CN106668217A - Drops for treating upper respiratory infection and preparation method thereof - Google Patents
Drops for treating upper respiratory infection and preparation method thereof Download PDFInfo
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- 206010057190 Respiratory tract infections Diseases 0.000 title claims abstract description 29
- 206010046306 Upper respiratory tract infection Diseases 0.000 title claims abstract description 29
- 238000002360 preparation method Methods 0.000 title claims abstract description 12
- 208000020029 respiratory tract infectious disease Diseases 0.000 title abstract 4
- 241001082119 Cystacanthus Species 0.000 claims abstract description 19
- 241000466346 Neoalsomitra integrifoliola Species 0.000 claims abstract description 19
- 239000002994 raw material Substances 0.000 claims abstract description 12
- 239000007788 liquid Substances 0.000 claims description 41
- 239000000203 mixture Substances 0.000 claims description 30
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 28
- 238000001914 filtration Methods 0.000 claims description 28
- 239000000843 powder Substances 0.000 claims description 28
- 238000010992 reflux Methods 0.000 claims description 26
- 239000000284 extract Substances 0.000 claims description 22
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 claims description 18
- 244000235603 Acacia catechu Species 0.000 claims description 18
- 235000006226 Areca catechu Nutrition 0.000 claims description 18
- 235000003826 Artemisia Nutrition 0.000 claims description 18
- 235000003261 Artemisia vulgaris Nutrition 0.000 claims description 18
- 235000008534 Capsicum annuum var annuum Nutrition 0.000 claims description 18
- 240000008384 Capsicum annuum var. annuum Species 0.000 claims description 18
- 241000628997 Flos Species 0.000 claims description 18
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- 235000009052 artemisia Nutrition 0.000 claims description 18
- 239000010231 banlangen Substances 0.000 claims description 18
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 16
- 238000010438 heat treatment Methods 0.000 claims description 10
- 238000001035 drying Methods 0.000 claims description 7
- 238000001704 evaporation Methods 0.000 claims description 7
- 230000008020 evaporation Effects 0.000 claims description 7
- 238000000605 extraction Methods 0.000 claims description 7
- 230000001954 sterilising effect Effects 0.000 claims description 7
- 238000004659 sterilization and disinfection Methods 0.000 claims description 7
- 238000002137 ultrasound extraction Methods 0.000 claims description 7
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- 230000000694 effects Effects 0.000 abstract description 7
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- LTINPJMVDKPJJI-UHFFFAOYSA-N iodinated glycerol Chemical compound CC(I)C1OCC(CO)O1 LTINPJMVDKPJJI-UHFFFAOYSA-N 0.000 abstract 1
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
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- A—HUMAN NECESSITIES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
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- A61K2236/30—Extraction of the material
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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Abstract
The invention discloses drops for treating upper respiratory infection. The drops are prepared from the following raw materials in parts by weight: 2-5 parts of mint, 8-12 parts of fructus forsythia, 8-12 parts of honeysuckle, 6-10 parts of isatis roots, 5-8 parts of centella, 7-11 parts of Cystacanthus yunnanensis W.W.Smith, 4-7 parts of neoalsomitra integrifoliola, 5-9 parts of pteridophyta, 3-6 parts of glycyrrhiza, 11-14 parts of artemisia dracunculus.L, 7-10 parts of golden larch bark, 2-5 parts of wadalee-gum-trees, 3-6 parts of spina date seeds and 2-5 parts of eupatorium. The invention also discloses a preparation method of the drops for treating upper respiratory infection. The drops prepared by the invention are external drugs applied to an affected part, so that the drops are convenient to use and durable in efficacy and have a good treatment effect on upper respiratory infection.
Description
Technical field
The present invention relates to technical field of Chinese medicines, specifically a kind of to treat drop of upper respiratory tract infection and preparation method thereof.
Background technology
Upper respiratory tract infection is referred to from nasal cavity to the acutely inflamed general name between throat, is modal infectious disease
Disease.The sick four seasons, any age can fall ill, by being propagated containing the virulent spittle, droplet, or the apparatus of Jing pollutions.
Often when Abwehrkraft des Koepers are reduced, such as catch cold, it is tired, situations such as drench with rain, it is former existing or by the viral or/and thin of extraneous intrusion
Bacterium, mushrooms out breeding, causes infection.Chang Jifa bronchitis, pneumonia, nasal sinusitis, a few peoples can complicated with acute myocarditiss,
Nephritis, rheumatic fever etc..Upper respiratory tract infection clinical manifestation can be divided into Types Below：First, common cold.Draw for virus infection
Rise, be commonly called as " cold ".Onset is more anxious, is mainly shown as sniffle, such as sneeze, nasal obstruction, stream clear water sample nasal mucus, can also appear as
Cough, dry pharynx, itching throat or burn feeling even Postnasal drip sense.2nd, acute viral pharyngitis and laryngitis.By rhinovirus, adenoviruss,
Influenza virus, parainfluenza viruses and enteroviruses, respiratory syncytial virus etc. cause.Clinical manifestation is itching throat and burning sensation, is swallowed
Pain is not obvious.Cough is rare.Acute laryngitiss mostly are influenza virus, parainfluenza viruses and adenoviruss etc. and cause, and clinical manifestation is bright
Aobvious hoarseness, difficulty speaking, can there are heating, pharyngalgia or cough, have sore throat during cough and increase.3rd, acute herpetic angina.It is many
Caused by CA, show as obvious pharyngalgia, heating.Summer is mainly in, child is more common in, occasionally in adult.4th, it is anxious
Property pharyngo conjunctivitis.Mainly caused by adenoviruss, Coxsackie viruss etc..Heating, pharyngalgia are shown as, photophobia, shed tears, swallowed and conjunctiva is bright
Aobvious hyperemia.5th, acute pharyngoamygdalitis.Pathogen mostly is Hemolytic streptococcuss, is secondly hemophilus influenza, pneumonia streptococcus
Bacterium, staphylococcuses etc..Onset urgency, pharyngalgia is obvious, the heat that occurs together, fear of cold, and body temperature is up to more than 39 DEG C.Having a medical check-up, it is pharyngeal bright to find
Aobvious hyperemia, there is yellow purulent secretion on antiadoncus, hyperemia, surface.Sometimes with neck submental lymph nodess enlargement, tenderness, and lung
Portion haves a medical check-up absence of signs.6th, complication.Small number of patients can complicated with acute sinusitis, otitis media, tracheitis and bronchitis.To swallow
Inflammation for performance upper respiratory tract infection, some patientss can secondary the Hemolytic streptococcuss rheumatic fever, the glomerulonephritiies that cause etc., it is few
Number patients can concurrent viral myocarditis, should be vigilant.Part youngster causes sudden death due to there occurs viral myocarditis,
Significant.If upper susceptible people occurs, and chest is stuffy all should to be paid close attention to, it is impossible to adopted a casual attitude.
Mainly treated using antibiotic currently for upper respiratory tract infection, not only expensive, curative effect is general, and
There is larger side effect, life-time service antibiotic can also reduce Abwehrkraft des Koepers, cause bacterial drug resistance.Although also there is treatment
The Chinese medicine of upper respiratory tract infection, but species is various, and dragons and fishes jumbled together, and the not good defect of generally existing drug effect.
The content of the invention
It is an object of the invention to provide a kind of treat drop of upper respiratory tract infection and preparation method thereof, it is above-mentioned to solve
The problem proposed in background technology.
For achieving the above object, the present invention provides following technical scheme：
A kind of drop for treating upper respiratory tract infection, is made up of the following raw material according to percentage by weight：Herba Menthae 2-5 parts, Fructus Forsythiae
8-12 parts, Flos Lonicerae 8-12 parts, Radix Isatidis 6-10 parts, Herba Centellae 5-8 parts, Cystacanthus yunnanensis W. W. Smith 7-11 part, Neoalsomitra integrifoliola (Cogn.) Hucth. 4-7 parts, Polygonum cynanchoides Hemsl.
5-9 parts, Radix Glycyrrhizae 3-6 parts, green pepper Artemisia 11-14 parts, Cortex Pseudolariciss 7-10 parts, catechu 2-5 parts, Semen Ziziphi Spinosae 3-6 parts, Herba Eupatorii 2-5 parts.
As further scheme of the invention：It is made up of the following raw material according to percentage by weight：Herba Menthae 3-4 parts, Fructus Forsythiae
9-11 parts, Flos Lonicerae 9-11 parts, Radix Isatidis 7-9 parts, Herba Centellae 6-7 parts, Cystacanthus yunnanensis W. W. Smith 8-10 part, Neoalsomitra integrifoliola (Cogn.) Hucth. 5-6 parts, Polygonum cynanchoides Hemsl. 6-
8 parts, Radix Glycyrrhizae 4-5 parts, green pepper Artemisia 12-13 parts, Cortex Pseudolariciss 8-9 parts, catechu 3-4 parts, Semen Ziziphi Spinosae 4-5 parts, Herba Eupatorii 3-4 parts.
As further scheme of the invention：It is made up of the following raw material according to percentage by weight：3 parts of Herba Menthae, Fructus Forsythiae
10 parts, 9 parts of Flos Lonicerae, 8 parts of Radix Isatidis, 7 parts of Herba Centellae, 9 parts of Cystacanthus yunnanensis W. W. Smith, 5 parts of Neoalsomitra integrifoliola (Cogn.) Hucth., 7 parts of Polygonum cynanchoides Hemsl., 4 parts of Radix Glycyrrhizae, green pepper Artemisia
12 parts, 9 parts of Cortex Pseudolariciss, 3 parts of catechu, 5 parts of Semen Ziziphi Spinosae, 4 parts of Herba Eupatorii.
The preparation method of the drop of the treatment upper respiratory tract infection, step is as follows：
1）Polygonum cynanchoides Hemsl., Cortex Pseudolariciss are weighed, is cleaned, drying is crushed, after mix homogeneously, add the vinegar of 2-3 times of weight, soaked 5-7 days
Take out, bakee 30-40min, obtain the first powder；
2）Radix Isatidis, Neoalsomitra integrifoliola (Cogn.) Hucth., catechu and Semen Ziziphi Spinosae are weighed, is respectively washed, dries, crushed, the first powder is added after merging, mixed
After closing uniformly, the second powder is obtained；
3）The edible ethanol of 8-10 times of weight, heating and refluxing extraction 50-60min is added to filter, flowed back into the second powder
Extracting solution and backflow filtering residue, by reflux, extract, filtering residue the edible ethanol of 3-4 times of weight, ultrasonic extraction 40- are added again
50min, filters, and obtains ultrasonic extract and ultrasonic filtering residue；
4）Herba Menthae, Fructus Forsythiae, Flos Lonicerae, Herba Centellae, Cystacanthus yunnanensis W. W. Smith, Radix Glycyrrhizae, green pepper Artemisia and Herba Eupatorii are weighed, are respectively washed, dry, are crushed,
Add ultrasonic filtering residue, after mix homogeneously, obtain mixture after merging；
5）Mixture is put in container, the water of 10-15 times of weight is added, 1-2h is soaked, 1-2h is decocted, the first decoction liquor is obtained
With the first medicinal residues, the first medicinal residues are added into again the water of 6-8 times of weight, soak 1-2h, decoct 1-2h, obtain the second decoction liquor and
Second medicinal residues, the first decoction liquor and the second decoction liquor are merged, and are filtered, and are obtained and are decocted total liquid；
6）Total liquid, reflux extracting liquid and ultrasonic extract will be decocted to merge, filtered, then evaporation and concentration will be relatively close at 60 DEG C
Spend the medicinal liquid for 1.10-1.12；
7）After medicinal liquid irradiation sterilization, subpackage, you can.
Compared with prior art, the invention has the beneficial effects as follows：
Drop prepared by the present invention is external used medicine, is administered by affected part, and medication is convenient, and lasting medicine, to upper respiratory tract sense
Dye has good therapeutic effect.The present invention prepare drop be pure Chinese medicine composition, without antibiotic, will not produce dependency and
Drug resistance, and toxic and side effects are little, are more easy to by the acceptance of extensive patients.
Specific embodiment
Technical scheme is described in more detail with reference to specific embodiment.
Embodiment 1
A kind of drop for treating upper respiratory tract infection, is made up of the following raw material according to percentage by weight：2 parts of Herba Menthae, Fructus Forsythiae 8
Part, 8 parts of Flos Lonicerae, 6 parts of Radix Isatidis, 5 parts of Herba Centellae, 7 parts of Cystacanthus yunnanensis W. W. Smith, 4 parts of Neoalsomitra integrifoliola (Cogn.) Hucth., 5 parts of Polygonum cynanchoides Hemsl., 3 parts of Radix Glycyrrhizae, green pepper Artemisia 11
Part, 7 parts of Cortex Pseudolariciss, 2 parts of catechu, 3 parts of Semen Ziziphi Spinosae, 2 parts of Herba Eupatorii.
In the present embodiment, the preparation method of the drop of the treatment upper respiratory tract infection, step is as follows：
1）Polygonum cynanchoides Hemsl., Cortex Pseudolariciss are weighed, is cleaned, drying is crushed, after mix homogeneously, add the vinegar of 2 times of weight, immersion to take for 5 days
Go out, bakee 30min, obtain the first powder；
2）Radix Isatidis, Neoalsomitra integrifoliola (Cogn.) Hucth., catechu and Semen Ziziphi Spinosae are weighed, is respectively washed, dries, crushed, the first powder is added after merging, mixed
After closing uniformly, the second powder is obtained；
3）Add the edible ethanol of 8 times of weight, heating and refluxing extraction 50min to filter into the second powder, obtain reflux extracting liquid
With backflow filtering residue, the edible ethanol of 3 times of weight, ultrasonic extraction 40min is added to filter, obtain again reflux, extract, filtering residue
Ultrasonic extract and ultrasonic filtering residue；
4）Herba Menthae, Fructus Forsythiae, Flos Lonicerae, Herba Centellae, Cystacanthus yunnanensis W. W. Smith, Radix Glycyrrhizae, green pepper Artemisia and Herba Eupatorii are weighed, are respectively washed, dry, are crushed,
Add ultrasonic filtering residue, after mix homogeneously, obtain mixture after merging；
5）Mixture is put in container, the water of 10 times of weight is added, 1h is soaked, 1h is decocted, the first decoction liquor and first is obtained
First medicinal residues are added again the water of 6 times of weight by medicinal residues, soak 1h, decoct 1h, obtain the second decoction liquor and the second medicinal residues, will
First decoction liquor and the second decoction liquor merge, and filter, and obtain and decoct total liquid；
6）Total liquid, reflux extracting liquid and ultrasonic extract will be decocted to merge, filtered, then evaporation and concentration will be relatively close at 60 DEG C
Spend the medicinal liquid for 1.10；
7）After medicinal liquid irradiation sterilization, subpackage, you can.
Embodiment 2
A kind of drop for treating upper respiratory tract infection, is made up of the following raw material according to percentage by weight：3 parts of Herba Menthae, Fructus Forsythiae 9
Part, 11 parts of Flos Lonicerae, 9 parts of Radix Isatidis, 6 parts of Herba Centellae, 8 parts of Cystacanthus yunnanensis W. W. Smith, 5 parts of Neoalsomitra integrifoliola (Cogn.) Hucth., 8 parts of Polygonum cynanchoides Hemsl., 5 parts of Radix Glycyrrhizae, green pepper Artemisia
13 parts, 8 parts of Cortex Pseudolariciss, 3 parts of catechu, 5 parts of Semen Ziziphi Spinosae, 4 parts of Herba Eupatorii.
In the present embodiment, the preparation method of the drop of the treatment upper respiratory tract infection, step is as follows：
1）Polygonum cynanchoides Hemsl., Cortex Pseudolariciss are weighed, is cleaned, drying is crushed, after mix homogeneously, add the vinegar of 2 times of weight, immersion to take for 6 days
Go out, bakee 32min, obtain the first powder；
2）Radix Isatidis, Neoalsomitra integrifoliola (Cogn.) Hucth., catechu and Semen Ziziphi Spinosae are weighed, is respectively washed, dries, crushed, the first powder is added after merging, mixed
After closing uniformly, the second powder is obtained；
3）Add the edible ethanol of 8 times of weight, heating and refluxing extraction 53min to filter into the second powder, obtain reflux extracting liquid
With backflow filtering residue, the edible ethanol of 3 times of weight, ultrasonic extraction 45min is added to filter, obtain again reflux, extract, filtering residue
Ultrasonic extract and ultrasonic filtering residue；
4）Herba Menthae, Fructus Forsythiae, Flos Lonicerae, Herba Centellae, Cystacanthus yunnanensis W. W. Smith, Radix Glycyrrhizae, green pepper Artemisia and Herba Eupatorii are weighed, are respectively washed, dry, are crushed,
Add ultrasonic filtering residue, after mix homogeneously, obtain mixture after merging；
5）Mixture is put in container, the water of 12 times of weight is added, 1.5h is soaked, 2h is decocted, the first decoction liquor and the is obtained
First medicinal residues are added again the water of 6 times of weight by one medicinal residues, soak 2h, decoct 1.5h, obtain the second decoction liquor and the second medicine
Slag, the first decoction liquor and the second decoction liquor are merged, and are filtered, and are obtained and are decocted total liquid；
6）Total liquid, reflux extracting liquid and ultrasonic extract will be decocted to merge, filtered, then evaporation and concentration will be relatively close at 60 DEG C
Spend the medicinal liquid for 1.11；
7）After medicinal liquid irradiation sterilization, subpackage, you can.
Embodiment 3
A kind of drop for treating upper respiratory tract infection, is made up of the following raw material according to percentage by weight：3 parts of Herba Menthae, Fructus Forsythiae 10
Part, 9 parts of Flos Lonicerae, 8 parts of Radix Isatidis, 7 parts of Herba Centellae, 9 parts of Cystacanthus yunnanensis W. W. Smith, 5 parts of Neoalsomitra integrifoliola (Cogn.) Hucth., 7 parts of Polygonum cynanchoides Hemsl., 4 parts of Radix Glycyrrhizae, green pepper Artemisia 12
Part, 9 parts of Cortex Pseudolariciss, 3 parts of catechu, 5 parts of Semen Ziziphi Spinosae, 4 parts of Herba Eupatorii.
In the present embodiment, the preparation method of the drop of the treatment upper respiratory tract infection, step is as follows：
1）Polygonum cynanchoides Hemsl., Cortex Pseudolariciss are weighed, is cleaned, drying is crushed, after mix homogeneously, add the vinegar of 3 times of weight, immersion to take for 7 days
Go out, bakee 35min, obtain the first powder；
2）Radix Isatidis, Neoalsomitra integrifoliola (Cogn.) Hucth., catechu and Semen Ziziphi Spinosae are weighed, is respectively washed, dries, crushed, the first powder is added after merging, mixed
After closing uniformly, the second powder is obtained；
3）Add the edible ethanol of 9 times of weight, heating and refluxing extraction 55min to filter into the second powder, obtain reflux extracting liquid
With backflow filtering residue, the edible ethanol of 4 times of weight, ultrasonic extraction 45min is added to filter, obtain again reflux, extract, filtering residue
Ultrasonic extract and ultrasonic filtering residue；
4）Herba Menthae, Fructus Forsythiae, Flos Lonicerae, Herba Centellae, Cystacanthus yunnanensis W. W. Smith, Radix Glycyrrhizae, green pepper Artemisia and Herba Eupatorii are weighed, are respectively washed, dry, are crushed,
Add ultrasonic filtering residue, after mix homogeneously, obtain mixture after merging；
5）Mixture is put in container, add 13 times of weight water, soak 1.5h, decoct 1.5h, obtain the first decoction liquor and
First medicinal residues are added again the water of 7 times of weight by the first medicinal residues, soak 1.5h, decoct 1.5h, obtain the second decoction liquor and second
Medicinal residues, the first decoction liquor and the second decoction liquor are merged, and are filtered, and are obtained and are decocted total liquid；
6）Total liquid, reflux extracting liquid and ultrasonic extract will be decocted to merge, filtered, then evaporation and concentration will be relatively close at 60 DEG C
Spend the medicinal liquid for 1.11；
7）After medicinal liquid irradiation sterilization, subpackage, you can.
Embodiment 4
A kind of drop for treating upper respiratory tract infection, is made up of the following raw material according to percentage by weight：4 parts of Herba Menthae, Fructus Forsythiae 11
Part, 9 parts of Flos Lonicerae, 7 parts of Radix Isatidis, 7 parts of Herba Centellae, 10 parts of Cystacanthus yunnanensis W. W. Smith, 6 parts of Neoalsomitra integrifoliola (Cogn.) Hucth., 6 parts of Polygonum cynanchoides Hemsl., 4 parts of Radix Glycyrrhizae, green pepper Artemisia
12 parts, 9 parts of Cortex Pseudolariciss, 4 parts of catechu, 4 parts of Semen Ziziphi Spinosae, 3 parts of Herba Eupatorii.
In the present embodiment, the preparation method of the drop of the treatment upper respiratory tract infection, step is as follows：
1）Polygonum cynanchoides Hemsl., Cortex Pseudolariciss are weighed, is cleaned, drying is crushed, after mix homogeneously, add the vinegar of 3 times of weight, immersion to take for 6 days
Go out, bakee 38min, obtain the first powder；
2）Radix Isatidis, Neoalsomitra integrifoliola (Cogn.) Hucth., catechu and Semen Ziziphi Spinosae are weighed, is respectively washed, dries, crushed, the first powder is added after merging, mixed
After closing uniformly, the second powder is obtained；
3）Add the edible ethanol of 9 times of weight, heating and refluxing extraction 57min to filter into the second powder, obtain reflux extracting liquid
With backflow filtering residue, the edible ethanol of 4 times of weight, ultrasonic extraction 45min is added to filter, obtain again reflux, extract, filtering residue
Ultrasonic extract and ultrasonic filtering residue；
4）Herba Menthae, Fructus Forsythiae, Flos Lonicerae, Herba Centellae, Cystacanthus yunnanensis W. W. Smith, Radix Glycyrrhizae, green pepper Artemisia and Herba Eupatorii are weighed, are respectively washed, dry, are crushed,
Add ultrasonic filtering residue, after mix homogeneously, obtain mixture after merging；
5）Mixture is put in container, the water of 14 times of weight is added, 2h is soaked, 1.5h is decocted, the first decoction liquor and the is obtained
First medicinal residues are added again the water of 7 times of weight by one medicinal residues, soak 2h, decoct 1.5h, obtain the second decoction liquor and the second medicine
Slag, the first decoction liquor and the second decoction liquor are merged, and are filtered, and are obtained and are decocted total liquid；
6）Total liquid, reflux extracting liquid and ultrasonic extract will be decocted to merge, filtered, then evaporation and concentration will be relatively close at 60 DEG C
Spend the medicinal liquid for 1.12；
7）After medicinal liquid irradiation sterilization, subpackage, you can.
Embodiment 5
A kind of drop for treating upper respiratory tract infection, is made up of the following raw material according to percentage by weight：5 parts of Herba Menthae, Fructus Forsythiae 12
Part, 12 parts of Flos Lonicerae, 10 parts of Radix Isatidis, 8 parts of Herba Centellae, 11 parts of Cystacanthus yunnanensis W. W. Smith, 7 parts of Neoalsomitra integrifoliola (Cogn.) Hucth., 9 parts of Polygonum cynanchoides Hemsl., 6 parts of Radix Glycyrrhizae, green pepper
14 parts of Artemisia, 10 parts of Cortex Pseudolariciss, 5 parts of catechu, 6 parts of Semen Ziziphi Spinosae, 5 parts of Herba Eupatorii.
In the present embodiment, the preparation method of the drop of the treatment upper respiratory tract infection, step is as follows：
1）Polygonum cynanchoides Hemsl., Cortex Pseudolariciss are weighed, is cleaned, drying is crushed, after mix homogeneously, add the vinegar of 3 times of weight, immersion to take for 7 days
Go out, bakee 40min, obtain the first powder；
2）Radix Isatidis, Neoalsomitra integrifoliola (Cogn.) Hucth., catechu and Semen Ziziphi Spinosae are weighed, is respectively washed, dries, crushed, the first powder is added after merging, mixed
After closing uniformly, the second powder is obtained；
3）Add the edible ethanol of 10 times of weight, heating and refluxing extraction 60min to filter into the second powder, obtain reflux, extract,
Liquid and backflow filtering residue, add again the edible ethanol of 4 times of weight, ultrasonic extraction 50min to filter, obtain reflux, extract, filtering residue
Obtain ultrasonic extract and ultrasonic filtering residue；
4）Herba Menthae, Fructus Forsythiae, Flos Lonicerae, Herba Centellae, Cystacanthus yunnanensis W. W. Smith, Radix Glycyrrhizae, green pepper Artemisia and Herba Eupatorii are weighed, are respectively washed, dry, are crushed,
Add ultrasonic filtering residue, after mix homogeneously, obtain mixture after merging；
5）Mixture is put in container, the water of 15 times of weight is added, 2h is soaked, 2h is decocted, the first decoction liquor and first is obtained
First medicinal residues are added again the water of 8 times of weight by medicinal residues, soak 2h, decoct 2h, obtain the second decoction liquor and the second medicinal residues, will
First decoction liquor and the second decoction liquor merge, and filter, and obtain and decoct total liquid；
6）Total liquid, reflux extracting liquid and ultrasonic extract will be decocted to merge, filtered, then evaporation and concentration will be relatively close at 60 DEG C
Spend the medicinal liquid for 1.12；
7）After medicinal liquid irradiation sterilization, subpackage, you can.
The using method of drop prepared by the present invention is：Twice a day, using front, patient first drinks appropriate warm water, so
Drop is instilled in mouth afterwards.
Through clinical trial, dropping liquid prepared by the present invention has reached 96% to the effective percentage of upper respiratory tract infection, and takes effect
Hurry up, medication can take effect for latter to two days.
Drop prepared by the present invention is external used medicine, is administered by affected part, and medication is convenient, and lasting medicine, to upper breathing
Road infection has good therapeutic effect.Drop prepared by the present invention is pure Chinese medicine composition, without antibiotic, will not produce dependence
Property and drug resistance, and toxic and side effects are little, are more easy to by the acceptance of extensive patients.
The better embodiment of the present invention is explained in detail above, but the present invention is not limited to above-mentioned embodiment party
Formula, in the ken that one skilled in the relevant art possesses, can be with the premise of without departing from present inventive concept
Various changes can be made.
Claims (4)
1. a kind of drop for treating upper respiratory tract infection, is characterised by, is made up of the following raw material according to percentage by weight：Herba Menthae
2-5 parts, Fructus Forsythiae 8-12 parts, Flos Lonicerae 8-12 parts, Radix Isatidis 6-10 parts, Herba Centellae 5-8 parts, Cystacanthus yunnanensis W. W. Smith 7-11 part, Neoalsomitra integrifoliola (Cogn.) Hucth. 4-7
Part, Polygonum cynanchoides Hemsl. 5-9 parts, Radix Glycyrrhizae 3-6 parts, green pepper Artemisia 11-14 parts, Cortex Pseudolariciss 7-10 parts, catechu 2-5 parts, Semen Ziziphi Spinosae 3-6 parts, Herba Eupatorii
2-5 parts.
2. it is according to claim 1 treatment upper respiratory tract infection drop, it is characterised in that by following according to weight percent
The raw material of ratio is made：Herba Menthae 3-4 parts, Fructus Forsythiae 9-11 parts, Flos Lonicerae 9-11 parts, Radix Isatidis 7-9 parts, Herba Centellae 6-7 parts, Cystacanthus yunnanensis W. W. Smith
8-10 parts, Neoalsomitra integrifoliola (Cogn.) Hucth. 5-6 parts, Polygonum cynanchoides Hemsl. 6-8 parts, Radix Glycyrrhizae 4-5 parts, green pepper Artemisia 12-13 parts, Cortex Pseudolariciss 8-9 parts, catechu 3-4 parts, acid
Semen Ziziphi Spinosae 4-5 parts, Herba Eupatorii 3-4 parts.
3. it is according to claim 2 treatment upper respiratory tract infection drop, it is characterised in that by following according to weight percent
The raw material of ratio is made：3 parts of Herba Menthae, 10 parts of Fructus Forsythiae, 9 parts of Flos Lonicerae, 8 parts of Radix Isatidis, 7 parts of Herba Centellae, 9 parts of Cystacanthus yunnanensis W. W. Smith, Neoalsomitra integrifoliola (Cogn.) Hucth. 5
Part, 7 parts of Polygonum cynanchoides Hemsl., 4 parts of Radix Glycyrrhizae, 12 parts of green pepper Artemisia, 9 parts of Cortex Pseudolariciss, 3 parts of catechu, 5 parts of Semen Ziziphi Spinosae, 4 parts of Herba Eupatorii.
4. a kind of preparation method of the drop of the treatment upper respiratory tract infection as described in claim 1-3 is arbitrary, it is characterised in that
Step is as follows：
1）Polygonum cynanchoides Hemsl., Cortex Pseudolariciss are weighed, is cleaned, drying is crushed, after mix homogeneously, add the vinegar of 2-3 times of weight, soaked 5-7 days
Take out, bakee 30-40min, obtain the first powder；
2）Radix Isatidis, Neoalsomitra integrifoliola (Cogn.) Hucth., catechu and Semen Ziziphi Spinosae are weighed, is respectively washed, dries, crushed, the first powder is added after merging, mixed
After closing uniformly, the second powder is obtained；
3）The edible ethanol of 8-10 times of weight, heating and refluxing extraction 50-60min is added to filter, flowed back into the second powder
Extracting solution and backflow filtering residue, by reflux, extract, filtering residue the edible ethanol of 3-4 times of weight, ultrasonic extraction 40- are added again
50min, filters, and obtains ultrasonic extract and ultrasonic filtering residue；
4）Herba Menthae, Fructus Forsythiae, Flos Lonicerae, Herba Centellae, Cystacanthus yunnanensis W. W. Smith, Radix Glycyrrhizae, green pepper Artemisia and Herba Eupatorii are weighed, are respectively washed, dry, are crushed,
Add ultrasonic filtering residue, after mix homogeneously, obtain mixture after merging；
5）Mixture is put in container, the water of 10-15 times of weight is added, 1-2h is soaked, 1-2h is decocted, the first decoction liquor is obtained
With the first medicinal residues, the first medicinal residues are added into again the water of 6-8 times of weight, soak 1-2h, decoct 1-2h, obtain the second decoction liquor and
Second medicinal residues, the first decoction liquor and the second decoction liquor are merged, and are filtered, and are obtained and are decocted total liquid；
6）Total liquid, reflux extracting liquid and ultrasonic extract will be decocted to merge, filtered, then evaporation and concentration will be relatively close at 60 DEG C
Spend the medicinal liquid for 1.10-1.12；
7）After medicinal liquid irradiation sterilization, subpackage, you can.
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| CN107184845A (en) * | 2017-06-12 | 2017-09-22 | 肖厥明 | It is a kind of to treat pediatric nasal medicine of the infection of the upper respiratory tract and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107184845A (en) * | 2017-06-12 | 2017-09-22 | 肖厥明 | It is a kind of to treat pediatric nasal medicine of the infection of the upper respiratory tract and preparation method thereof |
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