CN106568624A - A pathological specimen pretreatment device - Google Patents
A pathological specimen pretreatment device Download PDFInfo
- Publication number
- CN106568624A CN106568624A CN201610909200.8A CN201610909200A CN106568624A CN 106568624 A CN106568624 A CN 106568624A CN 201610909200 A CN201610909200 A CN 201610909200A CN 106568624 A CN106568624 A CN 106568624A
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- China
- Prior art keywords
- cylinder
- specimen
- layer
- reagent
- processing device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 230000001575 pathological effect Effects 0.000 title claims abstract description 32
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 63
- 238000000034 method Methods 0.000 claims abstract description 63
- 230000008569 process Effects 0.000 claims abstract description 57
- 239000010410 layer Substances 0.000 claims abstract description 41
- 239000011229 interlayer Substances 0.000 claims abstract description 27
- 239000007788 liquid Substances 0.000 claims abstract description 12
- 230000002572 peristaltic effect Effects 0.000 claims abstract description 8
- 238000007781 pre-processing Methods 0.000 claims description 24
- 238000001514 detection method Methods 0.000 claims description 14
- 230000018044 dehydration Effects 0.000 claims description 12
- 238000006297 dehydration reaction Methods 0.000 claims description 12
- 238000012545 processing Methods 0.000 claims description 11
- 238000002347 injection Methods 0.000 claims description 4
- 239000007924 injection Substances 0.000 claims description 4
- 230000001681 protective effect Effects 0.000 claims description 4
- 238000011900 installation process Methods 0.000 claims description 3
- 230000007306 turnover Effects 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 238000007599 discharging Methods 0.000 abstract 1
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 5
- 238000002372 labelling Methods 0.000 description 5
- 238000012423 maintenance Methods 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 3
- 230000007170 pathology Effects 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 238000007654 immersion Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 238000002604 ultrasonography Methods 0.000 description 2
- 230000009471 action Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005194 fractionation Methods 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
Abstract
A pathological specimen pretreatment device is disclosed. The device includes a box body. Three separating layers are disposed in the box body. The first separating layer is a reagent placing layer, the second separating layer is a treatment jar layer, and the third separating layer is a specimen interlayer of an automatic jar. Five treatment jars are disposed at intervals in the treatment jar layer and include a jar to be treated, an immobilization jar, a dewatering jar, an embedding jar and a treated jar to be picked which are respectively connected to a reagent bottle. Liquid discharging pipes of the reagent bottles are provided with peristaltic pumps and are communicated with liquid inlets of the five treatment jars. Liquid feeding pipes of the reagent bottles are communicated with liquid outlets of the five treatment jars. The bottoms of the five treatment jars are respectively provided with an ultrasonic generator. A specimen clamping apparatus used for clamping a specimen in or out the five treatment jars is disposed in the specimen interlayer. The device shortens the total time for pathological specimen immobilization, dewatering and embedding to 20-60 min, and a full process is automatically operated and free of labor operation. The device is time-saving, labor-saving and cost-saving.
Description
Technical field
The present invention relates to surgery Pathology pre-processing device, more particularly to a kind of Pathologic specimen pre-processing device.
Background technology
At present, for the flow process of surgery Pathology analysis is：After pathologic specimen is taken out from body operation, Jing Guoqing
Wash --- fix that (usually 10% formalin, i.e. formaldehyde press 1 with water into liquid medicine：9 proportional arrangement, 12-24 is little for immersion
When) --- dehydration (each immersion 2 hours in the ethanol of 80%, 90%, 95%, 100% various concentration) --- waxdip, embedding
(paraffin of 52C 3 hours), transfers to pathological section, is finally analyzed to Pathology Doctors ' after process.
In current processing procedure, the total duration into fixation, dehydration, embedding at least wants 24 hours, while adding
Artificial participation is changed a job sequence, and the job placement of hospital, must at least take three working days.The disease of operation is known for being eager
For the doctor and patient of reason result, it is a wait that is very very long, time-consuming, expending energy and money.
The content of the invention
The purpose of the present invention is the drawbacks described above for prior art, there is provided a kind of Pathologic specimen pre-processing device.Originally set
It is standby that Pathologic specimen is shorten to 20 to 60 minutes into the total duration of fixed, dehydration, embedding, and overall process is automation mechanized operation,
Manually need not participate in.Save time, save power, cost-effective.
To solve the drawbacks described above of prior art, the technical scheme that the present invention is provided is：A kind of Pathologic specimen pretreatment sets
It is standby, including casing, three interlayers in the casing, are provided with, first interlayer is reagent placed layer, and second interlayer is to process cylinder
Layer, the 3rd interlayer is the specimen interlayer of automatic cylinder body, and five process cylinders, five process are arranged at intervals with the process cylinder layer
Cylinder is respectively pending cylinder, stationary cylinder, dehydration cylinder, embedding cylinder and process and completes cylinder to be taken, the pending cylinder, stationary cylinder, de-
Water vat, embedding cylinder and process complete cylinder to be taken and respectively connect a reagent bottle, and the drain pipe road of the reagent bottle is provided with compacted
Dynamic pump, the drain pipe road of the reagent bottle connects with the inlet openings of five process cylinders, the input duct of the reagent bottle and five
The liquid outlet connection of cylinder is processed, five bottoms for processing cylinder are equipped with a supersonic generator, in the specimen interlayer
The specimen clamp device that ticket holder is entered or pressed from both sides out this five process cylinders is provided with, the RFID for track record on the reagent bottle, is posted
Code.
Improve as one kind of Pathologic specimen pre-processing device of the present invention, in the specimen interlayer, be additionally provided with a chain of command
Plate, the control panel are provided with display screen.
Improve as one kind of Pathologic specimen pre-processing device of the present invention, the pending cylinder, stationary cylinder, dehydration cylinder, bag
Bury cylinder and process completes temperature and concentration detection sensor are separately installed with cylinder to be taken, reach the accurate adjustment of various parameters.
Improve as one kind of Pathologic specimen pre-processing device of the present invention, five described process be equipped with a cylinder on cylinder
Lid, the cylinder cap are connected with the process cylinder by pivot pin.
As Pathologic specimen pre-processing device of the present invention one kind improve, the peristaltic pump by five process cylinders reagent with
The reagent of reagent bottle is exchanged automatically, reaches the equilibrium of temperature, concentration.
Improve as one kind of Pathologic specimen pre-processing device of the present invention, the specimen clamp device includes a column, described
Column is provided with a jig arm, and the end of the jig arm is provided with a finger cylinder, and the lower end of the column is arranged on wall box
Slide rail on, the column can be moved left and right along the slide rail, the jig arm by be arranged on the column driving up and down dress
Put control to move up and down.
Improve as one kind of Pathologic specimen pre-processing device of the present invention, one is stamped on the process cylinder layer and can be turned over upwards
Rise to cover to process cylinder layer or downwardly turn over and open the protective door for processing cylinder layer, the reagent placed layer is provided with placed layer door, institute
State and on specimen interlayer, be stamped a protecting cover that can dig opening upwards.
Improve as one kind of Pathologic specimen pre-processing device of the present invention, the side of the casing is provided with and off switch, institute
State.
Improve as one kind of Pathologic specimen pre-processing device of the present invention, the posterolateral arm of the casing is provided with process cylinder layer
Baffle plate, the baffle plate are used for the dividing plate of installation process cylinder layer.
As Pathologic specimen pre-processing device of the present invention one kind improve, be equipped with five reagent bottle liquid injection port and
The handle for conveniently picking and placeing, is provided with a breach on front side of the casing upper end.
Compared with prior art, it is an advantage of the invention that：
1st, this equipment enters fixed, dehydration Pathologic specimen, the total duration of embedding shorten to 20 to 60 minutes, and overall process
For automation mechanized operation, it is not necessary to artificial to participate in.Save time, save power, save whole social cost.
2nd, peristaltic pump is used, the reagent for processing cylinder is exchanged automatically with the reagent of reagent bottle, reach temperature, concentration
It is balanced；
3rd, using the ultrasound wave of certain frequency, accelerate the motion of reagent molecule and specimen cell, reagent is rapidly entered carefully
Nodule structure, is rapidly completed processing procedure；
4th, 5 process cylinders are separately installed with temperature and concentration detection sensor, reach the accurate adjustment of various parameters；
5th, RFID codes are sticked during reagent bottle labeling, that is, it is random and have track record.There is new wanting to labelling machine
Ask.This equipment can be monitored to reagent when in use, it is ensured that reagent is from regular channel and in guarantee date；
6th, whole processing procedure adopts Single-chip Controlling, whole to participate in without the need for operator, possesses reagent concentration, temperature
Automatic detection, the automatic detection of sample disposal program, fault detect of equipment etc.；
7th, using the long-range monitoring of WIFI.The true and false and state, equipment situation, remote assistance, maintenance or behaviour including reagent
Make the license detection of personnel.
Description of the drawings
Further details of is made to technique effect of the invention and its beneficial with specific embodiment with reference to the accompanying drawings just below
Description, wherein：
Fig. 1 is fractionation structural representation of the present invention.
Fig. 2 is dimensional structure diagram of the present invention.
Reference title：1st, casing 2, reagent placed layer 3, process cylinder layer 4, specimen interlayer 5, reagent bottle 6, compacted
Dynamic pump 7, drain pipe road 8, input duct 9, supersonic generator 10, specimen clamp device 11, control panel 12, display screen
13rd, cylinder cap 14, pivot pin 15, protective door 16, placed layer door 17, protecting cover 18, on and off switch 19, process cylinder layer baffle plate 20,
Dividing plate 21, liquid injection port 22, handle 23, breach 101, column 102, jig arm 103, finger cylinder 104, slide rail.
Specific embodiment
Just the invention will be further described with specific embodiment with reference to the accompanying drawings below, but embodiments of the present invention not office
It is limited to this.
As depicted in figs. 1 and 2, a kind of Pathologic specimen pre-processing device, including casing, is provided with three interlayers in casing 1, the
One interlayer is reagent placed layer 2, and to process cylinder layer 3, the 3rd interlayer is the specimen interlayer 4 of automatic cylinder body to second interlayer,
Process and in cylinder layer 3, be arranged at intervals with five process cylinders, five process cylinder be respectively pending cylinder 31, stationary cylinder 32, dehydration cylinder 33,
Embedding cylinder 34 and process complete cylinder to be taken 35, and pending cylinder 31, stationary cylinder 32, dehydration cylinder 33, embedding cylinder 34 and process complete to treat
Take cylinder 35 and respectively connect a reagent bottle 5, the drain pipe road of reagent bottle 5 is provided with peristaltic pump 6, the drain pipe road 7 of reagent bottle 5
Connect with the inlet opening of five process cylinders, the input duct 8 of reagent bottle 5 is connected with the liquid outlet of five process cylinders, five process
The bottom of cylinder is equipped with a supersonic generator 9, and the mark for ticket holder being entered or being pressed from both sides out this five process cylinders is provided with specimen interlayer 4
This clamp device 10, posts the RFID codes for track record on reagent bottle 5.RFID codes are sticked, can be random and has tracking
Record.There is new requirement to labelling machine.This equipment can be monitored to reagent when in use, it is ensured that reagent is from regular canal
Road and in guarantee date.
Preferably, a control panel 11 is additionally provided with specimen interlayer 4, control panel 11 is provided with display screen 12.It is whole to locate
Reason process adopts Single-chip Controlling, whole to participate in without the need for operator, possesses the automatic detection of reagent concentration, temperature, at specimen
The automatic detection of reason program, fault detect of equipment etc..
Preferably, pending cylinder 31, stationary cylinder 32, dehydration cylinder 33, embedding cylinder 34 and process is completed in cylinder to be taken 35 respectively
Temperature and concentration detection sensor are installed, the accurate adjustment of various parameters is reached.
Preferably, a cylinder cap 13 is equipped with five process cylinders, cylinder cap 13 is connected with cylinder is processed by pivot pin 14.
Preferably, peristaltic pump 6 by five process cylinders reagent exchanged with the reagent of reagent bottle 5 automatically, reach temperature,
The equilibrium of concentration.
Preferably, specimen clamp device 10 includes a column 101, and column 101 is provided with a jig arm 102, the end of jig arm 102
A finger cylinder 103 is provided with, the lower end of column 101 is arranged on the slide rail 104 on 1 side wall of casing, and column 101 can be along slide rail
104 move left and right, and jig arm 102 is moved up and down by the up-down drive device control being arranged on column 101.
Preferably, process one is stamped on cylinder layer 3 to dig upwards to cover process cylinder layer or downwardly turn over opening and process cylinder
The protective door 15 of layer, reagent placed layer 2 are provided with placed layer door 16, are stamped one and can dig opening upwards on specimen interlayer 4
Protecting cover 17.The cross section of protecting cover 17 is in D fonts, and is made using transparent component.When the machine works, it can be seen that the inside
Action.
Preferably, the side of casing 1 is provided with and off switch 18, is provided with WIFI receptors in casing 1.Using the long-range of WIFI
Monitoring.The true and false and state, equipment situation, remote assistance, maintenance or the license of operator detection including reagent.
Preferably, the posterolateral arm of casing 1 is provided with process cylinder layer baffle plate 19, baffle plate 19 be used for installation process cylinder layer 2 every
Plate 20.
Preferably, liquid injection port 21 and the handle 22 for conveniently picking and placeing are equipped with five reagent bottle 6, casing is set on front side of 1 upper end
There is a breach 23.Control panel 11 is concordant with the breach 23, is easy to operating display.
The present invention has advantages below：
1st, this equipment enters fixed, dehydration Pathologic specimen, the total duration of embedding shorten to 20 to 60 minutes, and overall process
For automation mechanized operation, it is not necessary to artificial to participate in.Save time, save power, save whole social cost.
2nd, peristaltic pump is used, the reagent for processing cylinder is exchanged automatically with the reagent of reagent bottle, reach temperature, concentration
It is balanced.
3rd, using the ultrasound wave of certain frequency, accelerate the motion of reagent molecule and specimen cell, reagent is rapidly entered carefully
Nodule structure, is rapidly completed processing procedure.
4th, 5 process cylinders are separately installed with temperature and concentration detection sensor, reach the accurate adjustment of various parameters.
5th, RFID codes are sticked during reagent bottle labeling, that is, it is random and have track record.There is new wanting to labelling machine
Ask.This equipment can be monitored to reagent when in use, it is ensured that reagent is from regular channel and in guarantee date.
6th, whole processing procedure adopts Single-chip Controlling, whole to participate in without the need for operator, possesses reagent concentration, temperature
Automatic detection, the automatic detection of sample disposal program, fault detect of equipment etc..
7th, using the long-range monitoring of WIFI.The true and false and state, equipment situation, remote assistance, maintenance or behaviour including reagent
Make the license detection of personnel.
Although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
Understand various changes, modification, replacement can be carried out to these embodiments in the case of the principle and structure without departing from the present invention
And modification, the scope of the present invention limited by claims and its equivalency range.
Claims (10)
1. a kind of Pathologic specimen pre-processing device, including casing, it is characterised in that be provided with three interlayers in the casing, first
Individual interlayer is reagent placed layer, and, to process cylinder layer, the 3rd interlayer is the specimen interlayer of automatic cylinder body, the place for second interlayer
Reason cylinder layer in be arranged at intervals with five process cylinders, five process cylinder be respectively pending cylinder, stationary cylinder, dehydration cylinder, embedding cylinder and
Process completes cylinder to be taken, and the pending cylinder, stationary cylinder, dehydration cylinder, embedding cylinder and process complete cylinder to be taken and respectively connect one
Individual reagent bottle, the drain pipe road of the reagent bottle are provided with peristaltic pump, the drain pipe road of the reagent bottle and five process cylinders
Inlet opening is connected, and the input duct of the reagent bottle is connected with the liquid outlet of five process cylinders, five bottoms for processing cylinder
A supersonic generator is equipped with, is provided with the specimen interlayer and the specimen that ticket holder enters or press from both sides out this five process cylinders is clamped
Put, on the reagent bottle, post the RFID codes for track record.
2. Pathologic specimen pre-processing device according to claim 1, it is characterised in that be additionally provided with the specimen interlayer
Control panel, the control panel are provided with display screen.
3. Pathologic specimen pre-processing device according to claim 2, it is characterised in that the pending cylinder, stationary cylinder, de-
Water vat, embedding cylinder and process complete temperature and concentration detection sensor are separately installed with cylinder to be taken, and reach the essence of various parameters
Really adjust.
4. Pathologic specimen pre-processing device according to claim 3, it is characterised in that five described process are equipped with cylinders
One cylinder cap, the cylinder cap are connected with the process cylinder by pivot pin.
5. Pathologic specimen pre-processing device according to claim 4, it is characterised in that the peristaltic pump processes cylinders by five
Reagent exchanged with the reagent of reagent bottle automatically, reach the equilibrium of temperature, concentration.
6. Pathologic specimen pre-processing device according to claim 5, it is characterised in that the specimen clamp device includes that stands
Post, the column are provided with a jig arm, and the end of the jig arm is provided with a finger cylinder, and the lower end of the column is arranged on casing
On slide rail on the wall of side, the column can be moved left and right along the slide rail, and the jig arm is upper and lower on the column by being arranged on
Driving means control is moved up and down.
7. Pathologic specimen pre-processing device according to claim 1, it is characterised in that being stamped on the process cylinder layer can
The protective door for processing cylinder layer is opened to dig upwards to cover to process cylinder layer or downwardly turn over, the reagent placed layer is provided with placement
Layer door, is stamped a protecting cover that can dig opening upwards on the specimen interlayer.
8. Pathologic specimen pre-processing device according to claim 1, it is characterised in that the side of the casing is provided with power supply
Switch, is provided with WIFI receptors in the casing.
9. Pathologic specimen pre-processing device according to claim 1, it is characterised in that the posterolateral arm of the casing is provided with
Cylinder layer baffle plate is processed, the baffle plate is used for the dividing plate of installation process cylinder layer.
10. Pathologic specimen pre-processing device according to claim 1, it is characterised in that be all provided with five reagent bottle
There are liquid injection port and the handle for conveniently picking and placeing, on front side of the casing upper end, be provided with a breach.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610909200.8A CN106568624A (en) | 2016-10-18 | 2016-10-18 | A pathological specimen pretreatment device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610909200.8A CN106568624A (en) | 2016-10-18 | 2016-10-18 | A pathological specimen pretreatment device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106568624A true CN106568624A (en) | 2017-04-19 |
Family
ID=58533267
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610909200.8A Pending CN106568624A (en) | 2016-10-18 | 2016-10-18 | A pathological specimen pretreatment device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106568624A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108760443A (en) * | 2018-05-18 | 2018-11-06 | 漯河医学高等专科学校 | A kind of fixing means of Pathologic specimen |
| CN113251751A (en) * | 2021-05-18 | 2021-08-13 | 枣庄科技职业学院 | Pathological section gradient dewatering device |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2927032Y (en) * | 2006-07-20 | 2007-07-25 | 陈锦源 | Pathological tissue treater |
| CN201378123Y (en) * | 2009-04-16 | 2010-01-06 | 赵晓辉 | Six-cylinder automatic water extractor for paraffin wax film production of biological tissue sample patch |
| CN102455261A (en) * | 2010-10-30 | 2012-05-16 | 杨燕 | Dewatering device |
| CN102879251A (en) * | 2012-09-18 | 2013-01-16 | 湖北阳光神琦医用科技有限公司 | Dehydrating and dyeing dual-function machine and control method thereof |
| CN203069607U (en) * | 2013-01-23 | 2013-07-17 | 深圳市亚辉龙生物科技有限公司 | Western blot automatic detection device |
| CN103884565A (en) * | 2014-04-02 | 2014-06-25 | 深圳市达科为医疗科技有限公司 | Pathological staining machine |
| CN105974894A (en) * | 2016-04-25 | 2016-09-28 | 温冬梅 | Medical laboratory automated assembly line reagent automatic supply method and system |
| CN206146706U (en) * | 2016-10-18 | 2017-05-03 | 东莞市鸥翼实业有限公司 | Pathology sample pre treatment device |
-
2016
- 2016-10-18 CN CN201610909200.8A patent/CN106568624A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2927032Y (en) * | 2006-07-20 | 2007-07-25 | 陈锦源 | Pathological tissue treater |
| CN201378123Y (en) * | 2009-04-16 | 2010-01-06 | 赵晓辉 | Six-cylinder automatic water extractor for paraffin wax film production of biological tissue sample patch |
| CN102455261A (en) * | 2010-10-30 | 2012-05-16 | 杨燕 | Dewatering device |
| CN102879251A (en) * | 2012-09-18 | 2013-01-16 | 湖北阳光神琦医用科技有限公司 | Dehydrating and dyeing dual-function machine and control method thereof |
| CN203069607U (en) * | 2013-01-23 | 2013-07-17 | 深圳市亚辉龙生物科技有限公司 | Western blot automatic detection device |
| CN103884565A (en) * | 2014-04-02 | 2014-06-25 | 深圳市达科为医疗科技有限公司 | Pathological staining machine |
| CN105974894A (en) * | 2016-04-25 | 2016-09-28 | 温冬梅 | Medical laboratory automated assembly line reagent automatic supply method and system |
| CN206146706U (en) * | 2016-10-18 | 2017-05-03 | 东莞市鸥翼实业有限公司 | Pathology sample pre treatment device |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108760443A (en) * | 2018-05-18 | 2018-11-06 | 漯河医学高等专科学校 | A kind of fixing means of Pathologic specimen |
| CN113251751A (en) * | 2021-05-18 | 2021-08-13 | 枣庄科技职业学院 | Pathological section gradient dewatering device |
| CN113251751B (en) * | 2021-05-18 | 2022-05-03 | 枣庄科技职业学院 | Pathological section gradient dewatering device |
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Application publication date: 20170419 |
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