CN106659150B - 用于维护被收获的待移植心脏的设备 - Google Patents

用于维护被收获的待移植心脏的设备 Download PDF

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Publication number
CN106659150B
CN106659150B CN201580022610.4A CN201580022610A CN106659150B CN 106659150 B CN106659150 B CN 106659150B CN 201580022610 A CN201580022610 A CN 201580022610A CN 106659150 B CN106659150 B CN 106659150B
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China
Prior art keywords
heart
module
pump
perfusate
portable system
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Chinese (zh)
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CN106659150A (zh
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D·弗里德
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Transmedics Inc
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Tevosol Inc
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Priority to CN202110540466.0A priority Critical patent/CN113229273B/zh
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/14—Mechanical aspects of preservation; Apparatus or containers therefor
    • A01N1/142—Apparatus
    • A01N1/143—Apparatus for organ perfusion
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/14—Mechanical aspects of preservation; Apparatus or containers therefor
    • A01N1/142—Apparatus
    • A01N1/144—Apparatus for temperature control, e.g. refrigerators or freeze-drying apparatus
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/14—Mechanical aspects of preservation; Apparatus or containers therefor
    • A01N1/146—Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving
    • A01N1/148—Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving with provisions specially adapted for transporting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/3621—Heart stimulators for treating or preventing abnormally high heart rate
    • A61N1/3622—Heart stimulators for treating or preventing abnormally high heart rate comprising two or more electrodes co-operating with different heart regions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/3625—External stimulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/38—Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
    • A61N1/39—Heart defibrillators
    • A61N1/3968—Constructional arrangements, e.g. casings

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • External Artificial Organs (AREA)
  • Thermal Sciences (AREA)
  • Agricultural Machines (AREA)
CN201580022610.4A 2014-03-26 2015-03-18 用于维护被收获的待移植心脏的设备 Active CN106659150B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110540466.0A CN113229273B (zh) 2014-03-26 2015-03-18 用于维护被收获的待移植心脏的设备

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461970532P 2014-03-26 2014-03-26
US61/970,532 2014-03-26
PCT/CA2015/050201 WO2015143552A1 (en) 2014-03-26 2015-03-18 Apparatus for maintenance of harvested hearts for transplanting

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202110540466.0A Division CN113229273B (zh) 2014-03-26 2015-03-18 用于维护被收获的待移植心脏的设备

Publications (2)

Publication Number Publication Date
CN106659150A CN106659150A (zh) 2017-05-10
CN106659150B true CN106659150B (zh) 2021-06-01

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CN201580022610.4A Active CN106659150B (zh) 2014-03-26 2015-03-18 用于维护被收获的待移植心脏的设备
CN202110540466.0A Active CN113229273B (zh) 2014-03-26 2015-03-18 用于维护被收获的待移植心脏的设备

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Country Link
US (2) US10327442B2 (https=)
EP (3) EP4023066B1 (https=)
CN (2) CN106659150B (https=)
AU (1) AU2015234580B2 (https=)
BR (1) BR112016021971B1 (https=)
CA (2) CA3164819A1 (https=)
DK (1) DK4023066T3 (https=)
ES (2) ES3036002T3 (https=)
WO (1) WO2015143552A1 (https=)

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CN103931605B (zh) 2004-10-07 2015-11-18 特兰斯迈迪茨公司 用于活体外器官护理的系统和方法
US12010987B2 (en) 2004-10-07 2024-06-18 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US9078428B2 (en) 2005-06-28 2015-07-14 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
US9457179B2 (en) 2007-03-20 2016-10-04 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
US8420380B2 (en) 2008-01-31 2013-04-16 Transmedics, Inc. Systems and methods for ex vivo lung care
US20130011823A1 (en) 2011-04-14 2013-01-10 Hassanein Waleed H Organ care solution for ex-vivo machine perfusion of donor lungs
EP4091446A1 (en) 2012-01-17 2022-11-23 Tevosol, Inc. Apparatus for testing, assessment, and maintenance of harvested hearts for transplanting
ES3036002T3 (en) 2014-03-26 2025-09-11 Transmedics Inc Apparatus for maintenance of harvested hearts for transplanting
JP2017518301A (ja) 2014-06-02 2017-07-06 トランスメディクス， インク．Ｔｒａｎｓｍｅｄｉｃｓ， Ｉｎｃ． ｅｘ−ｖｉｖｏでの臓器管理システム
CA3155169A1 (en) 2014-12-12 2016-06-16 Tevosol, Inc. Apparatus and method for organ perfusion
CA2997267A1 (en) 2015-09-09 2017-03-16 Transmedics, Inc. Aortic cannula for ex vivo organ care system
ES2968062T3 (es) 2016-05-30 2024-05-07 Transmedics Inc Aparato y método de ventilación pulmonar ex vivo con presión exterior variable
DE102016117901A1 (de) * 2016-09-22 2018-03-22 Technische Universität Dresden System und Verfahren zur extrakorporalen Perfusion von Organen
US20200120924A1 (en) * 2017-04-21 2020-04-23 University Health Network Method and system for ex-vivo heart perfusion
KR102764137B1 (ko) * 2019-09-11 2025-02-06 현대자동차주식회사 자율주행 차량용 제세동 시스템
EP4252536A1 (en) * 2022-04-01 2023-10-04 Medizinische Hochschule Hannover Perfusion system

Citations (3)

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US5217860A (en) * 1991-07-08 1993-06-08 The American National Red Cross Method for preserving organs for transplantation by vitrification
US6046046A (en) * 1997-09-23 2000-04-04 Hassanein; Waleed H. Compositions, methods and devices for maintaining an organ
CN101072500A (zh) * 2004-10-07 2007-11-14 特兰斯迈迪茨公司 用于活体外器官护理的系统和方法

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Publication number Priority date Publication date Assignee Title
US5217860A (en) * 1991-07-08 1993-06-08 The American National Red Cross Method for preserving organs for transplantation by vitrification
US6046046A (en) * 1997-09-23 2000-04-04 Hassanein; Waleed H. Compositions, methods and devices for maintaining an organ
CN101072500A (zh) * 2004-10-07 2007-11-14 特兰斯迈迪茨公司 用于活体外器官护理的系统和方法

Also Published As

Publication number Publication date
EP3122180B1 (en) 2022-05-11
BR112016021971A2 (https=) 2017-08-15
DK4023066T3 (da) 2025-08-04
EP4023066A1 (en) 2022-07-06
CA3164819A1 (en) 2015-10-01
CN113229273B (zh) 2023-01-31
CN113229273A (zh) 2021-08-10
US20190387736A1 (en) 2019-12-26
CA2943633C (en) 2023-06-20
AU2015234580B2 (en) 2018-11-15
US20170223950A1 (en) 2017-08-10
EP3122180A1 (en) 2017-02-01
ES3036002T3 (en) 2025-09-11
EP4023066B1 (en) 2025-06-25
EP4596032A2 (en) 2025-08-06
AU2015234580A1 (en) 2016-10-27
CN106659150A (zh) 2017-05-10
ES2916212T3 (es) 2022-06-29
EP3122180A4 (en) 2018-01-03
CA2943633A1 (en) 2015-10-01
WO2015143552A1 (en) 2015-10-01
BR112016021971B1 (pt) 2022-05-17
US10327442B2 (en) 2019-06-25
EP4596032A3 (en) 2025-11-26

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Effective date of registration: 20190625

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