CN106822617A - 一种橡实收敛固脱口服液及其制备方法 - Google Patents

一种橡实收敛固脱口服液及其制备方法 Download PDF

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CN106822617A
CN106822617A CN201510860971.8A CN201510860971A CN106822617A CN 106822617 A CN106822617 A CN 106822617A CN 201510860971 A CN201510860971 A CN 201510860971A CN 106822617 A CN106822617 A CN 106822617A
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张昕
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Heilongjiang Zhicheng Medicine Technology Co Ltd
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Abstract

一种橡实收敛固脱口服液及其制备方法,由原料按以下重量份数制备而成,橡实35-45份、女儿红根10-15份、竹沥10-15份、没食子6-8份、枸骨叶6-8份、蘡薁根6-8份、油柑根3-5份、柚皮3-5份、榆白皮3-5份、榆叶3-5份、蜂蜜4-6份、蔗糖2-4份、白砂糖2-4份、木糖醇2-4份、柠檬酸1-3份、纯净水500份;其制备方法的主要步骤为:a、原料预处理;b、粉碎;c、提取;d、离心分离;e、超滤;f、浓缩;g、混合。本发明的一种橡实收敛固脱口服液,长期服用具有收敛固脱、止血、解毒的功效。

Description

一种橡实收敛固脱口服液及其制备方法
技术领域
本发明涉及一种保健品,特别是一种橡实收敛固脱口服液及其制备方法。
背景技术
痢疾则腹泻。腹泻是临床上常见的症状,可因多种疾病而引起。正常人每天排便1次,排出粪便的量约200~400g。也有少数人每天虽排便2~3次,但粪便性状正常,则不能称为腹泻。腹泻一般是指每天大便次数增加或排便次数频繁,粪便稀薄或含有黏液脓血,或者还含有不消化的食物及其他病理性内容物。一般将腹泻分为急性腹泻与慢性腹泻两类,前者是指腹泻呈急性发病,历时短暂,而后者一般是指腹泻超过2个月。
症状体征:1.胃肠道症状 便意频繁,每次粪量不多并有里急后重感者,病变多在直肠或乙状结肠;小肠病变则无里急后重感。腹痛在下腹或左下腹,排便后腹痛可减轻者,往往为乙状结肠或直肠病变。小肠病变腹泻,疼痛多在脐周,排便后疼痛多不缓解。分泌性腹泻往往无腹痛症状。2.腹泻次数及粪便性状 急性腹泻每天排便可达10次以上,粪便多稀薄,如为细菌感染(细菌性痢疾)常带血及脓液。如为糖稀或果酱样粪便,提示可能是阿米巴痢疾。稀薄水样便常见于食物中毒。出血性坏死性肠炎排出洗肉水样血便,带有腥臭的气味。
目前,市场上收敛固脱的药物或是保健品有很多,但是大多数药物的效果并不是很好,并且大多数药物的副作用较多,会对人体健康造成伤害,保健品虽有一定的效果,但是其价格高昂,因此,市场上急需一种纯天然、无毒副作用的 橡实收敛固脱口服液及其制备方法。
发明内容
本发明的目的是提供一种橡实收敛固脱口服液及其制备方法,长期服用具有收敛固脱、止血、解毒的作用。
本发明的目的通过以下技术方案来实现:
一种橡实收敛固脱口服液,由原料按以下重量份数制备而成, 橡实35-45份、女儿红根10-15份、竹沥10-15份、没食子6-8份、枸骨叶6-8份、蘡薁根6-8份、油柑根3-5份、柚皮3-5份、榆白皮3-5份、榆叶3-5份、蜂蜜4-6份、蔗糖2-4份、白砂糖2-4份、木糖醇2-4份、柠檬酸1-3份、纯净水500份。
所述的一种橡实收敛固脱口服液,原料按优选重量份数, 橡实45份、女儿红根15份、竹沥15份、没食子7份、枸骨叶7份、蘡薁根7份、油柑根3份、柚皮3份、榆白皮3份、榆叶3份、蜂蜜6份、蔗糖3份、白砂糖3份、木糖醇2份、柠檬酸1份、纯净水500份。
所述的一种橡实收敛固脱口服液,原料按优选重量份数, 橡实40份、女儿红根13份、竹沥12份、没食子6份、枸骨叶6份、蘡薁根6份、油柑根5份、柚皮5份、榆白皮5份、榆叶5份、蜂蜜5份、蔗糖2份、白砂糖2份、木糖醇2份、柠檬酸1份、纯净水500份。
所述的一种橡实收敛固脱口服液,原料按优选重量份数, 橡实35份、女儿红根10份、竹沥10份、没食子8份、枸骨叶8份、蘡薁根8份、油柑根7份、柚皮7份、榆白皮7份、榆叶7份、蜂蜜4份、蔗糖4份、白砂糖4份、木糖醇4份、柠檬酸1份、纯净水500份。
所述的一种橡实收敛固脱口服液及其制备方法,其制备方法的主要步骤为:
a 、原料预处理:按重量份数,选取优质的 橡实、女儿红根、竹沥、没食子、枸骨叶、蘡薁根、油柑根、柚皮、榆白皮、榆叶,洗净并除杂,备用;
b 、粉碎:将洗净并除杂后的橡实、女儿红根、竹沥、没食子、枸骨叶、蘡薁根、油柑根、柚皮、榆白皮、榆叶分别置于超声波粉碎机中粉碎,过25目筛,备用;
c 、提取:将粉碎后的橡实、女儿红根、竹沥、没食子、枸骨叶、蘡薁根、油柑根、柚皮、榆白皮、榆叶混合搅拌均匀,加入8倍量乙醇中,浸泡8-12天,加热提取2次,每次1-1.5小时,得两次提取液和药渣,合并提取液;再将药渣加水煎煮两次,每次加入8-12倍的水,中火煎煮1.5-2小时,过滤,合并两次煎煮液;将合并后的提取液、合并后的煎煮液混合搅拌均匀,得混合液,备用;
d 、离心分离:取混合液,置于离心分离机中,4500r/min离心10-15分钟,得离心分离液;
e 、超滤:将离心分离液用分子量为6000-10000的超滤柱超滤,得超滤液;
f 、浓缩:将超滤液置于真空浓缩机中进行真空浓缩,得浓缩液;
g 、混合:按重量份数,选取优质的蜂蜜、蔗糖、白砂糖、木糖醇、柠檬酸,将蜂蜜、蔗糖、白砂糖、木糖醇、柠檬酸与浓缩液混合搅拌均匀,小火加热3-5分钟,加入纯净水,置于搅拌机中搅拌均匀,取出,采用紫外线灭菌,灭菌后分装成品,制得一种橡实收敛固脱口服液。
在药物中:橡实收敛固脱;止血;解毒;主泄泻痢疾;便血;痔血;脱肛;小儿疝气;疮痈久溃不乳腺炎;睾丸炎;女儿红根清热利湿;活血解毒;主热淋;黄疸;痢疾;带下;崩漏;跌打损伤;风湿疼痛;痈肿疮毒;竹沥清热豁痰,用于中风痰壅,肺热喘咳,热病烦躁;没食子固气,涩精,敛肺,止血;治大肠虚滑,泻痢不止,便血,遗精,阴汗,咳嗽,咯血,齿痛,创伤出血,疮疡久不收口;枸骨叶清热养阴,平肝,益肾;用于肺痨咯血,骨蒸潮热,头晕目眩;高血压;蘡薁根清湿热,消肿毒,治黄疸,湿痹,热淋,痢疾,肿毒,瘰疬,跌打损伤;油柑根清热,解毒,治腹泻,高血压,梅毒,下疳,蜈蚣咬伤;柚皮化痰,消食,下气,快膈,治气郁胸闷,脘腹冷痛,食滞,咳喘,疝气;榆白皮利水,通淋,消肿,治小便不通,淋浊,水肿,痈疽发背,丹毒,疥癣;榆叶清热利尿;安神;祛痰止咳;主水肿;小便不利;石淋;尿浊;失眠;暑热困闷;痰多咳嗽;酒(查皮)鼻
本发明的有益效果:本发明的橡实收敛固脱口服液,以祖传秘方为基础,精选橡实、女儿红根、竹沥、没食子、枸骨叶、蘡薁根、油柑根、柚皮、榆白皮、榆叶、等原料进行组合,使得各种药物的药效产生协同作用,从而能够达到效果,长期服用具有收敛固脱、止血、解毒的功效。
本发明经两组临床验证,其中一组为治疗组服用本发明,每天服用本发明一次,7天为一个疗程,另一组对照组服用 思密达 ,每天使用一次,7天为一个疗程,每组选择门诊病人60例,其中男30例,女30例,最大年龄75岁,最小年龄29岁,临床表现为泄泻痢疾,便血,痔血 ,表一为服用一个疗程后的对照数据:
表1服用前后两组疗程比较(单位:人)
治疗组和对照组有显著差异,从而可以看出本发明在临床上的应用有显著的疗效。
本发明的工艺优点在于:1、选择原料科学,生产工艺先进;2、产品中不添加香料及防腐剂,保持原料本身的风味和营养成份,易被人体吸收;3、原料来源广泛,加工艺线路短,产品易加工制造。
具体实施方式
实施例1
一种橡实收敛固脱口服液,由原料按以下重量份数制备而成, 橡实35-45份、女儿红根10-15份、竹沥10-15份、没食子6-8份、枸骨叶6-8份、蘡薁根6-8份、油柑根3-5份、柚皮3-5份、榆白皮3-5份、榆叶3-5份、蜂蜜4-6份、蔗糖2-4份、白砂糖2-4份、木糖醇2-4份、柠檬酸1-3份、纯净水500份。
实施例 2
一种橡实收敛固脱口服液,原料按优选重量份数, 橡实45份、女儿红根15份、竹沥15份、没食子7份、枸骨叶7份、蘡薁根7份、油柑根3份、柚皮3份、榆白皮3份、榆叶3份、蜂蜜6份、蔗糖3份、白砂糖3份、木糖醇2份、柠檬酸1份、纯净水500份。
实施例 3
一种橡实收敛固脱口服液,原料按优选重量份数, 橡实40份、女儿红根13份、竹沥12份、没食子6份、枸骨叶6份、蘡薁根6份、油柑根5份、柚皮5份、榆白皮5份、榆叶5份、蜂蜜5份、蔗糖2份、白砂糖2份、木糖醇2份、柠檬酸1份、纯净水500份。
实施例 4
一种橡实收敛固脱口服液,原料按优选重量份数, 橡实35份、女儿红根10份、竹沥10份、没食子8份、枸骨叶8份、蘡薁根8份、油柑根7份、柚皮7份、榆白皮7份、榆叶7份、蜂蜜4份、蔗糖4份、白砂糖4份、木糖醇4份、柠檬酸1份、纯净水500份。
实施例 5
一种橡实收敛固脱口服液及其制备方法,其制备方法的主要步骤为:
a 、原料预处理:按重量份数,选取优质的 橡实、女儿红根、竹沥、没食子、枸骨叶、蘡薁根、油柑根、柚皮、榆白皮、榆叶,洗净并除杂,备用;
b 、粉碎:将洗净并除杂后的橡实、女儿红根、竹沥、没食子、枸骨叶、蘡薁根、油柑根、柚皮、榆白皮、榆叶分别置于超声波粉碎机中粉碎,过25目筛,备用;
c 、提取:将粉碎后的橡实、女儿红根、竹沥、没食子、枸骨叶、蘡薁根、油柑根、柚皮、榆白皮、榆叶混合搅拌均匀,加入8倍量乙醇中,浸泡8-12天,加热提取2次,每次1-1.5小时,得两次提取液和药渣,合并提取液;再将药渣加水煎煮两次,每次加入8-12倍的水,中火煎煮1.5-2小时,过滤,合并两次煎煮液;将合并后的提取液、合并后的煎煮液混合搅拌均匀,得混合液,备用;
d 、离心分离:取混合液,置于离心分离机中,4500r/min离心10-15分钟,得离心分离液;
e 、超滤:将离心分离液用分子量为6000-10000的超滤柱超滤,得超滤液;
f 、浓缩:将超滤液置于真空浓缩机中进行真空浓缩,得浓缩液;
g 、混合:按重量份数,选取优质的蜂蜜、蔗糖、白砂糖、木糖醇、柠檬酸,将蜂蜜、蔗糖、白砂糖、木糖醇、柠檬酸与浓缩液混合搅拌均匀,小火加热3-5分钟,加入纯净水,置于搅拌机中搅拌均匀,取出,采用紫外线灭菌,灭菌后分装成品,制得一种橡实收敛固脱口服液。

Claims (5)

1.一种橡实收敛固脱口服液,其特征在于:由原料按以下重量份数制备而成,橡实35-45份、女儿红根10-15份、竹沥10-15份、没食子6-8份、枸骨叶6-8份、蘡薁根6-8份、油柑根3-5份、柚皮3-5份、榆白皮3-5份、榆叶3-5份、蜂蜜4-6份、蔗糖2-4份、白砂糖2-4份、木糖醇2-4份、柠檬酸1-3份、纯净水500份。
2.根据权利要求1所述的一种橡实收敛固脱口服液,其特征在于:原料按优选重量份数,橡实45份、女儿红根15份、竹沥15份、没食子7份、枸骨叶7份、蘡薁根7份、油柑根3份、柚皮3份、榆白皮3份、榆叶3份、蜂蜜6份、蔗糖3份、白砂糖3份、木糖醇2份、柠檬酸1份、纯净水500份。
3.根据权利要求1所述的一种橡实收敛固脱口服液,其特征在于:原料按优选重量份数,橡实40份、女儿红根13份、竹沥12份、没食子6份、枸骨叶6份、蘡薁根6份、油柑根5份、柚皮5份、榆白皮5份、榆叶5份、蜂蜜5份、蔗糖2份、白砂糖2份、木糖醇2份、柠檬酸1份、纯净水500份。
4.根据权利要求1所述的一种橡实收敛固脱口服液,其特征在于:原料按优选重量份数,橡实35份、女儿红根10份、竹沥10份、没食子8份、枸骨叶8份、蘡薁根8份、油柑根7份、柚皮7份、榆白皮7份、榆叶7份、蜂蜜4份、蔗糖4份、白砂糖4份、木糖醇4份、柠檬酸1份、纯净水500份。
5.根据权利要求1-4所述的一种橡实收敛固脱口服液及其制备方法,其特征在于:其制备方法的主要步骤为:
a、原料预处理:按重量份数,选取优质的橡实、女儿红根、竹沥、没食子、枸骨叶、蘡薁根、油柑根、柚皮、榆白皮、榆叶,洗净并除杂,备用;
b、粉碎:将洗净并除杂后的橡实、女儿红根、竹沥、没食子、枸骨叶、蘡薁根、油柑根、柚皮、榆白皮、榆叶分别置于超声波粉碎机中粉碎,过25目筛,备用;
c、提取:将粉碎后的橡实、女儿红根、竹沥、没食子、枸骨叶、蘡薁根、油柑根、柚皮、榆白皮、榆叶混合搅拌均匀,加入8倍量乙醇中,浸泡8-12天,加热提取2次,每次1-1.5小时,得两次提取液和药渣,合并提取液;再将药渣加水煎煮两次,每次加入8-12倍的水,中火煎煮1.5-2小时,过滤,合并两次煎煮液;将合并后的提取液、合并后的煎煮液混合搅拌均匀,得混合液,备用;
d、离心分离:取混合液,置于离心分离机中,4500r/min离心10-15分钟,得离心分离液;
e、超滤:将离心分离液用分子量为6000-10000的超滤柱超滤,得超滤液;
f、浓缩:将超滤液置于真空浓缩机中进行真空浓缩,得浓缩液;
g、混合:按重量份数,选取优质的蜂蜜、蔗糖、白砂糖、木糖醇、柠檬酸,将蜂蜜、蔗糖、白砂糖、木糖醇、柠檬酸与浓缩液混合搅拌均匀,小火加热3-5分钟,加入纯净水,置于搅拌机中搅拌均匀,取出,采用紫外线灭菌,灭菌后分装成品,制得一种橡实收敛固脱口服液。
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