁层胸膜的炎症所致，通常出现于正对炎症部位的胸壁。亦可表现为腹部、颈部或肩部的牵涉痛 。胸膜炎由于深呼吸可致疼痛，故常引起呼吸浅快，患侧肌肉运动较对侧为弱。现有的治疗多为西药治疗，副作用大。
那么，就如何找到一种可有效治疗上述痰瘀互结型胸膜炎的药物，是本领域技术人员亟待要解决的课题。
发明内容
随着我国中医中药学的不断发展，在治疗痰瘀互结型胸膜炎上，人们逐渐意识到了中医治疗痰瘀互结型胸膜炎的优点，且在治疗过程中疗效好、见效快、毒副作用小等优势，针对现有西医治疗痰瘀互结型胸膜炎的现状，本发明的目的是在于提供一种治疗痰瘀互结型胸膜炎的汤剂药物，以解决痰瘀互结型胸膜炎患者早日恢复健康的问题。该药物是以常见的中药为原料，通过选择合理的药物及质量份比，可有效治疗上述痰瘀互结型胸膜炎。
为达到上述发明的目的，本发明所采用的技术方案为：提供一种治疗痰瘀互结型胸膜炎的汤剂药物及其制备方法，其特征在于，所述药物的各个组分及其质量份比如下所示：
蛇麻草3～8g、麻黄3～10g、铁杆蒿8～18g、桂枝3～10g、知母6～15g、穿心草9～16g、鱼腥草15～25g、水蕨15～35g、竹叶榕50～85g、柴胡3～12g、黄芩5～16g、斑叶兰5～16g、银线草2.5～5g、薏苡仁15～50g、香橼3～6g、扁豆15～35g、紫参50～220g、杏仁3～10g、草香附3～9g、生石膏15～45g、白郎苔25～45g。
一种治疗痰瘀互结型胸膜炎的汤剂药物及其制备方法，其特征在于，所述药物的各个组分及其质量份比如下所示：
蛇麻草5～7g、麻黄5～9g、铁杆蒿10～16g、桂枝5～9g、知母8～13g、穿心草10～14g、鱼腥草17～22g、水蕨17～31g、竹叶榕60～75g、柴胡5～11g、黄芩8～14g、斑叶兰6～14g、银线草3～4.5g、薏苡仁17～40g、香橼4～5.5g、扁豆18～31g、紫参60～200g、杏仁5～9g、草香附5～8g、生石膏17～40g、白郎苔28～41g。
一种治疗痰瘀互结型胸膜炎的汤剂药物及其制备方法，其特征在于，所述“最佳方案”的药物的各个组分及其质量份比如下所示：
蛇麻草6g、麻黄8g、铁杆蒿14g、桂枝8g、知母12g、穿心草12g、鱼腥草20g、水蕨26g、竹叶榕70g、柴胡10g、黄芩12g、斑叶兰12g、银线草4g、薏苡仁35g、香橼5g、扁豆28g、紫参170g、杏仁8g、草香附7g、生石膏35g、白郎苔28g。
一种治疗痰瘀互结型胸膜炎的汤剂药物及其制备方法，其特征在于，所述方法包括如下步骤制备而成：
A、将上述原料中药拣去杂质和粉尘后，按照质量份比分别粉碎成粗粒状包煎；
B、将包好的原料中药放入冷开水中浸泡半个小时，然后再将浸泡好的药物和浸泡药物的澄清液一并放入砂锅内，注入过药52mm的冷开水进行第一次煎煮50分钟，滤取药液后，再次注入过药50mm的微温开水进行第二次煎煮35分钟，二次混合浓缩成50%的中药液400毫升备用。
一种治疗痰瘀互结型胸膜炎的汤剂药物及其制备方法，其特征在于，所述服用方法为：将制备好的中药液以一天服用，每日一剂，早晚各服一次，给药量200毫升/次，饭前服。服药15～38天，症状消失，病获痊愈。
本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料，充分发挥各组分的药理功效：
蛇麻草，性味：性平、味苦，具有健胃消食、化痰止咳、抗痨、安神利尿之功效，用于治疗食欲不振、腹胀、肺结核、胸膜炎、失眠、癔病、浮肿、膀胱炎；
麻黄，性味：辛苦、温，具有发汗、平喘、利水之功效，用于治疗伤寒表实、发热恶寒无汗、头痛鼻塞、骨节疼痛、咳嗽气喘、风水浮肿、小便不利、风邪顽痹、皮肤不仁、风疹瘙痒；
铁杆蒿，性味：苦、温，具有散寒润肺、降气化痰、止咳、利尿之功效，用于治疗治阴虚咳血、慢性支气管炎；
桂枝，性味：辛、甘、温，具有发汗解肌、温通经脉、助阳化气、平冲降气之功效，用于治疗风寒感冒、脘腹冷痛、血寒经闭、关节痹痛、痰饮、水肿、心悸、奔豚；
知母，性味：味苦、性寒，具有清热泻火、滋阴润燥、止渴除烦之功效，用于治疗温热病、高热烦渴、咳嗽气喘、燥咳、便秘、骨蒸潮热、虚烦不眠、消渴淋浊；
穿心草，性味：微甘、微苦、性凉，具有清热解毒、理气活血之功效，用于治疗肺热咳嗽、肝炎、钩端螺旋体病、胸痛、胃痛、跌打损伤、毒蛇咬伤；
鱼腥草，性味：辛、寒，具有清热解毒，利尿消肿之功效，用于治疗肺炎、肺脓疡、热痢、疟疾、水肿、淋病、白带、痈肿、痔疮、脱肛、湿疹、秃疮、疥癣；
水蕨，性味：甘、苦、寒，无毒，具有消积、散瘀、解毒、止血之功效，用于治疗腹中痞块、痢疾、小儿胎毒、疮疖、跌失损伤、外伤出血；
竹叶榕，性味：甘、苦、温，具有祛痰止咳、行气活血、祛风除湿之功效，用于治疗咳嗽、胸痛、跌打肿痛、肾炎、风湿骨痛、乳少等症；
柴胡，性味：味苦、辛、性微寒，具有解表退热、疏肝解郁、升举阳气之功效，用于治疗外感发热、寒热往来、疟疾、肝郁胁痛乳胀、头痛头眩、月经不调、气虚下陷之脱肛、子宫脱垂、胃下垂等症；
黄芩，性味：味苦、性寒，具有清热泻火、燥湿解毒、止血、安胎之功效，用于治疗肺热咳嗽、热病高热神昏、肝火头痛、目赤肿痛、湿热黄疸、泻痢、热淋、吐衄血、崩漏、胎热不安、痈肿疔疮；
斑叶兰，性味：淡、寒，具有清肺止咳、解毒消肿、止痛之功效，用于治疗肺结核咳嗽、支气管炎，外用治毒蛇咬伤、痈疖疮疡等症；
银线草，性味：辛苦、温，有毒，具有散寒、祛风、行瘀、解毒之功效，用于治疗风寒咳嗽、妇女经闭、风痒、跌打、痈肿疮疖等症；
薏苡仁，性味：甘、淡、微寒，具有利湿健脾、舒筋除痹、清热排脓之功效，用于治疗水肿、脚气、小便淋沥、湿温病、泄泻带下、风湿痹痛、筋脉拘挛、肺痈、肠痈、扁平疣；
香橼，性味：辛、苦、酸、温，具有理气降逆、宽胸化痰之功效，用于治疗胸腹满闷、胁肋胀痛、咳嗽痰多；
扁豆，性味：甘、平，具有健脾和中、消暑化湿之功效，用于治疗暑湿吐泻、脾虚呕逆、食少久泄、水停消渴、赤白带下、小儿疳积等症；
紫参，性味：性平、味苦、辛，具有清热解毒、活血理气止痛之功效，用于治疗急慢性肝炎、脘胁胀痛、湿热带下、乳腺炎、疔肿等症；
杏仁，性味：苦、温，有毒，具有祛痰止咳、平喘、润肠、下气开痹之功效，用于治疗外感咳嗽、喘满、伤燥咳嗽、寒气奔豚、惊痫、胸痹、食滞脘痛、血崩、耳聋、疳肿胀、湿热淋证、疥疮、喉痹、肠燥便秘；
草香附，性味：平、辛、微苦，具有理气止疼、活血调经之功效，用于治疗肝郁气滞、胸胁疼痛、月经不调、崩中带下；
生石膏，性味：辛甘、寒，具有解肌清熱、除煩止渴之功效，用于治疗熱病壯熱不退、心煩神昏、譫語發狂、口渴咽干、肺熱喘急、中暑自汗、胃火頭痛、牙痛、熱毒壅盛、發斑發疹、口舌生瘡，鍛敷生肌斂瘡，外治癰疽瘡瘍、潰不收口、湯火燙傷；
白郎苔，性味：甘、苦、平，具有理气止痛、驱风除湿之功效，用于治疗小儿夜哭、风湿骨痛。
本发明药物是基于中医治疗痰瘀互结型胸膜炎的原则，从依据痰瘀互结型胸膜炎的病理机制及药理作用认为：就痰瘀互结型胸膜炎，本发明所提供的药物中的各原料中药药效共奏，对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述痰瘀互结型胸膜炎的治疗而提出的一种中药配方，采用该配方制备的药物药效好，见效快，是一个标本兼治的中药组方，特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述：
实施例1：
一种治疗痰瘀互结型胸膜炎的汤剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
蛇麻草6g、麻黄8g、铁杆蒿14g、桂枝8g、知母12g、穿心草12g、鱼腥草20g、水蕨26g、竹叶榕70g、柴胡10g、黄芩12g、斑叶兰12g、银线草4g、薏苡仁35g、香橼5g、扁豆28g、紫参170g、杏仁8g、草香附7g、生石膏35g、白郎苔28g。
实施例2：
一种治疗痰瘀互结型胸膜炎的汤剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
蛇麻草7g、麻黄9g、铁杆蒿16g、桂枝9g、知母13g、穿心草14g、鱼腥草22g、水蕨31g、竹叶榕75g、柴胡11g、黄芩14g、斑叶兰14g、银线草4.5g、薏苡仁40g、香橼5.5g、扁豆31g、紫参200g、杏仁9g、草香附8g、生石膏40g、白郎苔41g。
实施例3：
一种治疗痰瘀互结型胸膜炎的汤剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
蛇麻草8g、麻黄10g、铁杆蒿18g、桂枝10g、知母15g、穿心草16g、鱼腥草25g、水蕨35g、竹叶榕85g、柴胡12g、黄芩16g、斑叶兰16g、银线草5g、薏苡仁50g、香橼6g、扁豆35g、紫参220g、杏仁10g、草香附9g、生石膏45g、白郎苔45g。
典型病例
经临床诊断治疗痰瘀互结型胸膜炎患者共430例，年龄为46岁以上的280例，只有150例为46岁以下。430例患者中痊愈的395例，有效的35例，总有效率达100%。

Claims (3)

1.一种治疗痰瘀互结型胸膜炎的汤剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
蛇麻草3～8g、麻黄3～10g、铁杆蒿8～18g、桂枝3～10g、知母6～15g、穿心草9～16g、鱼腥草15～25g、水蕨15～35g、竹叶榕50～85g、柴胡3～12g、黄芩5～16g、斑叶兰5～16g、银线草2.5～5g、薏苡仁15～50g、香橼3～6g、扁豆15～35g、紫参50～220g、杏仁3～10g、草香附3～9g、生石膏15～45g、白郎苔25～45g。
2.根据权利要求1所述的治疗痰瘀互结型胸膜炎的汤剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
蛇麻草5～7g、麻黄5～9g、铁杆蒿10～16g、桂枝5～9g、知母8～13g、穿心草10～14g、鱼腥草17～22g、水蕨17～31g、竹叶榕60～75g、柴胡5～11g、黄芩8～14g、斑叶兰6～14g、银线草3～4.5g、薏苡仁17～40g、香橼4～5.5g、扁豆18～31g、紫参60～200g、杏仁5～9g、草香附5～8g、生石膏17～40g、白郎苔28～41g。
3.根据权利要求1至2所述的治疗痰瘀互结型胸膜炎的汤剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
蛇麻草6g、麻黄8g、铁杆蒿14g、桂枝8g、知母12g、穿心草12g、鱼腥草20g、水蕨26g、竹叶榕70g、柴胡10g、黄芩12g、斑叶兰12g、银线草4g、薏苡仁35g、香橼5g、扁豆28g、紫参170g、杏仁8g、草香附7g、生石膏35g、白郎苔28g。
CN201710092744.4A 2017-02-21 2017-02-21 一种治疗痰瘀互结型胸膜炎的汤剂药物及其制备方法 Pending CN106822676A (zh)

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