CN106550995A - A kind of flavored milk slurry and its preparation method and application - Google Patents
A kind of flavored milk slurry and its preparation method and application Download PDFInfo
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- CN106550995A CN106550995A CN201611023051.1A CN201611023051A CN106550995A CN 106550995 A CN106550995 A CN 106550995A CN 201611023051 A CN201611023051 A CN 201611023051A CN 106550995 A CN106550995 A CN 106550995A
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- pruni salicinae
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- 239000002002 slurry Substances 0.000 title claims abstract description 29
- 235000019541 flavored milk drink Nutrition 0.000 title claims abstract description 21
- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- 241000628997 Flos Species 0.000 claims abstract description 22
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 20
- 239000001509 sodium citrate Substances 0.000 claims abstract description 19
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims abstract description 19
- 235000020185 raw untreated milk Nutrition 0.000 claims abstract description 18
- 239000002994 raw material Substances 0.000 claims abstract description 16
- 239000000843 powder Substances 0.000 claims abstract description 15
- 239000000203 mixture Substances 0.000 claims abstract description 9
- 238000001816 cooling Methods 0.000 claims abstract description 8
- 239000012467 final product Substances 0.000 claims abstract description 8
- 230000001954 sterilising effect Effects 0.000 claims abstract description 3
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 3
- 230000001804 emulsifying effect Effects 0.000 claims description 14
- 238000001035 drying Methods 0.000 claims description 7
- 239000000706 filtrate Substances 0.000 claims description 7
- 238000001914 filtration Methods 0.000 claims description 7
- 238000007654 immersion Methods 0.000 claims description 7
- 238000007789 sealing Methods 0.000 claims description 7
- 239000003814 drug Substances 0.000 claims description 4
- 208000007082 Alcoholic Fatty Liver Diseases 0.000 claims description 2
- 206010016262 Fatty liver alcoholic Diseases 0.000 claims description 2
- 208000026594 alcoholic fatty liver disease Diseases 0.000 claims description 2
- 208000010706 fatty liver disease Diseases 0.000 claims description 2
- 210000000481 breast Anatomy 0.000 claims 1
- 235000013336 milk Nutrition 0.000 abstract description 16
- 239000008267 milk Substances 0.000 abstract description 16
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- 238000000034 method Methods 0.000 abstract description 7
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- 235000019634 flavors Nutrition 0.000 abstract description 5
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- 238000007596 consolidation process Methods 0.000 abstract description 2
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- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 14
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- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
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- NIPNSKYNPDTRPC-UHFFFAOYSA-N N-[2-oxo-2-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)ethyl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C(CNC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)N1CC2=C(CC1)NN=N2 NIPNSKYNPDTRPC-UHFFFAOYSA-N 0.000 description 1
- AFCARXCZXQIEQB-UHFFFAOYSA-N N-[3-oxo-3-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)propyl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C(CCNC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)N1CC2=C(CC1)NN=N2 AFCARXCZXQIEQB-UHFFFAOYSA-N 0.000 description 1
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- SBNFWQZLDJGRLK-UHFFFAOYSA-N phenothrin Chemical compound CC1(C)C(C=C(C)C)C1C(=O)OCC1=CC=CC(OC=2C=CC=CC=2)=C1 SBNFWQZLDJGRLK-UHFFFAOYSA-N 0.000 description 1
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- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G9/00—Frozen sweets, e.g. ice confectionery, ice-cream; Mixtures therefor
- A23G9/32—Frozen sweets, e.g. ice confectionery, ice-cream; Mixtures therefor characterised by the composition containing organic or inorganic compounds
- A23G9/36—Frozen sweets, e.g. ice confectionery, ice-cream; Mixtures therefor characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G9/00—Frozen sweets, e.g. ice confectionery, ice-cream; Mixtures therefor
- A23G9/32—Frozen sweets, e.g. ice confectionery, ice-cream; Mixtures therefor characterised by the composition containing organic or inorganic compounds
- A23G9/42—Frozen sweets, e.g. ice confectionery, ice-cream; Mixtures therefor characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds, extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/41—Crassulaceae (Stonecrop family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C2240/00—Use or particular additives or ingredients
- A23C2240/15—Use of plant extracts, including purified and isolated derivatives thereof, as ingredient in dairy products
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention discloses a kind of flavored milk slurry and its preparation method and application, the flavored milk is starched and is made up of the following raw material according to weight portion：76 80 parts of raw milk, 15 parts of sweeting agent, 0.1 0.5 parts of sodium citrate, 0.5 2 parts of red Radix Pruni Salicinae extract, 37 parts of Radix Rhodiolae, 11 19 parts of Flos Rosae Rugosae.By raw milk, sweeting agent, sodium citrate mix homogeneously, and in 72 DEG C of emulsified process, red Radix Pruni Salicinae extract, Radix Rhodiolae powder is added to mix homogeneously with Flos Rosae Rugosae, it is emulsified at 68 DEG C, then it is brought rapidly up being down to room temperature to 125 DEG C of sterilizations；Aseptically homogenizing, cooling, obtains final product again.The milk slurry shelf stable of the present invention, the ice cream exquisite quality for obtaining are uniform, and consolidation is good, and melts slow, and entrance is soft and smooth, has higher sophistication and preferable expansion rate, good greasy feel and soapy feeling.Excellent flavor of the present invention, moreover it is possible to which avoid drinking the hepatic injury for bringing, with wide market prospect.
Description
Technical field
The present invention relates to food technology field, specifically a kind of flavored milk slurry and its preparation method and application.
Background technology
Ice cream is a kind of traditional frozen product, is broadly divided into two species of hard ice-cream and soft ice cream, basic
Whether difference is through cure process.Soft ice cream be often referred to it is directly getting from ice cream maker, without overcure or thing
Stream, the product directly sold with soft state, due to its non-hardened process, the temperature of soft ice cream typically -4 DEG C～-
10 DEG C, mouthfeel is mellow and full, quality is soft and smooth, is favored by more and more consumers.With increasingly hot, the sludge ice river in Henan Province in dessert market
The demand of pouring also gradually increases.Although also have minority soft ice cream to be obtained by milk slurry at present, due to soft ice cream
For the particular/special requirement of local flavor and mouthfeel etc., the milk for making soft ice cream starches many with stored under refrigeration, and its transportation needs
Whole cold chain, and the shelf-life is shorter, generally 7 days or so, use and circulation in terms of be subject to more restriction, it is impossible to meet increasingly
The demand in the soft ice cream market of growth.Existing milk slurry does not have health care in addition.
The content of the invention
It is an object of the invention to provide a kind of flavored milk slurry and its preparation method and application, to solve above-mentioned background technology
The problem of middle proposition.
For achieving the above object, the present invention provides following technical scheme：
A kind of flavored milk slurry, is made up of the following raw material according to weight portion：Raw milk 76-80 part, sweeting agent 1-5 parts, lemon
Lemon acid sodium 0.1-0.5 parts, red Radix Pruni Salicinae extract 0.5-2 parts, Radix Rhodiolae 3-7 parts, Flos Rosae Rugosae 11-19 parts.
As further scheme of the invention：The flavored milk slurry, is made up of the following raw material according to weight portion：Raw milk
77-79 parts, sweeting agent 2-4 parts, sodium citrate 0.2-0.4 parts, red Radix Pruni Salicinae extract 1-1.5 parts, Radix Rhodiolae 4-6 parts, Flos Rosae Rugosae 13-
17 parts.
As further scheme of the invention：The flavored milk slurry, is made up of the following raw material according to weight portion：Raw milk
78 parts, 3 parts of sweeting agent, 0.3 part of sodium citrate, 1.2 parts of red Radix Pruni Salicinae extract, 5 parts of Radix Rhodiolae, 15 parts of Flos Rosae Rugosae.
Another object of the present invention is to provide a kind of preparation method of flavored milk slurry, comprises the steps of：
1) preparation of red Radix Pruni Salicinae extract：Red Radix Pruni Salicinae extract is crushed, 100 mesh sieves are crossed, 7.5 times of its quality is added
35% ethanol, the sealing immersion 4h at 75 DEG C, then heated and boiled 52min, obtains filtrate after filtration；It is concentrated into original volume
20%, the cold drying at a temperature of 0-3 DEG C is obtained red Radix Pruni Salicinae extract；
2) Radix Rhodiolae crushed, cross 100 mesh sieves, Radix Rhodiolae powder is obtained standby；
3) by raw milk, sweeting agent, sodium citrate mix homogeneously, and the emulsifying 22min at a temperature of 72 DEG C, then
Red Radix Pruni Salicinae extract, Radix Rhodiolae powder is added to mix homogeneously with Flos Rosae Rugosae, and the emulsifying 10min at a temperature of 68 DEG C, it is then rapid to rise
Temperature is down to room temperature to 125 DEG C of sterilization 4min；Aseptically homogenizing, cooling, obtains final product again.
Another object of the present invention is to provide application of the flavored milk slurry in treatment alcoholic fatty liver medicine is prepared.
Compared with prior art, the invention has the beneficial effects as follows：
The milk slurry shelf stable of the present invention, can room temperature preserve 6 months, the ice cream exquisite quality for obtaining is uniform, entrance
It is soft and smooth, there are higher sophistication and preferable expansion rate, with good greasy feel and soapy feeling, have certain viscosity, together
When possess good mobility, the ice cream consolidation for obtaining is good, and melts slow.The present invention has good relieving alcoholism and protecting the liver
Effect, and which has certain curative effect to the alcoholic liver injury having occurred and that, plays the role of alleviation to its symptom.The present invention
Excellent flavor, is extensively liked by consumer so that people are while cuisines are enjoyed, moreover it is possible to which avoid drinking the hepatic injury for bringing, tool
There is wide market prospect.
Specific embodiment
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described,
Obviously, described embodiment is only a part of embodiment of the invention, rather than the embodiment of whole.Based in the present invention
Embodiment, the every other embodiment obtained under the premise of creative work is not made by those of ordinary skill in the art, all
Belong to the scope of protection of the invention.
Embodiment 1
In the embodiment of the present invention, a kind of flavored milk slurry is made up of the following raw material according to weight portion：It is 76 parts of raw milk, sweet
1 part of taste agent, 0.1 part of sodium citrate, 0.5 part of red Radix Pruni Salicinae extract, 3 parts of Radix Rhodiolae, 11 parts of Flos Rosae Rugosae.
The preparation of red Radix Pruni Salicinae extract：Red Radix Pruni Salicinae extract is crushed, 100 mesh sieves are crossed, the 35% of 7.5 times of its quality is added
Ethanol, the sealing immersion 4h at 75 DEG C, then heated and boiled 52min, obtains filtrate after filtration；The 20% of original volume is concentrated into, 0
Cold drying at a temperature of DEG C, is obtained red Radix Pruni Salicinae extract.Radix Rhodiolae is crushed, 100 mesh sieves are crossed, Radix Rhodiolae powder is obtained standby.
By raw milk, sweeting agent, sodium citrate mix homogeneously, and the emulsifying 22min at a temperature of 72 DEG C, it is subsequently adding red Radix Pruni Salicinae
Extract, Radix Rhodiolae powder are mixed homogeneously with Flos Rosae Rugosae, and the emulsifying 10min at a temperature of 68 DEG C, are then brought rapidly up to 125 DEG C killing
Room temperature is down to after bacterium 4min；Aseptically homogenizing, cooling, obtains final product again.
Embodiment 2
In the embodiment of the present invention, a kind of flavored milk slurry is made up of the following raw material according to weight portion：It is 80 parts of raw milk, sweet
5 parts of taste agent, 0.5 part of sodium citrate, 2 parts of red Radix Pruni Salicinae extract, 7 parts of Radix Rhodiolae, 19 parts of Flos Rosae Rugosae.
The preparation of red Radix Pruni Salicinae extract：Red Radix Pruni Salicinae extract is crushed, 100 mesh sieves are crossed, the 35% of 7.5 times of its quality is added
Ethanol, the sealing immersion 4h at 75 DEG C, then heated and boiled 52min, obtains filtrate after filtration；The 20% of original volume is concentrated into, 3
Cold drying at a temperature of DEG C, is obtained red Radix Pruni Salicinae extract.Radix Rhodiolae is crushed, 100 mesh sieves are crossed, Radix Rhodiolae powder is obtained standby.
By raw milk, sweeting agent, sodium citrate mix homogeneously, and the emulsifying 22min at a temperature of 72 DEG C, it is subsequently adding red Radix Pruni Salicinae
Extract, Radix Rhodiolae powder are mixed homogeneously with Flos Rosae Rugosae, and the emulsifying 10min at a temperature of 68 DEG C, are then brought rapidly up to 125 DEG C killing
Room temperature is down to after bacterium 4min；Aseptically homogenizing, cooling, obtains final product again.
Embodiment 3
In the embodiment of the present invention, a kind of flavored milk slurry is made up of the following raw material according to weight portion：It is 77 parts of raw milk, sweet
2 parts of taste agent, 0.2 part of sodium citrate, 1 part of red Radix Pruni Salicinae extract, 4 parts of Radix Rhodiolae, 13 parts of Flos Rosae Rugosae.
The preparation of red Radix Pruni Salicinae extract：Red Radix Pruni Salicinae extract is crushed, 100 mesh sieves are crossed, the 35% of 7.5 times of its quality is added
Ethanol, the sealing immersion 4h at 75 DEG C, then heated and boiled 52min, obtains filtrate after filtration；The 20% of original volume is concentrated into, 1
Cold drying at a temperature of DEG C, is obtained red Radix Pruni Salicinae extract.Radix Rhodiolae is crushed, 100 mesh sieves are crossed, Radix Rhodiolae powder is obtained standby.
By raw milk, sweeting agent, sodium citrate mix homogeneously, and the emulsifying 22min at a temperature of 72 DEG C, it is subsequently adding red Radix Pruni Salicinae
Extract, Radix Rhodiolae powder are mixed homogeneously with Flos Rosae Rugosae, and the emulsifying 10min at a temperature of 68 DEG C, are then brought rapidly up to 125 DEG C killing
Room temperature is down to after bacterium 4min；Aseptically homogenizing, cooling, obtains final product again.
Embodiment 4
In the embodiment of the present invention, a kind of flavored milk slurry is made up of the following raw material according to weight portion：It is 79 parts of raw milk, sweet
4 parts of taste agent, 0.4 part of sodium citrate, 1.5 parts of red Radix Pruni Salicinae extract, 6 parts of Radix Rhodiolae, 17 parts of Flos Rosae Rugosae.
The preparation of red Radix Pruni Salicinae extract：Red Radix Pruni Salicinae extract is crushed, 100 mesh sieves are crossed, the 35% of 7.5 times of its quality is added
Ethanol, the sealing immersion 4h at 75 DEG C, then heated and boiled 52min, obtains filtrate after filtration；The 20% of original volume is concentrated into, 1
Cold drying at a temperature of DEG C, is obtained red Radix Pruni Salicinae extract.Radix Rhodiolae is crushed, 100 mesh sieves are crossed, Radix Rhodiolae powder is obtained standby.
By raw milk, sweeting agent, sodium citrate mix homogeneously, and the emulsifying 22min at a temperature of 72 DEG C, it is subsequently adding red Radix Pruni Salicinae
Extract, Radix Rhodiolae powder are mixed homogeneously with Flos Rosae Rugosae, and the emulsifying 10min at a temperature of 68 DEG C, are then brought rapidly up to 125 DEG C killing
Room temperature is down to after bacterium 4min；Aseptically homogenizing, cooling, obtains final product again.
Embodiment 5
In the embodiment of the present invention, a kind of flavored milk slurry is made up of the following raw material according to weight portion：It is 78 parts of raw milk, sweet
3 parts of taste agent, 0.3 part of sodium citrate, 1.2 parts of red Radix Pruni Salicinae extract, 5 parts of Radix Rhodiolae, 15 parts of Flos Rosae Rugosae.
The preparation of red Radix Pruni Salicinae extract：Red Radix Pruni Salicinae extract is crushed, 100 mesh sieves are crossed, the 35% of 7.5 times of its quality is added
Ethanol, the sealing immersion 4h at 75 DEG C, then heated and boiled 52min, obtains filtrate after filtration；The 20% of original volume is concentrated into, 1
Cold drying at a temperature of DEG C, is obtained red Radix Pruni Salicinae extract.Radix Rhodiolae is crushed, 100 mesh sieves are crossed, Radix Rhodiolae powder is obtained standby.
By raw milk, sweeting agent, sodium citrate mix homogeneously, and the emulsifying 22min at a temperature of 72 DEG C, it is subsequently adding red Radix Pruni Salicinae
Extract, Radix Rhodiolae powder are mixed homogeneously with Flos Rosae Rugosae, and the emulsifying 10min at a temperature of 68 DEG C, are then brought rapidly up to 125 DEG C killing
Room temperature is down to after bacterium 4min；Aseptically homogenizing, cooling, obtains final product again.
Comparative example 1
Beyond the region of objective existence is extracted except red Radix Pruni Salicinae is not contained, its formula and step are consistent with embodiment 5.
Comparative example 2
In addition to Radix Rhodiolae, Flos Rosae Rugosae is not contained, its formula and step are consistent with embodiment 5.
Comparative example 3
In addition to red Radix Pruni Salicinae extract, Radix Rhodiolae, Flos Rosae Rugosae is not contained, its formula and step are consistent with embodiment 5.
6 acute toxicity of embodiment and chronic toxicity test
Acute toxicity test in mice：The feedstuff that mice is substituted completely using the milk slurry of embodiment of the present invention 1-5 is fed,
Continuous Observation 14 days, has no dead and undue toxicity's reaction during test, off-test, Dissection test mice, observation liver, kidney,
Spleen, stomach, the heart, lung and intestinal, are showed no abnormal change.By standard of acute toxicity, the sample belongs to nontoxic level.
Chronic toxicity test：The feedstuff that mice is substituted completely using the milk slurry of embodiment of the present invention 1-5 is fed, continuously
Feeding 90 days, as a result shows：The mice fur of the milk slurry of feeding embodiment of the present invention 1-5 is smooth, and behavioral activity is normal, drink of ingesting
Water is normal, and Normal-weight increases, and blood parameters and hematology are fluctuated within normal range, and routine urinalysis and bone marrow index are equal
Fluctuate within normal range, organize internal organs no abnormality seen, generally speaking have no that toxicity reacts.
Test from more than, the milk slurry of the present invention is safe and nontoxic.
7 animal experiment of embodiment
Kunming mouse 180 is taken, male and female half and half are randomly divided into 9 groups, and every group of male and female are each 10, wherein group 1 is blank
Group, is fed using common mouse feed, and 56 degree of strong, colourless liquor distilled from sorghum is gavaged by the dosage of 0.28mg/ (10g*1 days), daily in three times
Gavage, you can reach the drunk state of moderate；Group 2-6 is test group, and the milk paste feeding that embodiment of the present invention 1-5 is respectively adopted feeds little
Mus, and gavage 56 degree of strong, colourless liquor distilled from sorghum in feeding two days later by the dosage of 0.28mg/10g, gavage in three times daily, in process of the test
Group 7-9, the milk for feeding comparative example 1-3 are starched, and gavage 56 degree of strong, colourless liquor distilled from sorghum in feeding two days later by the dosage of 0.28mg/10g, often
It gavages in three times.It is continuous to fill wine 5 days, drunk rate, mortality rate are recorded, and puts to death survival mice after 5 days, microscopy observation hepatopathy
GSH-PX, MDA and TG level in change situation and measure liver homogenate, concrete outcome see the table below 1.
1 animal test results of table
From the result of above animal experiment, the milk slurry of the present invention can reduce the drunk rate and mortality rate of mice, and
After long-time gavages Chinese liquor, indices GSH-PX, the MDA and TG level and normal mouse difference in its liver is little, and
Microscopy does not find obvious hepar damnification yet, and result above shows, the present invention has the effect of relieving alcoholism and protecting the liver, can avoid acute
Alcoholism, preventing alcoholic liver injury.Also, understand compared with comparative experimental example, the formula just because of the present invention is constituted
Just cause the milk slurry of the present invention with so good effect with weight portion, achieve unforeseeable technique effect, its raw material group
Into being the guarantee of realizing relieving alcoholism and protecting the liver with weight portion.
The structure of the animal model of this experiment with reference to Zhao Min et al. paper " alcohol-induced acute hepatic injury model
Set up and apply " (《South China preventive medicine》The 1st phase of volume 31)；" the alcohol-induced acute hepatic injury animal of Wang Yingfang et al.
Model modeling method optimizes "；And《Function of health food assessment process and the method for inspection》Documents and materials such as (2003).
8 sensory evaluation of embodiment
Sense organ flavor evaluation is carried out to embodiment of the present invention 1-5, comparative example 1-2, full marks are 10 points, and 6 points is qualified, difference
Please 10 subjective appreciation Shi Jinhang evaluate, determine the expansion rate of ice cream obtained in the milk slurry of each embodiment, concrete outcome sees below
Table 2：
Table 2
From above result of the test, the unique raw material composition of the present invention and weight portion are also the guarantor for realizing excellent flavor
Card.Obtained in the milk slurry of various embodiments of the present invention, the expansion rate of ice cream is preferable.
9 clinical trial of embodiment
Clinical data：The present invention by taking traditional Chinese medical science alcoholic liver as an example, 100 clinical observations of Jing.Traditional Chinese medical science alcoholic liver is selected to be standard
For patient have for a long time, the history of heavy drinking, 42 degree of Chinese liquor are daily more than 2 liang, last more than 2 years；Inappetence, tired nothing
Power, lean body mass；There are slight or moderate liver fibrosis；Serum glutamic oxalacetic transaminase significantly increases, and glutamate pyruvate transaminase is normal, both
Ratio 2:1～6:1.As above symptom, you can make a definite diagnosis.Make a definite diagnosis the object of observation, all male, without other serious diseases.Age
35 years old～48 years old.
Efficacy determination：
It is effective：Symptom disappearance appetite is good, and fatigue and weak disappears, with it energetically；Become thin improvement, physical comfort；Liver fiber
Change and check that 4 indexs are all qualified；Glutamic oxaloacetic transaminase, GOT is remarkably decreased, the ratio with glutamate pyruvate transaminase<2:1.
Effectively：Inappetence, fatigue and weak, lean body mass have been alleviated；Glutamic oxaloacetic transaminase, GOT declines more than 10%.
It is invalid：Symptom is unchanged.
During clinical trial, withdraw other medicines and nutrient and healthcare products, take the milk slurry of the making of embodiment of the present invention 5, see
1 month is examined for 1 cycle.Instructions of taking：Daily 80g, takes as vegetable or snacks, and after two weeks, symptom has alleviation, clothes
After 1 month, symptom is relieved.In 100 people of clinical experiment, effective 85 people, effective 15 people, invalid 0 people, total effective rate
100%.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie
In the case of spirit or essential attributes without departing substantially from the present invention, the present invention can be realized in other specific forms.Therefore, no matter
From the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is by appended power
Profit is required rather than described above is limited, it is intended that all in the implication and scope of the equivalency of claim by falling
Change is included in the present invention.
Moreover, it will be appreciated that although this specification is been described by according to embodiment, not each embodiment is only wrapped
Containing an independent technical scheme, this narrating mode of description is only that those skilled in the art should for clarity
Using description as an entirety, the technical scheme in each embodiment can also Jing it is appropriately combined, form those skilled in the art
Understandable other embodiment.
Claims (5)
1. a kind of flavored milk is starched, it is characterised in that be made up of the following raw material according to weight portion：Raw milk 76-80 part, sweeting agent
1-5 parts, sodium citrate 0.1-0.5 parts, red Radix Pruni Salicinae extract 0.5-2 parts, Radix Rhodiolae 3-7 parts, Flos Rosae Rugosae 11-19 parts.
2. flavored milk according to claim 1 is starched, it is characterised in that be made up of the following raw material according to weight portion：Raw material
Newborn 77-79 parts, sweeting agent 2-4 parts, sodium citrate 0.2-0.4 parts, red Radix Pruni Salicinae extract 1-1.5 parts, Radix Rhodiolae 4-6 parts, Flos Rosae Rugosae
13-17 parts.
3. flavored milk according to claim 1 is starched, it is characterised in that be made up of the following raw material according to weight portion：Raw material
78 parts of breast, 3 parts of sweeting agent, 0.3 part of sodium citrate, 1.2 parts of red Radix Pruni Salicinae extract, 5 parts of Radix Rhodiolae, 15 parts of Flos Rosae Rugosae.
4. the preparation method that a kind of flavored milk as described in claim 1-3 is arbitrary is starched, it is characterised in that by following steps group
Into：
1) preparation of red Radix Pruni Salicinae extract：Red Radix Pruni Salicinae extract is crushed, 100 mesh sieves are crossed, 35% wine of 7.5 times of its quality is added
Essence, the sealing immersion 4h at 75 DEG C, then heated and boiled 52min, obtains filtrate after filtration；The 20% of original volume is concentrated into, in 0-3
Cold drying at a temperature of DEG C, is obtained red Radix Pruni Salicinae extract；
2) Radix Rhodiolae crushed, cross 100 mesh sieves, Radix Rhodiolae powder is obtained standby；
3) by raw milk, sweeting agent, sodium citrate mix homogeneously, and the emulsifying 22min at a temperature of 72 DEG C, it is subsequently adding
Red Radix Pruni Salicinae extract, Radix Rhodiolae powder are mixed homogeneously with Flos Rosae Rugosae, and the emulsifying 10min at a temperature of 68 DEG C, be then brought rapidly up to
Room temperature is down to after 125 DEG C of sterilization 4min；Aseptically homogenizing, cooling, obtains final product again.
5. application of the flavored milk slurry as described in claim 1-3 is arbitrary in treatment alcoholic fatty liver medicine is prepared.
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