CN1067553C - Oyster extract and method for preparing its prepn. - Google Patents

Oyster extract and method for preparing its prepn. Download PDF

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Publication number
CN1067553C
CN1067553C CN94101124A CN94101124A CN1067553C CN 1067553 C CN1067553 C CN 1067553C CN 94101124 A CN94101124 A CN 94101124A CN 94101124 A CN94101124 A CN 94101124A CN 1067553 C CN1067553 C CN 1067553C
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CN
China
Prior art keywords
preparation
extract
concha ostreae
taurine
present
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Expired - Lifetime
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CN94101124A
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Chinese (zh)
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CN1106264A (en
Inventor
王克
孔徐生
黄山平
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Haiwang Group Co ltd Shenzhen
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Haiwang Group Co ltd Shenzhen
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Priority to CN94101124A priority Critical patent/CN1067553C/en
Publication of CN1106264A publication Critical patent/CN1106264A/en
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Publication of CN1067553C publication Critical patent/CN1067553C/en
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Expired - Lifetime legal-status Critical Current

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Abstract

The present invention relates to a method for extracting effective active components from fresh live oyster shells, which comprises the steps of water extraction, filtration, vacuum concentration, spray-drying, etc. The present invention also relates to an oyster shell extractive obtained by the method, and the oyster shell extractive contains 0.1 to 10 wt% of taurine and 10 to 50 wt% of glycogen. The present invention further relates to an oyster shell extractive preparation which contains 4 to 10 wt% of taurine.

Description

The preparation method of Concha Ostreae extract and preparation thereof
The present invention relates to a kind of method of effective active nutritional labeling and active substance that extracts with this method thereof of from bright Concha Ostreae, extracting.
Concha Ostreae is a shell-fish, is grown in the ocean.Concha Ostreae is as traditional Chinese crude drug, the detailed record that has in for pharmacopeia in Ancient Chinese, as just pointing out in detail once in Compendium of Material Medica, Shennong's Herbal that Concha Ostreae was to nourish to keep fit good merchantable brand, be to record and narrate like this in the Compendium of Material Medica: Carnis ostreae " control deficient, transfer in, separate erysipelas, mend dysphoria with smothery sensation after married woman's vim and vigour, the rice wine, quench the thirst, make us thin skin, U.S. color ".
In the Chinese medicine medical material, mainly be that the shell with Concha Ostreae is used as medicine.Limited the application of Concha Ostreae significantly as medical material and health product.
Carnis ostreae all is one delicious and famous and precious dish in China and foreign countries, and occupying in dietetic therapy, tonic has consequence, as the effect of being recorded and narrated in the Compendium of Material Medica.These effects of Carnis ostreae; mainly be because contain distinctive bioactive substance in a large amount of taurines, glycogen and the marine organisms in the Carnis ostreae; in addition, also contain whole aminoacid of needed by human, trace element that abundant and ratio is suitable such as zinc, ferrum, copper, sulphur, selenium etc.
In sum, first purpose of the present invention will provide a kind of method exactly, extracts the effective ingredient of Carnis ostreae, can utilize it easily and effectively.
Second purpose of the present invention provides a kind of extract that contains effective ingredient in the Carnis ostreae.
The 3rd purpose of the present invention provides a kind of preparation that contains effective component extracts in the Carnis ostreae.
Extracting method of the present invention comprises the steps:
1) fresh and alive Concha Ostreae is shelled, the washing roguing;
2) at 1-5Kgf/cm 2Use water extraction under the temperature of the pressure of (kilogram) (gauge pressure) and 40 ℃-110 ℃, extraction time is 1-3 time, preferred secondary, and each 0.5-2 hour, institute's water can be deionized water, distilled water, and the weight ratio of Carnis ostreae and water is 1: 1~1: 3, is preferably 1: 2;
3) filter, remove residue;
4) concentrating under reduced pressure in a vacuum, just Be10-12;
5) carry out the spray painting drying in spray dryer, exsiccant instantaneous temperature is 160-190 ℃, and outlet temperature is 85-100 ℃, promptly gets Concha Ostreae extract of the present invention.
By analysis, contain taurine 0.1-10wt% in the said extracted thing, glycogen 10-50wt%, each seed amino acid and various trace elements.This extract can be used as treatment or the medicine of auxiliary treatment and the raw material that health product or medicine are made in conduct of health product, chronic disease.
The invention still further relates to more than one and state the preparation that extract is a feedstock production.Said preparation adds a certain amount of taurine in extract, to 4-10wt%, strengthen its effect with the content that improves taurine in the extract.Usually, its adding proportion is that the weight ratio of extract and taurine is 10: 1~5: 1, preferred 8: 1.Be appreciated that except that taurine, can also add other auxiliary element,,, can add distilled water or deionized water,, can add excipient, as magnesium stearate etc. for making tablet, capsule etc. for increasing its operation, processing characteristics as starch, sugar.
Improved extract of the present invention can be used as the patent medicine of treatment or the multiple chronic disease of auxilliary treatment, or as the health product of nourishing and fit keeping function.It all has obvious curative effects to chronic hepatitis, hyperlipidemia, tumor, tuberculosis, neurasthenia, diabetes, ICVD, obstetrical and gynecological disease, and can improve people's immune function.
Be the concrete preparation program of preparation of the present invention below.Its objective is a kind of tablet or capsule that contains Concha Ostreae extract and taurine of preparation, general, take 1-5 sheet or grain as required every day.Take Concha Ostreae extract 0.2-2.0g preferred every day, and it is as follows specifically to fill a prescription:
Concha Ostreae extract: 40-70 part (weight)
Taurine: 4-10 part (weight)
Starch: 10-20 part (weight)
Other adjuvant: 0-5 part (weight) adjuvant described here is magnesium stearate, sugar etc.Preparation by above-mentioned formulated can be directly used in treatment or the various chronic diseases of auxiliary treatment, or as health care patent medicine.
Aspect the liver protecting human body immunity improving power, said preparation can improve the chronic hepatitis patient clinical symptoms rapidly, promotes rehabilitation, and its total effective rate is more than 68% (P<0.05).Aspect the auxiliary treatment of tumor, can obviously alleviate the side effect due to radiotherapy, the chemotherapy, alleviate the bone marrow depression state, be more than 80% to leukopenia person's total effective rate after radiotherapy, the chemotherapy; Effect aspect blood fat reducing is also fairly obvious, and wherein the total effective rate of cholesterol reducing is 77.9%, and reducing B-lipoprotein effective percentage is 78%, and the triglyceride reducing effective percentage is 76.3%; Said preparation can also obviously improve neurasthenia symptom, and its effective percentage is 87.5%, and in addition, this kind preparation can also impel puerpera to lactate, increases the content of SIgA in the breast milk, and promotes puerpera's postpartum recovery.Said preparation protects the liver, helps the effect of wine in addition.

Claims (4)

1. the method that from bright Concha Ostreae, prepares the active ingredient extract, this method comprises extracting in water in the bright Concha Ostreae of shelling, filter then and the condensed water extract, final drying is handled and is obtained solid-state effective ingredient, is characterised in that wherein said water extraction step is to carry out 0.5 to 2 hour under 1-5 kilogram pressure and 40-110 ℃ of temperature.
2. the solids extraction thing that contains the Concha Ostreae active ingredient that makes according to the method for claim 1.
3. the preparation that contains Concha Ostreae extract is characterised in that and wherein contains Concha Ostreae extract and the 4-10 weight portion taurine of 40-70 weight portion by the method preparation of claim 1.
4. according to the preparation of claim 3, be characterised in that wherein said preparation is tablet or capsule form.
CN94101124A 1994-02-02 1994-02-02 Oyster extract and method for preparing its prepn. Expired - Lifetime CN1067553C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN94101124A CN1067553C (en) 1994-02-02 1994-02-02 Oyster extract and method for preparing its prepn.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN94101124A CN1067553C (en) 1994-02-02 1994-02-02 Oyster extract and method for preparing its prepn.

Publications (2)

Publication Number Publication Date
CN1106264A CN1106264A (en) 1995-08-09
CN1067553C true CN1067553C (en) 2001-06-27

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CN94101124A Expired - Lifetime CN1067553C (en) 1994-02-02 1994-02-02 Oyster extract and method for preparing its prepn.

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Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1085531C (en) * 1994-06-23 2002-05-29 深圳海王药业有限公司 Preparation for protecting liver and relieving acute alcoholism and its preparing method
CN100358439C (en) * 2002-12-11 2008-01-02 张之中 Deep processing method for producing serial oyster products
JP2006327996A (en) * 2005-05-27 2006-12-07 Sonoko:Kk Medicine or functional food for controlling elevation of glycemia
CN103584249B (en) * 2012-08-14 2016-03-23 海沃企业管理(昆明)有限公司 A kind of oyster powder solid beverage and production technology thereof
CN103519112A (en) * 2013-10-17 2014-01-22 厦门洋江食品有限公司 Method for concentrating oyster juice
CN103610056A (en) * 2013-11-30 2014-03-05 大连润扬科技发展有限公司 Capsule for neurastheniac and production process of capsule

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1055650A (en) * 1991-04-22 1991-10-30 中山大学 The production method of full-nourishment oyster powder
CN1075259A (en) * 1993-01-13 1993-08-18 陈敬文 Medical active calcium and its manufacture method
CN1080486A (en) * 1992-07-01 1994-01-12 天津医学院 Xin oyster nature nutrition oral liquid and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1055650A (en) * 1991-04-22 1991-10-30 中山大学 The production method of full-nourishment oyster powder
CN1080486A (en) * 1992-07-01 1994-01-12 天津医学院 Xin oyster nature nutrition oral liquid and preparation method thereof
CN1075259A (en) * 1993-01-13 1993-08-18 陈敬文 Medical active calcium and its manufacture method

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
《中国海洋要物》(1) 1994.1.31 "金牡蛎"治疗高脂血症的临床观察 *
《中国海洋要物》(1) 1994.1.31 "金牡蛎"治疗高脂血症的临床观察;《中国海洋要物》(4) 1991.4.30 林钧明牡蛎肉中牛磺酸的研究近况;《中国海洋要物》10(1) 1991.1.31 王顺年等 牡蛎肉有关化学成分的研究 *
《中国海洋要物》(4) 1991.4.30 林钧明牡蛎肉中牛磺酸的研究近况 *
《中国海洋要物》10(1) 1991.1.31 王顺年等 牡蛎肉有关化学成分的研究 *

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