CN106692784A - Health-care medicated diet for large-intestine dampness-heat ulcerative colitis - Google Patents
Health-care medicated diet for large-intestine dampness-heat ulcerative colitis Download PDFInfo
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- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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Abstract
The invention discloses a health-care medicated diet for auxiliary prevention and treatment of large-intestine dampness-heat ulcerative colitis. The medicated diet is formed by two fixed combinations of a formula medicated diet and an intense humid type or intense heat type tea formula, wherein the fixed combinations use a formula A which consists of 20 parts of purslane herbs, 20 parts of lactuca indica, 20 parts of herba scutellariae barbatae, and 15 parts of sanguisorba, and a formula B which consists of 20 parts of raw pearl barley, 20 parts of radix codonopsis, 20 parts of glabrous greenbrier rhizomes, and 20 parts of Chinese yams. The intense heat type tea formula consists of 8 parts of honeysuckle flowers and 8 parts of chrysanthemums, and the intense humid type formula consists of 10 parts of flos gossampini and 8 parts of lotus leaves. Experiments prove that leading indicators of the cure rate, the total effective rate and the life quality of a group of people after eating the health-care medicated diet are apparently higher than those of a conventional group. Side effects and discomfortableness of people due to conventional medication, retention enema, and long-term oral administration of traditional Chinese medicines can be reduced, the treatment compliance is improved, and the health-care medicated diet is suitable for long-term maintenance treatment for the large-intestine dampness-heat ulcerative colitis. The materials of the medicated diet are convenient to take, and the health-care medicated diet is low in cost and convenient to use, has an exact auxiliary treatment effect and is free from side effects.
Description
Technical field
The present invention relates to a kind of health care medicated food formula for aiding in prophylactic treatment Damp-heat syndrome ulcerative colitis.
Background technology
Ulcerative colitis (Ulcerativecolitis UC) is diffused chronic a kind of agnogenic knot, rectum
Nonspecific inflammatory disease.Lesion is mainly limited to the mucous membrane and submucosa of large intestine, and its clinic is mainly shown as diarrhoea, sticks
Liquid pus and blood stool, stomachache and it is tenesmus.The traditional Chinese medical science thinks that the primary symptom of Damp-heat syndrome ulcerative colitis is：Stomachache, diarrhoea, just
Lower mucus purulence blood；Red tongue body, yellow and greasy fur.Secondary disease：It is burning sensation of the anus, tenesmus；Scanty drak urine；Dry mouth with bitter taste, halitosis.Main point
Heat is very as type and wet very as type.Finding colorectal mucosa congestion and edema and there is rotten to the corn person then by clinical experience for many years, under Sigmoidoscope
It is referred to as hot very as type；Finding patient colorectal mucosa attachment mucus is more under Sigmoidoscope, and being referred to as slippery and rapid pulse is wet very as type.Disease disease
Journey is long, recurrent exerbation, protracted course of disease.
Current ulcerative colitis western medical treatment is with aminosalicylic acid, antibiotic and from immunoloregulation function, intestinal mucosa
The aspects such as function, inflammatory mediator suppression are set about, and clinic has certain curative effect, but drug side-effect is obvious.It is to use that clinic is generally conventional
Sulfasalazine is treated.Chinese traditional treatment stress colonic mucosa reparation, from reduce drug side-effect, reduce recurrence rate
Studied etc. number of ways.The routine care of ulcerative colitis is mainly health propaganda and education and diet is nursed.Damp-heat syndrome
Ulcerative colitis belongs to chronic disease, is guidance with theory of traditional Chinese medical science, adds with reference to herbal cuisine give improvement in the treatment, can be to the disease
Treatment has facilitation.But there is presently no related research.
The content of the invention
To overcome disadvantages described above, the present invention to disclose a kind of health care herbal cuisine for Damp-heat syndrome ulcerative colitis, institute
State herbal cuisine and be applied in combination formula including A and two kinds of B, the formulas of A according to the mass fraction are：20 parts of purslane, 15 parts of garden burnet, field pennycress
20 parts, 20 parts of Sculellaria barbata；B is formulated：20 parts of Semen Coicis, 20 parts of Radix Codonopsis, 20 parts of smilax, 20 parts of Chinese yam.
Two kinds described of A and B is applied in combination formula for soup type meals, or congee type meals；The preparation of described soup type meals
Method is：Two kinds of formulas of A and B is added water respectively and be brewed into thick soup with meat；The preparation method of congee type meals is：By A and two kinds of B
Formula goes the dregs of a decoction, plus bright rice to be brewed into congee after adding water to cook respectively.A is drunk in daily one after the other or two kinds of B is formulated what is boiled
Thick soup or congee.
The present invention, according to the difference of microcosmic symptom, is divided into heat very as type large intestinal damp-heat according to microcosmic dialectical treatment method
Ulcerative colitis, and it is wet very as type large intestinal damp-heat ulcerative colitis.Finding colorectal mucosa congestion and edema and have under Sigmoidoscope
Rotten to the corn person is then referred to as heat very as type；Finding patient colorectal mucosa attachment mucus is more under Sigmoidoscope, the referred to as wet very elephant of slippery and rapid pulse
Type.
For heat very as type large intestinal damp-heat ulcerative colitis, on the basis of above A, B formula, then coordinate by honeysuckle
The heat that 8 parts and 8 parts of chrysanthemum are constituted is made tea with drink very as type tea side.
For wet very as type large intestinal damp-heat ulcerative colitis, on the basis of above A, B formula, then coordinate by common bombax flower
10 parts wet very as type tea side with 8 parts of compositions of lotus leaf, makes tea with drink.
Beneficial effect：Tests prove that meals group cure rate of applying of the invention is 12.7%, total effective rate is 92.7%.It is conventional
The cure rate for the treatment of group is 5.5%, and total effective rate is 81.8%, applies meals group cure rate and total effective rate obviously higher than routine
Group.The quality of life leading indicator for applying meals group includes physiological function, social function, limitation, the heart of the physiological problem to daily routines
Reason problem is significantly better than that conventional therapy group to the limitation of social activities, mental health, vigor and general health evaluation.Using this
Invention herbal cuisine diet nurses the clinical efficacy that can improve Damp-heat syndrome patients of ulcerative colitis；Improve the life of this patient
Quality；Reduction was treated this disease and used drug retention enema, the side effect of Long-term Oral Chinese medicine and sense of discomfort in the past；Improve treatment
Compliance, is adapted to this sick long term maintenance therapy.And herbal cuisine convenient material drawing, with low cost, easy to use, auxiliary curative effect is definite,
Have no side effect.
Specific embodiment
Below in conjunction with specific embodiment, the present invention is described further.
First, test method：
1st, clinical data
Experiment patient：Certain city's traditional Chinese medical science Out-patient Department and the people of Damp-heat syndrome patients of ulcerative colitis 110 of inpatient department's treatment,
Patient is divided into conventional group at random using lottery and each 55 people of meals group is applied, inclusive criteria was with reference to Chinese Medical Association's digestion in 2012
Sick credit meeting IBD group revision《China's diagnosis status of inflammatory bowel disease and the National Consensus treated》And differential diagnosis in tcm is
Light, the medium-sized patients of ulcerative colitis of Damp-heat syndrome.Its Standards of Chinese Medical Syndrome Differentiation was with reference to revision in 2010《Ulcerative colitis
Scorching traditional Chinese medical science diagnosis and treatment National Consensus》Middle Damp-heat syndrome patient.These cases carry out the traditional Chinese medical science by the intestines mirror traditional Chinese physician for curing mainly the above
Debate knowledge, and Pass Test condition.
Wherein conventional group：Man 29, female 26, age 15-48 Sui；The course of disease 4~11.7 months, average course of disease 6.9 months.Apply meals
Group：Man 28, female 27, age 14-49 Sui；4.1~December of the course of disease, average course of disease 7.1 months.Two groups of patient ages, sex structures
Into than, indices such as the course of disease, the order of severity of the state of an illness and schooling, through statistical analysis, difference is not statistically significant,
With comparativity.
2nd, method
2.1 conventional groups：Western medicine routine treatment：The each 1g of sulfasalazine (SASP), three times a day orally.(SASP batches
Number：Chinese medicines quasi-word H31020557, Shanghai Xinyi Jiahua Pharmaceutical Co., Ltd. production) January be 1 course for the treatment of, be used in conjunction 6 courses for the treatment of.
Patients with active fully rests, few slag, light, diet；Stationary phase appropriate exercise, light, soft, easy to digest, eutrophy of taking food
Food, avoids the product of pungent, stimulation, avoids the stiff food of shrimp crab.
2.2 apply meals group：Implement the dialectical meals diet of applying of traditional Chinese medical science macro and micro on the basis of observation group to nurse.
2.2.1 the dialectical meals medicated food formula of applying of traditional Chinese medical science macroscopic view includes：A is formulated by purslane, garden burnet, field pennycress and Sculellaria barbata；B
Formula includes Semen Coicis, Radix Codonopsis, smilax and Chinese yam.
2.2.2 the traditional Chinese medical science is microcosmic dialectical applies meals inventory：The side of making tea-heat is very as type includes honeysuckle and chrysanthemum with C1 side；It is wet very
As type includes common bombax flower and lotus leaf with C2 side.
2.3 macro and micros are dialectical to apply the specific method that meals are nursed
2.3.1 thick soup or the congee that A or B recipe sides are brewed into are drunk in daily one after the other.It is boiled into lean meat 200g when stewing soup
200mL thick soups.When cooking gruel water double to remove slag take 400ml plus bright rice cook gruel it is edible.Make tea and boil boiling water, part vic with 200ml.
2.3.2 the traditional Chinese medical science it is microcosmic it is dialectical be to be debated according to the local micro-variations collocation macroscopic view of finding patient colorectal mucosa under intestines mirror
Card is applied meals side and is made tea and takes, and finding colorectal mucosa congestion and edema and has rotten to the corn person to be referred to as heat very elephant such as under Sigmoidoscope, heat very as
The side of making tea uses C1 side；What finding patient colorectal mucosa attachment mucus was more under Sigmoidoscope is referred to as wet very elephant, and the side of making tea uses C2
Side.
2.3.3 Damp-heat syndrome patients of ulcerative colitis macro and micro is dialectical applies the specific method that meals are nursed：Heat very elephant
Patient alternately takes A or B recipe side+C1 sides and makes tea and takes；It is wet very to be made tea clothes as patient alternately takes A or B recipe side+C2 sides
With.
2.3.4 the dialectical meals side that applies of macro and micro must drink five times in one week.January is 1 course for the treatment of, totally 6 courses for the treatment of.
2.4 observation index with evaluate 6 courses for the treatment of of treatment and nursing after the clinical therapeutic efficacy and quality of life of patient are carried out
Effect assessment.
2.4th, 1 criterion of therapeutical effect：According to《Ulcerative colitis combination of Chinese tradiational and Western medicine diagnosis and treatment project (draft)》Draft.Cure：Face
Bed symptom disappears, and stool shaping (daily 1-2 times), colonoscopy shows that intestinal mucosa is normal；It is effective：Symptom disappears substantially, stool
Shaping (daily 2-3 times), colonoscopy shows that intestinal mucosa ulcer and inflammation are clearly better；Effectively：Symptom mitigation, colonoscopy
Show that ulcer reduces and inflammation mitigates；It is invalid：Symptom is unchanged, and colonoscopy shows that intestinal mucosa is unchanged or aggravates.Total effective rate
=(recovery from illness+effective+effectively)/total case load.
2.4th, 2 Evaluation on quality of life：From the Chinese edition of the World Health Organization's " life quality measure table ", using questionnaire type
Investigation method, carries out the assessment of quality of life respectively after patient's treatment and nursing, and evaluation index includes：Physiological function, social work(
Energy, physiological problem are to the limitation of daily routines, at heart limitation, mental health, vigor, pain, totality of the problem to daily routines
8 dimensions such as evaluation are evaluated.Each dimension is 0 point~100 points, and score person's quality of life high is good[8]
2.5 statistical methods are analyzed using SPSS13.0 statistical softwares, and measurement data uses mean ± standard deviationRepresent, and processed with t test statisticses method, enumeration data uses chi-square criterion, P<0.05 has statistics to anticipate for difference
Justice.
Embodiment 1
Apply the medicated food formula of meals group 1：
A is formulated：Purslane 20g, garden burnet 15g, field pennycress 20g, Sculellaria barbata 20g；
B is formulated：Semen Coicis 20g, Radix Codonopsis 20g, smilax 20g, Chinese yam 20g；
C1 is formulated：Honeysuckle 8g, chrysanthemum 8g；C2 is formulated：Common bombax flower 10g, lotus leaf 8g.
By carrying out testing measure and evaluation under above-mentioned test method.
Embodiment 2
Apply the medicated food formula of meals group 2：
A is formulated：Purslane 10g, garden burnet 5g, field pennycress 30g, Sculellaria barbata 10g；
B is formulated：Semen Coicis 35g, Radix Codonopsis 10g, smilax 30g, Chinese yam 30g；
C1 is formulated：Honeysuckle 20g, chrysanthemum 5g；C2 is formulated：Common bombax flower 20g, lotus leaf 20g.
By carrying out testing measure and evaluation under above-mentioned test method.
Embodiment 3
Apply the medicated food formula of meals group 3：
A is formulated：Purslane 30g, garden burnet 25g, field pennycress 10g, Sculellaria barbata 30g；
B is formulated：Semen Coicis 10g, Radix Codonopsis 35g, smilax 10g, Chinese yam 10g；
C1 is formulated：Honeysuckle 5g, chrysanthemum 5g；
C2 is formulated：Common bombax flower 5g, lotus leaf 10g.
By carrying out testing measure and evaluation under above-mentioned test method.
2nd, result：
1st, the comparing of test group patient clinical curative effect, is shown in Table 1.
Table 1
The cure rate of conventional group is 5.5%, and total effective rate is 81.8%, and it is 12.7%, total effective rate to apply the cure rate of meals group 1
It is 92.7%；It is 5.5% to apply the cure rate of meals group 2, and total effective rate is 85.4%；The cure rate 7.3 of meals group 3 is %, and total effective rate is
83.6%；Embodiment 1 applies comparing difference between meals group cure rate and total effective rate apparently higher than conventional group and other embodiment group, group
Statistically significant (P<0.05).
3.2 test group patients ' life qualities are relatively shown in Table 2.
Table 2
Apply meals group quality of life and be substantially better than conventional group, the statistically significant (P of comparing difference between group<0.05).
Claims (2)
1. a kind of health care herbal cuisine for Damp-heat syndrome ulcerative colitis, it is characterised in that the herbal cuisine includes A and two kinds of B
, using formula and dialectical tea side, the formulas of A according to the mass fraction are by 20 parts of purslane, 15 parts of garden burnet, 20 parts of field pennycress for fixed Combination
With 20 parts of compositions of Sculellaria barbata；B formulas are made up of 20 parts of 20 parts of Semen Coicis, 20 parts of Radix Codonopsis, 20 parts of smilax and Chinese yam；It is described dialectical
Tea side point heat is wet wherein hot very as type tea side is made up of 8 parts of 8 parts of honeysuckle and chrysanthemum very as type tea side and wet very as type tea side
Very as type tea side is made up of 8 parts of 10 parts of common bombax flower and lotus leaf.
2. herbal cuisine as claimed in claim 1, it is characterised in that two kinds described of A and B is applied in combination formula for soup type meals,
Or congee type meals；The preparation method of described soup type meals is：Two kinds of formulas of A and B is added water respectively and be brewed into thick soup with meat；
The preparation method of congee type meals is：The dregs of a decoction, plus bright rice are gone to be brewed into congee after two kinds of formulas of A and B are added water to cook respectively.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107897267A (en) * | 2017-12-15 | 2018-04-13 | 柳州飞升鹏科技有限公司 | A kind of health-care moon cake and preparation method thereof |
| CN108813299A (en) * | 2018-05-16 | 2018-11-16 | 浙江省中医药研究院 | A kind of instant porridge and preparation method thereof restoring patients of ulcerative colitis enteron aisle |
| CN109287921A (en) * | 2018-09-29 | 2019-02-01 | 首益特殊医学用途配方食品科技研究（北京）有限公司 | Diet therapy nutritional element solid beverage and preparation method thereof for inflammatory bowel disease |
| CN114558026A (en) * | 2022-01-20 | 2022-05-31 | 浙江大学医学院附属第一医院 | Application of barbat skullcap polysaccharide in preparing medicine for treating inflammatory bowel disease |
-
2017
- 2017-01-10 CN CN201710017932.0A patent/CN106692784A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107897267A (en) * | 2017-12-15 | 2018-04-13 | 柳州飞升鹏科技有限公司 | A kind of health-care moon cake and preparation method thereof |
| CN108813299A (en) * | 2018-05-16 | 2018-11-16 | 浙江省中医药研究院 | A kind of instant porridge and preparation method thereof restoring patients of ulcerative colitis enteron aisle |
| CN109287921A (en) * | 2018-09-29 | 2019-02-01 | 首益特殊医学用途配方食品科技研究（北京）有限公司 | Diet therapy nutritional element solid beverage and preparation method thereof for inflammatory bowel disease |
| CN114558026A (en) * | 2022-01-20 | 2022-05-31 | 浙江大学医学院附属第一医院 | Application of barbat skullcap polysaccharide in preparing medicine for treating inflammatory bowel disease |
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