CN106722390A - A kind of application of jellyfish product and jellyfish in the product for improving gut flora is prepared - Google Patents
A kind of application of jellyfish product and jellyfish in the product for improving gut flora is prepared Download PDFInfo
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- CN106722390A CN106722390A CN201611150268.9A CN201611150268A CN106722390A CN 106722390 A CN106722390 A CN 106722390A CN 201611150268 A CN201611150268 A CN 201611150268A CN 106722390 A CN106722390 A CN 106722390A
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- A—HUMAN NECESSITIES
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Abstract
The present invention provides a kind of application of jellyfish product and jellyfish in the product for improving gut flora is prepared, and the jellyfish is the jellyfish processed by desalination alum；The jellyfish is jellyfish of the aluminium content less than 10mg/kg；The product includes that jellyfish content accounts for the product of product gross mass more than 5%, and the product is medicine, health products or functional food.The invention discloses the diversity that jellyfish can significantly improve gut flora, meanwhile, the propagation of probiotics (Lactobacillus) can be promoted, the purpose of intestinal environment is improved so as to reach, and then play a part of to prevent relevant disease.
Description
Technical field
Improvement enterobacteriaceae is being prepared the present invention relates to medicine and field of health care products, more particularly to a kind of jellyfish product and jellyfish
Application in the product of group.
Background technology
There are 1000~1150 kinds of about 100,000,000,000,000 bacteriums in human body intestinal canal, be 10 times of human body cell quantity, everyone is at least
There are 160 kinds of dominant microfloras.In the gut bacteria of healthy human body, Bacteroideae and Firmicutes are more than 90%, including intend bar
Pseudomonas, general Bordetella, Porphyromonas Pseudomonas, clostridium, Clostridium leptum category, Eubacterium, Ruminococcus and newborn bar
Pseudomonas etc..The less class of other abundance has actinomyces door (Bifidobacterium and aerogenesis Collins Pseudomonas), Proteobacteria (intestines bar
Rhizobiaceae bacterium, helicobacter pylori, magnificent moral Saudi bacterium), wart germ door and methane phase Gu bacterium etc..At present, research confirms many of human body
Plant disease such as diabetes, hypertension, high fat of blood, cancer etc. all closely related with gut flora.Gut flora fermentation polysaccharides are metabolized
Product mainly has short key aliphatic acid (acetic acid, propionic acid, butyric acid etc.), gas (hydrogen, carbon dioxide, hydrogen sulfide and methane) and ammonia,
Wherein hydrogen and carbon dioxide are the main components of gas in colon.People's enteron aisle in vitro study shows that butyric acid can promote intestinal mucosa
Repair and its functional rehabilitation, while inflammatory cytokine formation is suppressed, decrease intestinal epithelial cell tumor necrosis factor
The secretion of son, plays anti-inflammatory and antitumor action.Additionally, another studies have reported that Bacteroides and (or) fusobacterium in gut flora
The change of quantity and the appearance of bacterium Uncultured bacterium clone nbw1009b01c1, may influence new
The occurrence and development of boundary Kazak hypertension.Illustrate that different gut flora spectrums can cause a disease, can also diseases prevention.However, mesh
The preceding research in terms of microbial population of animal intestinal tract is adjusted still needs to be goed deep into.
Therefore, research has medicine, health products or the functional food for improving gut flora, to protection health very
It is necessary.
Jellyfish is commonly called as being jellyfish, Shi Jing, wax and Pu fish etc. that the large-scale jellyfish in China marine site mainly includes Rhopilema hispidum Vanhoeffen, the sea of sand
Bite, rosy clouds jellyfish, the species such as many siphonohores, be the conventional food of China coast resident.It is rich in protein, mineral matter element and dimension
The nutritional ingredients such as raw element, after cleared moisture, protein content accounts for 50% of its gross dry weight or so, and fat content is extremely low,
It is a kind of healthy food of high protein and low fat.Jellyfish is not only feast delicacies, is also good medicine of curing the disease simply.Its property is salty, flat, enters
Liver kidney, can heat reliving and toxin-eliminating, softening and resolving hard mass, step-down detumescence the effects such as, and made an uproar to tracheitis, asthma, hypertension, mouth dry throat, the deficiency of Yin
Constipation etc. has certain therapeutic action.Research find, in jellyfish contained protein not only have antifatigue, preventing hypertension,
The effects such as hypotensive, additionally it is possible to strengthen the oxidation resistance of body, improve the activity of antioxidant enzyme in body.
The content of the invention
The technical problems to be solved by the invention are：A kind of jellyfish product is provided and jellyfish is based on improving the new of gut flora
Purposes.
In order to solve the above-mentioned technical problem, the technical solution adopted by the present invention is：
The present invention provides application of the jellyfish in the product for improving gut flora is prepared.
Further, the jellyfish is the jellyfish processed by desalination alum.
Further, the jellyfish is jellyfish of the aluminium content less than 10mg/kg.
Further, the product includes that jellyfish content accounts for the product of product gross mass more than 5%, and the product is medicine
Thing, health products or functional food.
Further, the medicine is the medicine of pulvis, granule, capsule, pill or oral liquid type.
Further, the health products are chewable tablet, buccal tablets, granule, tea bag, beverage tea, beverage class oral liquid
The health products of type.
Further, the functional food is the acceptable any type of food of bromatology.
Further, the functional food is solid food, liquid food or paste food.
The present invention also provides a kind of jellyfish product, and the content of jellyfish accounts for more than the 5% of the jellyfish product gross mass.
The beneficial effects of the present invention are：Present invention finds existing material --- jellyfish has the work(for improving gut flora
Energy；Find that the preventative jellyfish for giving doses can significantly improve the diversity of gut flora by zoopery, meanwhile,
The propagation of probiotics (Lactobacillus) can be promoted, the purpose of intestinal environment is improved so as to reach, and then play the related disease of prevention
The effect of disease；Product of the invention can be medicine, health products or food, including pulvis, granule, capsule, pill or oral
The product of liquid type, chewable tablet, buccal tablets, granule, tea bag, beverage tea, the product of beverage class oral liquid type, solid food,
Liquid food or paste food etc. are various informative, are suitably eaten at any time in various occasions, and customer can be according to oneself hobby selection food
With form, it is easy to carry and preserves；Product safety made by the present invention, to human body without additive.
Brief description of the drawings
Fig. 1 is agarose gel electrophoresis detection figure in the embodiment of the present invention 1.
Fig. 2 is agarose gel electrophoresis detection figure in the embodiment of the present invention 2.
Specific embodiment
It is to describe technology contents of the invention, the objects and the effects in detail, below in conjunction with implementation method and coordinates attached
Figure is explained.
Fig. 1 and Fig. 2 is refer to, the present invention provides application of the jellyfish in the product for improving gut flora is prepared.
Knowable to foregoing description, beneficial effects of the present invention are：Present invention finds existing material --- jellyfish have change
The function of kind gut flora；Find that the preventative jellyfish for giving doses can significantly improve gut flora by zoopery
Diversity, meanwhile, the propagation of probiotics (Lactobacillus) can be promoted, so as to reach improve intestinal environment purpose, and then
Play a part of to prevent relevant disease.
Further, the jellyfish is the jellyfish processed by desalination alum.
Further, the jellyfish is jellyfish of the aluminium content less than 10mg/kg.
Further, the product includes that jellyfish content accounts for the product of product gross mass more than 5%, and the product is medicine
Thing, health products or functional food.
Further, the medicine is the medicine of pulvis, granule, capsule, pill or oral liquid type.
Further, the health products are chewable tablet, buccal tablets, granule, tea bag, beverage tea, beverage class oral liquid
The health products of type.
Further, the functional food is the acceptable any type of food of bromatology.
Further, the functional food is solid food, liquid food or paste food.
The present invention also provides a kind of jellyfish product, and the content of jellyfish accounts for more than the 5% of the jellyfish product gross mass.
Embodiment 1
(1) preparation of desalination alum (dealuminzation) jellyfish of the present invention
(1) desalination alum：By food acids (such as acetic acid, citric acid) solution immersion that jellyfish mass fraction is 1%, immersion
Solid-liquid ratio (weight ratio) be 1: 5, do not stop with agitator stirring in immersion process, accelerate the speed of desalination alum, every time immersion
Soak removal is added into the edible acid solution with first time equivalent isoconcentration, so immersion 3 times after 30min, separation is gone to sea
Bite；
(2) self-dissolving：Jellyfish after desalination alum is with food acids (such as acetic acid, citric acid) solution that pH is 4.0~4.5 by 1:
5 ratio (the weight ratios of jellyfish and food acids) immersion, makes its self-dissolving, is titrated with dietary alkali (such as sodium bicarbonate) solution after self-dissolving
It is 7.0 or so to pH, obtains jellyfish solution；
(3) concentrate or be spray-dried：Above-mentioned jellyfish from solution is collected, jellyfish concentrate is made by concentrated under reduced pressure, or
Person crushes (sieving of 50 mesh) and obtains jellyfish pulvis by spray drying.
(2) influence of the jellyfish to the gut flora of normal mouse
1st, method
Take the cleaning grade KM mouse 40 that body weight is 20 ± 2g, male and female half and half, random packet, every group of 2 cages, per 10, cage.
After each group mouse adaptability is fed 7 days, corresponding gavage 1 time daily, (aluminium content is 40mg/ to continuous gavage in feed within 30 days
kg).Control group mice physiological saline gavage, given low is 10mL/ (kgd)；Test group is respectively with the jellyfish of high dose
Solution gavage, given low is 30g/ (kgd).The light and shade alternate cycle of mouse feeding environment be 12h, 24 DEG C ± 2 DEG C of room temperature,
Humidity 55% ± 5%.Each group mouse takes cervical dislocation mode to put to death mouse after correspondence gavage terminates, and takes 2~3cm length
Mouse caecum, in -80 DEG C preservation.Mouse caecum sample carries out DNA extractions first, with fluorescent quantitative PCR 16s rRNA
338F and 806R fragments, with Illumina MiSeq platforms be sequenced, detect mouse intestinal flora diversity.
2nd, result
2.1PCR amplifications
As shown in Fig. 1 and table 1, what wherein Fig. 1 was represented is that 2% agarose gel electrophoresis detection PCR is produced to PCR amplifications
Thing, the electrophoretogram obtained by 3 μ L sample detections；What table 1 was represented is the result of PCR amplifications.
The PCR amplifications of table 1
2.2 diversity analysis and taxology are constituted
OTU (Operational Taxonomic Units) be in phylogenetics or population genetic study, in order to
Analysis is convenient for, the same mark for artificially being set to some taxon (strain, category, kind, packet etc.).It is to be understood that one
The information of number such as strain, Pseudomonas in sample sequencing result, it is necessary to categorizing operation (cluster) is carried out to sequence.By returning
Generic operation, many groups are classified as by sequence according to mutual similitude point, and a group is exactly an OTU.Can be according to different
All sequences are carried out OTU divisions by similarity level, and the generally OTU under 97% similar level carries out biological information statistics
Analysis, diversity indices is as shown in table 2.
The diversity indices of table 2
As shown in Table 2, in the diversity indices of test group, OTU values, bacterium colony abundance Index A CE, index Chao are all higher than
Control group；Shannon values are also test group more than control group, and Simpson values to be then control group be more than test group, Shannon
Value is bigger, and Simpson values are smaller, show that the diversity of gut flora is higher, therefore the jellyfish solution of gavage high dose is to enriching just
The gut flora diversity of normal mouse has facilitation.
Taxology composition research to normal mouse caecum bacterium colony finds that the colony structure composition of test group and control group exists
Door level on and no significant difference；And the colony structure composition research in category level shows, test group is compared to control group
Speech, the quantity of Lactobacillus (probiotics) substantially increases, and illustrating the jellyfish solution of gavage high dose can promote probiotics
Propagation, improves intestinal environment.
Embodiment 2
(1) preparation of desalination alum (dealuminzation) jellyfish of the present invention
(1) desalination alum：By food acids (such as acetic acid, citric acid) solution immersion that jellyfish mass fraction is 1%, immersion
Solid-liquid ratio (weight ratio) be 1: 5, do not stop with agitator stirring in immersion process, accelerate the speed of desalination alum, every time immersion
Soak removal is added into the edible acid solution with first time equivalent isoconcentration, so immersion 3 times after 30min, separation is gone to sea
Bite；
(2) self-dissolving：Jellyfish after desalination alum is with food acids (such as acetic acid, citric acid) solution that pH is 4.0~4.5 by 1:
5 ratio (the weight ratios of jellyfish and food acids) immersion, makes its self-dissolving, is titrated with dietary alkali (such as sodium bicarbonate) solution after self-dissolving
It is 7.0 or so to pH, obtains jellyfish solution；
(3) concentrate or be spray-dried：Above-mentioned jellyfish from solution is collected, jellyfish concentrate is made by concentrated under reduced pressure, or
Person crushes (sieving of 50 mesh) and obtains jellyfish pulvis by spray drying.
(2) influence of the jellyfish to the gut flora of aluminium enrichment mouse
1st, method
1.1 aluminium are enriched with the foundation of mouse model
Preliminary experiment determines the AlCl that concentration is 80mg/kg3Solution builds aluminium enrichment mouse model.Each group mouse adapts to
Property feed 7 days after, gavage AlCl3Solution, given low is 20mL/ (kgd), continuous gavage 14 days.Every 3 days, docking
Take blood once, determine blood aluminium content, its blood aluminium content stabilization is in 7~10 μ g/L.
1.2 mice groups and processing mode
The cleaning grade KM mouse 50 that body weight is 20 ± 2g are taken, male and female half and half are randomly divided into A, B, C, D, E group, every group 2
Cage, per 5, cage.The daily gavage of B, C, D group mouse 1 time, continuous gavage 14 days.Wherein, B groups physiological saline gavage, gavage agent
Measure is 10mL/ (kgd)；C groups high dose jellyfish solution gavage, given low is 30g/ (kgd)；D groups dimercapto third
Sodium sulfonate solution (300mg/kg) gavage, given low is 20mL/ (kgd)；The jellyfish homogenate gavage of E group high doses 14 days
Afterwards, then normally raise 7 days.The light and shade alternate cycle of mouse feeding environment is 12h, 24 DEG C ± 2 DEG C of room temperature, humidity 55% ± 5%.
After the completion of aluminium enrichment mouse model builds, A groups take cervical dislocation mode to put to death mouse, take the mouse caecum of 2~3cm length,
In -80 DEG C of preservations.Remaining each group mouse takes same mode to take mouse caecum after correspondence gavage terminates, in -80 DEG C of guarantors
Deposit.Mouse caecum sample carries out DNA extractions first, with 338F the and 806R fragments of fluorescent quantitative PCR 16s rRNA, uses
Illumina MiSeq platforms are sequenced, and detect the diversity of mouse intestinal flora.
2nd, result
2.1PCR amplifications
As shown in Fig. 2 and table 3, what wherein Fig. 2 was represented is that 2% agarose gel electrophoresis detection PCR is produced to PCR amplifications
Thing, the electrophoretogram obtained by 3 μ L sample detections；What table 3 was represented is the result of PCR amplifications.
The PCR amplifications of table 3
2.2 diversity analysis and taxology are constituted
OTU (Operational Taxonomic Units) be in phylogenetics or population genetic study, in order to
Analysis is convenient for, the same mark for artificially being set to some taxon (strain, category, kind, packet etc.).It is to be understood that one
The information of number such as strain, Pseudomonas in sample sequencing result, it is necessary to categorizing operation (cluster) is carried out to sequence.By returning
Generic operation, many groups are classified as by sequence according to mutual similitude point, and a group is exactly an OTU.Can be according to different
All sequences are carried out OTU divisions by similarity level, and the generally OTU under 97% similar level carries out biological information statistics
Analysis, diversity indices is as shown in table 4.
The diversity indices of table 4
As shown in Table 4, each index of C groups (high dose jellyfish group) is superior to other test groups, and its Shannon value is most
Greatly, and Simpson values are minimum, show the diversity highest of its gut flora, therefore the jellyfish solution of gavage high dose is to enriching aluminium
The gut flora diversity for being enriched with mouse has facilitation.
Taxology composition research to aluminium enrichment mouse caecum bacterium colony finds, in the Bacterial community composition analysis of door level
In, the topmost flora of each group is Firmicutes；And the colony structure composition research in category level shows, gavage high dose
Jellyfish solution compared to gavage physiological saline group, its Lactobacillus (probiotics) quantity is significantly improved, so as to illustrate gavage
High dose jellyfish solution can promote the propagation of probiotics, improve intestinal environment.
Can be drawn from embodiment 1 and embodiment 2：The jellyfish of gavage doses have be obviously improved normal mouse and aluminium
The function of mouse intestinal flora is enriched with, promotes the propagation of probiotics (such as Bacillus acidi lactici), improve intestinal environment.Illustrate jellyfish in system
Had broad application prospects on the standby product for improving gut flora.
Embodiment 3 has the medicine powder containing jellyfish for improving gut flora
1st, by formula rate, by (30 parts) mixing 8min of cycloheptaamylose (10 parts) and jellyfish pulvis, jellyfish powder must be embedded
Agent；
2nd, D-mannital (50 parts), maltodextrin (30 parts), microcrystalline cellulose (30 parts), oligomeric is weighed respectively in proportion
Xylose (15 parts), isomalt (15 parts), WPC (15 parts), (3 parts) crushing of citric acid, cross 100 mesh sieves, so
Mix 8min and obtain final product powder medicine with embedding jellyfish pulvis, beta carotene (3 parts), milk flavour (3 parts), magnesium stearate (3 parts) afterwards
Thing.
This implementation component is in parts by weight.
Embodiment 4 has the granules medicine or health products containing jellyfish for improving gut flora
1st, D-mannital (5 parts), maltodextrin (5 parts), microcrystalline cellulose (5 parts), oligomeric wood are weighed respectively in proportion
Sugared (3 parts), isomalt (3 parts), WPC (3 parts), milk flavour (0.1 part), cross 80 mesh sieves after crushing, mix
Close 10min and obtain mixed powder；
2nd, by citric acid (0.1 part), beta carotene (0.01 part) is soluble in water is made the aqueous solution, used as adhesive；
3rd, to adding above-mentioned adhesive to be made softwood in above-mentioned mixed powder, pelletized with 16 mesh sieves, obtain wet granular, put microwave and do
Dry 5min in dry machine, and with the quick whole grain of 16 mesh sieves；
4th, by (5 parts) mixing 8min of cycloheptaamylose (1 part) and jellyfish pulvis, jellyfish pulvis must be embedded；
5th, whole good particle mix 8min with embedding jellyfish pulvis, magnesium stearate (0.1 part), after being well mixed, packs, close
Envelope obtains final product granules medicine or granule health products.
This implementation component is in parts by weight.
Embodiment 5 has the capsule containing jellyfish for improving gut flora
1st, D-mannital (35 parts), maltodextrin (20 parts), microcrystalline cellulose (20 parts), oligomeric is weighed respectively in proportion
Xylose (11 parts), isomalt (11 parts), WPC (11 parts), milk flavour (2.5 parts), cross 80 mesh after crushing
Sieve, mixing 10min obtains mixed powder；
2nd, by citric acid (2.5 parts), beta carotene (2 parts) is soluble in water is made the aqueous solution, used as adhesive；
3rd, to adding above-mentioned adhesive to be made softwood in above-mentioned mixed powder, pelletized with 16 mesh sieves, obtain wet granular, put microwave and do
Dry 5min in dry machine, and with the quick whole grain of 16 mesh sieves；
4th, by (20 parts) mixing 5-10min of cycloheptaamylose (5 parts) and jellyfish pulvis, jellyfish pulvis must be embedded；
5th, whole good particle mixes 8min with embedding jellyfish pulvis, magnesium stearate (2.5 parts), after being well mixed, fills grain, choosing
Capsule, polishing, is made pharmaceutical capsules.
This implementation component is in parts by weight.
Embodiment 6 has the pill medicine containing jellyfish for improving gut flora
1st, by formula rate, by (15 parts) mixing 8min of cycloheptaamylose (3 parts) and jellyfish pulvis, jellyfish powder must be embedded
Agent；
2nd, D-mannital (15 parts), maltodextrin (15 parts), microcrystalline cellulose (15 parts), oligomeric is weighed respectively in proportion
Xylose (9 parts), isomalt (9 parts), WPC (9 parts), (2 parts) crushing of citric acid, cross 100 mesh sieves, then
Mix with embedding jellyfish pulvis, beta carotene (1.5 parts), milk flavour (2 parts), magnesium stearate (2 parts), starch (2 parts), use
Water pill, puts drying in microwave dryer, obtains final product pill medicine.
This implementation component is in parts by weight.
Embodiment 7 has the oral liquid containing jellyfish for improving gut flora
A certain amount of jellyfish pulvis (1 part) is weighed, by 1:5 ratio is dissolved in water (5 parts), adds FOS (5.5
Part) stir after add ferrous gluconate (0.0018 part), zinc gluconate (0.0009 part), calcium gluconae
(0.18 part), fully dissolves and is filtered to remove insoluble impurities, is filled to sealing in 10mL oral liquid bottles, obtains extra large after sterilizing cooling
Bite pulvis oral liquid.
This implementation component is in parts by weight.
Embodiment 8 has the chewable tablet containing jellyfish, the buccal tablets for improving gut flora
Weigh a certain amount of jellyfish pulvis (25 parts), natural VE (2 parts), milk powder (85 parts), maltodextrin (200
Part) and converted starch (85 parts)；Various raw materials are well mixed according to a certain percentage, allotment, by making soft material, granulation, dry, whole
The Conventional process steps such as grain, compressing tablet, sterilizing and packaging, that is, be made chewable tablet or buccal tablets, every about 1.5g.
This implementation component is in parts by weight.
Embodiment 9 has the tea bag containing jellyfish for improving gut flora
1st, 100 portions of commercially available excellent green tea tealeaves are weighed, 12~20 mesh sieves was crushed with pulverizer, removed without crushing
Bulky grain, after 40~50 mesh sieves, removes tealeaves fine powder, obtains green tea powder；
2nd, 30 parts of the green tea powder of step 1 acquisition is taken, is mixed with 4.5 parts of jellyfish pulvis；
3rd, the tealeaves and the mixing powder of jellyfish powder for obtaining step 2 are placed in air blast Constant Temp. Oven and dry, and dry
Tea bag health products are both obtained after dry through sterilized, pack (2~3g/ bags) again.
This implementation component is in parts by weight.
Embodiment 10 has the beverage class I liquid I food containing jellyfish for improving gut flora
Jellyfish pulvis is pressed 1:10 ratio is dissolved in a certain amount of pure water, such as weighs 100 parts of jellyfish pulvis, molten
Solution adds flavoring essence (1.4 parts), white granulated sugar (100 parts), citric acid (1.6 parts), citric acid in 1000 parts of pure water
The composition, mistake after stirring such as sodium (0.5 part), Sodium Benzoate (0.3 part), lemon yellow (0.2 part), carmine (0.2 part)
Insoluble impurities is filtered, and using ultraviolet sterilization, sterile filling technique, sealing both obtains finished product.
This implementation component is in parts by weight.
Embodiment 11 has the solid food containing jellyfish for improving gut flora
Such as biscuit, white granulated sugar (20 parts) will be added after (50 parts) softenings of butter, stirred, sequentially add egg (40
Part), jellyfish powder (10 parts), Self- raising flour (200 parts), and add a small amount of water, be kneaded into dough after stirring, according to thickness and
Shape is pressed into pie, using tool making into the biscuit of certain specification, is finally putting into baking box.
This implementation component is in parts by weight.
Embodiment 12 has the paste food containing jellyfish for improving gut flora
Such as sesame cream, crushed with pulverizer after (15 parts) mixing of the sesame that will be fried (20 parts) and glutinous rice, and add appropriate
Jellyfish pulvis (10 parts), fully mix after both finished product.When edible, take in right amount with water together infusion into pasty state, can be by adding
Plus white sugar (3 parts) or honey (1 part) assign its sweet taste.
This implementation component is in parts by weight.
In sum, present invention discover that jellyfish has the function of improving gut flora；Found by zoopery preventative
The jellyfish for giving doses can significantly improve the diversity of gut flora, meanwhile, probiotics (Lactobacillus) can be promoted
Propagation, so as to reach improve intestinal environment purpose, and then play a part of prevent relevant disease；Product of the invention can be with
Medicine, health products or food, including pulvis, granule, capsule, pill or oral liquid type product, chewable tablet, buccal tablets,
The forms such as granule, tea bag, beverage tea, the product of beverage class oral liquid type, solid food, liquid food or paste food are more
Sample, suitably eats at any time in various occasions, and customer can be easy to carry and preserve according to oneself edible form of hobby selection；This hair
Bright made product safety, to human body without additive.
Embodiments of the invention are the foregoing is only, the scope of the claims of the invention is not thereby limited, it is every to utilize this hair
The equivalents that bright specification and accompanying drawing content are made, or the technical field of correlation is directly or indirectly used in, similarly include
In scope of patent protection of the invention.
Claims (9)
1. application of the jellyfish in the product for improving gut flora is prepared.
2. application of the jellyfish according to claim 1 in the product for improving gut flora is prepared, it is characterised in that described
Jellyfish is the jellyfish processed by desalination alum.
3. application of the jellyfish according to claim 1 in the product for improving gut flora is prepared, it is characterised in that described
Jellyfish is jellyfish of the aluminium content less than 10mg/kg.
4. application of the jellyfish according to claim 1 in the product for improving gut flora is prepared, it is characterised in that described
Product includes that jellyfish content accounts for the product of product gross mass more than 5%, and the product is medicine, health products or functional food.
5. application of the jellyfish according to claim 4 in the product for improving gut flora is prepared, it is characterised in that described
Medicine is the medicine of pulvis, granule, capsule, pill or oral liquid type.
6. application of the jellyfish according to claim 4 in the product for improving gut flora is prepared, it is characterised in that described
Health products are the health products of chewable tablet, buccal tablets, granule, tea bag, beverage tea or beverage class oral liquid type.
7. application of the jellyfish according to claim 4 in the product for improving gut flora is prepared, it is characterised in that described
Functional food is the acceptable any type of food of bromatology.
8. application of the jellyfish according to claim 4 in the product for improving gut flora is prepared, it is characterised in that described
Functional food is solid food, liquid food or paste food.
9. a kind of jellyfish product, it is characterised in that the content of jellyfish accounts for more than the 5% of the jellyfish product gross mass.
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