CN106726645A - One kind infiltration breast - Google Patents

One kind infiltration breast Download PDF

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Publication number
CN106726645A
CN106726645A CN201710098193.2A CN201710098193A CN106726645A CN 106726645 A CN106726645 A CN 106726645A CN 201710098193 A CN201710098193 A CN 201710098193A CN 106726645 A CN106726645 A CN 106726645A
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CN
China
Prior art keywords
skin
infiltration
quantum dot
breast
oil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710098193.2A
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Chinese (zh)
Inventor
不公告发明人
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangzhou Poly Green Chemical Technology Research Institute Co Ltd
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Guangzhou Poly Green Chemical Technology Research Institute Co Ltd
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Publication date
Application filed by Guangzhou Poly Green Chemical Technology Research Institute Co Ltd filed Critical Guangzhou Poly Green Chemical Technology Research Institute Co Ltd
Priority to CN201710098193.2A priority Critical patent/CN106726645A/en
Publication of CN106726645A publication Critical patent/CN106726645A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31Hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/342Alcohols having more than seven atoms in an unbroken chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89Polysiloxanes
    • A61K8/891Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Cosmetics (AREA)

Abstract

The present invention relates to one kind infiltration breast, including following mass percent component:NMF:8 21%, vegetable oil:3.1 11%, graphene quantum dot:1 5%, lubricant:2 10%, emulsifying agent:3 5%, stabilizer:0.8 2%.The graphene quantum dot that the present invention is used has good characterization of adsorption and the rush effect of oozing, and can adsorb the dirt and various noxious materials of skin surface, and the moist composition for being quickly rich in emulsion permeates to skin cuticula, skin corium, smooth cuticula, promote cutin metabolism, promote nutritional ingredient to import, be that skin keeps the skin wet, regulation skin water and oil balance, make skin full of elasticity, and play cleaning skin, suppress the effect of pathogenic bacteria growing, make skin more soft smooth, improve skin immunity.

Description

One kind infiltration breast
Technical field
The present invention relates to cosmetic field, a kind of infiltration breast is specifically related to.
Background technology
One perspective study carried out in China and Mexico finds that air pollution can increase sebum secretion, changes skin Fat composition, aggravation skin oxidative is damaged.Wherein, research team is studied the skin index of 349 participants in Shanghai, Result discovery, air pollution makes greasy 3 times of the increase of skin, dries aggravation 14%, while also there is vitamin E loss, skin fibre The problems such as dimension cell suffers destruction.Researcher points out that air pollutants can aggravate oxidation of the ultraviolet to skin, it might even be possible to will Ultraviolet increases " oxidative pressure " of skin nearly 3 times, but specific mechanism also needs further research confirmation.
Air pollution has three layers of injury to skin health:Ground floor injury is that particulate matter contacts skin in itself, causes top layer Sebum is aoxidized.Data show, weighed polluting day with " quick-fried table " that PM2.5 is 500, activity 8 hours, adsorb on the face out of doors About 1 gram of dust, and the weight of one piece of muffin is about 10 grams, it means that applied 1/10 piece of muffin on the face.The second layer is hindered Evil is particulate matter, organic volatile and ultraviolet synergy, causes skin barrier to be damaged.Third layer injury is thin deep skin Born of the same parents' inflammation, causes shouting pain discomfort, dries the injury of the deep layers such as furfur, inflammation.
Chinese patent application 105287248A, discloses a kind of graphene oxide infiltration breast and preparation method thereof.The invention Graphene is applied in infiltration breast first, and elaborates that Graphene kills acarid and deep layer removes the effect of acarid, but simultaneously Effect without further investigation graphene quantum dot.
The content of the invention
Present invention aim at providing a kind of infiltration breast, from graphene quantum dot reach absorption skin surface pollutant, Promote nutriment and moist composition to skin percdation and suppress the effect of pathogenic bacteria growing.
To achieve the above object, the present invention is adopted the following technical scheme that:
A kind of infiltration breast of the invention, including following mass percent component:
NMF:8-21%;
Vegetable oil:3.1-11%;
Graphene quantum dot:1-5%;
Lubricant:2.5-11.5%;
Emulsifying agent:3-5%;
Stabilizer:1.8-17%;
Preferably, in a preferred embodiment of the invention, a kind of described infiltration breast, including following mass percent Component:
NMF:12-16%;
Vegetable oil:5-9%;
Graphene quantum dot:2-4%;
Lubricant:5-8%;
Emulsifying agent:3.5-4.5%;
Stabilizer:5-14%;
In a preferred embodiment of the invention, the NMF is the mixture of Dormant oils and glycerine.
In a preferred embodiment of the invention, the vegetable oil is the mixed of hydrogenated glucose seed oil and hydrogenated jojoba oil Compound.Grape-kernel oil is " most potent free radical scavenger " by good reputation, and it can decompose lipofuscin, protects each organ, from internal Play a part of to desalinate color spot.The effect of OPC in grape-kernel oil to skin plays dual role:On the one hand it can Collagen is promoted to form appropriately crosslinked;On the other hand, VE SOD for being enriched in grape-kernel oil etc., can be effectively clear by base scavenger Except free radical, prevention skin " excessively crosslinking ".The generation of this unusual physiological situation, so as to also prevent wrinkle of skin and scar Appearance, keep skin it is moist.Grape-kernel oil procyanidins can also prevent the generation of rigid protease, suppress it Activity, prevents free radical or hard elastics proteasome degradation hardness albumen, so as to improve the health status of skin from inside.Thus change Kind skin elasticity, reduces skin disease and wrinkle, or even eliminate scar.Effect of grape-kernel oil can adjust moisture, pore refining.Portugal Grape seed oil contains the bioactivators such as abundant vitaminF, mineral matter, protein, linoleic acid.Grape-kernel oil is affine with skin Power is splendid, and for oiliness, easily the facial skin of the state such as thing long has good improvement result.In addition, grape-kernel oil has There is enhancing skin moisture-keeping function, make skin emolliency, smooth.Jojoba oil takes from simmondsia fruit.Main component is unsaturated Higher alcohol and aliphatic acid, there is good stability, are easily merged with skin, with inoxidizability free from worldly cares.In addition, jojoba oil Also containing abundant vitamin, have functions that to nourish softening skin.
In a preferred embodiment of the invention, the lubricant is isopropyl palmitate and dimethyl silicone polymer Mixture.Isopropyl palmitate can in any proportion be mixed with water.With good lubricity.There is permeability to skin.Mainly Lubricant as emulsion class cosmetics.Can assign cosmetics good screening characteristics, have preferable compatibility, Yi Beipi with skin Skin tissue is absorbed, and makes skin emolliency.Skin is preferable to the absorbability of this product, can effectively be contacted with hair follicle in cortex, penetrates into skin At layer depth, and the active component in cosmetics is brought into, give full play to active ingredient effect.This product is widely used in cosmetics In, with excellent skin care and moisture-keeping function.Can be applied to aerosol product, hair conditioner, face cream, sun-screening agent, shave In the cosmetics such as palpus cream.Dimethyl silicone polymer can be with lanolin, stearyl alcohol, cetanol, glycerin monostearate, tween, department The mixing of the surfactants such as disk is used as emulsion-type matrix.
In a preferred embodiment of the invention, the emulsifying agent be cetostearyl alcohol/cetearyl glucoside and The mixture of stearine/PEG-100 stearates.Cetostearyl alcohol/cetearyl glucoside has high security, Natural mildness, biological degradability, superpower emulsibility can emulsify the grease more than 40%, and stability is strong;And superpower compatibility, There is long-acting moisture retention, good hand touch, lotion magnetic is white, beautiful, moist, soft and smooth.Stearine/PEG-100 stearates emulsification Ability is strong, equally stablizes in the formula in acidity or containing electrolyte;And with cetostearyl alcohol/cetearyl glucoside breast Agent compounding use, both can reach satisfied effect, and the cost of formula can be substantially reduced again.
In a preferred embodiment of the invention, the stabilizer is caprylic/capric triglyceride and cetostearyl alcohol Mixture.Miglyol 812N is the high-purity grease by caprylic/capric and glycerine esterification.It is a kind of outstanding Moist grease, with good spreadability, make skin that there is smooth but not greasy sensation, be easily absorbed by the skin.To cosmetics Uniform and smooth play well effect, make skin lubrication glossy.Caprylic/capric triglyceride can be used as the base of moisturizing factor Material, the stabilizer of cosmetics, antifreezing agent, homogeneous agent.Cetostearyl alcohol has suppression greasy feeling, reduces wax class raw material stickiness, surely Determine the effect such as cosmetics gel.
British scientist has been prepared by carbon atom with sp first within 20042It is new that the monoatomic layer of hydridization connection is constituted Two-dimensional atomic crystal-Graphene, its thickness only has 0.3354nm, is to find most thin material in the world at present.Graphene oxide With low cost, raw material is easy to get, with good process based prediction model, such as specific surface energy higher, good hydrophily, good Absorption property, and have preferable dispersiveness in water and organic solvent.
Graphene quantum dot, as a kind of new quantum dot, in recent years by the extensive concern of scientist.Graphene amount Son point is the carbon nanomaterial of quasi-zero dimension, and its particle diameter is general in 10nm or so, except inheriting Graphene good water solubility, surface area Greatly, carrier mobility speed is high, mechanical flexibility is good and many premium properties such as stable optical performance outside, due to its size It is small, also with significant quantum confinement effect and edge effect, and with excellent fluorescence property, good bio-compatible The special physicochemical properties such as property, low cytotoxicity, chemical inertness.
There is graphene quantum dot of the present invention good characterization of adsorption and rush to ooze performance, can adsorb the dirt of skin surface Thing, promotes NMF and vegetable oil to be permeated in skin, and contained nutritional ingredient in infiltration breast is imported, and plays the work of cleaning skin With.Because graphene quantum dot belongs to nanometer materials, in easily swallowing abdomen by bacterium, germ, cause bacterium, germ it is dead Die, thus can play a part of to suppress the bacteria growing that causes a disease.
Beneficial effects of the present invention:Compared with prior art, a kind of infiltration breast of the invention has the following advantages that:1. graphite Alkene quantum dot has good characterization of adsorption and the rush effect of oozing, and can adsorb the dirt and various noxious materials of skin surface, quickly NMF and plant extracts are permeated to skin cuticula, skin corium, contained nutritional ingredient in infiltration breast is imported, strengthen skin Skin basalis, strengthens corium fabric, allows skin to get well state;2. graphene quantum dot and hydrogenated glucose seed oil and hydrogenate suddenly Bar oil scientific matching can smooth cuticula suddenly, dredge smooth cutin gap, allow water composition more smoothly to infiltrate into skin depth Layer, plays a part of deep layer and moistens moisturizing;3. graphene quantum dot can also play cleaning skin, suppress the work of pathogenic bacteria growing With.
Specific embodiment
With reference to specific embodiment, the present invention is described in further detail.
Embodiment 1~5
A kind of 5 specific embodiments for permeating breast of the present invention are listed in table 1.
Table 1
A kind of 5 specific comparative examples for permeating breast of the present invention are listed in table 2.
Table 2
Evaluation test on probation
For preferably prove it is provided by the present invention it is a kind of infiltration breast have excellent effect, choose embodiment 1,2,3,4, 5 and reference examples 1,2,3,4,5 carry out further on probation investigation and evaluation test.Embodiment is as follows:Choose 50 special will Hope person, age distribution is 18-58 Sui.The wherein people of male 20, the people of women 30.Evaluation test is carried out to embodiment, the examination of each sample It it is one month with the phase, it is facial drying, acne long, aging crowd to try out object.Table 3 is test index and result.
Table 3
Result shows:
For facial drying, acne long, aging crowd, the infiltration breast of long-term use graphene-containing quantum dot of the present invention, there is bright Aobvious improvement and the effect of alleviation.And embodiment 3 has the best effect for being obviously improved and alleviating, embodiment 3 is this hair Bright optimization formula.
The above, the only present invention preferably specific embodiment, but protection scope of the present invention is not limited thereto, Any one skilled in the art in the technical scope of present disclosure, the change or replacement that can be readily occurred in, Should all be included within the scope of the present invention.Therefore, protection scope of the present invention should be with the protection of claims Scope is defined.

Claims (7)

1. a kind of infiltration breast, including following mass percent component:NMF:8-21%, vegetable oil:3.1-11%, Graphene Quantum dot:1-5%, lubricant:2.5-11.5%, emulsifying agent:3-5%, stabilizer:1.8-17%.
2. a kind of infiltration breast according to claim 1, including following mass percent component:NMF:12-16%, plant Thing oil:5-9%, graphene quantum dot:2-4%, lubricant:5-8%, emulsifying agent:3.5-4.5%, stabilizer:5-14%.
3. a kind of infiltration according to claim 1 and 2 is newborn, it is characterised in that the NMF is Dormant oils and glycerine Mixture.
4. a kind of infiltration breast according to claim 1 and 2, it is characterised in that the vegetable oil be hydrogenated glucose seed oil and The mixture of hydrogenated jojoba oil.
5. a kind of infiltration breast according to claim 1 and 2, it is characterised in that the lubricant be isopropyl palmitate and The mixture of dimethyl silicone polymer.
6. a kind of infiltration according to claim 1 and 2 is newborn, it is characterised in that the emulsifying agent is cetostearyl alcohol/spermaceti The mixture of stearyl glucoside and stearine/PEG-100 stearates.
7. a kind of infiltration according to claim 1 and 2 is newborn, it is characterised in that the stabilizer is caprylic/capric glycerine three The mixture of ester and cetostearyl alcohol.
CN201710098193.2A 2017-02-22 2017-02-22 One kind infiltration breast Pending CN106726645A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107652497A (en) * 2017-09-08 2018-02-02 东莞市芬璐家居用品有限公司 A kind of formula of quantum latex
CN114423400A (en) * 2019-07-09 2022-04-29 首尔大学校产学协力团 Cosmetic composition containing graphene quantum dots as active ingredient

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103961294A (en) * 2014-05-31 2014-08-06 广州丹奇日用化工厂有限公司 Rehmannia extracting solution as well as preparation method and application thereof
CN103989602A (en) * 2014-05-31 2014-08-20 广州丹奇日用化工厂有限公司 Calanthe discolor lindl extract, as well as preparation method and application thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103961294A (en) * 2014-05-31 2014-08-06 广州丹奇日用化工厂有限公司 Rehmannia extracting solution as well as preparation method and application thereof
CN103989602A (en) * 2014-05-31 2014-08-20 广州丹奇日用化工厂有限公司 Calanthe discolor lindl extract, as well as preparation method and application thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
孙晓丹, 刘中群, 颜昊: "石墨烯量子点的制备及其生物应用", 《无机材料学报》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107652497A (en) * 2017-09-08 2018-02-02 东莞市芬璐家居用品有限公司 A kind of formula of quantum latex
CN114423400A (en) * 2019-07-09 2022-04-29 首尔大学校产学协力团 Cosmetic composition containing graphene quantum dots as active ingredient
CN114423400B (en) * 2019-07-09 2024-01-30 首尔大学校产学协力团 Cosmetic composition containing graphene quantum dots as active ingredient

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