CN106692762A - Composition for preventing and treating grass carp red skin disease - Google Patents

Composition for preventing and treating grass carp red skin disease Download PDF

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Publication number
CN106692762A
CN106692762A CN201710126170.8A CN201710126170A CN106692762A CN 106692762 A CN106692762 A CN 106692762A CN 201710126170 A CN201710126170 A CN 201710126170A CN 106692762 A CN106692762 A CN 106692762A
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Prior art keywords
parts
grass carp
composition
red skin
preventing
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CN201710126170.8A
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Chinese (zh)
Inventor
苏金武
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Changsha Ruiduokang Biotechnology Co Ltd
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Changsha Ruiduokang Biotechnology Co Ltd
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Priority to CN201710126170.8A priority Critical patent/CN106692762A/en
Publication of CN106692762A publication Critical patent/CN106692762A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/894—Dioscoreaceae (Yam family)
    • A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/19—Acanthaceae (Acanthus family)
    • A61K36/195—Strobilanthes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233—Bupleurum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315—Isatis, e.g. Dyer's woad
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488—Pueraria (kudzu)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605—Morus (mulberry)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634—Forsythia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/78—Saururaceae (Lizard's-tail family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/79—Schisandraceae (Schisandra family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a composition for preventing and treating grass carp red skin diseases. The composition is characterized by being prepared from the following raw materials in parts by weight: 3-6 parts of dioscorea bulbifera, 10-15 parts of isatis roots, 6-10 parts of fructus forsythia, 3-5 parts of cyrtomium fortune, 5-8 parts of liquorice, 5-8 parts of houttuynia cordata, 2-5 parts of kudzu vine roots, 3-6 parts of folium mori, 6-10 parts of radix bupleuri, 5-8 parts of rhizoma phragmitis, 2-5 parts of lalang grass rhizome and 2-5 parts of schisandra chinensis. The composition has a relatively good anti-disease function, is capable of effectively preventing and treating the grass carp red skin diseases, reducing the red skin disease death rate of grass carp, and is free of toxic or side effect or medicinal residue, relatively low in production cost and convenient to use.

Description

A kind of composition for preventing and treating grass carp red skin disease
Technical field
The present invention is related to the disease treatment of the grass carp in aquaculture, and in particular to a kind of group for preventing and treating grass carp red skin disease Compound.
Background technology
Red skin disease red skin pest, wipes skin pest etc. also known as Haemorrhagic Septicaemia.Red skin disease be grass carp, black carp principal disease it One.Respectively breeded fish area in China, there is prevalence throughout the year, morbidity optimum water temperature is 25-30 DEG C；Agreed with because feeding and management is improper Fish body is damaged or body surface is because parasite parasitism most easily triggers this disease.Sick fish is slow in action, slow in reacting, it is weak, peel off solely swim in The water surface, body surface part or large-area hemorrhage inflammation, scale come off, and particularly fish body both sides and belly are the most obvious.Fin is congested, tail Portion rots, and is formed " moth fin ".Hubei Province up and down of fish and gill cover part are congested, in block erythema.In season in severe winter, fish body skin also may be used This disease can be infected because of frostbite.Red skin has turned into one of principal disease of harm pisciculture, is brought seriously to pisciculture Economic loss.It is many at this stage for grass carp red skin disease to be treated using western medicine antibiotics, although aquatic medicine control is tighter Lattice, but western medicine antibiotics abuse condition is still extremely serious, and animal body immunity degradation, medicament residue problem are made using antibiotic Also increasingly weigh, serious threat is caused to food-safety problem.
The content of the invention
It is an object of the invention to overcome shortcoming present in prior art, there is provided a kind of reasonable recipe, prepare it is simple, A kind of composition of preventing and treating grass carp red skin disease easy to use.
The composition of described a kind of preventing and treating grass carp red skin disease, it is characterised in that be made up of the raw material of following weight portion：Airpotato yam 3 ~6 parts, 10~15 parts of Radix Isatidis, 6~10 parts of the capsule of weeping forsythia, 3~5 parts of rhizome of cyrtomium, 5~8 parts of Radix Glycyrrhizae, 5~8 parts of cordate houttuynia, the root of kudzu vine 2~5 Part, 3~6 parts of mulberry leaf, 6~10 parts of radix bupleuri, 5~8 parts of reed rhizome, 2~5 parts of rhizoma imperatae, 2~5 parts of the fruit of Chinese magnoliavine.
A kind of preparation method of the composition of above-mentioned preventing and treating grass carp red skin disease is：Each original is weighed by described weight portion Material, by the sum-rate 1 of bulk drug:10 add water, and soak 60 minutes, and conventionally decoct twice, and filtering merges twice Filtrate obtains final product composition.
The application method of a kind of composition for preventing and treating grass carp red skin disease, it is characterised in that by liquid full pool spilling head, sprinkle The amount of spilling is 3~5ppm.
A kind of above-mentioned composition material effect parsing for preventing and treating grass carp red skin disease：
Airpotato yam：Heat-clearing, cool blood, detoxify, disappear goitre, with antibacterial, goiter, suppress heart, suppress intestinal smooth muscle, excitement Uterine smooth muscle, hypoglycemic etc. are acted on；
Radix Isatidis：Clearing heat and detoxicating, cool blood relieving sore-throat.Make with antibacterium, virus, antiendotoxin, anticancer, enhancing immunological regulation etc. With；
The capsule of weeping forsythia：Clearing heat and detoxicating, dispersing swelling and dissipating binds, it is antimicrobial, suppress phosphodiesterase, lipoxygenase effect, town tell, anti-liver injury, Anti-inflammatory；
Rhizome of cyrtomium：Clearing heat and detoxicating, desinsection, hemostasis；
Radix Glycyrrhizae：Anti-inflammatory, antiulcer, antianaphylaxis, anticancer, antibacterial are antiviral, promote pancreatic secretion, have suppression in vitro intestines, Regulation immunologic function；
Cordate houttuynia：The clearing heat and detoxicating, carbuncle that disappears apocenosis, inducing diuresis for treating strangurtia, there is antibacterial, antiviral, Immune-enhancing effect and diuresis；
The root of kudzu vine：Expelling pathogenic factors from muscles and skin is brought down a fever, promotes the production of body fluid, promoting eruption, Shengyang Zhixie；
Mulberry leaf：Dispelling wind and heat from the body, clearing away the lungheat and moisturizing, clear liver and improve vision, antibacterial can promote cell growth, stimulate dermal cell to divide；
Radix bupleuri：With anti-inflammatory, antipyretic, calm, analgesia, antibechic and anticonvulsant action, with antiulcer, antibacterial, antiviral, anti-swollen The effect such as fat content, Antiradiation injury in knurl, liter hyperglycaemia, reduction blood；
Reed rhizome：Clearing heat and promoting fluid, relieving restlessness, preventing or arresting vomiting, diuresis, containing vitamin B1, vitamin B2, vitamin C；
Rhizoma imperatae：Cooling blood and hemostasis, reducing fever and causing diuresis, rush blood coagulation, increase immunologic function；
The fruit of Chinese magnoliavine：Astringent or styptic treatment for spontaneous sweating, nourishing generate fluid, kidney calming are restrained, promotes body's immunity, protect liver, induced liver drug metabolism The effects such as enzyme, antitumor, cardiac stimulant, enhancing organism adaptation ability, antiulcer, anti-nephropathy, antibacterial.
Beneficial effect：
1st, energy effectively preventing grass carp red skin disease, reduces because grass carp red skin disease is dead；
2nd, using the cooperation of Chinese herbal medicine formula, it is not likely to produce the resistance to the action of a drug；
3rd, many advantages, such as lacking with safe, residual.
Specific embodiment：
Embodiment one:
The composition of described a kind of preventing and treating grass carp red skin disease, it is characterised in that be made up of the raw material of following weight portion：Airpotato yam 5 Part, 14 parts of Radix Isatidis, 6 parts of the capsule of weeping forsythia, 3 parts of rhizome of cyrtomium, 5 parts of Radix Glycyrrhizae, 7 parts of cordate houttuynia, 5 parts of the root of kudzu vine, 4 parts of mulberry leaf, 10 parts of radix bupleuri, reed rhizome 8 parts, 2 parts of rhizoma imperatae, 2 parts of the fruit of Chinese magnoliavine.
Embodiment two:
The composition of described a kind of preventing and treating grass carp red skin disease, it is characterised in that be made up of the raw material of following weight portion：Airpotato yam 4 Part, 13 parts of Radix Isatidis, 7 parts of the capsule of weeping forsythia, 4 parts of rhizome of cyrtomium, 6 parts of Radix Glycyrrhizae, 6 parts of cordate houttuynia, 4 parts of the root of kudzu vine, 5 parts of mulberry leaf, 9 parts of radix bupleuri, reed rhizome 7 Part, 3 parts of rhizoma imperatae, 3 parts of the fruit of Chinese magnoliavine.
Embodiment three:
The composition of described a kind of preventing and treating grass carp red skin disease, it is characterised in that be made up of the raw material of following weight portion：Airpotato yam 3 Part, 12 parts of Radix Isatidis, 8 parts of the capsule of weeping forsythia, 5 parts of rhizome of cyrtomium, 7 parts of Radix Glycyrrhizae, 5 parts of cordate houttuynia, 3 parts of the root of kudzu vine, 6 parts of mulberry leaf, 8 parts of radix bupleuri, reed rhizome 6 Part, 4 parts of rhizoma imperatae, 4 parts of the fruit of Chinese magnoliavine.
A kind of preparation method of the composition of preventing and treating grass carp red skin disease of examples detailed above is：Weighed respectively by described weight portion Raw material, by the sum-rate 1 of raw material:10 add water, and soak 60 minutes, and conventionally decoct twice, and filtering merges twice Filtrate obtains final product.
The composition application method of described a kind of preventing and treating grass carp red skin disease, it is characterised in that sprinkle the full pond of composition liquid Spill, the amount of splashing is 3~5ppm.
Experiment effect of the invention
The tail of red skin disease grass carp 600 is taken, is divided into four groups, point four ponds are placed, and the tail of disease fish 150 is put into per pond, and water is deep 1.5 meters, 25 DEG C or so of water temperature of control.Blank group is routinely conserved, and experimental group 1 uses embodiments of the invention one, and experimental group 2 is using the present invention Embodiment two, experimental group 3 uses embodiments of the invention three, experimental group by composition liquid full pool spilling head, once a day, The amount of splashing is 4ppm, records the 10 days data of fish such as following tables：
Blank group Experimental group 1 Experimental group 2 Experimental group 3
Sick fish number 150 150 150 150
Survival number 76 142 138 140
Survival rate 50.7% 94.7% 92.0% 93.3%
The present invention has good curative effect to grass carp red skin disease as can be seen from the above table.
The above, is only presently preferred embodiments of the present invention, is not the limitation for making other forms to the present invention, is appointed What those skilled in the art changed possibly also with the technology contents of the disclosure above or be modified as equivalent variations etc. Effect embodiment.But it is every without departing from technical solution of the present invention content, according to technical spirit of the invention to above example institute Any simple modification, equivalent variations and the remodeling made, still fall within the protection domain of technical solution of the present invention.

Claims (1)

1. it is a kind of prevent and treat grass carp red skin disease composition, it is characterised in that be made up of the raw material of following weight portion：Airpotato yam 3~6 Part, 10~15 parts of Radix Isatidis, 6~10 parts of the capsule of weeping forsythia, 3~5 parts of rhizome of cyrtomium, 5~8 parts of Radix Glycyrrhizae, 5~8 parts of cordate houttuynia, 2~5 parts of the root of kudzu vine, 3~6 parts of mulberry leaf, 6~10 parts of radix bupleuri, 5~8 parts of reed rhizome, 2~5 parts of rhizoma imperatae, 2~5 parts of the fruit of Chinese magnoliavine.
CN201710126170.8A 2017-03-06 2017-03-06 Composition for preventing and treating grass carp red skin disease Withdrawn CN106692762A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107812061A (en) * 2017-11-27 2018-03-20 衡阳市日升娃娃鱼养殖基地 A kind of natural bactericidal agent for giant salamander skin degerming and preparation method thereof
CN108142330A (en) * 2018-02-11 2018-06-12 东兰县安篓东二养殖场 The management method that Hongsuihe River grass carp is fed

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103417709A (en) * 2013-08-29 2013-12-04 天津生机集团股份有限公司 Traditional Chinese medicine granules for controlling red-skin diseases of grass carps and preparation method thereof
CN106421503A (en) * 2016-12-18 2017-02-22 长沙瑞多康生物科技有限公司 Composition for preventing and treating red skin disease of grass carps

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103417709A (en) * 2013-08-29 2013-12-04 天津生机集团股份有限公司 Traditional Chinese medicine granules for controlling red-skin diseases of grass carps and preparation method thereof
CN106421503A (en) * 2016-12-18 2017-02-22 长沙瑞多康生物科技有限公司 Composition for preventing and treating red skin disease of grass carps

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107812061A (en) * 2017-11-27 2018-03-20 衡阳市日升娃娃鱼养殖基地 A kind of natural bactericidal agent for giant salamander skin degerming and preparation method thereof
CN108142330A (en) * 2018-02-11 2018-06-12 东兰县安篓东二养殖场 The management method that Hongsuihe River grass carp is fed

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