CN101596250B - Traditional Chinese medicine suppository for treating intrauterine inflammation or intrauterine inflammation infertility - Google Patents

Traditional Chinese medicine suppository for treating intrauterine inflammation or intrauterine inflammation infertility Download PDF

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CN101596250B
CN101596250B CN2009100166538A CN200910016653A CN101596250B CN 101596250 B CN101596250 B CN 101596250B CN 2009100166538 A CN2009100166538 A CN 2009100166538A CN 200910016653 A CN200910016653 A CN 200910016653A CN 101596250 B CN101596250 B CN 101596250B
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parts
inflammation
radix
uterine cavity
infertility
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CN101596250A (en
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潘士安
潘蓓蓓
邢玉辉
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Abstract

The invention discloses a traditional Chinese medicine suppository for treating intrauterine inflammation or intrauterine inflammation infertility, which is prepared from the following raw materials according to parts by weight: 10 to 30 parts of catechu, 10 to 30 parts of borneol, 10 to 30 parts of alum, 3 to 9 parts of licorice, 7 to 21 parts of psoralea corylifolia, 7 to 21 parts of rhubarb, 3 to 9 parts of senega, 3 to 9 parts of common cnidium fruit, 7 to 21 parts of desertliving cistanche, 7 to 21 parts of rhizoma coptidis and 7 to 21 parts of amur corktree bark. The invention combines all the medicinals which are complementary to each other, have the effects of promoting blood circulation, removing stasis of blood, eliminating blood stasis, promoting tissue regeneration, eliminating dampness, decreasing swelling, promoting tissue generation and promoting wound healing, can clean the uterine cavity, kill viruses and various pathogenic microorganisms, and eliminate the intrauterine inflammation so as to be beneficial for pregnancy. The invention has the advantages of low cost, no any toxic or side effect, good curative effect, short treatment course, and the like.

Description

A kind of Chinese medicine suppository for the treatment of inflammation infertility in interior inflammation of uterine cavity or the uterine cavity
Technical field
The present invention relates to a kind of Chinese medicine suppository for the treatment of inflammation infertility in interior inflammation of uterine cavity or the uterine cavity.
Background technology
Infertility is child-bearing period women's a kind of commonly encountered diseases, a frequently-occurring disease, and with man and wife's coupledom after marriage, it is main that two to three years time still can not become pregnant, and does not have seasonal.The paathogenic factor of primary disease is many-sided, and wherein, modal is that inflammation causes infertilely in the uterine cavity, therefore, eliminates that inflammation is the critical treatment means of treatment infertility in the uterine cavity.Clinically at present the employing taken antibiotic method more, but therapeutic effect is unsatisfactory, and because of taking the extensive application antibiotic, side effect is more, and the growth to fetus after anemia of pregnant woman's pregnancy also has than bad influence.Multiple medicine for external use is also arranged in the prior art, but have mostly that effect is undesirable, problem such as obstinate, cost height, the course of treatment are long, produce effects slowly.
Summary of the invention
At above-mentioned prior art, the invention provides a kind of Chinese medicine suppository for the treatment of inflammation infertility in interior inflammation of uterine cavity or the uterine cavity.
The present invention is achieved by the following technical solutions:
A kind of Chinese medicine suppository for the treatment of inflammation infertility in interior inflammation of uterine cavity or the uterine cavity, be to make: 10~30 parts in catechu, 10~30 parts of Borneolum Syntheticums, 10~30 parts in Alumen by the raw material of following weight portion, 3~9 parts in Radix Glycyrrhizae, 7~21 parts of Fructus Psoraleaes, 7~21 parts of Radix Et Rhizoma Rhei, 3~9 parts of Radix Polygalaes, 3~9 parts of Fructus Cnidiis, 7~21 parts of Herba Cistanches, 7~21 parts of Rhizoma Coptidis, 7~21 parts of Cortex Phellodendris.
Preferred following component: 20 parts in catechu, 20 parts of Borneolum Syntheticums, 20 parts in Alumen, 6 parts in Radix Glycyrrhizae, 14 parts of Fructus Psoraleaes, 14 parts of Radix Et Rhizoma Rhei, 6 parts of Radix Polygalaes, 6 parts of Fructus Cnidiis, 14 parts of Herba Cistanches, 14 parts of Rhizoma Coptidis, 14 parts of Cortex Phellodendris.
A kind of preparation method for the treatment of the Chinese medicine suppository of inflammation infertility in interior inflammation of uterine cavity or the uterine cavity: the usefulness by raw material in the prescription is measured catechu, Borneolum Syntheticum, Alumen, Radix Glycyrrhizae, Fructus Psoraleae, Radix Et Rhizoma Rhei, Radix Polygalae, Fructus Cnidii, Herba Cistanches, pulverize and be powdery, cross 200 mesh sieves, mixing is made medicated powder; Usefulness by raw material in the prescription is measured Rhizoma Coptidis, Cortex Phellodendri, and decocting (amount of water is 10~50 times of amounts of raw material), concentrated gets medicinal liquid; Gained medicated powder is mixed with medicinal liquid, make pill and get final product, the heavily about 6g of every ball.
Dosage form of the present invention is the towed suppository of cotton rope, it is pill external gauze parcel, the medical thin silk thread ligation of reuse is solid, stays about 20 centimetres on line, during use, put on aseptic fingerstall, pill is pushed in the uterine cavity, and potion took off after 3 days, and change dressings 5 a course of treatment, promptly 15 days courses of treatment, the patient should determine whether to carry out next course of treatment according to the state of an illness and therapeutic effect.State of an illness the lighter can become pregnant 2~3 courses of treatment, and the heavy person of the state of an illness becomes pregnant 3~5 courses of treatment.In beginning in 3~4 days medication of the clean back of menstruation.
Pharmacological property of the present invention is as follows:
Catechu---meridian distribution of property and flavor: bitter, puckery, be slightly cold, return lung meridian.The living infantile malnutrition of controling the inferior is wet mashed.Effect: can rush down can remove, can be dry can be hard, the hemostasis of promoting the production of body fluid, is held back skin ulcer and is stopped blooding heat-clearing and toxic substances removing, removing dampness pathogenic fire purging, promoting granulation and relieving pain.
Borneolum Syntheticum---meridian distribution of property and flavor: hot, bitter, be slightly cold GUIXIN, spleen, lung hydrocarbon.Effect: the refreshment of having one's ideas straightened out, clearing away heat to alleviate pain is used for skin infection and swells and ache, and does not hold back after bursting.Heat-clearing and toxic substances removing, erosion prevention and muscle growing effect are arranged.Effect: the stagnated fire of loosing, logical all keys, suppress the growth of escherichia coli and staphylococcus aureus.The transdermal enhancing effect of Borneolum Syntheticum can also increase the storage storehouse effect of intact skin and destratum corneum skin thereof mainly at the horny layer of skin, makes subcutaneous telangiectasis simultaneously, makes medicine be easy to enter blood circulation, and then medicine is played a role.
Alumen---nature and flavor: acid, cold, acid has the astringent therapy effect, has the detoxifcation parasite killing, and is quick-fried wet antipruritic, hemostasis antidiarrheal, the effect of heat clearing away expectorant.Have relieving iching by astringing, detoxifcation doctor's skin ulcer, hold back and rush down hemostasis, the heat clearing away toxic action of dispelling, can absorb partial secretions also energy antipruritic, have the local vascular of preventing and break, the little blood vessel of partial fracture is stopped blooding.Studies confirm that in recent years, Alumen also have effects such as antibiotic, anti-trichomonas vaginitis.
Radix Glycyrrhizae---meridian distribution of property and flavor: sweet, flat, GUIXIN, lung, spleen, stomach warp.Function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.Its energy Yiqi and vein recovery can increase partial asthenia of qi and blood situation, helps impaired blood capillary circulation and recovers normal.
Fructus Psoraleae---meridian distribution of property and flavor: acrid in the mouth; Bitter; Warm in nature, kidney; Pericardium; Spleen; Stomach; Lung meridian.Effect: reinforcing the kidney and supporting YANG; Helping inspiration to relieve asthma; Warming spleen and stopping diarrha, controlling nocturnal emission with astringent drugs reducing urination.Cure mainly: insufficiency of kidney-YANG; Below element deficiency and cold; Chills and pain of the waist and kness; The sexual impotence essence; Frequent micturition; The enuresis; Failure of the kidney in receiving QI; Dyspnea due to deficiency is more than; Asthenia of both the spleen and kidney; The stool chronic diarrhea; Vitiligo; Speckle is bald; Psoriasis.
Radix Et Rhizoma Rhei---meridian distribution of property and flavor: hardship, cold.Return spleen, stomach, large intestine, liver, pericardium channel.Function cures mainly: purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.Be used for the excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, heat in blood is told nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle is treated skin ulcer, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.Radix et Rhizoma Rhei (stir-fried with wine) is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.Be used for the conjunctival congestion pharyngeal swelling, gingivitis.Radix Et Rhizoma Rhei rushes down exerts oneself to delay eliminating fire and detoxication.Be used for pathogenic fire,toxin and furuncles.The hemostasis of charred Radix Et Rhizoma Rhei cooling blood and removing stasis.Be used for heat in blood stasis of blood bleeder is arranged.Multiple Gram-positives such as staphylococcus aureus, Hemolytic streptococcus and negative bacterium all there are stronger antibacterial action, multiple fungus is also had in various degree inhibitory action.
Radix Polygalae---meridian distribution of property and flavor: bitter, hot, tepor.GUIXIN, kidney, lung meridian.Function cures mainly: the Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm detumescence.Be used for the insomnia and dreamful sleep that disarmony between the heart and kidney causes, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, breast swell and pain.Be used for cold-damp and go into cellulitis subcutaneous ulcer toxic swelling due to the network, no matter effect for oral administration, that external application all has reducing swelling and alleviating pain makes that blood vessel recovers normal in the congested uterine cavity.
Fructus Cnidii---meridian distribution of property and flavor: warm in nature, acrid in the mouth, hardship are returned kidney channel.Function cures mainly: warming the kidney to invigorate YANG, dampness is dispeled the wind, parasite killing.Be used for sexual impotence, cold womb, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago; External treatment vulval eczema, married woman's pudendal pruritus, trichomonal vaginitis.
Herba Cistanches---meridian distribution of property and flavor: return through sweet, salty temperature.Return kidney, large intestine channel.Function cures mainly: kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation.Be used for sexual impotence, infertile, soreness of the waist and knees, muscles and bones is unable, the dryness of the intestine constipation.How dry general medea is, and only Herba Cistanches is sweet and tepor is salty and moist, and property is gentle, has YANG invigorating and not dry, moist and oiliness characteristics, thereby makes the blood vessel circulation both smooth and unlikely too fast, both increases blood circulation and don't as for excessive hyperemia and reach.
Rhizoma Coptidis---meridian distribution of property and flavor: hardship, cold.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Function cures mainly: heat clearing and damp drying, eliminating fire and detoxication.Be used for damp and hot feeling of fullness, the vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed, conjunctival congestion, the carbuncle furuncle is quenched one's thirst in toothache; External treatment eczema, eczema, auditory meatus is suppurated.The kind clear part of the body cavity above the diaphragm housing the heart and lungs of Rhizoma Coptidis (processed with wine) is burning hot.Be used for conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Be used for cold and heat and tie mutually, damp and hot middle resistance, feeling of fullness vomiting.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.Be used for incoordination between the liver and stomach, the vomiting acid regurgitation.Has broad spectrum antibacterial function.
Cortex Phellodendri---meridian distribution of property and flavor: hardship, cold.Return kidney, urinary bladder channel.Function cures mainly: heat clearing and damp drying, pathogenic fire purging are removed and are steamed, and skin ulcer is treated in detoxifcation.Be used for damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity (warding off), hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.The stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.Be used for hyperactivity of fire caused by deficiency of YIN, the night sweat hectic fever due to YIN-deficiency.Its blood circulation that can prevent newly-established blood capillary is hemorrhage, and external can also promote the effect that subcutaneous hemorrhage absorbs.
All medicine compatibilities complement each other among the present invention, have the effect of blood circulation promoting and blood stasis dispelling, promoting tissue regeneration by removing blood stasis, damp eliminating detumescence, promoting tissue regeneration and ulcer healing, can clean cavity of uterus, and kill virus and various pathogenic microorganism are eliminated the interior inflammation of uterine cavity, become pregnant thereby benefit.Therapeutic effect of the present invention is good, treats 196 examples altogether, cure 150 surplus example, effective percentage is more than 90%, the present invention has advantages such as cost is low, without any side effects, therapeutic effect is good, short treating period.
The specific embodiment
The present invention is further illustrated below in conjunction with embodiment and case:
Embodiment 1: prepare a kind of Chinese medicine suppository for the treatment of inflammation infertility in interior inflammation of uterine cavity or the uterine cavity, and raw materials used as follows: catechu 10g, Borneolum Syntheticum 30g, Alumen 10g, Radix Glycyrrhizae 9g, Fructus Psoraleae 7g, Radix Et Rhizoma Rhei 21g, Radix Polygalae 3g, Fructus Cnidii 9g, Herba Cistanches 7g, Rhizoma Coptidis 21g, Cortex Phellodendri 7g.
Preparation method: the usefulness by raw material in the prescription is measured catechu, Borneolum Syntheticum, Alumen, Radix Glycyrrhizae, Fructus Psoraleae, Radix Et Rhizoma Rhei, Radix Polygalae, Fructus Cnidii, Herba Cistanches, pulverizes to be powdery, crosses 200 mesh sieves, and mixing is made medicated powder; Usefulness by raw material in the prescription is measured Rhizoma Coptidis, Cortex Phellodendri, and decocting (amount of water is 10 times of amounts of raw material), concentrated gets medicinal liquid; Gained medicated powder is mixed with medicinal liquid, make pill, the heavily about 6g of every ball.
Use: pill external gauze parcel, the medical thin silk thread ligation of reuse is solid, stays about 20 centimetres on line, during use, puts on aseptic fingerstall, and pill is pushed in the uterine cavity, and potion took off after 3 days, 15 days courses of treatment.
Embodiment 2: prepare a kind of Chinese medicine suppository for the treatment of inflammation infertility in interior inflammation of uterine cavity or the uterine cavity, and raw materials used as follows: catechu 30g, Borneolum Syntheticum 10g, Alumen 30g, Radix Glycyrrhizae 3g, Fructus Psoraleae 21g, Radix Et Rhizoma Rhei 7g, Radix Polygalae 9g, Fructus Cnidii 3g, Herba Cistanches 21g, Rhizoma Coptidis 7g, Cortex Phellodendri 21g.Preparation method is with embodiment 1.
Embodiment 3: prepare a kind of Chinese medicine suppository for the treatment of inflammation infertility in interior inflammation of uterine cavity or the uterine cavity, and raw materials used as follows: catechu 20g, Borneolum Syntheticum 20g, Alumen 20g, Radix Glycyrrhizae 6g, Fructus Psoraleae 14g, Radix Et Rhizoma Rhei 14g, Radix Polygalae 6g, Fructus Cnidii 6g, Herba Cistanches 14g, Rhizoma Coptidis 14g, Cortex Phellodendri 14g.Preparation method is with embodiment 1.
Embodiment 4: prepare a kind of Chinese medicine suppository for the treatment of inflammation infertility in interior inflammation of uterine cavity or the uterine cavity, and raw materials used as follows: catechu 25g, Borneolum Syntheticum 15g, Alumen 25g, Radix Glycyrrhizae 8g, Fructus Psoraleae 10g, Radix Et Rhizoma Rhei 10g, Radix Polygalae 4g, Fructus Cnidii 7g, Herba Cistanches 18g, Rhizoma Coptidis 18g, Cortex Phellodendri 10g.Preparation method is with embodiment 1.
Case 1: Lee, the woman, 30 years old, married 5 years, the man and wife lives together together, unpregnancy, through doing gynecologial examination, inflammation is heavier in the uterine cavity, and other are normal, and the bridegroom's or husband's side is normal, is diagnosed as struvite infertile.Through with 3 courses of treatment of the present invention, conceived after 3 months, after give birth to a healthy boy baby smoothly.
Case 2: Zhang, the woman, 30 years old, married 5 years, the man and wife lives together, unpregnancy, Gr1 P0 AB1 before half a year.Check to find through doing, leucorrhea abnormal, menstrual period are irregular, the soreness of waist often, lower body has bearing down.Examination per vagina: the secretions amount is more, frowziness, the time fulminant leucorrhagia with yellowish discharge is arranged, the bridegroom's or husband's side is no abnormal.Through with 5 courses of treatment of the present invention, conceived after 5 months, after give birth to a healthy girl baby smoothly.
Case 3: Fang, the woman, 36 years old, marry surplus in the of 10 year, menstruation is undesired always, leucorrhea has abnormal flavour, amount is many, the time contact bleeding is arranged, soreness of waist pain, the lower abdomen creeping chill, with place, hands palpation public region than other local colds; Through seeking medical advice in many ways, effect is bad.Through with 4 courses of treatment of the present invention, above-mentioned symptom disappears, 2 months at interval, use 2 courses of treatment again, conceived after 3 months, after give birth to a healthy boy baby smoothly.
Case 4: section certain, the woman, 25 years old, married before 3 years, the man and wife lives together after marriage, conceived always, the patient has the dysmenorrhea medical history, the fulminant leucorrhagia with yellowish discharge spy is many at ordinary times, through use outer washing medicine, white fulminant leucorrhagia with yellowish discharge alleviates, abnormal flavour alleviates to some extent, but often recurs.After with 6 courses of treatment of the present invention, above-mentioned symptom disappears, and conceived after 3 months, after give birth to a healthy boy baby smoothly.

Claims (3)

1. a Chinese medicine suppository for the treatment of inflammation infertility in interior inflammation of uterine cavity or the uterine cavity is characterized in that, is to be made by the raw material of following weight portion: 10~30 parts in catechu, 10~30 parts of Borneolum Syntheticums, 10~30 parts in Alumen, 3~9 parts in Radix Glycyrrhizae, 7~21 parts of Fructus Psoraleaes, 7~21 parts of Radix Et Rhizoma Rhei, 3~9 parts of Radix Polygalaes, 3~9 parts of Fructus Cnidiis, 7~21 parts of Herba Cistanches, 7~21 parts of Rhizoma Coptidis, 7~21 parts of Cortex Phellodendris.
2. a kind of Chinese medicine suppository for the treatment of inflammation infertility in interior inflammation of uterine cavity or the uterine cavity according to claim 1 is characterized in that, is to be made by the raw material of following weight portion: 20 parts in catechu, 20 parts of Borneolum Syntheticums, 20 parts in Alumen, 6 parts in Radix Glycyrrhizae, 14 parts of Fructus Psoraleaes, 14 parts of Radix Et Rhizoma Rhei, 6 parts of Radix Polygalaes, 6 parts of Fructus Cnidiis, 14 parts of Herba Cistanches, 14 parts of Rhizoma Coptidis, 14 parts of Cortex Phellodendris.
3. the described a kind of preparation method for the treatment of the Chinese medicine suppository of inflammation infertility in inflammation in the uterine cavity or the uterine cavity of claim 1, it is characterized in that: the usefulness by raw material in the prescription is measured catechu, Borneolum Syntheticum, Alumen, Radix Glycyrrhizae, Fructus Psoraleae, Radix Et Rhizoma Rhei, Radix Polygalae, Fructus Cnidii, Herba Cistanches, pulverize and be powdery, cross 200 mesh sieves, mixing is made medicated powder; Usefulness by raw material in the prescription is measured Rhizoma Coptidis, Cortex Phellodendri, and decocting, concentrated gets medicinal liquid; Gained medicated powder is mixed with medicinal liquid, make pill and get final product.
CN2009100166538A 2009-07-01 2009-07-01 Traditional Chinese medicine suppository for treating intrauterine inflammation or intrauterine inflammation infertility Expired - Fee Related CN101596250B (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1593555A (en) * 2004-07-06 2005-03-16 西安五洲皮肤美容研究所 Indiscerptible and built in type Chinese traditional preparation for gynecopathy and its preparation process

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1593555A (en) * 2004-07-06 2005-03-16 西安五洲皮肤美容研究所 Indiscerptible and built in type Chinese traditional preparation for gynecopathy and its preparation process

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
唐德才.中药栓剂应用进展.《海峡药学》.2005,第17卷(第6期),第203-206页. *

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