CN1067251C

CN1067251C - Ointment for treatment of burns

Info

Publication number: CN1067251C
Application number: CN93111154A
Authority: CN
Inventors: 郭正春
Original assignee: MEDICAL TEAM SHENYANG FIRE SUB-BRIGADE CHINA PEOPLE'S ARMED POLICE UNIT
Current assignee: MEDICAL TEAM SHENYANG FIRE SUB-BRIGADE CHINA PEOPLE'S ARMED POLICE UNIT
Priority date: 1993-05-21
Filing date: 1993-05-21
Publication date: 2001-06-20
Anticipated expiration: 2013-05-21
Also published as: CN1080870A

Abstract

The present invention relates to an ointment for treating burns, which has the technical scheme that golden thread, phellodendron, atractylodes rhizome and Japanese ampelopsis root serve as a monarch, borneol serves as a minister, angelica and arnebia root serve as an assistant, and sesame oil and beeswax serve as a guide. The formula of the ointment for treating burns comprises golden thread, phellodendron, atractylodes rhizome, borneol, angelica, beeswax, sesame oil, japanese ampelopsis root and alkanna tinctoria. The ointment can alleviate the pain of a patient, reduce the disability rate, control infection, reduce scars, shorten treatment time and reduce the workload of medical care personnel. After the ointment is applied to the burnt which is strapped, a patient of activity ability is not affected and limited, and can move freely.

Description

A kind of treatment burns cream

The present invention relates to a kind of Chinese medicinal ointment, particularly a kind of Chinese medicinal ointment for the treatment of burn usefulness.

Present domestic burn treating all is to adopt traditional dry process for exposing, exposes after promptly adopting the silver sulfadiazin wound surface smearing, and uses roasting grade of lamp and promote that wound surface is dry and form a scab.Adopt the method treatment burn wound to make patient bear very big misery, maimed incidence rate height, China burn traumatic pain professor Xu Rongxiang of Science ﹠ Technology Center has invented the moistening process for exposing of a kind of burn, use moist expose burn ointment treatment burn wound, the problem of not long cicatrix or the youthful and the elderly's cicatrix after mainly solving deep and curing.This wet exposing therapy needs change dressings in per about 3 hours has once increased medical personnel's workload, and owing to need not wrap up, so in order to prevent that the ointment trickling from coming off, for can not voluntary activity behind middle homalographic and the patient of the privileged sites burn wound coating.Cold district is indoor warmingly will waste a large amount of energy.

The purpose of this invention is to provide a kind of ointment of new treatment burn, it can alleviate patient's misery, reduces disability rate, alleviates medical personnel's workload simultaneously, coating wrapping back for the patient that mobility is arranged without any influence and restriction, can activity freely.

The object of the present invention is achieved like this: this ointment is monarch with Rhizoma Coptidis, Cortex Phellodendri, Rhizoma Atractylodis, Radix Ampelopsis four Chinese medicine, Rhizoma Coptidis, Cortex Phellodendri clearing up internal heat by using drugs of bitter in taste and cold in nature, dampness pathogenic fire purging, the removing pathogenic fire is arranged, attack the merit of thermal detoxification, Rhizoma Atractylodis, the bitter wet dry temperature of Radix Ampelopsis, share with Cortex Phellodendri, heat clearing away is eliminating evil, and the power of dampness eliminating stagnation is stronger.

With the Borneolum Syntheticum is minister, and the dissipating blood stasis heat clearing away is transferred to the intramuscular pathogenic fire, anticorrosion life, pain relieving.Assistant with Radix Angelicae Sinensis, Radix Arnebiae (Radix Lithospermi), blood-nourishing blood-generating invigorate blood circulation, granulation promoting puts on flesh, and impels wound healing.With Oleum sesami, Cera Flava for making, removing the necrotic tissue and promoting granulation, Glycerin, the protection wound surface makes skin battalion defend blending, normal circulation of qi and blood, and make burn wound's quickly-healing.

Burn cream prescription of the present invention is as follows:

Rhizoma Coptidis 3-30% Cortex Phellodendri 5-18%

Rhizoma Atractylodis 2-10% Borneolum Syntheticum 4-16%

Radix Angelicae Sinensis 3-12% Cera Flava 10-25%

Oleum sesami 10-65% Radix Ampelopsis 7-15%

Radix Arnebiae (Radix Lithospermi) 1-6%.

Below all be weight percentage.

Ointment of the present invention is full Chinese medicine preparation, directly smears wound surface, adopts occlusive dressing, and tangible pain relieving, infection, promotion epithelial growth are arranged, and suppresses the outgrowth effect of connective tissue collagen fiber.The course of treatment can be shortened.Alleviate patient's misery, especially in, the patient of small size blister burn, as timely medication, can reach the effect of one-time cure.

Be the double-blind method comparing result of ointment clinical effectiveness of the present invention below;

(1), wound surface analgesic effect contrast: two form the pain relieving performance (based on patient's private prosecution) that the face analgesic effect all adopts the medicine overall process, the contrast groups wound surface has slight one property crossed analgesic effect person 7 examples, account for and observe 18.32% of case, no analgesic effect person 30 examples, account for and observe 81.08% of case, and wound surface has obvious analgesic effect person 35 examples in the clinical experiment group, account for and observe 89.74% of case, no analgesic effect person 4 examples, account for and observe 10.26% of case, thereby illustrate that there were significant differences for the wound surface analgesic effect of clinical observation group and matched group.(P＜0.01) proves that ointment of the present invention has tangible analgesic effect.

(2), wound surface control infection effect contrast: two form face has or not infection or light and heavy degree, all be medication overall process traumatic infection degree performance and decide, the matched group wound surface does not have the infected's 5 examples, accounts for 13.51% of observation case, the infected's 32 examples are arranged, account for and observe 86.49% of case.And clinical experiment is formed face and is not had the infected's 33 examples, accounts for to observe 84.62% of case, and the infected's 6 examples are arranged, and accounts for and observes 15.38% of case, illustrates that the effects of two groups of control traumatic infections have notable difference.(P＜0.01) proves that ointment of the present invention has obvious bactericidal, the effect of control infection.

(3), wound tissue pathological examination result contrast: 76 routine cases in two groups are shallow deep wound surface, by before the medication, carry out wound tissue check pathological section totally 228 histopathology sheet check results in the medication and after curing respectively.(is example with the deep); The matched group wound surface obviously is shown as cicatrix healing state, thereby prove that ointment of the present invention can not only promote epithelial growth, wound healing, shorten treatment time, and promotion respectively burn interlayer ecological organization cellular-restoring vigor and regeneration arranged, control forms the connective tissue and the effect of collagen tissue hyperplasia of cicatrix, and reaching wound surface does not have cicatrix and few cicatrix healing.Recovery reduces maimed purpose and effect near the normal skin function.

The treatment time contrast; The matched group time is: shallow average out to 12,72 days, deep average out to 38.6 days, and the treatment time of clinical observation group is shallow average out to 8.48 days, average 25 days of deep, proof uses ointment treatment blister burn of the present invention obviously to shorten treatment time, alleviates patient's painful and economic negative carrying.

In addition because the present invention is an occlusive dressing behind the employing wound surface smearing, the blanking time of changing dressings is longer, so can alleviate medical personnel's workload, alleviates the financial burden of patient family and unit, patient's activity simultaneously is not limited, all provides bigger convenience to patient and nursing staff.

Below be four specific embodiments of the present invention:

Embodiment one

Rhizoma Coptidis 3%, Cortex Phellodendri 18%, Rhizoma Atractylodis 2%, Borneolum Syntheticum 16%, Radix Angelicae Sinensis 10%, Cera Flava 25%, Oleum sesami 10%, Radix Ampelopsis 15%, Radix Arnebiae (Radix Lithospermi) 1%.

Embodiment two

Rhizoma Coptidis 30%, Cortex Phellodendri 5%, Rhizoma Atractylodis 10%, Borneolum Syntheticum 4%, Radix Angelicae Sinensis 3%, Cera Flava 25%, Oleum sesami 10%, Radix Ampelopsis 7%, Radix Arnebiae (Radix Lithospermi) 6%.

Embodiment three

Rhizoma Coptidis 3%, Cortex Phellodendri 5%, Rhizoma Atractylodis 2%, Borneolum Syntheticum 4%, Radix Angelicae Sinensis 3%, Cera Flava 10%, Oleum sesami 65%, Radix Ampelopsis 7%, Radix Arnebiae (Radix Lithospermi) 1%.

Embodiment four

Rhizoma Coptidis 7%, Cortex Phellodendri 9%, Rhizoma Atractylodis 6%, Borneolum Syntheticum 6%, Radix Angelicae Sinensis 12%, Cera Flava 10%, Oleum sesami 33%, Radix Ampelopsis 14%, Radix Arnebiae (Radix Lithospermi) 3%.

Claims

1, a kind of treatment burns cream is characterized in that with Rhizoma Coptidis, Cortex Phellodendri, Rhizoma Atractylodis, Radix Ampelopsis four Chinese medicine be monarch, is minister with the Borneolum Syntheticum, the assistant with Radix Angelicae Sinensis, Radix Arnebiae (Radix Lithospermi), with Oleum sesami, peak wax for making its prescription following (percentage by weight):

Rhizoma Coptidis 3-30% Cortex Phellodendri 5-18%

Rhizoma Atractylodis 2-10% Borneolum Syntheticum 4-16%

Radix Angelicae Sinensis 3-12% Cera Flava 10-25%

Oleum sesami 10-65% Radix Ampelopsis 7-15%

Radix Arnebiae (Radix Lithospermi) 1-6%.

2, ointment according to claim 1 is characterized in that the prescription of described ointment is: Rhizoma Coptidis 3%, Cortex Phellodendri 18%, Rhizoma Atractylodis 2%, Borneolum Syntheticum 16%, Radix Angelicae Sinensis 10%, Cera Flava 25%, Oleum sesami 10%, Radix Ampelopsis 15%, Radix Arnebiae (Radix Lithospermi) 1%.

3, ointment according to claim 1 is characterized in that described medical ointment prescription is: Rhizoma Coptidis 30%, Cortex Phellodendri 5%, Rhizoma Atractylodis 10%, Borneolum Syntheticum 4%, Radix Angelicae Sinensis 3%, Cera Flava 25%, Oleum sesami 10%, Radix Ampelopsis 7%, Radix Arnebiae (Radix Lithospermi) 6%.

4, ointment according to claim 1 is characterized in that described medical ointment prescription is: Rhizoma Coptidis 3%, Cortex Phellodendri 5%, Rhizoma Atractylodis 2%, Borneolum Syntheticum 4%, Radix Angelicae Sinensis 3%, Cera Flava 10%, Oleum sesami 65%, Radix Ampelopsis 7%, Radix Arnebiae (Radix Lithospermi) 1%.

5, ointment according to claim 1 is characterized in that described medical ointment prescription is: Rhizoma Coptidis 7%, Cortex Phellodendri 9%, Rhizoma Atractylodis 6%, Borneolum Syntheticum 6%, Radix Angelicae Sinensis 12%, Cera Flava 10%, Oleum sesami 33%, Radix Ampelopsis 14%, Radix Arnebiae (Radix Lithospermi) 3%.