CN106634853A - Novel antipyretic gel - Google Patents
Novel antipyretic gel Download PDFInfo
- Publication number
- CN106634853A CN106634853A CN201611152357.7A CN201611152357A CN106634853A CN 106634853 A CN106634853 A CN 106634853A CN 201611152357 A CN201611152357 A CN 201611152357A CN 106634853 A CN106634853 A CN 106634853A
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- CN
- China
- Prior art keywords
- gel
- water
- ethyl
- borneol
- menthol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K5/00—Heat-transfer, heat-exchange or heat-storage materials, e.g. refrigerants; Materials for the production of heat or cold by chemical reactions other than by combustion
- C09K5/02—Materials undergoing a change of physical state when used
- C09K5/04—Materials undergoing a change of physical state when used the change of state being from liquid to vapour or vice versa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F2007/0203—Cataplasms, poultices or compresses, characterised by their contents; Bags therefor
- A61F2007/0215—Cataplasms, poultices or compresses, characterised by their contents; Bags therefor containing liquids other than water
- A61F2007/0219—Gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Thermal Sciences (AREA)
- Medicinal Chemistry (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Combustion & Propulsion (AREA)
- Materials Engineering (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses a novel antipyretic gel. The novel antipyretic gel is in a gelatinous state formed by mixing raw materials of carbomer, propylene glycol, ammonium hydroxide, ethyl p-hydroxybenzoate, menthol, borneol, ethyl alcohol and water at a mixing ratio of 32.9-3.1 g: 180-220 ml: 6-10 ml: 0.3-0.5 g: 0.1-0.12 g: 0.1-0.12 g: 45-55 ml: 1000-1400 ml. The novel antipyretic gel has the advantages of being significant in effects of treatment on fever, especially on children's fever, and simple, rapid, safe, reliable and painless in application.
Description
Technical field
The technical field the present invention relates to physics is brought down a fever, more particularly to a kind of fever abatement gel.
Background technology
It is well known that the reason for causing fever is a lot, especially children fever treatment gets up even more to bother, because of children's torso
Physiogeny not fully, before the reason for causing fever is not found, it is impossible to which use drug for abating fever simply is treated, this
Sample easily covers the state of an illness, affects further treatment.Therefore, what current less than 38.5 DEG C of fever was advocated is using Physical temperature-lowering side
Formula is brought down a fever.
The conventional physics of prior art brings down a fever product for defervescence plaster used, the product Main Function be affixed on forehead,
Temple and Dazhui acupoint, using the mechanism that heat is taken away during water vapor, carry out auxiliary and bring down a fever to local cooling, relax with refrigerant
Suitable, easy to use, health, it is safe the characteristics of.But it is defervescence plaster used to use a lot, not only it is pasted not strongly, it is easily de-
Fall, and often paste it is defervescence plaster used be only capable of using once, action time is short, and the gel water lock amount of patch surface is limited, actual cooling effect
And less.
The content of the invention
The technical problem to be solved is, there is provided a kind of fever abatement gel, antipyretic gel treatment heating
(especially fever in children) is evident in efficacy, and uses simple and efficient, safe and reliable, no pain.
In order to solve above-mentioned technical problem, the present invention proposes a kind of fever abatement gel, and the antipyretic gel is by including
Carbomer, propane diols, ammoniacal liquor, ethyl-para-hydroxybenzoate, menthol, borneol, second alcohol and water raw material stirring mix it is solidifying
Glue, the proportion relation between above-mentioned each raw material is：
Carbomer: propane diols: ammoniacal liquor: ethyl-para-hydroxybenzoate: menthol: borneol: ethanol: water :=2.9-3.1g: 180-
220ml∶6-10ml∶0.3-0.5g∶0.1-0.12g∶0.1-0.12g∶45-55ml∶1000-1400ml。
Preferably, the antipyretic gel by include Carbomer, propane diols, ammoniacal liquor, ethyl-para-hydroxybenzoate, menthol,
Borneol, the raw material stirring of second alcohol and water mix gel, and the proportion relation between above-mentioned each raw material is：Carbomer: the third two
Alcohol: ammoniacal liquor: ethyl-para-hydroxybenzoate: menthol: borneol: ethanol: water :=3g: 200ml: 8ml: 0.4g: 0.1-
0.12g ∶ 0.1-0.12g ∶ 50ml ∶ 1200ml。
Preferably, the antipyretic gel by include Carbomer, propane diols, ammoniacal liquor, ethyl-para-hydroxybenzoate, menthol,
Borneol, the raw material stirring of 95% second alcohol and water mix gel, and the proportion relation between above-mentioned each raw material is：Card ripple
Nurse: propane diols: ammoniacal liquor: ethyl-para-hydroxybenzoate: menthol: borneol: 95% ethanol: water :=3g: 200ml: 8ml
∶ 0.4g ∶ 0.1g ∶ 0.1g ∶ 50ml ∶ 1200ml。
Preferably, the antipyretic gel by include Carbomer, propane diols, ammoniacal liquor, ethyl-para-hydroxybenzoate, menthol,
Borneol, the raw material stirring of second alcohol and water mix gel, and the proportion relation between above-mentioned each raw material is：Carbomer: the third two
Alcohol: ammoniacal liquor: ethyl-para-hydroxybenzoate: menthol: borneol: ethanol: water :=3g: 200ml: 8ml: 0.4g:
0.12g ∶ 0.12g ∶ 50ml ∶ 1200ml.Wherein, the water is deionized water or distilled water.
Implement the present invention, have the advantages that：
The embodiment of the present invention by by Carbomer, propane diols, ammoniacal liquor, ethyl-para-hydroxybenzoate, menthol, borneol, ethanol and
The raw materials such as water stirring mixing gel makes antipyretic gel, so as to reach (especially children's antipyretic) treatment of significantly bringing down a fever
Effect, and use simple and efficient, safe and reliable, no pain.
Specific embodiment
The antipyretic gel of the present invention mainly adopts Carbomer, propane diols, ammoniacal liquor, ethyl-para-hydroxybenzoate, menthol, ice
The raw materials such as piece, second alcohol and water stirring mixing gel.Proportion relation between above-mentioned each raw material is：Carbomer: propane diols: ammonia
Water: ethyl-para-hydroxybenzoate: menthol: borneol: ethanol: water :=2.9-3.1g: 180-220ml: 6-10ml: 0.3-0.5g:
0.1-0.12g∶0.1-0.12g∶45-55ml∶1000-1400ml。
Used as a kind of more preferably embodiment, the present embodiment can be by including Carbomer, propane diols, ammoniacal liquor, para hydroxybenzene
Ethyl formate, menthol, borneol, the raw material stirring of second alcohol and water mix gel, and the proportioning between above-mentioned each raw material is closed
It is to be：Carbomer: propane diols: ammoniacal liquor: ethyl-para-hydroxybenzoate: menthol: borneol: ethanol: water :=3g: 200ml:
8ml ∶ 0.4g ∶ 0.1-0.12g ∶ 0.1-0.12g ∶ 50ml ∶ 1200ml。
Carbomer has excellent thickening property, gelation, cohesive, emulsibility, suspension and film forming, used as sustained release material
Material, carrier matrix；Ammoniacal liquor has hygroscopicity, used as emulsifying agent；Ethyl hydroxy benzoate is used as bacteriostatic agent；Organic solvent propane diols has
There is moisture-keeping function, make lubrication of feeling nice and cool after antipyretic gel external application；Ethanol is good organic solvent, and is made with stronger infiltration
With, menthol, borneol are dissolved in ethanol, can strengthen bring down a fever, cooling effect.
Two embodiments of the present invention are described below in detail.
Embodiment 1：
Antipyretic gel, mainly by Carbomer, propane diols, ammoniacal liquor, ethyl-para-hydroxybenzoate, menthol, borneol, 95% ethanol and
Water raw material stirring mixing gel.Wherein, each raw material proportioning is：
Carbomer: propane diols: ammoniacal liquor: ethyl-para-hydroxybenzoate: menthol: borneol: 95% ethanol: water :=3g:
200ml ∶ 8ml ∶ 0.4g ∶ 0.1g ∶ 0.1g ∶ 50ml ∶ 1200ml。
When implementing, water is deionized water or distilled water.
Embodiment 2：
Antipyretic gel, it is mainly former by Carbomer, propane diols, ammoniacal liquor, ethyl-para-hydroxybenzoate, menthol, borneol, second alcohol and water
Material stirring mixing gel.Wherein, each raw material proportioning is：Carbomer: propane diols: ammoniacal liquor: ethyl-para-hydroxybenzoate: peppermint
Brain: borneol: ethanol: water :=3g: 200ml: 8ml: 0.4g: 0.12g: 0.12g: 50ml: 1200ml.
When implementing, water is deionized water or distilled water.
The present invention is local topical, when using, the antipyretic gel of the present invention can be applied directly to into forehead, the sun
The skin surface at the positions such as cave, Dazhui acupoint, armpit, popliteal nests, thigh and medial leg, the principle of radiating of being volatilized using gel is right
Local cooling brings down a fever carrying out auxiliary；Compared with existing defervescence plaster used technology, the present invention is fever abatement liniment, is brought down a fever effectively
Rate
High, cooling-down effect is notable.
Or, as a kind of manner of packing of the present invention, after antipyretic gel makes, can also be dispensed into and smear ballpoint bottle
It is interior, every bottle of 30-70g.Using front opening bottle cap, Plastic ball is placed in into forehead, temple or Dazhui acupoint etc. skin surface
Return and smear, each position can smear 3 to 4 times repeatedly, be to accelerate cooling rate, can simultaneously be applied in armpit, popliteal nests, big
The position such as leg and medial leg.
The above is the preferred embodiment of the present invention, it is noted that for those skilled in the art
For, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications are also considered as
Protection scope of the present invention.
Claims (5)
1. a kind of fever abatement gel, it is characterised in that the antipyretic gel by include Carbomer, propane diols, ammoniacal liquor, to hydroxyl
Ethyl benzoate, menthol, borneol, the raw material stirring of second alcohol and water mix gel, the proportioning between above-mentioned each raw material
Relation is：Carbomer: propane diols: ammoniacal liquor: ethyl-para-hydroxybenzoate: menthol: borneol: ethanol: water :=
2.9-3.1g∶180-220ml∶6-10ml∶0.3-0.5g∶0.1-0.12g∶0.1-0.12g∶45-55ml∶1000-
1400ml。
2. the antipyretic gel as described in claim 1, it is characterised in that the antipyretic gel by include Carbomer, propane diols,
Ammoniacal liquor, ethyl-para-hydroxybenzoate, menthol, borneol, the raw material stirring of second alcohol and water mix gel, above-mentioned each raw material
Between proportion relation be：Carbomer: propane diols: ammoniacal liquor: ethyl-para-hydroxybenzoate: menthol: borneol: ethanol: water :=3g
∶200ml ∶ 8ml ∶ 0.4g ∶ 0.1-0.12g ∶ 0.1-0.12g ∶ 50ml ∶ 1200ml。
3. the antipyretic gel as described in claim 2, it is characterised in that the antipyretic gel by include Carbomer, propane diols,
Ammoniacal liquor, ethyl-para-hydroxybenzoate, menthol, borneol, the raw material stirring of 95% second alcohol and water mix gel, above-mentioned each
Proportion relation between raw material is：Carbomer: propane diols: ammoniacal liquor: ethyl-para-hydroxybenzoate: menthol: borneol: 95% second
Alcohol: water :=3g: 200ml: 8ml: 0.4g: 0.1g: 0.1g: 50ml: 1200ml.
4. thermal gels as described in claim 2, it is characterised in that the antipyretic gel is by including Carbomer, propane diols, ammonia
Water, ethyl-para-hydroxybenzoate, menthol, borneol, the raw material stirring of second alcohol and water mix gel, above-mentioned each raw material it
Between proportion relation be：Carbomer: propane diols: ammoniacal liquor: ethyl-para-hydroxybenzoate: menthol: borneol: ethanol: water :=3g:
200ml ∶ 8ml ∶ 0.4g ∶ 0.12g ∶ 0.12g ∶ 50ml ∶ 1200ml。
5. the antipyretic gel as any one of claim 1-4, it is characterised in that the water is deionized water or distillation
Water.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611152357.7A CN106634853A (en) | 2016-12-14 | 2016-12-14 | Novel antipyretic gel |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611152357.7A CN106634853A (en) | 2016-12-14 | 2016-12-14 | Novel antipyretic gel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106634853A true CN106634853A (en) | 2017-05-10 |
Family
ID=58822508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611152357.7A Pending CN106634853A (en) | 2016-12-14 | 2016-12-14 | Novel antipyretic gel |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106634853A (en) |
-
2016
- 2016-12-14 CN CN201611152357.7A patent/CN106634853A/en active Pending
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| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170510 |