CN106620657A - Healthcare agent for pet joints and preparation method thereof - Google Patents
Healthcare agent for pet joints and preparation method thereof Download PDFInfo
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- CN106620657A CN106620657A CN201510733742.XA CN201510733742A CN106620657A CN 106620657 A CN106620657 A CN 106620657A CN 201510733742 A CN201510733742 A CN 201510733742A CN 106620657 A CN106620657 A CN 106620657A
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Abstract
The invention discloses a healthcare agent for pet joints and belongs to the technical field of feed additives. The healthcare agent uses chondroitin sulfate, glucosamine hydrochloride, dimethyl sulfone and collagen as the core components and vitamins and mineral elements as the auxiliary materials and is applicable to pets with arthritis, caused by excessively fast growth and development or maldevelopment, movement damage, senile joint degeneration and the like, of different degrees. The healthcare agent can promote bone health, increase pet immunity, improve pet bone joint diseases and increase pet living quality.
Description
Technical field
Present invention relates particularly to a kind of pet joint health-care agent and preparation method thereof, belongs to field of feed additive technology.
Background technology
Osteoarthritis is a kind of degeneration bone and joint diseases of dog, is also a kind of relatively common multiple disease of dog.In fact,
Due to raising improper (limitation of activity, lack illumination etc.), or the reason such as injury gained in sports, osteoarthritis can occur all
The dog of all ages and classes, different cultivars, and all joints are likely to generation.Almost half case occurs in large-scale kind of dog,
Such as Germany hangquan, Luo Weina, many and gold sleuth is drawn, but also often sent out in more small-sized Shetland Sheepdog etc..Greatly
Quantity research shows, chondroitin sulfate compounded amino glucosamine salt hydrochlorate has good curative effect for improving osteoarthritis.
For a long time, for the arthritic treatment of pet dog cat bone, people use always aspirin, non-steroidal antalgesic etc.
Pet is helped to palliate the agonizing sufferings, but this means can not effectively treatment disease.And these medicine Long-Time Services, some effects
Fruit is gradually reduced, and some meetings produce the side effects animal healths such as gasteremphraxis.The relief from osteoarthritis disease such as Injection of Hyaluronic Acid
The factor can also have a good curative effect, but high cost, inconvenient pet owner operation, consumer is less.Gucosamine and
Chondroitin is the important component for treating osteoarthritis, and the tablet with gucosamine and chondroitin as main component is also current
The most popular product for the treatment of of arthritis.Only it is only capable of playing a part of to alleviate inflammation containing the medicine of the two.On in prior art
The treatment that composition is served only for person joint's inflammation disease is stated, it is sensitive to peculiar smell because its sense of taste, smell are flourishing for pet,
Food refusal and vomiting occurs, the performance for not entering and affecting drug effect is fed.
The content of the invention
The present invention promotes the quick restorative angle of bone to set out from inflammation is alleviated, and in addition to gucosamine and chondroitin, matches somebody with somebody
The nutriments such as trace element, vitamin, collagen, the plant extracts needed for promote the fast quick-recovery of bone, while
Addition flavouring agent, improves the palatability of product.
It is an object of the invention to provide a kind of pet joint health-care agent and preparation method thereof, the additive with chondroitin sulfate,
Aminoglucose hydrochloride, dimethyl sulfone, collagen are nucleus, are aided with vitamin and mineral element, it is adaptable to raw
It is long to develop the different degrees of arthritic pet that too fast or bad, injury gained in sports, senile articular degeneration etc. are caused.
The pet joint health-care agent includes following component:Chondroitin sulfate, aminoglucose hydrochloride, dimethyl sulfone, glue
Former albumen, vitamin D3, vitamin E, zinc gluconate, manganese gluconate, calcium gluconae, yucca extract, wind
Taste agent, auxiliary material;The flavouring agent is chicken liver meal or powdered beef.The auxiliary material is starch and lactose, and weight ratio is starch:Breast
Sugar is 4:1.
The pet joint health-care agent each component parts by weight are:Chondroitin sulfate 80-110 parts, aminoglucose hydrochloride
100-130 parts, dimethyl sulfone 2-40 parts, collagen 2-40 parts, vitamin D34-10 parts, vitamin E 8-20 parts,
Zinc gluconate 4-30 parts, manganese gluconate 4-20 parts, calcium gluconae 4-20 parts, yucca extract 15-30 parts, local flavor
Agent 30-60 parts, clout is auxiliary material 490-747 parts.
The pet joint health-care agent each component parts by weight are preferably:100 parts of chondroitin sulfate, aminoglucose hydrochloride
125 parts, 15 parts of dimethyl sulfone, 15 parts of collagen, vitamin D38 parts, 16 parts of vitamin E, zinc gluconate 20
Part, 15 parts of manganese gluconate, 8 parts of calcium gluconae, 20 parts of yucca extract, 50 parts of chicken liver meal, 608 parts of (its of auxiliary material
485 parts of middle starch, 123 parts of lactose), the joint care agent is applied to pet dog or cat, and the arthritis of dog or cat is risen
Improve adjustment effect.
The preparation method of the pet joint health-care agent is:
(1) 80-100 mesh sieves are crossed after is crushed each component in prescription respectively;
(2) by weight proportioning weighs whole chondroitin sulfates, aminoglucose hydrochloride and 3%~8% starch,
These three materials are made into gelatinized corn starch with suitable quantity of water (10g starch is watered 60ml), remaining material are weighed by weight,
The mixture that 3 times 80 mesh sieves are uniformly mixed is crossed, gelatinized corn starch is poured into said mixture, pelletize 16 after stirring
Mesh sieve is pelletized;
(3) gained particle drying, 14 mesh sieve whole grains are obtained final product.
The temperature of the drying is 50-60 DEG C, and the time of the drying is 0.5-1h.
The using method of the arthritis health-care agent is to mix with pet food, mixes food feeding, and consumption is dog class:Small-sized dog is
Once a day, 0.5g is taken every time;Medium-sized dog is each 1-1.5g once a day;Large-scale dog is each 1.5-2g once a day;
Huge dog is each 2-3g once a day;Cat class:Young cat is each 0.5g once a day;Small-sized cat for once a day,
Each 1-1.5g;Medium-sized cat is each 1.5-2g once a day;Large-scale cat is each 2-3g once a day.
Arthritis health-care agent of the present invention, can as needed make the confession such as pulvis, tablet, capsule, solution, supensoid agent
Animal edible.
The invention has the beneficial effects as follows:
Glucosamine in prescription of the present invention is a kind of important as precursors of biosynthesis cartilaginous tissue, and aminoglucose is lacked in vivo
Sugar can directly result in the generation of various bone and joint diseases;Grape candy amine is the natural materials extracting from halobios crust,
After taking as nutritional agents with reference to chondroitin, " medicine " that can become most effective and have no side effect;Simple Glucosamine and
The medicine of chondroitin combination is merely capable of playing a part of to alleviate inflammation, and the present invention is also aided with Animal Bone in addition to inflammation is alleviated
The nutriments such as trace element, vitamin, collagen and plant extracts needed for bone healthy growth, promote animal skeleton
Fast quick-recovery, while increase flavouring agent (chicken liver meal, powdered beef), so as to improve the palatability of product.
Each component in pet care agent of the present invention has following effect:
Glucosamine be constitute articular cartilage matrix in most important monose, occur osteoarthritis when, its biosynthesis block or
Deficiency, causes cartilage matrix to soften and follows the string, and knuckle synovia is reduced, cartilage wear and destruction, therefore, Glucosamine
Generation and the non-evident effect of osteoarthritis can be fundamentally blocked, and chondroitin sulfate have osteogenic action, can also be by
Joint fluid sucks cartilage so as to protect cartilage, and Glucosamine and chondroitin sulfate are shared has association well to Bones and joints protection
Same-action, it is reported that, both proportionings are 5:Action effect is optimal when 4.
It is damaged along with osteoarticular different degrees of when occurring in view of osteoarthritis, it is of the invention while inflammation is alleviated,
Supplement impaired Bones and joints and recover the nutriments such as normal required various trace elements and vitamin, collagen is articular cartilage
Main constituents, dimethyl sulfone can supply the organic sulfur for making the fast quick-recovery of tissue, rationally addition collagen and diformazan
Base sulfone helps lend some impetus to the fast quick-recovery of impaired Bones and joints.Yucca extract does not only have the effect of easing pain and diminishing inflammation, can also adjust
Gut flora health.The addition of flavouring agent can improve the palatability of product, and the basic formulation of product is granule, than piece
Agent, lozenge are more conducive to feeding animals.
Foreign countries have been related to the health-care agent of chondroitin sulfate, Glucosamine, dimethyl sulfone and collagen combination, and four all
Play the role of to treat relief from osteoarthritis, combining also has the effect of mutual collaboration, and vitamin and mineral element are mutually assisted
With bone health is promoted, immunity of pets is improved, worked along both lines, improve pet bone and joint diseases, therefore above-mentioned prescription to control
Treat the active drug and health-care agent of osteoarthritis.
Specific embodiment
The specific embodiment of the present invention is elaborated with reference to embodiments, but the invention is not limited in this, it is all
Any modification made within the spirit and principles in the present invention, equivalent and improvement etc. should be included in the protection of the present invention
In the range of.
Experimental technique described in following embodiments, if no special instructions, is conventional method;The reagent and material, such as without
Specified otherwise, commercially obtains.
Embodiment 1
The preparation of pet joint health-care agent:Each material is crushed after (smashing fineness is 80-100 mesh), according to following ratio
Take each component:Chondroitin sulfate 80g, aminoglucose hydrochloride 100g, dimethyl sulfone 2g, collagen 2g, vitamin
D34g, vitamin E 8g, zinc gluconate 4g, manganese gluconate 4g, calcium gluconae 4g, yucca extract 15g,
Chicken liver meal 30g, auxiliary material 747g (wherein starch 597g, lactose 150g).
(1) various composition in prescription is crossed respectively 80 mesh sieves;By weight proportioning weighs whole chondroitin sulfates, amino
These three materials are made gelatinized corn starch by the starch of glucosamine salt hydrochlorate and 30g with 180ml water, and residue is weighed by weight
Material, cross the mixture that 3 times 80 mesh sieves are uniformly mixed, paste is poured into said mixture, 16 after stirring
Mesh sieve is pelletized;50-60 DEG C of drying of gained particle, 14 mesh sieve whole grains are obtained final product.
(2) dog for having 30 body weight to be 8-25 kilogram, by body weight two groups, wherein the 18 of 8-15 kilogram, 15-25 kilogram are divided into
12, one group of feeding this product is test group, the piece of the existing chondroitin sulfate in one group of feeding market and Glucosamine combination
Agent is control group, and once, 8-15 kilogram of dog feeds every time 1-1.5g, and 15-25 kilogram of dog feeds every time for this product feeding daily
1.5-2g, market product is used by its operation instructions.Take and show stiff after front dog class activity, not active movement, joint portion
Position obvious tumefaction, dog hurt like hell after touch has standing and difficulty in walking.After taking this prescription, dog all has difference in 10 days
Being obviously improved for degree, somewhat increases afterwards consumption, and above-mentioned symptom is all alleviated substantially after 20 days;Control group takes market product
Afterwards first quarter moon just have it is different degrees of be obviously improved, consumption is somewhat increased afterwards, above-mentioned symptom is all alleviated substantially after one and a half months.
Embodiment 2
The preparation of pet joint health-care agent:Each material is crushed after (smashing fineness is 80-100 mesh), according to as follows
Ratio takes each component:Chondroitin sulfate 100g, aminoglucose hydrochloride 125g, dimethyl sulfone 15g, collagen 15g,
Vitamin D38g, vitamin E 16g, zinc gluconate 20g, manganese gluconate 15g, calcium gluconae 8g, yucca carries
Take thing 20g, chicken liver meal 50g, auxiliary material 608g (wherein starch 485g, lactose 123g).
(1) various composition in prescription is crossed respectively 80 mesh sieves;By weight proportioning weighs whole chondroitin sulfates, amino
These three materials are made gelatinized corn starch by glucosamine salt hydrochlorate and 30g starch with 180ml water, are weighed by weight remaining
Material, the mixture that 3 times 80 mesh sieves of mistake are uniformly mixed, gelatinized corn starch is poured into said mixture, 16 after stirring
Mesh sieve is pelletized;50-60 DEG C of drying of gained particle, 14 mesh sieve whole grains are obtained final product.
(2) there is cat after the kan setsu waza that 25 body weight are 1-5 kilogram, wherein body weight is 1-2 kilogram of young cat totally 6, and body weight is
2-3 kilogram of small-sized cat totally 5, body weight is 3-4 kilogram of medium-sized cat totally 8, and body weight is 4-5 kilogram of large-scale cat totally 6
Only, it is divided into two groups by body weight, it is test group that one group is taken this product, 1 young cat of daily feeding takes every time 0.5g;Small-sized cat
Each 1-1.5g;The each 1.5-2g of medium-sized cat;The each 2-3g of large-scale cat., one group is taken the existing chondroitin sulfate in market and amino
The tablet of glucose combination is control group, and using method is used by its operation instructions.Take front cat class activity to reduce, repose
Lazy move, local arthrocele is licked and licks arthrocele position repeatedly.After taking, cat all has different degrees of in test group 6-7 days
It is obviously improved, cat can freely walk, freely, enlargement position is obviously improved for activity, control group at least needs 10 talentes can be with
Reach the effect of test group.
Embodiment 3
The preparation of pet joint health-care agent:Each material is crushed after (smashing fineness is 80-100 mesh), according to as follows
Ratio takes each component:Chondroitin sulfate 110g, aminoglucose hydrochloride 130g, dimethyl sulfone 40g, collagen 40g,
Vitamin D310g, vitamin E 20g, zinc gluconate 30g, manganese gluconate 20g, calcium gluconae 20g, yucca carries
Thing 30g, powdered beef 60g are taken, clout is auxiliary material 490g (wherein starch 390g, lactose 100g).
(1) various composition in prescription is crossed respectively 80 mesh sieves;By weight proportioning weighs whole chondroitin sulfates, amino
These three materials are made gelatinized corn starch by the starch of glucosamine salt hydrochlorate and 30g with 180ml water, and residue is weighed by weight
Material, cross the mixture that 3 times 80 mesh sieves are uniformly mixed, gelatinized corn starch is poured into said mixture, after stirring
16 mesh sieves are pelletized;50-60 DEG C of drying of gained particle, 14 mesh sieve whole grains are obtained final product.
(2) pet care agent obtained in, feeds the arthrodyasplasia dog that 20 body weight are for 9-15 kilogram, daily to feed once,
Each 1.5-2g, it is difficult to take front dog class sitting and lying, after not liking motion this prescription, all have within 6-7 days it is different degrees of be obviously improved,
Consumption is somewhat increased afterwards, and above-mentioned symptom is all alleviated substantially after 12-14 days.Using effect has no clear superiority than embodiment 2.
The above, the only present invention preferably specific embodiment, but protection scope of the present invention is not limited thereto, and appoints
What those familiar with the art technology according to the present invention scheme and its sends out in the technical scope of present disclosure
Bright design in addition equivalent or change, all should be included within the scope of the present invention.
Claims (9)
1. a kind of pet joint health-care agent, with chondroitin sulfate, aminoglucose hydrochloride, dimethyl sulfone, collagen as core
Composition, it is characterised in that be aided with vitamin, mineral element, flavouring agent, for too fast or bad, injury gained in sports of growing,
The different degrees of arthritic pet that senile articular degeneration etc. is caused.
2. a kind of pet joint health-care agent as claimed in claim 1, is characterized in that the pet joint health-care agent includes following component:
Chondroitin sulfate, aminoglucose hydrochloride, dimethyl sulfone, collagen, vitamin D3, vitamin E, gluconic acid
Zinc, manganese gluconate, calcium gluconae, yucca extract, flavouring agent, auxiliary material.
3. a kind of pet joint health-care agent as claimed in claim 2, is characterized in that the flavouring agent in chicken liver meal, powdered beef
One kind, the auxiliary material is starch and lactose, and the weight ratio of the two is starch:Lactose is 4:1..
4. the pet joint health-care agent as described in claim 1 or 2 or 3 is arbitrary, is characterized in that, the pet joint health-care agent is each
Composition weight number is:Chondroitin sulfate 80-110 parts, aminoglucose hydrochloride 100-130 parts, dimethyl sulfone 2-40 parts,
Collagen 2-40 parts, vitamin D34-10 parts, vitamin E 8-20 parts, zinc gluconate 4-30 parts, manganese gluconate
4-20 parts, calcium gluconae 4-20 parts, yucca extract 15-30 parts, flavouring agent 30-60 parts, clout is auxiliary material 490-747
Part.
5. a kind of pet joint health-care agent as claimed in claim 4, is characterized in that each component parts by weight are:Chondroitin sulfate
100 parts of element, 125 parts of aminoglucose hydrochloride, 15 parts of dimethyl sulfone, 15 parts of collagen, vitamin D38 parts,
16 parts of vitamin E, 20 parts of zinc gluconate, 15 parts of manganese gluconate, 8 parts of calcium gluconae, yucca extract 20
Part, 50 parts of chicken liver meal, 608 parts of auxiliary material (wherein 485 parts of starch, 123 parts of lactose).
6. a kind of pet joint inflammation health-care agent, its preparation method is:
(1) 80-100 mesh sieves are crossed after is crushed each component in prescription respectively;
(2) by weight proportioning weighs whole chondroitin sulfates, aminoglucose hydrochloride and 3%~8% starch,
These three materials are made into gelatinized corn starch with suitable quantity of water (10g starch is watered 60ml), remaining material are weighed by weight,
The mixture that 3 times 80 mesh sieves are uniformly mixed is crossed, gelatinized corn starch is poured into said mixture, pelletize 16 after stirring
Mesh sieve is pelletized;
(3) gained particle drying, 14 mesh sieve whole grains are obtained final product.
7. preparation method as claimed in claim 6, the temperature that the step (3) is dried is 50-60 DEG C, the time of the drying
For 0.5-1h.
8. a kind of pet joint health-care agent as described in claim 1 to 7 is arbitrary, the using method of the health-care agent is and pet food
Product mix, and mix food feeding, and consumption is dog class:Small-sized dog is once a day, 0.5g to be taken every time;Medium-sized dog for once a day,
Each 1-1.5g;Large-scale dog is each 1.5-2g once a day;Huge dog is each 2-3g once a day;Cat class:Young cat
For once a day, each 0.5g;Small-sized cat is each 1-1.5g once a day;Medium-sized cat is each 1.5-2g once a day;
Large-scale cat is each 2-3g once a day.
9. a kind of pet joint health-care agent as claimed in claim 1, is characterized in that, the arthritis health-care agent, can make pulvis,
Tablet, capsule, solution, supensoid agent etc. supply animal edible.
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Cited By (10)
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CN107625788A (en) * | 2017-10-10 | 2018-01-26 | 北京市营养源研究所 | A kind of chick sternal cartilage and preparation method and application |
CN107952066A (en) * | 2017-11-20 | 2018-04-24 | 江苏雅博动物健康科技有限责任公司 | A kind of pet liquid calcium and preparation method thereof |
CN108450652A (en) * | 2018-02-07 | 2018-08-28 | 上海宠幸宠物用品有限公司 | A kind of health food and preparation method thereof for repairing pet dog joint injury |
CN109965104A (en) * | 2019-03-29 | 2019-07-05 | 华熙生物科技股份有限公司 | A kind of composition and its preparation method and application containing Sodium Hyaluronate |
CN110537635A (en) * | 2019-10-10 | 2019-12-06 | 北京赫亚美特生物科技有限公司 | Multifunctional pet food and preparation method thereof |
CN111956664A (en) * | 2019-12-03 | 2020-11-20 | 云南汉盟制药有限公司 | Composition for pets and application thereof |
CN113797310A (en) * | 2020-06-15 | 2021-12-17 | 中农极润生物科技(北京)有限公司 | Pet joint health-care preparation and preparation method and application thereof |
CN113796456A (en) * | 2020-06-15 | 2021-12-17 | 中农宠物营养研究院(江苏)有限公司 | Pet joint nutritional preparation and preparation method and application thereof |
CN114794313A (en) * | 2022-05-23 | 2022-07-29 | 南京联智医药科技有限公司 | Pet joint health care soft chewable tablet and preparation method thereof |
CN115553396A (en) * | 2022-10-11 | 2023-01-03 | 浙江惠嘉生物科技股份有限公司 | Functional pet food for improving joint diseases of pets and preparation method thereof |
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Cited By (11)
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CN107625788A (en) * | 2017-10-10 | 2018-01-26 | 北京市营养源研究所 | A kind of chick sternal cartilage and preparation method and application |
CN107952066A (en) * | 2017-11-20 | 2018-04-24 | 江苏雅博动物健康科技有限责任公司 | A kind of pet liquid calcium and preparation method thereof |
CN108450652A (en) * | 2018-02-07 | 2018-08-28 | 上海宠幸宠物用品有限公司 | A kind of health food and preparation method thereof for repairing pet dog joint injury |
CN109965104A (en) * | 2019-03-29 | 2019-07-05 | 华熙生物科技股份有限公司 | A kind of composition and its preparation method and application containing Sodium Hyaluronate |
CN110537635A (en) * | 2019-10-10 | 2019-12-06 | 北京赫亚美特生物科技有限公司 | Multifunctional pet food and preparation method thereof |
CN111956664A (en) * | 2019-12-03 | 2020-11-20 | 云南汉盟制药有限公司 | Composition for pets and application thereof |
CN113797310A (en) * | 2020-06-15 | 2021-12-17 | 中农极润生物科技(北京)有限公司 | Pet joint health-care preparation and preparation method and application thereof |
CN113796456A (en) * | 2020-06-15 | 2021-12-17 | 中农宠物营养研究院(江苏)有限公司 | Pet joint nutritional preparation and preparation method and application thereof |
CN113797310B (en) * | 2020-06-15 | 2024-04-12 | 中农极润生物科技(北京)有限公司 | Pet joint health care preparation and preparation method and application thereof |
CN114794313A (en) * | 2022-05-23 | 2022-07-29 | 南京联智医药科技有限公司 | Pet joint health care soft chewable tablet and preparation method thereof |
CN115553396A (en) * | 2022-10-11 | 2023-01-03 | 浙江惠嘉生物科技股份有限公司 | Functional pet food for improving joint diseases of pets and preparation method thereof |
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Application publication date: 20170510 |