CN106798971A - A kind of tumour radiotherapy experimental provision - Google Patents

A kind of tumour radiotherapy experimental provision Download PDF

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Publication number
CN106798971A
CN106798971A CN201710217196.3A CN201710217196A CN106798971A CN 106798971 A CN106798971 A CN 106798971A CN 201710217196 A CN201710217196 A CN 201710217196A CN 106798971 A CN106798971 A CN 106798971A
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CN
China
Prior art keywords
rotating shaft
experimental
lead
fixed plate
experimental provision
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710217196.3A
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Chinese (zh)
Inventor
于洪升
刘元伟
明洁
梁东海
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Affiliated Hospital of University of Qingdao
Original Assignee
Affiliated Hospital of University of Qingdao
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affiliated Hospital of University of Qingdao filed Critical Affiliated Hospital of University of Qingdao
Priority to CN201710217196.3A priority Critical patent/CN106798971A/en
Publication of CN106798971A publication Critical patent/CN106798971A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1077Beam delivery systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092Details
    • A61N2005/1094Shielding, protecting against radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092Details
    • A61N2005/1097Means for immobilizing the patient

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

The invention discloses a kind of tumour radiotherapy experimental provision, including experimental box and loading motion platform, case lid is provided with the top of the experimental box, the case lid is rotated with the experimental box and is connected, the madial wall of the case lid is provided with lead baffling barrel, the lead baffling barrel is fixed on the madial wall of the case lid, the bottom end face of the lead baffling barrel is provided with least two loopholes, X-ray emitter is provided with inside the lead baffling barrel, the relative two side wall of the experimental box is provided with the slide rail be arrangeding in parallel.The loophole set on lead baffling barrel of the present invention causes that X-ray can only irradiate the tumor locus of experimental animal by loophole, and the healthy body part of experimental animal can be covered by lead baffle plate, will not be irradiated by X-ray so that the precision of experimental data is improved.

Description

A kind of tumour radiotherapy experimental provision
Technical field
The present invention relates to medical health apparatus technical field, specially a kind of tumour radiotherapy experimental provision.
Background technology
Radiotherapy as treatment of cancer the significant means of a kind of curative effect and cost benefit, be combined therapy of tumour mistake Most important and indivisible part in journey.Accurate radiotherapy damages small advantage portion with its toxic and side effect and to patient Point instead of is previously the oncotherapy of essential therapeutic arsenals to perform the operation.
Radiation oncology subject high speed development, associated basic and clinic studies also fast development, pre- clinic in recent years Research is an indispensable ring in novel radiation treatment theoretical research, the electricity that the ionization radial line that mainly high-energy ray is produced is produced Damage larger from radiation normal tissue, theoretical research needed to be carried out in pre- clinical setting before human clinical trial is entered Fully checking, general checking needs zoopery to confirm.Experimental study is carried out most commonly by animal model for tumour is set up. It is experimental subjects to use meiofauna in experiment more, carries out tumour radiotherapy experiment, at present generally moves multiple in laboratory Thing receives X-ray simultaneously carries out Experiment on therapy.Mechanical system uses experimental stand structure, and tumor target essence is difficult to animal Certainly position, causes the actual dosage that receives of animal tissue not know, and the healthy position to meiofauna is irradiated, and causes to test number According to precision is high, confidence level is not high.
The content of the invention
It is an object of the invention to overcome above-mentioned technical problem, there is provided a kind of tumour radiotherapy experimental provision.
To achieve the above object, the present invention provides following technical scheme:
A kind of tumour radiotherapy experimental provision, including experimental box and loading motion platform, set at the top of the experimental box There is case lid, the case lid is rotated with the experimental box and is connected, and the madial wall of the case lid is provided with lead baffling barrel, the lead system Baffling barrel is fixed on the madial wall of the case lid, and the bottom end face of the lead baffling barrel is provided with least two loopholes, X-ray emitter is provided with inside the lead baffling barrel, the relative two side wall of the experimental box is provided with what is be arranged in parallel Slide rail, the loading motion platform includes fixed plate and animal fixing device, and the bottom of the fixed plate is connected with rotating shaft, described Rotating shaft drives the fixed plate rotation, and the two ends of the rotating shaft are separately positioned in the slide rail, and the rotating shaft is along the slide rail Level is slided.The loophole set on lead baffling barrel end face causes that X-ray can only irradiate the swollen of experimental animal by loophole Knurl position, and the healthy body part of experimental animal can be by the lighttight part masking of the end face of lead baffling barrel, will not Irradiated by X-ray so that the precision of experimental data is improved.Rotating shaft can drive fixed plate to be rotated, can be with The body inclination angle of regulation experiment animal;Rotating shaft is slided along slide rail level, and fixed plate can be driven to be put down in experimental box Move.
Further, square slider is provided with the slide rail, the square slider middle part is provided with circular hole, the two of the rotating shaft End is separately positioned in the circular hole.Square slider drives rotating shaft to be slided along slide rail level.
Further, brake gear is provided with one of them described square slider, the brake gear includes being arranged on The semicircle activity brake block of the side of the circular hole on the square slider and consolidating for the opposite side for being arranged on the circular hole Determine block, one end of the semicircle activity brake block is flexibly connected with the square slider, the semicircle activity brake block The other end is detachably connected by bolt with the fixed block.By setting brake gear, can control between rotating shaft and circular hole Rotation, brake gear is opened when axis of rotation is needed, when axis of rotation is not needed, then by semicircle activity brake block and Fixed block block is bolted and just can prevent together rotating shaft and voluntarily rotate.
Further, one end of the rotating shaft is provided with knob.By knob rotating shaft, so as to drive fixed plate to be revolved Turn.
Further, the height of the height less than the casing back side panel of the front side board of the experiment box body.It is convenient to The operation such as meiofauna is placed in case.
Further, the case lid is articulated and connected with the top margin of the back side panel of the experimental box by rotating shaft.
Further, each side of the experimental box is respectively stainless steel and stereotype superposition is constituted.Experiment box structure jail Gu, it is possible to protect X-ray to pollute outside.
Further, the animal fixing device includes at least four arc locating rings, one end of the arc locating ring Rotated with the fixed plate and be connected, the fixed plate is provided with circular draw-in groove, the other end and the circle of the arc locating ring Shape draw-in groove is snapped connection.
Further, the circular draw-in groove includes the circular groove being arranged in the fixed plate, the circular groove Madial wall is provided with annular projection, and the other end of the arc locating ring is provided with the elastic card coordinated with the circular draw-in groove Block, the elastic clamping block includes, in two flexure strips of del, arc groove being provided with the middle part of the flexure strip.By falling The flexure strip of triangle is buckled in circular draw-in groove, and the arc groove on flexure strip is buckled in the annulus on circular groove madial wall In shape projection.When using, two flexure strips of del are snapped into circular draw-in groove, when needing to untie arc retainer ring When, two flexure strips are clutched with finger, the arc groove on flexure strip is separated with annular projection, you can by arc locating ring With circular exact separation.
Further, the fixed plate is provided with latex film.So that fixed plate is preferably fitted with experimental animal limbs, with Radiation and refraction of the interface to X-ray are reduced, while the flexibility of latex film is good, the bad thorn to experimental animal limbs is reduced Swash.
Further, the box inside wall is provided with illuminating lamp.Illuminating lamp is used for being illuminated in experimental box, convenient Fixation to experimental animal etc. is operated.
Compared with prior art, beneficial effects of the present invention are as follows:
1st, the loophole set on lead baffling barrel of the present invention causes that X-ray can only irradiate experimental animal by loophole Tumor locus, and the healthy body part of experimental animal can be covered by lead baffle plate, will not be irradiated by X-ray, make The precision for obtaining experimental data is improved.
2nd, rotating shaft of the present invention can drive fixed plate to be rotated, can be with the body inclination angle of regulation experiment animal;Turn Axle is slided along slide rail level, and fixed plate can be driven to be translated in experimental box.
3rd, the arc locating ring on animal fixing device of the present invention is buckled in draw-in groove by the flexure strip of del, is made Used time, two flexure strips of del are snapped into circular draw-in groove, when needing to untie arc retainer ring, are clutched with finger Two flexure strips, make the arc groove on flexure strip be separated with annular projection, you can by arc locating ring and exact separation, can To realize the purpose of quick fixed experimental animal and quick separating experimental animal.
Brief description of the drawings
Fig. 1 is structural representation of the invention;
Fig. 2 is the structural representation of rotating shaft of the present invention and square slider;
Fig. 3 is the structural representation of animal fixing device of the present invention.
In figure:1 experimental box, 2 front side boards, 3 back side panels, 4 case lids, 5 lead baffling barrels, 6 loopholes, 7X ray emitters, 8 Slide rail, 9 square sliders, 10 circular holes, 11 semicircle activity brake blocks, 12 fixed blocks, 13 bolts, 14 rotating shafts, 15 knobs, 16 are fixed Plate, 17 latex films, 18 arc locating rings, 19 circular grooves, 20 annulars are convex, 21 flexure strips.
Specific embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete Site preparation is described, it is clear that described embodiment is only a part of embodiment of the invention, rather than whole embodiments.It is based on Embodiment in the present invention, it is every other that those of ordinary skill in the art are obtained under the premise of creative work is not made Embodiment, belongs to the scope of protection of the invention.
As shown in Figure 1, Figure 2 and Figure 3, a kind of tumour radiotherapy experimental provision, including experimental box 1 and loading campaign are flat Platform, the height of the height less than casing back side panel 3 of the front side board 2 of the casing of experimental box 1.The top of the back side panel 3 of case lid 4 and experimental box While being articulated and connected by rotating shaft.Each side of experimental box is respectively stainless steel and stereotype superposition is constituted, experimental box box inside Wall is provided with illuminating lamp.
The madial wall of case lid 4 is provided with lead baffling barrel 5, and lead baffling barrel 5 is fixed on the madial wall of case lid 4, lead system The bottom end face of baffling barrel 5 is provided with least two loopholes 6, and X-ray emitter 7, experimental box are provided with inside lead baffling barrel 5 1 relative two side wall is provided with and square slider 9 is provided with the slide rail 8 be arrangeding in parallel, slide rail 8, and the middle part of square slider 9 is provided with Circular hole 10, the two ends of rotating shaft 14 are separately positioned in circular hole 10, and brake gear is provided with one of square slider 9, brake Device includes the semicircle activity brake block 11 of the side of the circular hole 10 being arranged on square slider 9 and is arranged on the another of circular hole 10 The fixed block 12 of side, one end of semicircle activity brake block 11 is flexibly connected with square slider 9, semicircle activity brake block 11 The other end be detachably connected with fixed block 12 by bolt 13.By setting brake gear, rotating shaft 14 and circular hole can be controlled Rotation between 10, brake gear is opened when needing rotating shaft 14 to rotate, when not needing rotating shaft 14 to rotate, then semicircle is living Linked together by bolt 13 rotating shaft 14 that just can prevent of 12 pieces of dynamic brake block 11 and fixed block is voluntarily rotated.One end of rotating shaft 14 Knob 15 is provided with, by the rotating shaft 14 of knob 15, so as to drive fixed plate 16 to be rotated.
Loading motion platform includes fixed plate 16 and animal fixing device, and the bottom of fixed plate 16 is connected with rotating shaft 14, turns Axle 14 drives fixed plate 16 to rotate, and the two ends of rotating shaft 14 are separately positioned in slide rail 8, and rotating shaft 14 is slided along the level of slide rail 14.Gu Fixed board 16 is provided with latex film 17.So that fixed plate 16 is preferably fitted with experimental animal limbs, to reduce interface to X-ray Radiation and refraction, while the flexibility of latex film 17 is good, reduce the pessimal stimulation to experimental animal limbs.
Animal fixing device includes at least four arc locating rings 18, and one end and the fixed plate 16 of arc locating ring 18 are rotated Connection, fixed plate 16 is provided with circular draw-in groove, and the other end of arc locating ring 18 is snapped connection with circular draw-in groove.Circular draw-in groove bag The circular groove 19 being arranged in fixed plate 16 is included, the madial wall of circular groove 19 is provided with annular projection 20, arc positioning The other end of ring 18 is provided with the elastic clamping block coordinated with circular draw-in groove 19, and elastic clamping block is included in two flexure strips of del 21, the middle part of flexure strip 21 is provided with arc groove 22.It is buckled in circular draw-in groove by the flexure strip 21 of del, flexure strip On convex 20 of the annular that arc groove 22 on 21 is buckled on circular groove madial wall.
When using, experimental animal is prevented in fixed plate 16, two flexure strips 21 of del are snapped into circle In draw-in groove 19, the four limbs of experimental animal are fixed in fixed plate 16 by arc locating ring 18, are fixed when needing to untie arc During ring 18, two flexure strips 21 are clutched with finger, the arc groove 19 on flexure strip 21 is separated with annular projection 20, you can By arc locating ring 18 and circular exact separation.Rotating shaft 14 drives fixed plate 16 to be rotated, with the body of regulation experiment animal Angle of inclination;Rotating shaft 14 is slided along the level of slide rail 8, drives the tumor locus of the experimental animal in fixed plate 16 to be directed at X-ray Irradiated site.
Case lid 4 is covered, X-ray emitter 7 is opened, the loophole 6 set on the end face of lead baffling barrel 5 causes X-ray only The tumor locus of experimental animal can be irradiated by loophole 6, and the healthy body part of experimental animal can be in the light by lead system The lighttight part masking of end face of cylinder, will not be irradiated so that the precision of experimental data is improved by X-ray.
Although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with Understanding can carry out various changes, modification, replacement to these embodiments without departing from the principles and spirit of the present invention And modification, the scope of the present invention be defined by the appended.

Claims (10)

1. a kind of tumour radiotherapy experimental provision, it is characterised in that:Including experimental box and loading motion platform, the experimental box Top be provided with case lid, the case lid is rotated with the experimental box and is connected, and the madial wall of the case lid is provided with lead baffling barrel, The lead baffling barrel is fixed on the madial wall of the case lid, and the bottom end face of the lead baffling barrel is provided with least two Loophole, is provided with X-ray emitter inside the lead baffling barrel, the relative two side wall of the experimental box is provided with parallel The slide rail of setting;
The loading motion platform includes fixed plate and animal fixing device, and the bottom of the fixed plate is connected with rotating shaft, described Rotating shaft drives the fixed plate rotation, and the two ends of the rotating shaft are separately positioned in the slide rail, and the rotating shaft is along the slide rail Level is slided.
2. a kind of tumour radiotherapy experimental provision according to claim 1, it is characterised in that:The side of being provided with the slide rail Shape sliding block, the square slider middle part is provided with circular hole, and the two ends of the rotating shaft are separately positioned in the circular hole.
3. a kind of tumour radiotherapy experimental provision according to claim 2, it is characterised in that:, one of them described side Brake gear is provided with shape sliding block, the brake gear includes the side of the circular hole being arranged on the square slider The fixed block of semicircle activity brake block and the opposite side for being arranged on the circular hole, one end of the semicircle activity brake block with The square slider is flexibly connected, and the other end of the semicircle activity brake block is detachably connected by bolt with the fixed block Connect.
4. a kind of tumour radiotherapy experimental provision according to claim 3, it is characterised in that:One end of the rotating shaft sets There is knob.
5. a kind of tumour radiotherapy experimental provision according to claim 1, it is characterised in that:The experiment box body Height of the height of front side board less than the casing back side panel.
6. a kind of tumour radiotherapy experimental provision according to claim 5, it is characterised in that:The case lid and the reality The top margin of the back side panel of tryoff is articulated and connected by rotating shaft.
7. a kind of tumour radiotherapy experimental provision according to claim 1, it is characterised in that:Each of the experimental box Side is respectively stainless steel and stereotype superposition is constituted.
8. a kind of tumour radiotherapy experimental provision according to claim 1, it is characterised in that:The animal fixing device Including at least four arc locating rings, one end of the arc locating ring rotates with the fixed plate and is connected, in the fixed plate Circular draw-in groove is provided with, the other end of the arc locating ring is snapped connection with the circular draw-in groove.
9. a kind of tumour radiotherapy experimental provision according to claim 8, it is characterised in that:The circular draw-in groove includes The circular groove in the fixed plate is arranged on, the madial wall of the circular groove is provided with annular projection, and the arc is determined The other end of position ring is provided with the elastic clamping block coordinated with the circular draw-in groove, and the elastic clamping block includes two in del Flexure strip, arc groove is provided with the middle part of the flexure strip.
10. a kind of tumour radiotherapy experimental provision according to claim 1, it is characterised in that:Set in the fixed plate There is latex film.
CN201710217196.3A 2017-04-05 2017-04-05 A kind of tumour radiotherapy experimental provision Pending CN106798971A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710217196.3A CN106798971A (en) 2017-04-05 2017-04-05 A kind of tumour radiotherapy experimental provision

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710217196.3A CN106798971A (en) 2017-04-05 2017-04-05 A kind of tumour radiotherapy experimental provision

Publications (1)

Publication Number Publication Date
CN106798971A true CN106798971A (en) 2017-06-06

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Country Status (1)

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Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007055501A1 (en) * 2005-11-11 2007-05-18 Drgem Corporation Multi purpose x-ray micro ct scanner
CN203591284U (en) * 2013-12-12 2014-05-14 陈雅隽 Rabbit dissecting table used for physiological experiment teaching
CN104126516A (en) * 2014-08-12 2014-11-05 浙江省肿瘤医院 Radiobiological functional experiment box
CN104257439A (en) * 2014-10-28 2015-01-07 沈阳医学院 Enclosed animal experiment operation box
CN204169949U (en) * 2014-07-23 2015-02-25 浙江省肿瘤医院 Radiation biological experiment acra locate mode fixed support
CN104983483A (en) * 2015-07-16 2015-10-21 代亮 Multifunctional rodent fixator and use method thereof
CN105156954A (en) * 2015-10-09 2015-12-16 中国科学院西北高原生物研究所 Light irradiation device used for establishment of experimental animal skin injury model
CN204971691U (en) * 2015-07-16 2016-01-20 代亮 Multi -functional rodent fixer
KR20170002107A (en) * 2015-06-29 2017-01-06 정영자 X-ray shield apparatus for an animal hospital

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007055501A1 (en) * 2005-11-11 2007-05-18 Drgem Corporation Multi purpose x-ray micro ct scanner
CN203591284U (en) * 2013-12-12 2014-05-14 陈雅隽 Rabbit dissecting table used for physiological experiment teaching
CN204169949U (en) * 2014-07-23 2015-02-25 浙江省肿瘤医院 Radiation biological experiment acra locate mode fixed support
CN104126516A (en) * 2014-08-12 2014-11-05 浙江省肿瘤医院 Radiobiological functional experiment box
CN104257439A (en) * 2014-10-28 2015-01-07 沈阳医学院 Enclosed animal experiment operation box
KR20170002107A (en) * 2015-06-29 2017-01-06 정영자 X-ray shield apparatus for an animal hospital
CN104983483A (en) * 2015-07-16 2015-10-21 代亮 Multifunctional rodent fixator and use method thereof
CN204971691U (en) * 2015-07-16 2016-01-20 代亮 Multi -functional rodent fixer
CN105156954A (en) * 2015-10-09 2015-12-16 中国科学院西北高原生物研究所 Light irradiation device used for establishment of experimental animal skin injury model

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