CN106729196A - A kind of granatum relieving diarrhea with astringents lozenge and its production method - Google Patents
A kind of granatum relieving diarrhea with astringents lozenge and its production method Download PDFInfo
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- CN106729196A CN106729196A CN201510820469.4A CN201510820469A CN106729196A CN 106729196 A CN106729196 A CN 106729196A CN 201510820469 A CN201510820469 A CN 201510820469A CN 106729196 A CN106729196 A CN 106729196A
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- China
- Prior art keywords
- parts
- granatum
- astringents
- lozenge
- compressing tablet
- Prior art date
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- 206010012735 Diarrhoea Diseases 0.000 title claims abstract description 26
- 239000007937 lozenge Substances 0.000 title claims abstract description 25
- 239000003212 astringent agent Substances 0.000 title claims abstract description 22
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 13
- 239000003826 tablet Substances 0.000 claims abstract description 31
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 26
- 239000002994 raw material Substances 0.000 claims abstract description 21
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 19
- 229920002472 Starch Polymers 0.000 claims abstract description 19
- 229940084030 carboxymethylcellulose calcium Drugs 0.000 claims abstract description 19
- 239000008103 glucose Substances 0.000 claims abstract description 19
- 239000008107 starch Substances 0.000 claims abstract description 19
- 235000019698 starch Nutrition 0.000 claims abstract description 19
- 241000218202 Coptis Species 0.000 claims abstract description 14
- 235000002991 Coptis groenlandica Nutrition 0.000 claims abstract description 14
- 241000830535 Ligustrum lucidum Species 0.000 claims abstract description 14
- 241000220317 Rosa Species 0.000 claims abstract description 14
- 241000219784 Sophora Species 0.000 claims abstract description 14
- 241000605422 Asparagus asparagoides Species 0.000 claims abstract description 13
- 238000001035 drying Methods 0.000 claims abstract description 13
- 230000036541 health Effects 0.000 claims abstract description 7
- 238000002156 mixing Methods 0.000 claims abstract description 7
- 238000004806 packaging method and process Methods 0.000 claims abstract description 7
- 239000000843 powder Substances 0.000 claims abstract description 7
- 239000000706 filtrate Substances 0.000 claims description 12
- 238000000034 method Methods 0.000 claims description 10
- 230000008569 process Effects 0.000 claims description 7
- 239000012535 impurity Substances 0.000 claims description 6
- 239000011812 mixed powder Substances 0.000 claims description 6
- 235000014347 soups Nutrition 0.000 claims description 4
- 238000001914 filtration Methods 0.000 claims description 3
- -1 packaging Substances 0.000 claims description 3
- 238000003825 pressing Methods 0.000 claims description 3
- 238000001694 spray drying Methods 0.000 claims description 3
- 239000003643 water by type Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 abstract description 7
- 230000000694 effects Effects 0.000 abstract description 7
- 239000004480 active ingredient Substances 0.000 abstract description 4
- 230000008901 benefit Effects 0.000 abstract description 3
- 231100000957 no side effect Toxicity 0.000 abstract description 3
- 230000001228 trophic effect Effects 0.000 abstract description 2
- 239000008280 blood Substances 0.000 description 8
- 210000004369 blood Anatomy 0.000 description 8
- 208000035861 hematochezia Diseases 0.000 description 6
- 208000002193 Pain Diseases 0.000 description 5
- 206010046788 Uterine haemorrhage Diseases 0.000 description 5
- 208000001848 dysentery Diseases 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- 206010007247 Carbuncle Diseases 0.000 description 4
- 208000012287 Prolapse Diseases 0.000 description 4
- 210000000436 anus Anatomy 0.000 description 4
- 208000019902 chronic diarrheal disease Diseases 0.000 description 4
- 230000023597 hemostasis Effects 0.000 description 4
- 208000004998 Abdominal Pain Diseases 0.000 description 3
- 206010017553 Furuncle Diseases 0.000 description 3
- 210000000988 bone and bone Anatomy 0.000 description 3
- 230000008602 contraction Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 208000003512 furunculosis Diseases 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 210000003205 muscle Anatomy 0.000 description 3
- 201000004647 tinea pedis Diseases 0.000 description 3
- 206010000087 Abdominal pain upper Diseases 0.000 description 2
- 208000032843 Hemorrhage Diseases 0.000 description 2
- 206010047700 Vomiting Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 230000000202 analgesic effect Effects 0.000 description 2
- 208000034158 bleeding Diseases 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 208000014617 hemorrhoid Diseases 0.000 description 2
- 206010033675 panniculitis Diseases 0.000 description 2
- 244000045947 parasite Species 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 210000000697 sensory organ Anatomy 0.000 description 2
- 210000004304 subcutaneous tissue Anatomy 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- 238000012795 verification Methods 0.000 description 2
- 230000008673 vomiting Effects 0.000 description 2
- 208000004429 Bacillary Dysentery Diseases 0.000 description 1
- 241000244203 Caenorhabditis elegans Species 0.000 description 1
- 208000031973 Conjunctivitis infective Diseases 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 206010013954 Dysphoria Diseases 0.000 description 1
- 206010017915 Gastroenteritis shigella Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 206010019909 Hernia Diseases 0.000 description 1
- 208000031361 Hiccup Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 208000015817 Infant Nutrition disease Diseases 0.000 description 1
- 208000037093 Menstruation Disturbances Diseases 0.000 description 1
- 206010027339 Menstruation irregular Diseases 0.000 description 1
- 201000005702 Pertussis Diseases 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 241000362909 Smilax <beetle> Species 0.000 description 1
- 208000037386 Typhoid Diseases 0.000 description 1
- 206010000269 abscess Diseases 0.000 description 1
- 201000001028 acute contagious conjunctivitis Diseases 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000003474 anti-emetic effect Effects 0.000 description 1
- 239000002111 antiemetic agent Substances 0.000 description 1
- 208000002399 aphthous stomatitis Diseases 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000009045 body homeostasis Effects 0.000 description 1
- 239000006189 buccal tablet Substances 0.000 description 1
- 229940046011 buccal tablet Drugs 0.000 description 1
- 230000009172 bursting Effects 0.000 description 1
- 239000007891 compressed tablet Substances 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000002996 emotional effect Effects 0.000 description 1
- 206010015037 epilepsy Diseases 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 210000003128 head Anatomy 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 244000000053 intestinal parasite Species 0.000 description 1
- 201000005630 leukorrhea Diseases 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 201000007227 lymph node tuberculosis Diseases 0.000 description 1
- 208000004396 mastitis Diseases 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 201000005737 orchitis Diseases 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 201000005113 shigellosis Diseases 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 208000024794 sputum Diseases 0.000 description 1
- 210000003802 sputum Anatomy 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 208000003265 stomatitis Diseases 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 208000006379 syphilis Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 201000008297 typhoid fever Diseases 0.000 description 1
- 206010046901 vaginal discharge Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/638—Ligustrum, e.g. Chinese privet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/90—Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
Abstract
A kind of granatum relieving diarrhea with astringents lozenge and its production method.By granatum, smilax, the coptis, rose, sophora flower, caulis bambusae in taenian, acorn, glossy privet leaf, carboxymethylcellulose calcium,
Water soluble starch,
Glucose
Constituted Deng raw material, finished product is made by sorting, drying, decoction, mixing, powder processed, compressing tablet, packaging.
Active ingredient in Chinese medicine is decocted and is made extract solution by the present invention, active ingredient is combined with lozenge, the nutriment in the Chinese medicine being effectively kept；By the proportioning of science, when product of the present invention is nourished human body, with mending without dry, trophic structure rationally, strengthens effect of human body constitution.The present invention
Have
Health care, relieving diarrhea with astringents, pure natural, pollution-free, no side effectses, the advantages of conveniently take and nourish the body.
Description
Technical field：
The present invention relates to technical field of food healthcare, and in particular to a kind of granatum relieving diarrhea with astringents lozenge and its production method.
Background technology
Buccal tablet refers to the compressed tablets for being contained in slow mechanism dissolved in oral cavity, and lozenge will have tempting color from inside to outside, so that the mouthfeel that user has had.Therefore, the figuration composition in lozenge, such as sugar, pigment additive often " a presumptuous guest usurps the role of the host " so that some by mistake lozenge is regarded as " sugar ".
At present, most of lozenge of in the market is all medicine, and most of medicines for being to treat Throat diseases, and narrow application range, therapeutic effect is general.And it is few using the utilization rate for being processed into health products containing chip technology, it is few to body-care effect, it is impossible to meet the market demand.
The content of the invention：
It is an object of the invention to provide one kind collection relieving diarrhea with astringents, it is pure natural, pollution-free,
No side effectses are conveniently taken and are nourished the body in one
Granatum relieving diarrhea with astringents lozenge and production method.
The object of the present invention is achieved like this.It is that the raw material matched somebody with somebody by following weight is made,
Granatum
15-30
Part, smilax
10-20
Part, the coptis
5-15
Part, rose
3-15
Part, sophora flower
3-15
Part, caulis bambusae in taenian
3-10
Part, acorn
4-12
Part, glossy privet leaf
6-9
Part, carboxymethylcellulose calcium
7-10
Part, water soluble starch
4-8
Part, glucose
10-15
Part.
Preparing granatum relieving diarrhea with astringents lozenge preferred weight ratio range of the present invention is,
Granatum
15-25
Part, smilax
10-15
Part, the coptis
5-12
Part, rose
3-10
Part, sophora flower
3-10
Part, caulis bambusae in taenian
3-8
Part, acorn
4-10
Part, glossy privet leaf
6-8
Part, carboxymethylcellulose calcium
7-9
Part, water soluble starch
4-7
Part, glucose
10-14
Part.
Preparing granatum relieving diarrhea with astringents lozenge best weight ratio scope of the present invention is,
Granatum
20
Part, smilax
12
Part, the coptis
10
Part, rose
8
Part, sophora flower
8
Part, caulis bambusae in taenian
5
Part, acorn
8
Part, glossy privet leaf
7
Part, carboxymethylcellulose calcium
8
Part, water soluble starch
6
Part, glucose
12
Part.
Above-mentioned each component is made the production method of granatum relieving diarrhea with astringents lozenge of the present invention, technical process is：
Sorting, drying, decoction, mixing, powder processed, compressing tablet, packaging, concrete operation method follow these steps to successively：
A
, sorting, by raw material weight proportioning of soup processed, select meet the granatum of national health and quality standard, smilax, the coptis, rose, sophora flower, caulis bambusae in taenian, acorn, glossy privet leaf, carboxymethylcellulose calcium,
Water soluble starch,
Glucose feed is standby；
B
, drying, except carboxymethylcellulose calcium,
Water soluble starch,
Outside glucose, other raw materials are cut into block or sheet and are placed in desiccation in drying baker respectively, and temperature control exists
80-100
DEG C, the time
45
Minute, raw material moisture is evaporated to water content
18%
, compressing tablet；
C
, decoct, by above-mentioned ratio of weight and number, decocted during the raw material addition after drying is put into decocting device
2
It is secondary, add for the first time
7
Times water is decocted
1.5
Hour, second addition
5
Times water is decocted
1
Hour, filtrate is extracted in filtering respectively, will filtrate merging twice, the secondary filter dregs of a decoction and impurity, prepared extract solution；
D
, mixing, by above-mentioned ratio of weight and number, will be in extract solution by weight adding carboxymethylcellulose calcium, water soluble starch, glucose be sufficiently mixed uniformly, prepared mixed liquor；
E
, powder processed, the filtrate of above-mentioned mixed liquor is cooled to room temperature, filtrate is made mixed powder using spray drying process, it is standby；
F
, compressing tablet, by above-mentioned mixed powder remove production process in generation impurity, then using the mode and ultraviolet compressing tablet mode compressing tablet for radiating compressing tablet；Tablet press machine direct tablet compressing is utilized after compressing tablet；
G
, packaging, by the good tablet of above-mentioned pressing according to specification for sale pack.
With lozenge be combined the traditional Chinese medicine ingredients for having good tonic effect to human body by the present invention, there is more preferable assimilation effect compared to existing lozenge, it is convenient for people to usually take, conditioning health, increase metabolism balance in vivo, regulation human body homeostasis is softer, and lifting constitution is gentler, effective for a long time can increase human body power and work endurance.
Active ingredient in Chinese medicine is decocted and is made extract solution by the present invention, active ingredient is combined with lozenge, the nutriment in the Chinese medicine being effectively kept；By the proportioning of science, when product of the present invention is nourished human body, with mending without dry, trophic structure rationally, strengthens effect of human body constitution.
In inventive formulation, granatum relieving diarrhea with astringents, hemostasis, expelling parasite；For chronic diarrhea, protracted dysentery is had blood in stool, prolapse of the anus, uterine bleeding, leukorrhea, abdominal pain due to enterositosis；Smilax detoxifies, dehumidifying, sharp joint；Control syphilis, stranguria with turbid discharge, muscles and bones contraction pain, tinea pedis, furunculosis, carbuncle swells, scrofula；
Coptis purging intense heat, eliminating dampness, removing toxic substances, desinsection；Row heat toxin when controlling, typhoid fever, heat contains vexed, and feeling of fullness is vomitted inverse, bacillary dysentery, and heat rushes down stomachache, and lung knot is pressed, and tells, is defeated in battle, lower blood, quenches one's thirst, infantile malnutrition due to digestive disturbances or intestinalparasites, roundworm disease, pertussis, abscess of throat, pinkeye, aphtha, skin sore, eczema, the burning hot wound of soup；Rose promoting qi circulation and removing obstruction in the collateral, and blood, analgesic；For stomachache due to emotional depression and the hyperactive liver-qi attacking the stomach, deficiency of food evil of vomitting, irregular menstruation, the pain of injury caused by falling and tumbling；Sophora flower cooling blood and hemostasis, clearing liver-fire；For having blood in stool, hemorrhoid blood, bloody flux, uterine bleeding is spitted blood, bleeding from five sense organs or subcutaneous tissue, the hot hot eyes of liver, dizziness of having a headache；Caulis bambusae in taenian heat-clearing, cool blood, resolving sputum, antiemetic；Dysphoria with smothery sensation vomiting, hiccup are controlled, the hot cough and asthma of phlegm is spitted blood, and bleeding from five sense organs or subcutaneous tissue, uterine bleeding, vomiting during early pregnancy, a word used in place name is moved, frightened epilepsy；Acorn convergence is solid de-；Hemostasis；Removing toxic substances；Main dysentery；Have blood in stool；Hemorrhoid blood；Prolapse of the anus；Children's hernia；The long not mastitis of bursting of sore carbuncle；Orchitis；
Glossy privet leaf wind-dispelling, improving eyesight, detumescence, analgesic；Head's dusk pain is controlled, wind-heat is red with sore swells are festered, and are scalded, stomatitis
。
The present invention is summarized and perfect in taking and clinical verification by many cases patient, constantly, and recipe ratio is more complete, determined curative effect, and to chronic diarrhea, protracted dysentery is had blood in stool
Deng master
Disease
Card：Degree difference is served
Relieving diarrhea with astringents, hemostasis, expelling parasite
Effect,
Have
The advantages of health care, relieving diarrhea with astringents, pure natural, pollution-free, no side effectses.
The present invention through two groups of clinical verifications, for treatment group take lozenge of the present invention, take once a day by one of which, is within 7 days a course for the treatment of, and " relieving diarrhea with astringents dissipates " is taken in another group of control,
Take once a day, be within 7 days a course for the treatment of, every group selection outpatient 200, wherein man 100, female 100, measure the big age 72
It is year, minimum
Age 31
Year,
Clinical manifestation is chronic diarrhea, and protracted dysentery is had blood in stool, prolapse of the anus, uterine bleeding, abdominal pain due to enterositosis
,
Muscles and bones contraction pain, tinea pedis, furunculosis, carbuncle swells
, table one is to take the contrasting data after a course for the treatment of：
Table
1
Front and rear two groups of courses for the treatment of are taken to compare
(
Unit
:
People
)
There were significant differences for treatment group and control group, it will thus be seen that present invention application clinically has significant curative effect.
Technological advantage of the invention is：1st, raw material and scientific formulation are selected, production technology is advanced, its product produces taste well, convenient storage；2nd, without harmful components such as preservatives in product, nourishing and nutrition of the raw material to human body are kept, is easily absorbed by the body；3rd, raw material sources are extensive, plus process line is short, the manufacture of product easy processing.
Specific embodiment
With reference to specific embodiment, the present invention is further illustrated
Embodiment 1：Suitable for chronic diarrhea, protracted dysentery is had blood in stool
Crowd
Granatum relieving diarrhea with astringents lozenge of the present invention is prepared to be made up of following component raw material（Consumption is weight portion）,
Granatum
15-30
Part, smilax
10-20
Part, the coptis
5-15
Part, rose
3-15
Part, sophora flower
3-15
Part, caulis bambusae in taenian
3-10
Part, acorn
4-12
Part, glossy privet leaf
6-9
Part, carboxymethylcellulose calcium
7-10
Part, water soluble starch
4-8
Part, glucose
10-15
Part.
Embodiment 2：Suitable for prolapse of the anus, uterine bleeding, abdominal pain due to enterositosis
,
Muscles and bones contraction pain
Crowd
Preparing granatum relieving diarrhea with astringents lozenge preferred weight ratio range of the present invention is：
Granatum
15-25
Part, smilax
10-15
Part, the coptis
5-12
Part, rose
3-10
Part, sophora flower
3-10
Part, caulis bambusae in taenian
3-8
Part, acorn
4-10
Part, glossy privet leaf
6-8
Part, carboxymethylcellulose calcium
7-9
Part, water soluble starch
4-7
Part, glucose
10-14
Part.
Embodiment
3
：It is applied to
Tinea pedis, furunculosis, carbuncle swells
Crowd
Preparing granatum relieving diarrhea with astringents lozenge best weight ratio scope of the present invention is, 20 parts of granatum, 12 parts of smilax, 10 parts of the coptis, 8 parts of rose, 8 parts of sophora flower, 5 parts of caulis bambusae in taenian, 8 parts of acorn, 7 parts of glossy privet leaf, 8 parts of carboxymethylcellulose calcium, 6 parts of water soluble starch, 12 parts of glucose.
Embodiment 4
Above-mentioned each component is made the production method of granatum relieving diarrhea with astringents lozenge of the present invention, technical process is：
Sorting, drying, decoction, mixing, powder processed, compressing tablet, packaging, concrete operation method follow these steps to successively：
A
, sorting, by raw material weight proportioning of soup processed, select meet the granatum of national health and quality standard, smilax, the coptis, rose, sophora flower, caulis bambusae in taenian, acorn, glossy privet leaf, carboxymethylcellulose calcium,
Water soluble starch,
Glucose feed is standby；
B
, drying, except carboxymethylcellulose calcium,
Water soluble starch,
Outside glucose, other raw materials are cut into block or sheet and are placed in desiccation in drying baker respectively, and temperature control exists
80-100
DEG C, the time
45
Minute, raw material moisture is evaporated to water content
18%
, compressing tablet；
C
, decoct, by above-mentioned ratio of weight and number, decocted during the raw material addition after drying is put into decocting device
2
It is secondary, add for the first time
7
Times water is decocted
1.5
Hour, second addition
5
Times water is decocted
1
Hour, filtrate is extracted in filtering respectively, will filtrate merging twice, the secondary filter dregs of a decoction and impurity, prepared extract solution；
D
, mixing, by above-mentioned ratio of weight and number, will be in extract solution by weight adding carboxymethylcellulose calcium, water soluble starch, glucose be sufficiently mixed uniformly, prepared mixed liquor；
E
, powder processed, the filtrate of above-mentioned mixed liquor is cooled to room temperature, filtrate is made mixed powder using spray drying process, it is standby；
F
, compressing tablet, by above-mentioned mixed powder remove production process in generation impurity, then using the mode and ultraviolet compressing tablet mode compressing tablet for radiating compressing tablet；Tablet press machine direct tablet compressing is utilized after compressing tablet；
G
, packaging, by the good tablet of above-mentioned pressing according to specification for sale pack.
Claims (4)
1. a kind of granatum relieving diarrhea with astringents lozenge, it is characterised in that：It is that the raw material matched by following weight is made, granatum 15-30 parts, smilax 10-20 parts, coptis 5-15 parts, rose 3-15 parts, sophora flower 3-15 parts, caulis bambusae in taenian 3-10 parts, acorn 4-12 parts, glossy privet leaf 6-9 parts, carboxymethylcellulose calcium 7-10 parts, water soluble starch 4-8 parts, glucose 10-15 parts.
2. a kind of granatum relieving diarrhea with astringents lozenge according to claim 1, it is characterised in that：The weight proportion of wherein various raw materials is, granatum 15-25 parts, smilax 10-15 parts, coptis 5-12 parts, rose 3-10 parts, sophora flower 3-10 parts, caulis bambusae in taenian 3-8 parts, acorn 4-10 parts, glossy privet leaf 6-8 parts, carboxymethylcellulose calcium 7-9 parts, water soluble starch 4-7 parts, glucose 10-14 parts.
3. a kind of granatum relieving diarrhea with astringents lozenge according to claim 1, it is characterised in that：The weight proportion of wherein various raw materials is, 20 parts of granatum, 12 parts of smilax, 10 parts of the coptis, 8 parts of rose, 8 parts of sophora flower, 5 parts of caulis bambusae in taenian, 8 parts of acorn, 7 parts of glossy privet leaf, 8 parts of carboxymethylcellulose calcium, 6 parts of water soluble starch, 12 parts of glucose.
4. the production method of the granatum relieving diarrhea with astringents lozenge according to claim 1-3, it is characterised in that：Technical process is：Sorting, drying, decoction, mixing, powder processed, compressing tablet, packaging, concrete operation method follow these steps to successively：
A, sorting, by raw material weight proportioning of soup processed, select that to meet the granatum of national health and quality standard, smilax, the coptis, rose, sophora flower, caulis bambusae in taenian, acorn, glossy privet leaf, carboxymethylcellulose calcium, water soluble starch, glucose feed standby；
B, drying, in addition to carboxymethylcellulose calcium, water soluble starch, glucose, other raw materials are cut into block or sheet and are placed in desiccation in drying baker respectively, and temperature control 45 minutes time, makes raw material moisture be evaporated to water content 18%, compressing tablet at 80-100 DEG C；
C, decoction, by above-mentioned ratio of weight and number, decocted 2 times during the raw material addition after drying is put into decocting device, for the first time plus 7 times of waters are decocted 1.5 hours, add for second 5 times of waters to decoct 1 hour, filtrate is extracted in filtering respectively, filtrate will merge twice, the secondary filter dregs of a decoction and impurity, are obtained extract solution；
D, mixing, by above-mentioned ratio of weight and number, will be in extract solution by weight adding carboxymethylcellulose calcium, water soluble starch, glucose be sufficiently mixed uniformly, prepared mixed liquor；
E, powder processed, the filtrate of above-mentioned mixed liquor is cooled to room temperature, filtrate is made mixed powder using spray drying process, it is standby；
F, compressing tablet, the impurity that above-mentioned mixed powder is removed the generation in production process, then using the mode and ultraviolet compressing tablet mode compressing tablet for radiating compressing tablet；Tablet press machine direct tablet compressing is utilized after compressing tablet；
G, packaging, by the good tablet of above-mentioned pressing according to specification for sale pack.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510820469.4A CN106729196A (en) | 2015-11-24 | 2015-11-24 | A kind of granatum relieving diarrhea with astringents lozenge and its production method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510820469.4A CN106729196A (en) | 2015-11-24 | 2015-11-24 | A kind of granatum relieving diarrhea with astringents lozenge and its production method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106729196A true CN106729196A (en) | 2017-05-31 |
Family
ID=58963221
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510820469.4A Pending CN106729196A (en) | 2015-11-24 | 2015-11-24 | A kind of granatum relieving diarrhea with astringents lozenge and its production method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106729196A (en) |
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2015
- 2015-11-24 CN CN201510820469.4A patent/CN106729196A/en active Pending
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