CN106551180A - Feedstuff additive for sea water fish compositionss and application thereof - Google Patents

Feedstuff additive for sea water fish compositionss and application thereof Download PDF

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Publication number
CN106551180A
CN106551180A CN201610948787.3A CN201610948787A CN106551180A CN 106551180 A CN106551180 A CN 106551180A CN 201610948787 A CN201610948787 A CN 201610948787A CN 106551180 A CN106551180 A CN 106551180A
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parts
feedstuff
compositionss
fish
additive
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CN201610948787.3A
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Chinese (zh)
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黎明
袁莉霞
王日昕
赵鹏远
来杭
侯承栋
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Ningbo University
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Ningbo University
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/80Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
    • Y02A40/81Aquaculture, e.g. of fish
    • Y02A40/818Alternative feeds for fish, e.g. in aquacultures

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  • Fodder In General (AREA)

Abstract

The invention discloses a kind of feedstuff additive for sea water fish compositionss and application thereof, wherein:Feed addictive composition is made up of following raw material and its parts by weight:15~30 parts of oyster, 1~5 part of Bufo siccus extracting solution, 1~5 part of Plantago depressa Willd, 0.01~0.05 part of Folium seu Cortex Nerii, 10~25 parts of Fructus Schisandrae Chinensis, 10~30 parts of Rhizoma Curcumae Longae, 5~15 parts of Rhizoma Chuanxiong, 10~20 parts of Radix Angelicae Sinensis, 10~20 parts of Fructus Lycii.The present invention is applied to marine fish, can effectively facilitate marine fish post-stress recovery.

Description

Feedstuff additive for sea water fish compositionss and application thereof
Technical field
The present invention relates to a kind of feed additive, more particularly to a kind of feedstuff additive for sea water fish compositionss and application thereof.
Background technology
As land-base cultivation technology is constantly ripe, mariculture industry enters the period of fast development.But, due to height The impact of the natural disasters such as density culture, drug dependence, offshore waters pollution, seawater salinity change and typhoon, causes sea water to be supported Breeding fish is chronically at physiological stress state, causes poor growth, immunity degradation, disease to take place frequently, and seriously hinders sea water and supports Grow the sound development of industry.In order to ensure the sustainability of mariculture industry, the approach for eliminating or alleviating that environment-stress affects is found Just become significant problem urgently to be resolved hurrily.
Environment-stress(Such as crowded, anoxia, ammonia nitrogen, heavy metal, osmotic pressure etc.)After generation, seawater fish is often through inferior colliculus Brain-hypophysis-kidney axle(HPI)By signal transmission to renal tissue, accelerate hydrocortisone to the release in blood, further activate N- Methyl-D-asparagic acid(NMDA)Receptor, produces a large amount of free radicals(ROS).Free radical builds up in fish body and can cause oxygen Change the problems such as damage, inflammatory reaction, immunosuppressant, metabolism disorder so that anorexia, dystropy, secretions occurs in the cultivation shoal of fish Increase and dead phenomenon occurs.
The content of the invention
The present invention is to provide one kind suitable for marine fish to solve above-mentioned technical problem, effectively facilitates the sea of post-stress recovery Water fish feed addictive composition and application thereof.
The present invention solve the technical scheme that adopted of above-mentioned technical problem for:Feedstuff additive for sea water fish compositionss and its use On the way, wherein:
Feed addictive composition is made up of following raw material and its parts by weight:15~30 parts of oyster, Bufo siccus are extracted 1~5 part of liquid, 1~5 part of Plantago depressa Willd, 0.01~0.05 part of Folium seu Cortex Nerii, 10~25 parts of Fructus Schisandrae Chinensis, 10~30 parts of Rhizoma Curcumae Longae, Rhizoma Chuanxiong 5~ 15 parts, 10~20 parts of Radix Angelicae Sinensis, 10~20 parts of Fructus Lycii, it is adaptable to marine fish, because the mechanism of action is still not clear, or because of synergism Make its be relieved by glutamine accumulation cause cerebral edema, reduce inflammatory reaction body is caused damage, adjust calcium it is steady State, removing free radical, protective tissue suppress the activity of P450s and glutathione transferase, suppress collagen from oxidative damage etc. Synthesis and hepatic stellate cell activity, act on significantly anti-hepatic fibrosiss, while mitigating hepatocellular degeneration necrosis, promote Liver cell regeneration, suppresses hepatic fibrosis, and serum paddy third, glutamic oxaloacetic transaminase, GOT can also reduced, anti-liver injury effect, so as to effectively promote Enter marine fish post-stress recovery, improve its survival rate;The raw meat perfume (or spice) of wherein Carnis ostreae can also play preferable attractant effect, and cover In formula, the abnormal flavour of other Chinese medicine ingredients, improves palatability.
Preferably, feed addictive composition is made up of following raw material and its parts by weight:It is 20 parts of oyster, dry 2 parts of toad extracting solution, 5 parts of Plantago depressa Willd, 0.015 part of Folium seu Cortex Nerii, 20 parts of Fructus Schisandrae Chinensis, 20 parts of Rhizoma Curcumae Longae, 10 parts of Rhizoma Chuanxiong, 15 parts of Radix Angelicae Sinensis, Chinese holly 15 parts of Fructus Lycii.
Or, feed addictive composition is made up of following raw material and its parts by weight:25 parts of oyster, Bufo siccus 1 part of extracting solution, 2 parts of Plantago depressa Willd, 0.05 part of Folium seu Cortex Nerii, 10 parts of Fructus Schisandrae Chinensis, 10 parts of Rhizoma Curcumae Longae, 50 parts of Rhizoma Chuanxiong, 20 parts of Radix Angelicae Sinensis, Fructus Lycii 10 parts.
Or, feed addictive composition is made up of following raw material and its parts by weight:15 parts of oyster, Bufo siccus 5 parts of extracting solution, 1 part of Plantago depressa Willd, 0.03 part of Folium seu Cortex Nerii, 15 parts of Fructus Schisandrae Chinensis, Rhizoma Curcumae Longae 15,15 parts of Rhizoma Chuanxiong, 10 parts of Radix Angelicae Sinensis, Fructus Lycii 20 Part.
Feed addictive composition can promote the feed additive of marine fish post-stress recovery for preparation Purposes.
Addition of the feed addictive composition in marine fish feedstuff is 5~10%.
Feed addictive composition is by being sprayed in marine fish feedstuff outside 5~6% additive capacity.
Feed addictive composition is uniformly mixed in marine fish feedstuff by 8~10% additive capacity.
Compared with prior art, it is an advantage of the current invention that:Suitable for marine fish, hence it is evident that alleviate and drawn by glutamine accumulation The cerebral edema that rises, reduce damage that inflammatory reaction caused to body, adjust calcium homeostasises, remove free radical, protective tissue is from oxygen Change damage etc., suppress the activity of P450s and glutathione transferase, suppress collage synthesis and hepatic stellate cell activity, have Significantly anti-hepatic fibrosiss effect, while mitigating hepatocellular degeneration necrosis, promotes liver cell regeneration, suppresses hepatic fibrosis, also Reduce can serum paddy third, glutamic oxaloacetic transaminase, GOT, anti-liver injury effect, so as to effectively facilitate marine fish post-stress recovery;It is wherein male The raw meat perfume (or spice) of oyster meat can also play preferable attractant effect, and cover the abnormal flavour of other Chinese medicine ingredients in formula, improve palatability.
Specific embodiment
With reference to embodiments the present invention is described in further detail.
Embodiment 1:
Oyster effective ingredient is taurine, can participate in various physiological activities for alleviating stress, such as alleviate by Glutamine accumulation cause cerebral edema, reduce inflammatory reaction body is caused damage, adjust calcium homeostasises, remove free radical, Protective tissue is from oxidative damage etc..The raw meat perfume (or spice) of Carnis ostreae can also play preferable attractant effect, and cover in formula in other The abnormal flavour of medicine composition, improves palatability;The liver of Fish is the main portions of stress damage,
Fructus Schisandrae Chinensis can reduce being raised by the glutamate pyruvate transaminase that carbon tetrachloride, thioethanolamine etc. cause, main component γ-Fructus Schisandrae Chinensis Element tool anti-liver injury effect;
Curcumin in Rhizoma Curcumae Longae can effectively suppress the activity of P450s and glutathione transferase, suppress collage synthesis and liver Dirty sternzellen activity, the effect with anti-hepatic fibrosiss;
Effective ingredient ligustrazine in Rhizoma Chuanxiong can reduce serum transaminase, and in maintaining and improving hepatic tissue, superoxide dismutase is lived Property, scavenging activated oxygen, anti-lipid peroxidation can effectively prevent hepatic fibrosiss from acting on;
Radix Angelicae Sinensis can mitigate hepatocellular degeneration necrosis, promote liver cell regeneration, suppress hepatic fibrosis, can also make serum paddy third, millet straw Transaminase reduces;
Fructus Lycii has the effect of the deposition and reduction blood fat that mitigate hepatocyte lipid.
Feedstuff additive for sea water fish compositionss and application thereof, wherein:
Feed addictive composition is made up of following raw material and its parts by weight:15~30 parts of oyster, Bufo siccus are extracted 1~5 part of liquid, 1~5 part of Plantago depressa Willd, 0.01~0.05 part of Folium seu Cortex Nerii, 10~25 parts of Fructus Schisandrae Chinensis, 10~30 parts of Rhizoma Curcumae Longae, Rhizoma Chuanxiong 5~ 15 parts, 10~20 parts of Radix Angelicae Sinensis, 10~20 parts of Fructus Lycii, it is adaptable to marine fish, because the mechanism of action is still not clear, or because of synergism Make its be relieved by glutamine accumulation cause cerebral edema, reduce inflammatory reaction body is caused damage, adjust calcium it is steady State, removing free radical, protective tissue suppress the activity of P450s and glutathione transferase, suppress collagen from oxidative damage etc. Synthesis and hepatic stellate cell activity, act on significantly anti-hepatic fibrosiss, while mitigating hepatocellular degeneration necrosis, promote Liver cell regeneration, suppresses hepatic fibrosis, and serum paddy third, glutamic oxaloacetic transaminase, GOT can also reduced, anti-liver injury effect, so as to effectively promote Enter marine fish post-stress recovery, improve its survival rate;The raw meat perfume (or spice) of wherein Carnis ostreae can also play preferable attractant effect, and cover The abnormal flavour of other Chinese medicine ingredients in formula, improves palatability, and present invention below people verifies result of the present invention by contrast experiment, if Matched group(20 parts of oyster, 20 parts of Fructus Schisandrae Chinensis, 20 parts of Rhizoma Curcumae Longae, 10 parts of Rhizoma Chuanxiong, 15 parts of Radix Angelicae Sinensis, 15 parts of Fructus Lycii);It is real Apply a group(20 parts of oyster, 2 parts of Bufo siccus extracting solution, 5 parts of Plantago depressa Willd, 0.015 part of Folium seu Cortex Nerii, 20 parts of Fructus Schisandrae Chinensis, Rhizoma Curcumae Longae 20 parts, 10 parts of Rhizoma Chuanxiong, 15 parts of Radix Angelicae Sinensis, 15 parts of Fructus Lycii), Carnis Pseudosciaenae special feed is respectively added to by 8% dosage(Guangdong perseverance is emerging Feedstuff Industry Co., Ltd, Carnis Pseudosciaenae special feed)In be configured to test feedstuff, by original body mass be(15.0±1.0)g Carnis Pseudosciaenae be exposed to ammonia nitrogen concentration be half lethal concentration water body in coerce 48h after, the experiment fish for surviving is returned to In normal water body, two treatment groups are randomly divided into, as a result such as following table:
Rate of body weight gain(%) Survival rate(%)
Matched group 5.89 27.11
Embodiment group 10.12 82.56
As can be seen from the above table, embodiment group rate of body weight gain and survival rate are higher than all matched group, show that the present invention has excellent rush Enter post-stress recovery effect, biochemistry detection finds, embodiment group Carnis Pseudosciaenae activities of antioxidant enzymes, lysozyme activity and immune globulin Bai Hanliang is all remarkably higher than matched group, and because the mechanism of action is still not clear, experimental result is still to be tested.
If matched group(20 parts of oyster, 2 parts of Bufo siccus extracting solution, 5 parts of Plantago depressa Willd, 0.015 part of Folium seu Cortex Nerii, the five tastes 20 parts of son, 20 parts of Rhizoma Curcumae Longae, 10 parts of Rhizoma Chuanxiong, 15 parts of Radix Angelicae Sinensis, 15 parts of Fructus Lycii);Embodiment group(20 parts of oyster, Bufo siccus 2 parts of extracting solution, 5 parts of Plantago depressa Willd, 0.015 part of Folium seu Cortex Nerii, 20 parts of Fructus Schisandrae Chinensis, 20 parts of Rhizoma Curcumae Longae, 10 parts of Rhizoma Chuanxiong, 15 parts of Radix Angelicae Sinensis, Fructus Lycii 15 parts of son), it is configured to test feedstuff in being respectively added to crucian carp feed and Carnis Pseudosciaenae special feed by 8% dosage, by original body mass For(15.0±1.0)After the Carassius auratuss and Carnis Pseudosciaenae of g coerce 48h in being exposed to the water body that ammonia nitrogen concentration is half lethal concentration, will deposit The experiment fish for surviving is returned in normal water body, is divided into two treatment groups, as a result such as following table:
Rate of body weight gain(%) Survival rate(%)
Matched group(Carassius auratuss) 6.72 32.11
Embodiment group(Carnis Pseudosciaenae) 10.43 81.45
As can be seen from the above table, the present invention is applied to seawater fish, is not appropriate for freshwater fish.
Preferably, feed addictive composition is made up of following raw material and its parts by weight:It is 20 parts of oyster, dry 2 parts of toad extracting solution, 5 parts of Plantago depressa Willd, 0.015 part of Folium seu Cortex Nerii, 20 parts of Fructus Schisandrae Chinensis, 20 parts of Rhizoma Curcumae Longae, 10 parts of Rhizoma Chuanxiong, 15 parts of Radix Angelicae Sinensis, Chinese holly 15 parts of Fructus Lycii.
Or, feed addictive composition is made up of following raw material and its parts by weight:25 parts of oyster, Bufo siccus 1 part of extracting solution, 2 parts of Plantago depressa Willd, 0.05 part of Folium seu Cortex Nerii, 10 parts of Fructus Schisandrae Chinensis, 10 parts of Rhizoma Curcumae Longae, 50 parts of Rhizoma Chuanxiong, 20 parts of Radix Angelicae Sinensis, Fructus Lycii 10 parts.
Or, feed addictive composition is made up of following raw material and its parts by weight:15 parts of oyster, Bufo siccus 5 parts of extracting solution, 1 part of Plantago depressa Willd, 0.03 part of Folium seu Cortex Nerii, 15 parts of Fructus Schisandrae Chinensis, Rhizoma Curcumae Longae 15,15 parts of Rhizoma Chuanxiong, 10 parts of Radix Angelicae Sinensis, Fructus Lycii 20 Part.
Feed addictive composition can promote the feed additive of marine fish post-stress recovery for preparation Purposes.
Addition of the feed addictive composition in marine fish feedstuff is 5~10%.
Feed addictive composition is by being sprayed in marine fish feedstuff outside 5~6% additive capacity.
Feed addictive composition is uniformly mixed in marine fish feedstuff by 8~10% additive capacity.
Embodiment 2:
Weigh 200 grams of oyster, 20 grams of toad extracting solution, 50 grams of Plantago depressa Willd, 0.15 gram of Folium seu Cortex Nerii, 200 grams of Fructus Schisandrae Chinensis, Rhizoma Zingiberis Recens Yellow 200 grams, 100 grams of Rhizoma Chuanxiong, 150 grams of Radix Angelicae Sinensis, 150 grams of Fructus Lycii, the co-grinding prepared feedstuff that sieves adds agent, and sieve mesh is 60, is pressed 5% addition is added into seawater fish feedstuff using trypsin method technology.
Embodiment 2:
Weigh 250 grams of oyster, 10 grams of Bufo siccus extracting solution, Plantago depressa Willd 20g, Folium seu Cortex Nerii 0.5g, Fructus Schisandrae Chinensis 100g, Rhizoma Curcumae Longae 100g, Rhizoma Chuanxiong 500g, Radix Angelicae Sinensis 200g, Fructus Lycii 100g, the co-grinding prepared feedstuff that sieves add agent, and sieve mesh is 60, by 8% addition Amount uniformly mixes into seawater fish feedstuff.
Contrast experiment 1:
200 grams of oyster, 20 grams of toad extracting solution, 50 grams of Plantago depressa Willd, 0.15 gram of Folium seu Cortex Nerii, 200 grams of Fructus Schisandrae Chinensis, Rhizoma Curcumae Longae 200 grams, 100 grams of Rhizoma Chuanxiong, 150 grams of Radix Angelicae Sinensis, 150 grams of Fructus Lycii, the co-grinding prepared feedstuff that sieves adds agent, and sieve mesh is 60, by 4%, 8%th, 12% dosage is respectively added to Carnis Pseudosciaenae special feed(Guangdong Evergreen Feed Industry Co., Ltd., the special feeding of Carnis Pseudosciaenae Material)In be configured to test feedstuff, and will not contain this additive Radix Et Rhizoma Rhei fish meal as control feed.By original body mass it is (15.0±1.0)After the Carnis Pseudosciaenae of g coerces 48h in being exposed to the water body that ammonia nitrogen concentration is half lethal concentration, by what is survived Fish is returned in normal water body for experiment, is randomly divided into two treatment groups, and a treatment group feeds three kinds of experiment feedstuffs respectively(4%、 8%、12%), another treatment group feeds control feed, and after experiment carries out two weeks, result is see the table below shown in 1.
Table 1 adds impact of the different proportion feed additive to result
Rate of body weight gain(%) Survival rate(%)
4% addition group 6.12 70.30
8% addition group 10.28 83.27
12% addition group 8.55 78.59
Matched group 2.98 30.55
As shown in Table 1, experimental group survival rate is 70~83%, and matched group survival rate is 30.55%;Experimental group rate of body weight gain be 6.12~ 10.28%, for 2.98%, biochemistry detection finds for matched group weightening, experimental group Carnis Pseudosciaenae activities of antioxidant enzymes, lysozyme activity and exempts from Epidemic disease globulin content is all remarkably higher than matched group.
Jing inventor test result indicate that, above-mentioned feed addictive composition is added to into sea water by 5~10% dosage and is supported In breeding fish feedstuff, the physiological stress phenomenon for testing fish is relieved, and survival rate is improved.Present invention operation is upper less demanding, holds Easily grasp and implement, cultured fishes and people will not be damaged.
Certainly, described above not limitation of the present invention, the present invention are also not limited to the example above.The art In the essential scope of the present invention, change, remodeling, addition or the replacement made should also belong to the present invention's to those of ordinary skill Protection domain.

Claims (6)

1. feedstuff additive for sea water fish compositionss and application thereof, it is characterised in that:The feed addictive composition is by following original Material and its parts by weight composition:15~30 parts of oyster, 1~5 part of Bufo siccus extracting solution, 1~5 part of Plantago depressa Willd, Folium seu Cortex Nerii 0.01~0.05 part, 10~25 parts of Fructus Schisandrae Chinensis, 10~30 parts of Rhizoma Curcumae Longae, 5~15 parts of Rhizoma Chuanxiong, 10~20 parts of Radix Angelicae Sinensis, Fructus Lycii 10~ 20 parts.
2. feedstuff additive for sea water fish compositionss according to claim 1 and application thereof, it is characterised in that:The feedstuff adds Plus agent compositionss are made up of following raw material and its parts by weight:20 parts of oyster, 2 parts of Bufo siccus extracting solution, Plantago depressa Willd 5 Part, 0.015 part of Folium seu Cortex Nerii, 20 parts of Fructus Schisandrae Chinensis, 20 parts of Rhizoma Curcumae Longae, 10 parts of Rhizoma Chuanxiong, 15 parts of Radix Angelicae Sinensis, 15 parts of Fructus Lycii.
3. feedstuff additive for sea water fish compositionss and application thereof, it is characterised in that:The feed addictive composition is used to prepare The purposes of the feed additive of marine fish post-stress recovery can be promoted.
4. feedstuff additive for sea water fish compositionss according to claim 3 and application thereof, it is characterised in that:The feedstuff adds Plus addition of the agent compositionss in marine fish feedstuff is 5~10%.
5. feedstuff additive for sea water fish compositionss according to claim 4 and application thereof, it is characterised in that:The feedstuff adds Plus agent compositionss are by being sprayed in marine fish feedstuff outside 5~6% additive capacity.
6. feedstuff additive for sea water fish compositionss according to claim 4 and application thereof, it is characterised in that:The feedstuff adds Plus agent compositionss are uniformly mixed in marine fish feedstuff by 8~10% additive capacity.
CN201610948787.3A 2016-10-26 2016-10-26 Feedstuff additive for sea water fish compositionss and application thereof Pending CN106551180A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108126183A (en) * 2018-01-05 2018-06-08 中国水产科学研究院长江水产研究所 Chinese herbal and crude drugs preparations of aquatic livestock anti-heat stress and preparation method thereof
CN114304445A (en) * 2022-02-22 2022-04-12 中国水产科学研究院长江水产研究所 Fish feed containing traditional Chinese medicine components, detection method and application

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CN101984844A (en) * 2010-09-21 2011-03-16 广东粤佳饲料有限公司 Disease-resisting and growth-promoting feed additive premix for marine fishes
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CN104904636A (en) * 2015-06-10 2015-09-16 浙江省海洋水产研究所 Method for artificially-induced spawning of little yellow croaker
CN105341535A (en) * 2015-12-04 2016-02-24 定远县东昇生态种养殖有限公司 High-efficiency feed capable of enhancing anti-stress capacity of penaeus vannamei and preparation method of high-efficiency feed

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Publication number Priority date Publication date Assignee Title
CN101612360A (en) * 2009-07-17 2009-12-30 肖嘉惠 The medicine of treatment hepatitis, liver cirrhosis, hepatocarcinoma
CN101984844A (en) * 2010-09-21 2011-03-16 广东粤佳饲料有限公司 Disease-resisting and growth-promoting feed additive premix for marine fishes
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108126183A (en) * 2018-01-05 2018-06-08 中国水产科学研究院长江水产研究所 Chinese herbal and crude drugs preparations of aquatic livestock anti-heat stress and preparation method thereof
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CN114304445B (en) * 2022-02-22 2023-07-18 中国水产科学研究院长江水产研究所 Fish feed containing traditional Chinese medicine components, detection method and application

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