CN106690318A - Le food health care granula and preparing method thereof - Google Patents

Le food health care granula and preparing method thereof Download PDF

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Publication number
CN106690318A
CN106690318A CN201611155520.5A CN201611155520A CN106690318A CN 106690318 A CN106690318 A CN 106690318A CN 201611155520 A CN201611155520 A CN 201611155520A CN 106690318 A CN106690318 A CN 106690318A
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CN
China
Prior art keywords
dish
health care
mesh sieves
mannitol
powder
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Pending
Application number
CN201611155520.5A
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Chinese (zh)
Inventor
李冬利
张焜
秦莹
段庆
何燕
卢宇靖
冯最新
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International Healthcare Innovation Institute (jiangmen)
Wuyi University
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International Healthcare Innovation Institute (jiangmen)
Wuyi University
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Priority to CN201611155520.5A priority Critical patent/CN106690318A/en
Publication of CN106690318A publication Critical patent/CN106690318A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/254Acanthopanax or Eleutherococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The invention relates to a Le food health care granula and a preparing method thereof, and belongs to the technical field of health care food. The Le food health care granula is prepared from, by weight, 5-10 parts of Le food and 2-9 parts of auxiliary material. The Le food health care granula is free of any toxic and side effects, suitable for people of all ages and convenient to eat and has a special fragrance of Le food, and the flavor is bitter with sweetness which is suitable for the flavor of public. The main components of the Le food health care granula are a Le food extractive and mannitol, no sugar is added, blood glucose is not increased, and cholesterol is not influenced, and thus the Le food health care granula can be suitable for diabetics to eat.

Description

Yi Zhong le dish health care granules and preparation method thereof
Technical field
The invention belongs to technical field of health care food, it is related to Yi Zhong le dish health care granules and preparation method thereof.
Background technology
Chinese herbal granules refer to that the extract of Chinese medicine is with proper auxiliary materials or dry with what part fine medicinal material powder was mixed evenly to prepare Graininess formulation.Chinese herbal granules are the conventional form of Chinese drug of a class, and with soluble, easy absorption, bioavilability is high, take The features such as facilitating.The preparation of Chinese herbal granules need to be by operations such as pre-treatment, extraction, purifying concentration, shapings.Each technique should This carry out preferably with detailed research.
Le dish, scientific name Wei Bai le (Acanthopanax trifoliatus (Linn.) Merr.), also known as E Zhang le, three leaves Slender acanthopanax, Radix Acanthopanacis Trifoliati, hardship are pierced, thorn three adds, and are Araliaceae (Araliaceae) Acanthopanax (Acanthopanax) plant, widely distributed In Central China and south, the ground such as India, Philippine, Burma, Thailand, Vietnam and Bangladesh is also distributed.Le dish is medicine food Dual purpose plant, it is from ancient times among the people just to have Cai Ji le dishes as the custom for eating vegetables and health-care medicinal raw.At present, in the market Yi le dish is The product of the health products, functional food and cosmetics of raw material is relatively fewer.And, the country is also without the particle with le dish as raw material The relevant report of agent.
The content of the invention
It is an object of the invention to provide a kind of le dish with integration of drinking and medicinal herbs as principle active component, without sugar, no Increasing can heal sugar, can diabetes patients, and easy to use, effect is significant, prepare the single le dish health care granule of letter.
Another purpose of the invention is the preparation method for providing Suo Shu le dish health care granules.
The purpose of the present invention is achieved through the following technical solutions:
Yi Zhong le dish health care granules, comprising following raw material by weight:5-10 parts, auxiliary material 2-9 parts of le dish.
Preferably, Suo Shu le dish health cares granule includes following raw material by weight:5 parts of le dish, 2 parts of auxiliary material.
Preferably, the auxiliary material is mannitol.
It is further preferred that the mannitol is graininess.
The preparation method of Suo Shu le dish health care granules, comprises the following steps:
(cleaning, drying of le dish, excessively crushing, 60 mesh sieves, get are extracted twice, merged by 1) Dao le dried vegetable powder, then with distilled water Extract solution and paste is concentrated into twice, obtains extracting cream, extraction cream is vacuum dried get and extracts powder Dao le dish, it is standby;
(2) 100 mesh sieves will be crossed after the extraction powder grinding of step (1) get Dao le dish, extract powder is obtained, after mannitol is ground 80 mesh sieves are crossed, the mannitol after extract powder and grinding is positioned in mortar in proportion, ground and mixed is uniform;
(3) ethanol of appropriate 40% is added, mixing is made softwood, uniformly and quickly crosses 18 mesh sieves and pelletized;
(4) will be positioned in air dry oven by the obtained moistening particle of step (3) and dried;
(5) dried particle is crossed into 16 mesh sieves, filters out the suitable particle of granular size, after 80 mesh sieves, removed not Meet the powdered granule of size, that is, get le dish health care granule.
Preferably, step (1) is to be extracted at 75-85 DEG C twice, each 1.5-2.5h.
Preferably, the relative density that cream is extracted described in step (1) is 1.3-1.6.
Preferably, it is to dry 25-35min at 50-55 DEG C particle to be moistened described in step (4).
《Chinese Higher plant illustrated handbook》Record " le dishes bitter, pungent, cool, with clearing heat and detoxicating, expelling wind and removing dampness, relax the muscles and stimulate the blood circulation, Relieving cough and asthma the effect of ".According to《Wanshan Mountain herbal medicine》" venting QI-blood stasis, wind-dispelling is by wet, dispersing blood stasis hemostasis and pain-relieving, heat-clearing solution to record , le dish Poison ".The present inventor by long-term research find in , le dishes containing polyphenol, flavones, diterpene, triterpene and its glycoside etc. it is medicinal into Point, free radical can be removed, play the effect such as anti-oxidant, anti-inflammatory, antibacterial, anti-aging, reducing blood lipid, hypoglycemic.Le dish has rich Rich medical value, can improve body immunity, improve blood vessel elasticity, clean blood vessel, and cholesterol can be promoted to decompose, and can prevent Influenza, upper respiratory tract infection;Another outer, the content of le dish chlorophyll is very high, can strengthen cardiac function, drops blood Fat, hypotensive is antibacterial.Granule is developed by primary raw material of le dish, can fully be protected and be deposited the original nutritional ingredient of le dish, The advantages of having peculiar flavour, health-care effect and instant concurrently again simultaneously.
Beneficial effects of the present invention:Granule whole grain prepared by the present invention is loose, bright in colour and clarity is preferable.From In mouthfeel, Ju You le dish distinctive fragrance, with sweet in taste hardship, is adapted to popular taste.Replace sucrose using mannitol, without Sugar, does not increase blood sugar, does not influence cholesterol so that diabetic can similarly take, for the patient that loses weight also not Can be absorbed in " sugar trap high " because food sucrose is excessive.
Specific embodiment
Technical scheme is described in detail with reference to specific embodiment.
Embodiment 1
Yi Zhong le chinensis particle agent, comprising following raw material by weight:5 parts of le dish, 2 parts of mannitol.
The preparation method of Shang Shu le chinensis particle agent, comprises the following steps:
(cleaning, drying of le dish, excessively crushing, 60 mesh sieves, get are extracted 2h by 1) Dao le dried vegetable powder, then with distilled water at 80 DEG C, Extract twice, merge extract solution twice and be concentrated into the paste that relative density is 1.3-1.6, obtain extracting cream, cream will be extracted It is vacuum dried get standby Dao le dish extraction powder;
(2) 100 mesh sieves will be crossed after the extraction powder grinding of step (1) get Dao le dish, extract powder is obtained, by graininess mannitol 80 mesh sieves are crossed after grinding, the mannitol after extract powder and grinding is positioned in mortar, ground and mixed is uniform;
(3) ethanol of appropriate 40% is added, mixing is made softwood, uniformly and quickly crosses 18 mesh sieves and moistening particle is obtained;
(4) obtained moistening particle is positioned in being dried in air dry oven, 30min is dried at 53 DEG C;
(5) dried particle is crossed into 16 mesh sieves, filters out the suitable particle of granular size, after 80 mesh sieves, removed not Meet the powdered granule of size, get is Dao le chinensis particle agent after.
Embodiment 2
Yi Zhong le chinensis particle agent, the raw material comprising following weight portion meter:10 parts of le dish, 9 parts of mannitol.
The preparation method of Shang Shu le chinensis particle agent, comprises the following steps:
(cleaning, drying of le dish, excessively crushing, 60 mesh sieves, get are extracted 2h by 1) Dao le dried vegetable powder, then with distilled water at 80 DEG C, Extract twice, merge extract solution twice and be concentrated into the paste that relative density is 1.3-1.6, obtain extracting cream, cream will be extracted It is vacuum dried get standby Dao le dish extraction powder;
(2) 100 mesh sieves will be crossed after the extraction powder grinding of step (1) get Dao le dish, extract powder is obtained, by graininess mannitol 80 mesh sieves are crossed after grinding, the mannitol after extract powder and grinding is positioned in mortar, ground and mixed is uniform;
(3) appropriate 40% ethanol is added, mixing is made softwood, uniformly and quickly crosses 18 mesh sieves and moistening particle is obtained;
(4) obtained moistening particle is positioned in being dried in air dry oven, 25min is dried at 55 DEG C;
(5) dried particle is crossed into 16 mesh sieves, filters out the suitable particle of granular size, after 80 mesh sieves, removed not Meet the powdered granule of size, get is Dao le chinensis particle agent after.
Embodiment 3
Yi Zhong le chinensis particle agent, the raw material comprising following weight portion meter:8 parts of le dish, 6 parts of mannitol.
The preparation method of Shang Shu le chinensis particle agent, comprises the following steps:
(cleaning, drying of le dish, excessively crushing, 60 mesh sieves, get are extracted 2h by 1) Dao le dried vegetable powder, then with distilled water at 80 DEG C, Extract twice, merge extract solution twice and be concentrated into the paste that relative density is 1.3-1.6, obtain extracting cream, cream will be extracted It is vacuum dried get standby Dao le dish extraction powder;
(2) 100 mesh sieves will be crossed after the extraction powder grinding of step (1) get Dao le dish, extract powder is obtained, by graininess mannitol 80 mesh sieves are crossed after grinding, the mannitol after extract powder and grinding is positioned in mortar, ground and mixed is uniform;
(3) ethanol of appropriate 40% is added, mixing is made softwood, uniformly and quickly crosses 18 mesh sieves and moistening particle is obtained;
(4) obtained moistening particle is positioned in being dried in air dry oven, 30min is dried at 50 DEG C;
(5) dried particle is crossed into 16 mesh sieves, filters out the suitable particle of granular size, after 80 mesh sieves, removed not Meet the powdered granule of size, get is Dao le chinensis particle agent after.

Claims (8)

1. Yi Zhong le dish health care granule, it is characterised in that comprising following raw material by weight:5-10 parts of le dish, auxiliary material 2-9 parts.
2. according to claim 1 Suo Shu le dish health care granules, it is characterised in that comprising following raw material by weight: 5 parts of le dish, 2 parts of auxiliary material.
3. according to claim 1 or 2 Shu le dish health care granules, it is characterised in that the auxiliary material is mannitol.
4. according to claim 3 Suo Shu le dish health care granules, it is characterised in that the mannitol is graininess.
5. according to the preparation method of claim 1-4 any one Suo Shu le dish health care granules, it is characterised in that including following Step:
(cleaning, drying of le dish, excessively crushing, 60 mesh sieves, get are extracted twice, merged twice by 1) Dao le dried vegetable powder, then with distilled water Extract solution is simultaneously concentrated into paste, obtains extracting cream, and extraction cream is vacuum dried into get extracts powder Dao le dish, standby;
(2) 100 mesh sieves will be crossed after the extraction powder grinding of step (1) get Dao le dish, obtains extract powder, 80 are crossed after mannitol is ground Mesh sieve, the mannitol after extract powder and grinding is positioned in mortar in proportion, and ground and mixed is uniform;
(3) 40% ethanol is added, mixing is made softwood, uniformly and quickly crosses 18 mesh sieves and pelletized;
(4) will be positioned in air dry oven by the obtained moistening particle of step (3) and dried;
(5) dried particle is crossed into 16 mesh sieves, after 80 mesh sieves, that is, get s le dish health care granule.
6. according to the preparation method of claim 5 Suo Shu le dish health care granules, it is characterised in that step (1) Zhong le dried vegetable Powder is extracted twice at 75-85 DEG C with distilled water, each 1.5-2.5h.
7. according to the preparation method of claim 5 Suo Shu le dish health care granules, it is characterised in that soaked described in step (1) The relative density for carrying cream is 1.3-1.6.
8. according to the preparation method of claim 5 Suo Shu le dish health care granules, it is characterised in that wet described in step (4) Profit particle is to dry 25-35min at 50-55 DEG C.
CN201611155520.5A 2016-12-14 2016-12-14 Le food health care granula and preparing method thereof Pending CN106690318A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101953862A (en) * 2009-07-15 2011-01-26 财团法人食品工业发展研究所 Extracts of eleutherococcus spp., preparation process thereof and use of the same
CN102919826A (en) * 2012-08-03 2013-02-13 广东工业大学 Health-care product containing acanthopanan trifoliatus extract as main active component
CN102961695A (en) * 2012-08-03 2013-03-13 广东工业大学 Acanthopanan trifoliatus (L.) Merr. health care product and preparation method thereof
CN103070880A (en) * 2013-01-30 2013-05-01 广东药学院 Application of acanthopanax trifoliatus polysaccharide in preparing medicine for treating diabetes
CN105595148A (en) * 2016-01-06 2016-05-25 广东工业大学 Acanthopanax trifoliatus effervescence solid drink and preparing method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101953862A (en) * 2009-07-15 2011-01-26 财团法人食品工业发展研究所 Extracts of eleutherococcus spp., preparation process thereof and use of the same
CN102919826A (en) * 2012-08-03 2013-02-13 广东工业大学 Health-care product containing acanthopanan trifoliatus extract as main active component
CN102961695A (en) * 2012-08-03 2013-03-13 广东工业大学 Acanthopanan trifoliatus (L.) Merr. health care product and preparation method thereof
CN103070880A (en) * 2013-01-30 2013-05-01 广东药学院 Application of acanthopanax trifoliatus polysaccharide in preparing medicine for treating diabetes
CN105595148A (en) * 2016-01-06 2016-05-25 广东工业大学 Acanthopanax trifoliatus effervescence solid drink and preparing method thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
张旭红等: "白多糖片的制备工艺研究", 《萍乡学院学报》 *
朱晓薇,等: "《中药药剂学》", 31 May 2015, 中国农业大学出版社 *
李小芳: "《生物与化学制药综合实训》", 31 July 2019, 武汉大学出版社 *

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Application publication date: 20170524