CN106620101A - Gynecological pill and preparation method thereof - Google Patents

Gynecological pill and preparation method thereof Download PDF

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Publication number
CN106620101A
CN106620101A CN201611024209.7A CN201611024209A CN106620101A CN 106620101 A CN106620101 A CN 106620101A CN 201611024209 A CN201611024209 A CN 201611024209A CN 106620101 A CN106620101 A CN 106620101A
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ball
pill
pellet
gynaecology
gynecological
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魏聆
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Shaanxi Tiansen Biological Engineering Technology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234Cnidium (snowparsley)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • A61K36/515Gentiana
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/889Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
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  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention discloses a gynecological pill and a preparation method thereof. The gynecological pill is prepared from radix sophorae flavescentis, cortex phellodendri chinensis, rhizoma coptidis, fructus cnidii, fructus forsythiae, herba taraxaci, radix gentianae, catechu, olibanum, myrrha, borneol and sangusis draconis. Formula bulk drugs are porphyrized and disintegrated, and are mixed; afterwards, an appropriate amount of purified water is added into an obtained first mixture; an obtained second mixture is sufficiently mixed and is made into a soft material; a 14-mesh sieve is selected and used for granulation; granules are dried; the granules which are uniform in size are selected and taken, and are put into a coating pan; afterwards, the coating pan is rotated; a small amount of water is sprayed into the coating pan; a small amount of medicinal powder is added into the coating pan; coated pills in required size are made once through repeated operation; subsequently, the coated pills are subjected to low-temperature drying and are selected, so as to obtain the pills. A formula comprising pure natural traditional Chinese medicinal materials is adopted for the gynecological pill; the gynecological pill has the functions of clearing away heat and toxic material, eliminating dampness, killing parasites to relieve itching, activating blood circulation, easing pain, stopping bleeding and promoting tissue regeneration. Further, the dosage form of the gynecological pill is simple; the gynecological pill is enveloped by using absorbent cotton gauze, is convenient to use, and can be used for effectively treating various gynecological inflammations. The preparation method is simple in process, has a low requirement on a device, is environmentally friendly, and is suitable for industrialized enlarged production.

Description

A kind of gynaecology's pellet ball and preparation method thereof
Technical field
The present invention relates to Chinese medicine pellet ball, more particularly to a kind of gynaecology's pellet ball and preparation method thereof.
Background technology
Gynaecological imflammation is broadly divided into the inflammation of external genital organs and the inflammation of internal genitalia, is mainly shown as vaginitis, uterine neck Inflammation, pelvic infecton, adnexitis, cervical erosion, fibroid, tumour, polyp, the proliferation of mammary gland, metrauxe, endometritis, son Endometrium hyperplasia, mullerianosis, it is infertile etc. that female gynecological inflammation causes.Meeting in the case that gynaecological imflammation is serious Have influence on the mental health of women.Gynaecological imflammation mostly occurs with married femle, it is difficult to cure.
At present, Amino-Cerv common on the market is often gynecological suppository and gynaecologic washing lotion, and its main component is with antibiotic residence Many, toxic and side effect is larger, therefore considers drug effect, toxic and side effect, needs a kind of less ball of side effect of natural pure Chinese medicine badly Agent.
The content of the invention
It is an object of the invention to provide a kind of gynaecology pellet ball and preparation method thereof, gynaecology's pellet ball is matched somebody with somebody using natural traditional Chinese medicine Side, and formulation is simple, it is easy to use, can the various gynaecological imflammations of effectively treatment.
To reach above-mentioned purpose, technical scheme below is present invention employs:
A kind of gynaecology's pellet ball, the red ball includes following bulk drug:100~500g kuh-sengs, 50~200g golden cypresses, 50~200g The coptis, 50~200g frutus cnidiis, 50~200g capsules of weeping forsythia, 50~200g dandelions, 50~200g rough gentian, 50~200g catechu, 10 ~100g frankincenses, 10~100g myrrhs, 10~100g borneols and 10~100g dragon's blood.
Preferably, the red ball includes following bulk drug:100~200g kuh-sengs, 50~150g golden cypresses, 50~150g are yellow Company, 50~150g frutus cnidiis, 50~150g capsules of weeping forsythia, 50~150g dandelions, 50~150g rough gentian, 50~150g catechu, 10~ 50g frankincenses, 10~50g myrrhs, 10~50g borneols and 10~50g dragon's blood.
Preferably, the red ball includes following bulk drug:200g kuh-sengs, 120g golden cypresses, the 120g coptiss, 120 frutus cnidiis, The 90g capsules of weeping forsythia, 90g dandelions, 80g rough gentian, 100g catechu, 20g frankincenses, 20g myrrhs, 20g borneols and 20g dragon's blood.
Preferably, the red ball adopts water pill.
Preferably, the specification of the red ball is 1.14~1.36g/ balls.
Preferably, the red ball constitutes exterior-applied formulation using degreasing cotton gauze outsourcing, often comprising red 1.14~1.36g of ball or 1;The exterior-applied formulation also includes the lace cord being connected with the degreasing cotton gauze.
The preparation method of above-mentioned gynaecology's pellet ball, comprises the following steps:
Blended successively, granulation, general ball and drying after each bulk drug is ground or crushed, are obtained pellet ball.
The preparation method of gynaecology's pellet ball, specifically includes following steps:
1) 10~100g borneols, 10~100g frankincenses, 10~100g myrrhs and 10~100g dragon's blood are distinguished into finely ground, will It is 60~80 mesh fine powders that 50~200g catechu is crushed;
2) 100~500g kuh-sengs, 50~200g golden cypresses, 50~200g coptiss, 50~200g frutus cnidiis, 50~200g are connected Stick up, 50~200g dandelions and 50~200g rough gentian are crushed respectively, take the fine powder between 100 mesh and 120 mesh;
3) fine powder of all bulk drugs is well mixed, obtains drug powder, a certain amount of drug powder and water are fully mixed Softwood is made in conjunction, and by soft material granulation and after being dried particle of uniform size is chosen, and the particle of selection is inserted to be made after coating pan Inner Coating pan is rotated, by water spray and the prepared water pill of addition drug powder into coating pan repeatedly;
4) water pill is dried, then carries out selecting ball by 1.14~1.36g/ balls, obtain red ball.
Preferably, the preparation method of gynaecology's pellet ball is further comprising the steps of:With degreasing cotton gauze outsourcing pellet ball, obtain The external preparation of red ball, retains the lace cord of 19.5~20.5cm length on the degreasing cotton gauze.
Preferably, the step 3) in, from the granulation of 12~18 mesh sieves.
Preferably, the step 3), 4) in, dry temperature is 50~60 DEG C.
Compared with prior art, the present invention has following beneficial technique effect:
Gynaecology of the present invention pellet ball be according to motherland's traditional medicine theory, using modern science experiment research and Advanced preparation technique, the gynaecology's product with good result developed.Gynaecology's pellet ball of the present invention belongs to pill, by pill Vagina deep is put into, absorbs fast, go directly focus, long action time, and easy to use, reliable effect, are that women is used for Effective product of gynaecological imflammation.Gynaecology's pellet ball of the present invention has clearing heat and detoxicating eliminating dampness, and desinsection is antipruritic, analgesic therapy of invigorating blood circulation, hemostasis The effect of myogenic, relative to conventional antibiotic medicine, toxic and side effect is less.
Gynaecology's pellet ball of the present invention can utilize degreasing cotton gauze outsourcing, and red ball directly acts on uncomfortable place after infiltration, both Therapeutic effect is ensure that, is caused again using more convenient.
The preparation method of gynaecology's pellet ball of the present invention, it is good with preparation process is simple, low for equipment requirements, environment, The advantage of suitable industrial amplification production.
Specific embodiment
With reference to embodiment, the present invention is described in further detail, and described is explanation of the invention rather than limit It is fixed.
(1) prescription foundation and preparation technology
The present invention using kuh-seng, golden cypress, the coptis, frutus cnidii, the capsule of weeping forsythia, dandelion, rough gentian, catechu, frankincense, myrrh, borneol, The taste natural Chinese traditional medicines of dragon's blood 12 are filled a prescription, kuh-seng in we, heat-clearing and damp-drying drug, desinsection, diuresis.Leukorrhea with reddish discharge can be treated, swelling of vulva is cloudy Itch, trichomonas vaginitis.Golden cypress, heat-clearing and damp-drying drug, purging intense heat, except steaming, detoxification sore treatment.The coptis, heat-clearing and damp-drying drug, purging intense heat and detonicating.This three taste Chinese medicine is altogether monarch drug in a prescription, has clearing heat and detoxicating, removing dampness and destroying parasites effect.Frutus cnidii in side, eliminating dampness, wind-dispelling, desinsection.Control eczema of vulva, Married woman's pruritus vulvae;Trichomonas vaginitis.Rough gentian, heat-clearing and damp-drying drug, for swelling of vulva pruritus vulvae, under band, eczema itch.The capsule of weeping forsythia, it is clearing heat and detoxicating, Dispersing swelling and dissipating binds.Dandelion, clearing heat and detoxicating, dispersing swelling and dissipating binds, inducing diuresis for treating strangurtia.This four tastes Chinese medicine is all ministerial drug, has clearing heat and detoxicating, dry The effect of wet desinsection, antipruritic dissipating bind.Catechu in side, with promoting blood circulation and stopping pain, hemostasia and promoting granulation, the effect of hygroscopic sore.Frankincense, promoting blood circulation is fixed Bitterly, detumescence and promoting granulation.Myrrh, scattered stasis pain, detumescence and promoting granulation.Dragon's blood, removing blood stasis and relieving pain, hemostasia and promoting granulation.Borneol, clearing away heat to and alleviating pain.This five The effect of taste Chinese medicine is all adjutant, tool heat-clearing, promoting blood circulation analgesic therapy, hemostasia and promoting granulation.Full side the monarch and his subjects assistant ties in, and heat-clearing solution is played altogether Malicious eliminating dampness, desinsection is antipruritic, analgesic therapy of invigorating blood circulation, the effect of hemostasia and promoting granulation.
Above-mentioned 12 taste Chinese medicine Jing after finely ground, crushing, mixing, is added appropriate purified water to be sufficiently mixed and is made by the present invention After softwood, pelletize, be dried, the particle for choosing uniform small rice grain size inserts coating pan Inner, and rotary machine sprays into a small amount of water, Add appropriate medicinal powder, Jing to operate the general ball for disposably making required size repeatedly, then Jing low temperature dryings, select ball, be obtained pellet Ball, uses for convenience, uses degreasing cotton gauze outsourcing, and retains the lace cord of about 19.5~20.5cm length.
(2) (1000g) is filled a prescription
(800 balls, 1.25g/ balls).
(3) example is prepared
Example 1
(1) borneol, frankincense, myrrh, dragon's blood is finely ground with mortar, it is fine powder (80 mesh) that catechu is crushed.
(2) remaining seven taste Chinese medicine pulverizes and sieves, and medicinal powder should cross 100-120 mesh sieves.
(3) 12 taste Chinese medicine fine powders are well mixed, add appropriate purified water be fully mixed to " hold it is agglomerating, touch it Dissipate " softwood after, from the granulation of 18 mesh sieves, be dried (80 DEG C), choose uniform particle and insert coating pan Inner, rotary machine, A small amount of water is sprayed into, appropriate medicinal powder (referring to 12 taste Chinese medicine fine powders) is added, Jing is operated and disposably made required size repeatedly General ball.
(4) the general Cheng Houying of water pill is dried immediately, and baking temperature is 80 DEG C.
(5) ball is selected, ball weight is 1.25g/ balls.Inner quality standard be 1.25 (1 ± 9%) g, moisture content≤8%.
(6) degreasing cotton gauze outsourcing (ball one is wrapped), and retain the lace cord of 19.5~20.5cm length.
Example 2
(1) borneol, frankincense, myrrh, dragon's blood is finely ground with mortar, it is fine powder (80 mesh) that catechu is crushed.
(2) remaining seven taste Chinese medicine pulverizes and sieves, and medicinal powder should cross 100-120 mesh sieves.
(3) 12 taste Chinese medicine fine powders are well mixed, add appropriate purified water be fully mixed to " hold it is agglomerating, touch it Dissipate " softwood after, from the granulation of 14 mesh sieves, be dried (50 DEG C~60 DEG C), the particle for choosing uniform small rice grain size is inserted Coating pan Inner, rotary machine sprays into a small amount of water, adds appropriate medicinal powder (referring to 12 taste Chinese medicine fine powders), and Jing is operated once repeatedly Property makes the general ball of required size.
(4) the general Cheng Houying of water pill is dried immediately, and baking temperature is 50 DEG C~60 DEG C.
(5) ball is selected, ball weight is 1.25g/ balls.Inner quality standard be 1.25 (1 ± 9%) g, moisture content≤8%.
(6) degreasing cotton gauze outsourcing (ball one is wrapped), and retain the lace cord of 19.5~20.5cm length.
Example 3
(1) borneol, frankincense, myrrh, dragon's blood is finely ground with mortar, it is fine powder (80 mesh) that catechu is crushed.
(2) remaining seven taste Chinese medicine pulverizes and sieves, and medicinal powder should cross 100-120 mesh sieves.
(3) 12 taste Chinese medicine fine powders are well mixed, add appropriate purified water be fully mixed to " hold it is agglomerating, touch it Dissipate " softwood after, from the granulation of 12 mesh sieves, be dried (40 DEG C), choose uniform particle and insert coating pan Inner, rotary machine, A small amount of water is sprayed into, appropriate medicinal powder (referring to 12 taste Chinese medicine fine powders) is added, Jing is operated and disposably made required size repeatedly General ball.
(4) the general Cheng Houying of water pill is dried immediately, and baking temperature is 40 DEG C.
(5) ball is selected, ball weight is 1.25g/ balls.Inner quality standard be 1.25 (1 ± 9%) g, moisture content≤8%.
(6) degreasing cotton gauze outsourcing (ball one is wrapped), and retain the lace cord of 19.5~20.5cm length.
Through contrast, the particle diameter of example 1 is too small, and the pelletization time is most long, further, since the baking temperature of example 1 is too high, borneol is waved Send out serious, Jing after inspection, content of bornyl alcohol is minimum, example 2 is close to the content of bornyl alcohol of example 3.Example 3, pelletizes excessive, particle pine Dissipate, final pelletization number of once pelletizing lacks compared with example 1, example 2;Other example 3 is too low due to baking temperature, and drying time is longer. Through comparing, example 2 is preferred plan.
(4) usage and dosage
After red ball is encapsulated with degreasing cotton gauze obtained in example 2, with 40 DEG C or so of hot-water soak 3-5 minutes, yarn is made Red ball infiltration in cloth, by the gauze for being packaged with red ball vagina depths (arched roof afterwards, away from the deep about 7~10cm of introitus) is inserted, and is deposited Put 4 days (96 hours), then pulled it with subsidiary lace cord, take a day off again with second (per 5 days 1).
(5) antibacterial experiment and toxic and side effect are tested
Jing is checked, it was demonstrated that above-mentioned red ball can effectively suppress Escherichia coli, staphylococcus aureus and Candida albicans, nontoxic Side effect, using safe and effective, as shown in table 1, table 2.
The bacteriostatic experiment result of table 1.
The formulation characteristic of table 2. is analyzed
(6) case using effect
Case 1:
Party so-and-so, female is 37 years old, married, and before half a year, because of pruritus vulvue, leukorrhea is more, have stink, odynuria to remove examination in hospital, examines Break as " vaginitis ", give that " Ampicillin Capsule, Metronidazole Tablet " etc. is oral, external application " clean you cloudy " is rinsed, be used in conjunction 2 days state of an illness without It is clearly better, increases on the contrary, vulva is shown in many red papules, itch, then spiritlessness and weakness, do not feel like eating, afterwards with gynaecology's pellet ball Treatment, with foreign matter when the front lace cord twice that uses is pulled out, after two weeks, patient's pruritus vulvue, leukorrhea are more, have stink, Odynuria is slightly better, spirit, diet is not good enough.It is continuing with 2 months, leukorrhea recovers normal free from extraneous odour, urine is normal.
Case 2:
Lee so-and-so, female, 38 years old.Hypogastralgia more than March, finds abdominal mass January with irregular vagina bleeding.Patient's moon usually Jing is regular.A nearly month total urination time increases, but without urgent urination, odynuria, but lower abdomen enclosed mass oneself is touched when patient's prostration, arrive Examination in hospital, row Visual quality inspection finds " pelvic lump ", before patient's half a year " pregnancy with IVD in situ ", in pregnant more than 70 day row forcep curettage, Because of " tissue residue " massive haemorrhage the row palace of the Qing Dynasty and insertion of intra-uterine device again after one week, the treatment of suffered from postoperative oral antibiotic;Often feel afterwards Weak, menostaxis is not net, but without discomforts such as stomachache, heatings.Since illness, spirit is poor, is off one's feed, and times of defecation increases Plus, in yellowish-brown mushy stool, without tenesmus sense, total urination time increases, Body weight loss about 5kg.Using gynaecology pellet ball before several times Foreign matter is carried when lace cord is pulled out, after one month, urine is normal, without urgent pain, is continuing with 2 months pelvic lump rows Visual quality is checked, substantially diminished.
Case 3:
Often so-and-so, female, 25 years old.It is infertile long after marriage.Vaginal contact bleeding half a year.Patient's eumenorrhea at ordinary times, before 2 years The a small amount of bleeding of vagina after the same branch of a family, not to hospital therapy.Colporrhagia after having sexual intercourse afterwards increases earlier above, and the trace of blood, but nothing are accompanied in leukorrhea Stomachache, without frequent micturition, urgent urination, odynuria, without constipation, edema of lower extremity.Go to see a doctor, be diagnosed as " cervical erosion ".Nothing since morbidity Heating, without nausea, vomiting, two is just normal, and nothing loses weight.It is different using carrying when twice lace cord is pulled out before gynaecology's pellet ball Thing, after one month, after the same branch of a family, without bleeding.After three months, it is discontinued, pregnancy after half a year.
Case 4:
Zhang, female, 40 years old.It was found that abdominal mass 1 year, after significantly increase.Followed by lower abdomen intermittence secret anguish, with dislike The heart, but without vomiting.Unexpected lower abdominal pain before 5 months, heating, it is invalid to take antipyretic, by gynecologial examination, is diagnosed as chronic basin Chamber inflammation acute attack, when pulling out using gynaecology's pellet first three lace cord of ball foreign matter is carried, and using two months, abdominal pain subtracted Gently, two months are continuing with, belly is painless, abdominal mass also fades away.
Case 5:
King so-and-so, women, 36 years old, Zeng Yin " excessive menstruation with progressive 2 years " was admitted to hospital.At ordinary times Jing amounts are medium partially for patient It is many, there are clot and inferior belly gas pain, it is not required to take anodyne.Nearest 1 year starts, and menstrual period extended to 7~10 by original 5~7 days My god.MBV doubles than before, there is big clot.Menstrual period increase earlier above, and not smooth with menstrual period urine.Nearly 2 years above-mentioned symptoms Progressive increases, and bellyache in menstrual period has had influence on normal life, need to take anodyne or intramuscular injection pain killer injection to alleviate.Worked as before half a year Ground discovery and ovarian cyst, oneself touch lower abdomen duck's egg size enclosed mass, inertia, without tenderness.Patient is made using gynaecology's pellet ball Foreign matter is carried when first three time lace cord is pulled out, after one month, urine is normal, and menstrual period foreshorten to 5 days, are continuing with 2 Month, abdominal mass is felt and is substantially diminished.
Case 6
King so-and-so, female, 31 years old, breast lumpd 1 year, and patient has found that the year before right breast has a caking, walnut size, often In the moon premenstrual distending pain, and caking hardens, and then softens after menstruation, and pain relief, is diagnosed irregular menstrual blood in hospital For the proliferation of mammary gland.Recently because of leucorrhea increasing, have stink, odynuria to use gynaecology's pellet ball, using for the first time, lace cord is carried when pulling out Foreign matter, normal using rear leukorrhea twice, urine is normal.Persistently using after two weeks, it is found that chest pain is alleviated, one is then used by Individual month, feel that chest hyperplasia caking diminishes, softens.
In a word, gynaecology of the present invention pellet ball, can effectively clearing heat and detoxicating eliminating dampness, desinsection is antipruritic, and analgesic therapy of invigorating blood circulation, hemostasis is given birth to Flesh;Formulation is simple, easy to use, can the various gynaecological imflammations of effectively treatment;The present invention can be used to treat vaginitis, cervicitis, basin Chamber inflammation, adnexitis, cervical erosion, fibroid, tumour, polyp, the proliferation of mammary gland, metrauxe, endometritis, endometrium Hyperplasia, mullerianosis, and female gynecological inflammation cause it is infertile.

Claims (10)

1. a kind of gynaecology pellet ball, it is characterised in that:The red ball includes following bulk drug:100~500g kuh-sengs, 50~200g are yellow Cypress, 50~200g coptiss, 50~200g frutus cnidiis, 50~200g capsules of weeping forsythia, 50~200g dandelions, 50~200g rough gentian, 50~ 200g catechu, 10~100g frankincenses, 10~100g myrrhs, 10~100g borneols and 10~100g dragon's blood.
2. a kind of gynaecology pellet ball according to claim 1, it is characterised in that:The red ball includes following bulk drug:100~ 200g kuh-sengs, 50~150g golden cypresses, 50~150g coptiss, 50~150g frutus cnidiis, 50~150g capsules of weeping forsythia, 50~150g Pus are public English, 50~150g rough gentian, 50~150g catechu, 10~50g frankincenses, 10~50g myrrhs, 10~50g borneols and 10~50g blood Exhaust.
3. a kind of gynaecology pellet ball according to claim 1, it is characterised in that:The red ball includes following bulk drug:200g is bitter Ginseng, 120g golden cypresses, the 120g coptiss, 120 frutus cnidiis, the 90g capsules of weeping forsythia, 90g dandelions, 80g rough gentian, 100g catechu, 20g frankincenses, 20g Myrrh, 20g borneols and 20g dragon's blood.
4. a kind of gynaecology pellet ball according to claim 1, it is characterised in that:The red ball adopts water pill.
5. a kind of gynaecology pellet ball according to claim 1, it is characterised in that:The specification of the red ball is 1.14~1.36g/ Ball.
6. a kind of gynaecology pellet ball according to claim 5, it is characterised in that:The red ball is constituted using degreasing cotton gauze outsourcing Exterior-applied formulation, often comprising red 1.14~1.36g of ball or 1;The exterior-applied formulation also includes the cotton being connected with the degreasing cotton gauze Cotton rope.
7. the preparation method of gynaecology as claimed in claim 1 pellet ball, it is characterised in that:Comprise the following steps:
Blended successively, granulation, general ball and drying after each bulk drug is ground or crushed, are obtained pellet ball.
8. method according to claim 7, it is characterised in that:The preparation method of the red ball, specifically includes following steps:
1) 10~100g borneols, 10~100g frankincenses, 10~100g myrrhs and 10~100g dragon's blood are distinguished into finely ground, by 50~ It is 60~80 mesh fine powders that 200g catechu is crushed;
2) by 100~500g kuh-sengs, 50~200g golden cypresses, 50~200g coptiss, 50~200g frutus cnidiis, 50~200g capsules of weeping forsythia, 50~200g dandelions and 50~200g rough gentian are crushed respectively, take the fine powder between 100 mesh and 120 mesh;
3) fine powder of all bulk drugs is well mixed, obtains drug powder, drug powder and water are sufficiently mixed and make softwood, will Particle of uniform size is chosen after soft material granulation and drying, the particle of selection is inserted after coating pan Inner rotates coating pan, led to Cross and spray water into coating pan repeatedly and add drug powder that water pill is obtained;
4) water pill is dried, then carries out selecting ball by 1.14~1.36g/ balls, obtain red ball.
9. method according to claim 8, it is characterised in that:The preparation method of the red ball is further comprising the steps of:With Degreasing cotton gauze outsourcing pellet ball, obtains the external preparation of red ball, the cotton thread with 19.5~20.5cm length on the degreasing cotton gauze Rope.
10. method according to claim 8, it is characterised in that:The step 3) in, from the granulation of 12~18 mesh sieves;Institute State step 3), 4) in, dry temperature is 50~60 DEG C.
CN201611024209.7A 2016-11-17 2016-11-17 Gynecological pill and preparation method thereof Pending CN106620101A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111840452A (en) * 2020-09-17 2020-10-30 赵铁楼 Non-dissolving non-disintegrating gynecological external pill and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102327360A (en) * 2011-08-31 2012-01-25 浙江大学 Gel preparation for treating cervical erosion and preparation method thereof
CN102949501A (en) * 2011-08-25 2013-03-06 彭军 External washing lotion for treating gynecological inflammation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102949501A (en) * 2011-08-25 2013-03-06 彭军 External washing lotion for treating gynecological inflammation
CN102327360A (en) * 2011-08-31 2012-01-25 浙江大学 Gel preparation for treating cervical erosion and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
张伟明等: "阴炎净洗液的制备及抑菌效果研究", 《湖南中医杂志》 *
王加维等: "麒麟消糜散治疗宫颈糜烂88例", 《湖北中医杂志》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111840452A (en) * 2020-09-17 2020-10-30 赵铁楼 Non-dissolving non-disintegrating gynecological external pill and preparation method thereof

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