CN106577720A - Use method of composite alcohol disinfection liquid and composite quaternary ammonium salt disinfection liquid - Google Patents
Use method of composite alcohol disinfection liquid and composite quaternary ammonium salt disinfection liquid Download PDFInfo
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- CN106577720A CN106577720A CN201610408798.2A CN201610408798A CN106577720A CN 106577720 A CN106577720 A CN 106577720A CN 201610408798 A CN201610408798 A CN 201610408798A CN 106577720 A CN106577720 A CN 106577720A
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- Prior art keywords
- quaternary ammonium
- ammonium salt
- compound
- disinfection liquid
- composite
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
- A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
- A01N47/44—Guanidine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/12—Quaternary ammonium compounds
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- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The present invention belongs to the technical field of medical disinfection agents, and more particularly relates to a use method of a composite alcohol disinfection liquid and a composite quaternary ammonium salt disinfection liquid, wherein the composite alcohol disinfection liquid is prepared from the following components by weight: 2% of a sterilization agent, 0.1-0.3% of a penetration moisturizing agent, and 97.9-97.7% of a solvent, and the composite quaternary ammonium salt disinfection liquid is prepared from the following components by weight: 0.2% of a sterilization agent, 0.1-0.3% of a solubilizing agent, 0.1-0.2% of essence, and 99.6-99.3% of a solvent. According to the present invention, the composite alcohol disinfection liquid and the composite quaternary ammonium salt disinfection liquid are used to regularly and alternately used (every one week or every one month), such that the generation of resistance of bacteria to the disinfection liquid can be avoided, and the generation of resistance bacteria can be effectively avoided.
Description
Technical field
The invention belongs to the technical field of medical disinfectant, more particularly to a kind of compound alcohol disinfection solution and compound season
The using method of ammonium salt disinfectant solution.
Background technology
Antibacterial is to report in the Study Progress on Resistance (Chinese Journal of Nosocomiology the 1st phase of volume 22 in 2012) of disinfectant
The current chlorine-containing disinfectant for using, aldehyde disinfectant, quaternary ammonium disinfectant, iodine and iodine-containing disinfectant etc. have all been generated
The present situation of resistance to antibacterial.Practice also it was demonstrated that no matter which kind of disinfectant, if long-term be used alone, can all produce resistance to antibacterial, thus
Reduce even losing Disinfection Effect.
Compound alcohol disinfection solution and compound quaternary ammonium salt disinfectant, the two can be used in surface disinfection, and effectively can kill
Go out pathogenic entero becteria, pyococcuss, saccharomytes and common bacteria in nosocomial infection.If individually life-time service is wherein
A kind of disinfectant carry out surface disinfection, will certainly also produce resistance to antibacterial.It has been investigated that, if conjunction is periodically used alternatingly
Alcohol disinfection solution and compound quaternary ammonium salt disinfectant liquid carry out disinfection, so that it may be prevented effectively from the generation of resistance to antibacterial.
The content of the invention
It is an object of the invention to overcome above-mentioned technical defect, there is provided one kind avoids thalline from producing resistance to disinfectant solution
The composite disinfectant and its using method of property.
To achieve these goals, the present invention is by the following technical solutions realizing:A kind of compound alcohol disinfection solution,
It is formulated by the composition of following weight portion:Antibacterial 2%, infiltration wetting agent 0.1%-0.3%, solvent 97.9%-
97.7%;
Wherein, the antibacterial is chlorhexidine gluconate or chlorhexidine acetate;Infiltration wetting agent is D-panthenol or the third three
Alcohol;Solvent is the mixture of ethanol and deionized water.
Using method:Surface disinfection, without the need for dilution, directly immersion or cleaning disinfection, act on 1-3 minutes to stock solution.
A kind of compound quaternary ammonium salt disinfectant, is formulated by the composition of following weight portion:Antibacterial 0.2%, solubilizing agent
0.1%-0.3%, essence 0.1%-0.2%, solvent 99.6%-99.3%;
Wherein antibacterial be benzalkonium chloride, benzalkonium bromide, last of the ten Heavenly stems Matsubain, in Deciquam it is any two or more
Mixture;Solubilizing agent is castor oil hydrogenated polyethers (CO-40);Solvent is deionized water.
Using method:Surface disinfection, without the need for dilution, directly immersion or cleaning disinfection, act on 10 minutes stock solution.
Compound alcohol disinfection solution and compound quaternary ammonium salt disinfectant are used alternatingly method:Week about or one month alternately
Carried out disinfection using compound alcohol disinfection solution and compound quaternary ammonium salt disinfectant.
By using above-mentioned technical scheme, the invention has the beneficial effects as follows:The present invention using compound alcohol disinfection solution and
Compound quaternary ammonium salt disinfectant regular (week about or every other month) is used alternatingly and thalline can be avoided to produce resistance to disinfectant solution
Property, the generation of resistance to antibacterial can be prevented effectively from.
Specific embodiment
Technological means, creation characteristic, reached purpose and effect to make present invention realization is easy to understand, with reference to
Specific embodiment, is expanded on further the present invention.
Embodiment 1
The compound alcohol disinfection solution that the present invention is provided, is formulated by the composition of following weight portion:Gluconic acid chlorine oneself
Fixed 2%, D-panthenol 0.1%, ethanol 68%, deionized water 29.9%.Preparation method:D-panthenol, ethanol, gluconic acid chlorine oneself
Surely stir in sequentially adding deionized water, fill after mix homogeneously.Using method:Surface disinfection, stock solution need not dilute, directly
Immersion or cleaning disinfection are connect, 1-3 minutes are acted on.
Compound quaternary ammonium salt disinfectant, is formulated by the composition of following weight portion:Benzalkonium bromide 0.05%, Deciquam
0.15%th, CO-40 0.1%, essence 0.1%, deionized water 99.6%.Preparation method:Benzalkonium bromide, Deciquam, CO-
40th, essence sequentially adds stirring and dissolving in deionized water, fill after mix homogeneously.Using method:Surface disinfection, stock solution without
Dilution is needed, directly immersion or cleaning disinfection, acted on 10 minutes.
The method that compound alcohol disinfection solution, compound quaternary ammonium salt disinfectant are used alternatingly:When surface disinfection is carried out, the
One week, the 3rd week, the 5th week ... wiped or soaked using compound alcohol disinfection solution (or compound quaternary ammonium salt disinfectant) and is disappeared
Poison, second week, 4th week, the 6th week ... wiped using compound quaternary ammonium salt disinfectant (or compound alcohol disinfection solution) or
Soaking disinfection.Compound alcohol disinfection solution, compound quaternary ammonium salt disinfectant is used alternatingly week about to carry out disinfection.
Embodiment 2
The compound alcohol disinfection solution that the present invention is provided, is formulated by the composition of following weight portion:Gluconic acid chlorine oneself
Fixed 2%, glycerol 0.3%, ethanol 70%, deionized water 27.7%.Preparation method:D-panthenol, ethanol, gluconic acid chlorine oneself
Surely stir in sequentially adding deionized water, fill after mix homogeneously.Using method:Surface disinfection, stock solution need not dilute, directly
Immersion or cleaning disinfection are connect, 1-3 minutes are acted on.
Compound quaternary ammonium salt disinfectant, is formulated by the composition of following weight portion:Benzalkonium chloride 0.08%, Deciquam
0.12%th, CO-40 0.1%, essence 0.1%, deionized water 99.6%.Preparation method:Benzalkonium chloride, Deciquam, CO-
40th, essence sequentially adds stirring and dissolving in deionized water, fill after mix homogeneously.Using method:Surface disinfection, stock solution without
Dilution is needed, directly immersion or cleaning disinfection, acted on 10 minutes.
The method that compound alcohol disinfection solution, compound quaternary ammonium salt disinfectant are used alternatingly:When surface disinfection is carried out, the
One month, the 3rd month, the 5th month ... wiped using compound alcohol disinfection solution (or compound quaternary ammonium salt disinfectant) or
Soaking disinfection, second month, the 4th month, the 6th month ... using compound quaternary ammonium salt disinfectant (or compound alcohol disinfecting
Liquid) wiped or soaking disinfection.Compound alcohol disinfection solution, compound quaternary ammonium salt disinfectant is used alternatingly every other month to be carried out
Sterilization.
The above, the only specific embodiment of the present invention, but protection scope of the present invention is not limited thereto, any
Those familiar with the art the invention discloses technical scope in, change or replacement can be readily occurred in, should all be contained
Cover within protection scope of the present invention.Therefore, protection scope of the present invention described should be defined by scope of the claims.
Claims (9)
1. a kind of compound alcohol disinfection solution, it is characterised in that:It is formulated by the composition of following weight portion:By following weight
The composition of part is formulated:Antibacterial 2%, infiltration wetting agent 0.1%-0.3%, solvent 97.9%-97.7%.
2. a kind of compound alcohol disinfection solution according to claim 1, it is characterised in that:The antibacterial is gluconic acid chlorine
Oneself determines or chlorhexidine acetate.
3. a kind of compound alcohol disinfection solution according to claim 1, it is characterised in that:Infiltration wetting agent is D-panthenol or third
Triol.
4. a kind of compound alcohol disinfection solution according to claim 1, it is characterised in that:Solvent is ethanol and deionized water
Mixture.
5. a kind of compound quaternary ammonium salt disinfectant, it is characterised in that:It is formulated by the composition of following weight portion:Antibacterial
0.2%th, solubilizing agent 0.1%-0.3%, essence 0.1%-0.2%, solvent 99.6%-99.3%.
6. a kind of compound quaternary ammonium salt disinfectant according to claim 5, it is characterised in that:Antibacterial is benzalkonium chloride, benzene
Any two or more the mixture pricked in bromine ammonium, last of the ten Heavenly stems Matsubain, Deciquam.
7. a kind of compound quaternary ammonium salt disinfectant according to claim 5, it is characterised in that:Solubilizing agent is poly- for castor oil hydrogenated
Ether (CO-40).
8. a kind of compound quaternary ammonium salt disinfectant according to claim 5, it is characterised in that:Solvent is deionized water.
9. be combined alcohol disinfection solution and compound quaternary ammonium salt disinfectant is used alternatingly method:Week about or a month alternating makes
Carried out disinfection with compound alcohol disinfection solution and compound quaternary ammonium salt disinfectant.
Priority Applications (1)
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CN201610408798.2A CN106577720A (en) | 2016-06-13 | 2016-06-13 | Use method of composite alcohol disinfection liquid and composite quaternary ammonium salt disinfection liquid |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110692652A (en) * | 2019-10-21 | 2020-01-17 | 上海洒家宠物用品有限公司 | Household deodorizing and odor-retaining disinfectant for pets and preparation method thereof |
CN111306980A (en) * | 2020-03-16 | 2020-06-19 | 中冷智元环境技术有限公司 | Bacteriostatic cooling tower with accelerated cooling |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN101112624A (en) * | 2002-08-20 | 2008-01-30 | Alda医药公司 | Broad spectrum sanitizer |
CN101500556A (en) * | 2006-06-02 | 2009-08-05 | 纽约市哥伦比亚大学托管会 | Compositions containing zinc salts for coating medical articles |
-
2016
- 2016-06-13 CN CN201610408798.2A patent/CN106577720A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101112624A (en) * | 2002-08-20 | 2008-01-30 | Alda医药公司 | Broad spectrum sanitizer |
CN101500556A (en) * | 2006-06-02 | 2009-08-05 | 纽约市哥伦比亚大学托管会 | Compositions containing zinc salts for coating medical articles |
Non-Patent Citations (1)
Title |
---|
刘明洁: "醋酸氯己定和苯扎溴铵局部皮肤灭菌效果比较", 《内蒙古医学杂志》 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110692652A (en) * | 2019-10-21 | 2020-01-17 | 上海洒家宠物用品有限公司 | Household deodorizing and odor-retaining disinfectant for pets and preparation method thereof |
CN111306980A (en) * | 2020-03-16 | 2020-06-19 | 中冷智元环境技术有限公司 | Bacteriostatic cooling tower with accelerated cooling |
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