CN106588908A - 用于介入治疗和根除癌症的ite - Google Patents
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- CN106588908A CN106588908A CN201611027233.6A CN201611027233A CN106588908A CN 106588908 A CN106588908 A CN 106588908A CN 201611027233 A CN201611027233 A CN 201611027233A CN 106588908 A CN106588908 A CN 106588908A
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111067895A (zh) * | 2020-01-14 | 2020-04-28 | 广东医科大学 | Ite在制备预防和/或治疗心肺循环系统疾病的药物中的应用 |
| CN113292570A (zh) * | 2021-05-27 | 2021-08-24 | 山东大学 | 一类含有2,4-噻唑环的化合物及其制备方法和应用 |
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| JP2011503232A (ja) | 2007-11-20 | 2011-01-27 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド | 免疫応答の調節 |
| ES2791684T3 (es) | 2009-11-02 | 2020-11-05 | Ariagen Inc | ITE para la intervención y erradicación del cáncer |
| US10632106B2 (en) | 2009-11-02 | 2020-04-28 | Ariagen, Inc. | Methods of cancer treatment with 2-(1′H-Indole-3′-carbonyl)-thiazole-4-carboxylic acid methyl ester |
| AR079814A1 (es) | 2009-12-31 | 2012-02-22 | Otsuka Pharma Co Ltd | Compuestos heterociclicos, composiciones farmaceuticas que los contienen y sus usos |
| EP3191481B1 (en) | 2014-09-12 | 2020-11-25 | Ariagen, Inc. | Efficient and scalable systhesis of 2-(1'h-indole-3'-carbonyl)-thiazole-4-carboxylic acid methyl ester and its structural analogs |
| CA2980730A1 (en) | 2015-03-23 | 2016-09-29 | The Brigham And Women's Hospital, Inc. | Tolerogenic nanoparticles for treating diabetes mellitus |
| CN108239083B (zh) * | 2016-12-26 | 2021-08-17 | 阿里根公司 | 芳香烃受体调节剂 |
| TWI674260B (zh) * | 2017-02-01 | 2019-10-11 | 德商菲尼克斯製藥股份有限公司 | 芳基烴受體(AhR)調節劑化合物 |
| TWI752155B (zh) * | 2017-02-01 | 2022-01-11 | 德商菲尼克斯製藥股份有限公司 | 芳香烴受體(AhR)調節劑化合物 |
| WO2019099977A2 (en) * | 2017-11-20 | 2019-05-23 | Ariagen, Inc. | Indole compounds and their use |
| KR20210151951A (ko) * | 2019-04-15 | 2021-12-14 | 아리아젠, 인크. | 키랄 인돌 화합물 및 그 용도 |
| US11136318B2 (en) | 2019-06-21 | 2021-10-05 | Noramco, Llc | Processes for the preparation of aryl hydrocarbon receptor ligands |
| US20210300912A1 (en) | 2019-12-20 | 2021-09-30 | Ikena Oncology, Inc. | Aryl hydrocarbon receptor (ahr) agonists and uses thereof |
| KR20220150280A (ko) | 2019-12-20 | 2022-11-10 | 이케나 온콜로지, 인코포레이티드 | E.g. 혈관신생 관련 또는 염증성 장애의 치료를 위한 아릴 탄화수소 수용체 (ahr) 작용제로서의 4-페닐-n-(페닐)티아졸-2-아민 유도체 및 관련 화합물 |
| WO2022133480A1 (en) | 2020-12-18 | 2022-06-23 | Ikena Oncology, Inc. | Aryl hydrocarbon receptor (ahr) agonists and uses thereof |
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| WO2009070645A1 (en) * | 2007-11-29 | 2009-06-04 | The Ohio University Research Foundation | Indoles, derivatives, and analogs thereof and uses thereof |
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| US5811425A (en) | 1997-03-04 | 1998-09-22 | Abbott Laboratories | Heterocyclic compounds as COX-2 inhibitors |
| US7709520B2 (en) * | 2000-10-06 | 2010-05-04 | The Texas A&M University System | Diindolylmethane and C-substituted diindolylmethane compositions and methods for the treatment of multiple cancers |
| US7419992B2 (en) | 2001-02-14 | 2008-09-02 | Wisconsin Alumni Research Foundation | Use of aryl hydrocarbon receptor ligand as a therapeutic intervention in angiogenesis-implicated disorders |
| US20020177594A1 (en) | 2001-03-14 | 2002-11-28 | Curtin Michael L. | Inhibitors of histone deacetylase |
| WO2003068742A1 (en) | 2002-02-12 | 2003-08-21 | Wisconsin Alumni Research Foundation | Synthesis of indole thiazole compounds as ligands for the ah receptor |
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| CN111067895A (zh) * | 2020-01-14 | 2020-04-28 | 广东医科大学 | Ite在制备预防和/或治疗心肺循环系统疾病的药物中的应用 |
| CN113292570A (zh) * | 2021-05-27 | 2021-08-24 | 山东大学 | 一类含有2,4-噻唑环的化合物及其制备方法和应用 |
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| US8604067B2 (en) | 2013-12-10 |
| US20200323827A1 (en) | 2020-10-15 |
| US10195182B2 (en) | 2019-02-05 |
| EP2496081A4 (en) | 2013-05-01 |
| US20170333401A1 (en) | 2017-11-23 |
| NZ702914A (en) | 2016-05-27 |
| NZ599896A (en) | 2015-09-25 |
| US20120214853A1 (en) | 2012-08-23 |
| AU2010313622B2 (en) | 2014-08-14 |
| EP2496081A1 (en) | 2012-09-12 |
| EP3689347A1 (en) | 2020-08-05 |
| JP2013509411A (ja) | 2013-03-14 |
| ES2791684T3 (es) | 2020-11-05 |
| US9694000B2 (en) | 2017-07-04 |
| WO2011053466A1 (en) | 2011-05-05 |
| US20160136139A1 (en) | 2016-05-19 |
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