CN106727057A - Children's bacteriostatic hand sanitizer and its production method - Google Patents
Children's bacteriostatic hand sanitizer and its production method Download PDFInfo
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- CN106727057A CN106727057A CN201710125270.9A CN201710125270A CN106727057A CN 106727057 A CN106727057 A CN 106727057A CN 201710125270 A CN201710125270 A CN 201710125270A CN 106727057 A CN106727057 A CN 106727057A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/604—Alkylpolyglycosides; Derivatives thereof, e.g. esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
Abstract
The present invention relates to a kind of children's bacteriostatic hand sanitizer and its production method, it is characterized in that, composition including following parts by weight, wherein, 5 15 parts of APG, 13 parts of glycerine, 0.01 0.1 parts of natural essence, 0.1 2.0 parts of sodium chloride, 15 parts of NMF, 15 parts of chelating agent, 0.1 1 parts of plant antimicrobial, 10 30 parts of deionized water.Children's bacteriostatic hand sanitizer of the present invention is safe and non-stimulating, fungistatic effect substantially, can go rapidly to eliminate the unusual smell, effectively remove all kinds of oil stains, spot, it is non-stimulated to child skin；NMF in hand cleanser contributes to the moisturizing of child skin, while both hands are cleaned, can moisten, moisturizing children's hand skin.
Description
Technical field
The invention belongs to household chemicals detergent applications, more particularly to a kind of bacteriostatic hand sanitizer suitable for children and
Its production method.
Background technology
With the progress and the improvement of people's living standards of society, conventional hand-washing article from the single soap stage by
Gradually develop into soap, perfumed soap and hand cleanser coexistence phase.Soap has good clean effect, and perfumed soap not only has preferably
Clean effect, while the happy people of fragrant odour.But both products are easily slid when using, hot mastication and contamination hand dirt,
Easy cross-infection after bacterium.Based on this, hand cleanser arises at the historic moment.The main function of hand cleanser is to play the work of cleaning skin care
With some specific compositions can play sterilization, sterilized effect, such as Escherichia coli etc., but fake products has been washed on the contrary
It is larger to hand skin injury.One class is common hand cleanser, a generic sterile products, and a special class belongs to heavy oil dirt and washes one's hands in addition
Liquid.The former plays a part of to clean decontamination, and the latter just contains antibacterial, antibacterial or sterilized active ingredient.Heavy oil dirt hand cleanser is then
It is used for industrial class greasy dirt（Such as machine oil, gasoline, butter, diesel oil etc.）With the cleaning of stain.Different hand cleanser are in outsourcing
Difference is loaded onto, common hand cleanser is generally " quasi-font size ", disinfection hand cleanser is generally " disappear font size ".Hand cleanser it is general it is without phosphorus,
The compositions such as aluminium, alkali, sodium alkyl benzene sulfonate, using the principle of gentle decontamination, are easily received by skin.
In addition, hand wash for children on the market is mainly broad spectrum activity disinfection hand wash for children now, generally in youngster
Addition and the preferable broad-spectrum germicide of hand wash for children component compatibility in virgin hand cleanser, such as 2,4,4-three chloro- 2-
The bactericide such as hydroxyl phenylate, xylene chloride phenol and triclosan, such irritant smell of disinfectant, are irritating to the skin, and have
Corrosivity, stability is poor, and the bactericidal action duration is short.Children's bears a pretty, delicate skin, to environmental factors such as drying, cold, humidities
And the chemical stimulation such as alkalescence, acidity is sensitive, resistivity is weaker.
Therefore, be badly in need of a kind of safe and non-stimulating, fungistatic effect of exploitation substantially, can go rapidly to eliminate the unusual smell, effectively remove each
Class oil stain, spot, it is adaptable to the hand cleanser of children.
The content of the invention
It is an object of the invention to provide the safe and non-stimulating, fungistatic effect of one kind substantially, can go rapidly to eliminate the unusual smell, it is effectively clear
It is non-stimulated to skin except all kinds of oil stains, spot, it is adaptable to the bacteriostatic hand sanitizer and its production method of children, the hand wash for children
Effectively by the dirt removal of skin surface, and can suppress the growth of various bacteriums, the NMF in hand cleanser is helped
In the moisturizing of child skin, while both hands are cleaned, can moisten, moisturizing children's hand skin.
What the present invention was realized in：
A kind of bacteriostatic hand sanitizer, it is characterised in that the composition including following parts by weight, wherein, APG 5-15 parts, glycerine
1-3 parts, natural essence 0.01-0.1 parts, sodium chloride 0.1-2.0 parts, NMF 1-5 parts, chelating agent 1-5 parts, plant antimicrobial
0.1-1 parts, deionized water 10-30 parts.
Further preferably, the natural essence is compounded by winter jasmine flower extract, violet extract and Diranthus chinensis extract
Combine, winter jasmine flower extract, violet extract, the weight ratio of Diranthus chinensis extract are 1-2:1:1.
Further preferably, the extracting method of the natural essence is that winter jasmine, violet or pink are spread out in into bamboo sieve
On, bamboo screening layered is put on the shelf of the fragrant case of closed collection, allow winter jasmine, violet or pink to tell perfume (or spice) naturally, and with drawing
Blower fan is delivered to the fragrance and moisture of winter jasmine, violet or pink in the fragrant case of collection in ice maker condensate pans, and fragrance and moisture converge
Gather and flow into cold dish after liquid essential oil is liquefied as in condenser pipe, the liquid essential oil in cold dish is finally collected into sealing not in time
In rust steel cylinder, extraction time is 10-30 minutes, and telling fragrance until winter jasmine, violet or pink completes.
Winter jasmine, alias：Small chrysanthemum, drooping stringbush flower root and bark, yellow plum, clear and bright flower,【Latin literary fame】Jasminum nudiflorum.
It is Oleaceae jasmine.Winter jasmine is containing secoiridoid, flavone compound, winter jasmine anthoxanthin, volatilization
The various biological active component such as oils and fatty acid and polysaccharide, with anti-oxidant, antibacterial and anti-inflammation functions.
Violet,【Alias】Careless sweet osmanthus, four peaches gram, careless violet,【Latin name】Matthiola incana (L.) R. Br. Cruciferae herbaceous plant；Violet essential have antibacterial, cough-relieving, diuresis, emetic, resolving sputum, hypocatharsis, control chest disease,
Calm effect.Violet essential contributes to hypersensitive cough and pertussis, is particularly suited for the problem in terms of breathing, can help
Help and fall asleep, have abirritation to antimigraine, it is adaptable to all skins, prevent dry skin, Bergamot Mint Extract is beneficial to wound
Mouth, the become silted up blue or green, skin of obstruction, swelling and inflammation, moreover it is possible to improve cracked skin.
Pink,【Alias】Chinese China pink, Luoyang China pink, Shi Ju, embroidery bamboo, carnation,【Latin name】Dianthus chinensis.It is the herbaceos perennial of Caryophyllaceae, Carnation；Pink herb contains saponin(e, volatile oil, in oil predominantly
Eugenol, benzyl carbinol, Ergol, benzyl salicylate, gaultherolin.Lead to sterilized antibacterial, reducing fever and causing diuresis, blood-breaking
Blood, the effect of promoting blood circulation and removing blood stasis.
Further preferably, the NMF is by olive oil, rice bran oil and galam butter 1-3 by volume:1:0.5 composition.
Further preferably, the chelating agent is ethylenediamine tetra-acetic acid, disodium ethylene diamine tetraacetate, sodium ethylene diamine tetracetate
One or more in salt, ethylenediamine tetrapropionic acid, ethylenediamine tetrapropionic acid sodium salt, sodium gluconate or sodium citrate.
Further preferably, the plant antimicrobial is by bergamot berry extract, Herba Patriniae extract and atractylodes japonica extract
Compounded combination is formed, and bergamot berry extract, Herba Patriniae extract, the weight ratio of atractylodes japonica extract are 1-2:1:1.
Further preferably, the extracting method of the plant antimicrobial is to be broken into bergamot fruit, field pennycress or atractylodes japonica
Powdery, is extracted 2-3 hours with the 5-10 times of alcohol reflux measured, continuous to extract three times, is then concentrated in vacuo extract solution, is obtained final product.
Bergamot really,【Alias】Balm, oswegotea, Indian feather,【Latin name】bergamot.Bergamot
Fruit contains bergamio, linalool, terpinol, nerol, dihydro pillapiol, citral, bergaptol, ortho-aminobenzoic acid
The compositions such as methyl esters.With multiple efficacies such as sterilization, anti-inflammation, enhancing body immunities.
Field pennycress,【Alias】HERBA THALASPIS, penny cress,【Latin name】Thlaspi arvense Linn.Field pennycress contains spends in vain
Patrinoside（villoside）, morroniside（morroniside）, loganin（loganin）Deng composition, with disease-resistant original
Microorganism, there is stronger inhibitory action, and the calm effect with hepatic cholagogic to staphylococcus aureus.
Atractylodes japonica,【Alias】Red art, Ma Ji, blue or green art, magic arts,【Latin name】Atractylodes japonica.It is chrysanthemum
Section herbaceos perennial.Atractylodes japonica is containing the compositions such as cupreol, atractylenolid Ⅲ, Daucosterol, vanillic acid, volatile oil, tool
There is antibacterial disinfective action, it has obvious suppression to staphylococcus aureus, hemolytic streptococcus, comma bacillus, shigella dysenteriae etc.
Make and use.
The production method of children's bacteriostatic hand sanitizer of the invention, comprises the following steps：
Appropriate deionized water is added in retort, APG, glycerine, NMF, chelating agent is subsequently adding, fully stirred
Mix to being completely dissolved, with newborn acid for adjusting pH to 7.0-7.2, add natural essence, plant antimicrobial, adjusted finally by sodium chloride
Viscosity needed for, it is filling after stirring.The prominent substantive distinguishing features of the present invention and significant progress are：
The prominent substantive distinguishing features of the present invention and significant progress are：
1st, children's bacteriostatic hand sanitizer of the present invention is safe and non-stimulating, fungistatic effect substantially, can go rapidly to eliminate the unusual smell, effectively remove each
Class oil stain, spot, it is non-stimulated to child skin；NMF in hand cleanser contributes to the moisturizing of child skin, in cleaning both hands
While, can moisten, moisturizing children's hand skin.
2nd, antiseptic of the invention is formed using the extract compounded combination of bergamot fruit, field pennycress and atractylodes japonica, is passed through
Long-term experiment, compare repeatedly and use, drawn scientific compatibility, with good bactericidal and bacteriostatic effect, particularly suppressing
Staphylococcus aureus, Escherichia coli and streptococcus aspect have synergy, and bactericidal reaches more than 90%；And antibacterial
Agent complicated component, its action site（Target spot）It is many, multiple physiological systems of bacterium are can act on, be conducive to overcoming the anti-of bacterium
The property of medicine；In addition, antiseptic of the present invention will not change the stabilising system of former hand cleanser substantially, the hand cleanser that production is obtained has good
Stability, undergone no deterioration within the shelf-life.
3rd, natural essence is formed by winter jasmine flower extract, violet extract and Diranthus chinensis extract compounded combination, not only
The peat-reek that can obtain skin, also with antibacterial, anti-corrosion, mildew-proof function.
Specific embodiment
The present invention is made the following instructions with reference to embodiment.
Embodiment 1
Raw material（Count by weight）：
5 parts of APG, 1 part of glycerine, 0.01 part of natural essence, 0.1 part of sodium chloride, 1 part of NMF, 1 part of chelating agent（Ethylenediamine
Tetraacethyl）, 0.1 part of plant antimicrobial, 10 parts of deionized water.
Production method：
Appropriate deionized water is added in retort, APG, glycerine, NMF, chelating agent is subsequently adding, fully stirred
Mix to being completely dissolved, with newborn acid for adjusting pH to 7.0-7.2, add natural essence, plant antimicrobial, adjusted finally by sodium chloride
Viscosity needed for, it is filling after stirring.
Embodiment 2
Raw material（Count by weight）：
8 parts of APG, 2 parts of glycerine, 0.05 part of natural essence, 0.5 part of sodium chloride, 2 parts of NMF, 2 parts of chelating agent（Glucose
Sour sodium）, 0.5 part of plant antimicrobial, 20 parts of deionized water.
The production method of above bacteriostatic hand sanitizer is with embodiment 1.
Embodiment 3
Raw material（Count by weight）：
12 parts of APG, 2.5 parts of glycerine, 0.08 part of natural essence, 1 part of sodium chloride, 3 parts of NMF, 3 parts of chelating agent（Second two
Amine tetraacethyl, disodium ethylene diamine tetraacetate and disodium edta）, 0.7 part of plant antimicrobial, 25 parts of deionized water.
The production method of above bacteriostatic hand sanitizer is with embodiment 1.
Embodiment 4
Raw material（Count by weight）：
15 parts of APG, 3 parts of glycerine, 0.1 part of natural essence, 2.0 parts of sodium chloride, 5 parts of NMF, 5 parts of chelating agent（Glucose
Sour sodium and sodium citrate）, 1 part of plant antimicrobial, 30 parts of deionized water.
The production method of above bacteriostatic hand sanitizer is with embodiment 1.
Claims (8)
1. a kind of children's bacteriostatic hand sanitizer, it is characterised in that the composition including following parts by weight, wherein, APG 5-15
Part, glycerine 1-3 parts, natural essence 0.01-0.1 parts, sodium chloride 0.1-2.0 parts, NMF 1-5 parts, chelating agent 1-5 parts, plant
Antiseptic 0.1-1 parts, deionized water 10-30 parts.
2. children's bacteriostatic hand sanitizer according to claim 1, it is characterised in that：The natural essence is extracted by winter jasmine
Thing, violet extract and Diranthus chinensis extract compounded combination are formed, and winter jasmine flower extract, violet extract, pink are carried
The weight ratio for taking thing is 1-2:1:1.
3. children's bacteriostatic hand sanitizer according to claim 2, it is characterised in that：The extracting method of the natural essence be by
Winter jasmine, violet or pink are spread out on bamboo sieve, and bamboo screening layered is put on the shelf of the fragrant case of closed collection, allow winter jasmine
Flower, violet or pink tell perfume (or spice) naturally, and with air-introduced machine the fragrance and water for collecting winter jasmine, violet or pink in fragrant case
To in ice maker condensate pans, fragrance and moisture being converged in after be liquefied as liquid essential oil in condenser pipe and flowing into cold dish, finally will be cold for dispensing
Liquid essential oil in disk is collected into the stainless steel cylinder of sealing in time, and extraction time is 10-30 minutes, until winter jasmine, purple sieve
Blue or pink tells fragrance completion.
4. children's bacteriostatic hand sanitizer according to claim 1, it is characterised in that：The NMF is by olive oil, rice bran oil
With galam butter 1-3 by volume:1:0.5 composition.
5. children's bacteriostatic hand sanitizer according to claim 1, it is characterised in that：The chelating agent be ethylenediamine tetra-acetic acid,
Disodium ethylene diamine tetraacetate, disodium edta, ethylenediamine tetrapropionic acid, ethylenediamine tetrapropionic acid sodium salt, sodium gluconate or
One or more in sodium citrate.
6. children's bacteriostatic hand sanitizer according to claim 1, it is characterised in that：The plant antimicrobial is carried by bergamot fruit
Take thing, Herba Patriniae extract and atractylodes japonica extract compounded combination to form, bergamot berry extract, Herba Patriniae extract, pass are grey
The weight ratio of art extract is 1-2:1:1.
7. the children's bacteriostatic hand sanitizer according to claim 1 or 6, it is characterised in that：The extraction side of the plant antimicrobial
Method is, by bergamot fruit, the broken powdering of field pennycress or atractylodes japonica, to extract 2-3 hours with the 5-10 times of alcohol reflux measured, continuously
Extract three times, be then concentrated in vacuo extract solution, obtain final product.
8. the production method of children's bacteriostatic hand sanitizer as claimed in claim 1, it is characterised in that comprise the following steps：
Appropriate deionized water is added in retort, APG, glycerine, NMF, chelating agent is subsequently adding, fully stirred
Mix to being completely dissolved, with newborn acid for adjusting pH to 7.0-7.2, add natural essence, plant antimicrobial, adjusted finally by sodium chloride
Viscosity needed for, it is filling after stirring.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710125270.9A CN106727057A (en) | 2017-03-04 | 2017-03-04 | Children's bacteriostatic hand sanitizer and its production method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710125270.9A CN106727057A (en) | 2017-03-04 | 2017-03-04 | Children's bacteriostatic hand sanitizer and its production method |
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| CN106727057A true CN106727057A (en) | 2017-05-31 |
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| CN201710125270.9A Withdrawn CN106727057A (en) | 2017-03-04 | 2017-03-04 | Children's bacteriostatic hand sanitizer and its production method |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117503681A (en) * | 2023-11-17 | 2024-02-06 | 广东科盈科技有限公司 | Moisturizing, anti-wrinkle, relieving and tightening composition and cream containing same |
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| CN101684435A (en) * | 2008-09-28 | 2010-03-31 | 福建恒安集团有限公司 | Sterilization hand washing solution |
| CN102512343A (en) * | 2011-12-16 | 2012-06-27 | 罗芸 | Preparation method for flower and volcanic mud cream |
| CN104371829A (en) * | 2014-11-14 | 2015-02-25 | 雷宏师 | Method for extracting perfume and essential oil from jasmine flowers by virtue of airflow circulation method |
| CN105695131A (en) * | 2014-11-26 | 2016-06-22 | 天津普范科技开发有限公司 | Pure cotton fabric detergent |
-
2017
- 2017-03-04 CN CN201710125270.9A patent/CN106727057A/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101684435A (en) * | 2008-09-28 | 2010-03-31 | 福建恒安集团有限公司 | Sterilization hand washing solution |
| CN102512343A (en) * | 2011-12-16 | 2012-06-27 | 罗芸 | Preparation method for flower and volcanic mud cream |
| CN104371829A (en) * | 2014-11-14 | 2015-02-25 | 雷宏师 | Method for extracting perfume and essential oil from jasmine flowers by virtue of airflow circulation method |
| CN105695131A (en) * | 2014-11-26 | 2016-06-22 | 天津普范科技开发有限公司 | Pure cotton fabric detergent |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117503681A (en) * | 2023-11-17 | 2024-02-06 | 广东科盈科技有限公司 | Moisturizing, anti-wrinkle, relieving and tightening composition and cream containing same |
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Application publication date: 20170531 |