CN106728670A - A kind of goldfish loses the preventing and treating medicine of fish glue disease - Google Patents
A kind of goldfish loses the preventing and treating medicine of fish glue disease Download PDFInfo
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- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
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Abstract
The invention discloses the preventing and treating medicine that a kind of goldfish loses fish glue disease, the preventing and treating pack contains the following raw material：Vegetables and fruits ferment powder, Asiatic plantain, the coptis, the Radix Astragali, golden cypress, purslane, orange peel, the banksia rose, the dried immature fruit of citron orange, Fructus Aurantii, rhizoma nardostachyos, sword bean, the calyx and receptacle of a persimmon, dried orange peel, the fruit of Chinese magnoliavine, matrimony vine, glutinous rehmannia, Chinese yam, propolis, sulfamethoxazole, TMP.The present invention can be obviously improved goldfish to losing the immune disease-resistance ability of fish glue disease, fish glue disease is lost to goldfish has therapeutic action, the effects such as formula has aid digestion, anti-inflammatory, antibacterial, beneficial intestines, has significant results to the ability that the pancake circulation of vital energy in the wrong direction, the elimination stagnation of the circulation of vital energy, treatment enteritis, exclusion toxin, lifting liver fight toxins.The preventing and treating medicine that goldfish loses fish glue disease is combined the graininess that is made different-grain diameter with fish meal, the cure rate sick to goldfish mistake fish glue is up to more than 90%.
Description
Technical field
The invention belongs to technical field of Chinese medicine, the preventing and treating medicine of fish glue disease is lost more particularly, to a kind of goldfish.
Background technology
Today's society cultivation wind is prevailing, and ornamental fish and aquarium have been increasingly becoming the new fashion of new period household consumption.Gold
Fish is a kind of most commonly seen ornamental fish.In the common disease that goldfish is suffered from, it is considered as a kind of abnormally dangerous and difficulty to lose fish glue disease
With the goldfish disease cured.The mistake fish glue disease of goldfish is also called air bladder deficiency disorder, overturns disease, suffers from this sick goldfish and is unable to maintain that it
The balance of body, turns a somersault as having sometimes headlong, is not finally to sink to the bottom, exactly floats on the surface.Short body belly
Loose goldfish most often suffers from this disease, and sick fish also has dysregulated appetite, can survive a period of time, but lose ornamental value.For causing
The reason for mistake fish glue disease of goldfish, there is no final conclusion, and without effective method.General way is that stone is added in fish maw,
Or bolt foam helps goldfish to find balance with external force on dorsal fin, it is clear that this is the method cured the symptoms, not the disease.
The content of the invention
Fish glue medicine being lost for goldfish on Vehicles Collected from Market and developing not enough problem, fish glue disease is lost the invention provides a kind of goldfish
Preventing and treating medicine.
The present invention is realized by following technology：
A kind of goldfish loses the preventing and treating medicine of fish glue disease, and the preventing and treating pack contains the following raw material：Vegetables and fruits ferment powder, Asiatic plantain, the coptis, the Radix Astragali,
Golden cypress, purslane, orange peel, the banksia rose, the dried immature fruit of citron orange, Fructus Aurantii, rhizoma nardostachyos, sword bean, the calyx and receptacle of a persimmon, dried orange peel, the fruit of Chinese magnoliavine, matrimony vine, glutinous rehmannia, Chinese yam, honeybee
Glue, sulfamethoxazole, TMP.
Inventor studies discovery for many years, cause goldfish with air bladder detuning phenomena be bodily form reason, water level height and
The reasons such as feed.Fish glue is that goldfish grasps balance and the critical organ for drifting along, and fish glue lower section is the liver of detoxication and secrete digestive juicess,
Top is the kidney for discharging toxin, and fish glue, kidney, liver are nearly at centre position, and nephrotoxicity element fails effectively discharge, liver digestive juice secretion
It is not normal to cause oedema or air bladder ventilation not all to be freely to cause the main cause for losing fish glue disease.Inventor thinks that these factors are also mutual
Association, the liver of Xie Su effects, because water quality or food problems fail normally travel function, gradually injures with the kidney of discharge toxin
Internal organ formed organ oedema or atrophy, such as compromised liver function, can cause liver digestive juice cannot normal secretions, cause enteron aisle
Middle food cannot digest, and cause chronic enteritis, and lasting chronic enteritis will cause pneumatic duct to block, obstructed, the body of pneumatic duct
Product expansion, so as to cause the unbalance of goldfish, loses fish glue phenomenon and therefore occurs.
Inventor thinks that the treatment top priority for losing fish glue disease for goldfish is to strengthen the digestion of food, ventilation, gradually eliminates
Inflammation, protect liver and shield kidney are carried out again, each organ of goldfish is recovered normal.Sign in this, inventor selects vegetables and fruits ferment powder conduct
Promote the auxiliary reagent of goldfish food digestion, it may have the endocrine effect of balance；Selection has good ventilation, anti-inflammatory, shield kidney
The Chinese herbal medicine of effect loses the raw material of the preventing and treating medicine of fish glue disease as goldfish.Wherein, Asiatic plantain, the coptis, the Radix Astragali, golden cypress, purslane tool
There are heat-clearing, dampness elimination, anti-inflammatory, antibacterial, beneficial intestines effect, have special effect for treatment enteritis；Orange peel, the banksia rose, the dried immature fruit of citron orange, Fructus Aurantii,
Rhizoma nardostachyos, sword bean, the calyx and receptacle of a persimmon, dried orange peel have to be dredged smooth mechanism of qi, the pancake circulation of vital energy in the wrong direction, eliminates the stagnation of the circulation of vital energy, adjustment function；Matrimony vine, glutinous rehmannia, Chinese yam
Ability for excluding toxin, lifting liver fights toxins has significant results；Propolis is mild-natured, bitter, pungent, micro-sweet, there is anti-inflammatory
Effect of analgesic.In the present invention, in addition to medium-height grass explosive component, a small amount of sulfamethoxazole, TMP Western medicine be also added
Composition, both medicines have inhibitory action for most of Gram-positives and Gram-negative bacteria.It is mainly used in sensitive bacteria
Urinary tract infections, infection in respiratory system, enteric infection, infection of biliary tract and local soft tissue or trauma surface infestation for causing etc..
Preferably, the raw material weight proportioning of soup processed of the preventing and treating medicine is as follows：The weight portion of vegetables and fruits ferment powder 5~15, Asiatic plantain 10~
25 weight portions, the weight portion of the coptis 5~15, the weight portion of the Radix Astragali 5~10, the weight portion of golden cypress 5~10, the weight portion of purslane 5~10, tangerine
The weight portion of skin 3~5, the weight portion of the banksia rose 4~8, the weight portion of the dried immature fruit of citron orange 3~5, the weight portion of Fructus Aurantii 3~5, the weight portion of rhizoma nardostachyos 5~10, knife
The weight portion of beans 5~10, the weight portion of the calyx and receptacle of a persimmon 4~8, the weight portion of dried orange peel 4~8, the weight portion of propolis 3~5, the weight of sulfamethoxazole 1~2
Part, the weight portion of TMP 0.2~0.5.
Preferably, raw material of the vegetables and fruits ferment powder comprising following weight proportion：The weight portion of oranges and tangerines 5~10, strawberry 5~10
Weight portion, the weight portion of apple 5~10, the weight portion of banana 5~10, the weight portion of celery 10~15, the weight portion of hawthorn 10~20, radish
10~25 weight portions, the weight portion of lotus rhizome 10~20, the weight portion of crowndaisy chrysanthemum 10~25, the weight portion of tomato 10~20, white granulated sugar 10~
20 weight portions.
Preferably, the preparation process of the vegetables and fruits ferment powder is as follows：By oranges and tangerines, strawberry, apple, banana, celery, hawthorn,
Radish, lotus rhizome, crowndaisy chrysanthemum, tomato are cleaned, pasteurization, after chopping, insert in fermentation tank, add white granulated sugar, sealed fermenter
And ferment 5~7 months at ambient temperature, 200~300 filter and through vacuum freeze drying now, and vegetables and fruits ferment powder is obtained.
Preferably, the operation of pasteurization is as follows：It is heated to 68~70 DEG C, and keeps this temperature after 30~45 minutes, with
Cooling rate is rapidly cooled to 3~4 DEG C for 40~60 DEG C/minute.
Preferably, the temperature of vacuum freeze drying is -60~-40 DEG C, and vacuum is -0.08~-0.06MPa, and the time is
96~120 hours.
Preferably, the preparation process of the preventing and treating medicine of the goldfish mistake fish glue disease is as follows：
1）Weigh and mix Asiatic plantain, the coptis, the Radix Astragali, golden cypress, purslane, orange peel, the banksia rose, the dried immature fruit of citron orange, Fructus Aurantii, rhizoma nardostachyos, sword bean, persimmon
The base of a fruit, dried orange peel, it is cleaned, dry, be crushed to 50~100 mesh, herb powder is obtained, it is stand-by；
2）The edible ethanol aqueous solution of herb powder and mass percent 20%~50% is compared 1 with weight：20~30 mixing, in 50
After 30~45 minutes, 200~300 mesh are filtrated to get Chinese medicine extract to ultrasonication at~70 DEG C；
3）Chinese medicine extract is spray-dried, traditional Chinese medicine extraction powder is obtained final product；
4）Mixing vegetables and fruits ferment powder, traditional Chinese medicine extraction powder, propolis, sulfamethoxazole and TMP are simultaneously stirred, and obtain final product goldfish
Lose the preventing and treating medicine of fish glue disease.
Preferably, step 2）Described ultrasonic power is 300~400W, and frequency is 40KHz or 30KHz.
Preferably, step 3）Described spray drying is centrifugal spray drying, and its outlet temperature is 65~75 DEG C, entrance temperature
It is 280~320 DEG C to spend, and centrifugal atomizing nozzle rotating speed is 10000~15000 revs/min.
A kind of goldfish disclosed by the invention loses the preventing and treating medicine of fish glue disease, and its advantage is：Goldfish can be obviously improved to losing
The immune disease-resistance ability of fish glue disease, fish glue disease is lost to goldfish has therapeutic action, and the formula has aid digestion, anti-inflammatory, antibacterial, beneficial intestines etc.
Effect, for the pancake circulation of vital energy in the wrong direction, eliminate the stagnation of the circulation of vital energy, treatment enteritis, exclude toxin, the ability that fights toxins of lifting liver have substantially into
Effect.The preventing and treating medicine that goldfish loses fish glue disease is combined the graininess that is made different-grain diameter with fish meal, the healing sick to goldfish mistake fish glue
Rate can also increase the speed of growth of goldfish in addition up to more than 90%, improve the utilization rate of feed.
Specific embodiment
With reference to specific embodiment, the preventing and treating medicine of fish glue disease is lost to a kind of goldfish described in the present patent application.Should manage
Solution, specific embodiment described herein is only used to explain the present invention, is not intended to limit the present invention.
Embodiment 1
A kind of goldfish of the present invention loses the preventing and treating medicine of fish glue disease, and the raw material weight of the preventing and treating medicine is as follows：Vegetables and fruits ferment powder 5Kg, Asiatic plantain
10Kg, coptis 5Kg, Radix Astragali 5Kg, golden cypress 5Kg, purslane 5Kg, orange peel 3Kg, banksia rose 4Kg, dried immature fruit of citron orange 3Kg, Fructus Aurantii 3Kg, rhizoma nardostachyos
5Kg, sword bean 5Kg, calyx and receptacle of a persimmon 4Kg, dried orange peel 4Kg, propolis 3Kg, sulfamethoxazole 1Kg, TMP 0.2Kg.
In the formula of preventing and treating medicine that goldfish loses fish glue disease,
Raw material of the vegetables and fruits ferment powder comprising following weight：Oranges and tangerines 5Kg, strawberry 5Kg, apple 5Kg, banana 5Kg, celery 10Kg, mountain
Short, bristly hair or beard 10Kg, radish 10Kg, lotus rhizome 10Kg, crowndaisy chrysanthemum 10Kg, tomato 10Kg, white granulated sugar 10Kg, its preparation process are as follows：By oranges and tangerines,
Strawberry, apple, banana, celery, hawthorn, radish, lotus rhizome, crowndaisy chrysanthemum, tomato are cleaned, pasteurization, after chopping, insert fermentation
In tank, white granulated sugar is added, sealed fermenter and at ambient temperature fermentation 5 months, 200 filterings now are simultaneously dry through vacuum refrigeration
It is dry, using 200 mesh polyester material filter clothes, vegetables and fruits ferment powder is obtained.In the preparation process of vegetables and fruits ferment powder, the behaviour of pasteurization
Make as follows：Vegetables and fruits raw material is heated to 68 DEG C, and keeps this temperature after 30 minutes, rapidly cooled down with cooling rate as 40 DEG C/minute
To 3 DEG C；The temperature of vacuum freeze drying is -60 DEG C, and vacuum is -0.08MPa, and the time is 96 hours.
The preparation process that goldfish of the present invention loses the preventing and treating medicine of fish glue disease is as follows：
1）Weigh and mix Asiatic plantain, the coptis, the Radix Astragali, golden cypress, purslane, orange peel, the banksia rose, the dried immature fruit of citron orange, Fructus Aurantii, rhizoma nardostachyos, sword bean, persimmon
The base of a fruit, dried orange peel, it is cleaned, dry, be crushed to 50 mesh, herb powder is obtained, it is stand-by；
2）The edible ethanol aqueous solution of herb powder and mass percent 20% is compared 1 with weight：20 mixing, in ultrasound at 50 DEG C
After ripple is processed 30 minutes, 200 mesh are filtrated to get Chinese medicine extract, using 200 mesh polyester material filter clothes；
3）Chinese medicine extract is spray-dried, traditional Chinese medicine extraction powder is obtained final product；
4）Mixing vegetables and fruits ferment powder, traditional Chinese medicine extraction powder, propolis, sulfamethoxazole and TMP are simultaneously stirred, and obtain final product goldfish
Lose the preventing and treating medicine of fish glue disease.
In the preparation of preventing and treating medicine that goldfish loses fish glue disease, step 2）Ultrasonic power be 300W, frequency is 40KH；Step
3）Spray drying be centrifugal spray drying, its outlet temperature is 65 DEG C, and inlet temperature is 280 DEG C, and centrifugal atomizing nozzle rotating speed is
10000 revs/min.
Embodiment 2
A kind of goldfish of the present invention loses the preventing and treating medicine of fish glue disease, and the raw material weight of the preventing and treating medicine is as follows：Vegetables and fruits ferment powder 15Kg, Asiatic plantain
It is 25Kg, coptis 15Kg, Radix Astragali 10Kg, golden cypress 10Kg, purslane 10Kg, orange peel 5Kg, banksia rose 8Kg, dried immature fruit of citron orange 5Kg, Fructus Aurantii 5Kg, sweet
Loose 10Kg, sword bean 10Kg, calyx and receptacle of a persimmon 8Kg, dried orange peel 8Kg, propolis 5Kg, sulfamethoxazole 2Kg, TMP 0.5Kg.
In the formula of preventing and treating medicine that goldfish loses fish glue disease,
Raw material of the vegetables and fruits ferment powder comprising following weight：Oranges and tangerines 10Kg, strawberry 10Kg, apple 10Kg, banana 10Kg, celery
15Kg, hawthorn 20Kg, radish 25Kg, lotus rhizome 20Kg, crowndaisy chrysanthemum 25Kg, tomato 20Kg, white granulated sugar 20Kg, its preparation process are as follows：
After by oranges and tangerines, strawberry, apple, banana, celery, hawthorn, radish, lotus rhizome, crowndaisy chrysanthemum, cleaned tomato, pasteurization, chopping, put
Enter in fermentation tank, add white granulated sugar, sealed fermenter and at ambient temperature fermentation 7 months, 300 filterings now are simultaneously cold through vacuum
It is lyophilized dry, using 300 mesh nylon material filter clothes, vegetables and fruits ferment powder is obtained.In the preparation process of vegetables and fruits ferment powder, pasteurization
Operation it is as follows：Vegetables and fruits raw material is heated to 70 DEG C, and keeps this temperature after 45 minutes, with cooling rate as 60 DEG C/minute rapidly
It is cooled to 4 DEG C；The temperature of vacuum freeze drying is -40 DEG C, and vacuum is -0.06MPa, and the time is 120 hours.
The preparation process that goldfish of the present invention loses the preventing and treating medicine of fish glue disease is as follows：
1）Weigh and mix Asiatic plantain, the coptis, the Radix Astragali, golden cypress, purslane, orange peel, the banksia rose, the dried immature fruit of citron orange, Fructus Aurantii, rhizoma nardostachyos, sword bean, persimmon
The base of a fruit, dried orange peel, it is cleaned, dry, be crushed to 100 mesh, herb powder is obtained, it is stand-by；
2）The edible ethanol aqueous solution of herb powder and mass percent 50% is compared 1 with weight：30 mixing, in ultrasound at 70 DEG C
After ripple is processed 45 minutes, 300 mesh are filtrated to get Chinese medicine extract, using 300 mesh nylon material filter clothes；
3）Chinese medicine extract is spray-dried, traditional Chinese medicine extraction powder is obtained final product；
4）Mixing vegetables and fruits ferment powder, traditional Chinese medicine extraction powder, propolis, sulfamethoxazole and TMP are simultaneously stirred, and obtain final product goldfish
Lose the preventing and treating medicine of fish glue disease.
In the preparation of preventing and treating medicine that goldfish loses fish glue disease, step 2）Ultrasonic power be 400W, frequency is 30KH；Step
3）Spray drying be centrifugal spray drying, its outlet temperature is 75 DEG C, and inlet temperature is 320 DEG C, and centrifugal atomizing nozzle rotating speed is
15000 revs/min.
Embodiment 3
A kind of goldfish of the present invention loses the preventing and treating medicine of fish glue disease, and the raw material weight of the preventing and treating medicine is as follows：Vegetables and fruits ferment powder 10Kg, Asiatic plantain
15Kg, coptis 10Kg, Radix Astragali 8Kg, golden cypress 8Kg, purslane 8Kg, orange peel 4Kg, banksia rose 6Kg, dried immature fruit of citron orange 4Kg, Fructus Aurantii 4Kg, rhizoma nardostachyos
8Kg, sword bean 7Kg, calyx and receptacle of a persimmon 6Kg, dried orange peel 6Kg, propolis 4Kg, sulfamethoxazole 1.5Kg, TMP 0.4Kg.
In the formula of preventing and treating medicine that goldfish loses fish glue disease,
Raw material of the vegetables and fruits ferment powder comprising following weight：Oranges and tangerines 8Kg, strawberry 8Kg, apple 7Kg, banana 7Kg, celery 12Kg, mountain
Short, bristly hair or beard 15Kg, radish 15Kg, lotus rhizome 15Kg, crowndaisy chrysanthemum 15Kg, tomato 15Kg, white granulated sugar 15Kg, its preparation process are as follows：By oranges and tangerines,
Strawberry, apple, banana, celery, hawthorn, radish, lotus rhizome, crowndaisy chrysanthemum, tomato are cleaned, pasteurization, after chopping, insert fermentation
In tank, white granulated sugar is added, sealed fermenter and at ambient temperature fermentation 6 months, 250 filterings now are simultaneously dry through vacuum refrigeration
It is dry, using 250 mesh nylon material filter clothes, vegetables and fruits ferment powder is obtained.In the preparation process of vegetables and fruits ferment powder, the behaviour of pasteurization
Make as follows：Vegetables and fruits raw material is heated to 69 DEG C, and keeps this temperature after 40 minutes, rapidly cooled down with cooling rate as 50 DEG C/minute
To 4 DEG C；The temperature of vacuum freeze drying is -50 DEG C, and vacuum is -0.07MPa, and the time is 108 hours.
The preparation process that goldfish of the present invention loses the preventing and treating medicine of fish glue disease is as follows：
1）Weigh and mix Asiatic plantain, the coptis, the Radix Astragali, golden cypress, purslane, orange peel, the banksia rose, the dried immature fruit of citron orange, Fructus Aurantii, rhizoma nardostachyos, sword bean, persimmon
The base of a fruit, dried orange peel, it is cleaned, dry, be crushed to 80 mesh, herb powder is obtained, it is stand-by；
2）The edible ethanol aqueous solution of herb powder and mass percent 35% is compared 1 with weight：25 mixing, in ultrasound at 60 DEG C
After ripple is processed 40 minutes, 250 mesh are filtrated to get Chinese medicine extract, using 300 mesh nylon material filter clothes；
3）Chinese medicine extract is spray-dried, traditional Chinese medicine extraction powder is obtained final product；
4）Mixing vegetables and fruits ferment powder, traditional Chinese medicine extraction powder, propolis, sulfamethoxazole and TMP are simultaneously stirred, and obtain final product goldfish
Lose the preventing and treating medicine of fish glue disease.
In the preparation of preventing and treating medicine that goldfish loses fish glue disease, step 2）Ultrasonic power be 350W, frequency is 40KH；Step
3）Spray drying be centrifugal spray drying, its outlet temperature is 70 DEG C, and inlet temperature is 300 DEG C, and centrifugal atomizing nozzle rotating speed is
12000 revs/min.
In order to further verify that made medicine of the invention loses the therapeutic effect of fish glue disease to goldfish, refer to and reality is implemented as follows
Example：
Choose 100 and suffer from the goldfish for losing fish glue disease, be randomly divided into control group and experimental group, every group 50.1Kg is taken by of the invention real
The preventing and treating medicine for applying the mistake fish glue disease of the goldfish obtained by example 3 is well mixed with 10Kg fish meals, for feeding experimental group.To be not added with goldfish
The fish meal for losing fish glue disease preventing and treating medicine is fed to control group.The goldfish survival condition of observation seven days is as shown in table 1.
Table 1 suffers from the goldfish survival bar number of two weeks for losing fish glue disease
| Group | 1st day | 2nd day | 3rd day | 4th day | 5th day | 6th day | 7th day |
| Control group | 50 | 45 | 35 | 33 | 25 | 10 | 8 |
| Experimental group | 50 | 49 | 47 | 46 | 46 | 45 | 45 |
| Group | 8th day | 9th day | 10th day | 11st day | 12nd day | 13rd day | 14th day |
| Control group | 8 | 4 | 3 | 3 | 3 | 2 | 2 |
| Experimental group | 45 | 45 | 45 | 45 | 45 | 45 | 45 |
As can be seen from Table 1, in control group, it is 30% to suffer within the 3rd day and lose the sick goldfish death rate of fish glue, and 84% goldfish can be in one week
Death, 96% goldfish survival period, it follows that it is a kind of pernicious fish disease of comparing to lose fish glue disease, was not treated less than 14 days
Survival period is very short.In the experimental group for losing fish glue disease using the goldfish obtained by the embodiment of the present invention 3, gold is just controlled within the 3rd day
Fish loses fish glue disease, and the death rate is only 6%, a small number of（2）Goldfish starts to recover belly down, the 7th day overwhelming majority（40）Goldfish is extensive
Multiple normal, all of goldfish recovers normal within the 9th day, and two weeks survival rates of experimental group goldfish of statistics are 90%.Can by data above
Know, the goldfish obtained by the present invention loses the sick preventing and treating medicine of fish glue to the mistake fish glue disease of goldfish and has significant curative effect.
Claims (9)
1. a kind of goldfish loses the preventing and treating medicine of fish glue disease, it is characterised in that the preventing and treating pack contains the following raw material：Vegetables and fruits ferment powder, Chinese herbaceous peony
Grass, the coptis, the Radix Astragali, golden cypress, purslane, orange peel, the banksia rose, the dried immature fruit of citron orange, Fructus Aurantii, rhizoma nardostachyos, sword bean, the calyx and receptacle of a persimmon, dried orange peel, the fruit of Chinese magnoliavine, matrimony vine,
Glutinous rehmannia, Chinese yam, propolis, sulfamethoxazole, TMP.
2. a kind of goldfish according to claim 1 loses the preventing and treating medicine of fish glue disease, it is characterised in that the raw material weight of the preventing and treating medicine
Amount proportioning is as follows：The weight portion of vegetables and fruits ferment powder 5~15, the weight portion of Asiatic plantain 10~25, the weight portion of the coptis 5~15, the Radix Astragali 5~10
Weight portion, the weight portion of golden cypress 5~10, the weight portion of purslane 5~10, the weight portion of orange peel 3~5, the weight portion of the banksia rose 4~8, the dried immature fruit of citron orange 3
~5 weight portions, the weight portion of Fructus Aurantii 3~5, the weight portion of rhizoma nardostachyos 5~10, the weight portion of sword bean 5~10, the weight portion of the calyx and receptacle of a persimmon 4~8, dried orange peel 4
~8 weight portions, the weight portion of propolis 3~5, the weight portion of sulfamethoxazole 1~2, the weight portion of TMP 0.2~0.5.
3. a kind of goldfish according to claim 1 and 2 loses the preventing and treating medicine of fish glue disease, it is characterised in that the vegetables and fruits ferment powder
Raw material comprising following weight proportion：The weight portion of oranges and tangerines 5~10, the weight portion of strawberry 5~10, the weight portion of apple 5~10, banana 5
~10 weight portions, the weight portion of celery 10~15, the weight portion of hawthorn 10~20, the weight portion of radish 10~25, the weight of lotus rhizome 10~20
Part, the weight portion of crowndaisy chrysanthemum 10~25, the weight portion of tomato 10~20, the weight portion of white granulated sugar 10~20.
4. a kind of goldfish according to claim 3 loses the preventing and treating medicine of fish glue disease, it is characterised in that the system of the vegetables and fruits ferment powder
Standby step is as follows：By oranges and tangerines, strawberry, apple, banana, celery, hawthorn, radish, lotus rhizome, crowndaisy chrysanthemum, tomato be cleaned, Pasteur is gone out
After bacterium, chopping, insert in fermentation tank, addition white granulated sugar, sealed fermenter and at ambient temperature fermentation 5~7 months, 200~
300 filter and through vacuum freeze drying now, and vegetables and fruits ferment powder is obtained.
5. a kind of goldfish according to claim 4 loses the preventing and treating medicine of fish glue disease, it is characterised in that the operation of pasteurization is such as
Under：68~70 DEG C are heated to, and keep this temperature after 30~45 minutes, 3 are rapidly cooled to cooling rate as 40~60 DEG C/minute
~4 DEG C.
6. a kind of goldfish according to claim 4 loses the preventing and treating medicine of fish glue disease, it is characterised in that the temperature of vacuum freeze drying
It it is -60~-40 DEG C, vacuum is -0.08~-0.06MPa, the time is 96~120 hours.
7. a kind of goldfish according to claim 1 loses the preventing and treating medicine of fish glue disease, it is characterised in that the goldfish loses the anti-of fish glue disease
The preparation process for controlling medicine is as follows：
1）Weigh and mix Asiatic plantain, the coptis, the Radix Astragali, golden cypress, purslane, orange peel, the banksia rose, the dried immature fruit of citron orange, Fructus Aurantii, rhizoma nardostachyos, sword bean, persimmon
The base of a fruit, dried orange peel, it is cleaned, dry, be crushed to 50~100 mesh, herb powder is obtained, it is stand-by；
2）The edible ethanol aqueous solution of herb powder and mass percent 20%~50% is compared 1 with weight：20~30 mixing, in 50
After 30~45 minutes, 200~300 mesh are filtrated to get Chinese medicine extract to ultrasonication at~70 DEG C；
3）Chinese medicine extract is spray-dried, traditional Chinese medicine extraction powder is obtained final product；
4）Mixing vegetables and fruits ferment powder, traditional Chinese medicine extraction powder, propolis, sulfamethoxazole and TMP are simultaneously stirred, and obtain final product goldfish
Lose the preventing and treating medicine of fish glue disease.
8. a kind of goldfish according to claim 7 loses the preventing and treating medicine of fish glue disease, it is characterised in that step 2）Described ultrasonic wave
Power is 300~400W, and frequency is 40KHz or 30KHz.
9. a kind of goldfish according to claim 7 loses the preventing and treating medicine of fish glue disease, it is characterised in that step 3）Described spraying is done
Dry is centrifugal spray drying, and its outlet temperature is 65~75 DEG C, and inlet temperature is 280~320 DEG C, and centrifugal atomizing nozzle rotating speed is
10000~15000 revs/min.
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