CN1066189A - A kind of preparation method of anti-cancer powder - Google Patents

Abstract

The invention belongs to the medicine compound method, particularly use the method for prepared from traditional Chinese medicines anti-cancer powder.The present invention is with fragrant eight lotuses, Polyporus etc. nine flavor Chinese herbal medicine, through decocting in water, alcohol leaching, sour molten neutralization, concentrate, series of steps such as drying, make a kind of taking convenience, clothes have no side effect effective percentage, the anti-cancer powder that late result is good for a long time.

Description

A kind of preparation method of anti-cancer powder

The invention belongs to the medicine compound method, particularly use the method for prepared from traditional Chinese medicines anti-cancer powder.

Cancer is the high a kind of disease of mortality rate in the world, is the arch enemy of man, and many in the world countries all drop into a large amount of manpowers, and material resources are carried out anticancer research work, does not still have outstanding effectiveness so far.Chinese herbal medicine is a huge treasure-house of China, and using the Chinese herbal treatment tumor has long history in China, makes great efforts to excavate this treasure-house, uses the herbal control cancer, is the responsibility that we should use up the mankind.

Purpose of the present invention is the preparation method of a kind of anticancer herbal drug electuary of research, to make the medicine of the taking convenience that can be used for treatment of cancer.

Anti-cancer powder of the present invention is by nine flavor prepared from traditional Chinese medicines, its prescription is: fragrant eight lotuses 15～30, Herba Agrimoniae 15～30, Herba Solani Lyrati root 15～30, Radix Patriniae 15～30, Herba Hedyotidis Diffusae 15～30, Radix Sophorae Tonkinensis 9～15, Polyporus 15～30, Rhizoma Smilacis Chinensis 15～20,15～30 parts of Radix Isatidiss, above-mentioned prescription is processed through following these steps to:

A, Polyporus, Rhizoma Smilacis Chinensis, Radix Isatidis hybrid process are become 40 order powder, add 6～9 times of amounts of water (the doubly amount of the dose that feeds intake-down with) and soak 5～8 hours after-filtration, filtrate 1 and medicinal residues 1; The ethanol that medicinal residues 1 is added 6～8 times of amounts soaks 4～5 hours after-filtration, gets filtrate 2 and medicinal residues 2; With 6～11 times of water gagings of medicinal residues 2 processing, under 50～80 ℃, boil 2～3 hours after-filtration, get filtrate 3 and medicinal residues 3; Medicinal residues 3 are added 6～11 times of water gagings, after boiling 2～3 hours under 70～90 ℃, boiled 1～2 hour at 90～99 ℃ again, filter, get filtrate 4; With above-mentioned filtrate 1～4 mixing, under 50～70 ℃, be concentrated into the dose that feeds intake behind the recovery ethanol, cool off, add the ethanol of 4～6 times of amounts again, precipitate down at 10～14 ℃ and remove slag, get Polyporus and filter filtrate;

B, with fragrant eight lotuses, Herba Agrimoniae, Herba Solani Lyrati root, Radix Patriniae, Herba Hedyotidis Diffusae, the Radix Sophorae Tonkinensis hybrid process becomes 40 order powder, adding 6～11 times of amounts of water (the doubly amount of the dose that feeds intake-together following) soaked 5～6 hours, under 45～60 ℃, boiled 2～3 hours then, again 80～90 ℃ boil 1～2 hour after, filter, get filtrate 5 and medicinal residues 5; Medicinal residues 5 are added 6～11 times of water gagings, transfer to PH=4～6, under 40～60 ℃, soaked 3～4 hours, boiled 1～2 hour at 60～75 ℃ then with dilute sulfuric acid, again 80～99 ℃ boil 1～2 hour after, filter, filtrate 6; It is extremely neutral that filtrate 5 and 6 is mixed the acid of using in the sodium hydroxide neutralization filtrate, is concentrated into the dose that feeds intake again under 50～60 ℃, cools off, and adds the ethanol of 1～2 times of amount, precipitates down at 10～14 ℃ and remove slag, and gets fragrant eight lotus filtrates;

C, Polyporus filtrate and fragrant eight lotus filtrates are mixed the back reclaim ethanol, be concentrated into the thick paste shape under 50～70 ℃, add 3 times of amounts of dose Icing Sugar that all feeds intake, make soft material, 16 mesh sieves that nuzzle up are made granule, promptly get this electuary after the drying.

Instructions of taking: each 3～9 grams, every day three times, warm boiled water.

The example treatment surplus clinical 300 of this anti-cancer powder is observed, and obeys avirulence for a long time, has no side effect, and harmless to Liver and kidney, effective percentage reaches more than 91%, and late result is better, and part patient cures.As blue * *, man 50 years old, certain power depot water conservancy project was gastric cancer late period through five tame hospital diagnosis before 20 years, fully recover after 1 year 03 months through clothes this product, now still was still living and in good health.Ten thousand * *, the woman, 42 years old, certain worker of pharmaceuticals was the uterus cancroid III phase after diagnosing before 16 years, clinical symptoms complete obiteration after clothes this product, not recurrence so far, still working as usual.

Embodiment:

I, Polyporus, Rhizoma Smilacis Chinensis, Radix Isatidis, Xiang Balian, red crowned crane, Herba Solani Lyrati root, Radix Patriniae, Herba Hedyotidis Diffusae, Radix Sophorae Tonkinensis=6: 4: 5: 8.5: 5: 6: 5.5: 7: 3.

I a, Polyporus, Rhizoma Smilacis Chinensis, Radix Isatidis are processed into 40 order powder, add 3 times of water gagings of dosage (3 flavor) and soak 5 hours after-filtration, filtrate 1 and medicinal residues 1; The ethanol that medicinal residues 1 is added 3 times of amounts soaks 4 hours after-filtration, gets filtrate 2 and medicinal residues 2; Medicinal residues 2 are added 10 times of water gagings, boil 2 hours after-filtration with 60 ℃, filtrate 3 and medicinal residues 3; Medicinal residues 3 are added 10 times of water gagings, boil with 70 ℃ and under 98 ℃, boiled 1 hour again after 3 hours, filter, filtrate 4, medicinal residues 4 abandon; Above-mentioned filtrate 1～4 is mixed, reclaim ethanol after, be concentrated into the dose that feeds intake with 55 ℃, cooling, add again 5 times of amount ethanol 10 ℃ down precipitation remove slag, Polyporus filtrate.

I b, all the other 6 flavor medicine hybrid process such as fragrant eight lotuses are become 40 order powder, add 10 times of water gagings of dosage (6 flavor) and soaked 5 hours, under 60 ℃, boiled 2 hours then, under 80 ℃, boiled 2 hours again, filter, filtrate 5 and medicinal residues 5; Medicinal residues 5 are added 10 times of water gagings, transfer to PH=4, under 60 ℃, soaked 4 hours, boiled 2 hours at 70 ℃ then with dilute sulfuric acid, again 99 ℃ boil 2 hours after, filter, filtrate 6, abandon medicinal residues 6; Filtrate 5 and 6 is mixed with the acid in the sodium hydroxide neutralization filtrate to neutrality, be concentrated into the dose that feeds intake at 50 ℃, cooling adds the ethanol of the dose that feeds intake, 10 ℃ of precipitations down, remove slag, fragrant eight lotus filtrates.

I c, Polyporus filtrate and fragrant eight lotus filtrates are mixed the back reclaim ethanol, be concentrated at 70 ℃, the thick paste shape adds the Icing Sugar of the 3 times of amounts of dose that all feed intake, and makes soft material, and 16 mesh sieves that nuzzle up are made granule, promptly get this electuary after the drying.

II, Polyporus, Rhizoma Smilacis Chinensis, Radix Isatidis, Xiang Balian, Herba Agrimoniae, Herba Solani Lyrati root, Radix Patriniae, Herba Hedyotidis Diffusae, Radix Sophorae Tonkinensis=8: 5: 7.5: 4.5: 8.3: 7: 7: 5: 4.2.

II a, Polyporus, Rhizoma Smilacis Chinensis, Radix Isatidis are processed into 40 order powder, add 6 times of water gagings of the dose that feeds intake (3 flavor) and soak 7.5 hours after-filtration, filtrate 1 and medicinal residues 1; Medicinal residues 1 are added 5.5 times of amount ethanol soak 5 hours after-filtration, get filtrate 2 and medicinal residues 2; Medicinal residues 2 are added 10 times of water gagings, under 80 ℃, boil 3 hours after-filtration, get filtrate 3 and medicinal residues 3; Medicinal residues 3 are added 10 times of water gagings, after boiling 2 hours under 90 ℃, under 90 ℃, boil filtration in 2 hours again, get filtrate 4, lose medicinal residues 4; With above-mentioned filtrate 1～4 mix reclaim ethanol after, be concentrated into the dose that feeds intake with 70 ℃, cooling adds 5 times of amount ethanol again 14 ℃ of precipitations down, remove slag, Polyporus filtrate.

II b, all the other 6 flavor medicine hybrid process such as fragrant eight lotuses are become 40 order powder, add 11 times of water loggings of the dose that feeds intake (6 flavor) 6 hours, under 45 ℃, boiled 3 hours then, under 90 ℃, boiled 1 hour again, filter, filtrate 5 and medicinal residues 5; Medicinal residues 5 are added 10 times of water gagings, transfer to PH=6, under 40 ℃, soaked 3 hours, boiled 1 hour at 60 ℃ then with dilute sulfuric acid, again 80 ℃ boil 1 hour after, filter, filtrate 6, abandon medicinal residues 6; Filtrate 5 and 6 is mixed with the acid in the sodium hydroxide neutralization filtrate to neutrality, be concentrated into the dose that feeds intake under 60 ℃, cooling adds the ethanol of 5 times of amounts, 14 ℃ of precipitations down, remove slag, fragrant eight lotus filtrates.

II c, Polyporus filtrate and fragrant eight lotus filtrates are mixed the back reclaim ethanol, be concentrated into the thick paste shape under 50 ℃, add the Icing Sugar of the 3 times of amounts of dose that all feed intake, make soft material, 16 mesh sieves that nuzzle up are made granule, promptly get this electuary after the drying.

Claims (1)

1, a kind of preparation method of Chinese herbal medicine anti-cancer powder, filling a prescription is fragrant eight lotuses 15～30, Herba Agrimoniae 15～30, Herba Solani Lyrati root 15～30, Radix Patriniae 15～30, Herba Hedyotidis Diffusae 15～30, Radix Sophorae Tonkinensis 9～15, Polyporus 15～30, Rhizoma Smilacis Chinensis 12～20,15～30 parts of Radix Isatidiss, be processed into electuary through following steps:

A, Polyporus, Rhizoma Smilacis Chinensis, Radix Isatidis hybrid process are become 40 order powder, add 6～9 times of amounts of water (the doubly amount of the dose that feeds intake-down with) and soak 5～8 hours after-filtration, filtrate 1 and medicinal residues 1; The ethanol that medicinal residues 1 is added 6～8 times of amounts soaks 4～5 hours after-filtration, gets filtrate 2 and medicinal residues 2; With 6～11 times of water gagings of medicinal residues 2 processing, under 50～80 ℃, boil 2～3 hours after-filtration, get filtrate 3 and medicinal residues 3; Medicinal residues 3 are added 6～11 times of water gagings, after boiling 2～3 hours under 70～90 ℃, boiled 1～2 hour at 90～99 ℃ again, filter, get filtrate 4, above-mentioned filtrate 1～4 is mixed, under 50～70 ℃, be concentrated into the dose that feeds intake behind the recovery ethanol, cooling, the ethanol that adds 4～6 times of amounts again, precipitation removes slag under 10～14 ℃, gets Polyporus filter filtrate;

B, fragrant eight lotuses, Herba Agrimoniae, Herba Solani Lyrati root, Radix Patriniae, Herba Hedyotidis Diffusae, Radix Sophorae Tonkinensis hybrid process are become 40 order powder, adding 6～11 times of amounts of water (the doubly amount of the dose that feeds intake-together following) soaked 5～6 hours, under 45～60 ℃, boiled 2～3 hours then, 80～90 ℃ boil 1～2 hour after, filter, get filtrate 5 and medicinal residues 5; Medicinal residues 5 are added 3～6 times of water gagings, transfer to PH=4～6 with dilute sulfuric acid, under 40～60 ℃, soaked 3～4 hours, then 60～75 ℃ boil 1～2 hour after, filter, get filtrate 6, it is extremely neutral that filtrate 5 and 6 is mixed the acid of using in the sodium hydroxide neutralization filtrate, is concentrated into the dose that feeds intake again under 50～60 ℃, cooling, the ethanol that adds 1～2 times of amount, precipitation removes slag under 10～14 ℃, gets fragrant eight lotus filtrates;

C, Polyporus filtrate and fragrant eight lotus filtrates are mixed the back reclaim ethanol, be concentrated into the thick paste shape under 50～70 ℃, add 3 times of amounts of dose Icing Sugar that all feeds intake, make soft material, 16 mesh sieves that nuzzle up are made granule, promptly get this electuary after the drying.