CN106728134A - A kind of sweet wormwood heat-clearing lozenge and its production method - Google Patents
A kind of sweet wormwood heat-clearing lozenge and its production method Download PDFInfo
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- CN106728134A CN106728134A CN201510820394.XA CN201510820394A CN106728134A CN 106728134 A CN106728134 A CN 106728134A CN 201510820394 A CN201510820394 A CN 201510820394A CN 106728134 A CN106728134 A CN 106728134A
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- sweet wormwood
- heat
- compressing tablet
- glucose
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- 235000001405 Artemisia annua Nutrition 0.000 title claims abstract description 30
- 240000000011 Artemisia annua Species 0.000 title claims abstract description 30
- 239000007937 lozenge Substances 0.000 title claims abstract description 26
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 13
- 239000003826 tablet Substances 0.000 claims abstract description 32
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 26
- 239000002994 raw material Substances 0.000 claims abstract description 21
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 19
- 229920002472 Starch Polymers 0.000 claims abstract description 19
- 229940084030 carboxymethylcellulose calcium Drugs 0.000 claims abstract description 19
- 239000008103 glucose Substances 0.000 claims abstract description 19
- 239000008107 starch Substances 0.000 claims abstract description 19
- 235000019698 starch Nutrition 0.000 claims abstract description 19
- 241000143476 Bidens Species 0.000 claims abstract description 14
- 235000010662 Bidens pilosa Nutrition 0.000 claims abstract description 14
- 241000219764 Dolichos Species 0.000 claims abstract description 14
- 235000015826 Flagellaria indica Nutrition 0.000 claims abstract description 14
- 244000203167 Flagellaria indica Species 0.000 claims abstract description 14
- 241001632576 Hyacinthus Species 0.000 claims abstract description 14
- 235000012920 Oroxylum indicum Nutrition 0.000 claims abstract description 14
- 240000005790 Oroxylum indicum Species 0.000 claims abstract description 14
- 235000008291 Poterium sanguisorba Nutrition 0.000 claims abstract description 14
- 235000003202 Reynoutria sachalinensis Nutrition 0.000 claims abstract description 14
- 244000153955 Reynoutria sachalinensis Species 0.000 claims abstract description 14
- 235000008282 Sanguisorba officinalis Nutrition 0.000 claims abstract description 14
- 240000004064 Poterium sanguisorba Species 0.000 claims abstract description 13
- 238000001035 drying Methods 0.000 claims abstract description 13
- 230000036541 health Effects 0.000 claims abstract description 8
- 239000000843 powder Substances 0.000 claims abstract description 8
- 238000002156 mixing Methods 0.000 claims abstract description 7
- 238000004806 packaging method and process Methods 0.000 claims abstract description 7
- 239000000706 filtrate Substances 0.000 claims description 12
- 238000000034 method Methods 0.000 claims description 10
- 230000008569 process Effects 0.000 claims description 7
- 239000012535 impurity Substances 0.000 claims description 6
- 239000011812 mixed powder Substances 0.000 claims description 6
- 238000001914 filtration Methods 0.000 claims description 3
- -1 packaging Substances 0.000 claims description 3
- 238000003825 pressing Methods 0.000 claims description 3
- 235000014347 soups Nutrition 0.000 claims description 3
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- 239000003643 water by type Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 abstract description 7
- 230000000694 effects Effects 0.000 abstract description 7
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- 208000001848 dysentery Diseases 0.000 description 7
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- 208000011580 syndromic disease Diseases 0.000 description 4
- 206010003011 Appendicitis Diseases 0.000 description 3
- 206010018612 Gonorrhoea Diseases 0.000 description 3
- 206010037660 Pyrexia Diseases 0.000 description 3
- 241000700605 Viruses Species 0.000 description 3
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- 206010046788 Uterine haemorrhage Diseases 0.000 description 2
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- 230000001737 promoting effect Effects 0.000 description 2
- 208000024794 sputum Diseases 0.000 description 2
- 210000003802 sputum Anatomy 0.000 description 2
- 238000010025 steaming Methods 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
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- 238000012795 verification Methods 0.000 description 2
- 206010000077 Abdominal mass Diseases 0.000 description 1
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- 206010001928 Amenorrhoea Diseases 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- 206010022998 Irritability Diseases 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- 206010027514 Metrorrhagia Diseases 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 235000003143 Panax notoginseng Nutrition 0.000 description 1
- 241000180649 Panax notoginseng Species 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 244000173853 Sanguisorba officinalis Species 0.000 description 1
- 241000593989 Scardinius erythrophthalmus Species 0.000 description 1
- 241000270295 Serpentes Species 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 231100000540 amenorrhea Toxicity 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000009045 body homeostasis Effects 0.000 description 1
- 239000006189 buccal tablet Substances 0.000 description 1
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- 239000007891 compressed tablet Substances 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 239000007884 disintegrant Substances 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
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- 230000001605 fetal effect Effects 0.000 description 1
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- 235000013305 food Nutrition 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 208000003512 furunculosis Diseases 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A—HUMAN NECESSITIES
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/739—Sanguisorba (burnet)
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- A61K9/00—Medicinal preparations characterised by special physical form
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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Abstract
A kind of sweet wormwood heat-clearing lozenge and its production method.By sweet wormwood, beggar-ticks, yunnan supplejack root, flower of hyacinth dolichos, giant knotweed, radix scutellariae, garden burnet, Oroxylum indicum, carboxymethylcellulose calcium,
Water soluble starch,
Glucose
Constituted Deng raw material, finished product is made by sorting, drying, decoction, mixing, powder processed, compressing tablet, packaging.
Active ingredient in Chinese medicine is decocted and is made extract solution by the present invention, active ingredient is combined with lozenge, the nutriment in the Chinese medicine being effectively kept；By the proportioning of science, when product of the present invention is nourished human body, with mending without dry, trophic structure rationally, strengthens effect of human body constitution.The present invention
Have
Health care, heat-clearing, pure natural, pollution-free, no side effectses, the advantages of conveniently take and nourish the body.
Description
Technical field：
The present invention relates to field of food health care, and in particular to a kind of sweet wormwood heat-clearing lozenge and its production method.
Background technology
Buccal tablet refers to the compressed tablets for being contained in slow mechanism dissolved in oral cavity, and lozenge will have tempting color from inside to outside, so that the mouthfeel that user has had.Therefore, the figuration composition in lozenge, such as sugar, pigment additive often " a presumptuous guest usurps the role of the host " so that some by mistake lozenge is regarded as " sugar ".
At present, most of lozenge of in the market is all medicine, and most of medicines for being to treat Throat diseases, and narrow application range, therapeutic effect is general.And it is few using the utilization rate for being processed into health products containing chip technology, it is few to body-care effect, it is impossible to meet the market demand.
The content of the invention：
It is an object of the invention to provide one kind collection heat-clearing, it is pure natural, pollution-free,
No side effectses are conveniently taken and are nourished the body in one
Sweet wormwood heat-clearing lozenge and production method.
The object of the present invention is achieved like this.It is that the raw material matched somebody with somebody by following weight is made,
Sweet wormwood
15-30
Part, beggar-ticks
10-20
Part, yunnan supplejack root
5-15
Part, flower of hyacinth dolichos
3-15
Part, giant knotweed
3-15
Part, radix scutellariae
3-10
Part, garden burnet
4-12
Part, Oroxylum indicum
6-9
Part, carboxymethylcellulose calcium
7-10
Part, water soluble starch
4-8
Part, glucose
10-15
Part.
Preparing sweet wormwood heat-clearing lozenge preferred weight ratio range of the present invention is,
Sweet wormwood
15-25
Part, beggar-ticks
10-15
Part, yunnan supplejack root
5-12
Part, flower of hyacinth dolichos
3-10
Part, giant knotweed
3-10
Part, radix scutellariae
3-8
Part, garden burnet
4-10
Part, Oroxylum indicum
6-8
Part, carboxymethylcellulose calcium
7-9
Part, water soluble starch
4-7
Part, glucose
10-14
Part.
Preparing sweet wormwood heat-clearing lozenge best weight ratio scope of the present invention is,
Sweet wormwood
20
Part, beggar-ticks
12
Part, yunnan supplejack root
10
Part, flower of hyacinth dolichos
8
Part, giant knotweed
8
Part, radix scutellariae
5
Part, garden burnet
8
Part, Oroxylum indicum
7
Part, carboxymethylcellulose calcium
8
Part, water soluble starch
6
Part, glucose
12
Part.
Above-mentioned each component is made the production method of sweet wormwood heat-clearing lozenge of the present invention, technical process is：Sorting, drying, decoction, mixing, powder processed, compressing tablet, packaging, concrete operation method follow these steps to successively：
A
, sorting, by raw material weight proportioning of soup processed, select meet the sweet wormwood of national health and quality standard, beggar-ticks, yunnan supplejack root, flower of hyacinth dolichos, giant knotweed, radix scutellariae, garden burnet, Oroxylum indicum, carboxymethylcellulose calcium,
Water soluble starch,
Glucose feed is standby；
B
, drying, except carboxymethylcellulose calcium,
Water soluble starch,
Outside glucose, other raw materials are cut into block or sheet and are placed in desiccation in drying baker respectively, and temperature control exists
80-100
DEG C, the time
45
Minute, raw material moisture is evaporated to water content
18%
, compressing tablet；
C
, decoct, by above-mentioned ratio of weight and number, decocted during the raw material addition after drying is put into decocting device
2
It is secondary, add for the first time
7
Times water is decocted
1.5
Hour, second frame
5
Times water is decocted
1
Hour, filtrate is extracted in filtering respectively, will filtrate merging twice, the secondary filter dregs of a decoction and impurity, prepared extract solution；
D
, mixing, by above-mentioned ratio of weight and number, carboxymethylcellulose calcium, water soluble starch, glucose will be added to be sufficiently mixed uniformly in extract solution, prepared mixed liquor；
E
, powder processed, the filtrate of above-mentioned mixed liquor is cooled to room temperature, filtrate is made mixed powder using spray drying process, it is standby；
F
, compressing tablet, by above-mentioned mixed powder remove production process in generation impurity, then using the mode and ultraviolet compressing tablet mode compressing tablet for radiating compressing tablet；Tablet press machine direct tablet compressing is utilized after compressing tablet；
G
, packaging, by the good tablet of above-mentioned pressing according to specification for sale pack.
With lozenge be combined the traditional Chinese medicine ingredients for having good tonic effect to human body by the present invention, there is more preferable assimilation effect compared to existing lozenge, it is convenient for people to usually take, conditioning health, increase metabolism balance in vivo, regulation human body homeostasis is softer, and lifting constitution is gentler, effective for a long time can increase human body power and work endurance.
Active ingredient in Chinese medicine is decocted and is made extract solution by the present invention, active ingredient is combined with lozenge, the nutriment in the Chinese medicine being effectively kept；By the proportioning of science, when product of the present invention is nourished human body, with mending without dry, trophic structure rationally, strengthens effect of human body constitution.
In inventive formulation, sweet wormwood heat-clearing；Relieving summer-heat；Except steaming；Preventing malaria；Main hot summer weather；Summer-heat and damp；Damp-warm syndrome；Fever due to yin deficiency；Malaria；Jaundice；Beggar-ticks is clearing heat and detoxicating；Dispelling wind and eliminating dampness；Activating blood circulation and reducing swelling；Main abscess of throat；Diarrhea；Dysentery；Jaundice；Acute appendicitis；Furuncle swelling toxin；Snake is early bitten；Arthralgia pain due to rheumatism；Traumatic injury；
Yunnan supplejack root clearing heat and promoting diuresis；Promoting blood circulation and detoxication；Main heat gonorrhea；Jaundice；Dysentery；Under band；Uterine bleeding；Traumatic injury；Rheumatalgia pain；Carbuncle sore tumefacting virus；Control dysentery, jaundice, heat gonorrhea, metrorrhagia under band；Flower of hyacinth dolichos strengthening the spleen and stomach, dampness elimination of relieving summer heat；Control dysentery, diarrhea, leukorrhea with reddish discharge；Giant knotweed expelling wind and removing dampness, scattered stasis pain is relieving cough and reducing sputum；For joint pain, jaundice with damp-heat pathogen, Amenorrhea, abdominal mass, scald, injury from falling down, carbuncle sore tumefacting virus, coughing with a lot of sputum；Radix scutellariae rushes down excess fire, antiabortive except damp and hot, hemostasis；High fever polydipsia is controlled, cough with lung heat, damp-heat dysentery, jaundice, heat gonorrhea is told, is defeated in battle, collapses, is leaked, red eye, swell pain, fetal irritability, carbuncle swells furunculosis；Garden burnet cooling blood and hemostasis, removing toxic substances sore, for having blood in stool, hemorrhoid blood, bloody flux, uterine bleeding, scald, carbuncle sore tumefacting virus；
Oroxylum indicum removing heat from the lung and relieving sorethroat, soothing liver and harmonizing stomach, for cough with lung heat, larynx numbness, sound is mute, stomachache due to emotional depression and the hyperactive liver-qi attacking the stomach
。
The present invention is summarized and perfect in taking and clinical verification by many cases patient, constantly, and recipe ratio is more complete, determined curative effect, to hot summer weather, summer-heat and damp, damp-warm syndrome
Deng master
Disease
Card：Degree difference is served
Heat-clearing, relieving summer-heat, except steaming
Effect,
Have
The advantages of health care, heat-clearing, pure natural, pollution-free, no side effectses.
The present invention through two groups of clinical verifications, for treatment group take lozenge of the present invention, take once a day by one of which, and 7 days is a course for the treatment of, and " pure natural notoginseng flower " is taken in another group of control,
Take once a day, be within 7 days a course for the treatment of, every group selection outpatient 200, wherein man 100, female 100, measure the big age 84
It is year, minimum
Age 26
Year,
Clinical manifestation is hot summer weather, summer-heat and damp, damp-warm syndrome, fever due to yin deficiency, malaria, jaundice, abscess of throat, diarrhea, dysentery, acute appendicitis
, table one is to take the contrasting data after a course for the treatment of：
Table
1
Front and rear two groups of courses for the treatment of are taken to compare
(
Unit
:
People
)
There were significant differences for treatment group and control group, it will thus be seen that present invention application clinically has significant curative effect.
Technological advantage of the invention is：1st, raw material and scientific formulation are selected, production technology is advanced, its product produces taste well, convenient storage；2nd, without harmful components such as preservatives in product, nourishing and nutrition of the raw material to human body are kept, is easily absorbed by the body；3rd, raw material sources are extensive, plus process line is short, the manufacture of product easy processing.
Specific embodiment
With reference to specific embodiment, the present invention is further illustrated
Embodiment 1：Suitable for hot summer weather, summer-heat and damp, damp-warm syndrome
Crowd
Sweet wormwood heat-clearing lozenge of the present invention is prepared to be made up of following component raw material（Consumption is weight portion）,
Sweet wormwood
15-30
Part, beggar-ticks
10-20
Part, yunnan supplejack root
5-15
Part, flower of hyacinth dolichos
3-15
Part, giant knotweed
3-15
Part, radix scutellariae
3-10
Part, garden burnet
4-12
Part, Oroxylum indicum
6-9
Part, carboxymethylcellulose calcium
7-10
Part, water soluble starch
4-8
Part, glucose
10-15
Part.
Embodiment 2：Suitable for fever due to yin deficiency, malaria, jaundice, abscess of throat
Crowd
Preparing sweet wormwood heat-clearing lozenge preferred weight ratio range of the present invention is：
Sweet wormwood
15-25
Part, beggar-ticks
10-15
Part, yunnan supplejack root
5-12
Part, flower of hyacinth dolichos
3-10
Part, giant knotweed
3-10
Part, radix scutellariae
3-8
Part, garden burnet
4-10
Part, Oroxylum indicum
6-8
Part, carboxymethylcellulose calcium
7-9
Part, water soluble starch
4-7
Part, glucose
10-14
Part.
Embodiment
3
：It is applicable
Diarrhea, dysentery, acute appendicitis
Crowd
Preparing sweet wormwood heat-clearing lozenge best weight ratio scope of the present invention is, 20 parts of sweet wormwood, 12 parts of beggar-ticks, 10 parts of yunnan supplejack root, 8 parts of flower of hyacinth dolichos, 8 parts of giant knotweed, 5 parts of radix scutellariae, 8 parts of garden burnet, 7 parts of Oroxylum indicum, 8 parts of carboxymethylcellulose calcium, 6 parts of water soluble starch, 12 parts of glucose.
Embodiment 4
Above-mentioned each component is made the production method of sweet wormwood heat-clearing lozenge of the present invention, technical process is：Sorting, drying, decoction, mixing, powder processed, compressing tablet, packaging, concrete operation method follow these steps to successively：
A
, sorting, by raw material weight proportioning of soup processed, select meet the sweet wormwood of national health and quality standard, beggar-ticks, yunnan supplejack root, flower of hyacinth dolichos, giant knotweed, radix scutellariae, garden burnet, Oroxylum indicum, carboxymethylcellulose calcium,
Water soluble starch,
Glucose feed is standby；
B
, drying, except carboxymethylcellulose calcium,
Water soluble starch,
Outside glucose, other raw materials are cut into block or sheet and are placed in desiccation in drying baker respectively, and temperature control exists
80-100
DEG C, the time
45
Minute, raw material moisture is evaporated to water content
18%
, compressing tablet；
C
, decoct, by above-mentioned ratio of weight and number, decocted during the raw material addition after drying is put into decocting device
2
It is secondary, add for the first time
7
Times water is decocted
1.5
Hour, second frame
5
Times water is decocted
1
Hour, filtrate is extracted in filtering respectively, will filtrate merging twice, the secondary filter dregs of a decoction and impurity, prepared extract solution；
D
, mixing, by above-mentioned ratio of weight and number, carboxymethylcellulose calcium, water soluble starch, glucose will be added to be sufficiently mixed uniformly in extract solution, prepared mixed liquor；
E
, powder processed, the filtrate of above-mentioned mixed liquor is cooled to room temperature, filtrate is made mixed powder using spray drying process, it is standby；
F
, compressing tablet, by above-mentioned mixed powder remove production process in generation impurity, then using the mode and ultraviolet compressing tablet mode compressing tablet for radiating compressing tablet；Tablet press machine direct tablet compressing is utilized after compressing tablet；
G
, packaging, by the good tablet of above-mentioned pressing according to specification for sale pack.
Embodiment
2
If adding appropriate disintegrant such as in the prescription of lozenge
CMS-Na
Improve and contain tablet stability, or add the mediation mouthfeel such as cane sugar powder, mannitol, sorbierite, various sweeteners, essence.
Claims (4)
1. a kind of sweet wormwood heat-clearing lozenge, it is characterised in that：It is that the raw material matched by following weight is made, sweet wormwood 15-30 parts, beggar-ticks 10-20 parts, yunnan supplejack root 5-15 parts, flower of hyacinth dolichos 3-15 parts, giant knotweed 3-15 parts, radix scutellariae 3-10 parts, garden burnet 4-12 parts, Oroxylum indicum 6-9 parts, carboxymethylcellulose calcium 7-10 parts, water soluble starch 4-8 parts, glucose 10-15 parts.
2. a kind of sweet wormwood heat-clearing lozenge according to claim 1, it is characterised in that：The weight proportion of wherein various raw materials is, sweet wormwood 15-25 parts, beggar-ticks 10-15 parts, yunnan supplejack root 5-12 parts, flower of hyacinth dolichos 3-10 parts, giant knotweed 3-10 parts, radix scutellariae 3-8 parts, garden burnet 4-10 parts, Oroxylum indicum 6-8 parts, carboxymethylcellulose calcium 7-9 parts, water soluble starch 4-7 parts, glucose 10-14 parts.
3. a kind of sweet wormwood heat-clearing lozenge according to claim 1, it is characterised in that：The weight proportion of wherein various raw materials is, 20 parts of sweet wormwood, 12 parts of beggar-ticks, 10 parts of yunnan supplejack root, 8 parts of flower of hyacinth dolichos, 8 parts of giant knotweed, 5 parts of radix scutellariae, 8 parts of garden burnet, 7 parts of Oroxylum indicum, 8 parts of carboxymethylcellulose calcium, 6 parts of water soluble starch, 12 parts of glucose.
4. the production method of the sweet wormwood heat-clearing lozenge according to claim 1-3, it is characterised in that：Technical process is：Sorting, drying, decoction, mixing, powder processed, compressing tablet, packaging, concrete operation method follow these steps to successively：
A, sorting, by raw material weight proportioning of soup processed, select that to meet the sweet wormwood of national health and quality standard, beggar-ticks, yunnan supplejack root, flower of hyacinth dolichos, giant knotweed, radix scutellariae, garden burnet, Oroxylum indicum, carboxymethylcellulose calcium, water soluble starch, glucose feed standby；
B, drying, in addition to carboxymethylcellulose calcium, water soluble starch, glucose, other raw materials are cut into block or sheet and are placed in desiccation in drying baker respectively, and temperature control 45 minutes time, makes raw material moisture be evaporated to water content 18%, compressing tablet at 80-100 DEG C；
C, decoction, by above-mentioned ratio of weight and number, decocted 2 times during the raw material addition after drying is put into decocting device, for the first time plus 7 times of waters are decocted 1.5 hours, second frame, 5 times of waters are decocted 1 hour, and filtrate is extracted in filtering respectively, filtrate will be merged twice, the secondary filter dregs of a decoction and impurity, are obtained extract solution；
D, mixing, by above-mentioned ratio of weight and number, carboxymethylcellulose calcium, water soluble starch, glucose will be added to be sufficiently mixed uniformly in extract solution, prepared mixed liquor；
E, powder processed, the filtrate of above-mentioned mixed liquor is cooled to room temperature, filtrate is made mixed powder using spray drying process, it is standby；
F, compressing tablet, the impurity that above-mentioned mixed powder is removed the generation in production process, then using the mode and ultraviolet compressing tablet mode compressing tablet for radiating compressing tablet；Tablet press machine direct tablet compressing is utilized after compressing tablet；
G, packaging, by the good tablet of above-mentioned pressing according to specification for sale pack.
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|---|---|---|---|
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1579531A (en) * | 2004-05-17 | 2005-02-16 | 张红 | Medicinal composition for treating anemopyretic cold and its preparation method |
| CN104622946A (en) * | 2015-01-12 | 2015-05-20 | 福建农林大学 | Gynura bicolor heat-clearing buccal tablet and preparation method thereof |
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2015
- 2015-11-24 CN CN201510820394.XA patent/CN106728134A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1579531A (en) * | 2004-05-17 | 2005-02-16 | 张红 | Medicinal composition for treating anemopyretic cold and its preparation method |
| CN104622946A (en) * | 2015-01-12 | 2015-05-20 | 福建农林大学 | Gynura bicolor heat-clearing buccal tablet and preparation method thereof |
Non-Patent Citations (1)
| Title |
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| 杨家胜等: "自拟蒿芩银虎汤治疗感染性发热154例", 《黑龙江中医药》 * |
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