CN106692753A - Traditional Chinese medicine composition for improving halitosis, and preparation method and application thereof - Google Patents
Traditional Chinese medicine composition for improving halitosis, and preparation method and application thereof Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/285—Aucklandia
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention discloses a traditional Chinese medicine composition for improving halitosis, and a preparation method and application thereof. Effective ingredients of the traditional Chinese medicine composition are prepared from, by weight parts, 9-15 parts of astragalus, 2-8 parts of liquorice, 3-9 parts of tangerine peel, 3-6 parts of radix aucklandiae, 3-9 parts of rhizoma corydalis, 3-9 parts of panax pseudoginseng, 9-15 parts of lalang grass rhizome and 9-15 parts of cirsium japonicum. The traditional Chinese medicine composition is reasonable in compatibility, and various medicines are used together to achieve an effect of improving halitosis caused by gastric collateral stagnation.
Description
Technical field
The present invention relates to the field of Chinese medicines, more particularly to a kind of Chinese medicine composition and preparation method for improving halitosis and
Its application.
Background technology
Halitosis refers to a kind of illness that dirty smelly smell is given out in oral cavity, shows as having obvious stink when exhaling more.Typically
Be apt to occur in the elderly, usually influence people's social interaction, have in addition cause mental handicape, especially in modern society with
The contacts of people are more frequent, therefore halitosis brings many worried and inconvenience to its work and life, and these patients are often gargling, brush
Tooth eats chewing gum and alleviates oral cavity smell, however, these are cured the symptoms, not the disease, it is difficult to reach the purpose of radical cure.
The content of the invention
Based on this, one of the object of the invention is to provide a kind of Chinese medicine composition for improving halitosis.
The concrete technical scheme for solving above-mentioned technical problem is as follows：
A kind of Chinese medicine composition for improving halitosis, the active ingredient of the Chinese medicine composition by following weight parts original
Material medicine is prepared from：Radix Astragali 9-15 parts, Radix Glycyrrhizae 2-8 parts, dried orange peel 3-9 parts, banksia rose 3-6 parts, corydalis tuber 3-9 parts, pseudo-ginseng 3-9 parts,
Rhizoma imperatae 9-15 parts, setose thistle 9-15 parts.
Preferably, the active ingredient of the Chinese medicine composition is prepared from by the bulk drug of following weight parts：Radix Astragali 10-13
Part, Radix Glycyrrhizae 3-6 parts, dried orange peel 4-8 parts, banksia rose 3-5 parts, corydalis tuber 4-8 parts, pseudo-ginseng 4-8 parts, rhizoma imperatae 10-13 parts, setose thistle 10-
13 parts.
Preferably, the active ingredient of the Chinese medicine composition is prepared from by the bulk drug of following weight parts：Radix Astragali 11-12
Part, Radix Glycyrrhizae 5-6 parts, dried orange peel 5-6 parts, banksia rose 3-4 parts, corydalis tuber 5-6 parts, pseudo-ginseng 5-6 parts, rhizoma imperatae 11-12 parts, setose thistle 11-
12 parts.
Another object of the present invention is to provide a kind of above-mentioned preparation method for improving the Chinese medicine composition of halitosis, bag
Include following steps：
1) Radix Astragali, Radix Glycyrrhizae, dried orange peel, corydalis tuber, pseudo-ginseng, rhizoma imperatae and setose thistle are first decocted；
2) banksia rose is descended afterwards, is filtered, you can.
Preferably, step 1) decoction time be 10-25min.
Preferably, step 2) banksia rose decocting time be 5-10min.
Prepared for caused by improving gastric collateral stasis another object of the present invention is to provide a kind of above-mentioned Chinese medicine composition
Halitosis medicine or health products in application.
The pharmacological property of each bulk drug of Chinese medicine composition of the present invention and effect are as follows：
The Radix Astragali：It is sweet, tepor.Return lung, the spleen channel.Tonifying Qi and lifting yang, strengthening exterior and reducing sweat, inducing diuresis for removing edema, blood-nourishing of promoting the production of body fluid, the stagnant logical numbness of row,
Detoxification apocenosis, expelling pus and promoting granulation.For treatment deficiency of vital energy weak, anorexia and loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration,
Deficiency of vital energy oedema, Heat Diabetes, blood deficiency chlorosis, hemiplegia, numbness pain is numb, ulcer is difficult to burst, burst for a long time and does not holds back.
Radix Glycyrrhizae：It is sweet, flat.The thoughts of returning home, lung, spleen, stomach.Invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain reconciles all
Medicine.For insufficiency of the spleen weakness, lassitude hypodynamia, palpitation, coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction, carbuncle sore tumefacting virus, abirritant
It is thing toxicity, strong.
Dried orange peel：It is bitter, pungent, temperature.Return lung, the spleen channel.Regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm.For abdominal fullness and distention, deficiency of food is spitted blood, cough
Abundant expectoration.
The banksia rose：Pungent, hardship, temperature.Returns spleen, stomach, large intestine, three burnt, gallbladder channels.Promoting qi circulation and relieving pain, reinforcing spleen to promote digestion.For chest side of body, gastral cavity abdomen
Distending pain, weight after rush down dysentery, dyspepsia, do not feel like eating.Roasted RADIX AUCKLANDIAE reality intestines antidiarrheal.For stomachache of having loose bowels.
Corydalis tuber (corydalis tuber)：Pungent, hardship, temperature.Return liver, the spleen channel.Promoting blood circulation, promoting the circulation of qi, analgesic.For chest side of body, epigastric pain, the obstruction of qi in the chest
It is pained, closed dysmenorrhea, postpartum stasis, tumbling and swelling.
Pseudo-ginseng：Sweet, slight bitter, temperature.Return liver, stomach.Dissipate stasis of blood hemostasis, detumescence ding-tong.For spitting blood, spit blood, bleeding from five sense organs or subcutaneous tissue is had blood in stool,
Uterine bleeding, traumatism and bleeding, chest and abdomen shouting pain, tumbling and swelling.
Rhizoma imperatae：It is sweet, tremble with fear.Return lung, stomach, bladder warp.Cooling blood and hemostasis, reducing fever and causing diuresis.Spitted blood for blood-head, bleeding from five sense organs or subcutaneous tissue, hematuria,
Pyreticosis polydipsia, jaundice with damp-heat pathogen, oedema oliguria, puckery pain of heat gonorrhea.
Setose thistle：Sweet, bitter, cold.The thoughts of returning home, Liver Channel.Cooling blood and hemostasis, dissipates stasis of blood removing toxicity for eliminating carbuncles.For bleeding from five sense organs or subcutaneous tissue, haematemesis, hematuria, just
Blood, uterine bleeding, traumatism and bleeding, carbuncle sore tumefacting virus.
A kind of Chinese medicine composition for improving halitosis of the present invention and its preparation method and application has following excellent
Point and beneficial effect：
1) rationally, all medicines share is significantly improved because of stomach network Chinese medicine composition compatibility of the present invention by promoting blood circulation and removing blood stasis
Halitosis caused by stasis blocking.
2) preparation method of the present invention, it is simple, convenient.
Specific embodiment
Below with reference to specific embodiment, the present invention will be further described, so that those skilled in the art are clearer
The solution present invention, but and it is not so limited the present invention.
Embodiment 1
The present embodiment is related to a kind of Chinese medicine composition for improving halitosis, its active ingredient by following weight bulk drug
It is prepared from：Radix Astragali 12g, Radix Glycyrrhizae 6g, dried orange peel 6g, banksia rose 3g, corydalis tuber 6g, pseudo-ginseng 6g, rhizoma imperatae 12g, setose thistle 12g.
The above-mentioned preparation method for improving the Chinese medicine composition of halitosis, step is as follows：
First take the Radix Astragali, Radix Glycyrrhizae, dried orange peel, corydalis tuber, pseudo-ginseng, rhizoma imperatae and setose thistle and decoct 10-25min, then the lower banksia rose, decoct
5-10min, filtering takes filter residue and continues to decoct, and filtering merges filtrate twice, you can.
Embodiment 2
The present embodiment is related to a kind of Chinese medicine composition for improving halitosis, its active ingredient by following weight bulk drug
It is prepared from：Radix Astragali 9g, Radix Glycyrrhizae 2g, dried orange peel 3g, banksia rose 3g, corydalis tuber 3g, pseudo-ginseng 3g, rhizoma imperatae 9g, setose thistle 9g.
The above-mentioned preparation method for improving the Chinese medicine composition of halitosis is with reference to embodiment 1.
Embodiment 3
The present embodiment is related to a kind of Chinese medicine composition for improving halitosis, its active ingredient by following weight bulk drug
It is prepared from：Radix Astragali 12g, Radix Glycyrrhizae 6g, dried orange peel 8g, banksia rose 5g, corydalis tuber 8g, pseudo-ginseng 8g, rhizoma imperatae 13g, setose thistle 12g.
The above-mentioned preparation method for improving the Chinese medicine composition of halitosis is with reference to embodiment 1.
Beneficial effects of the present invention are described further below in conjunction with model case in practice.
First, diagnostic criteria
1st, Western medicine diagnostic criteria
The Rosenberg scoring schemes recommended by the symposium of international halitosis in 1999 are divided into three degree
Slight halitosis：Slight halitosis, there is peculiar smell certainly, but very slight；
Severe halitosis：Obvious halitosis；
Severe halitosis：Serious halitosis but examiner still bears hard, notably fetor, examiner cannot stand.
2nd, tcm diagnosis standard
Gastric collateral stasis are demonstrate,proved：Primary symptom：A, gastral cavilty fixed pain, tenderness；B, dimly red tongue or purple dark, there is petechia ecchymosis.Secondary disease：
With the passing of time a, stomachache do not heal；B, black stool；C, dim complexion；D, stringy and hesitant pulse.Card type determines：Possess primary symptom 2 plus time disease 1,
Or primary symptom the 1st plus time disease 2.
2nd, exclusion standard
A, gastroscope or barium check the alimentary canal structural disease change person such as Diagnosis of Peptic Ulcer, stomach cancer thoroughly；
B, the department of stomatology check the suffering from oral disease such as periodontitis, gingivitis；
C, there is smoking history person in the recent period, in the recent period the food of feed tanginess, or the person that takes some drugses；
D, with internal organs serious disease or other systems disease, the observation that such as cirrhosis, uremia may affect the treatment
Person；
E, women's pregnancy, menstrual period, nursing period person.
3rd, inclusive criteria
It is a, all while meet traditional Chinese and western medicine diagnostic criteria, without any one person in exclusion standard；
B, age 18-60 year person；
C, the subject for voluntarily coordinating participation experiment.
4th, clinical data
According to case selection standard, Eligibility 80 is divided into treatment group 1 (20, man 8, female 12, average age
35-60 Sui, the average course of disease 5-10 months, slight halitosis 9, moderate halitosis 9, severe halitosis 2), treatment group 2 (20, man 10
Example, female 10, average age 32-57 Sui, the average course of disease 4-12 months, slight halitosis 8, moderate halitosis 11, severe halitosis 1
Example), treatment group 3 (20, man 12, female 8, average age 39-55 Sui, the average course of disease 4-10 months, slight halitosis 8, moderate
Halitosis 10, severe halitosis 2), control group (20, man 10, female 10, average age 40-55 Sui, average course of disease 3-12
Month, slight halitosis 10, moderate halitosis 9, severe halitosis 1), four groups in aspect conditions such as sex, the course of disease and lesion weights
Without significant difference, with comparativity.
5th, treatment method
Treatment group 1-3 takes the Chinese medicine composition obtained by embodiment 1-3,2 times/day respectively.Control group is taken：The Radix Astragali
12g, Radix Glycyrrhizae 6g, dried orange peel 6g, banksia rose 3g, corydalis tuber 6g, pseudo-ginseng 6g, preparation method is with reference to 1,2 times/day of embodiment.The course for the treatment of is 2
Other drugs are disabled during week, treatment, it is to avoid pungent cold and cool food.
6th, criterion of therapeutical effect
It is almost recovered：Halitosis symptom disappears；
Effectively：Halitosis symptom mitigation, degree reduction；
It is invalid：It is not improved.
7th, treatment results
Four groups of comparitive studies the results are shown in Table 1.As it can be seen from table 1 total effective rate treatment group 1>Treatment group 3>Treatment group 2>
Control group.Illustrate that the Chinese medicine composition obtained by embodiment can significantly improve the halitosis symptom caused by gastric collateral stasis.Four groups of treatments
Front and rear to have no obvious adverse reaction, blood, routine urinalysis and biochemical indicator have no abnormal changes.
Table 1
| Group | Example | Recovery from illness | Effectively | It is invalid | Total effective rate |
| Control group | 20 | 9 | 7 | 4 | 80% |
| Treatment group 1 | 20 | 14 | 5 | 1 | 95% |
| Treatment group 2 | 20 | 11 | 6 | 3 | 85% |
| Treatment group 3 | 20 | 13 | 5 | 2 | 90% |
Claims (7)
1. a kind of Chinese medicine composition for improving halitosis, it is characterised in that the active ingredient of the Chinese medicine composition is by following
The bulk drug of weight portion is prepared from：Radix Astragali 9-15 parts, Radix Glycyrrhizae 2-8 parts, dried orange peel 3-9 parts, banksia rose 3-6 parts, corydalis tuber 3-9 parts,
Pseudo-ginseng 3-9 parts, rhizoma imperatae 9-15 parts, setose thistle 9-15 parts.
2. the Chinese medicine composition for improving halitosis according to claim 1, it is characterised in that the Chinese medicine composition
Active ingredient is prepared from by the bulk drug of following weight parts：Radix Astragali 10-13 parts, Radix Glycyrrhizae 3-6 parts, dried orange peel 4-8 parts, banksia rose 3-5
Part, corydalis tuber 4-8 parts, pseudo-ginseng 4-8 parts, rhizoma imperatae 10-13 parts, setose thistle 10-13 parts.
3. the Chinese medicine composition for improving halitosis according to claim 2, it is characterised in that the Chinese medicine composition
Active ingredient is prepared from by the bulk drug of following weight parts：Radix Astragali 11-12 parts, Radix Glycyrrhizae 5-6 parts, dried orange peel 5-6 parts, banksia rose 3-4
Part, corydalis tuber 5-6 parts, pseudo-ginseng 5-6 parts, rhizoma imperatae 11-12 parts, setose thistle 11-12 parts.
4. the preparation method of a kind of Chinese medicine composition for improving halitosis as described in above-mentioned any one of claim 1-3, its
It is characterised by, comprises the following steps：
1) Radix Astragali, Radix Glycyrrhizae, dried orange peel, corydalis tuber, pseudo-ginseng, rhizoma imperatae and setose thistle are first decocted；
2) banksia rose is descended afterwards, is filtered, you can.
5. the preparation method for improving the Chinese medicine composition of halitosis according to claim 4, it is characterised in that step 1)
The time of the decoction is 10-25min.
6. the preparation method for improving the Chinese medicine composition of halitosis according to claim 4, it is characterised in that step 2)
The decocting time of the banksia rose is 5-10min.
7. it is used to improve gastric collateral stasis in preparation for improving the Chinese medicine composition of halitosis as described in claim any one of 1-3
Application in the medicine or health products of caused halitosis.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107281360A (en) * | 2017-06-12 | 2017-10-24 | 贵阳中医学院 | A kind of Chinese medicine composition, preparation and preparation method for treating halitosis |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101371901A (en) * | 2007-08-22 | 2009-02-25 | 牟培新 | Orally taken Chinese medicinal composition for treating bad breath |
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2016
- 2016-12-31 CN CN201611268835.0A patent/CN106692753A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101371901A (en) * | 2007-08-22 | 2009-02-25 | 牟培新 | Orally taken Chinese medicinal composition for treating bad breath |
Non-Patent Citations (1)
| Title |
|---|
| 迟莉丽等: "《脾胃病新治》", 31 May 2015, 中医古籍出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107281360A (en) * | 2017-06-12 | 2017-10-24 | 贵阳中医学院 | A kind of Chinese medicine composition, preparation and preparation method for treating halitosis |
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Application publication date: 20170524 |